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Overview

ID MAG01812
Name HKD2_bin.69
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family Gp7-AA6
Genus DAHUXD01
Species
Assembly information
Completeness (%) 85.69
Contamination (%) 1.36
GC content (%) 71.0
N50 (bp) 19,937
Genome size (bp) 4,041,327

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3339

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10146505_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 400.0
HKD2_k127_10146505_1 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 354.0
HKD2_k127_10146505_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000000000003058 210.0
HKD2_k127_10146505_3 YceI-like domain - - - 0.00000000000000000000000000000000000000000000001156 178.0
HKD2_k127_10146505_4 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000001336 171.0
HKD2_k127_10146505_5 - - - - 0.00000000000000007997 82.0
HKD2_k127_103173_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 4.779e-217 683.0
HKD2_k127_1122233_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000328 128.0
HKD2_k127_1122233_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000002599 103.0
HKD2_k127_1122233_2 Outer membrane efflux protein K18904 - - 0.0001175 53.0
HKD2_k127_113310_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 520.0
HKD2_k127_113310_1 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
HKD2_k127_113310_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000003197 140.0
HKD2_k127_113310_11 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000063 136.0
HKD2_k127_113310_12 - - - - 0.00000000000000000000003048 113.0
HKD2_k127_113310_13 Helix-turn-helix domain - - - 0.000000000000000002445 100.0
HKD2_k127_113310_14 - - - - 0.000000000001048 81.0
HKD2_k127_113310_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000382 71.0
HKD2_k127_113310_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 396.0
HKD2_k127_113310_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 295.0
HKD2_k127_113310_4 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000005322 253.0
HKD2_k127_113310_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000003777 231.0
HKD2_k127_113310_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000005618 228.0
HKD2_k127_113310_7 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000001098 218.0
HKD2_k127_113310_8 Shikimate dehydrogenase substrate binding domain K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000291 183.0
HKD2_k127_113310_9 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000001084 164.0
HKD2_k127_115773_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 548.0
HKD2_k127_115773_1 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 533.0
HKD2_k127_115773_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000001696 103.0
HKD2_k127_115773_11 MoaE protein K21142 - 2.8.1.12 0.0000000000000004671 80.0
HKD2_k127_115773_12 Bacterial membrane protein YfhO - - - 0.00000000000009641 85.0
HKD2_k127_115773_13 Cytochrome c K03889 - - 0.00000007367 65.0
HKD2_k127_115773_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 370.0
HKD2_k127_115773_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 366.0
HKD2_k127_115773_4 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 293.0
HKD2_k127_115773_5 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000006452 218.0
HKD2_k127_115773_6 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000837 203.0
HKD2_k127_115773_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000005508 156.0
HKD2_k127_115773_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000002104 152.0
HKD2_k127_115773_9 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000002314 124.0
HKD2_k127_117004_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 544.0
HKD2_k127_117004_1 Patatin-like phospholipase K06900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
HKD2_k127_117004_2 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000001069 211.0
HKD2_k127_1279960_0 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 460.0
HKD2_k127_1279960_1 DinB superfamily - - - 0.00006612 46.0
HKD2_k127_1286974_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 402.0
HKD2_k127_1286974_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000037 164.0
HKD2_k127_1286974_2 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000003689 116.0
HKD2_k127_1286974_3 Bacterial membrane protein, YfhO - - - 0.00000000000153 83.0
HKD2_k127_1286974_4 - - - - 0.0000000002547 73.0
HKD2_k127_1286974_5 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000028 65.0
HKD2_k127_1286974_6 - - - - 0.000006038 60.0
HKD2_k127_1286974_7 Bacterial membrane protein, YfhO - - - 0.0007518 53.0
HKD2_k127_1312221_0 Prokaryotic cytochrome b561 - - - 0.0 1122.0
HKD2_k127_1312221_1 formate dehydrogenase - - - 7.285e-230 744.0
HKD2_k127_1312221_10 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000007969 132.0
HKD2_k127_1312221_11 - - - - 0.00000000000000001918 85.0
HKD2_k127_1312221_12 - - - - 0.000000000000000228 93.0
HKD2_k127_1312221_16 Subtilase family - - - 0.0009972 45.0
HKD2_k127_1312221_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 592.0
HKD2_k127_1312221_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 539.0
HKD2_k127_1312221_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 434.0
HKD2_k127_1312221_5 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 376.0
HKD2_k127_1312221_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 329.0
HKD2_k127_1312221_7 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001214 241.0
HKD2_k127_1312221_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000003264 190.0
HKD2_k127_1312221_9 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000001356 164.0
HKD2_k127_1315859_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.641e-272 872.0
HKD2_k127_1315859_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 507.0
HKD2_k127_1315859_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008321 291.0
HKD2_k127_1315859_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 263.0
HKD2_k127_1315859_12 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000007195 228.0
HKD2_k127_1315859_13 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000007425 138.0
HKD2_k127_1315859_14 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000004009 93.0
HKD2_k127_1315859_15 Cell division protein FtsQ K03589 - - 0.0000000000005041 78.0
HKD2_k127_1315859_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000382 58.0
HKD2_k127_1315859_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 420.0
HKD2_k127_1315859_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 422.0
HKD2_k127_1315859_4 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 434.0
HKD2_k127_1315859_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 377.0
HKD2_k127_1315859_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 396.0
HKD2_k127_1315859_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 337.0
HKD2_k127_1315859_8 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 301.0
HKD2_k127_1315859_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HKD2_k127_1326412_0 Phosphoesterase family - - - 1.022e-219 713.0
HKD2_k127_1326412_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 460.0
HKD2_k127_1326412_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000004244 119.0
HKD2_k127_1346977_0 Protein of unknown function (DUF3604) - - - 0.0 1056.0
HKD2_k127_1346977_1 Protein of unknown function (DUF1214) - - - 1.976e-227 713.0
HKD2_k127_1346977_2 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 496.0
HKD2_k127_1346977_3 - - - - 0.000000000000000000000000000000000000000000000000000000000007419 217.0
HKD2_k127_1346977_4 NMT1-like family - - - 0.000000000000000000000000000000000000000006324 160.0
HKD2_k127_1351006_0 lysine biosynthetic process via aminoadipic acid - - - 6.117e-219 709.0
HKD2_k127_1351006_1 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 332.0
HKD2_k127_1351006_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003077 272.0
HKD2_k127_1351006_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000004522 179.0
HKD2_k127_1351006_4 phosphorelay signal transduction system - - - 0.000000000000000000000002423 111.0
HKD2_k127_1351006_5 - - - - 0.0001682 46.0
HKD2_k127_1351098_0 B12 binding domain - - - 2.312e-224 704.0
HKD2_k127_1351098_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 7.984e-222 704.0
HKD2_k127_1351098_2 IgA Peptidase M64 - - - 1.032e-210 682.0
HKD2_k127_1351098_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 491.0
HKD2_k127_1351098_4 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 354.0
HKD2_k127_1351098_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001728 266.0
HKD2_k127_1351098_6 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000669 181.0
HKD2_k127_1351098_7 - - - - 0.00000000000000000000000000000006545 144.0
HKD2_k127_1351098_8 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000004686 123.0
HKD2_k127_1360507_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.81e-217 695.0
HKD2_k127_1360507_1 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
HKD2_k127_1360507_2 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000001831 240.0
HKD2_k127_1360507_3 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000195 213.0
HKD2_k127_1360507_4 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000000003956 181.0
HKD2_k127_1360507_5 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000002694 132.0
HKD2_k127_1360507_6 CHAD - - - 0.0002229 48.0
HKD2_k127_1371072_0 Glutaryl-7-ACA acylase K06978 - - 2.321e-204 644.0
HKD2_k127_1371072_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 487.0
HKD2_k127_1371072_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 368.0
HKD2_k127_1371072_3 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000004252 211.0
HKD2_k127_1371072_4 Universal stress protein K06149 - - 0.000000000000001385 83.0
HKD2_k127_1381559_0 MacB-like periplasmic core domain - - - 3.566e-320 1005.0
HKD2_k127_1381559_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.178e-220 693.0
HKD2_k127_1381559_10 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 374.0
HKD2_k127_1381559_11 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 320.0
HKD2_k127_1381559_12 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 291.0
HKD2_k127_1381559_13 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 290.0
HKD2_k127_1381559_14 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003985 304.0
HKD2_k127_1381559_15 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000431 276.0
HKD2_k127_1381559_16 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 258.0
HKD2_k127_1381559_17 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 264.0
HKD2_k127_1381559_18 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002345 246.0
HKD2_k127_1381559_19 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002903 223.0
HKD2_k127_1381559_2 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 5.351e-213 685.0
HKD2_k127_1381559_20 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001451 220.0
HKD2_k127_1381559_21 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000003739 210.0
HKD2_k127_1381559_22 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000004863 193.0
HKD2_k127_1381559_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000001146 190.0
HKD2_k127_1381559_24 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000003163 198.0
HKD2_k127_1381559_25 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000006793 178.0
HKD2_k127_1381559_26 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000000003036 189.0
HKD2_k127_1381559_27 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000001779 184.0
HKD2_k127_1381559_28 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000001046 166.0
HKD2_k127_1381559_29 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000008221 144.0
HKD2_k127_1381559_3 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 572.0
HKD2_k127_1381559_30 Helix-hairpin-helix motif - - - 0.000000000000000000000000000000005639 139.0
HKD2_k127_1381559_31 Methyltransferase domain - - - 0.00000000000000000000000000000005095 141.0
HKD2_k127_1381559_32 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000003309 125.0
HKD2_k127_1381559_33 Cytochrome c - - - 0.00000000000000000002547 98.0
HKD2_k127_1381559_34 PFAM FecR protein - - - 0.0000000000000000001168 103.0
HKD2_k127_1381559_35 peptidyl-tyrosine sulfation - - - 0.00000000000000005063 98.0
HKD2_k127_1381559_36 fatty acid desaturase - - - 0.000000000000001158 89.0
HKD2_k127_1381559_37 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000006362 89.0
HKD2_k127_1381559_38 Universal stress protein K06149 - - 0.000000000000007848 87.0
HKD2_k127_1381559_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 570.0
HKD2_k127_1381559_40 metallopeptidase activity - - - 0.00000000000006645 83.0
HKD2_k127_1381559_41 PFAM secretion protein HlyD family protein K01993 - - 0.000000000002133 80.0
HKD2_k127_1381559_42 peptidyl-tyrosine sulfation - - - 0.000000000004215 73.0
HKD2_k127_1381559_43 Helix-hairpin-helix motif - - - 0.00000001037 66.0
HKD2_k127_1381559_46 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00001182 53.0
HKD2_k127_1381559_48 PFAM blue (type 1) copper domain protein - - - 0.0005583 51.0
HKD2_k127_1381559_49 - - - - 0.0007967 51.0
HKD2_k127_1381559_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 550.0
HKD2_k127_1381559_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 439.0
HKD2_k127_1381559_7 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 448.0
HKD2_k127_1381559_8 Belongs to the OprB family K16080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 409.0
HKD2_k127_1381559_9 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 404.0
HKD2_k127_1392433_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000007196 166.0
HKD2_k127_1392433_1 TonB-dependent receptor plug - - - 0.0000000000000000000006275 112.0
HKD2_k127_1416948_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.171e-231 724.0
HKD2_k127_1416948_1 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 528.0
HKD2_k127_1416948_11 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.00000000000000000000000000000000000000000003339 187.0
HKD2_k127_1416948_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000008496 183.0
HKD2_k127_1416948_13 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000003955 181.0
HKD2_k127_1416948_14 arylsulfatase A - - - 0.00000000000000000000000000000000000000122 170.0
HKD2_k127_1416948_15 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000002682 150.0
HKD2_k127_1416948_16 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000005274 141.0
HKD2_k127_1416948_17 Universal stress protein family - - - 0.00000000000000000000000000000001277 131.0
HKD2_k127_1416948_18 Iodothyronine deiodinase - - - 0.00000000000000000000000000001341 122.0
HKD2_k127_1416948_19 serine-type endopeptidase activity K20276 - - 0.0000000000000000000000000003493 132.0
HKD2_k127_1416948_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 467.0
HKD2_k127_1416948_20 amino acid K16238 - - 0.0000000000000000000000001068 123.0
HKD2_k127_1416948_21 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000069 88.0
HKD2_k127_1416948_23 Periplasmic copper-binding protein (NosD) - - - 0.000000001926 71.0
HKD2_k127_1416948_24 Predicted membrane protein (DUF2127) - - - 0.0000001918 61.0
HKD2_k127_1416948_26 Iodothyronine deiodinase - - - 0.000611 46.0
HKD2_k127_1416948_27 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.00085 45.0
HKD2_k127_1416948_3 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 408.0
HKD2_k127_1416948_4 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 341.0
HKD2_k127_1416948_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
HKD2_k127_1416948_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
HKD2_k127_1416948_7 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000007328 246.0
HKD2_k127_1416948_8 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000001294 267.0
HKD2_k127_1416948_9 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
HKD2_k127_1459679_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 472.0
HKD2_k127_1459679_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 467.0
HKD2_k127_1459679_10 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000008897 188.0
HKD2_k127_1459679_11 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000002139 179.0
HKD2_k127_1459679_12 - - - - 0.0000000000000000000000000000000000000000237 168.0
HKD2_k127_1459679_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001484 106.0
HKD2_k127_1459679_14 metallopeptidase activity - - - 0.0000007885 61.0
HKD2_k127_1459679_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 418.0
HKD2_k127_1459679_3 polysaccharide catabolic process K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 356.0
HKD2_k127_1459679_4 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
HKD2_k127_1459679_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 317.0
HKD2_k127_1459679_6 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 298.0
HKD2_k127_1459679_7 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 306.0
HKD2_k127_1459679_8 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004635 296.0
HKD2_k127_1459679_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000005045 240.0
HKD2_k127_1467538_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 487.0
HKD2_k127_1467538_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001427 244.0
HKD2_k127_1467538_2 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000472 183.0
HKD2_k127_1467538_3 SnoaL-like polyketide cyclase - - - 0.0000000000000000002438 90.0
HKD2_k127_1467538_4 transcriptional regulator K03892 - - 0.0000000000000002786 82.0
HKD2_k127_148031_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 383.0
HKD2_k127_148031_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008214 295.0
HKD2_k127_148031_2 nuclear chromosome segregation - - - 0.00000000000000000001414 105.0
HKD2_k127_148031_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006234 90.0
HKD2_k127_148031_4 transglycosylase K08309 - - 0.0005693 53.0
HKD2_k127_1503375_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 6.867e-274 874.0
HKD2_k127_1503375_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 586.0
HKD2_k127_1503375_10 - - - - 0.00000000000002811 83.0
HKD2_k127_1503375_11 oxidoreductase activity - - - 0.00000006458 66.0
HKD2_k127_1503375_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 573.0
HKD2_k127_1503375_3 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 428.0
HKD2_k127_1503375_4 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 370.0
HKD2_k127_1503375_5 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
HKD2_k127_1503375_6 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000004162 241.0
HKD2_k127_1503375_7 regulation of translation K03530 - - 0.00000000000000000000000000001179 137.0
HKD2_k127_1503375_8 Thioesterase superfamily - - - 0.000000000000000000000000139 115.0
HKD2_k127_1503375_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000386 92.0
HKD2_k127_1522823_0 MacB-like periplasmic core domain - - - 4.684e-279 882.0
HKD2_k127_1522823_1 Belongs to the aldehyde dehydrogenase family K00128,K00138,K10217 - 1.2.1.3,1.2.1.32,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 604.0
HKD2_k127_1522823_10 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 368.0
HKD2_k127_1522823_11 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
HKD2_k127_1522823_12 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002904 266.0
HKD2_k127_1522823_13 3-hydroxyanthranilic acid dioxygenase K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000001895 254.0
HKD2_k127_1522823_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001663 249.0
HKD2_k127_1522823_15 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000001529 207.0
HKD2_k127_1522823_16 - - - - 0.000000000000000000000000000000000000000000000000006816 185.0
HKD2_k127_1522823_17 - - - - 0.000000000000000000000000000000000000000000000003451 196.0
HKD2_k127_1522823_18 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000004687 157.0
HKD2_k127_1522823_19 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000003396 143.0
HKD2_k127_1522823_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 562.0
HKD2_k127_1522823_20 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000000000008967 155.0
HKD2_k127_1522823_21 DinB superfamily - - - 0.000000000000000000000000000000001135 137.0
HKD2_k127_1522823_22 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000001247 137.0
HKD2_k127_1522823_23 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000001798 117.0
HKD2_k127_1522823_24 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000004664 79.0
HKD2_k127_1522823_25 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000006334 72.0
HKD2_k127_1522823_26 - - - - 0.000006434 55.0
HKD2_k127_1522823_27 - - - - 0.0007322 46.0
HKD2_k127_1522823_3 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 468.0
HKD2_k127_1522823_4 FAD binding domain K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 462.0
HKD2_k127_1522823_5 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 464.0
HKD2_k127_1522823_6 methyltransferase K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 445.0
HKD2_k127_1522823_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
HKD2_k127_1522823_8 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 424.0
HKD2_k127_1522823_9 tryptophan 2,3-dioxygenase activity K00453,K03392 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11,4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 401.0
HKD2_k127_1534507_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.174e-194 630.0
HKD2_k127_1534507_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 341.0
HKD2_k127_1534507_10 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000005769 62.0
HKD2_k127_1534507_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000956 245.0
HKD2_k127_1534507_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000006149 201.0
HKD2_k127_1534507_4 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000004033 190.0
HKD2_k127_1534507_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001605 164.0
HKD2_k127_1534507_6 DinB family - - - 0.000000000000000000000002202 111.0
HKD2_k127_1534507_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000002945 68.0
HKD2_k127_1534507_9 - - - - 0.00000004085 55.0
HKD2_k127_1546226_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 561.0
HKD2_k127_1546226_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 359.0
HKD2_k127_1546226_2 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 356.0
HKD2_k127_1546226_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
HKD2_k127_1546226_4 alcohol dehydrogenase K18012 - 1.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
HKD2_k127_1546226_5 B12 binding domain K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000001068 254.0
HKD2_k127_1546226_6 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000019 166.0
HKD2_k127_1546226_7 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000001849 151.0
HKD2_k127_1546226_8 YXWGXW repeat (2 copies) - - - 0.0000000000000000000125 96.0
HKD2_k127_1546226_9 - - - - 0.00000003182 66.0
HKD2_k127_1568992_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 564.0
HKD2_k127_1568992_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 558.0
HKD2_k127_1568992_10 Bacterial Ig-like domain (group 3) K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000002597 177.0
HKD2_k127_1568992_11 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000003586 170.0
HKD2_k127_1568992_12 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000002343 162.0
HKD2_k127_1568992_13 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000004575 140.0
HKD2_k127_1568992_14 - - - - 0.000000000000000000000000000000005882 132.0
HKD2_k127_1568992_15 Glyoxalase-like domain - - - 0.0000000000000000000000000000002026 131.0
HKD2_k127_1568992_16 PhoQ Sensor - - - 0.0000001122 54.0
HKD2_k127_1568992_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 552.0
HKD2_k127_1568992_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 506.0
HKD2_k127_1568992_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 411.0
HKD2_k127_1568992_5 Transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 368.0
HKD2_k127_1568992_6 Imidazolonepropionase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 312.0
HKD2_k127_1568992_7 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003861 269.0
HKD2_k127_1568992_8 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000009606 230.0
HKD2_k127_1568992_9 DoxX - - - 0.0000000000000000000000000000000000000000000000000128 184.0
HKD2_k127_1576815_0 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 579.0
HKD2_k127_1576815_1 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 380.0
HKD2_k127_1576815_10 Thioesterase - - - 0.00000000000000000000000000001448 124.0
HKD2_k127_1576815_11 protein involved in formate dehydrogenase formation K02380 - - 0.0000000000000000000000000000323 127.0
HKD2_k127_1576815_12 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0000000000000001878 80.0
HKD2_k127_1576815_13 metallopeptidase activity K20276 - - 0.00000000000001943 89.0
HKD2_k127_1576815_14 peroxiredoxin activity - - - 0.00000000001851 77.0
HKD2_k127_1576815_2 Extradiol ring-cleavage dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 315.0
HKD2_k127_1576815_3 formate dehydrogenase K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
HKD2_k127_1576815_4 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004505 297.0
HKD2_k127_1576815_5 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000006714 231.0
HKD2_k127_1576815_6 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000616 171.0
HKD2_k127_1576815_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000007741 170.0
HKD2_k127_1576815_8 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000001083 162.0
HKD2_k127_1576815_9 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000001642 145.0
HKD2_k127_1582013_0 amino acid K03294 - - 0.000002243 59.0
HKD2_k127_1590977_0 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 503.0
HKD2_k127_1590977_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 436.0
HKD2_k127_1590977_2 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 405.0
HKD2_k127_1590977_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000142 280.0
HKD2_k127_1590977_4 peptidyl-prolyl cis-trans isomerase activity K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001971 249.0
HKD2_k127_1590977_5 lipopolysaccharide metabolic process K19804 - - 0.000000000000000000000000000000000000000000000007138 192.0
HKD2_k127_1590977_6 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000004706 104.0
HKD2_k127_1593389_0 HlyD family secretion protein - - - 0.00000000000000000000000002728 126.0
HKD2_k127_1593389_1 efflux transmembrane transporter activity - - - 0.0000004041 63.0
HKD2_k127_1620760_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 421.0
HKD2_k127_1620760_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 302.0
HKD2_k127_1620760_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001542 106.0
HKD2_k127_1620760_11 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000686 103.0
HKD2_k127_1620760_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000955 49.0
HKD2_k127_1620760_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
HKD2_k127_1620760_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000004072 207.0
HKD2_k127_1620760_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000001683 176.0
HKD2_k127_1620760_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000008598 166.0
HKD2_k127_1620760_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000609 151.0
HKD2_k127_1620760_7 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001305 166.0
HKD2_k127_1620760_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000001347 112.0
HKD2_k127_1620760_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002485 114.0
HKD2_k127_1632442_0 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 1.361e-196 626.0
HKD2_k127_1632442_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 579.0
HKD2_k127_1632442_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000001781 132.0
HKD2_k127_1632442_11 - - - - 0.0000000006938 68.0
HKD2_k127_1632442_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 455.0
HKD2_k127_1632442_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 355.0
HKD2_k127_1632442_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 350.0
HKD2_k127_1632442_5 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
HKD2_k127_1632442_6 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 321.0
HKD2_k127_1632442_7 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 317.0
HKD2_k127_1632442_8 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004667 279.0
HKD2_k127_1632442_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000009263 218.0
HKD2_k127_1647000_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 385.0
HKD2_k127_1647000_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000007679 151.0
HKD2_k127_1655946_0 Involved in galactofuranosyl biosynthesis converts UDO-GlcP to UDP-GalP catalytic activity UDP- glucopyranose UDP-galactopyranose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 496.0
HKD2_k127_1655946_1 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 428.0
HKD2_k127_1655946_2 phosphoribosylformylglycinamidine cyclo-ligase activity K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
HKD2_k127_1655946_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000006096 240.0
HKD2_k127_1655946_4 Formyl transferase K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000204 224.0
HKD2_k127_1655946_5 Psort location CytoplasmicMembrane, score - - - 0.0000002107 64.0
HKD2_k127_1655946_6 - - - - 0.0000003779 53.0
HKD2_k127_1655946_7 Psort location CytoplasmicMembrane, score - - - 0.000001295 63.0
HKD2_k127_1655946_8 glycosyl transferase family - - - 0.000005344 60.0
HKD2_k127_1660393_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1124.0
HKD2_k127_1660393_1 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 451.0
HKD2_k127_1660393_10 - - - - 0.0000000000000000000000006895 112.0
HKD2_k127_1660393_11 - - - - 0.00000000000000000000002287 109.0
HKD2_k127_1660393_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 421.0
HKD2_k127_1660393_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 395.0
HKD2_k127_1660393_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004657 284.0
HKD2_k127_1660393_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001764 282.0
HKD2_k127_1660393_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001618 277.0
HKD2_k127_1660393_7 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 245.0
HKD2_k127_1660393_8 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000009685 211.0
HKD2_k127_1660393_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD2_k127_1686614_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 610.0
HKD2_k127_1686614_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 451.0
HKD2_k127_1686614_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 303.0
HKD2_k127_1686614_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001276 269.0
HKD2_k127_1687345_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 514.0
HKD2_k127_1687345_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 475.0
HKD2_k127_1687345_10 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000001116 234.0
HKD2_k127_1687345_11 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000007646 233.0
HKD2_k127_1687345_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD2_k127_1687345_13 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000001953 193.0
HKD2_k127_1687345_14 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000009405 177.0
HKD2_k127_1687345_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002583 159.0
HKD2_k127_1687345_16 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000003852 166.0
HKD2_k127_1687345_17 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000001579 151.0
HKD2_k127_1687345_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07675 - 2.7.13.3 0.00000000000000000000000000000000000003918 157.0
HKD2_k127_1687345_19 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000003086 141.0
HKD2_k127_1687345_2 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 435.0
HKD2_k127_1687345_20 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000001579 123.0
HKD2_k127_1687345_21 methyltransferase activity K04786,K12240,K13613,K15677 - - 0.0000000000000000003255 98.0
HKD2_k127_1687345_22 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000002087 84.0
HKD2_k127_1687345_23 Yip1 domain - - - 0.00000000000002427 82.0
HKD2_k127_1687345_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000001101 83.0
HKD2_k127_1687345_25 Belongs to the UPF0109 family K06960 - - 0.000000049 59.0
HKD2_k127_1687345_26 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000003703 64.0
HKD2_k127_1687345_27 ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0006508,GO:0006605,GO:0006625,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0016043,GO:0016485,GO:0019538,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043574,GO:0044238,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564 3.4.21.53 0.00005013 56.0
HKD2_k127_1687345_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 329.0
HKD2_k127_1687345_4 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001983 286.0
HKD2_k127_1687345_5 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003983 286.0
HKD2_k127_1687345_6 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002659 274.0
HKD2_k127_1687345_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000001392 245.0
HKD2_k127_1687345_8 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003611 233.0
HKD2_k127_1687345_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000006614 247.0
HKD2_k127_1687641_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 532.0
HKD2_k127_1687641_1 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 383.0
HKD2_k127_1687641_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 369.0
HKD2_k127_1687641_3 Forkhead associated domain - - - 0.000000000000004909 83.0
HKD2_k127_1687641_4 Psort location Cytoplasmic, score - - - 0.00000003409 63.0
HKD2_k127_1687641_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000158 44.0
HKD2_k127_1698578_0 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 418.0
HKD2_k127_1708954_0 Involved in the tonB-independent uptake of proteins - - - 6.154e-236 756.0
HKD2_k127_1708954_1 Involved in the tonB-independent uptake of proteins - - - 1.681e-201 665.0
HKD2_k127_1708954_10 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000001049 141.0
HKD2_k127_1708954_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000007056 152.0
HKD2_k127_1708954_12 Doxx family K15977 - - 0.0000000000000000000000000000001122 137.0
HKD2_k127_1708954_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000001097 129.0
HKD2_k127_1708954_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 574.0
HKD2_k127_1708954_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 409.0
HKD2_k127_1708954_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 367.0
HKD2_k127_1708954_5 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 298.0
HKD2_k127_1708954_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000692 268.0
HKD2_k127_1708954_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000493 261.0
HKD2_k127_1708954_8 chlorophyll binding K03286,K03640 - - 0.000000000000000000000000000000000000000000000000000000007739 211.0
HKD2_k127_1708954_9 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000001545 180.0
HKD2_k127_1728266_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1089.0
HKD2_k127_1728266_1 PFAM Na-Ca exchanger integrin-beta4 - - - 1.115e-210 717.0
HKD2_k127_1728266_10 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 267.0
HKD2_k127_1728266_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
HKD2_k127_1728266_12 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000000000008774 201.0
HKD2_k127_1728266_13 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000007216 197.0
HKD2_k127_1728266_14 PFAM ABC-2 type transporter K01992,K09690 - - 0.00000000000000000000000000000000000000000000007438 179.0
HKD2_k127_1728266_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000003209 162.0
HKD2_k127_1728266_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002539 157.0
HKD2_k127_1728266_17 EamA-like transporter family - - - 0.0000000000000000000000000000000664 141.0
HKD2_k127_1728266_18 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000002152 114.0
HKD2_k127_1728266_19 Glycosyltransferase family 87 - - - 0.00000000000000000000008694 115.0
HKD2_k127_1728266_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.134e-201 657.0
HKD2_k127_1728266_20 Metallo-peptidase family M12 - - - 0.000000000000000001452 103.0
HKD2_k127_1728266_21 Protein conserved in bacteria - - - 0.00000000005523 76.0
HKD2_k127_1728266_22 Spore maturation protein cgeB K06320 - - 0.0002308 53.0
HKD2_k127_1728266_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 531.0
HKD2_k127_1728266_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 437.0
HKD2_k127_1728266_5 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 385.0
HKD2_k127_1728266_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 370.0
HKD2_k127_1728266_7 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 341.0
HKD2_k127_1728266_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 313.0
HKD2_k127_1728266_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 295.0
HKD2_k127_1771051_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.475e-277 874.0
HKD2_k127_1771051_1 Elongation factor G, domain IV K02355 - - 1.843e-206 662.0
HKD2_k127_1771051_10 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 437.0
HKD2_k127_1771051_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 383.0
HKD2_k127_1771051_12 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 335.0
HKD2_k127_1771051_13 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001655 297.0
HKD2_k127_1771051_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002039 295.0
HKD2_k127_1771051_15 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 299.0
HKD2_k127_1771051_16 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001475 280.0
HKD2_k127_1771051_17 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002172 263.0
HKD2_k127_1771051_18 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000306 260.0
HKD2_k127_1771051_19 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003759 244.0
HKD2_k127_1771051_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 549.0
HKD2_k127_1771051_20 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000005289 203.0
HKD2_k127_1771051_21 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000488 132.0
HKD2_k127_1771051_22 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000002146 138.0
HKD2_k127_1771051_23 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000548 122.0
HKD2_k127_1771051_24 Peptidase MA superfamily - - - 0.00000000000000001431 99.0
HKD2_k127_1771051_25 DNA-binding transcription factor activity - - - 0.0000000000003772 77.0
HKD2_k127_1771051_26 Protein of unknown function (DUF2662) - - - 0.0000000000006657 78.0
HKD2_k127_1771051_27 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.000000000007323 78.0
HKD2_k127_1771051_29 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000001016 66.0
HKD2_k127_1771051_3 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 536.0
HKD2_k127_1771051_30 VanZ like family - - - 0.0000003721 61.0
HKD2_k127_1771051_31 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000004165 51.0
HKD2_k127_1771051_32 Tetratricopeptide repeat - - - 0.000009268 59.0
HKD2_k127_1771051_33 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001219 48.0
HKD2_k127_1771051_34 - - - - 0.0005261 46.0
HKD2_k127_1771051_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 560.0
HKD2_k127_1771051_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 488.0
HKD2_k127_1771051_6 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 480.0
HKD2_k127_1771051_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 438.0
HKD2_k127_1771051_8 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 459.0
HKD2_k127_1771051_9 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 444.0
HKD2_k127_1792270_0 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 392.0
HKD2_k127_1792270_1 Cysteine dioxygenase type I - - - 0.0000000001237 69.0
HKD2_k127_1810640_0 COG3209 Rhs family protein - - - 0.0000000001681 76.0
HKD2_k127_181073_0 Heat shock 70 kDa protein K04043 - - 2.79e-308 954.0
HKD2_k127_181073_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.427e-208 660.0
HKD2_k127_181073_10 Domain of unknown function (DUF4388) - - - 0.00000004825 66.0
HKD2_k127_181073_2 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 334.0
HKD2_k127_181073_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 301.0
HKD2_k127_181073_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000006906 153.0
HKD2_k127_181073_5 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000000007056 120.0
HKD2_k127_181073_6 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000002165 107.0
HKD2_k127_181073_7 - - - - 0.000000000000000000008602 103.0
HKD2_k127_181073_8 oxidoreductase activity - - - 0.00000000000000000006771 104.0
HKD2_k127_181073_9 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000005566 67.0
HKD2_k127_1817117_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 422.0
HKD2_k127_1817117_1 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 310.0
HKD2_k127_1817117_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000003728 269.0
HKD2_k127_1817117_3 Bacterial Ig-like domain (group 3) - - - 0.00000000000000000000000000000000000000000001214 189.0
HKD2_k127_1817117_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000001039 166.0
HKD2_k127_1817117_5 photosynthesis K02453,K02656 - - 0.00004934 54.0
HKD2_k127_187034_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 349.0
HKD2_k127_187034_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000003918 177.0
HKD2_k127_187034_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000001512 156.0
HKD2_k127_187034_4 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000001064 141.0
HKD2_k127_1881187_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 561.0
HKD2_k127_1881187_1 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000004577 189.0
HKD2_k127_1881187_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002597 177.0
HKD2_k127_192050_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 579.0
HKD2_k127_192050_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 554.0
HKD2_k127_192050_2 - - - - 0.000000000000000008342 98.0
HKD2_k127_192050_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000001278 79.0
HKD2_k127_1922760_0 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000001531 218.0
HKD2_k127_1922760_1 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000008111 183.0
HKD2_k127_1922760_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000001706 183.0
HKD2_k127_1922760_3 COG4942 Membrane-bound metallopeptidase - - - 0.0000000000000000000001589 99.0
HKD2_k127_1922760_4 Domain of unknown function (DUF1844) - - - 0.00000003941 66.0
HKD2_k127_1922760_5 ASPIC and UnbV - - - 0.0003565 53.0
HKD2_k127_203005_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 350.0
HKD2_k127_203005_1 twitching motility protein PilT K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 345.0
HKD2_k127_203005_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000441 168.0
HKD2_k127_203005_3 Type II transport protein GspH K08084 - - 0.00003306 53.0
HKD2_k127_2075034_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 582.0
HKD2_k127_2075034_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 326.0
HKD2_k127_2075034_2 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000869 289.0
HKD2_k127_2075034_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 278.0
HKD2_k127_2075034_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000252 256.0
HKD2_k127_2075034_5 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000001315 173.0
HKD2_k127_2075034_6 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000001059 122.0
HKD2_k127_2075034_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000001474 119.0
HKD2_k127_2075034_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000002189 68.0
HKD2_k127_2152510_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.256e-267 847.0
HKD2_k127_2152510_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.822e-239 750.0
HKD2_k127_2152510_10 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 491.0
HKD2_k127_2152510_100 SNARE associated Golgi protein - - - 0.00000000003951 64.0
HKD2_k127_2152510_101 Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis K08906 - - 0.0000001293 58.0
HKD2_k127_2152510_102 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000007452 63.0
HKD2_k127_2152510_103 Polymerase - - - 0.0004706 52.0
HKD2_k127_2152510_104 - - - - 0.000867 52.0
HKD2_k127_2152510_11 recA bacterial DNA recombination protein K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 486.0
HKD2_k127_2152510_12 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 463.0
HKD2_k127_2152510_13 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 496.0
HKD2_k127_2152510_14 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 461.0
HKD2_k127_2152510_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 426.0
HKD2_k127_2152510_16 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 420.0
HKD2_k127_2152510_17 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 435.0
HKD2_k127_2152510_18 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 401.0
HKD2_k127_2152510_19 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 408.0
HKD2_k127_2152510_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.336e-234 737.0
HKD2_k127_2152510_20 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 399.0
HKD2_k127_2152510_21 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 385.0
HKD2_k127_2152510_22 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 359.0
HKD2_k127_2152510_23 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 367.0
HKD2_k127_2152510_24 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 347.0
HKD2_k127_2152510_25 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
HKD2_k127_2152510_26 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 321.0
HKD2_k127_2152510_27 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 317.0
HKD2_k127_2152510_28 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 311.0
HKD2_k127_2152510_29 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 310.0
HKD2_k127_2152510_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.67e-231 783.0
HKD2_k127_2152510_30 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 321.0
HKD2_k127_2152510_31 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 302.0
HKD2_k127_2152510_32 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 299.0
HKD2_k127_2152510_33 Belongs to the KdsA family K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001591 304.0
HKD2_k127_2152510_34 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
HKD2_k127_2152510_35 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001286 278.0
HKD2_k127_2152510_36 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000942 308.0
HKD2_k127_2152510_37 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
HKD2_k127_2152510_38 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001456 299.0
HKD2_k127_2152510_39 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000004934 273.0
HKD2_k127_2152510_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 626.0
HKD2_k127_2152510_40 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005051 284.0
HKD2_k127_2152510_41 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003834 260.0
HKD2_k127_2152510_42 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000506 269.0
HKD2_k127_2152510_43 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006231 258.0
HKD2_k127_2152510_44 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
HKD2_k127_2152510_45 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000001508 235.0
HKD2_k127_2152510_46 dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000006209 245.0
HKD2_k127_2152510_47 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000001015 251.0
HKD2_k127_2152510_48 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000003241 239.0
HKD2_k127_2152510_49 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000003591 240.0
HKD2_k127_2152510_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 583.0
HKD2_k127_2152510_50 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000005361 233.0
HKD2_k127_2152510_51 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000002435 217.0
HKD2_k127_2152510_52 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000002996 233.0
HKD2_k127_2152510_53 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000002849 208.0
HKD2_k127_2152510_54 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000002171 201.0
HKD2_k127_2152510_55 Peptidase S53 propeptide K08677 - - 0.00000000000000000000000000000000000000000000000000000003425 218.0
HKD2_k127_2152510_56 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000001574 195.0
HKD2_k127_2152510_57 L-serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000002995 199.0
HKD2_k127_2152510_58 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000006022 216.0
HKD2_k127_2152510_59 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000952 203.0
HKD2_k127_2152510_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 522.0
HKD2_k127_2152510_60 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000001415 201.0
HKD2_k127_2152510_61 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000001649 190.0
HKD2_k127_2152510_62 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000007625 202.0
HKD2_k127_2152510_63 - - - - 0.0000000000000000000000000000000000000000000000007938 186.0
HKD2_k127_2152510_64 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000003607 193.0
HKD2_k127_2152510_65 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000003408 181.0
HKD2_k127_2152510_66 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000001058 156.0
HKD2_k127_2152510_67 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000002328 160.0
HKD2_k127_2152510_68 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000001316 167.0
HKD2_k127_2152510_69 Transmembrane and TPR repeat-containing protein - - - 0.0000000000000000000000000000000000002106 163.0
HKD2_k127_2152510_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 522.0
HKD2_k127_2152510_70 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000001307 141.0
HKD2_k127_2152510_71 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000004828 154.0
HKD2_k127_2152510_72 MlaD protein K02067 - - 0.00000000000000000000000000000000001287 153.0
HKD2_k127_2152510_73 TIGRFAM addiction module toxin, Txe YoeB family - - - 0.00000000000000000000000000000000001433 136.0
HKD2_k127_2152510_74 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000001782 141.0
HKD2_k127_2152510_75 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000006411 148.0
HKD2_k127_2152510_76 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000002116 142.0
HKD2_k127_2152510_77 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000007251 147.0
HKD2_k127_2152510_78 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000009527 134.0
HKD2_k127_2152510_8 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 529.0
HKD2_k127_2152510_80 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000001767 119.0
HKD2_k127_2152510_81 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000001065 130.0
HKD2_k127_2152510_83 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000132 112.0
HKD2_k127_2152510_84 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000001659 126.0
HKD2_k127_2152510_85 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.00000000000000000000000001839 124.0
HKD2_k127_2152510_86 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000003787 121.0
HKD2_k127_2152510_87 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000000000003994 116.0
HKD2_k127_2152510_88 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000002942 124.0
HKD2_k127_2152510_89 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000001664 104.0
HKD2_k127_2152510_9 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 511.0
HKD2_k127_2152510_90 - - - - 0.0000000000000000000007276 109.0
HKD2_k127_2152510_91 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000001196 107.0
HKD2_k127_2152510_92 Ribosomal L32p protein family K02911 - - 0.000000000000000000003311 95.0
HKD2_k127_2152510_93 Domain of unknown function (DUF4340) - - - 0.000000000000000000005687 109.0
HKD2_k127_2152510_94 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000002342 106.0
HKD2_k127_2152510_95 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000008629 85.0
HKD2_k127_2152510_96 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000004661 81.0
HKD2_k127_2152510_97 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000003765 83.0
HKD2_k127_2152510_98 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000108 71.0
HKD2_k127_2152510_99 Thioredoxin-like - - - 0.0000000000384 72.0
HKD2_k127_2188941_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 1.285e-293 955.0
HKD2_k127_2188941_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 426.0
HKD2_k127_2188941_2 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 340.0
HKD2_k127_2188941_3 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000002884 225.0
HKD2_k127_2188941_4 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000005181 229.0
HKD2_k127_2188941_5 COG0438 Glycosyltransferase K07011 - - 0.00000000000000000000000000000000000000000000006049 190.0
HKD2_k127_2188941_6 Protein of unknown function (DUF3309) - - - 0.00000000000000004649 83.0
HKD2_k127_2188941_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000009225 67.0
HKD2_k127_2188941_8 - - - - 0.000000002116 69.0
HKD2_k127_223207_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.516e-242 760.0
HKD2_k127_223207_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 582.0
HKD2_k127_223207_2 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 529.0
HKD2_k127_223207_3 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 391.0
HKD2_k127_223207_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007076 278.0
HKD2_k127_223207_5 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000009053 233.0
HKD2_k127_223207_6 Calx-beta domain - - - 0.000000000000000000006185 97.0
HKD2_k127_223207_8 DNA-templated transcription, termination K02600,K02945 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001131 75.0
HKD2_k127_2244076_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.544e-250 799.0
HKD2_k127_2250269_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 537.0
HKD2_k127_2250269_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 265.0
HKD2_k127_2250269_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001452 214.0
HKD2_k127_2250269_3 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000001317 134.0
HKD2_k127_2250269_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000009353 71.0
HKD2_k127_2256564_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1388.0
HKD2_k127_2256564_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 2.411e-210 662.0
HKD2_k127_2256564_10 Chromate resistance exported protein - - - 0.000000000000000000001554 112.0
HKD2_k127_2256564_11 - - - - 0.000000000000000001547 87.0
HKD2_k127_2256564_12 FeoA K04758 - - 0.0004326 53.0
HKD2_k127_2256564_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.037e-209 671.0
HKD2_k127_2256564_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006931 262.0
HKD2_k127_2256564_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000009255 250.0
HKD2_k127_2256564_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001351 225.0
HKD2_k127_2256564_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000002212 206.0
HKD2_k127_2256564_7 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000007958 191.0
HKD2_k127_2256564_9 YMGG-like Gly-zipper - - - 0.00000000000000000000000003568 118.0
HKD2_k127_227349_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 6.332e-227 732.0
HKD2_k127_227349_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 557.0
HKD2_k127_227349_2 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 547.0
HKD2_k127_227349_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 339.0
HKD2_k127_227349_4 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000002765 201.0
HKD2_k127_227349_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000003729 214.0
HKD2_k127_227349_6 Domain of unknown function (DUF4136) - - - 0.00000000006074 72.0
HKD2_k127_227349_7 DinB family - - - 0.0000009166 57.0
HKD2_k127_227349_8 Periplasmic component of the Tol biopolymer transport system - - - 0.000009186 53.0
HKD2_k127_227349_9 Domain of unknown function (DUF4136) - - - 0.00007517 55.0
HKD2_k127_227550_0 4Fe-4S dicluster domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 539.0
HKD2_k127_227550_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 494.0
HKD2_k127_22786_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1358.0
HKD2_k127_22786_1 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 3e-323 1023.0
HKD2_k127_22786_10 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 296.0
HKD2_k127_22786_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 315.0
HKD2_k127_22786_12 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002926 310.0
HKD2_k127_22786_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001315 274.0
HKD2_k127_22786_14 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000006833 200.0
HKD2_k127_22786_15 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000121 156.0
HKD2_k127_22786_16 - - - - 0.00000000000000000000000000000000000005624 164.0
HKD2_k127_22786_17 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000004711 144.0
HKD2_k127_22786_18 membrane K08972 - - 0.00000000000000000000000001255 112.0
HKD2_k127_22786_19 [2Fe-2S] binding domain - - - 0.0000000000001393 70.0
HKD2_k127_22786_2 Belongs to the glycosyl hydrolase 57 family - - - 1.457e-312 979.0
HKD2_k127_22786_21 peptidyl-tyrosine sulfation - - - 0.0000008088 63.0
HKD2_k127_22786_22 Protein tyrosine kinase K12132 - 2.7.11.1 0.000005593 60.0
HKD2_k127_22786_23 - - - - 0.00005656 55.0
HKD2_k127_22786_3 helicase activity - - - 1.576e-309 967.0
HKD2_k127_22786_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.125e-304 947.0
HKD2_k127_22786_5 Alpha-glucan phosphorylase K00688 - 2.4.1.1 4.123e-217 708.0
HKD2_k127_22786_6 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 543.0
HKD2_k127_22786_7 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 467.0
HKD2_k127_22786_8 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 426.0
HKD2_k127_22786_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 339.0
HKD2_k127_2354721_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 466.0
HKD2_k127_2354721_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 432.0
HKD2_k127_2354721_2 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 421.0
HKD2_k127_2354721_3 Amino acid permease K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 343.0
HKD2_k127_2354721_4 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009632 261.0
HKD2_k127_2510734_0 Arylsulfatase A K01130 - 3.1.6.1 2.314e-279 867.0
HKD2_k127_2510734_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000001435 196.0
HKD2_k127_2510734_2 Response regulator receiver domain - - - 0.000000000000000000000005894 109.0
HKD2_k127_2510734_3 Histidine kinase-like ATPases - - - 0.0000000000000000116 84.0
HKD2_k127_2563187_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004598 240.0
HKD2_k127_2563187_3 - - - - 0.0001185 49.0
HKD2_k127_2566777_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.627e-216 687.0
HKD2_k127_2566777_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 575.0
HKD2_k127_2566777_10 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000007519 134.0
HKD2_k127_2566777_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000001527 134.0
HKD2_k127_2566777_12 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000001374 127.0
HKD2_k127_2566777_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000476 102.0
HKD2_k127_2566777_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000003696 94.0
HKD2_k127_2566777_15 peptidyl-tyrosine sulfation - - - 0.00000000005757 74.0
HKD2_k127_2566777_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 381.0
HKD2_k127_2566777_3 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 343.0
HKD2_k127_2566777_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000003194 251.0
HKD2_k127_2566777_5 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000001657 243.0
HKD2_k127_2566777_6 peptidase - - - 0.000000000000000000000000000000000000000000000000000000002891 213.0
HKD2_k127_2566777_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000001647 196.0
HKD2_k127_2566777_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001516 192.0
HKD2_k127_2566777_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000001234 134.0
HKD2_k127_2570215_0 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 366.0
HKD2_k127_2570215_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000009198 109.0
HKD2_k127_2570272_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.637e-231 728.0
HKD2_k127_2570272_1 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 610.0
HKD2_k127_2570272_10 Family of unknown function (DUF5335) - - - 0.00000006055 64.0
HKD2_k127_2570272_11 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.000176 44.0
HKD2_k127_2570272_2 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
HKD2_k127_2570272_3 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
HKD2_k127_2570272_4 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000007587 249.0
HKD2_k127_2570272_5 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000001227 240.0
HKD2_k127_2570272_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000001909 130.0
HKD2_k127_2570272_7 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000001342 118.0
HKD2_k127_2570272_8 IMP dehydrogenase activity - - - 0.0000000000000005238 85.0
HKD2_k127_2570272_9 Cbs domain K04767 - - 0.0000000000000006815 84.0
HKD2_k127_2578987_0 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 9.873e-223 721.0
HKD2_k127_2578987_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
HKD2_k127_2578987_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 417.0
HKD2_k127_2578987_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 352.0
HKD2_k127_2578987_4 DinB family - - - 0.00000000000000000000000000000000000000000000000001147 185.0
HKD2_k127_2578987_5 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000005008 157.0
HKD2_k127_2578987_6 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000003218 155.0
HKD2_k127_2578987_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000002789 140.0
HKD2_k127_2587839_0 PFAM amidohydrolase - - - 1.345e-195 634.0
HKD2_k127_2587839_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 571.0
HKD2_k127_2587839_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000395 91.0
HKD2_k127_2587839_12 PFAM SMP-30 Gluconolaconase K01179,K01181,K01218,K02014 - 3.2.1.4,3.2.1.78,3.2.1.8 0.00003333 55.0
HKD2_k127_2587839_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 531.0
HKD2_k127_2587839_3 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD2_k127_2587839_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001616 213.0
HKD2_k127_2587839_5 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HKD2_k127_2587839_6 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000002831 176.0
HKD2_k127_2587839_7 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000002132 160.0
HKD2_k127_2587839_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000002667 123.0
HKD2_k127_2587839_9 ECF sigma factor - - - 0.00000000000000000000133 96.0
HKD2_k127_2588695_0 PFAM phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000119 239.0
HKD2_k127_2588695_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002404 233.0
HKD2_k127_2588695_2 - - - - 0.000000000000000000000000000000000000000000000000000002016 204.0
HKD2_k127_2588695_3 Predicted membrane protein (DUF2157) - - - 0.000000000000002144 89.0
HKD2_k127_2588695_4 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.00004577 51.0
HKD2_k127_2614340_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 553.0
HKD2_k127_2614340_1 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 359.0
HKD2_k127_2614340_2 YXWGXW repeat (2 copies) - - - 0.000000000000002394 81.0
HKD2_k127_2619326_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.12e-199 630.0
HKD2_k127_2619326_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 329.0
HKD2_k127_2619326_2 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001533 289.0
HKD2_k127_2619326_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002971 252.0
HKD2_k127_2619326_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001072 240.0
HKD2_k127_2655495_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000051 563.0
HKD2_k127_2655495_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 477.0
HKD2_k127_2655495_10 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000007405 192.0
HKD2_k127_2655495_11 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000008416 151.0
HKD2_k127_2655495_12 - - - - 0.000000000000000000000000004171 114.0
HKD2_k127_2655495_13 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000002305 112.0
HKD2_k127_2655495_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000003937 103.0
HKD2_k127_2655495_15 Binds the 23S rRNA K02909 - - 0.00000000000000006375 80.0
HKD2_k127_2655495_16 DNA polymerase III, delta' K02340 - 2.7.7.7 0.000000001182 70.0
HKD2_k127_2655495_17 peptidyl-prolyl cis-trans isomerase activity K00645,K01802,K02597,K03769,K03770,K03771 - 2.3.1.39,5.2.1.8 0.000000002314 67.0
HKD2_k127_2655495_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 442.0
HKD2_k127_2655495_3 Peptidase S15 K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 362.0
HKD2_k127_2655495_4 transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 340.0
HKD2_k127_2655495_5 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HKD2_k127_2655495_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000785 238.0
HKD2_k127_2655495_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000001673 231.0
HKD2_k127_2655495_8 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000001601 228.0
HKD2_k127_2655495_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000006137 201.0
HKD2_k127_2689551_0 Succinyl-CoA ligase like flavodoxin domain - - - 5.2e-249 794.0
HKD2_k127_2689551_1 Amino acid permease - - - 1.706e-206 666.0
HKD2_k127_2689551_10 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 431.0
HKD2_k127_2689551_11 abc transporter atp-binding protein K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 438.0
HKD2_k127_2689551_12 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 387.0
HKD2_k127_2689551_13 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 386.0
HKD2_k127_2689551_14 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 380.0
HKD2_k127_2689551_15 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 362.0
HKD2_k127_2689551_16 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 317.0
HKD2_k127_2689551_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
HKD2_k127_2689551_18 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 311.0
HKD2_k127_2689551_19 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003511 289.0
HKD2_k127_2689551_2 heat shock protein binding - - - 2.602e-195 670.0
HKD2_k127_2689551_20 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 275.0
HKD2_k127_2689551_21 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004426 249.0
HKD2_k127_2689551_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000002395 218.0
HKD2_k127_2689551_23 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000001478 217.0
HKD2_k127_2689551_24 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000004088 215.0
HKD2_k127_2689551_25 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 - - - 0.0000000000000000000000000000000000000000000000000000002322 213.0
HKD2_k127_2689551_26 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000002905 201.0
HKD2_k127_2689551_27 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000003004 197.0
HKD2_k127_2689551_28 iron-sulfur cluster assembly K07400 - - 0.000000000000000000000000000000000000000000001951 173.0
HKD2_k127_2689551_29 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000001855 166.0
HKD2_k127_2689551_3 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 5.808e-194 617.0
HKD2_k127_2689551_30 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000002346 156.0
HKD2_k127_2689551_31 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000001025 161.0
HKD2_k127_2689551_32 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000002642 153.0
HKD2_k127_2689551_33 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000001474 140.0
HKD2_k127_2689551_34 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000004346 129.0
HKD2_k127_2689551_35 COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease K13735,K20276,K20755,K21449 - 3.4.21.121 0.0000000000000000000000000004789 132.0
HKD2_k127_2689551_36 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000007777 120.0
HKD2_k127_2689551_37 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000001262 116.0
HKD2_k127_2689551_38 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000002437 116.0
HKD2_k127_2689551_39 Pas domain - - - 0.000000000000000000000009461 117.0
HKD2_k127_2689551_4 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 594.0
HKD2_k127_2689551_40 - - - - 0.00000000000000000000001044 118.0
HKD2_k127_2689551_41 - - - - 0.0000000000000000004217 97.0
HKD2_k127_2689551_42 - - - - 0.000000000000000000646 101.0
HKD2_k127_2689551_43 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000008163 98.0
HKD2_k127_2689551_44 Universal stress protein K06149 - - 0.00000000000000027 89.0
HKD2_k127_2689551_45 Heavy-metal resistance - - - 0.000000000006417 77.0
HKD2_k127_2689551_46 Protein of unknown function (DUF962) - - - 0.000000000006993 78.0
HKD2_k127_2689551_47 mRNA catabolic process K06950 - - 0.00000001443 63.0
HKD2_k127_2689551_48 tetratricopeptide repeat - - - 0.00004318 56.0
HKD2_k127_2689551_49 Iron-sulphur cluster biosynthesis K13628 - - 0.0001752 49.0
HKD2_k127_2689551_5 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 558.0
HKD2_k127_2689551_50 Tetratricopeptide repeat-like domain - - - 0.0005033 50.0
HKD2_k127_2689551_6 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 516.0
HKD2_k127_2689551_7 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 505.0
HKD2_k127_2689551_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 516.0
HKD2_k127_2689551_9 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 451.0
HKD2_k127_2690204_0 asparagine synthase K01953 - 6.3.5.4 5.19e-196 620.0
HKD2_k127_2690204_1 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 552.0
HKD2_k127_2690204_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
HKD2_k127_2708249_0 Flavin containing amine oxidoreductase - - - 1.508e-286 889.0
HKD2_k127_2708249_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 561.0
HKD2_k127_2708249_2 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 439.0
HKD2_k127_2708249_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000001512 239.0
HKD2_k127_2709627_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.033e-229 719.0
HKD2_k127_2709627_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 453.0
HKD2_k127_2709627_2 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000004432 264.0
HKD2_k127_2729839_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1468.0
HKD2_k127_2729839_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 366.0
HKD2_k127_2729839_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000178 221.0
HKD2_k127_2740609_0 PFAM SMP-30 Gluconolaconase - - - 0.0 1017.0
HKD2_k127_2740609_1 sulfatase K01130 - 3.1.6.1 1.26e-309 950.0
HKD2_k127_2740609_10 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 395.0
HKD2_k127_2740609_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 374.0
HKD2_k127_2740609_12 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 314.0
HKD2_k127_2740609_13 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001831 273.0
HKD2_k127_2740609_14 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000003858 263.0
HKD2_k127_2740609_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005227 242.0
HKD2_k127_2740609_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000134 252.0
HKD2_k127_2740609_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000000000000000000000000000002841 254.0
HKD2_k127_2740609_18 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000006707 252.0
HKD2_k127_2740609_19 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000006335 239.0
HKD2_k127_2740609_2 Sulfatase K01130 - 3.1.6.1 5.02e-284 880.0
HKD2_k127_2740609_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.0000000000000000000000000000000000000000000000000000000004187 209.0
HKD2_k127_2740609_21 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000001774 223.0
HKD2_k127_2740609_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000002827 196.0
HKD2_k127_2740609_23 UPF0126 domain - - - 0.000000000000000000000000000000000000000000002861 177.0
HKD2_k127_2740609_24 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000003298 184.0
HKD2_k127_2740609_25 - - - - 0.000000000000000000001561 99.0
HKD2_k127_2740609_26 B3/4 domain - - - 0.00000000000000000002752 92.0
HKD2_k127_2740609_27 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000108 87.0
HKD2_k127_2740609_28 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000001961 72.0
HKD2_k127_2740609_29 Pfam:DUF422 - - - 0.00000007276 63.0
HKD2_k127_2740609_3 Sulfatase K01130 - 3.1.6.1 1.789e-261 812.0
HKD2_k127_2740609_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.683e-213 693.0
HKD2_k127_2740609_5 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.789e-207 664.0
HKD2_k127_2740609_6 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 620.0
HKD2_k127_2740609_7 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 612.0
HKD2_k127_2740609_8 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 434.0
HKD2_k127_2740609_9 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 413.0
HKD2_k127_275647_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1052.0
HKD2_k127_275647_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 9.477e-267 846.0
HKD2_k127_275647_10 CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000004568 240.0
HKD2_k127_275647_11 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000005044 240.0
HKD2_k127_275647_12 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002624 209.0
HKD2_k127_275647_13 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000001495 228.0
HKD2_k127_275647_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.00000000000000000000000000000000000000000000002375 195.0
HKD2_k127_275647_15 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000002521 152.0
HKD2_k127_275647_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000001674 124.0
HKD2_k127_275647_17 Diguanylate cyclase K07315 - 3.1.3.3 0.00000000000000000000000006731 122.0
HKD2_k127_275647_18 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000026 100.0
HKD2_k127_275647_19 Putative DNA-binding domain - - - 0.000000000000000002525 98.0
HKD2_k127_275647_2 Sugar (and other) transporter - - - 3.453e-243 760.0
HKD2_k127_275647_20 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000004483 87.0
HKD2_k127_275647_21 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000003706 94.0
HKD2_k127_275647_22 S4 RNA-binding domain K04762 - - 0.0000000000000007143 85.0
HKD2_k127_275647_23 - - - - 0.00000000000000196 85.0
HKD2_k127_275647_25 DNA-sulfur modification-associated - - - 0.000002249 60.0
HKD2_k127_275647_26 - - - - 0.00000922 57.0
HKD2_k127_275647_3 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 618.0
HKD2_k127_275647_4 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 467.0
HKD2_k127_275647_6 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 413.0
HKD2_k127_275647_7 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 349.0
HKD2_k127_275647_8 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 325.0
HKD2_k127_275647_9 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 320.0
HKD2_k127_2762201_0 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 479.0
HKD2_k127_2762201_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HKD2_k127_2762201_2 methyltransferase - - - 0.000000000000001303 87.0
HKD2_k127_2765977_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 371.0
HKD2_k127_2781603_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1088.0
HKD2_k127_2781603_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 346.0
HKD2_k127_2781603_2 Large extracellular alpha-helical protein - - - 0.000000000000000000008261 96.0
HKD2_k127_2790918_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 485.0
HKD2_k127_2790918_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000001309 66.0
HKD2_k127_2833833_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 374.0
HKD2_k127_2833833_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006756 297.0
HKD2_k127_2833833_2 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 262.0
HKD2_k127_2854754_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 502.0
HKD2_k127_2854754_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 536.0
HKD2_k127_2854754_10 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006366 282.0
HKD2_k127_2854754_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000917 269.0
HKD2_k127_2854754_12 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000008258 241.0
HKD2_k127_2854754_13 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000001062 229.0
HKD2_k127_2854754_14 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000001106 222.0
HKD2_k127_2854754_15 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HKD2_k127_2854754_16 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000004596 171.0
HKD2_k127_2854754_17 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000002924 168.0
HKD2_k127_2854754_18 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000001218 133.0
HKD2_k127_2854754_19 Thioesterase superfamily K10806 - - 0.000000000000000000000000000001703 134.0
HKD2_k127_2854754_2 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 498.0
HKD2_k127_2854754_20 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000006288 115.0
HKD2_k127_2854754_21 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000001175 82.0
HKD2_k127_2854754_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000002815 59.0
HKD2_k127_2854754_23 Uncharacterised protein family (UPF0158) - - - 0.00001788 55.0
HKD2_k127_2854754_3 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 461.0
HKD2_k127_2854754_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 422.0
HKD2_k127_2854754_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 391.0
HKD2_k127_2854754_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 359.0
HKD2_k127_2854754_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
HKD2_k127_2854754_8 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007964 287.0
HKD2_k127_2854754_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004165 287.0
HKD2_k127_288305_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 1.141e-275 859.0
HKD2_k127_288305_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 2.306e-241 766.0
HKD2_k127_288305_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 529.0
HKD2_k127_288305_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 526.0
HKD2_k127_288305_4 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000002092 201.0
HKD2_k127_288305_5 Domain of unknown function (DUF4136) - - - 0.000000000001397 81.0
HKD2_k127_2889186_0 Domain of Unknown Function (DUF748) - - - 2.22e-209 695.0
HKD2_k127_2889186_1 Major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 610.0
HKD2_k127_2889186_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000009772 182.0
HKD2_k127_2889186_11 Outer membrane efflux protein - - - 0.000000000000000000000000000001036 138.0
HKD2_k127_2889186_12 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000005106 125.0
HKD2_k127_2889186_13 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000036 128.0
HKD2_k127_2889186_14 YCII-related domain - - - 0.0000000000000000000000767 101.0
HKD2_k127_2889186_15 heme oxygenase (decyclizing) activity - - - 0.000000000000000006676 98.0
HKD2_k127_2889186_16 - - - - 0.000000000000000006789 87.0
HKD2_k127_2889186_17 Aromatic acid exporter family member 1 - - - 0.00000000000004185 83.0
HKD2_k127_2889186_2 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 592.0
HKD2_k127_2889186_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 602.0
HKD2_k127_2889186_4 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 514.0
HKD2_k127_2889186_5 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
HKD2_k127_2889186_6 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 354.0
HKD2_k127_2889186_7 Biotin-lipoyl like K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 294.0
HKD2_k127_2889186_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002094 269.0
HKD2_k127_2889186_9 - - - - 0.0000000000000000000000000000000000000000000000002213 183.0
HKD2_k127_2908312_0 Urocanase C-terminal domain K01712 - 4.2.1.49 1.314e-246 778.0
HKD2_k127_2908312_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 489.0
HKD2_k127_2908312_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00001451 59.0
HKD2_k127_2908312_11 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.00004737 53.0
HKD2_k127_2908312_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 472.0
HKD2_k127_2908312_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
HKD2_k127_2908312_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
HKD2_k127_2908312_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 409.0
HKD2_k127_2908312_6 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 331.0
HKD2_k127_2908312_7 PFAM Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002488 224.0
HKD2_k127_2908312_8 Tetratricopeptide repeat - - - 0.000000000000000006035 99.0
HKD2_k127_2908312_9 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000003045 64.0
HKD2_k127_2911897_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 549.0
HKD2_k127_2911897_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 509.0
HKD2_k127_2911897_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 374.0
HKD2_k127_2911897_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 339.0
HKD2_k127_2911897_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003034 289.0
HKD2_k127_2911897_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000005053 218.0
HKD2_k127_2911897_6 Peptidase family M1 domain - - - 0.000000000000000000003592 109.0
HKD2_k127_292649_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1079.0
HKD2_k127_292649_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.224e-243 781.0
HKD2_k127_292649_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 417.0
HKD2_k127_292649_11 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 434.0
HKD2_k127_292649_12 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 400.0
HKD2_k127_292649_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 354.0
HKD2_k127_292649_14 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 367.0
HKD2_k127_292649_15 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 340.0
HKD2_k127_292649_16 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 289.0
HKD2_k127_292649_17 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000315 286.0
HKD2_k127_292649_18 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001698 271.0
HKD2_k127_292649_19 Transglycosylase SLT domain K08307,K12204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003298 264.0
HKD2_k127_292649_2 Heat shock 70 kDa protein K04043 - - 3.98e-239 753.0
HKD2_k127_292649_20 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
HKD2_k127_292649_21 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000005656 239.0
HKD2_k127_292649_22 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000005748 225.0
HKD2_k127_292649_23 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000206 216.0
HKD2_k127_292649_24 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000007703 197.0
HKD2_k127_292649_25 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000003075 197.0
HKD2_k127_292649_26 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000002293 166.0
HKD2_k127_292649_27 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000174 175.0
HKD2_k127_292649_28 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000001873 147.0
HKD2_k127_292649_29 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000005091 154.0
HKD2_k127_292649_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.005e-195 662.0
HKD2_k127_292649_30 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000001024 136.0
HKD2_k127_292649_31 Transglycosylase SLT domain - - - 0.00000000000000000000000000000003231 134.0
HKD2_k127_292649_32 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000005524 131.0
HKD2_k127_292649_33 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000004067 121.0
HKD2_k127_292649_34 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000617 103.0
HKD2_k127_292649_35 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000915 104.0
HKD2_k127_292649_36 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000001112 91.0
HKD2_k127_292649_37 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000001436 77.0
HKD2_k127_292649_38 Modulates RecA activity K03565 - - 0.000000000001714 74.0
HKD2_k127_292649_39 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000006717 72.0
HKD2_k127_292649_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 612.0
HKD2_k127_292649_40 - - - - 0.000307 51.0
HKD2_k127_292649_41 Tetratricopeptide repeat - - - 0.0003692 52.0
HKD2_k127_292649_5 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 546.0
HKD2_k127_292649_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 534.0
HKD2_k127_292649_7 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 481.0
HKD2_k127_292649_8 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 471.0
HKD2_k127_292649_9 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 454.0
HKD2_k127_294243_0 4Fe-4S single cluster domain K06937 - - 1.297e-254 799.0
HKD2_k127_294243_1 GTP-binding protein TypA K06207 - - 5.206e-203 649.0
HKD2_k127_294243_10 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000001455 227.0
HKD2_k127_294243_11 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000001099 174.0
HKD2_k127_294243_12 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000002874 156.0
HKD2_k127_294243_13 - - - - 0.00000000000000000000000000000000006443 141.0
HKD2_k127_294243_14 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000007828 135.0
HKD2_k127_294243_15 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000001151 151.0
HKD2_k127_294243_16 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006626 99.0
HKD2_k127_294243_17 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000005757 64.0
HKD2_k127_294243_2 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 600.0
HKD2_k127_294243_3 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 546.0
HKD2_k127_294243_4 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 416.0
HKD2_k127_294243_5 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 330.0
HKD2_k127_294243_6 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 297.0
HKD2_k127_294243_7 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000008114 256.0
HKD2_k127_294243_8 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
HKD2_k127_294243_9 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000289 232.0
HKD2_k127_29790_0 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002499 254.0
HKD2_k127_29790_1 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000001403 222.0
HKD2_k127_29790_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000001016 147.0
HKD2_k127_29790_3 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000004956 137.0
HKD2_k127_29790_4 - - - - 0.000000000000000000000000000006001 135.0
HKD2_k127_29790_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000004361 104.0
HKD2_k127_29790_6 - - - - 0.0000000000000000000004136 98.0
HKD2_k127_29790_7 Transcriptional regulator - - - 0.0002392 48.0
HKD2_k127_300068_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 588.0
HKD2_k127_300068_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 550.0
HKD2_k127_300068_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 323.0
HKD2_k127_300068_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000001819 273.0
HKD2_k127_300068_4 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000002035 262.0
HKD2_k127_300068_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000004628 210.0
HKD2_k127_300068_6 Protein conserved in bacteria K09800 - - 0.00000000001474 79.0
HKD2_k127_3118253_0 Involved in the tonB-independent uptake of proteins - - - 2.25e-219 709.0
HKD2_k127_3118253_1 Involved in the tonB-independent uptake of proteins - - - 5.615e-216 695.0
HKD2_k127_3118253_2 Involved in the tonB-independent uptake of proteins - - - 6.323e-205 695.0
HKD2_k127_3118253_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 632.0
HKD2_k127_3118253_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 410.0
HKD2_k127_3118253_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000002106 174.0
HKD2_k127_3118253_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000000006185 97.0
HKD2_k127_3122762_0 Belongs to the peptidase M16 family K07263 - - 0.0 1146.0
HKD2_k127_3122762_1 cellulose binding - - - 6.969e-267 856.0
HKD2_k127_3122762_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 7.966e-255 804.0
HKD2_k127_3122762_3 Cobalamin-independent synthase, Catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 486.0
HKD2_k127_3122762_4 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 490.0
HKD2_k127_3132485_0 lipopolysaccharide transport K22110 - - 1.362e-257 805.0
HKD2_k127_3132485_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 477.0
HKD2_k127_3132485_10 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000001553 208.0
HKD2_k127_3132485_11 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000005322 189.0
HKD2_k127_3132485_12 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067,K06192 - - 0.000000000000000000000000000000000000001062 167.0
HKD2_k127_3132485_13 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000002449 159.0
HKD2_k127_3132485_14 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000006194 123.0
HKD2_k127_3132485_15 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000268 110.0
HKD2_k127_3132485_16 antisigma factor binding - - - 0.000000000000000000002683 102.0
HKD2_k127_3132485_17 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000004795 87.0
HKD2_k127_3132485_18 Protein kinase domain K12132 - 2.7.11.1 0.0000005093 62.0
HKD2_k127_3132485_19 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000001035 59.0
HKD2_k127_3132485_2 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 323.0
HKD2_k127_3132485_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 319.0
HKD2_k127_3132485_4 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002018 285.0
HKD2_k127_3132485_5 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004151 294.0
HKD2_k127_3132485_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000004137 266.0
HKD2_k127_3132485_7 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000009108 228.0
HKD2_k127_3132485_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000004164 206.0
HKD2_k127_3132485_9 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000209 211.0
HKD2_k127_314557_0 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.00000000000000000000000000000000000000008544 161.0
HKD2_k127_314557_1 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000001904 103.0
HKD2_k127_314557_2 Iron-sulfur cluster-binding domain - - - 0.00000002964 65.0
HKD2_k127_314557_3 Periplasmic copper-binding protein (NosD) - - - 0.00000003051 68.0
HKD2_k127_314557_4 transcriptional regulator, SARP family - - - 0.00001382 57.0
HKD2_k127_314557_5 Helix-turn-helix - - - 0.00002185 58.0
HKD2_k127_3171567_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 433.0
HKD2_k127_3171567_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000006333 194.0
HKD2_k127_3171567_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000000005876 157.0
HKD2_k127_3171567_3 Large extracellular alpha-helical protein K20276 - - 0.0000000000000000000000000000000000002758 153.0
HKD2_k127_3171567_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000001918 146.0
HKD2_k127_3171567_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000009422 151.0
HKD2_k127_3171567_7 TonB C terminal K03646,K03832 - - 0.00000000002245 74.0
HKD2_k127_3171567_9 TIGRFAM TonB family C-terminal domain K03832 - - 0.000003231 58.0
HKD2_k127_3217455_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 398.0
HKD2_k127_3217455_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000002092 138.0
HKD2_k127_3217455_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000001499 96.0
HKD2_k127_3239812_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.875e-287 906.0
HKD2_k127_3239812_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.913e-250 784.0
HKD2_k127_3239812_10 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 323.0
HKD2_k127_3239812_11 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005787 303.0
HKD2_k127_3239812_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000003484 286.0
HKD2_k127_3239812_13 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001167 255.0
HKD2_k127_3239812_14 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000002386 226.0
HKD2_k127_3239812_15 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001521 215.0
HKD2_k127_3239812_16 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000001122 203.0
HKD2_k127_3239812_17 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000005676 210.0
HKD2_k127_3239812_18 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000009868 190.0
HKD2_k127_3239812_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000006936 175.0
HKD2_k127_3239812_2 adenylosuccinate lyase K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 513.0
HKD2_k127_3239812_20 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.0000000000000000000000000000000000000008086 158.0
HKD2_k127_3239812_21 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000008877 148.0
HKD2_k127_3239812_22 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008697 150.0
HKD2_k127_3239812_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000001014 150.0
HKD2_k127_3239812_24 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000001918 118.0
HKD2_k127_3239812_25 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000001075 104.0
HKD2_k127_3239812_26 Acetyl propionyl-CoA carboxylase alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.000000000000000001775 93.0
HKD2_k127_3239812_27 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000186 93.0
HKD2_k127_3239812_28 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000657 81.0
HKD2_k127_3239812_29 outer membrane autotransporter barrel domain protein - - - 0.000000000001403 76.0
HKD2_k127_3239812_3 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 463.0
HKD2_k127_3239812_30 Glutaredoxin-like domain (DUF836) - - - 0.0000000901 63.0
HKD2_k127_3239812_31 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001573 61.0
HKD2_k127_3239812_32 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000009084 58.0
HKD2_k127_3239812_4 Aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 396.0
HKD2_k127_3239812_5 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 361.0
HKD2_k127_3239812_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 357.0
HKD2_k127_3239812_7 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 343.0
HKD2_k127_3239812_8 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 360.0
HKD2_k127_3239812_9 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 347.0
HKD2_k127_3280917_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.649e-241 771.0
HKD2_k127_3280917_1 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 428.0
HKD2_k127_3280917_10 arylamine N-acetyltransferase activity - - - 0.00000000005128 76.0
HKD2_k127_3280917_11 Protein of unknown function (DUF3052) - - - 0.000002413 56.0
HKD2_k127_3280917_12 Glycosyl transferase family 41 - - - 0.0003865 49.0
HKD2_k127_3280917_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 454.0
HKD2_k127_3280917_4 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001342 253.0
HKD2_k127_3280917_5 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000001319 222.0
HKD2_k127_3280917_6 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000001428 196.0
HKD2_k127_3280917_7 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000008822 191.0
HKD2_k127_3280917_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000003885 165.0
HKD2_k127_3280917_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000003121 120.0
HKD2_k127_3294086_0 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 381.0
HKD2_k127_3294086_1 YCII-related domain - - - 0.0000000000000000000000004941 116.0
HKD2_k127_3294086_2 - - - - 0.000000001235 61.0
HKD2_k127_3294086_3 - - - - 0.000007568 55.0
HKD2_k127_344833_0 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 370.0
HKD2_k127_344833_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000004528 206.0
HKD2_k127_344833_2 - - - - 0.000000000000000000000000000000000000003624 158.0
HKD2_k127_3466371_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 5.027e-207 661.0
HKD2_k127_3466371_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 540.0
HKD2_k127_3466371_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000004593 188.0
HKD2_k127_3466371_11 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000002102 174.0
HKD2_k127_3466371_12 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000009433 157.0
HKD2_k127_3466371_13 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000006104 124.0
HKD2_k127_3466371_14 cellulose binding - - - 0.0000000000000000000000001232 123.0
HKD2_k127_3466371_15 ECF sigma factor K03088 - - 0.000000000000000000000005982 111.0
HKD2_k127_3466371_2 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 456.0
HKD2_k127_3466371_3 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 443.0
HKD2_k127_3466371_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 293.0
HKD2_k127_3466371_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000008758 250.0
HKD2_k127_3466371_6 Phosphomethylpyrimidine kinase K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000003801 232.0
HKD2_k127_3466371_7 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000005144 220.0
HKD2_k127_3466371_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000006051 211.0
HKD2_k127_3466371_9 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.0000000000000000000000000000000000000000000000007596 199.0
HKD2_k127_355036_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 7.348e-206 665.0
HKD2_k127_355036_1 Peptidase, M20 K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 351.0
HKD2_k127_355036_10 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000006576 206.0
HKD2_k127_355036_11 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
HKD2_k127_355036_12 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000006388 199.0
HKD2_k127_355036_13 Transglutaminase-like superfamily - - - 0.000000000000000000000000000007299 136.0
HKD2_k127_355036_14 Methyltransferase FkbM domain - - - 0.0000000000000000000000000001421 133.0
HKD2_k127_355036_15 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000008923 128.0
HKD2_k127_355036_16 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001181 100.0
HKD2_k127_355036_17 PFAM Transcriptional regulator - - - 0.000000000005649 73.0
HKD2_k127_355036_18 - - - - 0.0000002636 56.0
HKD2_k127_355036_19 Domain of unknown function (DUF4149) - - - 0.00000665 59.0
HKD2_k127_355036_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
HKD2_k127_355036_20 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0001269 53.0
HKD2_k127_355036_21 - - - - 0.0001453 51.0
HKD2_k127_355036_3 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 291.0
HKD2_k127_355036_4 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004382 278.0
HKD2_k127_355036_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000024 269.0
HKD2_k127_355036_6 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005395 254.0
HKD2_k127_355036_7 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008491 259.0
HKD2_k127_355036_8 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
HKD2_k127_355036_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001098 222.0
HKD2_k127_357674_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 430.0
HKD2_k127_357674_1 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 427.0
HKD2_k127_357674_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000004456 146.0
HKD2_k127_357674_11 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000001484 150.0
HKD2_k127_357674_12 Putative Fe-S cluster K00380 - 1.8.1.2 0.00000000000000000004455 99.0
HKD2_k127_357674_13 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000123 86.0
HKD2_k127_357674_14 integral membrane protein - - - 0.0000000000000006158 91.0
HKD2_k127_357674_15 Pfam Cation efflux - - - 0.0000000000000317 81.0
HKD2_k127_357674_2 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 352.0
HKD2_k127_357674_3 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 353.0
HKD2_k127_357674_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 315.0
HKD2_k127_357674_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
HKD2_k127_357674_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000144 248.0
HKD2_k127_357674_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000007449 230.0
HKD2_k127_357674_8 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000001587 219.0
HKD2_k127_357674_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000001071 228.0
HKD2_k127_364204_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 385.0
HKD2_k127_364204_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 392.0
HKD2_k127_378688_0 Prolyl oligopeptidase - - - 3.823e-255 802.0
HKD2_k127_378688_1 Involved in the tonB-independent uptake of proteins - - - 1.367e-211 692.0
HKD2_k127_378688_10 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 398.0
HKD2_k127_378688_11 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 368.0
HKD2_k127_378688_12 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
HKD2_k127_378688_13 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008185 299.0
HKD2_k127_378688_14 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000002262 201.0
HKD2_k127_378688_15 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10036 - - 0.00000000000000000000000000000000000000000000000000000005401 224.0
HKD2_k127_378688_16 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000004128 189.0
HKD2_k127_378688_17 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000003748 174.0
HKD2_k127_378688_18 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000001163 143.0
HKD2_k127_378688_19 Citrate transporter - - - 0.0000000000000000000000000000004311 137.0
HKD2_k127_378688_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 1.443e-211 675.0
HKD2_k127_378688_20 PFAM PIN domain - - - 0.0000000000000000000000000004768 121.0
HKD2_k127_378688_21 Domain of unknown function (DUF4412) - - - 0.000000000000000002925 101.0
HKD2_k127_378688_22 positive regulation of growth - - - 0.0000000000000001512 93.0
HKD2_k127_378688_23 Transcriptional regulator - - - 0.0000000000000001637 94.0
HKD2_k127_378688_24 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.000000000001485 72.0
HKD2_k127_378688_25 FHA domain - - - 0.0000001251 65.0
HKD2_k127_378688_3 Ammonium Transporter K03320 - - 7.628e-202 636.0
HKD2_k127_378688_4 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 611.0
HKD2_k127_378688_5 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 489.0
HKD2_k127_378688_6 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 481.0
HKD2_k127_378688_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 492.0
HKD2_k127_378688_8 Peptidase family M49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 473.0
HKD2_k127_378688_9 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 441.0
HKD2_k127_3843463_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 1.575e-281 902.0
HKD2_k127_3843463_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.33e-211 675.0
HKD2_k127_3843463_10 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000001361 237.0
HKD2_k127_3843463_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HKD2_k127_3843463_12 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000006523 160.0
HKD2_k127_3843463_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.0000000000000000000000000000000000000002696 168.0
HKD2_k127_3843463_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000002452 167.0
HKD2_k127_3843463_15 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000008089 142.0
HKD2_k127_3843463_16 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000002471 149.0
HKD2_k127_3843463_17 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005529 141.0
HKD2_k127_3843463_18 domain, Protein - - - 0.00000000000000000000000002275 126.0
HKD2_k127_3843463_19 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000001032 110.0
HKD2_k127_3843463_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 477.0
HKD2_k127_3843463_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000001194 105.0
HKD2_k127_3843463_21 - - - - 0.00000000000000000000125 106.0
HKD2_k127_3843463_22 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000002292 82.0
HKD2_k127_3843463_23 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000003055 60.0
HKD2_k127_3843463_3 peptidase K01415,K07386 - 3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 430.0
HKD2_k127_3843463_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 367.0
HKD2_k127_3843463_5 Pfam:Arch_ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
HKD2_k127_3843463_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007812 284.0
HKD2_k127_3843463_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 278.0
HKD2_k127_3843463_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 270.0
HKD2_k127_3843463_9 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000005435 247.0
HKD2_k127_3854556_0 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 410.0
HKD2_k127_3854556_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 356.0
HKD2_k127_3854556_2 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000001559 158.0
HKD2_k127_3854556_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000001648 123.0
HKD2_k127_3865639_0 ATPase activity K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 439.0
HKD2_k127_3865639_1 Sulfate ABC transporter substrate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000001484 199.0
HKD2_k127_3865639_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000001389 191.0
HKD2_k127_3865639_3 ATPase-coupled sulfate transmembrane transporter activity K02046,K02047 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000003922 198.0
HKD2_k127_3865639_4 TRANSCRIPTIONal - - - 0.00000000000000000000000000000005729 126.0
HKD2_k127_3865639_5 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000008465 123.0
HKD2_k127_3865639_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.0000000001309 65.0
HKD2_k127_3865639_7 - - - - 0.00000007995 64.0
HKD2_k127_3868146_0 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 538.0
HKD2_k127_3868146_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 486.0
HKD2_k127_3868146_10 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000007281 176.0
HKD2_k127_3868146_11 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000156 176.0
HKD2_k127_3868146_12 PRC-barrel domain - - - 0.000000000000000000000000000000000000000003729 157.0
HKD2_k127_3868146_13 FAD binding domain - - - 0.000000000000000000000000000000001226 149.0
HKD2_k127_3868146_14 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000004818 104.0
HKD2_k127_3868146_15 Regulatory protein, FmdB family - - - 0.000000000000000007874 86.0
HKD2_k127_3868146_16 Methyltransferase domain - - - 0.00000000000000009685 94.0
HKD2_k127_3868146_17 - - - - 0.00000000001866 77.0
HKD2_k127_3868146_18 Alpha/beta hydrolase family - - - 0.00000000005177 76.0
HKD2_k127_3868146_19 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000003008 74.0
HKD2_k127_3868146_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 374.0
HKD2_k127_3868146_20 COG0642 Signal transduction histidine kinase - - - 0.0002769 49.0
HKD2_k127_3868146_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 358.0
HKD2_k127_3868146_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004282 282.0
HKD2_k127_3868146_5 lipoprotein localization to outer membrane K02004,K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000857 281.0
HKD2_k127_3868146_6 molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000003188 244.0
HKD2_k127_3868146_7 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000003521 241.0
HKD2_k127_3868146_8 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000002709 205.0
HKD2_k127_3868146_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000001365 197.0
HKD2_k127_3883150_0 PFAM NAD-dependent epimerase dehydratase - - - 7.949e-199 630.0
HKD2_k127_3883150_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 632.0
HKD2_k127_3883150_10 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000004057 211.0
HKD2_k127_3883150_11 - - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
HKD2_k127_3883150_12 Helix-turn-helix domain K02806 - - 0.000000000000000000000000000000000000000000000000000000343 201.0
HKD2_k127_3883150_13 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000002544 181.0
HKD2_k127_3883150_14 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000000143 166.0
HKD2_k127_3883150_15 response to pH - - - 0.000000000000000000000000000000004108 142.0
HKD2_k127_3883150_16 - - - - 0.00000000000000000000000000000002969 130.0
HKD2_k127_3883150_18 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.0000000000107 76.0
HKD2_k127_3883150_19 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000003554 64.0
HKD2_k127_3883150_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 575.0
HKD2_k127_3883150_20 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.0006042 51.0
HKD2_k127_3883150_3 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 520.0
HKD2_k127_3883150_4 PFAM sigma-54 factor interaction domain-containing protein K00575,K12266 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 501.0
HKD2_k127_3883150_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 451.0
HKD2_k127_3883150_6 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 403.0
HKD2_k127_3883150_7 NmrA-like family K07118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 331.0
HKD2_k127_3883150_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 292.0
HKD2_k127_3883150_9 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004699 305.0
HKD2_k127_3884744_0 DEAD DEAH box K03724 - - 0.0 1857.0
HKD2_k127_3884744_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 1.231e-305 954.0
HKD2_k127_3884744_10 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000004848 201.0
HKD2_k127_3884744_11 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000005106 172.0
HKD2_k127_3884744_12 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000001223 164.0
HKD2_k127_3884744_13 glyoxalase III activity - - - 0.0000000000000000000000000000000000005066 148.0
HKD2_k127_3884744_14 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000001049 153.0
HKD2_k127_3884744_15 Phage integrase family - - - 0.00000000000000000000000000000005118 134.0
HKD2_k127_3884744_16 Permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000001288 129.0
HKD2_k127_3884744_18 Methyltransferase domain - - - 0.0000000000000000262 92.0
HKD2_k127_3884744_19 - - - - 0.000000000000000461 84.0
HKD2_k127_3884744_2 PFAM Glycoside hydrolase 15-related K01178 - 3.2.1.3 1.285e-273 852.0
HKD2_k127_3884744_20 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.00000000000002643 75.0
HKD2_k127_3884744_21 - - - - 0.0000000000002281 81.0
HKD2_k127_3884744_22 COG3415 Transposase and inactivated derivatives K07499 - - 0.000000000002492 73.0
HKD2_k127_3884744_23 Tyrosine phosphatase family - - - 0.000000000003222 76.0
HKD2_k127_3884744_25 FlgD Ig-like domain - - - 0.000000007452 64.0
HKD2_k127_3884744_26 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000279 63.0
HKD2_k127_3884744_28 UPF0391 membrane protein - - - 0.0007563 44.0
HKD2_k127_3884744_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.052e-267 854.0
HKD2_k127_3884744_4 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 411.0
HKD2_k127_3884744_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 405.0
HKD2_k127_3884744_6 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004533 291.0
HKD2_k127_3884744_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000002014 236.0
HKD2_k127_3884744_8 Domain of unknown function (DUF4209) - - - 0.0000000000000000000000000000000000000000000000000000000000001037 235.0
HKD2_k127_3884744_9 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000002903 185.0
HKD2_k127_3898295_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1260.0
HKD2_k127_3898295_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 376.0
HKD2_k127_3898295_10 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000111 193.0
HKD2_k127_3898295_11 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000002927 184.0
HKD2_k127_3898295_12 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000001325 159.0
HKD2_k127_3898295_13 ABC transporter K01990 - - 0.00000000000000000000000000000000000002574 166.0
HKD2_k127_3898295_14 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000001852 149.0
HKD2_k127_3898295_15 signal transduction histidine kinase K07642 - 2.7.13.3 0.000000000000000000000001674 117.0
HKD2_k127_3898295_16 efflux transmembrane transporter activity - - - 0.0000000000000000000000882 103.0
HKD2_k127_3898295_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000002798 107.0
HKD2_k127_3898295_18 PFAM secretion protein HlyD K02005 - - 0.00000000000000000007405 101.0
HKD2_k127_3898295_19 Transcriptional regulator - - - 0.000000000000000001581 93.0
HKD2_k127_3898295_2 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 380.0
HKD2_k127_3898295_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000007746 82.0
HKD2_k127_3898295_21 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000004471 68.0
HKD2_k127_3898295_22 PFAM Oxidoreductase, molybdopterin binding - - - 0.000000001108 66.0
HKD2_k127_3898295_24 - - - - 0.00001629 52.0
HKD2_k127_3898295_25 WD40 repeats - - - 0.0004506 54.0
HKD2_k127_3898295_26 polyamine oxidase 5 K12259 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016647,GO:0040034,GO:0044424,GO:0044464,GO:0048506,GO:0048509,GO:0048510,GO:0050789,GO:0050793,GO:0055114,GO:0065007,GO:1990534 1.5.3.16 0.0006895 50.0
HKD2_k127_3898295_3 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 347.0
HKD2_k127_3898295_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
HKD2_k127_3898295_5 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 332.0
HKD2_k127_3898295_6 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002855 302.0
HKD2_k127_3898295_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001077 258.0
HKD2_k127_3898295_8 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
HKD2_k127_3898295_9 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000002606 239.0
HKD2_k127_3899081_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 3.505e-235 747.0
HKD2_k127_3899081_1 Voltage gated chloride channel - - - 3.381e-218 692.0
HKD2_k127_3899081_10 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 334.0
HKD2_k127_3899081_11 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 346.0
HKD2_k127_3899081_12 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 319.0
HKD2_k127_3899081_13 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000959 281.0
HKD2_k127_3899081_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004242 249.0
HKD2_k127_3899081_15 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001381 260.0
HKD2_k127_3899081_16 MoeZ MoeB domain K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000002835 252.0
HKD2_k127_3899081_17 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004989 235.0
HKD2_k127_3899081_18 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000827 209.0
HKD2_k127_3899081_19 Metal-dependent phosphoesterase K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000001579 195.0
HKD2_k127_3899081_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 629.0
HKD2_k127_3899081_20 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000002418 190.0
HKD2_k127_3899081_21 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000002783 184.0
HKD2_k127_3899081_22 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000007142 138.0
HKD2_k127_3899081_23 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000002472 133.0
HKD2_k127_3899081_24 Winged helix DNA-binding domain - - - 0.00000000000000000000008188 108.0
HKD2_k127_3899081_3 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 504.0
HKD2_k127_3899081_4 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 420.0
HKD2_k127_3899081_5 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 403.0
HKD2_k127_3899081_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 389.0
HKD2_k127_3899081_7 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 363.0
HKD2_k127_3899081_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 344.0
HKD2_k127_3899081_9 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 347.0
HKD2_k127_3904573_0 Sodium/calcium exchanger protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 437.0
HKD2_k127_3904573_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004002 248.0
HKD2_k127_3911570_0 Carboxypeptidase regulatory-like domain - - - 2.057e-207 681.0
HKD2_k127_3911570_1 - - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD2_k127_3911570_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000002098 171.0
HKD2_k127_3911570_3 Radical SAM superfamily - - - 0.00000000000000000000002128 113.0
HKD2_k127_3919890_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 442.0
HKD2_k127_3919890_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000003581 203.0
HKD2_k127_3919890_2 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000232 158.0
HKD2_k127_3919890_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000001548 140.0
HKD2_k127_3923016_0 Formamidopyrimidine-DNA glycosylase H2TH domain K05522,K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0003906,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0090304,GO:0097159,GO:0097506,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
HKD2_k127_3923016_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000004899 228.0
HKD2_k127_3923016_2 chain release factor K15034 - - 0.000000000000000000000000000002009 134.0
HKD2_k127_3923016_3 Sel1-like repeats. K07126 - - 0.000000000000000000000000004695 117.0
HKD2_k127_3923016_4 Serine threonine-protein kinase - - - 0.0000328 57.0
HKD2_k127_3923710_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 479.0
HKD2_k127_3923710_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 443.0
HKD2_k127_3923710_10 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000005619 177.0
HKD2_k127_3923710_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000004095 134.0
HKD2_k127_3923710_12 membrane - GO:0005575,GO:0016020 - 0.00000000000000000000001283 115.0
HKD2_k127_3923710_13 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000007641 111.0
HKD2_k127_3923710_14 - - - - 0.000000000001162 76.0
HKD2_k127_3923710_15 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000006877 76.0
HKD2_k127_3923710_16 Gram-negative bacterial TonB protein C-terminal - - - 0.00000003244 67.0
HKD2_k127_3923710_17 PFAM phosphatidate cytidylyltransferase - - - 0.000596 52.0
HKD2_k127_3923710_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 450.0
HKD2_k127_3923710_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 405.0
HKD2_k127_3923710_4 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 362.0
HKD2_k127_3923710_5 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 348.0
HKD2_k127_3923710_6 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
HKD2_k127_3923710_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000001892 243.0
HKD2_k127_3923710_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000003628 235.0
HKD2_k127_3923710_9 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
HKD2_k127_3924530_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 312.0
HKD2_k127_3924530_1 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001647 299.0
HKD2_k127_3924530_2 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001913 283.0
HKD2_k127_3924530_3 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
HKD2_k127_3924530_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000001384 228.0
HKD2_k127_3924530_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000002854 214.0
HKD2_k127_3924530_6 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000002261 156.0
HKD2_k127_3924530_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000007533 138.0
HKD2_k127_3932133_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1137.0
HKD2_k127_3932133_1 Oligoendopeptidase f - - - 4.619e-241 759.0
HKD2_k127_3932133_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000596 288.0
HKD2_k127_3942173_0 Insulinase (Peptidase family M16) K07263 - - 3.485e-196 622.0
HKD2_k127_3942173_1 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 506.0
HKD2_k127_3942173_10 PFAM MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000002692 190.0
HKD2_k127_3942173_11 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000000006541 182.0
HKD2_k127_3942173_12 - - - - 0.000000000000000000000000000000000000876 142.0
HKD2_k127_3942173_13 Thioesterase K01075 - 3.1.2.23 0.00000000000000000001068 101.0
HKD2_k127_3942173_14 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000006496 68.0
HKD2_k127_3942173_15 PilZ domain - - - 0.00000162 55.0
HKD2_k127_3942173_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 462.0
HKD2_k127_3942173_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 442.0
HKD2_k127_3942173_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 326.0
HKD2_k127_3942173_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 326.0
HKD2_k127_3942173_6 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002652 283.0
HKD2_k127_3942173_7 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003553 263.0
HKD2_k127_3942173_8 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002335 245.0
HKD2_k127_3942173_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000001392 250.0
HKD2_k127_3962802_0 DEAD DEAH box helicase K03724 - - 0.0 1306.0
HKD2_k127_3962802_1 PFAM ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 440.0
HKD2_k127_3962802_10 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000002605 188.0
HKD2_k127_3962802_11 domain, Protein - - - 0.000000000000001211 82.0
HKD2_k127_3962802_12 Recombinase zinc beta ribbon domain - - - 0.00008328 46.0
HKD2_k127_3962802_2 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 437.0
HKD2_k127_3962802_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 387.0
HKD2_k127_3962802_4 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 379.0
HKD2_k127_3962802_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 326.0
HKD2_k127_3962802_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 261.0
HKD2_k127_3962802_7 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006123 258.0
HKD2_k127_3962802_8 - - - - 0.0000000000000000000000000000000000000000000000000000008227 211.0
HKD2_k127_3962802_9 - - - - 0.00000000000000000000000000000000000000000000000000001473 196.0
HKD2_k127_3967450_0 metalloendopeptidase activity K01283 - 3.4.15.1 3.037e-248 801.0
HKD2_k127_3967450_1 PFAM ribonuclease II K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 576.0
HKD2_k127_3967450_2 DNA-templated transcription, initiation K03088,K07263 - - 0.0000000000000000000000000000000000001281 149.0
HKD2_k127_3967450_3 Phosphoglycerate mutase family - - - 0.000000000000000000001167 105.0
HKD2_k127_3969130_0 PFAM ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 315.0
HKD2_k127_3969130_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004672 293.0
HKD2_k127_3969130_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000009081 203.0
HKD2_k127_3969130_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000001083 140.0
HKD2_k127_3969130_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000001473 136.0
HKD2_k127_3969130_5 Trypsin - - - 0.0000001665 58.0
HKD2_k127_3973727_0 PilX N-terminal - - - 0.00003698 56.0
HKD2_k127_4020003_0 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 482.0
HKD2_k127_4020003_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 388.0
HKD2_k127_4020003_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HKD2_k127_4055439_0 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 476.0
HKD2_k127_4055439_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 316.0
HKD2_k127_4055439_10 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000006563 146.0
HKD2_k127_4055439_11 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000002823 129.0
HKD2_k127_4055439_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000136 104.0
HKD2_k127_4055439_13 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000007275 69.0
HKD2_k127_4055439_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009511 298.0
HKD2_k127_4055439_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000002054 229.0
HKD2_k127_4055439_4 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001757 218.0
HKD2_k127_4055439_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000006048 227.0
HKD2_k127_4055439_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000001098 210.0
HKD2_k127_4055439_7 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000007645 184.0
HKD2_k127_4055439_8 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000004803 173.0
HKD2_k127_4055439_9 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000001168 148.0
HKD2_k127_4098727_0 Dehydrogenase E1 component K00162,K11381 - 1.2.4.1,1.2.4.4 4.307e-284 886.0
HKD2_k127_4098727_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.39e-279 868.0
HKD2_k127_4098727_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 415.0
HKD2_k127_4098727_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 384.0
HKD2_k127_4098727_4 Phosphopantetheine attachment site - - - 0.000000000000005419 88.0
HKD2_k127_411650_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 417.0
HKD2_k127_411650_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000002947 201.0
HKD2_k127_411650_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000009174 191.0
HKD2_k127_411650_3 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000002404 132.0
HKD2_k127_411650_4 - - - - 0.000000000000000000000000002128 128.0
HKD2_k127_411650_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000002427 89.0
HKD2_k127_411650_6 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000007712 75.0
HKD2_k127_411650_7 Preprotein translocase SecG subunit K03075 - - 0.00000000000001171 79.0
HKD2_k127_4119489_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.15e-233 733.0
HKD2_k127_4119489_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 499.0
HKD2_k127_4119489_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 479.0
HKD2_k127_4119489_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 469.0
HKD2_k127_4119489_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 461.0
HKD2_k127_4119489_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000003631 88.0
HKD2_k127_4119489_6 Biotin-requiring enzyme - - - 0.00000000000002067 87.0
HKD2_k127_4119489_7 Peptidase M56 - - - 0.00000000003405 75.0
HKD2_k127_4119489_8 gag-polyprotein putative aspartyl protease - - - 0.0001985 54.0
HKD2_k127_4128804_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.157e-244 780.0
HKD2_k127_4128804_1 Peptidase family M13 K07386 - - 8.58e-214 683.0
HKD2_k127_4128804_2 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 511.0
HKD2_k127_4128804_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 407.0
HKD2_k127_4128804_4 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 394.0
HKD2_k127_4128804_5 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000002145 55.0
HKD2_k127_4135661_0 ABC transporter transmembrane region K06147,K18893 - - 2.64e-249 784.0
HKD2_k127_4135661_1 oligopeptide transporter, OPT family - - - 6.179e-216 690.0
HKD2_k127_4135661_10 PFAM peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004867 251.0
HKD2_k127_4135661_11 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004455 252.0
HKD2_k127_4135661_12 PFAM GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000002751 223.0
HKD2_k127_4135661_14 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000001138 214.0
HKD2_k127_4135661_15 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000009024 205.0
HKD2_k127_4135661_16 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000003232 188.0
HKD2_k127_4135661_17 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000004441 179.0
HKD2_k127_4135661_18 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000006578 165.0
HKD2_k127_4135661_19 - - - - 0.00000000000000000000000000000000001232 145.0
HKD2_k127_4135661_2 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 477.0
HKD2_k127_4135661_20 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000005549 145.0
HKD2_k127_4135661_21 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000004709 133.0
HKD2_k127_4135661_22 Peptidase family M1 domain - - - 0.0000000000000000009676 101.0
HKD2_k127_4135661_24 - - - - 0.000007344 53.0
HKD2_k127_4135661_25 Glutaredoxin K03676 - - 0.00001476 48.0
HKD2_k127_4135661_26 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000443 52.0
HKD2_k127_4135661_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 433.0
HKD2_k127_4135661_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 422.0
HKD2_k127_4135661_5 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 410.0
HKD2_k127_4135661_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 314.0
HKD2_k127_4135661_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 323.0
HKD2_k127_4135661_8 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004543 276.0
HKD2_k127_4135661_9 ATP:ADP antiporter activity K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001358 277.0
HKD2_k127_4143924_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 354.0
HKD2_k127_4143924_1 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000131 295.0
HKD2_k127_4143924_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000003359 160.0
HKD2_k127_4143924_3 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000009222 162.0
HKD2_k127_4143924_4 PFAM Radical SAM - - - 0.00000000000000000000000000000001884 129.0
HKD2_k127_4143924_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000001834 116.0
HKD2_k127_4143924_6 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00006061 56.0
HKD2_k127_4144051_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 496.0
HKD2_k127_4144051_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 402.0
HKD2_k127_4144051_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 310.0
HKD2_k127_4144051_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000275 158.0
HKD2_k127_4167024_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 9.258e-270 842.0
HKD2_k127_4167024_1 Radical SAM - - - 1.308e-227 716.0
HKD2_k127_4167024_10 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000002923 62.0
HKD2_k127_4167024_11 Copper resistance protein D K07245 - - 0.0001619 49.0
HKD2_k127_4167024_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 359.0
HKD2_k127_4167024_3 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 333.0
HKD2_k127_4167024_4 YdjC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001016 299.0
HKD2_k127_4167024_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007722 287.0
HKD2_k127_4167024_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001574 267.0
HKD2_k127_4167024_7 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000006046 226.0
HKD2_k127_4167024_8 Histidine kinase K07644,K18351 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004483 220.0
HKD2_k127_4167024_9 membrane - - - 0.0000000000000000000000001126 124.0
HKD2_k127_4169348_0 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 368.0
HKD2_k127_4169348_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000007695 217.0
HKD2_k127_4169348_2 Tellurite resistance protein TerB - - - 0.0000000000216 67.0
HKD2_k127_4185567_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 605.0
HKD2_k127_4185567_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 428.0
HKD2_k127_4202682_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 552.0
HKD2_k127_4202682_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000003681 205.0
HKD2_k127_4202682_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000001812 54.0
HKD2_k127_4202682_3 COGs COG5305 membrane protein - - - 0.0000161 57.0
HKD2_k127_4203093_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.353e-268 842.0
HKD2_k127_4203093_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.295e-213 691.0
HKD2_k127_4203093_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000001348 175.0
HKD2_k127_4203093_11 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000005132 170.0
HKD2_k127_4203093_12 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000001339 170.0
HKD2_k127_4203093_13 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000000000006132 161.0
HKD2_k127_4203093_14 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000009292 164.0
HKD2_k127_4203093_15 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000009145 169.0
HKD2_k127_4203093_16 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000002855 159.0
HKD2_k127_4203093_17 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002022 148.0
HKD2_k127_4203093_18 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000004664 141.0
HKD2_k127_4203093_19 Could be involved in septation K06412 - - 0.000000000000000000000000000004623 123.0
HKD2_k127_4203093_2 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 509.0
HKD2_k127_4203093_20 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000005261 118.0
HKD2_k127_4203093_21 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000002411 115.0
HKD2_k127_4203093_22 Ribosomal protein S18 K02963 - - 0.000000000000000000000009213 109.0
HKD2_k127_4203093_23 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000161 107.0
HKD2_k127_4203093_24 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000001184 87.0
HKD2_k127_4203093_25 heat shock protein binding - - - 0.0000000000000000501 95.0
HKD2_k127_4203093_28 COG1214 Inactive homolog of metal-dependent proteases K01409,K14742 - 2.3.1.234 0.00000000000004068 81.0
HKD2_k127_4203093_29 Domain of unknown function (DUF4126) - - - 0.0000000000006927 82.0
HKD2_k127_4203093_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 482.0
HKD2_k127_4203093_30 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000001456 73.0
HKD2_k127_4203093_31 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000003835 72.0
HKD2_k127_4203093_32 YacP-like NYN domain - - - 0.000000004782 63.0
HKD2_k127_4203093_33 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000665 62.0
HKD2_k127_4203093_34 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000001581 60.0
HKD2_k127_4203093_35 Protein of unknown function (DUF465) - - - 0.0002586 47.0
HKD2_k127_4203093_36 Predicted membrane protein (DUF2232) - - - 0.0005468 51.0
HKD2_k127_4203093_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 417.0
HKD2_k127_4203093_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 339.0
HKD2_k127_4203093_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000005785 233.0
HKD2_k127_4203093_7 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000003077 199.0
HKD2_k127_4203093_8 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000000000001316 183.0
HKD2_k127_4203093_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000007922 172.0
HKD2_k127_4261219_0 lipopolysaccharide transport K22110 - - 0.0 1419.0
HKD2_k127_4261219_1 Amylo-alpha-1,6-glucosidase - - - 6.867e-255 801.0
HKD2_k127_4261219_2 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 537.0
HKD2_k127_4261219_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 514.0
HKD2_k127_4261219_4 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 310.0
HKD2_k127_4261219_5 DoxX-like family K15977 - - 0.00002387 48.0
HKD2_k127_4314006_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.761e-235 752.0
HKD2_k127_4314006_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 308.0
HKD2_k127_4314006_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.0000000000001568 81.0
HKD2_k127_4314006_11 general secretion pathway protein K02456,K02650 - - 0.00000004336 65.0
HKD2_k127_4314006_12 Pilus assembly protein K02662 - - 0.0000001844 63.0
HKD2_k127_4314006_2 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 324.0
HKD2_k127_4314006_3 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000454 308.0
HKD2_k127_4314006_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000004236 197.0
HKD2_k127_4314006_5 domain protein K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000004467 193.0
HKD2_k127_4314006_6 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.0000000000000000000000000000000000000000000000000163 198.0
HKD2_k127_4314006_7 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000008862 178.0
HKD2_k127_4314006_8 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000004991 130.0
HKD2_k127_4314006_9 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000006968 123.0
HKD2_k127_4315085_0 Cysteine-rich domain - - - 1.329e-207 674.0
HKD2_k127_4315085_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
HKD2_k127_4315085_2 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 372.0
HKD2_k127_4315085_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 329.0
HKD2_k127_4315085_4 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000034 229.0
HKD2_k127_4315085_5 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000003752 144.0
HKD2_k127_4315085_6 Belongs to the UPF0102 family K07460 - - 0.000000000000000000003413 98.0
HKD2_k127_433424_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 400.0
HKD2_k127_433424_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000178 291.0
HKD2_k127_433424_10 Bacterial membrane protein YfhO - - - 0.00000000000000006569 96.0
HKD2_k127_433424_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001993 68.0
HKD2_k127_433424_12 positive regulation of growth rate - - - 0.0000000006626 70.0
HKD2_k127_433424_13 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0008692 46.0
HKD2_k127_433424_2 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000001255 230.0
HKD2_k127_433424_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003246 210.0
HKD2_k127_433424_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000006511 161.0
HKD2_k127_433424_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000002141 139.0
HKD2_k127_433424_6 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000001528 134.0
HKD2_k127_433424_7 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000006365 124.0
HKD2_k127_433424_8 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000003256 109.0
HKD2_k127_433424_9 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000003871 93.0
HKD2_k127_4382084_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 617.0
HKD2_k127_4382084_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 559.0
HKD2_k127_4382084_10 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001066 228.0
HKD2_k127_4382084_11 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000006087 224.0
HKD2_k127_4382084_12 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000000009652 214.0
HKD2_k127_4382084_13 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000003436 209.0
HKD2_k127_4382084_14 - - - - 0.000000000000000000000000000000000000000000000000000000001389 204.0
HKD2_k127_4382084_15 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000583 206.0
HKD2_k127_4382084_16 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000006021 197.0
HKD2_k127_4382084_17 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
HKD2_k127_4382084_18 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000652 188.0
HKD2_k127_4382084_19 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000003315 194.0
HKD2_k127_4382084_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 570.0
HKD2_k127_4382084_20 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.0000000000000000000000000000000000000000000001524 181.0
HKD2_k127_4382084_21 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000005164 170.0
HKD2_k127_4382084_22 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000001119 140.0
HKD2_k127_4382084_23 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000001423 129.0
HKD2_k127_4382084_24 Haem-binding domain - - - 0.0000000000000000000000000000117 133.0
HKD2_k127_4382084_25 - - - - 0.0000000000000000000000000001361 123.0
HKD2_k127_4382084_26 acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000001196 130.0
HKD2_k127_4382084_27 enzyme binding K00567,K07443 - 2.1.1.63 0.00000000000000000000000003686 119.0
HKD2_k127_4382084_28 - - - - 0.0000000000000000000001427 109.0
HKD2_k127_4382084_29 - - - - 0.00000000000000000002014 98.0
HKD2_k127_4382084_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 444.0
HKD2_k127_4382084_30 acetyltransferase - - - 0.000000000000007932 82.0
HKD2_k127_4382084_31 acetyltransferase - - - 0.0000000000001142 80.0
HKD2_k127_4382084_32 SpoIIAA-like - - - 0.0000002684 59.0
HKD2_k127_4382084_4 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 359.0
HKD2_k127_4382084_5 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 319.0
HKD2_k127_4382084_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 292.0
HKD2_k127_4382084_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002299 266.0
HKD2_k127_4382084_8 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007354 268.0
HKD2_k127_4382084_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
HKD2_k127_453305_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.756e-313 974.0
HKD2_k127_453305_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 576.0
HKD2_k127_453305_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 291.0
HKD2_k127_453305_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000001979 114.0
HKD2_k127_453305_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000008042 102.0
HKD2_k127_4568118_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 486.0
HKD2_k127_4568118_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003947 259.0
HKD2_k127_4573553_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 2.276e-291 918.0
HKD2_k127_4573553_1 malic protein domain protein K00029 - 1.1.1.40 3.03e-291 912.0
HKD2_k127_4573553_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 498.0
HKD2_k127_4573553_11 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 469.0
HKD2_k127_4573553_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 436.0
HKD2_k127_4573553_13 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 434.0
HKD2_k127_4573553_14 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 393.0
HKD2_k127_4573553_15 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 421.0
HKD2_k127_4573553_16 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 406.0
HKD2_k127_4573553_17 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 376.0
HKD2_k127_4573553_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 363.0
HKD2_k127_4573553_19 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 341.0
HKD2_k127_4573553_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.199e-242 769.0
HKD2_k127_4573553_20 pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 337.0
HKD2_k127_4573553_21 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 345.0
HKD2_k127_4573553_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 331.0
HKD2_k127_4573553_23 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 328.0
HKD2_k127_4573553_24 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 299.0
HKD2_k127_4573553_25 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 286.0
HKD2_k127_4573553_26 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003033 278.0
HKD2_k127_4573553_27 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 274.0
HKD2_k127_4573553_28 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000004773 248.0
HKD2_k127_4573553_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007103 239.0
HKD2_k127_4573553_3 phosphoribosylamine-glycine ligase activity K01945,K01955 - 6.3.4.13,6.3.5.5 4.469e-225 702.0
HKD2_k127_4573553_30 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 245.0
HKD2_k127_4573553_31 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000001886 239.0
HKD2_k127_4573553_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000001208 214.0
HKD2_k127_4573553_33 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001389 214.0
HKD2_k127_4573553_34 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000003109 201.0
HKD2_k127_4573553_35 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000005315 188.0
HKD2_k127_4573553_36 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000002971 184.0
HKD2_k127_4573553_37 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000004059 192.0
HKD2_k127_4573553_38 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000007676 202.0
HKD2_k127_4573553_39 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000008797 179.0
HKD2_k127_4573553_4 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 585.0
HKD2_k127_4573553_40 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000006819 191.0
HKD2_k127_4573553_41 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000007397 166.0
HKD2_k127_4573553_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000001082 157.0
HKD2_k127_4573553_43 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000002285 163.0
HKD2_k127_4573553_44 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000005326 150.0
HKD2_k127_4573553_45 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000001083 164.0
HKD2_k127_4573553_46 HD domain - - - 0.000000000000000000000000000000001422 151.0
HKD2_k127_4573553_47 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000005082 138.0
HKD2_k127_4573553_48 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000009148 130.0
HKD2_k127_4573553_49 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000395 122.0
HKD2_k127_4573553_5 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 585.0
HKD2_k127_4573553_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000002701 114.0
HKD2_k127_4573553_51 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000002841 127.0
HKD2_k127_4573553_53 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity K13939,K13941 GO:0003674,GO:0003824,GO:0003848,GO:0004150,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016772,GO:0016778,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019752,GO:0031967,GO:0031975,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3,4.1.2.25 0.00000000000000000000000001734 120.0
HKD2_k127_4573553_54 LAO AO transport system K07588 - - 0.00000000000000000000000002873 124.0
HKD2_k127_4573553_57 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000001456 115.0
HKD2_k127_4573553_59 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05580 - 1.6.5.3 0.00000000000000000000001231 108.0
HKD2_k127_4573553_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 574.0
HKD2_k127_4573553_61 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000004808 109.0
HKD2_k127_4573553_63 Preprotein translocase subunit K03210 - - 0.000000000000000000005707 97.0
HKD2_k127_4573553_65 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000005986 92.0
HKD2_k127_4573553_67 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000001237 87.0
HKD2_k127_4573553_68 ig-like, plexins, transcription factors - - - 0.000000000000000007663 98.0
HKD2_k127_4573553_7 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 578.0
HKD2_k127_4573553_71 Roadblock/LC7 domain - - - 0.00000000000002363 78.0
HKD2_k127_4573553_73 repeat-containing protein - - - 0.0000000000003977 83.0
HKD2_k127_4573553_74 Protein of unknown function (FYDLN_acid) - - - 0.000000000001491 72.0
HKD2_k127_4573553_75 PFAM Fimbrial assembly family protein K02663 - - 0.0000000002078 72.0
HKD2_k127_4573553_77 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00001001 53.0
HKD2_k127_4573553_78 Tetratricopeptide repeats - - - 0.00001849 57.0
HKD2_k127_4573553_79 Tetratricopeptide repeat - - - 0.0002695 52.0
HKD2_k127_4573553_8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
HKD2_k127_4573553_9 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 571.0
HKD2_k127_4630910_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 474.0
HKD2_k127_4630910_1 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001754 283.0
HKD2_k127_4630910_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000008397 205.0
HKD2_k127_4630910_3 PFAM Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.000000000000000000000000000002401 134.0
HKD2_k127_4630910_4 ECF sigma factor K03088 - - 0.00000000000000000000000022 119.0
HKD2_k127_4630910_5 cytochrome C oxidase K02275 - 1.9.3.1 0.0000000000000004786 89.0
HKD2_k127_4681108_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.596e-265 829.0
HKD2_k127_4681108_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 494.0
HKD2_k127_4681108_10 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000005153 196.0
HKD2_k127_4681108_11 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000177 175.0
HKD2_k127_4681108_12 WYL domain - - - 0.000000000000000000000000000000000000000003421 173.0
HKD2_k127_4681108_13 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000008596 171.0
HKD2_k127_4681108_14 peptidyl-tyrosine sulfation - - - 0.000000000000000000002534 111.0
HKD2_k127_4681108_15 cell redox homeostasis - - - 0.000000000000000000002581 107.0
HKD2_k127_4681108_16 MerR HTH family regulatory protein K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000006694 62.0
HKD2_k127_4681108_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000002501 53.0
HKD2_k127_4681108_18 DoxX K16937 - 1.8.5.2 0.000005201 55.0
HKD2_k127_4681108_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 439.0
HKD2_k127_4681108_3 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 395.0
HKD2_k127_4681108_4 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 390.0
HKD2_k127_4681108_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 375.0
HKD2_k127_4681108_6 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 342.0
HKD2_k127_4681108_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001453 287.0
HKD2_k127_4681108_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001756 264.0
HKD2_k127_4681108_9 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001177 233.0
HKD2_k127_472363_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1266.0
HKD2_k127_472363_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 534.0
HKD2_k127_472363_10 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000965 205.0
HKD2_k127_472363_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000002875 100.0
HKD2_k127_472363_12 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000005776 61.0
HKD2_k127_472363_13 Bacteriophage replication gene A protein (GPA) - - - 0.0000003407 57.0
HKD2_k127_472363_2 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 500.0
HKD2_k127_472363_3 SMART serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 533.0
HKD2_k127_472363_4 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 480.0
HKD2_k127_472363_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 493.0
HKD2_k127_472363_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 377.0
HKD2_k127_472363_7 COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 330.0
HKD2_k127_472363_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001276 318.0
HKD2_k127_472363_9 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000209 221.0
HKD2_k127_4728371_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.743e-235 739.0
HKD2_k127_4728371_1 DNA polymerase beta thumb K02347 - - 1.016e-229 757.0
HKD2_k127_4728371_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000961 114.0
HKD2_k127_4728371_11 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000002208 98.0
HKD2_k127_4728371_12 - - - - 0.0000000000000001117 95.0
HKD2_k127_4728371_13 Thiamine-binding protein - - - 0.000000000000000808 90.0
HKD2_k127_4728371_14 - - - - 0.0000000001383 72.0
HKD2_k127_4728371_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 606.0
HKD2_k127_4728371_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 465.0
HKD2_k127_4728371_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 402.0
HKD2_k127_4728371_5 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 402.0
HKD2_k127_4728371_6 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 347.0
HKD2_k127_4728371_7 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000004171 193.0
HKD2_k127_4728371_8 - - - - 0.0000000000000000000000000000000001949 134.0
HKD2_k127_4728371_9 hyperosmotic response - - - 0.0000000000000000000000000008457 118.0
HKD2_k127_4769_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 8.779e-196 634.0
HKD2_k127_4769_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HKD2_k127_4769_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000005724 177.0
HKD2_k127_4769_3 cytochrome C oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000003576 174.0
HKD2_k127_4769_4 Cytochrome c - - - 0.000000000000000000000000000000000000000465 169.0
HKD2_k127_4769_5 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000004049 143.0
HKD2_k127_4867134_0 Involved in the tonB-independent uptake of proteins - - - 2.715e-207 672.0
HKD2_k127_4867134_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 438.0
HKD2_k127_4867134_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000006654 66.0
HKD2_k127_4972684_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 502.0
HKD2_k127_4972684_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000007846 234.0
HKD2_k127_4972684_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000016 144.0
HKD2_k127_4972684_3 Belongs to the ClpA ClpB family K03696 - - 0.0003641 43.0
HKD2_k127_508541_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 393.0
HKD2_k127_508541_1 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 357.0
HKD2_k127_508541_2 Sigma-70 region 2 - - - 0.000000000000000000000000000000486 124.0
HKD2_k127_508541_3 YCII-related domain - - - 0.00000000000000000003759 95.0
HKD2_k127_508541_4 E-Z type HEAT repeats - - - 0.0000003339 63.0
HKD2_k127_5111227_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 2.264e-196 628.0
HKD2_k127_5111227_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 514.0
HKD2_k127_5111227_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000008858 259.0
HKD2_k127_5111227_11 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
HKD2_k127_5111227_12 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000002 224.0
HKD2_k127_5111227_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
HKD2_k127_5111227_14 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000001253 190.0
HKD2_k127_5111227_15 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000001482 182.0
HKD2_k127_5111227_16 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000001589 184.0
HKD2_k127_5111227_17 Peptidase family M50 - - - 0.000000000000000000000000000000000000000001409 167.0
HKD2_k127_5111227_18 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000001814 169.0
HKD2_k127_5111227_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000004858 165.0
HKD2_k127_5111227_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 464.0
HKD2_k127_5111227_20 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000004298 152.0
HKD2_k127_5111227_21 Urate oxidase N-terminal - - - 0.000000000000000000000000000000001854 148.0
HKD2_k127_5111227_22 histone H2A K63-linked ubiquitination K10914 - - 0.00000000000000000000000000000004077 132.0
HKD2_k127_5111227_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000007615 124.0
HKD2_k127_5111227_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000008606 99.0
HKD2_k127_5111227_25 - - - - 0.00000000000006208 82.0
HKD2_k127_5111227_26 Putative adhesin - - - 0.000001429 62.0
HKD2_k127_5111227_27 HEAT repeats - - - 0.000009253 58.0
HKD2_k127_5111227_28 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000214 55.0
HKD2_k127_5111227_29 Putative adhesin - - - 0.00008915 56.0
HKD2_k127_5111227_3 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 446.0
HKD2_k127_5111227_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 424.0
HKD2_k127_5111227_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 386.0
HKD2_k127_5111227_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 376.0
HKD2_k127_5111227_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
HKD2_k127_5111227_8 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 336.0
HKD2_k127_5111227_9 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
HKD2_k127_5112670_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 368.0
HKD2_k127_5112670_1 Cardiolipin synthetase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 332.0
HKD2_k127_5112670_10 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0005817 44.0
HKD2_k127_5112670_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 295.0
HKD2_k127_5112670_3 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002106 244.0
HKD2_k127_5112670_4 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000003184 197.0
HKD2_k127_5112670_5 TPM domain - - - 0.00000000000000000000000000000000000003468 147.0
HKD2_k127_5112670_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000002402 145.0
HKD2_k127_5112670_7 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000006824 132.0
HKD2_k127_5112670_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000001753 83.0
HKD2_k127_5112670_9 Phosphoglycerate mutase family K08296 - - 0.000000000000003467 81.0
HKD2_k127_5115967_0 TIGRFAM FeS assembly protein SufB K09014 - - 1.937e-265 822.0
HKD2_k127_5115967_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008188 286.0
HKD2_k127_5115967_2 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000001685 241.0
HKD2_k127_5115967_3 Protein of unknown function, DUF393 - - - 0.00000000000004131 74.0
HKD2_k127_5127546_0 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 527.0
HKD2_k127_5127546_1 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 485.0
HKD2_k127_5127546_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000001493 158.0
HKD2_k127_5127546_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000003135 134.0
HKD2_k127_5127546_12 phosphate ion binding K02040 - - 0.00000000000000000000000000001137 123.0
HKD2_k127_5127546_13 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000003014 96.0
HKD2_k127_5127546_14 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000007882 76.0
HKD2_k127_5127546_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 400.0
HKD2_k127_5127546_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 373.0
HKD2_k127_5127546_4 Four helix bundle sensory module for signal transduction K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 359.0
HKD2_k127_5127546_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
HKD2_k127_5127546_6 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 332.0
HKD2_k127_5127546_7 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000003288 189.0
HKD2_k127_5127546_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001171 182.0
HKD2_k127_5127546_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.0000000000000000000000000000000000000003516 158.0
HKD2_k127_5135999_0 aminopeptidase N - - - 0.000000000000000000000000000000000002096 156.0
HKD2_k127_5135999_1 DinB superfamily K07552 - - 0.00000000000000000000000000000000008353 141.0
HKD2_k127_5135999_2 Pirin K06911 - - 0.000000000000000000001377 98.0
HKD2_k127_5135999_3 Heavy-metal resistance - - - 0.000001358 55.0
HKD2_k127_5144132_0 Bacterial protein of unknown function (DUF885) - - - 1.656e-214 681.0
HKD2_k127_5144132_1 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 601.0
HKD2_k127_5144132_10 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000001072 248.0
HKD2_k127_5144132_11 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000000000003394 165.0
HKD2_k127_5144132_12 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000002492 89.0
HKD2_k127_5144132_13 Thioredoxin-like - - - 0.0000002655 59.0
HKD2_k127_5144132_14 - - - - 0.000002355 56.0
HKD2_k127_5144132_2 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 583.0
HKD2_k127_5144132_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 384.0
HKD2_k127_5144132_4 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 368.0
HKD2_k127_5144132_5 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 358.0
HKD2_k127_5144132_6 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 339.0
HKD2_k127_5144132_7 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 322.0
HKD2_k127_5144132_8 4-hydroxyproline epimerase activity K01777,K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.4,5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 333.0
HKD2_k127_5144132_9 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002164 247.0
HKD2_k127_5158975_1 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000004603 155.0
HKD2_k127_5188480_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.561e-277 874.0
HKD2_k127_5188480_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 621.0
HKD2_k127_5188480_10 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000004263 124.0
HKD2_k127_5188480_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000007154 110.0
HKD2_k127_5188480_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000001363 105.0
HKD2_k127_5188480_13 Polymer-forming cytoskeletal - - - 0.0000000000000000000002983 102.0
HKD2_k127_5188480_14 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000003405 94.0
HKD2_k127_5188480_15 Ribosomal protein L34 K02914 - - 0.000000000000005421 75.0
HKD2_k127_5188480_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000262 72.0
HKD2_k127_5188480_17 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000001513 64.0
HKD2_k127_5188480_18 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0002504 53.0
HKD2_k127_5188480_19 ATP synthase B/B' CF(0) K02109 - - 0.0008269 51.0
HKD2_k127_5188480_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 435.0
HKD2_k127_5188480_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 359.0
HKD2_k127_5188480_4 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
HKD2_k127_5188480_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 323.0
HKD2_k127_5188480_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007752 285.0
HKD2_k127_5188480_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003489 264.0
HKD2_k127_5188480_8 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000007366 215.0
HKD2_k127_5188480_9 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000001604 227.0
HKD2_k127_5191867_0 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 465.0
HKD2_k127_5191867_1 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 465.0
HKD2_k127_5191867_2 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 335.0
HKD2_k127_5191867_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000003374 191.0
HKD2_k127_5191867_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000004004 192.0
HKD2_k127_5264037_0 Protein export membrane protein K03296,K18138 - - 0.0 1265.0
HKD2_k127_5264037_1 Sulfate permease family - - - 6.911e-228 721.0
HKD2_k127_5264037_10 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 460.0
HKD2_k127_5264037_11 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
HKD2_k127_5264037_12 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
HKD2_k127_5264037_13 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 375.0
HKD2_k127_5264037_14 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 337.0
HKD2_k127_5264037_15 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005369 276.0
HKD2_k127_5264037_16 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
HKD2_k127_5264037_17 helix_turn_helix, Lux Regulon K11712,K14987 - - 0.00000000000000000000000000000000000000000000000009776 203.0
HKD2_k127_5264037_19 response regulator receiver K13041 - - 0.000000000000000000000000000002609 124.0
HKD2_k127_5264037_2 regulation of DNA-templated transcription, elongation - - - 1.739e-211 687.0
HKD2_k127_5264037_20 - - - - 0.00000000000000000007903 104.0
HKD2_k127_5264037_3 Fumarase C C-terminus K01744 - 4.3.1.1 6.463e-207 681.0
HKD2_k127_5264037_4 Predicted Permease Membrane Region K07085 - - 3.229e-195 646.0
HKD2_k127_5264037_5 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 508.0
HKD2_k127_5264037_6 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 458.0
HKD2_k127_5264037_7 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 441.0
HKD2_k127_5264037_8 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 445.0
HKD2_k127_5264037_9 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 449.0
HKD2_k127_5267379_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 1.968e-277 879.0
HKD2_k127_5267379_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 528.0
HKD2_k127_5267379_10 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000001253 137.0
HKD2_k127_5267379_11 Thioredoxin-like - - - 0.00000000000000000000000007915 123.0
HKD2_k127_5267379_12 Thioredoxin-like - - - 0.0000000000000000000000001187 114.0
HKD2_k127_5267379_13 protein histidine kinase activity K06375 - - 0.0000000000000000000003536 105.0
HKD2_k127_5267379_14 by modhmm - - - 0.000000000000000989 89.0
HKD2_k127_5267379_17 protein-disulfide reductase activity K04084 - 1.8.1.8 0.0000000000001113 78.0
HKD2_k127_5267379_18 Beta-lactamase - - - 0.0000000002568 74.0
HKD2_k127_5267379_19 - - - - 0.000000005445 68.0
HKD2_k127_5267379_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 484.0
HKD2_k127_5267379_20 Copper binding proteins, plastocyanin/azurin family - - - 0.0000002523 62.0
HKD2_k127_5267379_3 PFAM Cytochrome b b6 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 400.0
HKD2_k127_5267379_4 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 383.0
HKD2_k127_5267379_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001092 286.0
HKD2_k127_5267379_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007264 261.0
HKD2_k127_5267379_7 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000008457 233.0
HKD2_k127_5267379_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000005328 213.0
HKD2_k127_5267379_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000001231 198.0
HKD2_k127_5286844_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009962 259.0
HKD2_k127_5286844_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000001401 121.0
HKD2_k127_5295515_0 Involved in the tonB-independent uptake of proteins - - - 8.438e-195 635.0
HKD2_k127_5295515_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000002257 68.0
HKD2_k127_5338568_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1110.0
HKD2_k127_5338568_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.811e-260 815.0
HKD2_k127_5338568_10 - - - - 0.000000000000000000000000000000000000000000000000001687 210.0
HKD2_k127_5338568_11 Histidine kinase - - - 0.000000000000000000000000000000000000000002605 170.0
HKD2_k127_5338568_12 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000007087 171.0
HKD2_k127_5338568_13 Tautomerase enzyme - - - 0.0000000000000000000000000000000000000008119 153.0
HKD2_k127_5338568_14 DinB family - - - 0.000000000000000000000000000000000001905 145.0
HKD2_k127_5338568_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000007747 136.0
HKD2_k127_5338568_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000004303 117.0
HKD2_k127_5338568_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000005728 97.0
HKD2_k127_5338568_18 YbbR-like protein - - - 0.00000000000000007325 92.0
HKD2_k127_5338568_19 PFAM Outer membrane efflux protein - - - 0.0000000000000001372 93.0
HKD2_k127_5338568_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 604.0
HKD2_k127_5338568_20 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000001535 93.0
HKD2_k127_5338568_21 Sulfurtransferase - - - 0.000000000000003595 91.0
HKD2_k127_5338568_3 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 365.0
HKD2_k127_5338568_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 324.0
HKD2_k127_5338568_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000001816 241.0
HKD2_k127_5338568_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000003485 231.0
HKD2_k127_5338568_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000017 202.0
HKD2_k127_5338568_8 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000001314 211.0
HKD2_k127_5338568_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000004419 209.0
HKD2_k127_5346869_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 540.0
HKD2_k127_5346869_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000024 79.0
HKD2_k127_5353275_0 Prolyl oligopeptidase K01322 - 3.4.21.26 2.7e-239 761.0
HKD2_k127_5353275_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000007708 214.0
HKD2_k127_5353275_2 DinB superfamily - - - 0.0000000000000000000000000000001276 140.0
HKD2_k127_5353275_3 DinB family - - - 0.0000000000000000000000000000004652 130.0
HKD2_k127_5353275_4 Putative serine dehydratase domain - - - 0.00000000000000000000002184 104.0
HKD2_k127_5353275_5 PAP2 superfamily K19302 - 3.6.1.27 0.0000000000000000000006068 104.0
HKD2_k127_5353275_6 collagen metabolic process - - - 0.000000002371 66.0
HKD2_k127_5451524_0 ABC transporter K06020 - 3.6.3.25 2.653e-262 817.0
HKD2_k127_5451524_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 289.0
HKD2_k127_5451524_2 Beta-lactamase superfamily domain K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002932 268.0
HKD2_k127_5451524_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006283 265.0
HKD2_k127_5451524_4 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
HKD2_k127_5451524_5 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000002137 244.0
HKD2_k127_5451524_6 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000004824 229.0
HKD2_k127_5451524_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000004246 209.0
HKD2_k127_5451524_8 Protein of unknown function (DUF983) - - - 0.00000000003704 70.0
HKD2_k127_5451524_9 salt-induced outer membrane protein K07283 - - 0.0000008934 60.0
HKD2_k127_5495884_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.65e-198 649.0
HKD2_k127_5495884_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 526.0
HKD2_k127_5495884_10 YGGT family K02221 - - 0.0000000000000005607 89.0
HKD2_k127_5495884_11 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00006085 53.0
HKD2_k127_5495884_2 Elongation factor SelB winged helix 3 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 447.0
HKD2_k127_5495884_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 365.0
HKD2_k127_5495884_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000972 213.0
HKD2_k127_5495884_5 YqeY-like protein K09117 - - 0.000000000000000000000000000000003131 133.0
HKD2_k127_5495884_6 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000003446 125.0
HKD2_k127_5495884_7 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000005761 137.0
HKD2_k127_5495884_8 DivIVA protein K04074 - - 0.0000000000000000634 87.0
HKD2_k127_5495884_9 C4-type zinc ribbon domain K07164 - - 0.0000000000000002912 88.0
HKD2_k127_5508693_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 522.0
HKD2_k127_5508693_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000002318 196.0
HKD2_k127_5508693_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000006841 198.0
HKD2_k127_5508693_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000008321 192.0
HKD2_k127_5508693_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001915 181.0
HKD2_k127_5508693_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000015 177.0
HKD2_k127_5508693_6 DSBA-like thioredoxin domain - - - 0.00000000000000005486 93.0
HKD2_k127_5508693_7 Peptidase M56 - - - 0.00000000002867 75.0
HKD2_k127_5508693_8 Thioredoxin - - - 0.0000001083 64.0
HKD2_k127_5522011_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 583.0
HKD2_k127_5603824_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 381.0
HKD2_k127_5603824_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 295.0
HKD2_k127_5603824_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000001172 158.0
HKD2_k127_5603824_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.000000000000000000000002898 106.0
HKD2_k127_5627234_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 508.0
HKD2_k127_5627234_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 512.0
HKD2_k127_5627234_10 - - - - 0.000001502 62.0
HKD2_k127_5627234_11 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000209 51.0
HKD2_k127_5627234_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 520.0
HKD2_k127_5627234_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 407.0
HKD2_k127_5627234_4 Formyl transferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005359 289.0
HKD2_k127_5627234_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008992 278.0
HKD2_k127_5627234_6 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000003037 179.0
HKD2_k127_5627234_8 - - - - 0.00000000000000000000000000001317 138.0
HKD2_k127_5627234_9 Bacterial membrane protein YfhO - - - 0.000000000007547 79.0
HKD2_k127_563987_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 348.0
HKD2_k127_563987_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 346.0
HKD2_k127_563987_2 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000006873 143.0
HKD2_k127_563987_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000003358 89.0
HKD2_k127_563987_4 TIGRFAM TonB family C-terminal domain K03832 - - 0.000004985 59.0
HKD2_k127_5677158_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.621e-201 647.0
HKD2_k127_5677158_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000003551 117.0
HKD2_k127_5677158_2 Sigma-70 region 2 K03088 - - 0.000000000000003712 88.0
HKD2_k127_5677158_3 LTXXQ motif family protein K06006 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051082,GO:0061077,GO:1990507 - 0.000001692 57.0
HKD2_k127_569766_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 1.045e-295 925.0
HKD2_k127_569766_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 603.0
HKD2_k127_569766_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000002473 104.0
HKD2_k127_569766_11 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000001048 94.0
HKD2_k127_569766_12 Putative phosphatase (DUF442) - - - 0.000000000001575 76.0
HKD2_k127_569766_13 ATPase activity, coupled to transmembrane movement of substances K02120 - - 0.000000000005593 74.0
HKD2_k127_569766_14 - - - - 0.000000000155 76.0
HKD2_k127_569766_15 PFAM Outer membrane efflux protein - - - 0.000000002113 70.0
HKD2_k127_569766_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0006094 51.0
HKD2_k127_569766_2 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 555.0
HKD2_k127_569766_3 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 498.0
HKD2_k127_569766_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 417.0
HKD2_k127_569766_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 404.0
HKD2_k127_569766_6 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 351.0
HKD2_k127_569766_7 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 341.0
HKD2_k127_569766_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 274.0
HKD2_k127_569766_9 PFAM Hly-III family protein K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
HKD2_k127_5704301_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.593e-201 646.0
HKD2_k127_5704301_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 526.0
HKD2_k127_5704301_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000005606 177.0
HKD2_k127_5704301_11 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000005682 187.0
HKD2_k127_5704301_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000003149 160.0
HKD2_k127_5704301_13 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000005641 153.0
HKD2_k127_5704301_14 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000002355 117.0
HKD2_k127_5704301_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000005537 103.0
HKD2_k127_5704301_16 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000001826 98.0
HKD2_k127_5704301_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000001208 107.0
HKD2_k127_5704301_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000001363 94.0
HKD2_k127_5704301_19 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000523 87.0
HKD2_k127_5704301_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 492.0
HKD2_k127_5704301_20 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000005292 87.0
HKD2_k127_5704301_21 - - - - 0.00000002541 65.0
HKD2_k127_5704301_22 - - - - 0.00000004904 65.0
HKD2_k127_5704301_23 Sigma-70, region 4 - - - 0.0001486 49.0
HKD2_k127_5704301_24 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.0003803 51.0
HKD2_k127_5704301_25 AfsR family transcriptional regulator - - - 0.0004028 53.0
HKD2_k127_5704301_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 477.0
HKD2_k127_5704301_4 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 349.0
HKD2_k127_5704301_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 318.0
HKD2_k127_5704301_6 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 329.0
HKD2_k127_5704301_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 281.0
HKD2_k127_5704301_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001828 248.0
HKD2_k127_5704301_9 polysaccharide deactylase family protein - - - 0.0000000000000000000000000000000000000000000000003002 188.0
HKD2_k127_5717028_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1344.0
HKD2_k127_5717028_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 448.0
HKD2_k127_5717028_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 326.0
HKD2_k127_5717028_3 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000005266 165.0
HKD2_k127_5717028_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001382 140.0
HKD2_k127_573_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 521.0
HKD2_k127_573_1 Putative lumazine-binding - - - 0.00000000000000000000001278 106.0
HKD2_k127_5746721_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 603.0
HKD2_k127_5746721_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000005091 274.0
HKD2_k127_5746721_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001872 67.0
HKD2_k127_5746721_11 ribosomal protein l30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000001766 68.0
HKD2_k127_5746721_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008839 212.0
HKD2_k127_5746721_3 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003387 205.0
HKD2_k127_5746721_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000007908 205.0
HKD2_k127_5746721_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000003285 181.0
HKD2_k127_5746721_6 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000653 165.0
HKD2_k127_5746721_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000121 156.0
HKD2_k127_5746721_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000002258 140.0
HKD2_k127_5746721_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000001405 135.0
HKD2_k127_5761535_0 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 388.0
HKD2_k127_5761535_1 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.000000000000000000000005629 119.0
HKD2_k127_5761535_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0001018 47.0
HKD2_k127_585018_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.168e-287 904.0
HKD2_k127_585018_1 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 511.0
HKD2_k127_585018_10 PFAM Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000021 288.0
HKD2_k127_585018_11 ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004103 269.0
HKD2_k127_585018_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000003707 226.0
HKD2_k127_585018_13 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000000000000000122 230.0
HKD2_k127_585018_14 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000000001434 201.0
HKD2_k127_585018_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000009652 198.0
HKD2_k127_585018_16 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000002033 186.0
HKD2_k127_585018_17 HemY domain protein - - - 0.00000000000000000000000000000000000000003708 177.0
HKD2_k127_585018_18 Peptidase family M23 - - - 0.0000000000000000000000000000000000000007279 160.0
HKD2_k127_585018_19 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000003695 167.0
HKD2_k127_585018_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 531.0
HKD2_k127_585018_20 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000001535 145.0
HKD2_k127_585018_21 endo-1,4-beta-xylanase activity - GO:0005575,GO:0005576 - 0.00000000000000000000003202 113.0
HKD2_k127_585018_22 Domain of unknown function (DUF4439) - - - 0.000000000000000000002426 106.0
HKD2_k127_585018_23 Diguanylate cyclase - - - 0.00000000000000000001628 104.0
HKD2_k127_585018_24 Anti-sigma-K factor rskA - - - 0.00000000000000000002356 100.0
HKD2_k127_585018_25 Smr domain - - - 0.0000000000000000003608 94.0
HKD2_k127_585018_26 Iron-binding zinc finger CDGSH type K05710 - - 0.00000000000000287 78.0
HKD2_k127_585018_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 481.0
HKD2_k127_585018_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 472.0
HKD2_k127_585018_5 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 471.0
HKD2_k127_585018_6 PFAM Na-Ca exchanger integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 420.0
HKD2_k127_585018_7 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 323.0
HKD2_k127_585018_8 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 307.0
HKD2_k127_585018_9 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004145 283.0
HKD2_k127_5977360_0 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 312.0
HKD2_k127_5977360_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000007862 126.0
HKD2_k127_5977360_2 Signal peptide protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00000000000508 75.0
HKD2_k127_5993632_0 Sulfatase K01130 - 3.1.6.1 0.0 1349.0
HKD2_k127_5993632_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 7.021e-212 679.0
HKD2_k127_5993632_10 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000007615 220.0
HKD2_k127_5993632_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000003071 187.0
HKD2_k127_5993632_12 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000004132 187.0
HKD2_k127_5993632_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000007315 189.0
HKD2_k127_5993632_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000001718 181.0
HKD2_k127_5993632_15 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000000000009382 163.0
HKD2_k127_5993632_16 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000005989 147.0
HKD2_k127_5993632_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000687 140.0
HKD2_k127_5993632_18 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000002537 130.0
HKD2_k127_5993632_19 O-Antigen ligase K18814 - - 0.00000000000000000000000000008034 130.0
HKD2_k127_5993632_2 mRNA catabolic process K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 548.0
HKD2_k127_5993632_20 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002559 87.0
HKD2_k127_5993632_21 Redoxin K03564 - 1.11.1.15 0.0000000000002814 71.0
HKD2_k127_5993632_22 Redoxin K03564 - 1.11.1.15 0.00000000001364 68.0
HKD2_k127_5993632_23 Cell division protein ZapA K09888 - - 0.00000000002181 68.0
HKD2_k127_5993632_24 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000008309 75.0
HKD2_k127_5993632_25 Belongs to the UPF0434 family K09791 - - 0.000000002033 62.0
HKD2_k127_5993632_3 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 452.0
HKD2_k127_5993632_4 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 398.0
HKD2_k127_5993632_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 363.0
HKD2_k127_5993632_6 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
HKD2_k127_5993632_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 309.0
HKD2_k127_5993632_8 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000429 283.0
HKD2_k127_5993632_9 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000008315 242.0
HKD2_k127_6386937_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 3.835e-222 705.0
HKD2_k127_6386937_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 529.0
HKD2_k127_6386937_2 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 432.0
HKD2_k127_6386937_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005128 294.0
HKD2_k127_6386937_4 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000002525 262.0
HKD2_k127_6386937_5 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002346 192.0
HKD2_k127_6386937_6 - - - - 0.0000000000000000000000007481 118.0
HKD2_k127_6386937_7 Sporulation and spore germination - - - 0.0000000000005474 83.0
HKD2_k127_6388244_0 MacB-like periplasmic core domain - - - 1.781e-229 734.0
HKD2_k127_6388244_1 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000001576 167.0
HKD2_k127_6405201_0 WD40-like Beta Propeller Repeat - - - 5.657e-238 762.0
HKD2_k127_6405201_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 263.0
HKD2_k127_6409965_0 peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 542.0
HKD2_k127_6409965_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 447.0
HKD2_k127_6409965_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 451.0
HKD2_k127_6409965_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003528 285.0
HKD2_k127_6409965_4 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000006547 214.0
HKD2_k127_6409965_5 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000001023 79.0
HKD2_k127_6417827_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 523.0
HKD2_k127_6417827_1 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 366.0
HKD2_k127_6417827_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000003155 151.0
HKD2_k127_6417827_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 333.0
HKD2_k127_6417827_3 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 320.0
HKD2_k127_6417827_4 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 300.0
HKD2_k127_6417827_5 metallochaperone-like domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006385 280.0
HKD2_k127_6417827_6 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000001455 244.0
HKD2_k127_6417827_7 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000213 246.0
HKD2_k127_6417827_8 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K00087,K07402 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000013 208.0
HKD2_k127_6417827_9 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000001403 175.0
HKD2_k127_6439062_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 481.0
HKD2_k127_6439062_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 417.0
HKD2_k127_6439062_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000004303 200.0
HKD2_k127_6439062_11 Thioesterase superfamily K18014 - 4.3.1.14 0.000000000000000000000000000000000000000002403 169.0
HKD2_k127_6439062_12 transglycosylase K08309 - - 0.000000000000000000000000000000000492 151.0
HKD2_k127_6439062_2 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 388.0
HKD2_k127_6439062_3 amino acid K03294,K13868 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 354.0
HKD2_k127_6439062_4 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 328.0
HKD2_k127_6439062_5 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 314.0
HKD2_k127_6439062_6 Tyrosine recombinase xerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002909 284.0
HKD2_k127_6439062_7 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
HKD2_k127_6439062_8 B12 binding domain K18011 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
HKD2_k127_6439062_9 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002904 242.0
HKD2_k127_6494971_0 Por secretion system C-terminal sorting domain-containing protein - - - 0.000000000000009169 88.0
HKD2_k127_6513210_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 424.0
HKD2_k127_6513210_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 372.0
HKD2_k127_6513210_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000006786 233.0
HKD2_k127_6513210_3 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000001278 200.0
HKD2_k127_6513210_4 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000001853 195.0
HKD2_k127_6513210_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000259 133.0
HKD2_k127_6513210_6 PFAM NHL repeat containing protein - - - 0.0000000000000000000000002259 118.0
HKD2_k127_6515575_0 ABC transporter, transmembrane K11085 - - 9.457e-206 660.0
HKD2_k127_6515575_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 502.0
HKD2_k127_6515575_10 high-affinity ferrous iron transmembrane transporter activity K07243 - - 0.0000000000000000000000000000000001879 145.0
HKD2_k127_6515575_11 Helix-turn-helix domain - - - 0.00000000000000000000000000000002213 133.0
HKD2_k127_6515575_12 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000002793 142.0
HKD2_k127_6515575_15 - - - - 0.000000000000001995 87.0
HKD2_k127_6515575_17 PFAM blue (type 1) copper domain protein - - - 0.000000005943 63.0
HKD2_k127_6515575_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 430.0
HKD2_k127_6515575_3 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 340.0
HKD2_k127_6515575_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 259.0
HKD2_k127_6515575_5 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000788 226.0
HKD2_k127_6515575_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000002676 196.0
HKD2_k127_6515575_7 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000001451 172.0
HKD2_k127_6515575_8 photosynthesis - - - 0.000000000000000000000000000000000000000009812 165.0
HKD2_k127_6515575_9 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002315 144.0
HKD2_k127_6529388_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 256.0
HKD2_k127_6529388_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000002836 202.0
HKD2_k127_6529388_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.000000004708 68.0
HKD2_k127_6529388_11 - - - - 0.0000001051 61.0
HKD2_k127_6529388_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000003458 193.0
HKD2_k127_6529388_3 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000005139 177.0
HKD2_k127_6529388_4 - - - - 0.0000000000000000000000000000000000000000005583 176.0
HKD2_k127_6529388_5 - - - - 0.000000000000000000000000000008235 122.0
HKD2_k127_6529388_6 - - - - 0.0000000000000000000000000002829 117.0
HKD2_k127_6529388_7 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000007237 99.0
HKD2_k127_6529388_8 Phospholipid methyltransferase - - - 0.000000000000000001643 95.0
HKD2_k127_6529388_9 PFAM Methyltransferase domain - - - 0.00000000000000556 84.0
HKD2_k127_6571585_0 Belongs to the ribulokinase family K00853 - 2.7.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 445.0
HKD2_k127_6571585_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000001153 142.0
HKD2_k127_6579021_0 Involved in the tonB-independent uptake of proteins - - - 1.773e-226 733.0
HKD2_k127_6579021_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 479.0
HKD2_k127_6579021_10 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000003323 203.0
HKD2_k127_6579021_11 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000007032 181.0
HKD2_k127_6579021_12 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000009289 137.0
HKD2_k127_6579021_13 - - - - 0.000000000000000000000000002113 122.0
HKD2_k127_6579021_14 RNA recognition motif - - - 0.0000000000000000000000001922 109.0
HKD2_k127_6579021_15 Dodecin K09165 - - 0.00000000000000000000006486 107.0
HKD2_k127_6579021_16 Lysin motif - - - 0.00000000000000000003153 93.0
HKD2_k127_6579021_17 - - - - 0.0000000000000000217 89.0
HKD2_k127_6579021_18 Protein of unknown function (DUF3617) - - - 0.00001508 53.0
HKD2_k127_6579021_19 SnoaL-like polyketide cyclase - - - 0.00001992 49.0
HKD2_k127_6579021_2 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 477.0
HKD2_k127_6579021_20 - - - - 0.00004166 50.0
HKD2_k127_6579021_22 UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 - 2.5.1.7 0.0007477 48.0
HKD2_k127_6579021_23 Putative zinc-finger - - - 0.0009642 46.0
HKD2_k127_6579021_3 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 394.0
HKD2_k127_6579021_4 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
HKD2_k127_6579021_5 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 381.0
HKD2_k127_6579021_6 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
HKD2_k127_6579021_7 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 352.0
HKD2_k127_6579021_8 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 281.0
HKD2_k127_6579021_9 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000002186 214.0
HKD2_k127_6611019_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 441.0
HKD2_k127_6611019_1 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 421.0
HKD2_k127_6611019_10 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000001023 225.0
HKD2_k127_6611019_11 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000004462 182.0
HKD2_k127_6611019_12 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000001971 151.0
HKD2_k127_6611019_13 Phosphate-selective porin O and P - - - 0.0000000000000000000000001642 123.0
HKD2_k127_6611019_14 CHAD - - - 0.00000008175 63.0
HKD2_k127_6611019_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 449.0
HKD2_k127_6611019_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 411.0
HKD2_k127_6611019_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 375.0
HKD2_k127_6611019_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 341.0
HKD2_k127_6611019_6 catalyzes the methylation of cytosine at position 1962 of the 23S rRNA K06969 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 305.0
HKD2_k127_6611019_7 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006987 298.0
HKD2_k127_6611019_8 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004361 271.0
HKD2_k127_6611019_9 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000002615 213.0
HKD2_k127_6621304_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 595.0
HKD2_k127_6621304_1 Methyltransferase domain - - - 0.0000000000000000000009378 100.0
HKD2_k127_6621304_2 Phospholipase_D-nuclease N-terminal - - - 0.000000006103 63.0
HKD2_k127_6625908_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 574.0
HKD2_k127_6625908_1 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000005891 293.0
HKD2_k127_6625908_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001725 265.0
HKD2_k127_6625908_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000003741 114.0
HKD2_k127_6625908_4 Peptidase M56 K03646 - - 0.0000000005957 71.0
HKD2_k127_663424_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.335e-265 835.0
HKD2_k127_663424_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000009517 258.0
HKD2_k127_6639248_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 383.0
HKD2_k127_6639248_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000004536 158.0
HKD2_k127_6639248_2 queuosine biosynthesis protein QueD K01737 - 4.1.2.50,4.2.3.12 0.000000000000009825 78.0
HKD2_k127_6639429_0 Protein kinase domain K12132 - 2.7.11.1 4.428e-238 765.0
HKD2_k127_6639429_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 1.78e-229 735.0
HKD2_k127_6639429_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000004706 170.0
HKD2_k127_6639429_3 - - - - 0.000000000000000000006799 94.0
HKD2_k127_6639468_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 617.0
HKD2_k127_6639468_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000003286 237.0
HKD2_k127_6654001_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.1e-322 1003.0
HKD2_k127_6654001_1 COGs COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000003584 208.0
HKD2_k127_6654001_2 carbon monoxide dehydrogenase K03518 - 1.2.5.3 0.00000000000159 67.0
HKD2_k127_6668449_0 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003306 263.0
HKD2_k127_6668449_1 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000004342 171.0
HKD2_k127_6668449_3 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000004861 132.0
HKD2_k127_6668449_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000003058 106.0
HKD2_k127_6668449_5 Outer membrane protein beta-barrel domain K16079 - - 0.000005453 57.0
HKD2_k127_6688899_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.026e-208 659.0
HKD2_k127_6688899_1 outer membrane efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 350.0
HKD2_k127_6688899_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005441 279.0
HKD2_k127_6698696_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 468.0
HKD2_k127_6698696_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 398.0
HKD2_k127_6698696_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 321.0
HKD2_k127_6698696_3 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 301.0
HKD2_k127_6698696_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000187 265.0
HKD2_k127_6698696_5 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000002296 133.0
HKD2_k127_6698696_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000001004 115.0
HKD2_k127_6698696_7 Phosphoribosyl transferase domain - - - 0.000000000000000000000009068 111.0
HKD2_k127_6717026_0 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
HKD2_k127_6717026_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 352.0
HKD2_k127_6717026_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000001528 217.0
HKD2_k127_6717026_3 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000486 171.0
HKD2_k127_6717026_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000007206 170.0
HKD2_k127_6717026_5 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000005558 126.0
HKD2_k127_6717026_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000006745 109.0
HKD2_k127_6772181_0 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 411.0
HKD2_k127_6772181_1 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 372.0
HKD2_k127_6772181_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 361.0
HKD2_k127_6772181_3 Cytochrome C oxidase, cbb3-type, subunit III K19713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016669,GO:0050338,GO:0055114 1.8.2.2 0.0000000000000000000000000000000000000006692 159.0
HKD2_k127_6772181_4 Putative DNA-binding domain - - - 0.00000000000000000002251 103.0
HKD2_k127_6772181_5 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000001495 74.0
HKD2_k127_6772181_6 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000001973 53.0
HKD2_k127_6772181_7 PFAM sigma-70 region 2 domain protein K03088 - - 0.000002599 50.0
HKD2_k127_6772181_8 - - - - 0.0005558 48.0
HKD2_k127_6788580_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.382e-207 655.0
HKD2_k127_6788580_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 493.0
HKD2_k127_6871667_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 520.0
HKD2_k127_6871667_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HKD2_k127_6871667_2 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD2_k127_6871667_3 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000005337 96.0
HKD2_k127_6871667_4 Domain of Unknown Function (DUF1080) - - - 0.0000002047 62.0
HKD2_k127_6884244_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1447.0
HKD2_k127_6884244_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 6.004e-229 722.0
HKD2_k127_6884244_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 330.0
HKD2_k127_6884244_11 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 321.0
HKD2_k127_6884244_12 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 263.0
HKD2_k127_6884244_13 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001008 251.0
HKD2_k127_6884244_14 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000623 261.0
HKD2_k127_6884244_15 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000006595 227.0
HKD2_k127_6884244_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 230.0
HKD2_k127_6884244_17 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000008185 225.0
HKD2_k127_6884244_18 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001358 223.0
HKD2_k127_6884244_19 Beta-lactamase class C and other penicillin binding - - - 0.0000000000000000000000000000000000000000000000004195 201.0
HKD2_k127_6884244_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 646.0
HKD2_k127_6884244_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000793 198.0
HKD2_k127_6884244_21 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000002472 175.0
HKD2_k127_6884244_22 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000001797 187.0
HKD2_k127_6884244_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001578 168.0
HKD2_k127_6884244_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000001916 156.0
HKD2_k127_6884244_25 TOBE domain - - - 0.0000000000000000000000000000006786 126.0
HKD2_k127_6884244_26 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000523 133.0
HKD2_k127_6884244_27 Histidine kinase - - - 0.00000000000000000000000000001886 133.0
HKD2_k127_6884244_28 PFAM membrane-bound metal-dependent hydrolase K07038 - - 0.000000000000000000000000001913 125.0
HKD2_k127_6884244_29 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000003023 123.0
HKD2_k127_6884244_3 Transposase K02557,K07484,K13924,K21471 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 593.0
HKD2_k127_6884244_30 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000001385 100.0
HKD2_k127_6884244_31 Thioesterase-like superfamily K07107 - - 0.000000000000000002706 93.0
HKD2_k127_6884244_32 Iron-sulfur cluster-binding domain - - - 0.00000000000000003568 95.0
HKD2_k127_6884244_33 Putative MetA-pathway of phenol degradation - - - 0.000000000000001142 88.0
HKD2_k127_6884244_34 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000001412 79.0
HKD2_k127_6884244_35 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001118 63.0
HKD2_k127_6884244_36 - - - - 0.00009173 56.0
HKD2_k127_6884244_37 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0006272 51.0
HKD2_k127_6884244_4 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 505.0
HKD2_k127_6884244_5 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 405.0
HKD2_k127_6884244_6 outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 385.0
HKD2_k127_6884244_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 355.0
HKD2_k127_6884244_8 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 352.0
HKD2_k127_6884244_9 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 323.0
HKD2_k127_6888092_0 E1-E2 ATPase K01535 - 3.6.3.6 2.185e-281 887.0
HKD2_k127_6888092_1 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000619 145.0
HKD2_k127_6888092_2 Thioesterase superfamily - - - 0.0000000000000000000000000000001086 130.0
HKD2_k127_6888092_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000001757 87.0
HKD2_k127_6888092_6 PFAM Polyketide cyclase dehydrase - - - 0.000001035 63.0
HKD2_k127_6890488_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
HKD2_k127_6890488_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000003658 220.0
HKD2_k127_6890488_2 Tricorn protease C1 domain K03797 - 3.4.21.102 0.0000000000000000000001545 111.0
HKD2_k127_6890488_3 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000001424 73.0
HKD2_k127_6921356_0 Extracellular solute-binding protein K02027 - - 1.293e-218 682.0
HKD2_k127_6921356_1 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 452.0
HKD2_k127_6921356_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 432.0
HKD2_k127_6921356_3 Binding-protein-dependent transport system inner membrane component K02025,K10118,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 430.0
HKD2_k127_6980645_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 600.0
HKD2_k127_6980645_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 466.0
HKD2_k127_7077935_0 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
HKD2_k127_7077935_1 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000001168 160.0
HKD2_k127_7156676_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1084.0
HKD2_k127_7156676_1 Dehydrogenase E1 component K11381 - 1.2.4.4 1e-323 1002.0
HKD2_k127_7156676_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000006088 214.0
HKD2_k127_7156676_11 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000121 213.0
HKD2_k127_7156676_12 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000003344 191.0
HKD2_k127_7156676_13 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000002471 198.0
HKD2_k127_7156676_14 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000000000000000000000000003046 169.0
HKD2_k127_7156676_15 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000002851 153.0
HKD2_k127_7156676_16 - - - - 0.0000000000000000000000000000006377 127.0
HKD2_k127_7156676_17 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000001202 121.0
HKD2_k127_7156676_18 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000697 128.0
HKD2_k127_7156676_19 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000002399 119.0
HKD2_k127_7156676_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.563e-313 969.0
HKD2_k127_7156676_20 sequence-specific DNA binding K07729 - - 0.000000000000000000503 89.0
HKD2_k127_7156676_21 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000002153 88.0
HKD2_k127_7156676_22 TIGRFAM DNA binding domain protein, excisionase family - - - 0.000000005918 61.0
HKD2_k127_7156676_23 TIGRFAM DNA binding domain protein, excisionase family - - - 0.000005323 51.0
HKD2_k127_7156676_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 8.401e-225 703.0
HKD2_k127_7156676_4 Cytochrome c - - - 1.302e-195 617.0
HKD2_k127_7156676_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 605.0
HKD2_k127_7156676_6 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 373.0
HKD2_k127_7156676_7 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007225 281.0
HKD2_k127_7156676_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001591 291.0
HKD2_k127_7156676_9 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001094 282.0
HKD2_k127_7228180_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 508.0
HKD2_k127_7228180_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 449.0
HKD2_k127_7228180_12 Thioredoxin-like - - - 0.0005238 51.0
HKD2_k127_7228180_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 436.0
HKD2_k127_7228180_3 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 361.0
HKD2_k127_7228180_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 320.0
HKD2_k127_7228180_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001008 227.0
HKD2_k127_7228180_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000005752 162.0
HKD2_k127_7228180_7 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000002887 146.0
HKD2_k127_7228180_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000008178 119.0
HKD2_k127_7228180_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000009095 106.0
HKD2_k127_7229594_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1285.0
HKD2_k127_7229594_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 9.022e-254 801.0
HKD2_k127_7229594_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000002375 247.0
HKD2_k127_7229594_11 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000007002 230.0
HKD2_k127_7229594_12 Cytochrome c - - - 0.00000000000000000000000000000000000008888 149.0
HKD2_k127_7229594_13 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000001642 119.0
HKD2_k127_7229594_14 Universal stress protein - - - 0.00000001343 68.0
HKD2_k127_7229594_15 receptor K02014 - - 0.0000007823 60.0
HKD2_k127_7229594_2 PFAM Leukotriene A4 hydrolase, C-terminal - - - 7.698e-211 677.0
HKD2_k127_7229594_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 462.0
HKD2_k127_7229594_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 472.0
HKD2_k127_7229594_5 Phospholipase D. Active site motifs. K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 339.0
HKD2_k127_7229594_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 335.0
HKD2_k127_7229594_7 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 301.0
HKD2_k127_7229594_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 309.0
HKD2_k127_7229594_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 261.0
HKD2_k127_7244365_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 487.0
HKD2_k127_7244365_1 threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 344.0
HKD2_k127_7244365_3 conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000004663 247.0
HKD2_k127_7244365_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000007285 204.0
HKD2_k127_7244365_5 Copper binding periplasmic protein CusF K07152 - - 0.0000000000000000000000000002351 134.0
HKD2_k127_7244365_6 Cytochrome c - - - 0.00000000006549 74.0
HKD2_k127_7251586_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 393.0
HKD2_k127_7251586_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001648 273.0
HKD2_k127_7251586_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000004825 258.0
HKD2_k127_7251586_3 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000000006739 232.0
HKD2_k127_7251586_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000004832 188.0
HKD2_k127_7258413_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
HKD2_k127_7258413_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000003709 111.0
HKD2_k127_7258413_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000009336 106.0
HKD2_k127_7258413_3 mRNA binding - - - 0.000000000000005225 76.0
HKD2_k127_7277464_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 391.0
HKD2_k127_7277464_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593,K13745 - 4.1.1.105,4.1.1.28,4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 388.0
HKD2_k127_7277464_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000002251 146.0
HKD2_k127_7277464_11 RNA recognition motif - - - 0.00000000000000000000000000002542 119.0
HKD2_k127_7277464_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000001075 100.0
HKD2_k127_7277464_13 Metallo-beta-lactamase superfamily - - - 0.00000000000000000949 94.0
HKD2_k127_7277464_14 DinB superfamily - - - 0.00000000000000003058 89.0
HKD2_k127_7277464_15 Cupin domain - - - 0.00000000000000004277 86.0
HKD2_k127_7277464_16 Tellurite resistance protein TerB - - - 0.000838 46.0
HKD2_k127_7277464_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003941 251.0
HKD2_k127_7277464_3 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
HKD2_k127_7277464_4 Amino-transferase class IV K00824,K00826 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000000000000000008922 221.0
HKD2_k127_7277464_5 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000001298 203.0
HKD2_k127_7277464_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000187 191.0
HKD2_k127_7277464_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
HKD2_k127_7277464_8 Histidine kinase K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000003564 189.0
HKD2_k127_7277464_9 peptidase C26 K07010 - - 0.000000000000000000000000000000000000001214 156.0
HKD2_k127_729194_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 351.0
HKD2_k127_729194_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000003546 79.0
HKD2_k127_7312140_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 335.0
HKD2_k127_73852_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 329.0
HKD2_k127_73852_1 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000001213 211.0
HKD2_k127_73852_10 Acetyltransferase (GNAT) domain - - - 0.0000000005719 73.0
HKD2_k127_73852_2 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000259 182.0
HKD2_k127_73852_3 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000005131 183.0
HKD2_k127_73852_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000007758 162.0
HKD2_k127_73852_5 methyltransferase activity K15256 - - 0.00000000000000000000000003168 126.0
HKD2_k127_73852_6 Glycosyl transferase, family 2 - - - 0.000000000000000002931 100.0
HKD2_k127_73852_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000004151 85.0
HKD2_k127_73852_8 transferase activity, transferring glycosyl groups - - - 0.0000000000015 81.0
HKD2_k127_73852_9 Iron-sulfur cluster-binding domain - - - 0.000000000003369 68.0
HKD2_k127_7477986_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.895e-309 985.0
HKD2_k127_7477986_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 583.0
HKD2_k127_7477986_11 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000005451 132.0
HKD2_k127_7477986_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 581.0
HKD2_k127_7477986_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 532.0
HKD2_k127_7477986_4 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 378.0
HKD2_k127_7477986_5 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 312.0
HKD2_k127_7477986_6 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000001469 238.0
HKD2_k127_7477986_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000003352 226.0
HKD2_k127_7477986_8 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000001526 193.0
HKD2_k127_7477986_9 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000859 153.0
HKD2_k127_7655242_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 480.0
HKD2_k127_7655242_1 phosphoserine phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 401.0
HKD2_k127_7655242_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000001566 206.0
HKD2_k127_7655242_3 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000007883 201.0
HKD2_k127_7667575_0 Hydrolase CocE NonD family - - - 3.114e-306 956.0
HKD2_k127_7667575_1 enterobactin catabolic process - - - 2.009e-252 798.0
HKD2_k127_7667575_2 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 511.0
HKD2_k127_7667575_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 308.0
HKD2_k127_7667575_4 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000001166 179.0
HKD2_k127_7667575_5 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000000003959 129.0
HKD2_k127_7667575_6 Bacterial antitoxin of type II TA system, VapB - - - 0.0002396 54.0
HKD2_k127_7676829_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008159 366.0
HKD2_k127_7676829_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
HKD2_k127_7676829_10 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.000000000000000000000004217 115.0
HKD2_k127_7676829_11 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000001044 89.0
HKD2_k127_7676829_12 Helix-hairpin-helix motif K02237 - - 0.0000000000000003854 85.0
HKD2_k127_7676829_13 META domain - - - 0.0000001172 63.0
HKD2_k127_7676829_14 Type II transport protein GspH K08084 - - 0.00001464 57.0
HKD2_k127_7676829_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000003101 282.0
HKD2_k127_7676829_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HKD2_k127_7676829_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001286 229.0
HKD2_k127_7676829_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000103 161.0
HKD2_k127_7676829_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000227 154.0
HKD2_k127_7676829_7 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000001836 137.0
HKD2_k127_7676829_8 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000006808 130.0
HKD2_k127_7676829_9 Yqey-like protein K09117 - - 0.0000000000000000000000000000001887 128.0
HKD2_k127_7687292_0 Involved in the tonB-independent uptake of proteins - - - 2.992e-232 747.0
HKD2_k127_7687292_1 Involved in the tonB-independent uptake of proteins - - - 2.014e-229 737.0
HKD2_k127_7687292_10 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000001806 198.0
HKD2_k127_7687292_11 CGNR zinc finger - - - 0.000000000000000000000000005167 121.0
HKD2_k127_7687292_12 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000002723 111.0
HKD2_k127_7687292_13 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000004096 117.0
HKD2_k127_7687292_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000001174 100.0
HKD2_k127_7687292_2 Involved in the tonB-independent uptake of proteins - - - 1.83e-228 751.0
HKD2_k127_7687292_3 Involved in the tonB-independent uptake of proteins - - - 6.628e-206 677.0
HKD2_k127_7687292_4 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 527.0
HKD2_k127_7687292_5 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 437.0
HKD2_k127_7687292_6 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 313.0
HKD2_k127_7687292_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 322.0
HKD2_k127_7687292_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
HKD2_k127_7687292_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000003594 237.0
HKD2_k127_769798_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 349.0
HKD2_k127_769798_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 307.0
HKD2_k127_769798_2 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000003409 131.0
HKD2_k127_769798_3 von Willebrand factor, type A - - - 0.00000000000000000000000006246 127.0
HKD2_k127_769798_4 Tetratricopeptide repeat K08309 - - 0.0000000007908 74.0
HKD2_k127_7698825_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 370.0
HKD2_k127_7698825_1 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000004834 160.0
HKD2_k127_7699048_0 imidazolonepropionase activity K01443 - 3.5.1.25 1.943e-207 676.0
HKD2_k127_7699048_1 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000001751 218.0
HKD2_k127_7699048_2 Protein of unknown function (DUF2911) - - - 0.00000000000000003923 93.0
HKD2_k127_7699048_3 aminopeptidase activity K07004 - - 0.0003019 55.0
HKD2_k127_7705515_0 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000003749 202.0
HKD2_k127_7705515_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000001554 115.0
HKD2_k127_7705515_3 peptidase S1 and S6, chymotrypsin Hap K01337 - 3.4.21.50 0.00000000000000000002388 106.0
HKD2_k127_7727030_0 Endoribonuclease L-PSP - - - 7.108e-214 676.0
HKD2_k127_7727030_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 588.0
HKD2_k127_7727030_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 444.0
HKD2_k127_7727030_3 peptidase K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 388.0
HKD2_k127_7727030_4 - - - - 0.00000000000000000000001133 105.0
HKD2_k127_7738380_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.252e-287 901.0
HKD2_k127_7738380_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.157e-282 877.0
HKD2_k127_7738380_10 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000008354 116.0
HKD2_k127_7738380_11 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000007536 87.0
HKD2_k127_7738380_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000002409 61.0
HKD2_k127_7738380_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 510.0
HKD2_k127_7738380_3 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 495.0
HKD2_k127_7738380_4 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 448.0
HKD2_k127_7738380_5 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 364.0
HKD2_k127_7738380_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 327.0
HKD2_k127_7738380_7 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
HKD2_k127_7738380_8 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000005226 161.0
HKD2_k127_7738380_9 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000001046 139.0
HKD2_k127_7740521_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 518.0
HKD2_k127_7740521_1 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 435.0
HKD2_k127_7740521_2 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 399.0
HKD2_k127_7740521_3 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 360.0
HKD2_k127_7740521_4 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000007772 117.0
HKD2_k127_7746680_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.928e-287 919.0
HKD2_k127_7746680_1 Belongs to the ClpA ClpB family K03696 - - 4.526e-285 897.0
HKD2_k127_7746680_10 Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006875 309.0
HKD2_k127_7746680_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000006823 274.0
HKD2_k127_7746680_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD2_k127_7746680_13 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001449 266.0
HKD2_k127_7746680_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004659 265.0
HKD2_k127_7746680_15 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008329 252.0
HKD2_k127_7746680_16 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000001264 242.0
HKD2_k127_7746680_17 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004557 251.0
HKD2_k127_7746680_18 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000009806 246.0
HKD2_k127_7746680_19 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000713 242.0
HKD2_k127_7746680_2 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 418.0
HKD2_k127_7746680_20 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000002615 207.0
HKD2_k127_7746680_21 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000005877 207.0
HKD2_k127_7746680_22 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000002331 204.0
HKD2_k127_7746680_23 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000005541 187.0
HKD2_k127_7746680_24 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000006897 165.0
HKD2_k127_7746680_25 OmpA family K03640 - - 0.000000000000000000000000000000000000002499 154.0
HKD2_k127_7746680_26 - K07018 - - 0.0000000000000000000000000000000000000324 166.0
HKD2_k127_7746680_27 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000001153 131.0
HKD2_k127_7746680_28 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000542 143.0
HKD2_k127_7746680_29 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000000000000006229 126.0
HKD2_k127_7746680_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 379.0
HKD2_k127_7746680_30 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000007067 132.0
HKD2_k127_7746680_31 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000002911 133.0
HKD2_k127_7746680_32 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000007615 117.0
HKD2_k127_7746680_33 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.00000000000000000000000000158 114.0
HKD2_k127_7746680_34 Outer membrane lipoprotein - - - 0.000000000000000000000006052 116.0
HKD2_k127_7746680_35 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000009213 111.0
HKD2_k127_7746680_36 Lipopolysaccharide-assembly - - - 0.0000000000000001344 95.0
HKD2_k127_7746680_37 PFAM Outer membrane K06142 - - 0.000000000000003241 85.0
HKD2_k127_7746680_38 thiolester hydrolase activity K17362 - - 0.000000000000005477 88.0
HKD2_k127_7746680_39 Ribosomal protein S20 K02968 - - 0.000000000666 63.0
HKD2_k127_7746680_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 342.0
HKD2_k127_7746680_40 TIGRFAM TonB family K03832 - - 0.000000514 60.0
HKD2_k127_7746680_41 PFAM Transglutaminase-like - - - 0.000001378 60.0
HKD2_k127_7746680_5 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 336.0
HKD2_k127_7746680_6 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 315.0
HKD2_k127_7746680_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 321.0
HKD2_k127_7746680_8 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 320.0
HKD2_k127_7746680_9 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003774 307.0
HKD2_k127_7753226_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0016829,GO:0016830,GO:0016833 4.1.3.1 0.0 1165.0
HKD2_k127_7753226_1 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 1.422e-206 658.0
HKD2_k127_7753226_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000004438 215.0
HKD2_k127_7775335_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 315.0
HKD2_k127_7775335_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001777 295.0
HKD2_k127_7775335_2 selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005092 272.0
HKD2_k127_7775335_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004731 268.0
HKD2_k127_7775335_4 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001552 245.0
HKD2_k127_7775335_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000001337 176.0
HKD2_k127_7775335_6 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000000001393 148.0
HKD2_k127_7775335_7 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000002449 142.0
HKD2_k127_7788085_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 475.0
HKD2_k127_7788085_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000002433 201.0
HKD2_k127_7794416_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 543.0
HKD2_k127_7794416_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 349.0
HKD2_k127_7794416_2 wide pore channel activity K07267 - - 0.000000000000000000000000000000000000000000000000398 194.0
HKD2_k127_7824302_0 Methionine synthase K00548 - 2.1.1.13 0.0 1325.0
HKD2_k127_7824302_1 Protein conserved in bacteria K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 477.0
HKD2_k127_7824302_10 peptidyl-tyrosine sulfation - - - 0.00000001622 66.0
HKD2_k127_7824302_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 410.0
HKD2_k127_7824302_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 396.0
HKD2_k127_7824302_4 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 292.0
HKD2_k127_7824302_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 264.0
HKD2_k127_7824302_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007487 260.0
HKD2_k127_7824302_7 gluconolactonase activity K01053,K04565 - 1.15.1.1,3.1.1.17 0.00000000000000000000000000000000000000000000000000005858 203.0
HKD2_k127_7824302_8 SMART Transcription regulator, AsnC-type K03718,K03719 - - 0.00000000000000000000000000000000000000000000001173 176.0
HKD2_k127_7824302_9 DinB family - - - 0.000000000000000000000000000000000000008578 162.0
HKD2_k127_7894283_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 445.0
HKD2_k127_7894283_1 - - - - 0.0000000000000000001435 103.0
HKD2_k127_7899023_0 OmpA family K03640 - - 0.000000000000000000000000000000000004519 143.0
HKD2_k127_7899023_1 AhpC/TSA family - - - 0.00000000000000000000000000000000006459 147.0
HKD2_k127_7899023_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000004815 123.0
HKD2_k127_7899023_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000006442 116.0
HKD2_k127_7899023_4 Regulatory protein MarR - - - 0.000000000000000000000000638 114.0
HKD2_k127_7899023_5 Alpha/beta hydrolase family - - - 0.00000000000000000004427 91.0
HKD2_k127_7899023_6 Transcription factor zinc-finger K09981 - - 0.0008628 49.0
HKD2_k127_7920644_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
HKD2_k127_7920644_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 365.0
HKD2_k127_7920644_10 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.00000000000000000000000007091 116.0
HKD2_k127_7920644_11 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000000000000001187 112.0
HKD2_k127_7920644_12 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000867 118.0
HKD2_k127_7920644_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000001673 95.0
HKD2_k127_7920644_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 359.0
HKD2_k127_7920644_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 318.0
HKD2_k127_7920644_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
HKD2_k127_7920644_5 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006185 282.0
HKD2_k127_7920644_6 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000003466 205.0
HKD2_k127_7920644_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000003635 205.0
HKD2_k127_7920644_8 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000004098 187.0
HKD2_k127_7920644_9 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000002039 157.0
HKD2_k127_7922175_0 Methionine synthase K00548 - 2.1.1.13 0.0 1314.0
HKD2_k127_7922175_1 Protein conserved in bacteria K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 471.0
HKD2_k127_7922175_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 284.0
HKD2_k127_7927317_0 Cytochrome c - - - 5.197e-200 631.0
HKD2_k127_7927317_1 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000005356 189.0
HKD2_k127_7927317_2 Protein of unknown function (DUF2945) - - - 0.00000000000000000000000000000000124 136.0
HKD2_k127_7947798_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 548.0
HKD2_k127_7947798_1 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 319.0
HKD2_k127_7947798_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001157 290.0
HKD2_k127_7947798_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000001072 161.0
HKD2_k127_7947798_4 - K01992,K19341 - - 0.00000000000000000000000000000003495 141.0
HKD2_k127_7947798_5 Biogenesis protein - - - 0.0000000000000000000000004443 120.0
HKD2_k127_7947798_6 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0000000000000002933 89.0
HKD2_k127_7947798_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.0000000002498 74.0
HKD2_k127_7947798_8 - - - - 0.0003269 53.0
HKD2_k127_7962841_0 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000006989 212.0
HKD2_k127_7962841_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441,K03522 - 1.12.98.1,1.2.7.1 0.000000000000000000000001973 109.0
HKD2_k127_7962841_2 deoxyhypusine monooxygenase activity - - - 0.00000001726 68.0
HKD2_k127_7967792_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1473.0
HKD2_k127_7967792_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 398.0
HKD2_k127_7967792_10 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001443 63.0
HKD2_k127_7967792_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 329.0
HKD2_k127_7967792_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003312 259.0
HKD2_k127_7967792_4 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000203 230.0
HKD2_k127_7967792_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000001513 217.0
HKD2_k127_7967792_6 translation initiation factor activity K20276 - - 0.0000000000000000000000000000000000000000000000000001212 209.0
HKD2_k127_7967792_7 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000749 168.0
HKD2_k127_7967792_8 pre-mRNA 3' end processing protein K15542 GO:0000003,GO:0000375,GO:0000377,GO:0000398,GO:0001650,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005847,GO:0005849,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006351,GO:0006353,GO:0006366,GO:0006369,GO:0006378,GO:0006379,GO:0006396,GO:0006397,GO:0006403,GO:0006405,GO:0006406,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0006974,GO:0007276,GO:0007283,GO:0008104,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015931,GO:0016070,GO:0016071,GO:0016604,GO:0016607,GO:0018130,GO:0019438,GO:0019953,GO:0022414,GO:0031123,GO:0031124,GO:0031503,GO:0031974,GO:0031981,GO:0032501,GO:0032504,GO:0032774,GO:0032991,GO:0033036,GO:0033554,GO:0034613,GO:0034641,GO:0034645,GO:0034654,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043631,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0044703,GO:0045184,GO:0046483,GO:0046907,GO:0048232,GO:0048609,GO:0050657,GO:0050658,GO:0050896,GO:0051028,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0051704,GO:0051716,GO:0070013,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0090305,GO:0090501,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000002052 85.0
HKD2_k127_7967792_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000235 77.0
HKD2_k127_7971638_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
HKD2_k127_7971638_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 527.0
HKD2_k127_7971638_2 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 377.0
HKD2_k127_7971638_3 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 317.0
HKD2_k127_7971638_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001182 193.0
HKD2_k127_7971638_5 FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000137 200.0
HKD2_k127_7971638_6 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000000000004679 209.0
HKD2_k127_7971638_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000004529 128.0
HKD2_k127_7995719_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1140.0
HKD2_k127_7995719_1 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 5.808e-288 909.0
HKD2_k127_7995719_10 glyoxalase III activity - - - 0.00000000000000000000000000000000000000003132 162.0
HKD2_k127_7995719_11 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000004682 154.0
HKD2_k127_7995719_12 - - - - 0.0000000000000000000000000000000000000002776 156.0
HKD2_k127_7995719_13 DinB family - - - 0.00000000000000000000000000000000000001169 154.0
HKD2_k127_7995719_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000013 142.0
HKD2_k127_7995719_16 FecR protein - - - 0.000003048 59.0
HKD2_k127_7995719_17 - - - - 0.0003034 46.0
HKD2_k127_7995719_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 568.0
HKD2_k127_7995719_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 497.0
HKD2_k127_7995719_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 382.0
HKD2_k127_7995719_5 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003556 257.0
HKD2_k127_7995719_6 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000003002 256.0
HKD2_k127_7995719_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000116 230.0
HKD2_k127_7995719_8 protein-glutamate methylesterase activity K00575,K03412,K03413 - 2.1.1.80,3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000115 177.0
HKD2_k127_7995719_9 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000002051 163.0
HKD2_k127_8017262_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 410.0
HKD2_k127_8017262_1 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000002928 205.0
HKD2_k127_8017262_2 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000001182 167.0
HKD2_k127_8017262_3 PFAM CBS domain containing protein - - - 0.0000000000000000000002178 105.0
HKD2_k127_8026490_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 387.0
HKD2_k127_8029899_0 Protein kinase domain K12132 - 2.7.11.1 2.872e-231 745.0
HKD2_k127_8029899_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 351.0
HKD2_k127_8029899_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000008373 142.0
HKD2_k127_8062162_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1280.0
HKD2_k127_8062162_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 484.0
HKD2_k127_8062162_2 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000000000000003597 133.0
HKD2_k127_8062162_3 PFAM Peptidase M23 - - - 0.000000000000000004766 96.0
HKD2_k127_8062162_4 O-Antigen ligase - - - 0.0000003785 63.0
HKD2_k127_8118758_0 OPT oligopeptide transporter protein - - - 6.798e-306 970.0
HKD2_k127_8118758_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 467.0
HKD2_k127_8118758_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 389.0
HKD2_k127_8118758_3 - - - - 0.00000000000000000000000000000000007162 147.0
HKD2_k127_8118758_4 - - - - 0.000000000000000000000000000001187 129.0
HKD2_k127_8118758_5 DoxX K15977 - - 0.000000000001024 82.0
HKD2_k127_8118758_6 D-aminopeptidase K16203 - - 0.000000009225 57.0
HKD2_k127_8120348_0 cluster binding protein K18929 - - 6.908e-214 674.0
HKD2_k127_8120348_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 6.52e-204 650.0
HKD2_k127_8120348_10 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000000000000000007225 172.0
HKD2_k127_8120348_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000003215 63.0
HKD2_k127_8120348_12 Putative MetA-pathway of phenol degradation - - - 0.000000139 53.0
HKD2_k127_8120348_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 489.0
HKD2_k127_8120348_3 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 444.0
HKD2_k127_8120348_4 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 362.0
HKD2_k127_8120348_5 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 326.0
HKD2_k127_8120348_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
HKD2_k127_8120348_7 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000004634 241.0
HKD2_k127_8120348_8 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000001038 246.0
HKD2_k127_8120348_9 membrane - - - 0.0000000000000000000000000000000000000000000000000000000005349 208.0
HKD2_k127_8127502_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 626.0
HKD2_k127_8127502_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 327.0
HKD2_k127_8127502_2 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000012 125.0
HKD2_k127_8127502_3 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000001025 65.0
HKD2_k127_8127502_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K22345 GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.00000000001265 64.0
HKD2_k127_8133300_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.732e-215 679.0
HKD2_k127_8133300_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 547.0
HKD2_k127_8133300_2 lipopolysaccharide transport K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 467.0
HKD2_k127_8133300_3 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 308.0
HKD2_k127_8133300_4 PFAM ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 291.0
HKD2_k127_8133300_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000000000000001152 187.0
HKD2_k127_8134125_0 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 462.0
HKD2_k127_8161235_0 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 419.0
HKD2_k127_8161235_1 Protein conserved in bacteria - - - 0.0000000000000000000000000009028 124.0
HKD2_k127_8161235_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0001254 50.0
HKD2_k127_8183289_0 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000007656 119.0
HKD2_k127_8183289_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000004035 51.0
HKD2_k127_8228724_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 554.0
HKD2_k127_8228724_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 433.0
HKD2_k127_8228724_10 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000003432 141.0
HKD2_k127_8228724_11 Hfq protein - - - 0.00000000000000000000000000007052 127.0
HKD2_k127_8228724_12 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000005987 119.0
HKD2_k127_8228724_13 peptidase inhibitor activity - - - 0.00000000000000004881 94.0
HKD2_k127_8228724_14 cellulose binding - - - 0.00000000000000007033 94.0
HKD2_k127_8228724_15 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000005641 81.0
HKD2_k127_8228724_2 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 441.0
HKD2_k127_8228724_3 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 406.0
HKD2_k127_8228724_4 protein conserved in bacteria K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 402.0
HKD2_k127_8228724_5 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 357.0
HKD2_k127_8228724_6 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000002119 245.0
HKD2_k127_8228724_7 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000224 186.0
HKD2_k127_8228724_8 Large extracellular alpha-helical protein K20276 - - 0.00000000000000000000000000000000000000005448 164.0
HKD2_k127_8228724_9 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000145 152.0
HKD2_k127_8258161_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2843.0
HKD2_k127_8258161_1 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01539 - 3.6.3.9 0.0 1057.0
HKD2_k127_8258161_10 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 331.0
HKD2_k127_8258161_11 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 301.0
HKD2_k127_8258161_12 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001811 233.0
HKD2_k127_8258161_13 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000005053 224.0
HKD2_k127_8258161_14 - - - - 0.000000000000000000000000000000000000000000000000001771 203.0
HKD2_k127_8258161_15 cytochrome - - - 0.0000000000000000000000000000000000000009142 160.0
HKD2_k127_8258161_16 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000001577 160.0
HKD2_k127_8258161_17 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000007913 140.0
HKD2_k127_8258161_18 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000513 132.0
HKD2_k127_8258161_19 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000006293 131.0
HKD2_k127_8258161_2 ErfK YbiS YcfS YnhG family protein K21470 - - 8.072e-214 680.0
HKD2_k127_8258161_20 - - - - 0.000000000000000000000000000005089 139.0
HKD2_k127_8258161_21 - - - - 0.00000000000000000000000001254 127.0
HKD2_k127_8258161_22 MerR, DNA binding - - - 0.00000000000000000000000005546 126.0
HKD2_k127_8258161_23 PQQ enzyme repeat - - - 0.0000000000000000000001119 115.0
HKD2_k127_8258161_24 YXWGXW repeat (2 copies) - - - 0.0000000000000000005202 90.0
HKD2_k127_8258161_25 Type III secretion system lipoprotein chaperone (YscW) - - - 0.000000000000001512 82.0
HKD2_k127_8258161_26 PFAM PKD domain containing protein - - - 0.00000000000009241 85.0
HKD2_k127_8258161_28 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00003713 54.0
HKD2_k127_8258161_3 transmembrane transporter activity K03296 - - 5.563e-206 679.0
HKD2_k127_8258161_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 563.0
HKD2_k127_8258161_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 458.0
HKD2_k127_8258161_6 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 455.0
HKD2_k127_8258161_7 amino acid K03293,K16238,K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 426.0
HKD2_k127_8258161_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 362.0
HKD2_k127_8258161_9 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 337.0
HKD2_k127_8268097_0 Dehydrogenase E1 component K11381 - 1.2.4.4 1.754e-228 720.0
HKD2_k127_8365554_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 301.0
HKD2_k127_8365554_1 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002453 235.0
HKD2_k127_8416093_0 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 364.0
HKD2_k127_8416093_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000006848 244.0
HKD2_k127_8416093_2 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000008135 238.0
HKD2_k127_8416093_3 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000002686 222.0
HKD2_k127_8416093_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000007407 75.0
HKD2_k127_8422515_0 Beta-lactamase - - - 4.747e-283 891.0
HKD2_k127_8422515_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
HKD2_k127_8422515_2 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 390.0
HKD2_k127_8422515_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 278.0
HKD2_k127_8422515_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000000000000002974 213.0
HKD2_k127_8443508_0 L-Lactate permease K03303 - - 7.963e-272 844.0
HKD2_k127_8521396_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 569.0
HKD2_k127_8521396_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 466.0
HKD2_k127_8521396_10 Phage integrase family - - - 0.00000000000000000000002042 104.0
HKD2_k127_8521396_11 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000001714 107.0
HKD2_k127_8521396_12 Regulatory protein - - - 0.000000000000007458 81.0
HKD2_k127_8521396_13 Domain of unknown function (DUF309) K09763 - - 0.00000000000005109 78.0
HKD2_k127_8521396_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 374.0
HKD2_k127_8521396_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 342.0
HKD2_k127_8521396_4 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
HKD2_k127_8521396_5 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000001242 223.0
HKD2_k127_8521396_6 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000007351 185.0
HKD2_k127_8521396_7 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000009543 174.0
HKD2_k127_8521396_8 - - - - 0.000000000000000000000000000000006321 135.0
HKD2_k127_8521396_9 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000002609 111.0
HKD2_k127_8545837_0 4Fe-4S binding domain - - - 8.816e-233 742.0
HKD2_k127_8545837_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.199e-219 694.0
HKD2_k127_8545837_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 337.0
HKD2_k127_8545837_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
HKD2_k127_8545837_12 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005235 278.0
HKD2_k127_8545837_13 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 281.0
HKD2_k127_8545837_14 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001428 241.0
HKD2_k127_8545837_15 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000001897 198.0
HKD2_k127_8545837_16 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000002071 167.0
HKD2_k127_8545837_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000004293 148.0
HKD2_k127_8545837_18 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000006211 134.0
HKD2_k127_8545837_19 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000006873 135.0
HKD2_k127_8545837_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 539.0
HKD2_k127_8545837_20 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000004589 116.0
HKD2_k127_8545837_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000006193 82.0
HKD2_k127_8545837_3 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 480.0
HKD2_k127_8545837_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
HKD2_k127_8545837_5 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 421.0
HKD2_k127_8545837_6 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 415.0
HKD2_k127_8545837_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 357.0
HKD2_k127_8545837_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 382.0
HKD2_k127_8545837_9 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 351.0
HKD2_k127_8641109_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 477.0
HKD2_k127_8641109_1 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 400.0
HKD2_k127_8641109_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 402.0
HKD2_k127_8641109_3 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001812 308.0
HKD2_k127_8641109_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007552 260.0
HKD2_k127_8641109_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
HKD2_k127_8641109_6 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000001269 164.0
HKD2_k127_8641109_7 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000002436 167.0
HKD2_k127_8666126_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 518.0
HKD2_k127_8666126_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 486.0
HKD2_k127_8666126_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000175 192.0
HKD2_k127_8666126_3 NmrA-like family - - - 0.00000000000000000000000000000000000001577 162.0
HKD2_k127_8671525_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 445.0
HKD2_k127_8671525_1 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 391.0
HKD2_k127_8671525_2 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001516 264.0
HKD2_k127_8671525_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000001273 192.0
HKD2_k127_8671525_4 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000394 154.0
HKD2_k127_8671525_5 - - - - 0.00000000000000000000000001492 114.0
HKD2_k127_8671525_6 - - - - 0.00000000000001182 85.0
HKD2_k127_8742172_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 585.0
HKD2_k127_8742172_1 Oligopeptide transporter OPT - - - 0.00000000000000000000000000000000000000000000001778 172.0
HKD2_k127_8763862_0 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 372.0
HKD2_k127_8763862_1 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
HKD2_k127_8763862_2 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000001632 204.0
HKD2_k127_8763862_3 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000001016 196.0
HKD2_k127_8763862_4 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000004028 127.0
HKD2_k127_8943629_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 372.0
HKD2_k127_8943629_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
HKD2_k127_8943629_10 protein conserved in bacteria - - - 0.0003289 53.0
HKD2_k127_8943629_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 318.0
HKD2_k127_8943629_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 305.0
HKD2_k127_8943629_4 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000001383 251.0
HKD2_k127_8943629_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000009537 231.0
HKD2_k127_8943629_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000002208 168.0
HKD2_k127_8943629_7 NUDIX domain - - - 0.0000000000000000000000000000000000000008689 154.0
HKD2_k127_8943629_8 Tetratricopeptide repeat - - - 0.0000000000002261 85.0
HKD2_k127_8943629_9 PAP2 superfamily - - - 0.000001531 59.0
HKD2_k127_8945635_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 540.0
HKD2_k127_8945635_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 354.0
HKD2_k127_8945635_2 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005359 295.0
HKD2_k127_8945635_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001835 265.0
HKD2_k127_8945635_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000002436 175.0
HKD2_k127_8945635_5 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000009851 102.0
HKD2_k127_8945635_6 - - - - 0.000004529 52.0
HKD2_k127_8945635_8 - - - - 0.0002886 51.0
HKD2_k127_8945635_9 Copper binding proteins, plastocyanin/azurin family - - - 0.0007214 50.0
HKD2_k127_8958311_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1197.0
HKD2_k127_8958311_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 570.0
HKD2_k127_8958311_10 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000004704 273.0
HKD2_k127_8958311_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002978 247.0
HKD2_k127_8958311_12 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000657 235.0
HKD2_k127_8958311_13 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000002501 219.0
HKD2_k127_8958311_14 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000001544 209.0
HKD2_k127_8958311_15 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000004758 177.0
HKD2_k127_8958311_16 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000006036 181.0
HKD2_k127_8958311_17 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000003241 143.0
HKD2_k127_8958311_18 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000003615 139.0
HKD2_k127_8958311_19 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000001021 130.0
HKD2_k127_8958311_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 542.0
HKD2_k127_8958311_20 domain, Protein - - - 0.0000000000000000000003825 115.0
HKD2_k127_8958311_21 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000003869 110.0
HKD2_k127_8958311_22 exo-alpha-(2->6)-sialidase activity - - - 0.00000000008249 77.0
HKD2_k127_8958311_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 514.0
HKD2_k127_8958311_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 401.0
HKD2_k127_8958311_5 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 365.0
HKD2_k127_8958311_6 PFAM Formiminotransferase K00603 - 2.1.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 345.0
HKD2_k127_8958311_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 361.0
HKD2_k127_8958311_8 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 303.0
HKD2_k127_8958311_9 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007786 282.0
HKD2_k127_8966664_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 7.401e-287 904.0
HKD2_k127_8966664_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 402.0
HKD2_k127_8968610_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 602.0
HKD2_k127_8968610_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000004814 114.0
HKD2_k127_8968610_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000004608 98.0
HKD2_k127_8986256_0 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000004515 192.0
HKD2_k127_8986256_1 DNA methylase K07316 - 2.1.1.72 0.00000000000000000000000000000003369 130.0
HKD2_k127_8986256_2 Peptidase M48 - - - 0.000000000000000002048 86.0
HKD2_k127_8986256_3 Membrane - - - 0.0000000003991 68.0
HKD2_k127_8986256_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001378 53.0
HKD2_k127_8988871_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 329.0
HKD2_k127_8988871_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 287.0
HKD2_k127_8988871_2 Peptidase M56 - - - 0.00000000000001465 86.0
HKD2_k127_8990107_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HKD2_k127_8990107_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000002678 151.0
HKD2_k127_8990107_2 DinB family - - - 0.000007631 54.0
HKD2_k127_8994762_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.687e-243 775.0
HKD2_k127_8994762_1 Amidohydrolase family - - - 2.397e-225 739.0
HKD2_k127_8994762_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000007867 208.0
HKD2_k127_8994762_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000007807 183.0
HKD2_k127_8994762_12 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000003065 179.0
HKD2_k127_8994762_13 STAS domain K04749 - - 0.0000000000000000000000000000000005219 135.0
HKD2_k127_8994762_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002529 128.0
HKD2_k127_8994762_15 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000006018 115.0
HKD2_k127_8994762_16 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000585 106.0
HKD2_k127_8994762_17 Zincin-like metallopeptidase - - - 0.00000000000000000000002436 113.0
HKD2_k127_8994762_18 - - - - 0.0000000000000000000001906 109.0
HKD2_k127_8994762_19 Protein of unknown function (DUF2905) - - - 0.0000000000000000001012 90.0
HKD2_k127_8994762_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.046e-214 688.0
HKD2_k127_8994762_20 Protein of unknown function (DUF503) K09764 - - 0.000000000000006868 78.0
HKD2_k127_8994762_21 protein conserved in archaea - - - 0.000000002218 69.0
HKD2_k127_8994762_22 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000001633 57.0
HKD2_k127_8994762_23 Bacterial antitoxin of type II TA system, VapB - - - 0.00000001646 58.0
HKD2_k127_8994762_24 nuclease activity - - - 0.00000004458 67.0
HKD2_k127_8994762_25 CAAX protease self-immunity K07052 - - 0.00009875 53.0
HKD2_k127_8994762_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 574.0
HKD2_k127_8994762_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 429.0
HKD2_k127_8994762_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 382.0
HKD2_k127_8994762_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 346.0
HKD2_k127_8994762_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
HKD2_k127_8994762_8 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000138 260.0
HKD2_k127_8994762_9 LuxR family transcriptional regulator K03424 - - 0.000000000000000000000000000000000000000000000000000000000001656 219.0
HKD2_k127_9003683_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.104e-296 927.0
HKD2_k127_9003683_1 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 607.0
HKD2_k127_9003683_10 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000002647 219.0
HKD2_k127_9003683_11 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000004092 171.0
HKD2_k127_9003683_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000008763 153.0
HKD2_k127_9003683_13 Tetratricopeptide repeat - - - 0.00000000000000000000000001298 120.0
HKD2_k127_9003683_14 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000001849 127.0
HKD2_k127_9003683_15 TIGRFAM TonB K03832 - - 0.00000000000000000000000007491 116.0
HKD2_k127_9003683_16 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000008015 106.0
HKD2_k127_9003683_17 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000001479 98.0
HKD2_k127_9003683_18 Glutathione peroxidase - - - 0.0000000000000000004882 102.0
HKD2_k127_9003683_19 oxidoreductase activity - - - 0.0000000000000000009119 101.0
HKD2_k127_9003683_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 509.0
HKD2_k127_9003683_20 ATPase or kinase K06925 - - 0.000000000000000001553 101.0
HKD2_k127_9003683_21 Copper resistance protein D K07245 - - 0.00000000000000007296 86.0
HKD2_k127_9003683_22 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006358 73.0
HKD2_k127_9003683_23 multi-organism process K03195 - - 0.0000001625 64.0
HKD2_k127_9003683_26 Belongs to the ompA family K03286 - - 0.0002404 51.0
HKD2_k127_9003683_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 307.0
HKD2_k127_9003683_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 324.0
HKD2_k127_9003683_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 328.0
HKD2_k127_9003683_6 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 307.0
HKD2_k127_9003683_7 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001338 263.0
HKD2_k127_9003683_8 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000001576 259.0
HKD2_k127_9003683_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000005735 228.0
HKD2_k127_9007103_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1255.0
HKD2_k127_9007103_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 577.0
HKD2_k127_9007103_10 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000007826 152.0
HKD2_k127_9007103_11 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000005993 145.0
HKD2_k127_9007103_12 G-D-S-L family lipolytic protein - - - 0.00000000000000000000000000001561 138.0
HKD2_k127_9007103_13 Diguanylate cyclase - - - 0.000000000000000000000000007981 126.0
HKD2_k127_9007103_14 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000001586 108.0
HKD2_k127_9007103_15 - - - - 0.0000000000001298 84.0
HKD2_k127_9007103_16 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000002518 54.0
HKD2_k127_9007103_2 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 432.0
HKD2_k127_9007103_3 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 362.0
HKD2_k127_9007103_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002858 247.0
HKD2_k127_9007103_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HKD2_k127_9007103_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000006133 215.0
HKD2_k127_9007103_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000002942 205.0
HKD2_k127_9007103_8 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000004819 173.0
HKD2_k127_9007103_9 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000002782 181.0
HKD2_k127_9042896_0 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001261 244.0
HKD2_k127_9042896_1 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000002059 162.0
HKD2_k127_9042896_2 - - - - 0.0000000000000000000000000000000007387 140.0
HKD2_k127_9042896_3 - - - - 0.0000000000000000008653 89.0
HKD2_k127_9042896_4 - - - - 0.00000000000000002014 94.0
HKD2_k127_9042896_5 - - - - 0.0000000001783 70.0
HKD2_k127_9043198_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.697e-274 858.0
HKD2_k127_9043198_1 Transcriptional regulator with HTH domain and aminotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 383.0
HKD2_k127_9043198_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 352.0
HKD2_k127_9043198_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 319.0
HKD2_k127_9043198_4 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000215 256.0
HKD2_k127_9043198_5 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000006132 198.0
HKD2_k127_9043198_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000002063 93.0
HKD2_k127_9043198_7 response regulator - - - 0.00000000000004167 81.0
HKD2_k127_9043198_8 Serine/Threonine protein kinases, catalytic domain K08884,K12132 - 2.7.11.1 0.000000001176 72.0
HKD2_k127_9043198_9 Domain of Unknown Function (DUF1206) - - - 0.000006193 57.0
HKD2_k127_9059722_0 Sortilin, neurotensin receptor 3, - - - 0.0 1217.0
HKD2_k127_9059722_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000001284 198.0
HKD2_k127_9067522_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 618.0
HKD2_k127_9067522_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 612.0
HKD2_k127_9067522_2 belongs to the aldehyde dehydrogenase family K00137 GO:0003674,GO:0003824,GO:0004029,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019145,GO:0033737,GO:0034641,GO:0042402,GO:0042802,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 1.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 579.0
HKD2_k127_9067522_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 351.0
HKD2_k127_9067522_4 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 333.0
HKD2_k127_9067522_5 Aminotransferase class-III K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
HKD2_k127_9067522_6 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001704 274.0
HKD2_k127_9067522_7 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004003 267.0
HKD2_k127_9067522_8 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000002057 249.0
HKD2_k127_9106003_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 3.708e-232 747.0
HKD2_k127_9106003_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 600.0
HKD2_k127_9106003_2 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000112 157.0
HKD2_k127_9106003_3 PIN domain - - - 0.000000000000000000000000007163 117.0
HKD2_k127_9106003_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000165 103.0
HKD2_k127_9106003_5 SpoVT / AbrB like domain - - - 0.00000000000001833 75.0
HKD2_k127_9110387_0 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 594.0
HKD2_k127_9110387_1 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 463.0
HKD2_k127_9110387_2 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 295.0
HKD2_k127_9110387_3 benzoyl-CoA reductase K04112 - 1.3.7.8 0.000000000000000000000000000000000006675 139.0
HKD2_k127_9110387_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.00000000000000000000000000000003255 136.0
HKD2_k127_9110387_5 methylamine metabolic process - - - 0.000000000000000000000000000003836 128.0
HKD2_k127_9110387_6 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000001427 121.0
HKD2_k127_9110387_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000002088 124.0
HKD2_k127_9133708_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.247e-274 870.0
HKD2_k127_9133708_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 386.0
HKD2_k127_9133708_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 390.0
HKD2_k127_9133708_3 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 301.0
HKD2_k127_9133708_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000001103 227.0
HKD2_k127_9133708_5 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000006211 150.0
HKD2_k127_9133708_6 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000004954 117.0
HKD2_k127_9133708_7 - - - - 0.000000000000549 76.0
HKD2_k127_9138177_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.747e-199 636.0
HKD2_k127_9138177_1 desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 312.0
HKD2_k127_9138177_10 von Willebrand factor, type A K07114 - - 0.000000007501 67.0
HKD2_k127_9138177_2 Alanine racemase K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 306.0
HKD2_k127_9138177_3 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
HKD2_k127_9138177_4 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
HKD2_k127_9138177_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000003461 180.0
HKD2_k127_9138177_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000004152 182.0
HKD2_k127_9138177_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000006826 136.0
HKD2_k127_9138177_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000545 139.0
HKD2_k127_9138177_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000005673 114.0
HKD2_k127_9138337_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 552.0
HKD2_k127_9138337_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 548.0
HKD2_k127_9138337_10 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
HKD2_k127_9138337_11 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000000007363 206.0
HKD2_k127_9138337_12 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000000003273 192.0
HKD2_k127_9138337_13 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000925 188.0
HKD2_k127_9138337_14 NUDIX domain - - - 0.00000000000000000000000000000000002445 141.0
HKD2_k127_9138337_15 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000001096 127.0
HKD2_k127_9138337_16 Transport permease protein - - - 0.0000000000000000000000000000002731 143.0
HKD2_k127_9138337_17 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000001221 130.0
HKD2_k127_9138337_18 - - - - 0.00000000006944 66.0
HKD2_k127_9138337_19 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000003843 68.0
HKD2_k127_9138337_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 485.0
HKD2_k127_9138337_20 Putative addiction module component - - - 0.0000000118 59.0
HKD2_k127_9138337_21 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000001608 62.0
HKD2_k127_9138337_22 - - - - 0.000001232 54.0
HKD2_k127_9138337_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 439.0
HKD2_k127_9138337_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 404.0
HKD2_k127_9138337_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 346.0
HKD2_k127_9138337_6 oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 311.0
HKD2_k127_9138337_7 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 315.0
HKD2_k127_9138337_8 SMART ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 304.0
HKD2_k127_9138337_9 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005909 301.0
HKD2_k127_9164694_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 422.0
HKD2_k127_9164694_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000005273 148.0
HKD2_k127_9164694_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000007929 139.0
HKD2_k127_9164694_3 - - - - 0.0000000006789 68.0
HKD2_k127_9166128_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.028e-287 895.0
HKD2_k127_9166128_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 5.089e-231 728.0
HKD2_k127_9166128_10 - - - - 0.0000000000000000000000000000000003627 138.0
HKD2_k127_9166128_11 cellulase activity - - - 0.0000000000000001704 90.0
HKD2_k127_9166128_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 536.0
HKD2_k127_9166128_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 368.0
HKD2_k127_9166128_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 322.0
HKD2_k127_9166128_5 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000008904 254.0
HKD2_k127_9166128_6 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000005563 209.0
HKD2_k127_9166128_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000002126 180.0
HKD2_k127_9166128_8 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000002182 188.0
HKD2_k127_9166128_9 of the beta-lactamase K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000001011 183.0
HKD2_k127_9186672_0 Involved in the tonB-independent uptake of proteins - - - 2.099e-226 729.0
HKD2_k127_9186672_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 383.0
HKD2_k127_9192541_0 Response regulator receiver - - - 5.143e-194 621.0
HKD2_k127_9192541_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 637.0
HKD2_k127_9192541_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 615.0
HKD2_k127_9192541_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 514.0
HKD2_k127_9192541_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 356.0
HKD2_k127_9192541_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 336.0
HKD2_k127_9192541_6 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001495 202.0
HKD2_k127_9192541_7 ACT domain - - - 0.000000000000000000000000000002783 132.0
HKD2_k127_9193372_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.198e-224 708.0
HKD2_k127_9193372_1 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 390.0
HKD2_k127_9193372_2 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 350.0
HKD2_k127_9193372_3 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000000003593 148.0
HKD2_k127_9193372_4 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000004418 112.0
HKD2_k127_9193372_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000009107 113.0
HKD2_k127_9193372_6 PFAM Carbamoyl-phosphate synthase L chain ATP-binding protein, Carbamoyl-phosphate synthetase large chain domain protein, biotin carboxylase domain protein K01961 - 6.3.4.14,6.4.1.2 0.00000003551 66.0
HKD2_k127_9193372_7 domain, Protein - - - 0.00000006564 66.0
HKD2_k127_9193372_8 TPR repeat - - - 0.0000001947 64.0
HKD2_k127_9204815_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000006529 252.0
HKD2_k127_9204815_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000957 179.0
HKD2_k127_9204815_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000004639 154.0
HKD2_k127_9204815_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000003782 88.0
HKD2_k127_9204815_4 response to oxidative stress - - - 0.0000000001087 71.0
HKD2_k127_9204815_5 - - - - 0.00000003828 60.0
HKD2_k127_9204815_6 PFAM ferredoxin K08954 - - 0.00001155 52.0
HKD2_k127_9204815_7 Sugar (and other) transporter - - - 0.0006466 48.0
HKD2_k127_9215032_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 542.0
HKD2_k127_9215032_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 549.0
HKD2_k127_9215032_10 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000004488 188.0
HKD2_k127_9215032_11 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000001614 188.0
HKD2_k127_9215032_12 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000002812 169.0
HKD2_k127_9215032_13 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000001345 181.0
HKD2_k127_9215032_14 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000007361 169.0
HKD2_k127_9215032_15 Evidence 4 Homologs of previously reported genes of - - - 0.000000000002576 74.0
HKD2_k127_9215032_16 Autotransporter beta-domain - - - 0.000000000005376 81.0
HKD2_k127_9215032_17 guanyl-nucleotide exchange factor activity K05349 - 3.2.1.21 0.000001219 62.0
HKD2_k127_9215032_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 480.0
HKD2_k127_9215032_3 cellulase activity K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 471.0
HKD2_k127_9215032_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 441.0
HKD2_k127_9215032_5 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 426.0
HKD2_k127_9215032_6 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003482 307.0
HKD2_k127_9215032_7 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000004833 194.0
HKD2_k127_9215032_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000001484 195.0
HKD2_k127_9215032_9 Metallo-peptidase family M12 - - - 0.000000000000000000000000000000000000000000001714 189.0
HKD2_k127_9227703_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 419.0
HKD2_k127_9227703_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
HKD2_k127_9230112_0 Large extracellular alpha-helical protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 377.0
HKD2_k127_9230112_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 333.0
HKD2_k127_9230112_2 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 354.0
HKD2_k127_9230112_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
HKD2_k127_9230112_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000002518 151.0
HKD2_k127_9230112_5 Belongs to the UPF0312 family - - - 0.0000000000000000000001359 115.0
HKD2_k127_9304956_0 PFAM Amidase - - - 4.55e-271 846.0
HKD2_k127_9304956_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 561.0
HKD2_k127_9304956_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 356.0
HKD2_k127_9304956_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 291.0
HKD2_k127_9304956_4 DinB family - - - 0.000000000000000000000000000000000001285 145.0
HKD2_k127_9304956_5 FOG TPR repeat SEL1 subfamily K07126 - - 0.00000000000000000001158 107.0
HKD2_k127_9304956_6 AsmA family K07289,K07290 - - 0.000000001572 71.0
HKD2_k127_9336855_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 544.0
HKD2_k127_9336855_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 533.0
HKD2_k127_9336855_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000005617 213.0
HKD2_k127_9336855_11 abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000002071 176.0
HKD2_k127_9336855_12 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000004765 147.0
HKD2_k127_9336855_13 AI-2E family transporter - - - 0.00000000000000000000000000000000008703 148.0
HKD2_k127_9336855_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000001471 132.0
HKD2_k127_9336855_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000002783 132.0
HKD2_k127_9336855_16 phosphorelay signal transduction system - - - 0.0000000000000000000000000002424 126.0
HKD2_k127_9336855_17 chlorophyll binding - - - 0.000000000000000000837 100.0
HKD2_k127_9336855_18 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.000000000000000002441 99.0
HKD2_k127_9336855_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 474.0
HKD2_k127_9336855_3 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 368.0
HKD2_k127_9336855_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 360.0
HKD2_k127_9336855_5 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 302.0
HKD2_k127_9336855_6 dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004171 285.0
HKD2_k127_9336855_7 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000009135 268.0
HKD2_k127_9336855_8 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 264.0
HKD2_k127_9336855_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000005444 219.0
HKD2_k127_9419452_0 ERAP1-like C-terminal domain K01263 - 3.4.11.14 4.828e-244 782.0
HKD2_k127_9419452_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 616.0
HKD2_k127_9419452_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000001609 139.0
HKD2_k127_9419452_3 Protein of unknown function (DUF962) - - - 0.00000000000000000005877 89.0
HKD2_k127_9454161_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 432.0
HKD2_k127_9454161_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 417.0
HKD2_k127_9454161_10 cyclic nucleotide-binding - - - 0.0000000000001727 83.0
HKD2_k127_9454161_11 - - - - 0.0004335 47.0
HKD2_k127_9454161_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 302.0
HKD2_k127_9454161_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 302.0
HKD2_k127_9454161_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003606 262.0
HKD2_k127_9454161_5 - - - - 0.000000000000000000000000000000000000000002562 173.0
HKD2_k127_9454161_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000002263 157.0
HKD2_k127_9454161_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000001989 161.0
HKD2_k127_9454161_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000003705 102.0
HKD2_k127_9454161_9 membrane K07058 - - 0.00000000000001543 86.0
HKD2_k127_9472911_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 608.0
HKD2_k127_9472911_1 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 602.0
HKD2_k127_9472911_10 TspO/MBR family K05770 - - 0.000000000000000000000000000271 126.0
HKD2_k127_9472911_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 533.0
HKD2_k127_9472911_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 474.0
HKD2_k127_9472911_4 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 452.0
HKD2_k127_9472911_5 DNA photolyase domain protein K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 331.0
HKD2_k127_9472911_6 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001368 258.0
HKD2_k127_9472911_7 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000003511 246.0
HKD2_k127_9472911_8 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000001054 196.0
HKD2_k127_9472911_9 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000005771 149.0
HKD2_k127_9507238_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003853 279.0
HKD2_k127_9507238_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
HKD2_k127_9507238_2 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001128 205.0
HKD2_k127_9507238_3 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000007481 148.0
HKD2_k127_9507238_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000006272 92.0
HKD2_k127_9507238_5 Putative zinc-finger - - - 0.000000001615 66.0
HKD2_k127_9512539_0 carboxypeptidase activity K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000002386 185.0
HKD2_k127_9512539_1 cyclic nucleotide-binding K10914 - - 0.00000000000000001175 96.0
HKD2_k127_9573291_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 527.0
HKD2_k127_9573291_1 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001011 259.0
HKD2_k127_9682428_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.29e-219 743.0
HKD2_k127_9682428_1 Involved in the tonB-independent uptake of proteins - - - 4.26e-201 661.0
HKD2_k127_9682428_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 406.0
HKD2_k127_9682428_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
HKD2_k127_9682428_4 HEPN domain - - - 0.0000000000000000000000001954 114.0
HKD2_k127_9682428_5 Peptidase family M28 - - - 0.00001587 56.0
HKD2_k127_9683371_0 AAA ATPase domain - - - 0.0 1085.0
HKD2_k127_9683371_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000001796 121.0
HKD2_k127_9691914_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 412.0
HKD2_k127_9691914_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000001137 271.0
HKD2_k127_9691914_2 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000006337 192.0
HKD2_k127_9691914_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000001067 128.0
HKD2_k127_9762749_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1051.0
HKD2_k127_9762749_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.157e-237 786.0
HKD2_k127_9762749_10 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 392.0
HKD2_k127_9762749_11 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 358.0
HKD2_k127_9762749_12 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 351.0
HKD2_k127_9762749_13 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000414 251.0
HKD2_k127_9762749_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000006698 239.0
HKD2_k127_9762749_15 dihydrofolate reductase activity K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000001494 236.0
HKD2_k127_9762749_16 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000001244 235.0
HKD2_k127_9762749_17 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000001432 231.0
HKD2_k127_9762749_18 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000003953 230.0
HKD2_k127_9762749_19 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000002653 213.0
HKD2_k127_9762749_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 5.241e-226 728.0
HKD2_k127_9762749_20 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000001599 198.0
HKD2_k127_9762749_21 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000002098 194.0
HKD2_k127_9762749_22 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000003781 178.0
HKD2_k127_9762749_23 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000002106 194.0
HKD2_k127_9762749_24 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000007883 179.0
HKD2_k127_9762749_25 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000005886 176.0
HKD2_k127_9762749_26 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000008159 158.0
HKD2_k127_9762749_27 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000006658 171.0
HKD2_k127_9762749_28 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000002574 154.0
HKD2_k127_9762749_29 - - - - 0.000000000000000000000000000000000000979 151.0
HKD2_k127_9762749_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 2.976e-210 663.0
HKD2_k127_9762749_30 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000001638 142.0
HKD2_k127_9762749_31 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000005775 149.0
HKD2_k127_9762749_32 MgtC family K07507 - - 0.000000000000000000000000000000001651 149.0
HKD2_k127_9762749_33 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002446 141.0
HKD2_k127_9762749_34 - - - - 0.000000000000000000000001109 120.0
HKD2_k127_9762749_35 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000432 109.0
HKD2_k127_9762749_36 - - - - 0.00000000000000000000274 106.0
HKD2_k127_9762749_37 carboxylic ester hydrolase activity - - - 0.0000000000000000004371 96.0
HKD2_k127_9762749_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.65e-199 632.0
HKD2_k127_9762749_40 Sigma-70, region 4 K03088 - - 0.0000000129 64.0
HKD2_k127_9762749_41 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00001739 51.0
HKD2_k127_9762749_42 Belongs to the peptidase S8 family K13276 GO:0005575,GO:0005576 - 0.0001533 51.0
HKD2_k127_9762749_43 Carboxypeptidase regulatory-like domain - - - 0.0002412 49.0
HKD2_k127_9762749_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 494.0
HKD2_k127_9762749_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 469.0
HKD2_k127_9762749_7 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 451.0
HKD2_k127_9762749_8 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 411.0
HKD2_k127_9762749_9 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 387.0
HKD2_k127_9926102_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.25e-237 740.0
HKD2_k127_9926102_1 Malate synthase K01638 - 2.3.3.9 1.326e-235 739.0
HKD2_k127_9926102_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 493.0
HKD2_k127_9926102_3 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 419.0
HKD2_k127_9926102_4 L-Lactate permease K03303 - - 0.0000000000000000000000000000000000000000000002426 168.0
HKD2_k127_9998279_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1923.0
HKD2_k127_9998279_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 619.0
HKD2_k127_9998279_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000001255 221.0
HKD2_k127_9998279_3 helix_turn_helix, mercury resistance K19591 - - 0.000000000006092 72.0