Overview

ID MAG01813
Name HKD2_bin.7
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Microgenomatia
Order GWA2-44-7
Family UBA8517
Genus
Species
Assembly information
Completeness (%) 87.46
Contamination (%) 3.43
GC content (%) 41.0
N50 (bp) 6,380
Genome size (bp) 890,039

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes799

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10000125_0 NACHT domain - - - 0.000000001545 70.0
HKD2_k127_1002444_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 325.0
HKD2_k127_1002444_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000001915 184.0
HKD2_k127_1002444_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000002825 156.0
HKD2_k127_1002444_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000002555 59.0
HKD2_k127_10038192_0 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000001646 159.0
HKD2_k127_10038192_1 Transglycosylase-like domain K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.00002035 53.0
HKD2_k127_10038192_2 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.0009923 43.0
HKD2_k127_10042713_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 445.0
HKD2_k127_10042713_1 inorganic diphosphatase activity K01507,K01514,K15986 - 3.6.1.1,3.6.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001726 260.0
HKD2_k127_10042713_2 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000002016 177.0
HKD2_k127_10042713_3 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000008591 145.0
HKD2_k127_10042713_4 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.00000000000000000000000000000000002457 145.0
HKD2_k127_10042713_5 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000001804 107.0
HKD2_k127_10042713_6 prohibitin homologues - - - 0.0001847 45.0
HKD2_k127_10112557_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.43e-200 647.0
HKD2_k127_10112557_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 383.0
HKD2_k127_10112557_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 338.0
HKD2_k127_10112557_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 299.0
HKD2_k127_10112557_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HKD2_k127_10112557_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000001786 177.0
HKD2_k127_10112557_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000002714 107.0
HKD2_k127_10167213_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.194e-218 696.0
HKD2_k127_10167213_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000003294 93.0
HKD2_k127_10183287_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000002232 170.0
HKD2_k127_10183287_1 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000151 81.0
HKD2_k127_10183287_2 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 0.00000000000006685 83.0
HKD2_k127_10183287_3 - - - - 0.0000000007259 72.0
HKD2_k127_1046060_0 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 337.0
HKD2_k127_1046060_1 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009699 255.0
HKD2_k127_1046060_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0001209 45.0
HKD2_k127_1055300_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00226,K00254,K02823,K17828 - 1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000004276 239.0
HKD2_k127_1055300_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000105 156.0
HKD2_k127_1055300_2 Enoyl-(Acyl carrier protein) reductase K00059,K04708 - 1.1.1.100,1.1.1.102 0.0000000000000000000001696 103.0
HKD2_k127_1067615_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000004248 198.0
HKD2_k127_1067615_1 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000002511 182.0
HKD2_k127_1067615_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000003456 161.0
HKD2_k127_1067615_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000001901 160.0
HKD2_k127_1067615_4 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000185 119.0
HKD2_k127_1067615_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000002744 119.0
HKD2_k127_1067615_6 - - - - 0.000003718 57.0
HKD2_k127_1345432_0 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
HKD2_k127_1345432_1 carboxylic ester hydrolase activity - - - 0.0000001454 56.0
HKD2_k127_1428905_0 seryl-tRNA aminoacylation K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 462.0
HKD2_k127_1428905_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 377.0
HKD2_k127_1428905_2 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000001029 229.0
HKD2_k127_1428905_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000003523 156.0
HKD2_k127_1428905_4 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000001973 127.0
HKD2_k127_1428905_5 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.00000000000000000000000000008619 124.0
HKD2_k127_1428905_6 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000001671 114.0
HKD2_k127_1428905_7 CYTH domain K05873 - 4.6.1.1 0.0000000000001075 79.0
HKD2_k127_1428905_8 EamA-like transporter family K08978 - - 0.0000006301 60.0
HKD2_k127_1435356_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 510.0
HKD2_k127_1435356_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0001844 51.0
HKD2_k127_1489544_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.376e-195 632.0
HKD2_k127_1489544_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 324.0
HKD2_k127_1489544_10 Protein of unknown function (DUF4012) - - - 0.000000006389 70.0
HKD2_k127_1489544_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000003861 56.0
HKD2_k127_1489544_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000224 48.0
HKD2_k127_1489544_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000914 249.0
HKD2_k127_1489544_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000004602 233.0
HKD2_k127_1489544_4 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000009257 129.0
HKD2_k127_1489544_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000316 117.0
HKD2_k127_1489544_6 hydrolase, P-loop family K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000005542 105.0
HKD2_k127_1489544_7 single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000002394 105.0
HKD2_k127_1489544_8 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000004251 95.0
HKD2_k127_1489544_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000002001 89.0
HKD2_k127_1494861_0 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
HKD2_k127_1494861_1 mRNA catabolic process K03646,K07456,K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000006364 128.0
HKD2_k127_1494861_2 Domain of unknown function (DUF1858) - - - 0.0001689 46.0
HKD2_k127_1541651_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 452.0
HKD2_k127_1541651_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000003296 99.0
HKD2_k127_1541651_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000001901 86.0
HKD2_k127_1541651_3 ATP synthase B/B' CF(0) K02109 - - 0.00001019 53.0
HKD2_k127_1551371_0 oligosaccharyl transferase activity K19003,K20327 - 2.4.1.336 0.0000000000000000000000000000000000000000000000000001898 197.0
HKD2_k127_1551371_1 - - - - 0.00000004173 65.0
HKD2_k127_1554062_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 431.0
HKD2_k127_1572086_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 507.0
HKD2_k127_1572086_1 Phenylalanyl-tRNA synthetase beta K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000004252 119.0
HKD2_k127_1788867_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000002363 174.0
HKD2_k127_1969108_0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 304.0
HKD2_k127_1969108_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 302.0
HKD2_k127_1969108_2 PFAM Arginine-tRNA-protein transferase, C terminus K21420 - 2.3.2.29 0.00000000000000000000000000638 118.0
HKD2_k127_2035650_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family K00694,K15531,K20542 - 2.4.1.12,3.2.1.156,3.2.1.4 0.000000000000000000000000000001285 130.0
HKD2_k127_2035650_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000009693 87.0
HKD2_k127_2035650_2 NUDIX domain K03574 - 3.6.1.55 0.0004793 45.0
HKD2_k127_2095987_0 Pilus assembly protein K02662,K02663,K12288 GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000001502 77.0
HKD2_k127_2124347_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 400.0
HKD2_k127_2124347_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002494 301.0
HKD2_k127_2124347_2 Glycosyl hydrolases family 8 K00694 - 2.4.1.12 0.000000000000000000000000000000000002 159.0
HKD2_k127_2146089_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 444.0
HKD2_k127_2146089_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000006076 98.0
HKD2_k127_2213235_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000006193 57.0
HKD2_k127_2213235_2 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00002729 53.0
HKD2_k127_2213235_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00009303 49.0
HKD2_k127_2213781_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
HKD2_k127_2213781_1 PFAM RNA recognition motif - - - 0.0000000000000000000000001656 109.0
HKD2_k127_2213781_3 Protein of unknown function (DUF3307) - - - 0.00009894 49.0
HKD2_k127_2286992_0 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000001335 214.0
HKD2_k127_2305047_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 422.0
HKD2_k127_2305047_1 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000003172 195.0
HKD2_k127_2305047_2 methyltransferase - - - 0.000000000000000000000000003594 119.0
HKD2_k127_2305047_3 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000006665 100.0
HKD2_k127_2305047_4 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000003976 107.0
HKD2_k127_2305047_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000001031 91.0
HKD2_k127_2305047_6 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - 0.0000000000000002928 91.0
HKD2_k127_2305047_7 O-Antigen ligase - - - 0.00005411 55.0
HKD2_k127_2320132_0 alpha-glucan phosphorylase K00688,K00691,K16153 - 2.4.1.1,2.4.1.11,2.4.1.8 0.0000000000000000000000000000000000000000000000002303 183.0
HKD2_k127_2320132_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000001321 70.0
HKD2_k127_2427548_0 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000001017 191.0
HKD2_k127_2465641_0 VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003127 233.0
HKD2_k127_2465641_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000009562 124.0
HKD2_k127_2627656_0 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 292.0
HKD2_k127_2627656_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000002302 131.0
HKD2_k127_2627656_2 Biotin carboxylase-like protein - - - 0.00000000000000000000000000004989 132.0
HKD2_k127_2627656_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000002999 104.0
HKD2_k127_2627656_4 NUDIX domain - - - 0.000000002129 64.0
HKD2_k127_2627656_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000005943 63.0
HKD2_k127_2627656_6 oxidoreductase activity - - - 0.0000001818 61.0
HKD2_k127_2627656_7 lysine biosynthesis protein LysW K05826 - - 0.0000007509 53.0
HKD2_k127_2755891_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 535.0
HKD2_k127_2755891_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00262 - 1.4.1.2,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 416.0
HKD2_k127_2755891_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 374.0
HKD2_k127_2755891_3 Belongs to the ClpA ClpB family K03695,K03696 - - 0.000000003727 68.0
HKD2_k127_276392_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.086e-234 751.0
HKD2_k127_276392_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 377.0
HKD2_k127_276392_10 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000007528 91.0
HKD2_k127_276392_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000008131 77.0
HKD2_k127_276392_12 PspC domain protein - - - 0.000000000000003447 76.0
HKD2_k127_276392_13 bacitracin transport permease K19302 - 3.6.1.27 0.00000000000003989 79.0
HKD2_k127_276392_14 - - - - 0.00000000000936 73.0
HKD2_k127_276392_15 - - - - 0.0000000162 59.0
HKD2_k127_276392_16 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000009605 52.0
HKD2_k127_276392_17 Haloacid dehalogenase-like hydrolase K20860 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043621,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0090711 3.1.3.102,3.1.3.104 0.0001013 51.0
HKD2_k127_276392_18 Sigma factors are initiation factors that promote the attachment of plastid-encoded RNA polymerase (PEP) to specific initiation sites and are then released K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006399,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009639,GO:0009657,GO:0009658,GO:0009889,GO:0009987,GO:0010114,GO:0010467,GO:0010468,GO:0010556,GO:0016043,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097659,GO:0104004,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0001228 47.0
HKD2_k127_276392_19 Phosphodiester glycosidase - - - 0.0005239 52.0
HKD2_k127_276392_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000001124 188.0
HKD2_k127_276392_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000054 171.0
HKD2_k127_276392_4 EamA-like transporter family K08978 - - 0.000000000000000000000000000000000000000004072 158.0
HKD2_k127_276392_6 - - - - 0.00000000000000000000000001201 112.0
HKD2_k127_276392_7 UDP kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000001487 109.0
HKD2_k127_276392_8 Zincin-like metallopeptidase - - - 0.0000000000000000000000003681 109.0
HKD2_k127_276392_9 NUDIX domain - - - 0.000000000000000004665 89.0
HKD2_k127_2780469_0 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
HKD2_k127_2780469_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000002421 93.0
HKD2_k127_2780469_2 tRNA-binding protein K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000815 54.0
HKD2_k127_2855710_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 332.0
HKD2_k127_2855710_1 inorganic diphosphatase activity K01507 - 3.6.1.1 0.00000000000000000000000000000000000003881 145.0
HKD2_k127_2855710_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000003597 106.0
HKD2_k127_2855710_3 - - - - 0.00000000000005363 83.0
HKD2_k127_2855710_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000005146 66.0
HKD2_k127_2855710_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000005438 59.0
HKD2_k127_2855710_6 - - - - 0.00000002563 63.0
HKD2_k127_2855710_7 - - - - 0.00004587 56.0
HKD2_k127_2929228_0 AAA domain - - - 0.0000000000000000000000000000000000000000001045 166.0
HKD2_k127_2929228_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000003739 154.0
HKD2_k127_2929228_10 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00004552 55.0
HKD2_k127_2929228_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000001096 134.0
HKD2_k127_2929228_3 Transglycosylase associated protein - - - 0.000000000000000000000000984 105.0
HKD2_k127_2929228_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000001821 107.0
HKD2_k127_2929228_5 - - - - 0.0000000000000007169 78.0
HKD2_k127_2929228_6 YGGT family - - - 0.0000000000168 69.0
HKD2_k127_2929228_7 Stress-induced bacterial acidophilic repeat motif - - - 0.00000000008007 64.0
HKD2_k127_2929228_8 Phospholipase/Carboxylesterase - - - 0.0000007823 60.0
HKD2_k127_2931730_0 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000000000000000000000000000001213 147.0
HKD2_k127_2931730_1 cell adhesion involved in biofilm formation - - - 0.0007138 50.0
HKD2_k127_2947258_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0000000006208 71.0
HKD2_k127_3143490_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 539.0
HKD2_k127_3143490_1 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 525.0
HKD2_k127_3143490_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000001148 67.0
HKD2_k127_3143490_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00008661 49.0
HKD2_k127_3143490_2 Uncharacterised protein family UPF0052 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000434 266.0
HKD2_k127_3143490_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000004407 261.0
HKD2_k127_3143490_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD2_k127_3143490_5 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000001028 244.0
HKD2_k127_3143490_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.0000000000000000000000000000003171 130.0
HKD2_k127_3143490_7 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000318 109.0
HKD2_k127_3143490_8 Yqey-like protein K09117 - - 0.00000000000000000001704 96.0
HKD2_k127_3143490_9 Putative tRNA binding domain K06878 - - 0.0000000000000003992 79.0
HKD2_k127_3191530_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 2.456e-291 924.0
HKD2_k127_3191530_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
HKD2_k127_3191530_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000009591 216.0
HKD2_k127_3191530_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000291 198.0
HKD2_k127_3191530_4 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000007642 124.0
HKD2_k127_3191530_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002594 81.0
HKD2_k127_3191530_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000669 78.0
HKD2_k127_3191530_7 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000002889 54.0
HKD2_k127_320119_0 PFAM TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 376.0
HKD2_k127_320119_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 249.0
HKD2_k127_320119_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000002371 168.0
HKD2_k127_320119_3 Tetratricopeptide repeat - - - 0.000000000000000000000000001014 121.0
HKD2_k127_320119_4 Molecular chaperone DnaK - - - 0.00001316 53.0
HKD2_k127_3229055_0 Type II/IV secretion system protein K02652,K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 336.0
HKD2_k127_3229055_1 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004561 264.0
HKD2_k127_3229055_2 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000009255 59.0
HKD2_k127_3229055_3 general secretion pathway protein K02456 - - 0.0008902 49.0
HKD2_k127_325839_0 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 552.0
HKD2_k127_325839_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
HKD2_k127_325839_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000008122 72.0
HKD2_k127_3380837_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.299e-231 732.0
HKD2_k127_3380837_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 286.0
HKD2_k127_3380837_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000004646 68.0
HKD2_k127_3395320_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000356 247.0
HKD2_k127_3395320_1 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000002301 62.0
HKD2_k127_3395320_3 Belongs to the UPF0306 family K09979 - - 0.0000001693 59.0
HKD2_k127_3395320_4 - - - - 0.0001645 51.0
HKD2_k127_3615126_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.221e-241 768.0
HKD2_k127_3615126_1 cellulose binding - - - 0.00000000004412 76.0
HKD2_k127_3652257_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 433.0
HKD2_k127_3652257_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000004745 173.0
HKD2_k127_3652257_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000004283 88.0
HKD2_k127_3652257_3 Putative tRNA binding domain K01866 - 6.1.1.1 0.000008339 52.0
HKD2_k127_3658975_0 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000008017 224.0
HKD2_k127_3658975_1 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.00000000000000000000003746 106.0
HKD2_k127_3658975_2 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 0.0000000000000000000002801 107.0
HKD2_k127_3658975_3 Ribosomal protein S6 modification K05844 - - 0.000000000000000000000989 106.0
HKD2_k127_3658975_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000001223 86.0
HKD2_k127_3658975_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000002371 82.0
HKD2_k127_3658975_6 Inactive transglutaminase fused to 7 transmembrane helices - - - 0.0000003604 57.0
HKD2_k127_3658975_7 PFAM Tetratricopeptide repeat - - - 0.00009158 55.0
HKD2_k127_3816728_0 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 296.0
HKD2_k127_3816728_1 LemA family K03744 - - 0.000000000000000000000000000000042 132.0
HKD2_k127_3816728_2 Major Facilitator Superfamily - - - 0.000000000000000000002745 106.0
HKD2_k127_3821026_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 541.0
HKD2_k127_3821026_1 ATP dependent DNA ligase C terminal region K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 402.0
HKD2_k127_3821026_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000003975 132.0
HKD2_k127_3990419_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02243,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 344.0
HKD2_k127_3990419_1 Methyltransferase domain - - - 0.00000000000000000000000000001243 127.0
HKD2_k127_3990419_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000008321 125.0
HKD2_k127_3990419_3 - - - - 0.000000002132 65.0
HKD2_k127_3990419_4 cell wall organization - - - 0.0000005795 59.0
HKD2_k127_3990419_5 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0001323 54.0
HKD2_k127_4005391_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000111 210.0
HKD2_k127_4005391_1 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000005729 149.0
HKD2_k127_4005391_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000005959 131.0
HKD2_k127_4005391_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000004797 105.0
HKD2_k127_4021080_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000002452 248.0
HKD2_k127_4021080_1 Ribonuclease H-like K09776 - - 0.000000000000000000000000000000000000001039 153.0
HKD2_k127_4021080_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000009563 113.0
HKD2_k127_4021080_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000004997 85.0
HKD2_k127_4021080_4 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0002314 52.0
HKD2_k127_4024298_0 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 544.0
HKD2_k127_4024298_1 lipolytic protein G-D-S-L family - - - 0.00000008575 63.0
HKD2_k127_4024298_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000808 55.0
HKD2_k127_4049690_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 497.0
HKD2_k127_4049690_1 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.000000000000000000000000000000000000000000000000000000000000001441 231.0
HKD2_k127_4049690_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000007689 203.0
HKD2_k127_4049690_3 Belongs to the MraZ family K03925 - - 0.000000000000000000000000009484 114.0
HKD2_k127_4049690_4 TspO/MBR family K05770 - - 0.00001483 47.0
HKD2_k127_4049690_5 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0004719 48.0
HKD2_k127_413439_0 Bacterial membrane protein YfhO - - - 0.000000000000000000005156 108.0
HKD2_k127_4153691_0 E1-E2 ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 497.0
HKD2_k127_4153691_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
HKD2_k127_4153691_2 Protein of unknown function (DUF2905) - - - 0.0000000000000000004848 88.0
HKD2_k127_4153691_3 Rhodanese Homology Domain - - - 0.00000000000000001719 95.0
HKD2_k127_4153691_4 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000002826 81.0
HKD2_k127_4153691_5 membrane protein (DUF2078) - - - 0.000000000000005528 82.0
HKD2_k127_4174095_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 507.0
HKD2_k127_4174095_1 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000006939 58.0
HKD2_k127_42018_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000009031 151.0
HKD2_k127_42018_1 Psort location CytoplasmicMembrane, score - - - 0.00000000001565 73.0
HKD2_k127_42018_2 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000002577 61.0
HKD2_k127_42018_3 Pfam:N_methyl_2 K02650 - - 0.00001808 52.0
HKD2_k127_4217353_0 glycoside hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 402.0
HKD2_k127_4217353_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 329.0
HKD2_k127_4217353_2 TIGRFAM tRNA-guanine transglycosylase, various specificities K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002122 263.0
HKD2_k127_4217353_3 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000008425 194.0
HKD2_k127_4217353_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000006551 184.0
HKD2_k127_4217353_5 Methionine biosynthesis protein MetW - - - 0.00000000000001477 81.0
HKD2_k127_4217353_6 cell envelope-related function transcriptional attenuator - - - 0.000002359 57.0
HKD2_k127_4262000_0 Short C-terminal domain K08982 - - 0.000000001412 61.0
HKD2_k127_4262000_1 - - - - 0.00003726 47.0
HKD2_k127_4262000_2 cell envelope-related function transcriptional attenuator - - - 0.0007534 50.0
HKD2_k127_4287056_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 370.0
HKD2_k127_4287056_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000682 144.0
HKD2_k127_4287056_2 PFAM Glycosyl transferase, family 2 K21304 GO:0003674,GO:0003824,GO:0016740 2.4.1.153 0.000000000000000000000000000000001195 138.0
HKD2_k127_4287056_3 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000008881 55.0
HKD2_k127_4321612_0 Glycosyltransferase like family 2 - - - 0.00000000000000007725 91.0
HKD2_k127_4321612_1 Glycosyl transferases group 1 - - - 0.0000000001887 73.0
HKD2_k127_4321612_2 Glycosyl transferase - - - 0.000000004589 64.0
HKD2_k127_4460934_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 388.0
HKD2_k127_4460934_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000001406 65.0
HKD2_k127_4460934_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000003616 55.0
HKD2_k127_4835273_0 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002384 277.0
HKD2_k127_4835273_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000001964 196.0
HKD2_k127_4835273_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000002271 128.0
HKD2_k127_4835273_3 Glycosyl transferase 4-like - - - 0.00000000000000000000000000007066 130.0
HKD2_k127_4835273_4 COG0463 Glycosyltransferases involved in cell wall biogenesis K00786 - - 0.000000000000000000000001261 112.0
HKD2_k127_4835273_5 - - - - 0.000000000000007556 78.0
HKD2_k127_4835273_7 Methyltransferase FkbM domain - - - 0.000000000008388 69.0
HKD2_k127_4835273_8 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000004914 62.0
HKD2_k127_48382_0 'Conserved protein K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000000006476 233.0
HKD2_k127_48382_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000005581 109.0
HKD2_k127_48382_2 PFAM NUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000003073 88.0
HKD2_k127_48382_3 Psort location CytoplasmicMembrane, score - - - 0.000000000000002018 84.0
HKD2_k127_48382_4 PFAM peptidase S51 dipeptidase E K05995 - 3.4.13.21 0.000000000346 69.0
HKD2_k127_48382_5 Acetyltransferase (GNAT) domain - - - 0.0000001017 57.0
HKD2_k127_4941564_0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000009327 172.0
HKD2_k127_4941564_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000001571 125.0
HKD2_k127_4941564_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000003048 88.0
HKD2_k127_5175655_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000337 188.0
HKD2_k127_5175655_1 AdoMet dependent proline di-methyltransferase - - - 0.0000000006397 68.0
HKD2_k127_5175655_2 Predicted membrane protein (DUF2207) - - - 0.0003157 46.0
HKD2_k127_5195872_0 InterPro IPR014922 - - - 0.000000000000000000000000000000000000000000000000001702 185.0
HKD2_k127_5195872_1 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000006601 104.0
HKD2_k127_5195872_4 - - - - 0.00000000000000000000004028 104.0
HKD2_k127_5195872_5 - - - - 0.0000000000000000001387 93.0
HKD2_k127_5220038_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
HKD2_k127_5220038_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000006356 176.0
HKD2_k127_5262707_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002871 238.0
HKD2_k127_5262707_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000003948 159.0
HKD2_k127_5275235_0 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 315.0
HKD2_k127_5275235_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000001483 198.0
HKD2_k127_5275235_2 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000008104 188.0
HKD2_k127_5275235_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000008397 189.0
HKD2_k127_5275235_4 S-adenosyl-l-methionine hydroxide adenosyltransferase - - - 0.00000000000000000008247 99.0
HKD2_k127_5275235_5 protein, YerC YecD - - - 0.00003086 51.0
HKD2_k127_5369870_0 RNHCP domain - - - 0.0000000000000000000000000503 112.0
HKD2_k127_5369870_1 Acetyltransferase (GNAT) domain K02348 - - 0.000135 51.0
HKD2_k127_54033_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1177.0
HKD2_k127_54033_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 3.802e-310 975.0
HKD2_k127_54033_10 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000009883 203.0
HKD2_k127_54033_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000003344 200.0
HKD2_k127_54033_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000003245 190.0
HKD2_k127_54033_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000002605 188.0
HKD2_k127_54033_14 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000002308 176.0
HKD2_k127_54033_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000001218 175.0
HKD2_k127_54033_16 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003604 173.0
HKD2_k127_54033_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000004131 173.0
HKD2_k127_54033_18 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000005148 160.0
HKD2_k127_54033_19 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000007706 157.0
HKD2_k127_54033_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.196e-260 820.0
HKD2_k127_54033_20 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000283 153.0
HKD2_k127_54033_21 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000006379 139.0
HKD2_k127_54033_22 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000005277 134.0
HKD2_k127_54033_23 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000005205 123.0
HKD2_k127_54033_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000008331 121.0
HKD2_k127_54033_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000002686 117.0
HKD2_k127_54033_26 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000498 123.0
HKD2_k127_54033_27 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000013 107.0
HKD2_k127_54033_28 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001233 110.0
HKD2_k127_54033_29 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000003764 96.0
HKD2_k127_54033_3 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 596.0
HKD2_k127_54033_30 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000005389 94.0
HKD2_k127_54033_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000003317 86.0
HKD2_k127_54033_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000005592 89.0
HKD2_k127_54033_33 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001035 86.0
HKD2_k127_54033_34 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000001181 85.0
HKD2_k127_54033_35 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000006584 81.0
HKD2_k127_54033_36 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004765 74.0
HKD2_k127_54033_37 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000004932 79.0
HKD2_k127_54033_38 Binds to the 23S rRNA K02876 - - 0.0000000000001589 76.0
HKD2_k127_54033_39 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000001551 68.0
HKD2_k127_54033_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 390.0
HKD2_k127_54033_40 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000004998 64.0
HKD2_k127_54033_41 Nudix hydrolase K03574 - 3.6.1.55 0.0001966 51.0
HKD2_k127_54033_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002987 274.0
HKD2_k127_54033_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000005946 253.0
HKD2_k127_54033_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000009781 239.0
HKD2_k127_54033_8 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.0000000000000000000000000000000000000000000000000000000003101 211.0
HKD2_k127_54033_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003234 204.0
HKD2_k127_5463624_0 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000000000000000000003512 137.0
HKD2_k127_5463624_1 DegT/DnrJ/EryC1/StrS aminotransferase family K02805 - 2.6.1.59 0.000000000000000386 89.0
HKD2_k127_5543133_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000003303 147.0
HKD2_k127_5543133_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000003237 57.0
HKD2_k127_5543133_2 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00008544 47.0
HKD2_k127_5543133_3 PFAM membrane protein of K08972 - - 0.0001924 49.0
HKD2_k127_5648597_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003054 247.0
HKD2_k127_5648597_1 Ribosomal RNA adenine dimethylase K00561 - 2.1.1.184 0.000000000000000000000000000000000000000005173 164.0
HKD2_k127_5665468_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 353.0
HKD2_k127_5665468_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
HKD2_k127_5665468_2 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000002287 196.0
HKD2_k127_5665468_3 Inositol monophosphatase family K10047,K13104 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006020,GO:0006021,GO:0006066,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009058,GO:0009108,GO:0009110,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010347,GO:0016020,GO:0016051,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019637,GO:0019751,GO:0019752,GO:0019852,GO:0019853,GO:0023052,GO:0034637,GO:0042364,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0043647,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046165,GO:0046173,GO:0046174,GO:0046364,GO:0046394,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050308,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0070456,GO:0071545,GO:0071704,GO:0071944,GO:0080167,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617 3.1.3.25,3.1.3.93 0.000000000000000000000000000000005082 138.0
HKD2_k127_5665468_4 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000001562 106.0
HKD2_k127_5665468_5 - - - - 0.000002702 50.0
HKD2_k127_5669175_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000006731 205.0
HKD2_k127_5669175_1 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000001224 210.0
HKD2_k127_5669175_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000008784 154.0
HKD2_k127_5669175_3 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000003326 156.0
HKD2_k127_5734589_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000006108 106.0
HKD2_k127_5734589_1 domain, Protein K09766 - - 0.0000000000008843 81.0
HKD2_k127_5734589_2 stage II sporulation protein K06381 - - 0.00000007366 65.0
HKD2_k127_5734589_3 - - - - 0.0001491 49.0
HKD2_k127_5743087_0 GTP1/OBG K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001863 275.0
HKD2_k127_5743087_1 Acetyltransferase (GNAT) domain - - - 0.000004491 55.0
HKD2_k127_5743087_2 PFAM Bacterial membrane flanked domain - - - 0.0001312 50.0
HKD2_k127_57782_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000001704 188.0
HKD2_k127_5793815_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.205e-196 621.0
HKD2_k127_5793815_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000002486 204.0
HKD2_k127_5793815_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000007858 196.0
HKD2_k127_5793815_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000001003 142.0
HKD2_k127_5793815_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000005382 101.0
HKD2_k127_5793815_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000001159 91.0
HKD2_k127_5809901_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 428.0
HKD2_k127_5809901_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002 268.0
HKD2_k127_5809901_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000592 164.0
HKD2_k127_5809901_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000001931 156.0
HKD2_k127_5809901_4 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000001341 134.0
HKD2_k127_5809901_5 acetyl coenzyme A synthetase K01905,K22224 - 6.2.1.13 0.00000000000000000001389 104.0
HKD2_k127_5809901_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000006364 84.0
HKD2_k127_5809901_7 - - - - 0.000000000000008489 83.0
HKD2_k127_5809901_8 4Fe-4S single cluster domain K05337 - - 0.0000000162 59.0
HKD2_k127_5809901_9 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000987 48.0
HKD2_k127_5815285_0 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 418.0
HKD2_k127_5815285_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly permease and ATPase components K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005231 258.0
HKD2_k127_5815285_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005882 256.0
HKD2_k127_5815285_3 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.0000000000000000000000000000000000002379 147.0
HKD2_k127_5815285_4 membrane - - - 0.0000000000000000007868 95.0
HKD2_k127_5815285_5 Major Facilitator - - - 0.000000000000000001029 98.0
HKD2_k127_5815285_6 serine-type peptidase activity - - - 0.00000436 52.0
HKD2_k127_5857045_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 344.0
HKD2_k127_5857045_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000594 62.0
HKD2_k127_5857045_2 Siderophore-interacting FAD-binding domain - - - 0.0007487 45.0
HKD2_k127_5877430_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000139 233.0
HKD2_k127_5877430_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000002402 180.0
HKD2_k127_5877430_2 Cupin domain - - - 0.000000000000000000000000000007229 122.0
HKD2_k127_5877430_3 Rhodanese-like protein - - - 0.00000000000000000114 89.0
HKD2_k127_5877430_4 Glyoxalase-like domain - - - 0.0000000000000001723 84.0
HKD2_k127_5877430_5 Glutaredoxin - - - 0.0000000000002995 73.0
HKD2_k127_5877430_6 Protein of unknown function (DUF2892) - - - 0.0000000000006563 70.0
HKD2_k127_5877430_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000578 54.0
HKD2_k127_5877430_8 Peptidase, M23 - - - 0.0001645 51.0
HKD2_k127_5953361_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002795 258.0
HKD2_k127_5953361_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000005184 76.0
HKD2_k127_5953361_2 ABC transporter K06158 - - 0.0008264 43.0
HKD2_k127_6005707_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 1.706e-265 852.0
HKD2_k127_6005707_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000008694 91.0
HKD2_k127_6032681_0 COG1994 Zn-dependent proteases - - - 0.000000000000000000000000000000000000000004341 162.0
HKD2_k127_6032681_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000006239 148.0
HKD2_k127_6032681_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000002562 121.0
HKD2_k127_6032681_3 Bacterial capsule synthesis protein PGA_cap K07282,K12132 - 2.7.11.1 0.000000000003663 67.0
HKD2_k127_6032681_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000007294 54.0
HKD2_k127_6032681_5 Tetratricopeptide repeat - - - 0.00003397 55.0
HKD2_k127_6032681_6 domain, Protein - - - 0.0005953 46.0
HKD2_k127_6128799_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 537.0
HKD2_k127_6128799_1 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 459.0
HKD2_k127_6128799_2 Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000001786 219.0
HKD2_k127_6128799_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000006896 210.0
HKD2_k127_6128799_4 TRANSCRIPTIONal - - - 0.000000000000000000000000000000003787 143.0
HKD2_k127_6128799_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000003133 85.0
HKD2_k127_6128799_6 NUDIX domain K01823 - 5.3.3.2 0.0000001343 59.0
HKD2_k127_6128799_7 Fibronectin type 3 domain - - - 0.0003797 52.0
HKD2_k127_6163033_0 Permeases of the major facilitator superfamily K08153 - - 0.0000000006271 65.0
HKD2_k127_6163033_1 Protein of unknown function (DUF1045) - - - 0.00001879 54.0
HKD2_k127_6247873_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 327.0
HKD2_k127_6247873_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000003402 119.0
HKD2_k127_630344_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.344e-204 649.0
HKD2_k127_630344_1 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000003714 162.0
HKD2_k127_630344_2 ABC transporter substrate-binding protein - - - 0.0000000000000000000000001809 121.0
HKD2_k127_630344_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000001016 100.0
HKD2_k127_630344_4 VanW like protein K18346 - - 0.00000002049 64.0
HKD2_k127_6360281_0 Flavodoxin domain - - - 0.0000000000000000000000000003797 117.0
HKD2_k127_6360281_1 Hep Hag repeat protein - - - 0.000001187 60.0
HKD2_k127_6360281_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00005332 52.0
HKD2_k127_6360281_3 O-Antigen ligase - - - 0.00008641 54.0
HKD2_k127_6397527_0 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000004098 141.0
HKD2_k127_6397527_1 - - - - 0.00000008916 63.0
HKD2_k127_6418790_0 Glycosyltransferase like family 2 K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000001033 196.0
HKD2_k127_6418790_1 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000000000009004 175.0
HKD2_k127_6418790_2 PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase - - - 0.00000000000007306 84.0
HKD2_k127_6418790_3 PFAM O-antigen polymerase K18814 - - 0.00026 50.0
HKD2_k127_6419292_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 404.0
HKD2_k127_6419292_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000512 153.0
HKD2_k127_6419292_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000506 98.0
HKD2_k127_6419292_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000003669 55.0
HKD2_k127_6419292_4 WxcM-like, C-terminal - - - 0.0000001511 60.0
HKD2_k127_6449436_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.066e-243 779.0
HKD2_k127_6449436_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000003053 151.0
HKD2_k127_647741_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 336.0
HKD2_k127_647741_1 Phosphoglycerate kinase K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000005408 167.0
HKD2_k127_647741_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000002701 102.0
HKD2_k127_647741_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000002913 62.0
HKD2_k127_6509472_0 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 331.0
HKD2_k127_6509472_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase - - - 0.00000000000000000000000000208 117.0
HKD2_k127_6509472_2 Domain of unknown function (DUF4342) - - - 0.0000000000000000009058 88.0
HKD2_k127_6509472_3 NUDIX domain - - - 0.0001643 51.0
HKD2_k127_6522946_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 376.0
HKD2_k127_6522946_1 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 311.0
HKD2_k127_6522946_2 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000007312 191.0
HKD2_k127_6522946_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000004228 82.0
HKD2_k127_6522946_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000007976 48.0
HKD2_k127_6529299_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000001268 265.0
HKD2_k127_6529299_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000004004 192.0
HKD2_k127_6529299_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000004796 150.0
HKD2_k127_6529299_3 FR47-like protein - - - 0.000000000000000000000199 103.0
HKD2_k127_6699696_0 Ham1 family - - - 0.00000000000000000000000000000000000000000002929 167.0
HKD2_k127_6699696_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000001155 134.0
HKD2_k127_6699696_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000003129 79.0
HKD2_k127_6699696_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000001029 73.0
HKD2_k127_6701660_0 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000002944 190.0
HKD2_k127_6701660_1 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000004985 187.0
HKD2_k127_6701660_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000119 93.0
HKD2_k127_6701660_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000002107 93.0
HKD2_k127_6701660_4 Belongs to the peptidase M16 family K07263 - - 0.00000009556 58.0
HKD2_k127_6701660_5 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.00001564 56.0
HKD2_k127_6701660_6 Belongs to the small heat shock protein (HSP20) family K13993 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001298 49.0
HKD2_k127_6701679_0 PFAM Elongation factor Tu domain 2 K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 613.0
HKD2_k127_6701679_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 582.0
HKD2_k127_6701679_2 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002918 251.0
HKD2_k127_6701679_3 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000002204 228.0
HKD2_k127_6701679_4 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group K01951 - 6.3.5.2 0.000000000000003323 85.0
HKD2_k127_6722564_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 549.0
HKD2_k127_6722564_1 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 372.0
HKD2_k127_6722564_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000002156 113.0
HKD2_k127_6722564_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000000005577 121.0
HKD2_k127_6722564_4 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000001377 78.0
HKD2_k127_6751253_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.353e-266 849.0
HKD2_k127_6751253_1 ABC transporter K06147,K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003773 286.0
HKD2_k127_6751253_2 Major Facilitator Superfamily - - - 0.00000000000000000008284 102.0
HKD2_k127_6751253_3 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000006346 86.0
HKD2_k127_6751253_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00001808 52.0
HKD2_k127_6751253_5 EamA-like transporter family - - - 0.00002447 55.0
HKD2_k127_6787588_0 Belongs to the D-alanine--D-alanine ligase family - - - 0.000000003147 69.0
HKD2_k127_6787588_1 peptidase dimerisation domain protein - - - 0.0000006789 51.0
HKD2_k127_6811561_0 glycine biosynthetic process from serine K00600 GO:0001505,GO:0002082,GO:0002376,GO:0003674,GO:0003682,GO:0003824,GO:0004372,GO:0004793,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0005759,GO:0005856,GO:0006082,GO:0006140,GO:0006417,GO:0006464,GO:0006508,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0008732,GO:0009058,GO:0009069,GO:0009070,GO:0009295,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010608,GO:0015630,GO:0016020,GO:0016043,GO:0016053,GO:0016579,GO:0016597,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019264,GO:0019538,GO:0019752,GO:0019842,GO:0019866,GO:0022607,GO:0030170,GO:0031090,GO:0031323,GO:0031326,GO:0031406,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032268,GO:0032991,GO:0034097,GO:0034248,GO:0034340,GO:0034641,GO:0036094,GO:0036211,GO:0042127,GO:0042133,GO:0042136,GO:0042221,GO:0042325,GO:0042558,GO:0042645,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043436,GO:0043457,GO:0043467,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045087,GO:0046394,GO:0046483,GO:0046653,GO:0046655,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051174,GO:0051186,GO:0051246,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070129,GO:0070279,GO:0070536,GO:0070552,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0097159,GO:1900542,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903578,GO:1903715,GO:2000112 2.1.2.1 0.00000000000000000000000000000000000000000000000000001222 194.0
HKD2_k127_6811561_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000001238 145.0
HKD2_k127_6811561_2 deoxynucleoside kinase K15519 - 2.7.1.74,2.7.1.76 0.0000000004939 72.0
HKD2_k127_6811561_3 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000008086 68.0
HKD2_k127_6837265_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000004464 201.0
HKD2_k127_6837265_1 Domain of unknown function (DUF4976) - - - 0.00001145 50.0
HKD2_k127_6864354_0 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000007849 146.0
HKD2_k127_6864354_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000008438 127.0
HKD2_k127_6864354_2 Belongs to the UPF0235 family K09131 - - 0.00000109 53.0
HKD2_k127_6930772_0 histidine kinase A domain protein - - - 0.0000000000000000000000002319 109.0
HKD2_k127_6930772_1 helix_turn_helix, mercury resistance - - - 0.00002032 48.0
HKD2_k127_6939438_0 HD domain K07023 - - 0.000000000000000000000000001323 119.0
HKD2_k127_6939438_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000002487 111.0
HKD2_k127_6939438_2 NUDIX domain - - - 0.0000000000000000007956 93.0
HKD2_k127_6939438_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000009992 56.0
HKD2_k127_6939438_4 sequence-specific DNA binding - - - 0.0000076 51.0
HKD2_k127_6953485_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 460.0
HKD2_k127_6953485_1 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000022 216.0
HKD2_k127_6958984_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000001365 149.0
HKD2_k127_6958984_1 Probably functions as a manganese efflux pump - - - 0.00000000000000003542 95.0
HKD2_k127_6959951_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 433.0
HKD2_k127_6959951_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000006235 179.0
HKD2_k127_6961044_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 518.0
HKD2_k127_6961044_1 ABC transporter substrate-binding protein K02016 - - 0.000000000928 64.0
HKD2_k127_6961044_2 Protein conserved in bacteria K15539 - - 0.0000006885 59.0
HKD2_k127_6971013_0 Psort location Cytoplasmic, score 9.97 K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000007416 253.0
HKD2_k127_6971013_1 Putative tRNA binding domain - - - 0.00000000000000000000000000000000000000000002284 164.0
HKD2_k127_6971013_2 - - - - 0.0000000000000000000000000000001776 138.0
HKD2_k127_6971013_3 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000001892 90.0
HKD2_k127_6971013_4 - - - - 0.0000000000002031 82.0
HKD2_k127_7021016_0 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000002251 231.0
HKD2_k127_7021016_1 Tetratricopeptide repeat - - - 0.000178 53.0
HKD2_k127_7072338_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 309.0
HKD2_k127_7072338_1 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000006813 177.0
HKD2_k127_7072338_2 Mannose-6-phosphate isomerase K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000188 172.0
HKD2_k127_7072338_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000001606 149.0
HKD2_k127_7072338_4 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000137 127.0
HKD2_k127_7072338_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000004894 111.0
HKD2_k127_7072338_6 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000004575 106.0
HKD2_k127_7148951_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000001636 222.0
HKD2_k127_7148951_1 - - - - 0.00000006991 61.0
HKD2_k127_7148951_2 Participates in both transcription termination and antitermination K02600 - - 0.00000015 58.0
HKD2_k127_7149286_0 Isopentenyl transferase K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000008998 201.0
HKD2_k127_7149286_1 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000007259 149.0
HKD2_k127_7149286_2 ABC-2 family transporter protein K01992 - - 0.0000003344 55.0
HKD2_k127_7149286_3 NUDIX domain - - - 0.0001157 50.0
HKD2_k127_7206651_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 334.0
HKD2_k127_7206651_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 300.0
HKD2_k127_7214002_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.000000000000000002902 97.0
HKD2_k127_7214002_1 - - - - 0.000002251 55.0
HKD2_k127_7402397_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000003856 244.0
HKD2_k127_7402397_1 diguanylate cyclase activity K02488 - 2.7.7.65 0.0000000000000000000000000000000000002979 158.0
HKD2_k127_7435440_0 GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 325.0
HKD2_k127_7435440_1 TRANSCRIPTIONal - - - 0.00000000000000000000000000000009131 137.0
HKD2_k127_7435440_2 spermidine synthase activity K18787 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0009888,GO:0009914,GO:0009926,GO:0009987,GO:0010087,GO:0010089,GO:0010487,GO:0010817,GO:0016740,GO:0016765,GO:0016768,GO:0030154,GO:0032502,GO:0044424,GO:0044464,GO:0048759,GO:0048856,GO:0048869,GO:0051179,GO:0051234,GO:0060918,GO:0065007,GO:0065008,GO:1905177 2.5.1.79 0.000000000000000003452 91.0
HKD2_k127_7435440_3 NUDIX domain - - - 0.00000005086 61.0
HKD2_k127_7435440_4 NUDIX domain K03574 - 3.6.1.55 0.0000003261 59.0
HKD2_k127_7435440_5 - - - - 0.000004436 49.0
HKD2_k127_7489426_0 Type IV secretory pathway, VirB4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 412.0
HKD2_k127_7489426_2 membrane - - - 0.0000154 58.0
HKD2_k127_755333_0 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002103 286.0
HKD2_k127_755333_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.13 0.00000000000000000000000000000000000000000001054 175.0
HKD2_k127_755333_2 Methicillin resistance protein - - - 0.000000000002452 69.0
HKD2_k127_755333_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000002806 56.0
HKD2_k127_765187_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 3.382e-220 698.0
HKD2_k127_765187_1 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000001627 171.0
HKD2_k127_765187_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000324 94.0
HKD2_k127_765187_3 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000001933 85.0
HKD2_k127_765187_4 - - - - 0.00000000000002488 79.0
HKD2_k127_765187_5 - - - - 0.0000000000454 72.0
HKD2_k127_765187_6 pathogenesis K21471,K21687 - - 0.00004159 53.0
HKD2_k127_7700379_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000001422 176.0
HKD2_k127_7723619_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 534.0
HKD2_k127_7723619_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001972 245.0
HKD2_k127_7723619_10 - - - - 0.0001441 53.0
HKD2_k127_7723619_11 Septum formation initiator K13052 - - 0.0001752 49.0
HKD2_k127_7723619_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002387 248.0
HKD2_k127_7723619_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000009561 238.0
HKD2_k127_7723619_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000006561 199.0
HKD2_k127_7723619_5 Methyltransferase FkbM domain - - - 0.0000000000000000000000000464 112.0
HKD2_k127_7723619_6 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000002159 117.0
HKD2_k127_7723619_7 tRNA-binding protein K06878 - - 0.0000000000000001156 85.0
HKD2_k127_7723619_8 Type IV secretion-system coupling protein DNA-binding domain - - - 0.000000000000001474 80.0
HKD2_k127_7723619_9 - - - - 0.00000000000008987 74.0
HKD2_k127_7818243_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 346.0
HKD2_k127_7818243_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K01343,K02111 - 3.4.21.68,3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 329.0
HKD2_k127_7833281_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 388.0
HKD2_k127_7833281_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 312.0
HKD2_k127_7833281_2 ATP synthase K02114 - - 0.0002564 48.0
HKD2_k127_7833281_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0004875 51.0
HKD2_k127_7976898_0 Glycosyl hydrolases family 15 K07190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
HKD2_k127_7976898_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000001757 229.0
HKD2_k127_7976898_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000009708 125.0
HKD2_k127_7976898_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000001203 115.0
HKD2_k127_7976898_4 cheY-homologous receiver domain K07658 - - 0.000000000000000002551 89.0
HKD2_k127_7976898_5 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.000000000000009275 83.0
HKD2_k127_7976898_6 Signal peptidase I K13280 - 3.4.21.89 0.0000000002274 70.0
HKD2_k127_7976898_7 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000107 61.0
HKD2_k127_7976898_8 ATP cone domain - - - 0.0001884 47.0
HKD2_k127_7976898_9 Phosphodiester glycosidase - - - 0.000402 51.0
HKD2_k127_8015369_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 599.0
HKD2_k127_8015369_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 392.0
HKD2_k127_8015369_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 317.0
HKD2_k127_8015369_3 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001353 255.0
HKD2_k127_8015369_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000003611 169.0
HKD2_k127_8015369_5 Mazg nucleotide pyrophosphohydrolase - - - 0.000000000000000000000000000000007978 130.0
HKD2_k127_8015369_6 O-Antigen ligase - - - 0.000000000001114 80.0
HKD2_k127_8015638_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000149 255.0
HKD2_k127_8015638_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000003348 248.0
HKD2_k127_8015638_10 Glycosyl transferase family 2 - - - 0.000000001443 68.0
HKD2_k127_8015638_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000007687 203.0
HKD2_k127_8015638_3 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000001108 177.0
HKD2_k127_8015638_4 Sulfatase - - - 0.00000000000000000000000000009662 132.0
HKD2_k127_8015638_5 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000008796 116.0
HKD2_k127_8015638_6 Sulfatase - - - 0.00000000000000000000001481 115.0
HKD2_k127_8015638_7 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000001672 115.0
HKD2_k127_8015638_8 arylsulfatase activity K01133 - 3.1.6.6 0.0000000000000000000003711 111.0
HKD2_k127_8015638_9 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000006988 98.0
HKD2_k127_8036513_0 Ribosomal protein S16 K02959 - - 0.000000000000000009756 84.0
HKD2_k127_8036513_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000008892 77.0
HKD2_k127_8036513_2 Belongs to the UPF0109 family K06960 - - 0.00002133 50.0
HKD2_k127_8114011_0 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000002146 233.0
HKD2_k127_8114011_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000009917 231.0
HKD2_k127_8114011_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000007282 209.0
HKD2_k127_8114011_3 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000009346 151.0
HKD2_k127_8114011_4 NUDIX domain K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000009274 96.0
HKD2_k127_8114011_5 Psort location Cytoplasmic, score 8.96 - - - 0.0000000001032 70.0
HKD2_k127_8114011_6 NUDIX domain K01823 - 5.3.3.2 0.000000237 53.0
HKD2_k127_8114011_7 Predicted permease K07089 - - 0.00002978 52.0
HKD2_k127_8175867_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 327.0
HKD2_k127_8175867_1 VanZ like family - - - 0.00000000000002488 79.0
HKD2_k127_8175867_2 Psort location Extracellular, score K21471 - - 0.00000001376 66.0
HKD2_k127_8175867_3 Lamin Tail Domain - - - 0.00008324 53.0
HKD2_k127_8208693_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000001083 109.0
HKD2_k127_8208693_1 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000009952 87.0
HKD2_k127_8208693_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000001794 83.0
HKD2_k127_8208693_3 NUDIX domain - - - 0.000000000009946 74.0
HKD2_k127_8208693_4 Carbon-nitrogen hydrolase K11206 - - 0.000000003432 67.0
HKD2_k127_8208693_5 - - - - 0.000000146 55.0
HKD2_k127_8208693_6 Mycolic acid cyclopropane synthetase - - - 0.0001409 46.0
HKD2_k127_8268991_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 564.0
HKD2_k127_8268991_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000004871 229.0
HKD2_k127_8268991_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000008475 96.0
HKD2_k127_8268991_3 sptr d1c427 - - - 0.00000000000001159 88.0
HKD2_k127_8268991_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000005709 66.0
HKD2_k127_8268991_5 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.0000000008167 68.0
HKD2_k127_8268991_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000006002 59.0
HKD2_k127_8274364_0 PFAM type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 418.0
HKD2_k127_8274364_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 338.0
HKD2_k127_8274364_10 Nucleotidyltransferase domain - - - 0.00000000000000000001619 99.0
HKD2_k127_8274364_11 Protein of unknown function (DUF4446) - - - 0.000000000000001553 83.0
HKD2_k127_8274364_12 - - - - 0.00000002672 55.0
HKD2_k127_8274364_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
HKD2_k127_8274364_3 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000003175 203.0
HKD2_k127_8274364_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000003046 195.0
HKD2_k127_8274364_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000002402 180.0
HKD2_k127_8274364_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000001266 163.0
HKD2_k127_8274364_7 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000005699 158.0
HKD2_k127_8274364_8 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000007828 128.0
HKD2_k127_8274364_9 PolyA polymerase K00974 - 2.7.7.72 0.000000000000000000000000002423 118.0
HKD2_k127_828916_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 317.0
HKD2_k127_8332109_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 351.0
HKD2_k127_8332109_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005388 245.0
HKD2_k127_8332109_2 - - - - 0.0000000000000000005031 94.0
HKD2_k127_8332109_3 Glutaredoxin - - - 0.00000000000003768 75.0
HKD2_k127_8332109_4 S-layer homology domain - - - 0.00000000002488 70.0
HKD2_k127_8332109_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0002688 44.0
HKD2_k127_8335147_0 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000008998 196.0
HKD2_k127_8335147_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000003915 171.0
HKD2_k127_8335147_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000002355 163.0
HKD2_k127_8335147_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000002841 70.0
HKD2_k127_8691202_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009599 282.0
HKD2_k127_8691202_1 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000001794 168.0
HKD2_k127_8691202_2 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000007207 102.0
HKD2_k127_8691202_3 membrane protein (DUF2207) - - - 0.00000000000001499 85.0
HKD2_k127_8691202_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000001387 68.0
HKD2_k127_8691202_5 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000197 57.0
HKD2_k127_8706359_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 1.183e-198 625.0
HKD2_k127_8706359_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000001969 132.0
HKD2_k127_8706359_2 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K07033,K09015 - - 0.0000000000000000000000000005067 120.0
HKD2_k127_8865572_0 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000001156 218.0
HKD2_k127_8865572_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000002209 213.0
HKD2_k127_8865572_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000003311 95.0
HKD2_k127_8953211_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 312.0
HKD2_k127_8953211_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 301.0
HKD2_k127_8953211_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000009801 169.0
HKD2_k127_8953211_3 - - - - 0.00000000000000000000000000000000002647 144.0
HKD2_k127_8967984_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.833e-220 713.0
HKD2_k127_8967984_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 512.0
HKD2_k127_8967984_2 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 449.0
HKD2_k127_8967984_3 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002353 268.0
HKD2_k127_8967984_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000317 160.0
HKD2_k127_8967984_6 Cob(I)yrinic acid a c-diamide adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000007056 139.0
HKD2_k127_8967984_7 CAAX protease self-immunity K07052 - - 0.00000003397 63.0
HKD2_k127_8967984_8 Ribonuclease HI K03469,K06993 - 3.1.26.4 0.0003516 49.0
HKD2_k127_8969560_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HKD2_k127_8969560_1 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 304.0
HKD2_k127_8969560_2 Thioredoxin - - - 0.0000000000000000000000000000000000002209 151.0
HKD2_k127_8969560_3 Thioredoxin K03671 - - 0.000000000000000000000000000000006094 130.0
HKD2_k127_8969560_4 PFAM SpoU rRNA Methylase family - - - 0.0000000000000000000000000000001377 130.0
HKD2_k127_8969560_5 Phosphoglycerate mutase family - - - 0.0000008828 58.0
HKD2_k127_8987369_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000286 190.0
HKD2_k127_8987369_1 pilus assembly protein K02662 - - 0.000000000000000000000000000000001908 142.0
HKD2_k127_8987369_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000001403 89.0
HKD2_k127_8987369_3 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003759 74.0
HKD2_k127_8987369_4 Belongs to the UPF0109 family K06960 - - 0.0000004346 54.0
HKD2_k127_9098524_0 Belongs to the HMG-CoA reductase family K00021 GO:0003674,GO:0003824,GO:0004420,GO:0006629,GO:0006694,GO:0006720,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
HKD2_k127_9098524_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
HKD2_k127_9098524_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 370.0
HKD2_k127_9098524_3 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000002219 201.0
HKD2_k127_9098524_4 PFAM GHMP kinase K00869 - 2.7.1.36 0.00000000000000000000000000002686 129.0
HKD2_k127_9098524_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000004595 121.0
HKD2_k127_9098524_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000001886 55.0
HKD2_k127_9208964_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 524.0
HKD2_k127_9208964_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001539 183.0
HKD2_k127_9208964_2 Enolase, N-terminal domain K01689 - 4.2.1.11 0.000000000000000000000000002431 113.0
HKD2_k127_9244237_0 Type II secretion system K02653 - - 0.000000000000000000000000003202 119.0
HKD2_k127_9244237_1 Pilus assembly protein PilX K02673 - - 0.00000000000864 78.0
HKD2_k127_9244237_2 pilus assembly protein PilW - - - 0.0001574 51.0
HKD2_k127_9245715_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 411.0
HKD2_k127_9245715_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 373.0
HKD2_k127_9245715_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000412 254.0
HKD2_k127_9245715_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000002782 89.0
HKD2_k127_9266_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003075 274.0
HKD2_k127_9266_1 Polysaccharide biosynthesis protein - - - 0.00000000008337 76.0
HKD2_k127_9266_2 transferase activity, transferring glycosyl groups K19003,K20327 - 2.4.1.336 0.0000000004366 74.0
HKD2_k127_9266_3 Glycosyl transferase family group 2 - - - 0.0000000007579 70.0
HKD2_k127_945537_0 COGs COG1914 Mn2 and Fe2 transporter of the NRAMP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 381.0
HKD2_k127_945537_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001354 266.0
HKD2_k127_945537_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000008239 107.0
HKD2_k127_945537_3 adenylate kinase activity K00858,K00939,K00944 - 2.7.1.23,2.7.4.10,2.7.4.3 0.0000000007253 70.0
HKD2_k127_9630102_0 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 363.0
HKD2_k127_9630102_1 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 352.0
HKD2_k127_9630102_2 pfkB family carbohydrate kinase - - - 0.000000000000000002614 96.0
HKD2_k127_9630102_3 Immunoglobulin-like domain of bacterial spore germination - - - 0.0000000001472 72.0
HKD2_k127_9674622_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 591.0
HKD2_k127_9674622_1 Ribosomal RNA adenine dimethylase - - - 0.00000007105 62.0
HKD2_k127_9721462_0 PFAM malic K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 477.0
HKD2_k127_9721462_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 334.0
HKD2_k127_9721462_2 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000001537 149.0
HKD2_k127_9721462_3 - - - - 0.0000000000000000005994 89.0
HKD2_k127_9721462_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000004897 83.0
HKD2_k127_9721462_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000003685 64.0
HKD2_k127_9755894_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 500.0
HKD2_k127_9755894_1 Methicillin resistance protein - - - 0.000000000000000000000000000000007261 131.0
HKD2_k127_9755894_2 NUDIX domain - - - 0.000000000000000000000000000004534 124.0
HKD2_k127_9755894_3 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000001552 93.0
HKD2_k127_9755894_4 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000006333 65.0
HKD2_k127_9755894_5 FemAB family - - - 0.000000003324 68.0
HKD2_k127_9755894_6 Domain of Unknown Function with PDB structure (DUF3850) - - - 0.0000000041 61.0
HKD2_k127_9757433_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 523.0
HKD2_k127_9757433_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 345.0
HKD2_k127_9757433_2 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 292.0
HKD2_k127_9757433_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 297.0
HKD2_k127_9757433_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000402 209.0
HKD2_k127_9757433_5 FMN binding - - - 0.0000000000000000000000000000002579 129.0
HKD2_k127_9757433_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000002989 109.0
HKD2_k127_9780684_0 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000001782 147.0
HKD2_k127_9780684_1 integral membrane protein K00728 - 2.4.1.109 0.00000000000000000000003321 113.0
HKD2_k127_9780684_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000005467 83.0
HKD2_k127_9803573_0 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.0000000000000000000000000000000000109 138.0
HKD2_k127_9829845_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 365.0
HKD2_k127_9829845_1 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000003925 58.0
HKD2_k127_9829845_2 Insulinase (Peptidase family M16) K07263 - - 0.0008318 51.0
HKD2_k127_9859563_0 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 345.0
HKD2_k127_9859563_1 biosynthesis glycosyltransferase K12984 - - 0.00000000000000000000000000000000000001593 155.0
HKD2_k127_9859563_2 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.000000000000000000000001208 113.0
HKD2_k127_9859563_3 PFAM glycosyl transferase family 39 - - - 0.0000000004455 70.0
HKD2_k127_99173_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 5.169e-223 725.0
HKD2_k127_99173_1 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000000000008182 104.0
HKD2_k127_9958117_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02243,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 295.0
HKD2_k127_9958117_1 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000001553 104.0
HKD2_k127_9958117_2 Conserved TM helix - - - 0.000000000000000001824 94.0
HKD2_k127_9973739_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 445.0
HKD2_k127_9973739_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000009009 196.0
HKD2_k127_9973739_10 metal-dependent phosphohydrolase, HD sub domain - - - 0.0003633 50.0
HKD2_k127_9973739_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000003848 193.0
HKD2_k127_9973739_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000001854 141.0
HKD2_k127_9973739_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000001446 111.0
HKD2_k127_9973739_5 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000145 105.0
HKD2_k127_9973739_6 Domain of unknown function (DUF4870) - - - 0.00000000000000001109 86.0
HKD2_k127_9973739_7 Transcriptional regulatory protein, C terminal K18144 - - 0.00008904 55.0
HKD2_k127_9973739_8 Alpha/beta hydrolase family - - - 0.0001698 50.0
HKD2_k127_9973739_9 Psort location Cytoplasmic, score 8.87 - - - 0.0003516 49.0
HKD2_k127_9973902_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000001238 129.0