Overview

ID MAG01815
Name HKD2_bin.71
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Hyphomicrobiaceae
Genus Hyphomicrobium_A
Species Hyphomicrobium_A sp035517115
Assembly information
Completeness (%) 89.3
Contamination (%) 1.85
GC content (%) 66.0
N50 (bp) 13,028
Genome size (bp) 2,661,978

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2491

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10008238_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1172.0
HKD2_k127_10008238_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 1.871e-236 741.0
HKD2_k127_10008238_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 581.0
HKD2_k127_10008238_3 DnaJ C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
HKD2_k127_102258_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 359.0
HKD2_k127_102258_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 316.0
HKD2_k127_102258_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002384 265.0
HKD2_k127_102258_3 Periplasmic protein thiol disulfide oxidoreductase K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000002409 246.0
HKD2_k127_102258_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000002753 217.0
HKD2_k127_102258_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000005157 68.0
HKD2_k127_107928_0 aminopeptidase N K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1273.0
HKD2_k127_107928_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1189.0
HKD2_k127_107928_10 subunit of a heme lyase K02200 - - 0.00000000000002643 75.0
HKD2_k127_107928_11 Heavy-metal resistance - - - 0.000000000004938 72.0
HKD2_k127_107928_12 - - - - 0.00000000007246 70.0
HKD2_k127_107928_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 539.0
HKD2_k127_107928_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 505.0
HKD2_k127_107928_4 Transcriptional regulator K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 404.0
HKD2_k127_107928_5 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 352.0
HKD2_k127_107928_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
HKD2_k127_107928_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
HKD2_k127_107928_9 Histidine kinase K07716 - 2.7.13.3 0.000000000000000000000000000000000000000007978 169.0
HKD2_k127_1095424_0 Glycosyl hydrolases family 15 - - - 6.231e-282 877.0
HKD2_k127_1095424_1 N-terminal domain of (some) glycogen debranching enzymes - - - 1.911e-256 810.0
HKD2_k127_1095424_2 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 596.0
HKD2_k127_1095424_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000852 249.0
HKD2_k127_1095424_4 secretion protein K02022,K12540 - - 0.0002916 46.0
HKD2_k127_114931_0 glutamine synthetase K01915 - 6.3.1.2 7.31e-269 831.0
HKD2_k127_114931_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 618.0
HKD2_k127_114931_11 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000009927 125.0
HKD2_k127_114931_12 Thioesterase superfamily - - - 0.000000000000000000000000000001221 128.0
HKD2_k127_114931_13 Protein of unknown function (DUF3175) - - - 0.000000000000000002525 96.0
HKD2_k127_114931_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 584.0
HKD2_k127_114931_3 Protein of unknown function (DUF1134) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 362.0
HKD2_k127_114931_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 355.0
HKD2_k127_114931_5 Domain of unknown function (4846) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 331.0
HKD2_k127_114931_6 Cadherin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
HKD2_k127_114931_7 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000971 207.0
HKD2_k127_114931_8 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000007012 169.0
HKD2_k127_114931_9 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000001222 163.0
HKD2_k127_1275303_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 533.0
HKD2_k127_1275303_1 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009811 254.0
HKD2_k127_1279873_0 Ligand-gated ion channel K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 434.0
HKD2_k127_1279873_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 257.0
HKD2_k127_1279873_2 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000007756 234.0
HKD2_k127_1279873_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000000000000000005321 196.0
HKD2_k127_1279873_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000002689 98.0
HKD2_k127_1293104_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.799e-245 772.0
HKD2_k127_1293104_1 Belongs to the peptidase M16 family K07263 - - 5.098e-208 655.0
HKD2_k127_1293104_10 Thioredoxin-like - - - 0.000000000000000000000000000000001018 136.0
HKD2_k127_1293104_11 Protein of unknown function (DUF1150) - - - 0.000000000000000000000000000002643 121.0
HKD2_k127_1293104_2 Peptidase M16 inactive domain K07263,K07623 - - 4.715e-196 620.0
HKD2_k127_1293104_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 433.0
HKD2_k127_1293104_4 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 349.0
HKD2_k127_1293104_5 Oxidoreductase molybdopterin binding K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 337.0
HKD2_k127_1293104_6 PFAM cytochrome c biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 311.0
HKD2_k127_1293104_7 methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002752 249.0
HKD2_k127_1293104_8 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000000000000246 226.0
HKD2_k127_1293104_9 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
HKD2_k127_1297677_0 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 5.058e-282 890.0
HKD2_k127_1297677_1 - - - - 1.013e-196 630.0
HKD2_k127_1297677_2 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 502.0
HKD2_k127_1297677_3 Alpha beta hydrolase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 383.0
HKD2_k127_1297677_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
HKD2_k127_1297677_5 Lipid A Biosynthesis N-terminal domain - - - 0.000000000000000000000000000000000000002716 149.0
HKD2_k127_1297677_6 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000009541 118.0
HKD2_k127_1297677_8 - - - - 0.0000005596 56.0
HKD2_k127_1297677_9 Bacteriophage replication gene A protein (GPA) - - - 0.0000006857 53.0
HKD2_k127_130094_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 425.0
HKD2_k127_130094_1 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 425.0
HKD2_k127_1307524_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.73e-316 971.0
HKD2_k127_1307524_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000005593 162.0
HKD2_k127_1307524_2 Peptidase M15 K02395 - - 0.000000000000000000000000000000006695 138.0
HKD2_k127_1307524_3 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000001618 134.0
HKD2_k127_1307524_4 BA14K-like protein - - - 0.0000000000000002526 86.0
HKD2_k127_1308306_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1224.0
HKD2_k127_1308306_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1189.0
HKD2_k127_1308306_10 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
HKD2_k127_1308306_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000004231 196.0
HKD2_k127_1308306_12 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000004651 197.0
HKD2_k127_1308306_13 Pentapeptide repeat protein K15352 - - 0.000000000000000000000000000000000000000000007768 178.0
HKD2_k127_1308306_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002327 150.0
HKD2_k127_1308306_2 Participates in both transcription termination and antitermination K02600 - - 5.663e-278 862.0
HKD2_k127_1308306_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 443.0
HKD2_k127_1308306_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 359.0
HKD2_k127_1308306_5 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 348.0
HKD2_k127_1308306_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 310.0
HKD2_k127_1308306_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
HKD2_k127_1308306_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 275.0
HKD2_k127_1308306_9 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002374 230.0
HKD2_k127_1320412_0 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 422.0
HKD2_k127_1320412_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 393.0
HKD2_k127_1320412_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000008303 253.0
HKD2_k127_1320412_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001624 87.0
HKD2_k127_1325517_0 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 437.0
HKD2_k127_1352409_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1385.0
HKD2_k127_1352409_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.154e-257 795.0
HKD2_k127_1352409_10 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000007872 243.0
HKD2_k127_1352409_11 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000001091 197.0
HKD2_k127_1352409_12 Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone K03880 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000334 182.0
HKD2_k127_1352409_13 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001511 161.0
HKD2_k127_1352409_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000002097 151.0
HKD2_k127_1352409_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000002577 97.0
HKD2_k127_1352409_19 Domain of unknown function (DUF1993) K09983 - - 0.0002916 46.0
HKD2_k127_1352409_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 3.571e-236 734.0
HKD2_k127_1352409_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 562.0
HKD2_k127_1352409_4 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 515.0
HKD2_k127_1352409_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006111 462.0
HKD2_k127_1352409_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 390.0
HKD2_k127_1352409_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 372.0
HKD2_k127_1352409_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 347.0
HKD2_k127_1352409_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
HKD2_k127_1362594_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1401.0
HKD2_k127_1362594_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 5.547e-238 746.0
HKD2_k127_1362594_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000007872 243.0
HKD2_k127_1362594_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.0000000000000000000003197 97.0
HKD2_k127_1381455_0 nuclear chromosome segregation - - - 1.497e-279 889.0
HKD2_k127_1381455_1 VWA domain containing CoxE-like protein K09989 - - 9.659e-206 646.0
HKD2_k127_1381455_2 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 543.0
HKD2_k127_1381455_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 407.0
HKD2_k127_1381455_4 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 354.0
HKD2_k127_1381455_5 ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000001607 182.0
HKD2_k127_1381455_7 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000002108 118.0
HKD2_k127_1381455_8 Histidine Phosphotransfer domain - - - 0.000000000000000000000001446 110.0
HKD2_k127_1402791_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1729.0
HKD2_k127_1402791_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 3.492e-302 933.0
HKD2_k127_1402791_10 Peptidase S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 396.0
HKD2_k127_1402791_11 Phage SPO1 DNA K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 349.0
HKD2_k127_1402791_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
HKD2_k127_1402791_13 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000008119 265.0
HKD2_k127_1402791_14 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000001798 261.0
HKD2_k127_1402791_15 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000001683 253.0
HKD2_k127_1402791_16 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD2_k127_1402791_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 243.0
HKD2_k127_1402791_18 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000001721 231.0
HKD2_k127_1402791_19 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000001543 179.0
HKD2_k127_1402791_2 Tetratricopeptide repeat - - - 5.245e-218 692.0
HKD2_k127_1402791_21 Putative prokaryotic signal transducing protein - - - 0.000000000005501 69.0
HKD2_k127_1402791_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 561.0
HKD2_k127_1402791_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 546.0
HKD2_k127_1402791_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 537.0
HKD2_k127_1402791_6 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 530.0
HKD2_k127_1402791_8 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 438.0
HKD2_k127_1402791_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 441.0
HKD2_k127_1417679_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 3.328e-214 678.0
HKD2_k127_1417679_3 Nucleoside triphosphate pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000002204 145.0
HKD2_k127_1417679_4 permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000001136 135.0
HKD2_k127_1417679_5 - - - - 0.0000000000000000000000000001921 123.0
HKD2_k127_14404_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 334.0
HKD2_k127_14404_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 304.0
HKD2_k127_14404_2 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001472 278.0
HKD2_k127_14404_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000001387 198.0
HKD2_k127_14404_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000001774 186.0
HKD2_k127_1465454_0 Peptidase family M3 K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 1.492e-286 895.0
HKD2_k127_1465454_1 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 441.0
HKD2_k127_1465454_2 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 310.0
HKD2_k127_1465454_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 293.0
HKD2_k127_1465454_4 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007686 270.0
HKD2_k127_1465454_5 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000000205 174.0
HKD2_k127_1482832_0 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 417.0
HKD2_k127_1482832_1 import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 275.0
HKD2_k127_1482832_2 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000001784 95.0
HKD2_k127_1482832_3 Smr domain - - - 0.000000000000007223 80.0
HKD2_k127_1498139_0 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 592.0
HKD2_k127_1498139_1 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000001686 99.0
HKD2_k127_1498139_2 Haem-degrading - - - 0.00000000000000000006381 91.0
HKD2_k127_1498139_3 - - - - 0.00000000007549 70.0
HKD2_k127_1501659_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.822e-231 719.0
HKD2_k127_1501659_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 449.0
HKD2_k127_1501659_2 - - - - 0.0000000000000000000000000000000004921 136.0
HKD2_k127_1524281_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 346.0
HKD2_k127_1524281_1 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 331.0
HKD2_k127_1524281_2 tetR family - - - 0.0000000000000000000000000000000000000000000000000000004136 199.0
HKD2_k127_1524281_3 - - - - 0.000000000000002106 76.0
HKD2_k127_1524281_4 TadE-like protein - - - 0.0007204 44.0
HKD2_k127_1648835_0 Elongation factor G, domain IV K02355 - - 4.347e-320 994.0
HKD2_k127_1648835_1 Aminotransferase K00812 - 2.6.1.1 1.168e-216 677.0
HKD2_k127_1648835_10 Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006496 258.0
HKD2_k127_1648835_11 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000102 237.0
HKD2_k127_1648835_12 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
HKD2_k127_1648835_13 peptidoglycan binding K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000008599 238.0
HKD2_k127_1648835_14 4-oxalocrotonate tautomerase - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
HKD2_k127_1648835_15 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000000008416 182.0
HKD2_k127_1648835_16 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000006515 175.0
HKD2_k127_1648835_17 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001597 175.0
HKD2_k127_1648835_18 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000005544 166.0
HKD2_k127_1648835_19 MFS_1 like family - - - 0.00000000000000000000000001539 113.0
HKD2_k127_1648835_2 Retinal pigment epithelial membrane protein - - - 4.061e-199 631.0
HKD2_k127_1648835_22 - - - - 0.00000000000000001761 85.0
HKD2_k127_1648835_23 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000004551 72.0
HKD2_k127_1648835_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 595.0
HKD2_k127_1648835_4 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 595.0
HKD2_k127_1648835_5 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 399.0
HKD2_k127_1648835_6 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
HKD2_k127_1648835_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HKD2_k127_1648835_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 290.0
HKD2_k127_1648835_9 Molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
HKD2_k127_1667151_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 5.035e-200 665.0
HKD2_k127_1667151_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 389.0
HKD2_k127_1667151_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000001049 189.0
HKD2_k127_1667151_3 Gram-negative porin - - - 0.000000000000000000000000000000000000000000002743 167.0
HKD2_k127_1667151_4 - - - - 0.000000000000000004033 86.0
HKD2_k127_1667151_5 HWE histidine kinase - - - 0.0000000000000001417 84.0
HKD2_k127_1667151_6 - - - - 0.00000000007111 70.0
HKD2_k127_1669482_0 Alpha-2-Macroglobulin K06894 - - 0.0 2319.0
HKD2_k127_1669482_1 AAA-like domain - - - 0.0 1661.0
HKD2_k127_1669482_10 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 536.0
HKD2_k127_1669482_11 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 527.0
HKD2_k127_1669482_12 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 528.0
HKD2_k127_1669482_13 2-deoxycytidine 5-triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 518.0
HKD2_k127_1669482_14 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 509.0
HKD2_k127_1669482_15 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 507.0
HKD2_k127_1669482_16 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 462.0
HKD2_k127_1669482_17 depolymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 466.0
HKD2_k127_1669482_18 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 325.0
HKD2_k127_1669482_19 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 306.0
HKD2_k127_1669482_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365,K05366 - 2.4.1.129,3.4.16.4 0.0 1101.0
HKD2_k127_1669482_20 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 301.0
HKD2_k127_1669482_21 Lipid A oxidase K12980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008314 286.0
HKD2_k127_1669482_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004453 278.0
HKD2_k127_1669482_23 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HKD2_k127_1669482_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000933 244.0
HKD2_k127_1669482_25 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
HKD2_k127_1669482_26 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000005897 215.0
HKD2_k127_1669482_27 Protein of unknown function (DUF2796) - - - 0.000000000000000000000000000000000000000000000004314 188.0
HKD2_k127_1669482_28 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000005356 171.0
HKD2_k127_1669482_29 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000001012 160.0
HKD2_k127_1669482_3 penicillin-binding protein K05367 - 2.4.1.129 6.056e-292 915.0
HKD2_k127_1669482_30 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000002271 156.0
HKD2_k127_1669482_31 - - - - 0.000000000000000000000000000000000002697 140.0
HKD2_k127_1669482_32 Cytochrome c K08738 - - 0.000000000000000000000000000000004897 146.0
HKD2_k127_1669482_36 small periplasmic lipoprotein - - - 0.000000000001237 73.0
HKD2_k127_1669482_4 Domain of unknown function (DUF4175) - - - 2.663e-248 794.0
HKD2_k127_1669482_5 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 2.209e-231 726.0
HKD2_k127_1669482_6 - - - - 8.14e-222 718.0
HKD2_k127_1669482_7 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 4.091e-206 648.0
HKD2_k127_1669482_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 7.285e-205 644.0
HKD2_k127_1669482_9 acetylornithine K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 582.0
HKD2_k127_1706093_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1150.0
HKD2_k127_1706093_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 459.0
HKD2_k127_1706093_10 Redoxin domain protein K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
HKD2_k127_1706093_11 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
HKD2_k127_1706093_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000008833 231.0
HKD2_k127_1706093_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
HKD2_k127_1706093_14 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000000000000000005926 216.0
HKD2_k127_1706093_15 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000001885 185.0
HKD2_k127_1706093_16 Transcription elongation factor - - - 0.000000000000000000000000000000000000000000000002286 179.0
HKD2_k127_1706093_17 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000000004619 185.0
HKD2_k127_1706093_18 - - - - 0.000000000000000000000000000000000000001424 153.0
HKD2_k127_1706093_19 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000004057 130.0
HKD2_k127_1706093_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 413.0
HKD2_k127_1706093_20 Transglycosylase SLT domain K08309 - - 0.00000000000000000002344 98.0
HKD2_k127_1706093_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 385.0
HKD2_k127_1706093_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 379.0
HKD2_k127_1706093_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 375.0
HKD2_k127_1706093_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 342.0
HKD2_k127_1706093_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 317.0
HKD2_k127_1706093_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 310.0
HKD2_k127_1706093_9 Secreted protein K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 308.0
HKD2_k127_176777_0 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000002712 149.0
HKD2_k127_176777_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00003487 52.0
HKD2_k127_176777_2 signal peptide protein - - - 0.0001221 50.0
HKD2_k127_17793_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.576e-310 955.0
HKD2_k127_17793_11 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000003778 164.0
HKD2_k127_17793_12 - - - - 0.00000000000000000000000000000006184 129.0
HKD2_k127_17793_13 peptidoglycan binding K03642 - - 0.0000000000000000000000000000001128 141.0
HKD2_k127_17793_14 AAA domain - - - 0.0000000000000000000000000000006098 124.0
HKD2_k127_17793_16 AAA domain - - - 0.00000000000000000002348 95.0
HKD2_k127_17793_17 - - - - 0.000000000007807 69.0
HKD2_k127_17793_18 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000004786 72.0
HKD2_k127_17793_2 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 314.0
HKD2_k127_17793_3 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 300.0
HKD2_k127_17793_4 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 253.0
HKD2_k127_17793_5 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 265.0
HKD2_k127_17793_6 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000694 228.0
HKD2_k127_17793_7 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000007189 216.0
HKD2_k127_17793_8 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000008127 201.0
HKD2_k127_17793_9 - - - - 0.0000000000000000000000000000000000000000002812 162.0
HKD2_k127_1818064_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 8.441e-273 844.0
HKD2_k127_1818064_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000006955 193.0
HKD2_k127_1818064_2 Polymer-forming cytoskeletal - - - 0.000000000000000000000000002513 116.0
HKD2_k127_1818064_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000004521 100.0
HKD2_k127_1861633_0 Nitrite and sulphite reductase 4Fe-4S domain K00381,K00392 - 1.8.1.2,1.8.7.1 1.268e-289 903.0
HKD2_k127_1861633_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 1.397e-288 895.0
HKD2_k127_1861633_10 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 463.0
HKD2_k127_1861633_11 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 450.0
HKD2_k127_1861633_12 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 440.0
HKD2_k127_1861633_13 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 427.0
HKD2_k127_1861633_14 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 385.0
HKD2_k127_1861633_15 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 381.0
HKD2_k127_1861633_16 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 391.0
HKD2_k127_1861633_17 TIGRFAM beta-ribofuranosylaminobenzene 5'-phosphate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 382.0
HKD2_k127_1861633_18 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 368.0
HKD2_k127_1861633_19 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 351.0
HKD2_k127_1861633_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 3.727e-204 649.0
HKD2_k127_1861633_20 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 360.0
HKD2_k127_1861633_21 Cold-shock K03704 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 339.0
HKD2_k127_1861633_22 PFAM Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 331.0
HKD2_k127_1861633_23 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 333.0
HKD2_k127_1861633_24 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 329.0
HKD2_k127_1861633_25 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 311.0
HKD2_k127_1861633_26 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 309.0
HKD2_k127_1861633_27 TIGRFAM H4MPT-linked C1 transfer pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
HKD2_k127_1861633_28 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 284.0
HKD2_k127_1861633_29 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 276.0
HKD2_k127_1861633_3 biosynthesis protein E K06139 - - 6.844e-204 642.0
HKD2_k127_1861633_30 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000009733 243.0
HKD2_k127_1861633_31 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
HKD2_k127_1861633_32 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000005798 226.0
HKD2_k127_1861633_33 Pfam:DUF556 - - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
HKD2_k127_1861633_34 PFAM aspartate glutamate uridylate kinase - - - 0.00000000000000000000000000000000000000000000000000000007308 207.0
HKD2_k127_1861633_35 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000000000000000000001373 180.0
HKD2_k127_1861633_36 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000000000000002709 184.0
HKD2_k127_1861633_37 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000542 168.0
HKD2_k127_1861633_38 - - - - 0.0000000000000000000000000000000000000000015 165.0
HKD2_k127_1861633_39 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.0000000000000000000000000000000000000005875 161.0
HKD2_k127_1861633_4 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 578.0
HKD2_k127_1861633_40 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000001443 152.0
HKD2_k127_1861633_41 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.000000000000000000000000000000000002746 142.0
HKD2_k127_1861633_42 Protein of unknown function (DUF2380) - - - 0.000000000000000000000000000000002932 135.0
HKD2_k127_1861633_43 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000002637 117.0
HKD2_k127_1861633_44 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000002143 115.0
HKD2_k127_1861633_46 - - - - 0.000008278 48.0
HKD2_k127_1861633_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 555.0
HKD2_k127_1861633_6 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 524.0
HKD2_k127_1861633_7 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 515.0
HKD2_k127_1861633_8 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 509.0
HKD2_k127_1861633_9 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 488.0
HKD2_k127_1871371_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 432.0
HKD2_k127_1871371_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004744 263.0
HKD2_k127_1871371_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000001127 179.0
HKD2_k127_1871371_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000002949 107.0
HKD2_k127_1871371_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000004408 51.0
HKD2_k127_189152_0 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 558.0
HKD2_k127_189152_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000526 192.0
HKD2_k127_189152_2 Cold shock protein domain K03704 - - 0.000000000000000000000000001783 117.0
HKD2_k127_189152_4 Methyltransferase domain - - - 0.0000002753 52.0
HKD2_k127_1896145_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 446.0
HKD2_k127_1896145_1 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 437.0
HKD2_k127_1896145_2 ABC-type transport auxiliary lipoprotein component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
HKD2_k127_1896145_3 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
HKD2_k127_1896145_4 Transcriptional regulator, Crp Fnr family K01420,K15861 - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD2_k127_1896145_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000007933 174.0
HKD2_k127_1896145_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000007271 156.0
HKD2_k127_1896145_7 - - - - 0.0000000191 60.0
HKD2_k127_1905941_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0 1017.0
HKD2_k127_1905941_1 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 356.0
HKD2_k127_1905941_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 282.0
HKD2_k127_191907_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 615.0
HKD2_k127_191907_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 533.0
HKD2_k127_191907_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 362.0
HKD2_k127_191907_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000001234 259.0
HKD2_k127_191907_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002481 254.0
HKD2_k127_191907_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000000007252 192.0
HKD2_k127_191907_6 protein dimerization activity K03746 - - 0.0000000000000000000000000000000000000003821 151.0
HKD2_k127_191907_7 Cytochrome c - - - 0.0000000000000000000000000001643 118.0
HKD2_k127_1954648_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788,K07789 - - 0.0 1292.0
HKD2_k127_1954648_1 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 445.0
HKD2_k127_1954648_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 306.0
HKD2_k127_1954648_3 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005725 273.0
HKD2_k127_1954648_4 - - - - 0.00000000000000000000001334 100.0
HKD2_k127_1956042_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 0.0 1416.0
HKD2_k127_1956042_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 8.916e-315 972.0
HKD2_k127_1956042_10 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 487.0
HKD2_k127_1956042_11 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 468.0
HKD2_k127_1956042_12 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 459.0
HKD2_k127_1956042_13 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 416.0
HKD2_k127_1956042_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 387.0
HKD2_k127_1956042_15 Proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
HKD2_k127_1956042_16 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
HKD2_k127_1956042_17 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 363.0
HKD2_k127_1956042_18 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 350.0
HKD2_k127_1956042_19 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 330.0
HKD2_k127_1956042_2 Circularly permuted ATP-grasp type 2 - - - 7.888e-247 767.0
HKD2_k127_1956042_20 Protein of unknown function (DUF2793) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 303.0
HKD2_k127_1956042_21 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
HKD2_k127_1956042_22 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000001443 230.0
HKD2_k127_1956042_23 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000001015 204.0
HKD2_k127_1956042_24 Protein of unknown function (DUF2793) - - - 0.00000000000000000000000000000000000000000000005889 181.0
HKD2_k127_1956042_26 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000898 106.0
HKD2_k127_1956042_28 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000009413 91.0
HKD2_k127_1956042_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.115e-229 721.0
HKD2_k127_1956042_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.461e-227 709.0
HKD2_k127_1956042_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 7.316e-207 653.0
HKD2_k127_1956042_6 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.238e-204 643.0
HKD2_k127_1956042_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 587.0
HKD2_k127_1956042_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 554.0
HKD2_k127_1956042_9 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 527.0
HKD2_k127_20557_0 Diguanylate cyclase phosphodiesterase with PAS PAC K13245 - 3.1.4.52 0.0 1440.0
HKD2_k127_20557_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1254.0
HKD2_k127_20557_10 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
HKD2_k127_20557_11 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 301.0
HKD2_k127_20557_12 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 299.0
HKD2_k127_20557_13 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
HKD2_k127_20557_14 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001348 259.0
HKD2_k127_20557_15 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000008257 248.0
HKD2_k127_20557_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009883 248.0
HKD2_k127_20557_17 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
HKD2_k127_20557_18 chitinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000792 258.0
HKD2_k127_20557_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000001963 198.0
HKD2_k127_20557_2 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 4.281e-196 621.0
HKD2_k127_20557_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000004233 196.0
HKD2_k127_20557_21 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000000000001669 156.0
HKD2_k127_20557_22 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000000000000000000001341 143.0
HKD2_k127_20557_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000002036 132.0
HKD2_k127_20557_24 - - - - 0.00000000000000000000002794 114.0
HKD2_k127_20557_25 SURF1-like protein K14998 - - 0.0000000000000000002499 89.0
HKD2_k127_20557_26 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000004338 87.0
HKD2_k127_20557_3 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 5.044e-194 610.0
HKD2_k127_20557_4 flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 556.0
HKD2_k127_20557_5 endonuclease III K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 544.0
HKD2_k127_20557_6 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 526.0
HKD2_k127_20557_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 482.0
HKD2_k127_20557_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 456.0
HKD2_k127_20557_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 361.0
HKD2_k127_2095756_0 oligoendopeptidase K08602 - - 4.455e-301 933.0
HKD2_k127_2095756_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.624e-298 925.0
HKD2_k127_2095756_10 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
HKD2_k127_2095756_11 Protein of unknown function (DUF1036) - - - 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
HKD2_k127_2095756_12 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000007971 179.0
HKD2_k127_2095756_13 Belongs to the UPF0335 family - - - 0.000000000000000000000000000000009957 130.0
HKD2_k127_2095756_15 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000003401 75.0
HKD2_k127_2095756_16 Protein of unknown function (DUF2892) - - - 0.00000000000001401 76.0
HKD2_k127_2095756_17 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000001477 76.0
HKD2_k127_2095756_18 membrane protein (DUF2078) K08982 - - 0.00000000004101 66.0
HKD2_k127_2095756_2 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 8.849e-256 797.0
HKD2_k127_2095756_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.682e-233 729.0
HKD2_k127_2095756_4 ErfK YbiS YcfS YnhG family protein K21470 - - 5.75e-206 657.0
HKD2_k127_2095756_5 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 608.0
HKD2_k127_2095756_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 571.0
HKD2_k127_2095756_7 LysR substrate binding domain K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 456.0
HKD2_k127_2095756_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 407.0
HKD2_k127_2095756_9 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 401.0
HKD2_k127_2128591_0 Transglycosylase SLT domain K08309 - - 2.02e-243 767.0
HKD2_k127_2128591_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 381.0
HKD2_k127_2128591_10 BON domain - - - 0.0000000000000000000000000000000000000000000000000007237 190.0
HKD2_k127_2128591_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000004611 130.0
HKD2_k127_2128591_12 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000001185 123.0
HKD2_k127_2128591_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001728 106.0
HKD2_k127_2128591_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.00006773 51.0
HKD2_k127_2128591_2 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 317.0
HKD2_k127_2128591_3 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005301 249.0
HKD2_k127_2128591_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000001816 241.0
HKD2_k127_2128591_5 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
HKD2_k127_2128591_6 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000005457 230.0
HKD2_k127_2128591_7 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000000000000000085 208.0
HKD2_k127_2128591_8 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
HKD2_k127_2128591_9 Haemolysin-III related K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000007549 200.0
HKD2_k127_214912_0 Sulfide dehydrogenase K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 513.0
HKD2_k127_214912_1 - - - - 0.00000000000000000000000000000000000000000000000000000001878 207.0
HKD2_k127_214912_2 oxidation protein (SoxZ) K17227 - - 0.00000000000000000000000000000000004953 140.0
HKD2_k127_214912_3 sulfur oxidation protein (SoxY) K17226 - - 0.000000000000000000000000000001638 126.0
HKD2_k127_214912_4 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000002201 94.0
HKD2_k127_2293076_0 Proton-conducting membrane transporter K12141 - - 2.278e-244 761.0
HKD2_k127_2293076_1 NADH-ubiquinone oxidoreductase chain 49kDa - - - 5.808e-224 704.0
HKD2_k127_2293076_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 487.0
HKD2_k127_2293076_3 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 332.0
HKD2_k127_2293076_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001874 279.0
HKD2_k127_2293076_5 Proton-conducting membrane transporter - - - 0.00000000000000000000000000000000000000000000004701 171.0
HKD2_k127_239205_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 591.0
HKD2_k127_239205_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 558.0
HKD2_k127_239205_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 516.0
HKD2_k127_239205_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000001459 99.0
HKD2_k127_2567092_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.759e-307 955.0
HKD2_k127_2567092_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 533.0
HKD2_k127_2567092_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000955 61.0
HKD2_k127_2567092_2 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 403.0
HKD2_k127_2567092_3 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 394.0
HKD2_k127_2567092_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 328.0
HKD2_k127_2567092_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002439 271.0
HKD2_k127_2567092_7 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000003256 213.0
HKD2_k127_2567092_8 molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000004708 171.0
HKD2_k127_2567092_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000335 150.0
HKD2_k127_2585170_0 E1 component K00164 - 1.2.4.2 0.0 1309.0
HKD2_k127_2585170_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5,6.2.1.9 4.451e-195 614.0
HKD2_k127_2585170_10 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 266.0
HKD2_k127_2585170_11 Zinc-dependent metalloprotease - - - 0.00000000000000000000000000000000000000000000000000000000000000008534 232.0
HKD2_k127_2585170_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001495 211.0
HKD2_k127_2585170_13 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000003446 136.0
HKD2_k127_2585170_14 - - - - 0.000000000000000000001174 100.0
HKD2_k127_2585170_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 574.0
HKD2_k127_2585170_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 498.0
HKD2_k127_2585170_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 499.0
HKD2_k127_2585170_5 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 458.0
HKD2_k127_2585170_6 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 401.0
HKD2_k127_2585170_7 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 305.0
HKD2_k127_2585170_9 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001338 264.0
HKD2_k127_2591961_0 Glycosyl transferase family group 2 K22278 - 3.5.1.104 0.0 1197.0
HKD2_k127_2591961_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 356.0
HKD2_k127_2591961_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 290.0
HKD2_k127_2591961_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000002758 235.0
HKD2_k127_2591961_4 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.00000000000000000000000000000000001019 146.0
HKD2_k127_2591961_5 Peptidase propeptide and YPEB domain - - - 0.000000000000000000000003887 106.0
HKD2_k127_2591961_6 Sarcosine oxidase, alpha subunit family K00302 - 1.5.3.1 0.000000000000000000007243 93.0
HKD2_k127_2608728_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003413 269.0
HKD2_k127_2608728_1 integral membrane protein - - - 0.00000000000000000000000000000000000000000000001843 177.0
HKD2_k127_2608728_2 - - - - 0.00000000000000000003111 100.0
HKD2_k127_2608728_3 - - - - 0.00000000000000000009107 100.0
HKD2_k127_2612508_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 7.18e-277 861.0
HKD2_k127_2612508_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 1.187e-225 708.0
HKD2_k127_2612508_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 622.0
HKD2_k127_2612508_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 460.0
HKD2_k127_2612508_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 341.0
HKD2_k127_2612508_5 KR domain K00038 - 1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 332.0
HKD2_k127_2612508_7 - - - - 0.0000000003921 63.0
HKD2_k127_2615865_0 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 576.0
HKD2_k127_2615865_1 Binding-protein-dependent transport system inner membrane component K09971 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 516.0
HKD2_k127_2615865_10 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000000002467 185.0
HKD2_k127_2615865_11 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000001858 161.0
HKD2_k127_2615865_12 ATPase involved in DNA repair - - - 0.0000000000000000000000000000003796 134.0
HKD2_k127_2615865_2 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
HKD2_k127_2615865_3 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 460.0
HKD2_k127_2615865_4 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 432.0
HKD2_k127_2615865_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 430.0
HKD2_k127_2615865_6 ABC transporter K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 372.0
HKD2_k127_2615865_7 DNA repair exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 263.0
HKD2_k127_2615865_8 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000003134 233.0
HKD2_k127_2615865_9 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000008196 190.0
HKD2_k127_2635654_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 3.35e-223 698.0
HKD2_k127_2635654_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 346.0
HKD2_k127_2638862_0 Domain of unknown function (DUF1974) K06445 - - 0.0 1230.0
HKD2_k127_2638862_1 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 6.613e-305 947.0
HKD2_k127_2638862_10 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
HKD2_k127_2638862_11 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.0000000000000000000000000000000000000000000000000000000000000069 224.0
HKD2_k127_2638862_12 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000004774 223.0
HKD2_k127_2638862_13 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000002045 212.0
HKD2_k127_2638862_14 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000006241 188.0
HKD2_k127_2638862_15 Phosphopantetheine attachment site K02078,K14661 - - 0.0000000000000000000000000000000000000006862 150.0
HKD2_k127_2638862_17 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000005524 160.0
HKD2_k127_2638862_18 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000002037 147.0
HKD2_k127_2638862_19 protein conserved in bacteria K07401 - - 0.0000000000000000000000000001942 115.0
HKD2_k127_2638862_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.131e-252 790.0
HKD2_k127_2638862_20 Protein of unknown function (DUF559) - - - 0.00000000000000000000000003857 111.0
HKD2_k127_2638862_22 Protein of unknown function (DUF1236) - - - 0.0000000000000000002911 102.0
HKD2_k127_2638862_3 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 7.98e-220 686.0
HKD2_k127_2638862_4 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 5.088e-210 659.0
HKD2_k127_2638862_5 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 4.276e-203 640.0
HKD2_k127_2638862_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 413.0
HKD2_k127_2638862_7 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 411.0
HKD2_k127_2638862_8 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 354.0
HKD2_k127_2638862_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 323.0
HKD2_k127_2645745_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.216e-206 652.0
HKD2_k127_2645745_1 PQQ-like domain K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 565.0
HKD2_k127_2645745_10 Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 330.0
HKD2_k127_2645745_11 Protein of unknown function (DUF1134) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 301.0
HKD2_k127_2645745_12 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 284.0
HKD2_k127_2645745_13 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001294 267.0
HKD2_k127_2645745_14 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003314 275.0
HKD2_k127_2645745_15 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009078 253.0
HKD2_k127_2645745_16 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003187 247.0
HKD2_k127_2645745_17 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001908 237.0
HKD2_k127_2645745_18 DNA polymerase III chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
HKD2_k127_2645745_19 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000005266 216.0
HKD2_k127_2645745_2 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 494.0
HKD2_k127_2645745_20 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000005842 221.0
HKD2_k127_2645745_21 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000001125 167.0
HKD2_k127_2645745_22 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000005089 155.0
HKD2_k127_2645745_23 - - - - 0.000000000000000000000000000000000000001148 157.0
HKD2_k127_2645745_24 MOSC domain - - - 0.0000000000000000000000000000000000007913 153.0
HKD2_k127_2645745_25 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000000000003598 136.0
HKD2_k127_2645745_26 Cold shock K03704 - - 0.00000000000000000000000000000000005717 134.0
HKD2_k127_2645745_28 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000001443 126.0
HKD2_k127_2645745_29 Cupredoxin-like domain - - - 0.0000000000000000000000000002657 119.0
HKD2_k127_2645745_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 452.0
HKD2_k127_2645745_30 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.0000000000001158 74.0
HKD2_k127_2645745_34 regulation of RNA biosynthetic process - - - 0.00003745 46.0
HKD2_k127_2645745_4 PRMT5 oligomerisation domain K11434 - 2.1.1.319 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 421.0
HKD2_k127_2645745_5 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 422.0
HKD2_k127_2645745_6 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 411.0
HKD2_k127_2645745_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 384.0
HKD2_k127_2645745_8 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 327.0
HKD2_k127_2645745_9 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 329.0
HKD2_k127_2650825_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 581.0
HKD2_k127_2650825_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 392.0
HKD2_k127_2650825_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 248.0
HKD2_k127_2650825_3 Belongs to the HesB IscA family K13628,K15724 - - 0.00000000000000124 76.0
HKD2_k127_2676234_0 Zinc-binding dehydrogenase K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 450.0
HKD2_k127_2676234_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000009289 152.0
HKD2_k127_2676234_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000003189 127.0
HKD2_k127_2688247_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 465.0
HKD2_k127_2688247_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 457.0
HKD2_k127_2688247_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 400.0
HKD2_k127_2688247_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 331.0
HKD2_k127_2688247_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000009966 213.0
HKD2_k127_2688247_5 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000006151 196.0
HKD2_k127_2688247_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000003165 117.0
HKD2_k127_2688247_7 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000004178 81.0
HKD2_k127_2709861_0 Lipase maturation factor - - - 4.821e-245 769.0
HKD2_k127_2709861_1 penicillin-binding protein K03587 - 3.4.16.4 1.261e-195 626.0
HKD2_k127_2709861_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 454.0
HKD2_k127_2709861_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 411.0
HKD2_k127_2709861_4 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003983 267.0
HKD2_k127_2709861_5 Dihydrofolate reductase K17364 - 1.5.1.47 0.000000000000000000000000000000000000000000000000000000000002007 211.0
HKD2_k127_2709861_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000008201 149.0
HKD2_k127_2709861_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000005109 121.0
HKD2_k127_2709861_8 - - - - 0.0000000000000000000001476 102.0
HKD2_k127_2709861_9 - - - - 0.0000000000000000004672 91.0
HKD2_k127_2711626_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1273.0
HKD2_k127_2711626_1 Amidohydrolase family K01465 - 3.5.2.3 3.256e-232 730.0
HKD2_k127_2711626_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 344.0
HKD2_k127_2711626_11 Lysine exporter protein LysE YggA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 308.0
HKD2_k127_2711626_12 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 313.0
HKD2_k127_2711626_13 glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007479 279.0
HKD2_k127_2711626_14 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 265.0
HKD2_k127_2711626_15 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
HKD2_k127_2711626_16 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000001692 228.0
HKD2_k127_2711626_17 - - - - 0.00000000000000000000000000000000000000000000000000001872 198.0
HKD2_k127_2711626_18 Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues - - - 0.00000000000000000000000000000000000000000000000000002214 209.0
HKD2_k127_2711626_19 Protein of unknown function (DUF2385) - - - 0.0000000000000000000000000000000000000000000002192 170.0
HKD2_k127_2711626_2 Peptidase dimerisation domain K01436 - - 9.325e-223 698.0
HKD2_k127_2711626_20 Cupin - - - 0.000000000000000000000000000000000000001045 151.0
HKD2_k127_2711626_21 - - - - 0.0000000000000000000000005865 107.0
HKD2_k127_2711626_23 Short-chain dehydrogenase reductase SDR K13775 - - 0.0000000000000000000003186 96.0
HKD2_k127_2711626_24 Domain of unknown function (DUF1902) - - - 0.00004968 51.0
HKD2_k127_2711626_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.152e-200 641.0
HKD2_k127_2711626_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 553.0
HKD2_k127_2711626_5 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 555.0
HKD2_k127_2711626_6 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 530.0
HKD2_k127_2711626_7 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 481.0
HKD2_k127_2711626_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 477.0
HKD2_k127_2711626_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 383.0
HKD2_k127_272113_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 549.0
HKD2_k127_272113_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 456.0
HKD2_k127_272113_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 301.0
HKD2_k127_272113_11 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000001516 195.0
HKD2_k127_272113_12 Membrane fusogenic activity K09806 - - 0.00000000000000000000000008397 112.0
HKD2_k127_272113_13 serine threonine protein kinase - - - 0.00000000000000002135 95.0
HKD2_k127_272113_14 Bacterial regulatory proteins, tetR family - - - 0.0004424 45.0
HKD2_k127_272113_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
HKD2_k127_272113_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 402.0
HKD2_k127_272113_4 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 387.0
HKD2_k127_272113_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 329.0
HKD2_k127_272113_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 321.0
HKD2_k127_272113_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 308.0
HKD2_k127_272113_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 304.0
HKD2_k127_272113_9 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 304.0
HKD2_k127_2730307_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 424.0
HKD2_k127_2730307_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000005784 149.0
HKD2_k127_2730307_2 - - - - 0.000000000000000000008923 99.0
HKD2_k127_2730307_3 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000005194 60.0
HKD2_k127_2730621_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 467.0
HKD2_k127_2730621_1 receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 476.0
HKD2_k127_2730621_10 Molybdenum ABC transporter K02020 - - 0.00000000000000000000000000000000000000000000000000000000000008936 222.0
HKD2_k127_2730621_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000002156 200.0
HKD2_k127_2730621_12 MafB19-like deaminase - - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
HKD2_k127_2730621_13 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000000000006952 198.0
HKD2_k127_2730621_14 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000001505 182.0
HKD2_k127_2730621_15 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000004297 155.0
HKD2_k127_2730621_16 nuclear export factor GLE1 K09796 - - 0.0000000000000000000000000000000000002675 145.0
HKD2_k127_2730621_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 452.0
HKD2_k127_2730621_3 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 426.0
HKD2_k127_2730621_4 PFAM ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 360.0
HKD2_k127_2730621_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 362.0
HKD2_k127_2730621_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 328.0
HKD2_k127_2730621_7 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001821 253.0
HKD2_k127_2730621_8 ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000001042 246.0
HKD2_k127_2730621_9 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000005735 226.0
HKD2_k127_2742448_0 lytic murein transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 508.0
HKD2_k127_2742448_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 477.0
HKD2_k127_2742448_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 429.0
HKD2_k127_2742448_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
HKD2_k127_2742448_4 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 346.0
HKD2_k127_2742448_5 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
HKD2_k127_2742448_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
HKD2_k127_2742448_7 Membrane K03646 - - 0.0000000000000000000000000000000000000000000000008413 196.0
HKD2_k127_2742448_8 Protein of unknown function (DUF4236) - - - 0.000000000000000000000000000000000000000000007284 167.0
HKD2_k127_2742448_9 cytokinin biosynthetic process - - - 0.0000000000000000000000000000000000000000000164 167.0
HKD2_k127_2745115_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1474.0
HKD2_k127_2745115_1 low-complexity proteins - - - 7.457e-232 737.0
HKD2_k127_2745115_2 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 359.0
HKD2_k127_2745115_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
HKD2_k127_2745115_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000001507 200.0
HKD2_k127_2745115_5 OmpW family K07275 - - 0.000000000000000000000000000000000000000000004114 167.0
HKD2_k127_2745115_6 Crp-like helix-turn-helix domain K01420 - - 0.000000000000000000000000000000000000007301 158.0
HKD2_k127_2745115_7 PRC-barrel domain - - - 0.0000000000000000000000000000000000000302 154.0
HKD2_k127_2745115_8 Sodium:dicarboxylate symporter family K11103 - - 0.000000000000000000001151 94.0
HKD2_k127_2745115_9 COG3047 Outer membrane protein W K07275 - - 0.0000000000000004033 84.0
HKD2_k127_2773389_0 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 485.0
HKD2_k127_2773389_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 454.0
HKD2_k127_2773389_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 306.0
HKD2_k127_2773389_3 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000001088 241.0
HKD2_k127_2773389_4 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000000000000000002572 195.0
HKD2_k127_2773389_5 protein conserved in bacteria - - - 0.000000000000000000000000000000009527 130.0
HKD2_k127_2773389_6 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000003348 81.0
HKD2_k127_2789508_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1780.0
HKD2_k127_2789508_1 Helicase K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.0 1090.0
HKD2_k127_2789508_2 Extracellular solute-binding protein K02035,K13893 - - 7.511e-260 813.0
HKD2_k127_2789508_3 AMP-binding enzyme C-terminal domain - - - 2.187e-209 671.0
HKD2_k127_2789508_4 Invasion associated locus B (IalB) protein - - - 0.000000000000000000000000000000000000005636 154.0
HKD2_k127_2789508_5 - - - - 0.000000000000000000000000006107 117.0
HKD2_k127_2789508_6 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000009209 103.0
HKD2_k127_2798473_0 GMC oxidoreductase K03333 - 1.1.3.6 0.0 1072.0
HKD2_k127_2798473_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 1.056e-244 760.0
HKD2_k127_2798473_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 502.0
HKD2_k127_2798473_3 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 398.0
HKD2_k127_2798473_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 320.0
HKD2_k127_2798473_5 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 323.0
HKD2_k127_2798473_6 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000002035 164.0
HKD2_k127_2798473_7 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.0000000000000000000007656 96.0
HKD2_k127_2815174_0 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 430.0
HKD2_k127_2815174_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 400.0
HKD2_k127_2815174_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 390.0
HKD2_k127_2815174_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
HKD2_k127_2815174_4 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000000000002628 126.0
HKD2_k127_2815174_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000001935 118.0
HKD2_k127_2824541_0 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 6.282e-197 616.0
HKD2_k127_2824541_1 cobalt chelatase K09883 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 524.0
HKD2_k127_2824541_2 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 449.0
HKD2_k127_2824541_3 heat shock protein DnaJ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 293.0
HKD2_k127_2824541_4 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000000000000001617 137.0
HKD2_k127_2824839_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1431.0
HKD2_k127_2824839_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 7.966e-221 717.0
HKD2_k127_2824839_2 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 567.0
HKD2_k127_2824839_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 433.0
HKD2_k127_2824839_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 308.0
HKD2_k127_2824839_5 Lipopolysaccharide-assembly K03643 - - 0.000000000000000000000000346 110.0
HKD2_k127_2824839_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000004894 91.0
HKD2_k127_2906382_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0031317,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0071702,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 560.0
HKD2_k127_2906382_1 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
HKD2_k127_2906382_2 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000001075 169.0
HKD2_k127_2906382_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000001097 59.0
HKD2_k127_2913637_0 Cytochrome c-type biogenesis protein K02198 - - 0.0 1018.0
HKD2_k127_2913637_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 592.0
HKD2_k127_2913637_2 Two component transcriptional regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 413.0
HKD2_k127_2913637_3 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 317.0
HKD2_k127_2913637_4 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003378 228.0
HKD2_k127_2913637_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000003794 218.0
HKD2_k127_2913637_6 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000001779 156.0
HKD2_k127_2913637_7 Protein of unknown function (DUF1428) - - - 0.000000000000000000001069 97.0
HKD2_k127_2913637_8 - K01077 - 3.1.3.1 0.0000000002229 68.0
HKD2_k127_3063110_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1377.0
HKD2_k127_3063110_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 546.0
HKD2_k127_3063110_10 TPR repeat - - - 0.000000000000000004487 99.0
HKD2_k127_3063110_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 473.0
HKD2_k127_3063110_3 peptidyl-prolyl isomerase K01802,K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 293.0
HKD2_k127_3063110_4 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 258.0
HKD2_k127_3063110_5 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
HKD2_k127_3063110_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000002008 199.0
HKD2_k127_3063110_7 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000008104 177.0
HKD2_k127_3063110_8 transcriptional K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000001543 154.0
HKD2_k127_3063110_9 Putative cyclase - - - 0.00000000000000000000000006582 108.0
HKD2_k127_3066227_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.052e-222 701.0
HKD2_k127_3066227_1 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 245.0
HKD2_k127_3066227_2 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000002245 189.0
HKD2_k127_3066227_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000007402 167.0
HKD2_k127_3066227_4 Protein of unknown function (DUF1491) - - - 0.00000000000000000000000000000000000000009575 153.0
HKD2_k127_3066227_5 integral membrane protein - - - 0.00000000000000000000000000000000000002335 158.0
HKD2_k127_3066227_6 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000007538 137.0
HKD2_k127_3087140_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 536.0
HKD2_k127_3087140_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000002207 227.0
HKD2_k127_3087140_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000134 59.0
HKD2_k127_3087140_3 Domain of unknown function (DUF4212) - - - 0.0000004588 55.0
HKD2_k127_3098375_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 553.0
HKD2_k127_3098375_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 435.0
HKD2_k127_3098375_2 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 433.0
HKD2_k127_3098375_3 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 368.0
HKD2_k127_3098375_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
HKD2_k127_3098375_5 Preprotein translocase K03210 - - 0.0000000000000000000000000000000000000000007337 159.0
HKD2_k127_3098375_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000008897 140.0
HKD2_k127_3098375_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000001392 119.0
HKD2_k127_3098375_8 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.000000000000000000000000004932 119.0
HKD2_k127_3098375_9 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000006086 121.0
HKD2_k127_3105375_0 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 544.0
HKD2_k127_3105375_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 320.0
HKD2_k127_3105375_2 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007529 279.0
HKD2_k127_3105375_3 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000001045 151.0
HKD2_k127_317782_0 extracellular polysaccharide biosynthetic process K16554 - - 0.0 1053.0
HKD2_k127_317782_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.556e-208 654.0
HKD2_k127_317782_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006812 107.0
HKD2_k127_317782_11 - - - - 0.0000000008438 61.0
HKD2_k127_317782_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 468.0
HKD2_k127_317782_3 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 425.0
HKD2_k127_317782_4 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 387.0
HKD2_k127_317782_5 ABC 3 transport family K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 301.0
HKD2_k127_317782_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000005006 266.0
HKD2_k127_317782_7 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000000000008731 225.0
HKD2_k127_317782_8 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000000000000000000000000003064 200.0
HKD2_k127_317782_9 EF hand - - - 0.000000000000000000000000000000000000000000000000006023 187.0
HKD2_k127_3187479_0 Domain of unknown function (DUF4159) - - - 0.0 1209.0
HKD2_k127_3187479_1 membrane - - - 0.0 1051.0
HKD2_k127_3187479_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 599.0
HKD2_k127_3187479_3 ATPase AAA K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 564.0
HKD2_k127_3187479_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 437.0
HKD2_k127_3187479_5 protein conserved in bacteria K09986 - - 0.0000000000000000000000000000000000000000000000000000000181 201.0
HKD2_k127_3187479_6 - - - - 0.0000000000000000000000000007499 118.0
HKD2_k127_3222858_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.707e-254 793.0
HKD2_k127_3222858_1 Involved in the TonB-independent uptake of proteins K03641 - - 1.839e-227 712.0
HKD2_k127_3222858_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 314.0
HKD2_k127_3222858_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 303.0
HKD2_k127_3222858_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003183 241.0
HKD2_k127_3222858_5 TIGRFAM protein TolA K03646 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
HKD2_k127_3222858_6 chlorophyll binding K02067,K03286,K03640 - - 0.000000000000000000000000000000000003232 155.0
HKD2_k127_336050_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0 1144.0
HKD2_k127_336050_1 GntP family permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 395.0
HKD2_k127_336050_2 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 329.0
HKD2_k127_336050_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000006472 234.0
HKD2_k127_336050_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000002364 141.0
HKD2_k127_336050_5 Bacterial dnaA protein helix-turn-helix domain - - - 0.00000000000000000000000000000000003274 139.0
HKD2_k127_33631_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1124.0
HKD2_k127_33631_1 - - - - 8.696e-243 762.0
HKD2_k127_33631_10 GDYXXLXY protein - - - 0.00000000000000000000000000000000005276 152.0
HKD2_k127_33631_11 Ubiquinol-cytochrome C chaperone K17662 - - 0.0000000000000000000000000000000001866 139.0
HKD2_k127_33631_12 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.000000000000000000000000000005857 134.0
HKD2_k127_33631_14 Bacterial protein of unknown function (DUF937) - - - 0.0000001373 62.0
HKD2_k127_33631_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.548e-237 741.0
HKD2_k127_33631_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 559.0
HKD2_k127_33631_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 552.0
HKD2_k127_33631_5 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 355.0
HKD2_k127_33631_6 SmpA / OmlA family - - - 0.00000000000000000000000000000000000000000000000000000001129 203.0
HKD2_k127_33631_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000001427 181.0
HKD2_k127_33631_8 Uncharacterized ACR, COG1399 - - - 0.0000000000000000000000000000000000000000001214 167.0
HKD2_k127_33631_9 MerR family regulatory protein - - - 0.000000000000000000000000000000000000000000962 162.0
HKD2_k127_350167_0 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
HKD2_k127_350167_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002344 261.0
HKD2_k127_350167_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
HKD2_k127_350167_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001303 231.0
HKD2_k127_350167_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000008402 206.0
HKD2_k127_350167_5 - - - - 0.0000000000003522 74.0
HKD2_k127_3544675_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1015.0
HKD2_k127_3544675_1 B12 binding domain - - - 1.045e-213 676.0
HKD2_k127_3544675_2 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 1.027e-202 637.0
HKD2_k127_3544675_3 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
HKD2_k127_3544675_4 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000829 264.0
HKD2_k127_3544675_5 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000000000004541 120.0
HKD2_k127_355518_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1708.0
HKD2_k127_355518_1 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 0.0 1058.0
HKD2_k127_355518_10 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
HKD2_k127_355518_11 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 353.0
HKD2_k127_355518_12 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 348.0
HKD2_k127_355518_13 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 340.0
HKD2_k127_355518_14 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 308.0
HKD2_k127_355518_15 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
HKD2_k127_355518_16 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000005575 177.0
HKD2_k127_355518_17 - - - - 0.000000000000000000000000000000000000000000009763 172.0
HKD2_k127_355518_18 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000002151 158.0
HKD2_k127_355518_19 Universal stress protein - - - 0.00000000000000000000000000000000000000002233 164.0
HKD2_k127_355518_2 Circularly permuted ATP-grasp type 2 - - - 5e-324 1012.0
HKD2_k127_355518_20 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000001782 149.0
HKD2_k127_355518_21 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000001732 123.0
HKD2_k127_355518_22 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000001201 119.0
HKD2_k127_355518_23 - - - - 0.00000000000000000000000005355 109.0
HKD2_k127_355518_24 PQ loop repeat K15383 - - 0.000000000000000000000008057 103.0
HKD2_k127_355518_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000002139 93.0
HKD2_k127_355518_3 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 7.484e-302 949.0
HKD2_k127_355518_4 CoA binding domain K09181 - - 5.054e-255 799.0
HKD2_k127_355518_5 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 1.713e-239 756.0
HKD2_k127_355518_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 612.0
HKD2_k127_355518_7 Zeta toxin K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 513.0
HKD2_k127_355518_8 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
HKD2_k127_355518_9 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 426.0
HKD2_k127_358215_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.372e-278 856.0
HKD2_k127_358215_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 537.0
HKD2_k127_358215_10 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000008698 203.0
HKD2_k127_358215_12 amine dehydrogenase activity - - - 0.000000000000000000000000000003886 125.0
HKD2_k127_358215_13 GTP-binding protein TypA K06207 - - 0.000000000000002272 77.0
HKD2_k127_358215_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 456.0
HKD2_k127_358215_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 379.0
HKD2_k127_358215_4 Major facilitator Superfamily K03761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
HKD2_k127_358215_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000787 271.0
HKD2_k127_358215_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HKD2_k127_358215_7 Major facilitator Superfamily K03761 - - 0.000000000000000000000000000000000000000000000000000000000000000000002289 238.0
HKD2_k127_358215_8 Glyoxalase-like domain K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000003163 225.0
HKD2_k127_358215_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000002204 209.0
HKD2_k127_3662761_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
HKD2_k127_3662761_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 235.0
HKD2_k127_3662761_2 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000000005683 122.0
HKD2_k127_3662761_3 Bacterial signalling protein N terminal repeat - - - 0.00000000000000000000000000002413 131.0
HKD2_k127_3830277_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HKD2_k127_3830277_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 463.0
HKD2_k127_3830277_11 TonB-dependent receptor - - - 0.0003034 46.0
HKD2_k127_3830277_2 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
HKD2_k127_3830277_3 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 316.0
HKD2_k127_3830277_4 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000001745 230.0
HKD2_k127_3830277_5 - - - - 0.0000000000000000000000000000000000004515 145.0
HKD2_k127_3830277_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000007161 150.0
HKD2_k127_3830277_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000007396 97.0
HKD2_k127_3830277_8 - - - - 0.000000000000000000001535 102.0
HKD2_k127_3830277_9 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000001625 69.0
HKD2_k127_3831360_0 receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 494.0
HKD2_k127_3831360_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 292.0
HKD2_k127_3831360_2 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000005974 200.0
HKD2_k127_3831360_3 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000000000006733 196.0
HKD2_k127_3831360_4 - - - - 0.0000000000000000000000000000000000000000000004038 171.0
HKD2_k127_3831360_5 receptor K02014 - - 0.000000000000006208 87.0
HKD2_k127_3836269_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1186.0
HKD2_k127_3836269_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.242e-239 750.0
HKD2_k127_3836269_10 plasmid maintenance K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 419.0
HKD2_k127_3836269_11 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 386.0
HKD2_k127_3836269_12 peptidase S16 K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 339.0
HKD2_k127_3836269_13 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 339.0
HKD2_k127_3836269_14 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 317.0
HKD2_k127_3836269_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 319.0
HKD2_k127_3836269_17 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 289.0
HKD2_k127_3836269_18 YbaK prolyl-tRNA synthetase associated K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000001727 227.0
HKD2_k127_3836269_19 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
HKD2_k127_3836269_2 Major facilitator superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 601.0
HKD2_k127_3836269_20 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000003119 221.0
HKD2_k127_3836269_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000003853 190.0
HKD2_k127_3836269_22 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000001605 190.0
HKD2_k127_3836269_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000004013 184.0
HKD2_k127_3836269_24 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000006373 142.0
HKD2_k127_3836269_25 SPW repeat - - - 0.0000000000000000000000009479 108.0
HKD2_k127_3836269_26 - - - - 0.00000000000000000000005866 102.0
HKD2_k127_3836269_27 Belongs to the UPF0434 family K09791 - - 0.00000000000000000002963 97.0
HKD2_k127_3836269_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000005577 54.0
HKD2_k127_3836269_3 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 582.0
HKD2_k127_3836269_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 549.0
HKD2_k127_3836269_5 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 494.0
HKD2_k127_3836269_6 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 460.0
HKD2_k127_3836269_7 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 456.0
HKD2_k127_3836269_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 454.0
HKD2_k127_3836269_9 Tetratricopeptide repeat K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 424.0
HKD2_k127_3839478_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 466.0
HKD2_k127_3839478_1 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 331.0
HKD2_k127_3839478_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 324.0
HKD2_k127_3840163_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 546.0
HKD2_k127_3840163_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 540.0
HKD2_k127_3840163_10 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000001248 182.0
HKD2_k127_3840163_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 533.0
HKD2_k127_3840163_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 484.0
HKD2_k127_3840163_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 338.0
HKD2_k127_3840163_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
HKD2_k127_3840163_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000218 212.0
HKD2_k127_3840163_7 rRNA binding K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003884 213.0
HKD2_k127_3840163_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000003819 195.0
HKD2_k127_3840163_9 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000000000000000000000005316 193.0
HKD2_k127_385102_0 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 5.308e-201 641.0
HKD2_k127_385102_1 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000005683 180.0
HKD2_k127_385102_2 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000817 184.0
HKD2_k127_385102_3 FeS assembly SUF system protein - - - 0.00000000000000000000000000000000000000000005003 161.0
HKD2_k127_385102_4 TfoX N-terminal domain K07343 - - 0.000000000000000000000000007609 119.0
HKD2_k127_385102_5 - - - - 0.00000007742 54.0
HKD2_k127_3855301_0 AcrB/AcrD/AcrF family - - - 0.0 1333.0
HKD2_k127_3855301_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1168.0
HKD2_k127_3855301_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 364.0
HKD2_k127_3855301_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
HKD2_k127_3855301_12 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 306.0
HKD2_k127_3855301_13 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 304.0
HKD2_k127_3855301_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 291.0
HKD2_k127_3855301_15 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007653 268.0
HKD2_k127_3855301_16 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000004201 221.0
HKD2_k127_3855301_17 Single cache domain 3 - - - 0.00000000000000000000000000000000000000000000000000001347 193.0
HKD2_k127_3855301_18 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000000000004577 192.0
HKD2_k127_3855301_19 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000005207 160.0
HKD2_k127_3855301_2 amine oxidase - - - 1.014e-259 809.0
HKD2_k127_3855301_20 Protein of unknown function (DUF1761) - - - 0.00000000000000000000000000000000000001693 148.0
HKD2_k127_3855301_21 GtrA-like protein - - - 0.000000000000000000008461 99.0
HKD2_k127_3855301_22 Protein of unknown function (DUF1674) - - - 0.000000000000006343 76.0
HKD2_k127_3855301_23 Domain of unknown function (DUF202) K00389 - - 0.00004633 46.0
HKD2_k127_3855301_3 Periplasmic binding protein - - - 5.766e-254 806.0
HKD2_k127_3855301_4 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 619.0
HKD2_k127_3855301_5 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 597.0
HKD2_k127_3855301_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 477.0
HKD2_k127_3855301_7 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 456.0
HKD2_k127_3855301_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 369.0
HKD2_k127_3855301_9 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 353.0
HKD2_k127_3858473_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 610.0
HKD2_k127_3858473_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 479.0
HKD2_k127_3858473_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
HKD2_k127_3858473_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008368 280.0
HKD2_k127_3858473_4 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009668 244.0
HKD2_k127_3858473_5 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000006395 236.0
HKD2_k127_3858473_6 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000009675 160.0
HKD2_k127_3858473_7 - - - - 0.000000000000000000000000000000009319 131.0
HKD2_k127_3871255_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 2.998e-291 900.0
HKD2_k127_3871255_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0044237,GO:0044281 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 484.0
HKD2_k127_3871255_2 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 392.0
HKD2_k127_3871255_3 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 389.0
HKD2_k127_3871255_4 PFAM glutamate synthase alpha subunit domain protein K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001003 289.0
HKD2_k127_3871255_5 Pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004386 255.0
HKD2_k127_3871255_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
HKD2_k127_3871255_7 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000003744 138.0
HKD2_k127_3871255_8 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000002954 128.0
HKD2_k127_3871255_9 - - - - 0.000000000000000000000002618 103.0
HKD2_k127_3883886_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 612.0
HKD2_k127_3883886_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 589.0
HKD2_k127_3883886_10 COG2143 Thioredoxin-related protein K04084 - 1.8.1.8 0.0000000000000000000000002719 110.0
HKD2_k127_3883886_14 response regulator - - - 0.000001139 57.0
HKD2_k127_3883886_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 449.0
HKD2_k127_3883886_3 receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
HKD2_k127_3883886_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000005604 242.0
HKD2_k127_3883886_5 Protein of unknown function (DUF1007) - - - 0.00000000000000000000000000000000000000000000000000000000000000000276 235.0
HKD2_k127_3883886_6 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000003837 234.0
HKD2_k127_3883886_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000001754 170.0
HKD2_k127_3883886_8 Ras of Complex, Roc, domain of DAPkinase - - - 0.000000000000000000000000000000000001314 144.0
HKD2_k127_3883886_9 periplasmic solute binding protein K09815 - - 0.00000000000000000000000006286 111.0
HKD2_k127_3886777_0 cytochrome P450 - - - 2.413e-231 722.0
HKD2_k127_3886777_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 430.0
HKD2_k127_3886777_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 309.0
HKD2_k127_3886777_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 302.0
HKD2_k127_3886777_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004744 270.0
HKD2_k127_3886777_5 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000000000000000000000000004268 233.0
HKD2_k127_3887874_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.53e-301 940.0
HKD2_k127_3887874_1 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 479.0
HKD2_k127_3891738_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1116.0
HKD2_k127_3891738_1 PFAM acyl-CoA dehydrogenase K14448 - 1.3.8.12 5.152e-305 941.0
HKD2_k127_3891738_10 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 354.0
HKD2_k127_3891738_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 359.0
HKD2_k127_3891738_12 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 314.0
HKD2_k127_3891738_13 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD2_k127_3891738_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006131 267.0
HKD2_k127_3891738_15 Bacterial signalling protein N terminal repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000028 229.0
HKD2_k127_3891738_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000811 211.0
HKD2_k127_3891738_17 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003812 201.0
HKD2_k127_3891738_18 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000000000995 194.0
HKD2_k127_3891738_19 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000002124 196.0
HKD2_k127_3891738_2 reductase K00001,K14446 - 1.1.1.1,1.3.1.85 1.397e-259 805.0
HKD2_k127_3891738_20 UTP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000001168 207.0
HKD2_k127_3891738_21 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000008456 204.0
HKD2_k127_3891738_22 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000000000001568 194.0
HKD2_k127_3891738_23 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000364 159.0
HKD2_k127_3891738_24 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000003977 149.0
HKD2_k127_3891738_25 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000001162 137.0
HKD2_k127_3891738_26 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000004958 141.0
HKD2_k127_3891738_27 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000007888 128.0
HKD2_k127_3891738_3 - - - - 1.054e-240 769.0
HKD2_k127_3891738_31 PRC-barrel domain - - - 0.0000004117 59.0
HKD2_k127_3891738_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 604.0
HKD2_k127_3891738_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 571.0
HKD2_k127_3891738_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 567.0
HKD2_k127_3891738_7 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 563.0
HKD2_k127_3891738_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 472.0
HKD2_k127_3891738_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K19707 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 378.0
HKD2_k127_3894725_0 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 269.0
HKD2_k127_3894725_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000001107 116.0
HKD2_k127_3894725_2 Scp-like extracellular - - - 0.000000297 59.0
HKD2_k127_3899274_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.6e-235 736.0
HKD2_k127_3899274_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 504.0
HKD2_k127_3899274_10 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 310.0
HKD2_k127_3899274_11 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 315.0
HKD2_k127_3899274_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 311.0
HKD2_k127_3899274_13 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000518 266.0
HKD2_k127_3899274_14 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
HKD2_k127_3899274_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000008288 218.0
HKD2_k127_3899274_16 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.00000000000000000000000000000000000000000000143 174.0
HKD2_k127_3899274_17 protein tyrosine phosphatase - - - 0.000000000000000000000000000000000000000001337 163.0
HKD2_k127_3899274_18 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000001951 159.0
HKD2_k127_3899274_19 transcriptional regulator K13771,K13772 - - 0.000000000000000000000000000000000000001367 153.0
HKD2_k127_3899274_2 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 508.0
HKD2_k127_3899274_20 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000001461 122.0
HKD2_k127_3899274_21 Transglycosylase associated protein - - - 0.00000000000000000000000003123 113.0
HKD2_k127_3899274_22 LTXXQ motif family protein - - - 0.000000000000000000000004975 106.0
HKD2_k127_3899274_23 - - - - 0.00000000000000000001061 96.0
HKD2_k127_3899274_24 LTXXQ motif family protein - - - 0.000000000000000000292 94.0
HKD2_k127_3899274_25 - - - - 0.0000000000000000005438 91.0
HKD2_k127_3899274_28 PFAM Tetratricopeptide repeat - - - 0.00000009081 66.0
HKD2_k127_3899274_29 BA14K-like protein - - - 0.0000003129 61.0
HKD2_k127_3899274_3 Protein conserved in bacteria K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 505.0
HKD2_k127_3899274_30 Flp Fap pilin component K02651 - - 0.0008573 46.0
HKD2_k127_3899274_4 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 477.0
HKD2_k127_3899274_5 ABC transporter permease K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 475.0
HKD2_k127_3899274_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 435.0
HKD2_k127_3899274_7 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 417.0
HKD2_k127_3899274_8 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HKD2_k127_3899274_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 334.0
HKD2_k127_3914520_0 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 1.299e-281 875.0
HKD2_k127_3914520_1 cytochrome P450 - - - 6.18e-264 818.0
HKD2_k127_3914520_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000001002 206.0
HKD2_k127_3914520_11 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000747 216.0
HKD2_k127_3914520_12 COG0262 Dihydrofolate reductase - - - 0.000000000000000000000000000000000009511 143.0
HKD2_k127_3914520_13 - - - - 0.000000000000000000000000000002125 130.0
HKD2_k127_3914520_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 545.0
HKD2_k127_3914520_3 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 449.0
HKD2_k127_3914520_4 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 405.0
HKD2_k127_3914520_5 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 342.0
HKD2_k127_3914520_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 274.0
HKD2_k127_3914520_8 Formyl transferase K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002172 264.0
HKD2_k127_3914520_9 Belongs to the DnaA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006428 264.0
HKD2_k127_392316_0 TonB dependent receptor K16087 - - 3.886e-228 729.0
HKD2_k127_392316_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 392.0
HKD2_k127_392316_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000008587 123.0
HKD2_k127_392316_12 Phosphoribosyl transferase domain - - - 0.000000146 55.0
HKD2_k127_392316_2 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 384.0
HKD2_k127_392316_3 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000006722 223.0
HKD2_k127_392316_4 Haem utilisation ChuX/HutX K07227 - - 0.0000000000000000000000000000000000000000000000000000000000002478 224.0
HKD2_k127_392316_5 Alkaline phosphatase homologues K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000001257 208.0
HKD2_k127_392316_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000003568 200.0
HKD2_k127_392316_7 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000005731 215.0
HKD2_k127_392316_8 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000007501 183.0
HKD2_k127_392316_9 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000002999 137.0
HKD2_k127_3972533_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1373.0
HKD2_k127_3972533_1 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1088.0
HKD2_k127_3972533_10 sequence-specific DNA binding - - - 0.000000000000000000006887 102.0
HKD2_k127_3972533_12 - - - - 0.00000000001017 64.0
HKD2_k127_3972533_14 Tetratricopeptide repeat - - - 0.0009448 50.0
HKD2_k127_3972533_2 Peptidase M23 - - - 3.307e-222 711.0
HKD2_k127_3972533_3 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 2.773e-217 680.0
HKD2_k127_3972533_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 543.0
HKD2_k127_3972533_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 315.0
HKD2_k127_3972533_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 295.0
HKD2_k127_3972533_7 Domain of unknown function (DUF4167) - - - 0.000000000000000000000000000000000000000000002918 174.0
HKD2_k127_3972533_8 - - - - 0.00000000000000000000000000000000000001442 147.0
HKD2_k127_3972533_9 Domain of Unknown Function (DUF930) - - - 0.000000000000000000000000000000000001085 144.0
HKD2_k127_3985365_0 DEAD/H associated K03724 - - 0.0 1170.0
HKD2_k127_3985365_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 3.949e-277 863.0
HKD2_k127_3985365_10 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 336.0
HKD2_k127_3985365_11 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004986 264.0
HKD2_k127_3985365_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
HKD2_k127_3985365_13 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000002281 195.0
HKD2_k127_3985365_14 secondary thiamine-phosphate synthase - - - 0.000000000000000000000000000000000000000000000001297 181.0
HKD2_k127_3985365_15 Domain of unknown function (DUF4212) K14393 - - 0.00000000000000000000000000000000000000005144 152.0
HKD2_k127_3985365_16 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000002073 153.0
HKD2_k127_3985365_17 Protein of unknown function (DUF952) - - - 0.000000000000000000000000000000132 128.0
HKD2_k127_3985365_18 - - - - 0.00000000000000000000003284 101.0
HKD2_k127_3985365_19 Response regulator receiver - - - 0.000000000000000000001716 100.0
HKD2_k127_3985365_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.702e-210 672.0
HKD2_k127_3985365_20 - - - - 0.0000000000000000001189 95.0
HKD2_k127_3985365_21 Glycosyl transferase family group 2 - - - 0.0000001226 54.0
HKD2_k127_3985365_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 531.0
HKD2_k127_3985365_4 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 510.0
HKD2_k127_3985365_5 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 503.0
HKD2_k127_3985365_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 473.0
HKD2_k127_3985365_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 424.0
HKD2_k127_3985365_8 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 362.0
HKD2_k127_3985365_9 Sel1-like repeats. K07126,K13582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 379.0
HKD2_k127_3986005_0 GMC oxidoreductase - - - 2.246e-213 672.0
HKD2_k127_3986005_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 395.0
HKD2_k127_3986005_2 Protein of unknown function (DUF1013) K09987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 362.0
HKD2_k127_3986005_3 dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000001141 232.0
HKD2_k127_3987028_0 Nitrite reductase NAD(P)H , large subunit K00362 - 1.7.1.15 0.0 1480.0
HKD2_k127_3987028_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1295.0
HKD2_k127_3987028_10 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 373.0
HKD2_k127_3987028_11 ANTAR K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 334.0
HKD2_k127_3987028_12 COG0845 membrane-fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 320.0
HKD2_k127_3987028_13 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000008565 261.0
HKD2_k127_3987028_14 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.00000000000000000000000000000000000000000000000000000000006088 214.0
HKD2_k127_3987028_15 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000000000000000000000000002275 206.0
HKD2_k127_3987028_16 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000001753 198.0
HKD2_k127_3987028_17 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000003068 198.0
HKD2_k127_3987028_18 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000001038 179.0
HKD2_k127_3987028_19 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000003238 120.0
HKD2_k127_3987028_2 Cellulose synthase K00694 - 2.4.1.12 2.023e-263 826.0
HKD2_k127_3987028_20 PFAM Transglycosylase-associated protein - - - 0.0000000000000000004591 89.0
HKD2_k127_3987028_21 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000001025 69.0
HKD2_k127_3987028_3 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 2.516e-247 777.0
HKD2_k127_3987028_4 Major Facilitator Superfamily K02575 - - 1.141e-211 666.0
HKD2_k127_3987028_5 NMT1-like family K15576,K22067 - - 4.659e-205 643.0
HKD2_k127_3987028_6 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 570.0
HKD2_k127_3987028_7 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 513.0
HKD2_k127_3987028_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 513.0
HKD2_k127_3987028_9 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 454.0
HKD2_k127_3995804_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1419.0
HKD2_k127_3995804_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 3.386e-241 748.0
HKD2_k127_3995804_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 589.0
HKD2_k127_3995804_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 576.0
HKD2_k127_3995804_4 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 427.0
HKD2_k127_3995804_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 362.0
HKD2_k127_3995804_6 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
HKD2_k127_3995804_7 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006563 241.0
HKD2_k127_3995804_8 - - - - 0.000000000000000000000000000000000000000000000000000000000002133 222.0
HKD2_k127_3995804_9 Protein of unknown function (DUF992) - - - 0.00000000000000000000000000000000000000002151 158.0
HKD2_k127_4008322_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 578.0
HKD2_k127_4008322_1 TIGRFAM drug resistance transporter, Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 452.0
HKD2_k127_4008322_10 Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000004798 186.0
HKD2_k127_4008322_12 - - - - 0.0000000000001834 76.0
HKD2_k127_4008322_13 - - - - 0.0000000006843 67.0
HKD2_k127_4008322_14 Domain of unknown function (DUF892) - - - 0.00002216 53.0
HKD2_k127_4008322_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 369.0
HKD2_k127_4008322_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 348.0
HKD2_k127_4008322_4 Ion channel K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 311.0
HKD2_k127_4008322_5 GfdT protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009251 277.0
HKD2_k127_4008322_6 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009971 292.0
HKD2_k127_4008322_7 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002757 248.0
HKD2_k127_4008322_8 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000005296 227.0
HKD2_k127_4008322_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000007175 244.0
HKD2_k127_4011168_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.281e-230 718.0
HKD2_k127_4011168_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 2.361e-199 632.0
HKD2_k127_4011168_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000001651 79.0
HKD2_k127_4011168_11 Resolvase - - - 0.0000001815 53.0
HKD2_k127_4011168_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 559.0
HKD2_k127_4011168_3 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768,K01769 - 4.6.1.1,4.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 458.0
HKD2_k127_4011168_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
HKD2_k127_4011168_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
HKD2_k127_4011168_6 Belongs to the UPF0262 family - - - 0.000000000000000000000000000000000000000000000000000000000000004912 226.0
HKD2_k127_4011168_7 Low molecular weight phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000000000000000000005516 200.0
HKD2_k127_4011168_8 Protein of unknown function (DUF2948) - - - 0.00000000000000000000000000000000000000000000000009948 184.0
HKD2_k127_4011168_9 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001447 99.0
HKD2_k127_4027587_0 Leucyl/phenylalanyl-tRNA protein transferase K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 302.0
HKD2_k127_4027587_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000004846 66.0
HKD2_k127_4060764_0 His Kinase A (phospho-acceptor) domain K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 576.0
HKD2_k127_4060764_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 490.0
HKD2_k127_4060764_10 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000002062 118.0
HKD2_k127_4060764_11 Transglycosylase associated protein - - - 0.0000000000000000000000002814 107.0
HKD2_k127_4060764_13 epimerase dehydratase K08678 - 4.1.1.35 0.00005418 46.0
HKD2_k127_4060764_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
HKD2_k127_4060764_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 434.0
HKD2_k127_4060764_4 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
HKD2_k127_4060764_5 PFAM pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005164 262.0
HKD2_k127_4060764_6 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000004456 196.0
HKD2_k127_4060764_7 oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000104 190.0
HKD2_k127_4060764_8 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000008478 185.0
HKD2_k127_4060764_9 Sigma-54 interaction domain K07712 - - 0.00000000000000000000000000000000000000000005339 162.0
HKD2_k127_4068334_0 ABC transporter transmembrane region K06147,K18893 - - 3.619e-238 751.0
HKD2_k127_4068334_1 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 295.0
HKD2_k127_4069097_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.597e-239 747.0
HKD2_k127_4069097_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 569.0
HKD2_k127_4069097_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000003382 154.0
HKD2_k127_4069097_12 Outer membrane protein beta-barrel domain K16079 - - 0.0000000000000000000000000777 112.0
HKD2_k127_4069097_13 Evidence 4 Homologs of previously reported genes of - - - 0.00000000003493 72.0
HKD2_k127_4069097_14 - - - - 0.000000001528 70.0
HKD2_k127_4069097_15 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000001364 57.0
HKD2_k127_4069097_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 520.0
HKD2_k127_4069097_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 479.0
HKD2_k127_4069097_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 443.0
HKD2_k127_4069097_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 392.0
HKD2_k127_4069097_6 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 387.0
HKD2_k127_4069097_7 Putative beta-barrel porin 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 372.0
HKD2_k127_4069097_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004982 271.0
HKD2_k127_4069097_9 CHAD - - - 0.000000000000000000000000000000000000000000000000000000006527 211.0
HKD2_k127_4074070_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.311e-273 851.0
HKD2_k127_4074070_1 Glutathione S-transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HKD2_k127_4074070_2 - - - - 0.00000000000000000002426 93.0
HKD2_k127_4100707_0 transporter - - - 6.26e-235 736.0
HKD2_k127_4100707_1 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 1.189e-195 613.0
HKD2_k127_4100707_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 492.0
HKD2_k127_4100707_3 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 456.0
HKD2_k127_4100707_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 366.0
HKD2_k127_4100707_5 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000002565 231.0
HKD2_k127_4100707_6 succinate dehydrogenase K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000002629 177.0
HKD2_k127_4100707_7 Helix-turn-helix XRE-family like proteins K07726 - - 0.000000000000000000000001142 107.0
HKD2_k127_4100707_8 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000005251 89.0
HKD2_k127_4100707_9 Periplasmic protein thiol disulfide oxidoreductase K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000009532 86.0
HKD2_k127_4175443_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.9e-215 700.0
HKD2_k127_4175443_1 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 611.0
HKD2_k127_4175443_2 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 464.0
HKD2_k127_4175443_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
HKD2_k127_4175443_4 LTXXQ motif family protein - - - 0.00000000000000000000000002316 117.0
HKD2_k127_4179410_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1002.0
HKD2_k127_4179410_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 7.062e-246 767.0
HKD2_k127_4179410_10 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000003057 169.0
HKD2_k127_4179410_11 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000059 138.0
HKD2_k127_4179410_12 Transglycosylase associated protein - - - 0.000000000000000002234 89.0
HKD2_k127_4179410_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 8.299e-233 734.0
HKD2_k127_4179410_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 525.0
HKD2_k127_4179410_4 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 540.0
HKD2_k127_4179410_5 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 451.0
HKD2_k127_4179410_6 belongs to the carbohydrate kinase PfkB family K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 342.0
HKD2_k127_4179410_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 331.0
HKD2_k127_4179410_8 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002239 263.0
HKD2_k127_4179410_9 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000003301 170.0
HKD2_k127_4181475_0 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
HKD2_k127_4181475_1 HWE histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007259 301.0
HKD2_k127_4181475_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000397 226.0
HKD2_k127_4181475_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000005516 200.0
HKD2_k127_4181475_4 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000000003695 192.0
HKD2_k127_4181475_5 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000001287 104.0
HKD2_k127_4181475_6 PRC-barrel domain - - - 0.000000000000000000001884 104.0
HKD2_k127_4181475_7 - - - - 0.00000001294 60.0
HKD2_k127_4207225_0 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 562.0
HKD2_k127_4207225_1 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 453.0
HKD2_k127_4207225_11 transglycosylase - - - 0.00000000000001713 85.0
HKD2_k127_4207225_2 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 426.0
HKD2_k127_4207225_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 411.0
HKD2_k127_4207225_4 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 405.0
HKD2_k127_4207225_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 330.0
HKD2_k127_4207225_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001179 258.0
HKD2_k127_4207225_7 Sulfate ABC transporter inner membrane subunit CysW K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000002683 244.0
HKD2_k127_4207225_8 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000009122 126.0
HKD2_k127_4218989_0 Proton-conducting membrane transporter - - - 6.009e-292 909.0
HKD2_k127_4218989_1 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 402.0
HKD2_k127_4224503_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000007223 213.0
HKD2_k127_4224503_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000003183 213.0
HKD2_k127_4224503_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000001278 173.0
HKD2_k127_4224503_3 Aluminium activated malate transporter - - - 0.00000000000004083 81.0
HKD2_k127_4224503_4 Aromatic acid exporter family member 1 - - - 0.000000001287 69.0
HKD2_k127_4313998_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 2.339e-266 828.0
HKD2_k127_4313998_1 binding-protein-dependent transport systems inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 601.0
HKD2_k127_4313998_2 Binding-protein-dependent transport system inner membrane component K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 602.0
HKD2_k127_4313998_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 574.0
HKD2_k127_4313998_4 Extracellular solute-binding protein K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 413.0
HKD2_k127_4313998_5 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
HKD2_k127_4313998_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 296.0
HKD2_k127_4313998_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
HKD2_k127_4313998_8 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000004641 260.0
HKD2_k127_4323082_0 Protein of unknown function, DUF255 K06888 - - 2.683e-296 927.0
HKD2_k127_4323082_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 518.0
HKD2_k127_4323082_2 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 360.0
HKD2_k127_4323082_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000006547 90.0
HKD2_k127_4415022_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.359e-251 785.0
HKD2_k127_4415022_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 494.0
HKD2_k127_4415022_2 glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 346.0
HKD2_k127_4415022_3 GfdT protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 320.0
HKD2_k127_4415022_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003196 279.0
HKD2_k127_4415022_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001494 197.0
HKD2_k127_4464470_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 1.106e-272 846.0
HKD2_k127_4464470_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 595.0
HKD2_k127_4464470_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 534.0
HKD2_k127_4464470_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 439.0
HKD2_k127_4464470_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.000000000000000000000000000000000000000000000000000000000000001184 223.0
HKD2_k127_4488899_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0 1392.0
HKD2_k127_4488899_1 de-polymerase K05973 - 3.1.1.75 1.737e-199 630.0
HKD2_k127_4488899_2 AsmA-like C-terminal region K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 572.0
HKD2_k127_4488899_3 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 322.0
HKD2_k127_4488899_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000001258 229.0
HKD2_k127_4488899_5 cytochrome K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000001678 145.0
HKD2_k127_4488899_6 Phospholipid methyltransferase - - - 0.000000000000000000000000000000008239 132.0
HKD2_k127_4500339_0 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 379.0
HKD2_k127_4500339_1 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 286.0
HKD2_k127_4500339_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000003365 221.0
HKD2_k127_4500339_3 SOS response K14160 - - 0.000000000000006312 87.0
HKD2_k127_4576409_0 Transcriptional regulator K13635 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 476.0
HKD2_k127_4576409_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001518 200.0
HKD2_k127_4576409_2 GMC oxidoreductase K03333 - 1.1.3.6 0.00000000000000000000000897 105.0
HKD2_k127_4576409_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000008195 91.0
HKD2_k127_4576409_4 - - - - 0.000000000000001327 79.0
HKD2_k127_4576409_5 lysine exporter protein (LysE YggA) - - - 0.0007936 44.0
HKD2_k127_4580537_0 histidine kinase A domain protein - - - 0.0 2184.0
HKD2_k127_4580537_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000002469 171.0
HKD2_k127_4580537_2 HWE histidine kinase - - - 0.0000000000000000000000000000000000005671 158.0
HKD2_k127_458105_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000002248 184.0
HKD2_k127_458105_1 OmpA-like transmembrane domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000005305 53.0
HKD2_k127_458105_2 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0004005 46.0
HKD2_k127_4638529_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 601.0
HKD2_k127_4638529_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000442 211.0
HKD2_k127_47408_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 461.0
HKD2_k127_47408_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
HKD2_k127_47408_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 299.0
HKD2_k127_47408_3 PFAM Extensin family protein - - - 0.0000000000000000000000000000000000000000000000000000000002894 216.0
HKD2_k127_47408_4 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000178 203.0
HKD2_k127_47408_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000000001685 119.0
HKD2_k127_47408_6 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000001763 109.0
HKD2_k127_478550_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0 1148.0
HKD2_k127_478550_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 2.34e-247 771.0
HKD2_k127_478550_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 579.0
HKD2_k127_478550_3 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000121 175.0
HKD2_k127_478550_4 MAPEG family - - - 0.00000000000000000000000000000000000000000003719 165.0
HKD2_k127_478550_5 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000008932 155.0
HKD2_k127_478550_6 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000009708 125.0
HKD2_k127_478550_7 - - - - 0.0000000000000000000002184 100.0
HKD2_k127_4786024_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1304.0
HKD2_k127_4786024_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 544.0
HKD2_k127_4786024_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 429.0
HKD2_k127_4786024_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 362.0
HKD2_k127_4786024_4 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 330.0
HKD2_k127_4786024_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000006029 115.0
HKD2_k127_4786024_6 Thioredoxin - - - 0.00000000000000000000000008366 111.0
HKD2_k127_4795635_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1106.0
HKD2_k127_4795635_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 311.0
HKD2_k127_4795635_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000008615 134.0
HKD2_k127_483621_0 Periplasmic glucan biosynthesis protein, MdoG K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 503.0
HKD2_k127_499741_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 472.0
HKD2_k127_499741_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 337.0
HKD2_k127_499741_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000006741 242.0
HKD2_k127_5019439_0 phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1223.0
HKD2_k127_5019439_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 4.088e-222 704.0
HKD2_k127_5019439_10 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002664 126.0
HKD2_k127_5019439_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 4.778e-212 668.0
HKD2_k127_5019439_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 598.0
HKD2_k127_5019439_4 Lytic murein transglycosylase K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 494.0
HKD2_k127_5019439_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 467.0
HKD2_k127_5019439_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 284.0
HKD2_k127_5019439_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
HKD2_k127_5019439_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000001333 196.0
HKD2_k127_5019439_9 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000004025 154.0
HKD2_k127_5109429_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 379.0
HKD2_k127_5109429_1 exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 350.0
HKD2_k127_5111418_0 NLP P60 protein - - - 1.641e-293 915.0
HKD2_k127_5111418_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.694e-217 677.0
HKD2_k127_5111418_10 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000000007649 176.0
HKD2_k127_5111418_11 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000006194 178.0
HKD2_k127_5111418_12 Universal stress protein - - - 0.00000000000000000000000000000000000000000007109 165.0
HKD2_k127_5111418_13 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000195 153.0
HKD2_k127_5111418_14 glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000001151 147.0
HKD2_k127_5111418_15 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000001526 141.0
HKD2_k127_5111418_16 Cupredoxin-like domain - - - 0.0000000000000000000000000000006882 125.0
HKD2_k127_5111418_17 Polymer-forming cytoskeletal - - - 0.000000000000000000000000321 111.0
HKD2_k127_5111418_19 Protein involved in meta-pathway of phenol degradation - - - 0.000000000005262 75.0
HKD2_k127_5111418_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 558.0
HKD2_k127_5111418_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 340.0
HKD2_k127_5111418_4 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 304.0
HKD2_k127_5111418_5 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003257 284.0
HKD2_k127_5111418_6 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003361 271.0
HKD2_k127_5111418_7 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005121 255.0
HKD2_k127_5111418_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001418 244.0
HKD2_k127_5111418_9 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000006149 206.0
HKD2_k127_5156019_0 Belongs to the heme-copper respiratory oxidase family K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 9.433e-307 947.0
HKD2_k127_5156019_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 609.0
HKD2_k127_5156019_10 - - - - 0.00000000000000000000006497 104.0
HKD2_k127_5156019_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 437.0
HKD2_k127_5156019_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
HKD2_k127_5156019_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000235 225.0
HKD2_k127_5156019_5 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000002036 214.0
HKD2_k127_5156019_6 cytochrome C K00405 - - 0.0000000000000000000000000000000000000000000003693 168.0
HKD2_k127_5156019_7 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000718 173.0
HKD2_k127_5156019_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000959 162.0
HKD2_k127_5156019_9 - - - - 0.000000000000000000000000000000000000007525 152.0
HKD2_k127_5160707_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1170.0
HKD2_k127_5169543_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 1.647e-258 818.0
HKD2_k127_5169543_1 Cytochrome C oxidase accessory protein CcoG - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 8.144e-233 729.0
HKD2_k127_5169543_2 Belongs to the heme-copper respiratory oxidase family K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 589.0
HKD2_k127_5169543_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
HKD2_k127_5169543_4 cytochrome C K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 385.0
HKD2_k127_5169543_5 FixH - - - 0.000000000000000000000000000000000001523 149.0
HKD2_k127_5169543_6 Cytochrome oxidase maturation protein - - - 0.000000000000008873 79.0
HKD2_k127_5169543_7 Cbb3-type cytochrome oxidase K00407 - - 0.0000000006291 61.0
HKD2_k127_51822_0 cellulose binding - - - 4.743e-224 697.0
HKD2_k127_51822_1 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000005406 147.0
HKD2_k127_51822_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000000000005802 143.0
HKD2_k127_5208279_0 Signal transduction histidine kinase K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 616.0
HKD2_k127_5208279_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 507.0
HKD2_k127_5208279_10 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000005767 138.0
HKD2_k127_5208279_11 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.0000000000000000000002603 98.0
HKD2_k127_5208279_12 - - - - 0.00000000000000000002752 92.0
HKD2_k127_5208279_2 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 447.0
HKD2_k127_5208279_3 glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 383.0
HKD2_k127_5208279_4 pyridoxamine 5'-phosphate K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001387 274.0
HKD2_k127_5208279_5 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000756 276.0
HKD2_k127_5208279_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001309 264.0
HKD2_k127_5208279_7 Glutamine amido-transferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
HKD2_k127_5208279_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000006632 250.0
HKD2_k127_5208279_9 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000005378 210.0
HKD2_k127_5259199_0 Multi-copper - - - 4.997e-265 822.0
HKD2_k127_5259199_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.163e-212 674.0
HKD2_k127_5259199_10 CopC domain K07156 - - 0.00000000000000000000000000004168 120.0
HKD2_k127_5259199_11 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000005965 104.0
HKD2_k127_5259199_15 Protein of unknown function (DUF1059) - - - 0.0000168 51.0
HKD2_k127_5259199_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 599.0
HKD2_k127_5259199_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 500.0
HKD2_k127_5259199_4 Copper resistance protein D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 291.0
HKD2_k127_5259199_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001785 234.0
HKD2_k127_5259199_6 methylamine metabolic process K15977 - - 0.000000000000000000000000000000000000000000000000000000458 199.0
HKD2_k127_5259199_7 conserved protein UCP033924 - - - 0.0000000000000000000000000000000000000000000001007 176.0
HKD2_k127_5259199_8 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000002254 168.0
HKD2_k127_5259199_9 GYD domain - - - 0.0000000000000000000000000000000002674 134.0
HKD2_k127_5268768_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 2618.0
HKD2_k127_5268768_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.971e-258 801.0
HKD2_k127_5268768_2 Alpha beta hydrolase fold K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 415.0
HKD2_k127_5268768_3 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 412.0
HKD2_k127_5268768_4 inositol mono-phosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 329.0
HKD2_k127_5268768_5 Response regulator receiver K13589 - - 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
HKD2_k127_5268768_6 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000009647 203.0
HKD2_k127_5268768_7 Protein of unknown function (DUF459) K09795 - - 0.0000000000000000000000000000002704 126.0
HKD2_k127_5268768_8 Phage integrase family - - - 0.0000000002551 67.0
HKD2_k127_5304483_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1125.0
HKD2_k127_5304483_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 586.0
HKD2_k127_5304483_2 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000000000000001234 143.0
HKD2_k127_5328729_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 498.0
HKD2_k127_5328729_1 NAD-dependent K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 408.0
HKD2_k127_5328729_2 - - - - 0.00003383 49.0
HKD2_k127_5328729_3 KilA-N domain - - - 0.0002967 48.0
HKD2_k127_5367491_0 acetyltransferase - - - 0.0000000000000000000000002911 106.0
HKD2_k127_536941_0 serine threonine protein kinase K08282 - 2.7.11.1 8.017e-284 896.0
HKD2_k127_536941_1 oxidase subunit I K00425 - 1.10.3.14 3.965e-241 752.0
HKD2_k127_536941_2 oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 490.0
HKD2_k127_536941_3 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 336.0
HKD2_k127_536941_4 serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 290.0
HKD2_k127_536941_5 COG1716 FOG FHA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009649 271.0
HKD2_k127_536941_6 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005072 266.0
HKD2_k127_536941_7 Mg chelatase subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000001386 160.0
HKD2_k127_536941_8 Inner membrane component of T3SS, cytoplasmic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000004753 155.0
HKD2_k127_536986_0 poly(R)-hydroxyalkanoic acid synthase K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.281e-298 926.0
HKD2_k127_536986_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 2.187e-240 748.0
HKD2_k127_536986_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
HKD2_k127_536986_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 415.0
HKD2_k127_536986_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 402.0
HKD2_k127_536986_13 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 333.0
HKD2_k127_536986_14 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 317.0
HKD2_k127_536986_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 289.0
HKD2_k127_536986_16 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000111 208.0
HKD2_k127_536986_17 PFAM helix-turn-helix- domain containing protein AraC type K07506 - - 0.00000000000000000000000000000000000000000000000000003978 197.0
HKD2_k127_536986_18 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000000000002697 177.0
HKD2_k127_536986_19 intracellular protease amidase K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000005257 174.0
HKD2_k127_536986_2 Aminotransferase K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 3.416e-231 719.0
HKD2_k127_536986_20 helix_turn_helix, mercury resistance K13639 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000002492 158.0
HKD2_k127_536986_21 Cytochrome c - - - 0.0000000000000000000000000000000001673 138.0
HKD2_k127_536986_22 K COG2207 AraC-type DNA-binding domain-containing proteins K07506 - - 0.00000000000000000000000000692 114.0
HKD2_k127_536986_23 - - - - 0.000000000000000000000006149 109.0
HKD2_k127_536986_24 DJ-1/PfpI family K18199 - 4.2.1.103 0.00000000000000000000008262 104.0
HKD2_k127_536986_3 amino acid K03294 - - 1.003e-194 616.0
HKD2_k127_536986_4 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 599.0
HKD2_k127_536986_5 AMP-binding enzyme K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 581.0
HKD2_k127_536986_6 fructose-1,6-bisphosphatase K02446,K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 526.0
HKD2_k127_536986_7 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 521.0
HKD2_k127_536986_8 exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 509.0
HKD2_k127_536986_9 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 461.0
HKD2_k127_5394110_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1385.0
HKD2_k127_5394110_1 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000000002547 167.0
HKD2_k127_5403081_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 588.0
HKD2_k127_5439239_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1495.0
HKD2_k127_5439239_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 563.0
HKD2_k127_5439239_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 437.0
HKD2_k127_5439239_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 398.0
HKD2_k127_5439239_4 HlyD membrane-fusion protein of T1SS K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 348.0
HKD2_k127_5439239_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
HKD2_k127_5439239_6 Cellulose biosynthesis protein BcsS - - - 0.000000000000000000000000000000000000000000000000000000000001813 217.0
HKD2_k127_5439239_7 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000009513 175.0
HKD2_k127_5439239_8 Alpha beta hydrolase K03928 - 3.1.1.1 0.00000000000000000000000001206 111.0
HKD2_k127_5456265_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.002e-271 843.0
HKD2_k127_5456265_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 420.0
HKD2_k127_5456265_2 TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
HKD2_k127_5456265_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 417.0
HKD2_k127_5456265_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 376.0
HKD2_k127_5456265_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009777 253.0
HKD2_k127_5456265_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000006274 229.0
HKD2_k127_5456265_7 Short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000004284 171.0
HKD2_k127_5466858_0 FtsX-like permease family K02004 - - 9.837e-320 1012.0
HKD2_k127_5466858_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 330.0
HKD2_k127_5466858_2 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000005247 252.0
HKD2_k127_5466858_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000000000000005565 243.0
HKD2_k127_5466858_4 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000001261 151.0
HKD2_k127_5466858_5 Alcohol dehydrogenase zinc-binding K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000005024 132.0
HKD2_k127_5481945_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1041.0
HKD2_k127_5481945_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.299e-293 907.0
HKD2_k127_5481945_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
HKD2_k127_5481945_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 409.0
HKD2_k127_5481945_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000002497 222.0
HKD2_k127_5499538_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1011.0
HKD2_k127_5499538_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 436.0
HKD2_k127_5499538_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 335.0
HKD2_k127_5499538_3 Putative diguanylate phosphodiesterase K13593 - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
HKD2_k127_5529673_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 296.0
HKD2_k127_5529673_1 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008022 236.0
HKD2_k127_5529673_2 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000001187 218.0
HKD2_k127_5529673_3 Belongs to the ompA family - - - 0.000000000000002593 89.0
HKD2_k127_5529673_4 Heat shock protein DnaJ domain protein K05516 - - 0.00000000000308 79.0
HKD2_k127_5529673_5 light absorption - - - 0.000000009597 63.0
HKD2_k127_555712_0 Domain of unknown function DUF87 K06915 - - 9.845e-271 848.0
HKD2_k127_555712_1 major facilitator superfamily K03446 - - 3.348e-220 700.0
HKD2_k127_555712_10 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
HKD2_k127_555712_11 AefR-like transcriptional repressor, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000001684 205.0
HKD2_k127_555712_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000008117 185.0
HKD2_k127_555712_13 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000000000000000000000000003524 135.0
HKD2_k127_555712_14 CAAX protease self-immunity K01992,K07052,K09696 - - 0.0000000000000000000000000000001396 134.0
HKD2_k127_555712_15 Protein conserved in bacteria K09937 - - 0.0000000000000002721 81.0
HKD2_k127_555712_2 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 589.0
HKD2_k127_555712_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 551.0
HKD2_k127_555712_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 481.0
HKD2_k127_555712_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 452.0
HKD2_k127_555712_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 389.0
HKD2_k127_555712_7 HlyD membrane-fusion protein of T1SS K03543 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0042221,GO:0046677,GO:0050896,GO:0051716 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 374.0
HKD2_k127_555712_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 335.0
HKD2_k127_555712_9 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 321.0
HKD2_k127_5615993_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1381.0
HKD2_k127_5615993_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1210.0
HKD2_k127_5615993_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.312e-223 704.0
HKD2_k127_5615993_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 582.0
HKD2_k127_5615993_4 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 320.0
HKD2_k127_5615993_5 Scaffold protein Nfu NifU - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 310.0
HKD2_k127_5615993_6 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 293.0
HKD2_k127_5615993_7 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 238.0
HKD2_k127_5615993_8 chlorophyll binding K03286 - - 0.000000000000000000000000000000000000000000000000000000001582 213.0
HKD2_k127_5616892_0 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 462.0
HKD2_k127_5616892_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HKD2_k127_5616892_2 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 405.0
HKD2_k127_5616892_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 385.0
HKD2_k127_5616892_4 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
HKD2_k127_5616892_5 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000006025 225.0
HKD2_k127_5616892_6 Transposase - - - 0.000000000000000000000000001442 114.0
HKD2_k127_5616892_7 Recombinase zinc beta ribbon domain - - - 0.00000000004777 63.0
HKD2_k127_563780_0 His Kinase A (phosphoacceptor) domain - - - 6.669e-196 624.0
HKD2_k127_563780_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 592.0
HKD2_k127_563780_2 pyridine nucleotide-disulfide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 588.0
HKD2_k127_563780_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000002878 113.0
HKD2_k127_563780_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000004047 73.0
HKD2_k127_5655275_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 542.0
HKD2_k127_5655275_1 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 304.0
HKD2_k127_5661329_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1197.0
HKD2_k127_5661329_1 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 454.0
HKD2_k127_5661329_2 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 387.0
HKD2_k127_5661329_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
HKD2_k127_5661329_4 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 341.0
HKD2_k127_5661329_5 Pentapeptide repeat protein K15352 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 311.0
HKD2_k127_5661329_6 Extensin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
HKD2_k127_5661329_7 Protein of unknown function (DUF2852) - - - 0.0000000000000000000000000000000000000000000000001852 179.0
HKD2_k127_5661329_8 Zinc-finger domain - - - 0.0000000000000000000000000000000000001338 142.0
HKD2_k127_5661329_9 Protein of unknown function (DUF2852) - - - 0.0000000000000000003503 91.0
HKD2_k127_5663392_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 4.789e-200 631.0
HKD2_k127_5663392_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 527.0
HKD2_k127_5663392_2 Aminotransferase class I and II K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 501.0
HKD2_k127_5663392_3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
HKD2_k127_5663392_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002056 265.0
HKD2_k127_5663392_5 Transcriptional regulator GntR family K03710 - - 0.000000000000000000000000000000000000000000000000007315 189.0
HKD2_k127_570219_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 389.0
HKD2_k127_570219_1 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 314.0
HKD2_k127_570219_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003525 240.0
HKD2_k127_570219_3 Polysaccharide deacetylase - - - 0.000000000000000000000000003609 117.0
HKD2_k127_570219_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000004047 73.0
HKD2_k127_5707118_0 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 444.0
HKD2_k127_5707118_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000001384 167.0
HKD2_k127_5707118_2 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000007463 126.0
HKD2_k127_5707118_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000008282 57.0
HKD2_k127_5707118_4 Protein of unknown function (DUF992) - - - 0.0000003246 61.0
HKD2_k127_5736222_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1275.0
HKD2_k127_5736222_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 503.0
HKD2_k127_5736222_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 402.0
HKD2_k127_5736222_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 271.0
HKD2_k127_5736222_4 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000000000000000000000004774 234.0
HKD2_k127_5736222_5 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000009483 138.0
HKD2_k127_5736222_6 BolA-like protein - - - 0.000000000000000000000000000000002825 129.0
HKD2_k127_5736222_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000002906 121.0
HKD2_k127_5736222_8 - - - - 0.0000000002363 68.0
HKD2_k127_5772376_0 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 7.458e-278 881.0
HKD2_k127_5772376_1 belongs to the aldehyde dehydrogenase family K00138 - - 1.429e-271 844.0
HKD2_k127_5772376_10 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002004 266.0
HKD2_k127_5772376_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000003824 256.0
HKD2_k127_5772376_12 Glycosyl transferases group 1 K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002046 259.0
HKD2_k127_5772376_13 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008259 254.0
HKD2_k127_5772376_14 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000002996 233.0
HKD2_k127_5772376_15 Protein of unknown function (DUF779) K09959 - - 0.000000000000000000000000000000000000000000000000000000001054 205.0
HKD2_k127_5772376_16 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000002908 196.0
HKD2_k127_5772376_17 - - - - 0.00000000000000000000000000000000000000003474 159.0
HKD2_k127_5772376_18 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000006769 149.0
HKD2_k127_5772376_19 - - - - 0.000000000008229 68.0
HKD2_k127_5772376_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.905e-233 734.0
HKD2_k127_5772376_20 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000002042 53.0
HKD2_k127_5772376_21 Cytochrome c K08738 - - 0.00003852 47.0
HKD2_k127_5772376_3 biosynthesis protein - GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - 1.233e-225 719.0
HKD2_k127_5772376_4 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
HKD2_k127_5772376_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 418.0
HKD2_k127_5772376_6 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 376.0
HKD2_k127_5772376_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 371.0
HKD2_k127_5772376_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 363.0
HKD2_k127_5772376_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 342.0
HKD2_k127_584382_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1419.0
HKD2_k127_584382_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.457e-296 918.0
HKD2_k127_584382_2 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 2.101e-252 790.0
HKD2_k127_584382_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 3.021e-198 625.0
HKD2_k127_584382_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 561.0
HKD2_k127_584382_5 NADH-quinone oxidoreductase chain K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 549.0
HKD2_k127_584382_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 312.0
HKD2_k127_584382_7 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000008023 241.0
HKD2_k127_584382_8 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000005515 261.0
HKD2_k127_584382_9 Protein of unknown function (DUF1467) - - - 0.0000000000000003082 83.0
HKD2_k127_5931442_0 Mg chelatase subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 517.0
HKD2_k127_5931442_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 431.0
HKD2_k127_5931442_2 YGGT family K02221 - - 0.000000000000000000000000000001147 127.0
HKD2_k127_5931442_3 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000341 114.0
HKD2_k127_5931442_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000003346 90.0
HKD2_k127_6048358_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000009488 217.0
HKD2_k127_6048358_1 Outer membrane efflux protein K12340 - - 0.000000004335 58.0
HKD2_k127_6048358_2 - K08086,K09991 - - 0.00001888 56.0
HKD2_k127_6048644_0 Catalyzes the NAD( )-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non- methylotrophic organisms K00122 - 1.17.1.9 2.042e-223 699.0
HKD2_k127_6048644_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
HKD2_k127_6048644_2 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000003754 175.0
HKD2_k127_6064074_0 GTP-binding protein K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0 1045.0
HKD2_k127_6064074_1 Helicase - - - 1.908e-207 653.0
HKD2_k127_6064074_2 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002781 242.0
HKD2_k127_6064074_3 Phasin protein - - - 0.00000000000000000000000000000000000000000002547 167.0
HKD2_k127_6064074_4 Peptidase propeptide and YPEB domain - - - 0.00000005841 56.0
HKD2_k127_6065247_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 7.824e-243 754.0
HKD2_k127_6065247_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 312.0
HKD2_k127_6065247_2 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 284.0
HKD2_k127_6065247_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000006184 129.0
HKD2_k127_6129861_0 Protein of unknown function - - - 0.0 1110.0
HKD2_k127_6129861_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002259 242.0
HKD2_k127_6129861_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000008623 190.0
HKD2_k127_6129861_3 ATPase involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000002648 200.0
HKD2_k127_6384442_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1113.0
HKD2_k127_6403349_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 535.0
HKD2_k127_6403349_1 Belongs to the protein N5-glutamine methyltransferase family K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 436.0
HKD2_k127_6430531_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1501.0
HKD2_k127_6430531_1 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 591.0
HKD2_k127_6430531_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 531.0
HKD2_k127_6430531_3 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 526.0
HKD2_k127_6430531_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 466.0
HKD2_k127_6430531_5 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 375.0
HKD2_k127_6430531_6 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000006397 229.0
HKD2_k127_6433678_0 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 451.0
HKD2_k127_6433678_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006637 415.0
HKD2_k127_6433678_2 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 344.0
HKD2_k127_6433678_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000001243 209.0
HKD2_k127_6433678_4 MerR HTH family regulatory protein K18997 - - 0.000000000000000000003927 96.0
HKD2_k127_6439042_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 330.0
HKD2_k127_6439042_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004789 259.0
HKD2_k127_6439042_2 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000001779 219.0
HKD2_k127_6439042_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000001464 182.0
HKD2_k127_6442541_0 Heat shock 70 kDa protein K04043 - - 0.0 1095.0
HKD2_k127_6442541_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 565.0
HKD2_k127_6442541_10 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 368.0
HKD2_k127_6442541_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 348.0
HKD2_k127_6442541_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 342.0
HKD2_k127_6442541_13 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 312.0
HKD2_k127_6442541_14 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 317.0
HKD2_k127_6442541_15 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 295.0
HKD2_k127_6442541_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HKD2_k127_6442541_17 protein conserved in bacteria K09974 - - 0.00000000000000000000000000000000000000000000000000000000000000009531 237.0
HKD2_k127_6442541_18 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000002118 222.0
HKD2_k127_6442541_19 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000001919 211.0
HKD2_k127_6442541_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 545.0
HKD2_k127_6442541_20 Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000000000000000000000000002937 198.0
HKD2_k127_6442541_21 - - - - 0.000000000000000000000000000000000000000000000000000003224 196.0
HKD2_k127_6442541_22 Domain of unknown function (DUF1772) - - - 0.000000000000000000000000000000000000000001424 162.0
HKD2_k127_6442541_23 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000002431 148.0
HKD2_k127_6442541_24 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000002702 146.0
HKD2_k127_6442541_25 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000002208 127.0
HKD2_k127_6442541_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 539.0
HKD2_k127_6442541_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 469.0
HKD2_k127_6442541_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 437.0
HKD2_k127_6442541_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 388.0
HKD2_k127_6442541_7 LppC putative lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 395.0
HKD2_k127_6442541_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 375.0
HKD2_k127_6442541_9 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 363.0
HKD2_k127_6485635_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 482.0
HKD2_k127_6485635_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 459.0
HKD2_k127_6485635_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 462.0
HKD2_k127_6485635_3 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 449.0
HKD2_k127_6485635_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 362.0
HKD2_k127_6485635_5 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 349.0
HKD2_k127_6485635_6 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000003021 180.0
HKD2_k127_6485635_7 - - - - 0.00000002759 59.0
HKD2_k127_6493699_0 PFAM amino acid permease-associated region K03294 - - 6.721e-226 717.0
HKD2_k127_6493699_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 512.0
HKD2_k127_6493699_2 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 466.0
HKD2_k127_6493699_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000006299 197.0
HKD2_k127_6493699_4 - - - - 0.00000000000000000000000000000000002946 138.0
HKD2_k127_6493699_6 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000007072 65.0
HKD2_k127_6497343_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 578.0
HKD2_k127_6497343_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 503.0
HKD2_k127_6497343_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 346.0
HKD2_k127_6497343_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009191 280.0
HKD2_k127_6497343_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000001104 248.0
HKD2_k127_6497343_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000001068 237.0
HKD2_k127_6497343_6 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000000003765 177.0
HKD2_k127_6497343_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000004831 112.0
HKD2_k127_6497343_8 Protein of unknown function (DUF423) - - - 0.0000000000000000006188 91.0
HKD2_k127_6508534_0 glucose-6-phosphate isomerase activity K01810 - 5.3.1.9 5.93e-244 763.0
HKD2_k127_6508534_1 Thiol oxidoreductase - - - 1.35e-217 681.0
HKD2_k127_6508534_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 464.0
HKD2_k127_6508534_3 Choloylglycine hydrolase K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 439.0
HKD2_k127_6508534_4 50S ribosome-binding GTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 435.0
HKD2_k127_6508534_5 50S ribosome-binding GTPase K06946 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 406.0
HKD2_k127_6508534_6 Protein of unknown function (DUF1097) - - - 0.0000000000000000000000000000000000000000000000001943 183.0
HKD2_k127_6508534_7 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000002059 82.0
HKD2_k127_6525322_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606,K20997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 610.0
HKD2_k127_6525322_1 Imelysin K07231 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 560.0
HKD2_k127_6525322_2 O-Antigen ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 414.0
HKD2_k127_6525322_3 Protein of unknown function (DUF1513) K09947 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 394.0
HKD2_k127_6525322_4 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 378.0
HKD2_k127_6525322_5 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003641 271.0
HKD2_k127_6525322_6 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
HKD2_k127_6525322_7 Imelysin K07338 - - 0.00000000000000000000000006131 120.0
HKD2_k127_6525322_8 Thiol oxidoreductase - - - 0.000000000000000005993 87.0
HKD2_k127_6541622_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1697.0
HKD2_k127_6541622_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 415.0
HKD2_k127_6541622_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001732 267.0
HKD2_k127_6541622_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001061 241.0
HKD2_k127_6590_0 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 491.0
HKD2_k127_6590_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 486.0
HKD2_k127_6590_10 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000000000000000000000001089 185.0
HKD2_k127_6590_11 Clp amino terminal domain, pathogenicity island component - - - 0.00000000000000000000000000000000000000000006937 172.0
HKD2_k127_6590_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000102 152.0
HKD2_k127_6590_13 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000003135 127.0
HKD2_k127_6590_14 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000003137 101.0
HKD2_k127_6590_15 Bacterial protein of unknown function (DUF899) - - - 0.0000000002002 62.0
HKD2_k127_6590_2 Electron transfer flavoprotein, alpha subunit K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 440.0
HKD2_k127_6590_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 421.0
HKD2_k127_6590_4 Pyrimidine 5'-nucleotidase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
HKD2_k127_6590_5 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005257 259.0
HKD2_k127_6590_6 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001505 255.0
HKD2_k127_6590_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
HKD2_k127_6590_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000009912 203.0
HKD2_k127_6590_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000002952 189.0
HKD2_k127_6598041_0 TonB dependent receptor - - - 1.371e-249 795.0
HKD2_k127_6598041_1 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 266.0
HKD2_k127_6598041_2 TonB dependent receptor - - - 0.0000000000003194 72.0
HKD2_k127_6598041_3 Sigma-70 region 2 - - - 0.0000003407 59.0
HKD2_k127_6626203_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 7.132e-233 729.0
HKD2_k127_6644882_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1031.0
HKD2_k127_6644882_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003658 255.0
HKD2_k127_6644882_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000000000000000008789 98.0
HKD2_k127_6644882_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000002476 67.0
HKD2_k127_6644882_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000002971 55.0
HKD2_k127_6675765_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 361.0
HKD2_k127_6675765_1 PFAM peptidase U6 penicillin-insensitive murein endopeptidase K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 350.0
HKD2_k127_6675765_3 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000001745 168.0
HKD2_k127_6675765_4 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000314 164.0
HKD2_k127_6708335_0 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 387.0
HKD2_k127_6708335_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 356.0
HKD2_k127_6708335_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001166 218.0
HKD2_k127_6708335_3 Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000000008535 213.0
HKD2_k127_6708335_5 TIGRFAM protein TolA K03646 - - 0.000000000000002489 79.0
HKD2_k127_6727871_0 ABC transporter K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 2.272e-266 832.0
HKD2_k127_6727871_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000005047 145.0
HKD2_k127_6727871_2 - - - - 0.0002427 46.0
HKD2_k127_6749528_0 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 503.0
HKD2_k127_6749528_1 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0042802,GO:0044237 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 417.0
HKD2_k127_6749528_11 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000000000000000001931 190.0
HKD2_k127_6749528_12 alpha beta - - - 0.0000000000000000000000000000004564 136.0
HKD2_k127_6749528_2 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 432.0
HKD2_k127_6749528_3 response regulator K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 339.0
HKD2_k127_6749528_4 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 328.0
HKD2_k127_6749528_5 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 312.0
HKD2_k127_6749528_6 Protein tyrosine serine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
HKD2_k127_6749528_7 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 263.0
HKD2_k127_6749528_8 protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
HKD2_k127_6749528_9 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000001033 211.0
HKD2_k127_6762939_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 601.0
HKD2_k127_6762939_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 494.0
HKD2_k127_6762939_2 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 470.0
HKD2_k127_6762939_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 411.0
HKD2_k127_6762939_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 390.0
HKD2_k127_6762939_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
HKD2_k127_6762939_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 362.0
HKD2_k127_6762939_7 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 336.0
HKD2_k127_6762939_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 287.0
HKD2_k127_6762939_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HKD2_k127_6774469_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 2.188e-309 964.0
HKD2_k127_6774469_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 3.423e-241 758.0
HKD2_k127_6774469_10 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 390.0
HKD2_k127_6774469_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 349.0
HKD2_k127_6774469_12 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 330.0
HKD2_k127_6774469_13 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 313.0
HKD2_k127_6774469_14 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 286.0
HKD2_k127_6774469_15 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
HKD2_k127_6774469_16 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001007 273.0
HKD2_k127_6774469_17 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002038 245.0
HKD2_k127_6774469_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000914 203.0
HKD2_k127_6774469_19 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000001091 197.0
HKD2_k127_6774469_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 4.224e-238 743.0
HKD2_k127_6774469_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000002305 173.0
HKD2_k127_6774469_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000002218 188.0
HKD2_k127_6774469_22 Universal stress protein family - - - 0.000000000000000000000000000000000000000001205 160.0
HKD2_k127_6774469_23 COG1544 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000000000000000005533 131.0
HKD2_k127_6774469_24 ChaB K06197 - - 0.000000000000000000000000004188 111.0
HKD2_k127_6774469_25 - - - - 0.0000000000000000000000059 104.0
HKD2_k127_6774469_26 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.00000000000005362 72.0
HKD2_k127_6774469_27 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000007223 70.0
HKD2_k127_6774469_28 cyclic nucleotide binding K01420 - - 0.0000000001 67.0
HKD2_k127_6774469_29 - - - - 0.0000001517 58.0
HKD2_k127_6774469_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 584.0
HKD2_k127_6774469_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 542.0
HKD2_k127_6774469_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 514.0
HKD2_k127_6774469_6 ErfK YbiS YcfS YnhG family protein K21470,K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 521.0
HKD2_k127_6774469_7 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 458.0
HKD2_k127_6774469_8 secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 435.0
HKD2_k127_6774469_9 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 427.0
HKD2_k127_6809653_0 PFAM cytochrome c, class I - - - 0.00000000007717 63.0
HKD2_k127_6852909_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 601.0
HKD2_k127_6852909_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 572.0
HKD2_k127_6852909_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 304.0
HKD2_k127_6852909_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007197 267.0
HKD2_k127_6852909_4 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001495 222.0
HKD2_k127_6852909_7 - - - - 0.000000000001037 70.0
HKD2_k127_6875624_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000004225 247.0
HKD2_k127_6875624_1 Response regulator receiver - - - 0.00000000000000000207 90.0
HKD2_k127_6875624_2 Glycosyltransferase Family 4 - - - 0.0001603 46.0
HKD2_k127_6904840_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1824.0
HKD2_k127_6904840_1 ABC transporter K15738 - - 0.0 998.0
HKD2_k127_6904840_10 Cupin - - - 0.00000000000000000000000000000000000000000001528 169.0
HKD2_k127_6904840_13 PIN domain - - - 0.0000000000000000000003212 100.0
HKD2_k127_6904840_14 Plasmid stability protein K21495 - - 0.0001216 51.0
HKD2_k127_6904840_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 3.232e-219 685.0
HKD2_k127_6904840_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 437.0
HKD2_k127_6904840_4 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 371.0
HKD2_k127_6904840_5 Patatin phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000168 280.0
HKD2_k127_6904840_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009994 267.0
HKD2_k127_6904840_7 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004228 259.0
HKD2_k127_6904840_8 Abortive infection protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
HKD2_k127_6904840_9 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000003564 180.0
HKD2_k127_6929910_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 404.0
HKD2_k127_6929910_1 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 331.0
HKD2_k127_6980388_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 2.987e-225 704.0
HKD2_k127_6980388_1 cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 368.0
HKD2_k127_6980388_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000001892 254.0
HKD2_k127_6980388_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000006493 63.0
HKD2_k127_6984064_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 466.0
HKD2_k127_6984064_1 Sodium:solute symporter family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 298.0
HKD2_k127_711745_0 P-type ATPase' K17686 - 3.6.3.54 0.0 1147.0
HKD2_k127_711745_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 3.663e-224 698.0
HKD2_k127_711745_10 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
HKD2_k127_711745_11 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 293.0
HKD2_k127_711745_12 Bacterial SH3 domain homologues K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000005244 243.0
HKD2_k127_711745_13 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000000000000000415 212.0
HKD2_k127_711745_14 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000002379 201.0
HKD2_k127_711745_16 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000007476 129.0
HKD2_k127_711745_17 Domain of unknown function (DUF4189) - - - 0.00000009441 61.0
HKD2_k127_711745_2 D-isomer specific 2-hydroxyacid dehydrogenase K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 598.0
HKD2_k127_711745_3 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 559.0
HKD2_k127_711745_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 532.0
HKD2_k127_711745_5 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 520.0
HKD2_k127_711745_6 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 476.0
HKD2_k127_711745_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 428.0
HKD2_k127_711745_8 UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 388.0
HKD2_k127_711745_9 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 314.0
HKD2_k127_7150896_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 3.883e-195 613.0
HKD2_k127_7150896_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 612.0
HKD2_k127_7150896_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000006068 75.0
HKD2_k127_7203461_0 Zinc-binding dehydrogenase K00344 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 464.0
HKD2_k127_7203461_1 Methyltransferase K13623 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
HKD2_k127_7203461_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
HKD2_k127_7203461_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000002684 116.0
HKD2_k127_736768_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 613.0
HKD2_k127_736768_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 368.0
HKD2_k127_736768_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 318.0
HKD2_k127_736768_3 GCN5-related N-acetyltransferase - - - 0.0000000000009377 68.0
HKD2_k127_7374749_0 histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 478.0
HKD2_k127_7374749_1 Short-chain dehydrogenase reductase SDR K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 393.0
HKD2_k127_7374749_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000001327 175.0
HKD2_k127_7374749_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000000000001895 139.0
HKD2_k127_7374749_4 - - - - 0.0000000000000001911 79.0
HKD2_k127_7374749_5 - - - - 0.0006651 43.0
HKD2_k127_7498618_0 succinylglutamate desuccinylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 376.0
HKD2_k127_7498618_1 - - - - 0.000000000000000000000000000000000000000009788 160.0
HKD2_k127_7498618_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000001314 115.0
HKD2_k127_7498618_3 AsmA-like C-terminal region K07289 - - 0.000000000000000000114 104.0
HKD2_k127_7527039_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5e-323 999.0
HKD2_k127_7527039_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 506.0
HKD2_k127_756931_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 2.736e-272 861.0
HKD2_k127_756931_1 cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
HKD2_k127_756931_2 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003027 278.0
HKD2_k127_756931_3 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000164 252.0
HKD2_k127_756931_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000003423 229.0
HKD2_k127_756931_5 Dodecin K09165 - - 0.0000000000000000005882 88.0
HKD2_k127_7582890_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
HKD2_k127_7582890_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 437.0
HKD2_k127_7582890_2 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 346.0
HKD2_k127_7582890_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 294.0
HKD2_k127_7582890_4 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000003472 57.0
HKD2_k127_7595113_0 lipid A ABC exporter family, fused ATPase and inner membrane subunits K06147 - - 4.116e-239 754.0
HKD2_k127_7595113_1 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 532.0
HKD2_k127_7595113_10 Protein of unknown function (DUF1465) K13592 - - 0.000000000000000000000000000000000000000000000000000000213 201.0
HKD2_k127_7595113_11 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000005387 178.0
HKD2_k127_7595113_12 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000003387 169.0
HKD2_k127_7595113_13 ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000000206 144.0
HKD2_k127_7595113_14 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000482 128.0
HKD2_k127_7595113_15 Protein of unknown function (DUF1192) - - - 0.0000000000000007312 79.0
HKD2_k127_7595113_16 - - - - 0.0000000003152 63.0
HKD2_k127_7595113_2 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 515.0
HKD2_k127_7595113_3 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 489.0
HKD2_k127_7595113_4 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
HKD2_k127_7595113_5 amidase activity K01448,K02395,K17733 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 406.0
HKD2_k127_7595113_6 inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 396.0
HKD2_k127_7595113_7 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 366.0
HKD2_k127_7595113_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 365.0
HKD2_k127_7595113_9 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 302.0
HKD2_k127_7675404_0 Sulfatase - - - 5.043e-233 728.0
HKD2_k127_7675404_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.433e-228 710.0
HKD2_k127_7675404_11 Small multidrug resistance protein K11741 - - 0.000000000000000000000001663 106.0
HKD2_k127_7675404_12 Protein of unknown function (DUF2628) - - - 0.00000000000000000000134 105.0
HKD2_k127_7675404_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 4.863e-200 629.0
HKD2_k127_7675404_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
HKD2_k127_7675404_4 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 361.0
HKD2_k127_7675404_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
HKD2_k127_7675404_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 310.0
HKD2_k127_7675404_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000004401 252.0
HKD2_k127_7675404_8 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000002165 208.0
HKD2_k127_7684805_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.415e-305 940.0
HKD2_k127_7684805_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 564.0
HKD2_k127_7684805_2 Cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 488.0
HKD2_k127_7684805_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 447.0
HKD2_k127_7684805_4 SURF1 family K14998 GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000005429 244.0
HKD2_k127_7684805_5 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
HKD2_k127_7684805_6 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000002244 158.0
HKD2_k127_7684805_7 - - - - 0.00000113 52.0
HKD2_k127_7694478_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1076.0
HKD2_k127_7694478_1 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 2.911e-256 809.0
HKD2_k127_7694478_10 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
HKD2_k127_7694478_11 receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 324.0
HKD2_k127_7694478_12 phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 311.0
HKD2_k127_7694478_13 Protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009357 254.0
HKD2_k127_7694478_14 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000004412 167.0
HKD2_k127_7694478_15 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000002571 151.0
HKD2_k127_7694478_2 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 8.453e-223 694.0
HKD2_k127_7694478_3 receptor K02014 - - 6.672e-197 639.0
HKD2_k127_7694478_4 LuxR family transcriptional regulator K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 603.0
HKD2_k127_7694478_5 amine oxidase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 539.0
HKD2_k127_7694478_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 466.0
HKD2_k127_7694478_7 Hopene-associated glycosyltransferase HpnB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 458.0
HKD2_k127_7694478_8 Nad-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 448.0
HKD2_k127_7694478_9 squalene synthase HpnC K21678,K21679 - 2.5.1.103,4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 347.0
HKD2_k127_7728179_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1122.0
HKD2_k127_7728179_1 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 442.0
HKD2_k127_7728179_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000007237 197.0
HKD2_k127_7728179_11 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000005967 179.0
HKD2_k127_7728179_12 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000000000000000000000003419 177.0
HKD2_k127_7728179_13 PAS domain - - - 0.0000000000000000000000000000000000000000000000841 177.0
HKD2_k127_7728179_14 Cupin domain - - - 0.000000000000000000000000000000000000000000001266 170.0
HKD2_k127_7728179_15 PilZ domain - - - 0.000000000000000000000000000000000000000000112 168.0
HKD2_k127_7728179_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000002896 158.0
HKD2_k127_7728179_17 Protein of unknown function (DUF3126) - - - 0.0000000000000000000003361 104.0
HKD2_k127_7728179_2 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 439.0
HKD2_k127_7728179_3 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 379.0
HKD2_k127_7728179_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HKD2_k127_7728179_5 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 306.0
HKD2_k127_7728179_6 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
HKD2_k127_7728179_7 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009328 250.0
HKD2_k127_7728179_8 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000002547 246.0
HKD2_k127_7728179_9 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
HKD2_k127_7759384_0 Cupin K01569 - 4.1.1.2 1.484e-204 644.0
HKD2_k127_7759384_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 538.0
HKD2_k127_7759384_10 - - - - 0.00000000000003556 76.0
HKD2_k127_7759384_2 two component transcriptional regulator K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 451.0
HKD2_k127_7759384_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 341.0
HKD2_k127_7759384_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 330.0
HKD2_k127_7759384_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
HKD2_k127_7759384_6 Protein of unknown function (DUF1153) - - - 0.000000000000000000000000000000000000000000000000000103 187.0
HKD2_k127_7759384_7 - - - - 0.0000000000000000000000000000000000000000000008123 169.0
HKD2_k127_7759384_8 flagellar export protein FliJ - - - 0.000000000000000000000000000000000000000008732 158.0
HKD2_k127_7766385_0 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 5.058e-271 836.0
HKD2_k127_7766385_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 347.0
HKD2_k127_7766385_2 DoxX-like family K15977 - - 0.00000000000000000000000000000000000000000000000000000000000000000001733 235.0
HKD2_k127_7766385_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000005098 216.0
HKD2_k127_7766385_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000001899 218.0
HKD2_k127_7766385_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000001031 181.0
HKD2_k127_7766385_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000007472 175.0
HKD2_k127_7766385_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000001832 100.0
HKD2_k127_7766385_8 Protein of unknown function (DUF3300) - - - 0.00000000000000000002541 102.0
HKD2_k127_7772342_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.095e-225 703.0
HKD2_k127_7772342_1 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.00000000000000000000000000000000000000000000000287 177.0
HKD2_k127_7785901_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 607.0
HKD2_k127_7785901_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
HKD2_k127_7785901_2 glutamate-ammonia ligase activity - - - 0.000000000000000000000004294 114.0
HKD2_k127_7785901_3 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000006477 77.0
HKD2_k127_7785901_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000002865 67.0
HKD2_k127_7788939_0 NADH ubiquinone oxidoreductase 17.2 kD subunit K00356 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000001007 230.0
HKD2_k127_7788939_1 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000000006286 200.0
HKD2_k127_7788939_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000222 77.0
HKD2_k127_7788939_3 LysR substrate binding domain - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000002247 53.0
HKD2_k127_7794005_0 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 383.0
HKD2_k127_7794005_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 354.0
HKD2_k127_7794005_10 - - - - 0.0000006709 55.0
HKD2_k127_7794005_11 Cysteine rich repeat - - - 0.000002217 57.0
HKD2_k127_7794005_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 345.0
HKD2_k127_7794005_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 263.0
HKD2_k127_7794005_4 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000003651 201.0
HKD2_k127_7794005_5 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000000008171 149.0
HKD2_k127_7794005_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000001842 101.0
HKD2_k127_7794005_7 COG3000 Sterol desaturase - - - 0.00000000000000000007564 96.0
HKD2_k127_7794005_8 - - - - 0.000000000000000004277 95.0
HKD2_k127_7794005_9 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000001384 62.0
HKD2_k127_7808474_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 4.456e-206 648.0
HKD2_k127_7808474_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 442.0
HKD2_k127_7808474_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 419.0
HKD2_k127_7808474_3 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 418.0
HKD2_k127_7808474_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
HKD2_k127_7808474_5 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000006356 161.0
HKD2_k127_7808474_6 assembly protein K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000001377 103.0
HKD2_k127_7817714_0 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 458.0
HKD2_k127_7817714_1 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K00788,K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 2.5.1.3,3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 303.0
HKD2_k127_7817714_2 Tellurite resistance protein TerB K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000005394 243.0
HKD2_k127_7823688_0 Feruloyl esterase - - - 7.265e-202 640.0
HKD2_k127_7823688_1 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000321 226.0
HKD2_k127_7823688_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000001077 109.0
HKD2_k127_7832321_0 Acetolactate synthase K01652 - 2.2.1.6 0.0 1086.0
HKD2_k127_7832321_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.953e-285 884.0
HKD2_k127_7832321_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.275e-196 619.0
HKD2_k127_7832321_3 Rod shape-determining protein (MreB) K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 464.0
HKD2_k127_7832321_4 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 439.0
HKD2_k127_7832321_5 Acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 299.0
HKD2_k127_7832321_6 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000001127 189.0
HKD2_k127_7832321_8 cyclic nucleotide binding K01420 - - 0.00000000000000007621 83.0
HKD2_k127_7832321_9 PilZ domain - - - 0.00000000000001809 76.0
HKD2_k127_7918144_0 Flavin containing amine oxidoreductase - - - 2.135e-244 766.0
HKD2_k127_7918144_1 Signal transduction histidine kinase K07638 - 2.7.13.3 8.309e-224 704.0
HKD2_k127_7918144_2 Cyclic nucleotide-monophosphate binding domain K07001 - - 9.47e-208 664.0
HKD2_k127_7918144_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 521.0
HKD2_k127_7918144_4 Two component transcriptional regulator K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 360.0
HKD2_k127_7918144_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002454 228.0
HKD2_k127_7918144_6 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000000002299 171.0
HKD2_k127_7918144_7 transcriptional regulator - - - 0.00000000000000000000000000000000000000000006525 168.0
HKD2_k127_7918144_8 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000003884 139.0
HKD2_k127_7940188_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 360.0
HKD2_k127_7940188_1 COG0491 Zn-dependent hydrolases, including glyoxylases - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 323.0
HKD2_k127_7940188_2 Predicted small integral membrane protein (DUF2165) - - - 0.0000000000000000000000000000000000000000000000000002532 189.0
HKD2_k127_7940188_3 - - - - 0.00000000000000000000000000000000000000000000003227 178.0
HKD2_k127_7940188_4 - - - - 0.00000000000000000000000000000003097 131.0
HKD2_k127_796570_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 1.814e-210 659.0
HKD2_k127_796570_1 NYN domain - - - 2.289e-202 646.0
HKD2_k127_796570_10 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000002247 203.0
HKD2_k127_796570_11 - - - - 0.00000000000000000000000000000000003706 137.0
HKD2_k127_796570_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.838e-195 615.0
HKD2_k127_796570_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 531.0
HKD2_k127_796570_4 KR domain K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 403.0
HKD2_k127_796570_5 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 345.0
HKD2_k127_796570_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 334.0
HKD2_k127_796570_7 synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 299.0
HKD2_k127_796570_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HKD2_k127_796570_9 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 303.0
HKD2_k127_7967659_0 Histidine kinase K13587 - 2.7.13.3 5.989e-259 823.0
HKD2_k127_7967659_1 Glycosyl transferase family group 2 K03669 GO:0005575,GO:0016020 - 4.43e-248 782.0
HKD2_k127_7967659_10 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
HKD2_k127_7967659_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000000000004488 171.0
HKD2_k127_7967659_12 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000001868 148.0
HKD2_k127_7967659_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000358 134.0
HKD2_k127_7967659_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000003744 143.0
HKD2_k127_7967659_15 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000002471 91.0
HKD2_k127_7967659_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 2.979e-202 646.0
HKD2_k127_7967659_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 2.239e-199 625.0
HKD2_k127_7967659_4 YcjX-like family, DUF463 K06918 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 607.0
HKD2_k127_7967659_5 AAA ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 497.0
HKD2_k127_7967659_6 Domain of unknown function (DUF697) K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 348.0
HKD2_k127_7967659_7 Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 296.0
HKD2_k127_7967659_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001532 263.0
HKD2_k127_7967659_9 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003064 266.0
HKD2_k127_7988231_0 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 6.385e-233 737.0
HKD2_k127_7988231_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 527.0
HKD2_k127_7988231_2 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 465.0
HKD2_k127_7988231_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 351.0
HKD2_k127_7988231_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000168 256.0
HKD2_k127_7988231_5 AraC-binding-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008736 253.0
HKD2_k127_7988231_6 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
HKD2_k127_7988231_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000008723 173.0
HKD2_k127_7988231_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000001199 97.0
HKD2_k127_7988883_0 ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 594.0
HKD2_k127_7988883_1 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 485.0
HKD2_k127_7988883_2 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 428.0
HKD2_k127_7988883_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
HKD2_k127_7988883_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002095 269.0
HKD2_k127_7988883_5 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000001175 213.0
HKD2_k127_7988883_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000003066 204.0
HKD2_k127_7988883_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000414 176.0
HKD2_k127_7988883_8 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000003683 93.0
HKD2_k127_8054595_0 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 290.0
HKD2_k127_8054595_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000003754 175.0
HKD2_k127_8054595_2 Two component transcriptional regulator PhoB, winged helix family K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001001 82.0
HKD2_k127_8104288_0 Signal transduction histidine kinase K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 1.394e-288 905.0
HKD2_k127_8104288_1 Sigma-54 interaction domain K13599 - - 6.954e-262 812.0
HKD2_k127_8104288_2 Sigma-54 interaction domain K07712 - - 7.185e-256 796.0
HKD2_k127_8104288_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 591.0
HKD2_k127_8104288_4 PAS fold K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 533.0
HKD2_k127_8104288_5 branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 373.0
HKD2_k127_8104288_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000002068 156.0
HKD2_k127_8104288_7 EF-hand, calcium binding motif - - - 0.0000000000000000000001528 97.0
HKD2_k127_8124802_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.436e-249 777.0
HKD2_k127_8124802_1 MiaB-like tRNA modifying K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 6.079e-198 625.0
HKD2_k127_8124802_2 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 454.0
HKD2_k127_8124802_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 441.0
HKD2_k127_8124802_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 366.0
HKD2_k127_8124802_5 probably involved in intracellular septation K06190 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 298.0
HKD2_k127_8124802_6 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008061 262.0
HKD2_k127_8124802_7 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002223 189.0
HKD2_k127_8128507_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1341.0
HKD2_k127_8128507_1 cobalt chelatase K09883 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 442.0
HKD2_k127_8128507_10 Esterase-like activity of phytase - - - 0.00000000000003331 80.0
HKD2_k127_8128507_11 Haemolysin-type calcium binding protein related domain K01406 - 3.4.24.40 0.00000000000006073 80.0
HKD2_k127_8128507_2 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 355.0
HKD2_k127_8128507_3 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007659 276.0
HKD2_k127_8128507_4 Staphylococcal nuclease homologue - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002639 263.0
HKD2_k127_8128507_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000001965 221.0
HKD2_k127_8128507_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001662 159.0
HKD2_k127_8128507_7 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000005584 156.0
HKD2_k127_8128507_8 S4 domain K04762 - - 0.0000000000000000000000000000001123 136.0
HKD2_k127_8138778_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 8.146e-311 961.0
HKD2_k127_8138778_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 353.0
HKD2_k127_8138778_2 cell septum assembly - - - 0.0000000000000000000000000000000000000003754 164.0
HKD2_k127_814912_0 Dehydrogenase K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 9.835e-198 625.0
HKD2_k127_814912_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 381.0
HKD2_k127_8160873_0 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 2.273e-290 902.0
HKD2_k127_8160873_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.49e-284 880.0
HKD2_k127_8160873_10 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003642 269.0
HKD2_k127_8160873_12 Acetyltransferase (GNAT) domain K03830 - - 0.00013 51.0
HKD2_k127_8160873_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 3.74e-222 699.0
HKD2_k127_8160873_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.819e-211 664.0
HKD2_k127_8160873_4 amino acid peptide transporter K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 577.0
HKD2_k127_8160873_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 542.0
HKD2_k127_8160873_6 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 446.0
HKD2_k127_8160873_7 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 436.0
HKD2_k127_8160873_8 Protein of unknown function (DUF2865) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 364.0
HKD2_k127_8160873_9 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 293.0
HKD2_k127_8168434_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1173.0
HKD2_k127_8168434_1 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 398.0
HKD2_k127_8168434_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000002128 135.0
HKD2_k127_8168434_11 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000003701 117.0
HKD2_k127_8168434_12 - - - - 0.000000000000000000000000003245 114.0
HKD2_k127_8168434_13 - - - - 0.0000000000000000000000000583 121.0
HKD2_k127_8168434_14 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000008248 75.0
HKD2_k127_8168434_16 - - - - 0.00000008543 63.0
HKD2_k127_8168434_17 SnoaL-like domain K06893 - - 0.000001509 59.0
HKD2_k127_8168434_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 361.0
HKD2_k127_8168434_3 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004194 261.0
HKD2_k127_8168434_4 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000000000000001414 226.0
HKD2_k127_8168434_5 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000002682 220.0
HKD2_k127_8168434_6 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000001901 197.0
HKD2_k127_8168434_7 Flavodoxin - - - 0.000000000000000000000000000000000000000000000002361 178.0
HKD2_k127_8179412_0 DinB superfamily - - - 3.126e-216 678.0
HKD2_k127_8179412_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 2.963e-196 621.0
HKD2_k127_8179412_11 Protein of unknown function (DUF1326) - - - 0.000000000001725 71.0
HKD2_k127_8179412_12 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000008338 58.0
HKD2_k127_8179412_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 518.0
HKD2_k127_8179412_3 Patatin phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 514.0
HKD2_k127_8179412_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 483.0
HKD2_k127_8179412_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003889 252.0
HKD2_k127_8179412_6 Terminase RNaseH-like domain - - - 0.0000000000000000000000000000000000000000000000004725 179.0
HKD2_k127_8179412_7 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000003018 136.0
HKD2_k127_8179412_8 Terminase small subunit - - - 0.0000000000000000000000002984 111.0
HKD2_k127_8179412_9 Protein of unknown function (DUF1326) - - - 0.000000000000000000000009406 106.0
HKD2_k127_8203902_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
HKD2_k127_8203902_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 362.0
HKD2_k127_8203902_2 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 337.0
HKD2_k127_8203902_3 Glycosyl transferase family group 2 - - - 0.00000000000000000000000003273 121.0
HKD2_k127_8219486_0 ABC transporter transmembrane region K02021,K06147,K11085 - - 2.96e-240 759.0
HKD2_k127_8219486_1 glutamate--cysteine ligase K01919 - 6.3.2.2 7.751e-231 721.0
HKD2_k127_8219486_10 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 469.0
HKD2_k127_8219486_11 Lipopolysaccharide-assembly, LptC-related K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 474.0
HKD2_k127_8219486_12 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 429.0
HKD2_k127_8219486_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 389.0
HKD2_k127_8219486_14 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 392.0
HKD2_k127_8219486_15 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 383.0
HKD2_k127_8219486_16 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 364.0
HKD2_k127_8219486_17 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 350.0
HKD2_k127_8219486_18 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 344.0
HKD2_k127_8219486_19 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 342.0
HKD2_k127_8219486_2 Domain of unknown function (DUF374) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 9.043e-231 733.0
HKD2_k127_8219486_20 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 330.0
HKD2_k127_8219486_21 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 323.0
HKD2_k127_8219486_22 glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 317.0
HKD2_k127_8219486_23 Protein tyrosine serine phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 298.0
HKD2_k127_8219486_24 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 271.0
HKD2_k127_8219486_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
HKD2_k127_8219486_26 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.000000000000000000000000000000000000000000000000000002756 196.0
HKD2_k127_8219486_27 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan K01233 GO:0003674,GO:0003824,GO:0004553,GO:0016787,GO:0016798,GO:0016977 3.2.1.132 0.00000000000000000000000000000000000000000005099 171.0
HKD2_k127_8219486_28 LUD domain K00782 - - 0.0000000000000000000000000000000000000000014 169.0
HKD2_k127_8219486_29 Cytochrome c2 K08738 - - 0.000000000000000000000000000000001029 135.0
HKD2_k127_8219486_3 FAD linked oxidases, C-terminal domain K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 2.523e-225 707.0
HKD2_k127_8219486_30 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.0000000000000000000000000000004831 124.0
HKD2_k127_8219486_31 Domain of unknown function (DUF4170) - - - 0.00000000000000000000000000003661 120.0
HKD2_k127_8219486_32 PFAM Cytochrome C - - - 0.0000000000000001098 82.0
HKD2_k127_8219486_33 PspC domain protein - - - 0.00000000000002105 76.0
HKD2_k127_8219486_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.081e-216 683.0
HKD2_k127_8219486_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 1.214e-206 654.0
HKD2_k127_8219486_6 Belongs to the GARS family K01945 - 6.3.4.13 4.813e-205 646.0
HKD2_k127_8219486_7 Cysteine-rich domain K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 3.431e-203 640.0
HKD2_k127_8219486_8 Domain of unknown function (DUF3390) K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 586.0
HKD2_k127_8219486_9 FAD linked oxidase K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 531.0
HKD2_k127_8281205_0 amine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000003588 250.0
HKD2_k127_8281205_1 - - - - 0.00000000000000008204 83.0
HKD2_k127_8281205_2 Dienelactone hydrolase - - - 0.0000000001518 70.0
HKD2_k127_8285984_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006561 240.0
HKD2_k127_8285984_1 Phasin protein - - - 0.0000000000000000000006401 101.0
HKD2_k127_829083_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.195e-242 754.0
HKD2_k127_829083_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.733e-236 732.0
HKD2_k127_829083_10 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 331.0
HKD2_k127_829083_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 322.0
HKD2_k127_829083_12 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 303.0
HKD2_k127_829083_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 291.0
HKD2_k127_829083_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 293.0
HKD2_k127_829083_15 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
HKD2_k127_829083_16 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003814 247.0
HKD2_k127_829083_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000228 239.0
HKD2_k127_829083_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000116 237.0
HKD2_k127_829083_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000005991 235.0
HKD2_k127_829083_2 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 1.109e-220 690.0
HKD2_k127_829083_20 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000007943 233.0
HKD2_k127_829083_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001776 218.0
HKD2_k127_829083_22 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003564 203.0
HKD2_k127_829083_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000377 198.0
HKD2_k127_829083_24 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000002216 191.0
HKD2_k127_829083_25 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001482 186.0
HKD2_k127_829083_26 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000003183 179.0
HKD2_k127_829083_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006952 172.0
HKD2_k127_829083_28 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000007343 171.0
HKD2_k127_829083_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000001894 132.0
HKD2_k127_829083_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.264e-205 640.0
HKD2_k127_829083_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009201 131.0
HKD2_k127_829083_31 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000003016 86.0
HKD2_k127_829083_32 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000005552 83.0
HKD2_k127_829083_4 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 5.414e-194 616.0
HKD2_k127_829083_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 492.0
HKD2_k127_829083_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 402.0
HKD2_k127_829083_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
HKD2_k127_829083_8 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 365.0
HKD2_k127_829083_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 332.0
HKD2_k127_8329215_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 7.583e-271 841.0
HKD2_k127_8329215_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.042e-219 686.0
HKD2_k127_8329215_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 571.0
HKD2_k127_8329215_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 401.0
HKD2_k127_8329215_4 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000000000000005196 182.0
HKD2_k127_8329215_5 Short-chain dehydrogenase reductase SDR - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00008226 45.0
HKD2_k127_8383118_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.561e-229 717.0
HKD2_k127_8383118_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 411.0
HKD2_k127_8383118_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 344.0
HKD2_k127_8383118_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
HKD2_k127_8383118_4 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005852 278.0
HKD2_k127_8383118_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000002166 178.0
HKD2_k127_8383118_6 cell cycle - - - 0.0000000000000000000000000000001717 126.0
HKD2_k127_8387284_0 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003574 266.0
HKD2_k127_8387284_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000007814 245.0
HKD2_k127_8387284_2 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000000000001492 219.0
HKD2_k127_8425968_0 Participates in both transcription termination and antitermination K02600 - - 3.366e-267 831.0
HKD2_k127_8425968_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.508e-224 702.0
HKD2_k127_8425968_10 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000000461 215.0
HKD2_k127_8425968_11 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000005264 205.0
HKD2_k127_8425968_12 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000003172 192.0
HKD2_k127_8425968_13 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000001026 180.0
HKD2_k127_8425968_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000002696 158.0
HKD2_k127_8425968_15 - - - - 0.000008248 57.0
HKD2_k127_8425968_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.67e-196 624.0
HKD2_k127_8425968_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 602.0
HKD2_k127_8425968_4 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 534.0
HKD2_k127_8425968_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 414.0
HKD2_k127_8425968_6 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 392.0
HKD2_k127_8425968_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 285.0
HKD2_k127_8425968_8 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005169 258.0
HKD2_k127_8425968_9 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000009752 214.0
HKD2_k127_8526463_0 ABC transporter K06147,K18893 - - 6.902e-246 773.0
HKD2_k127_8526463_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00410,K00412 - - 7.144e-227 708.0
HKD2_k127_8526463_10 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000001034 139.0
HKD2_k127_8526463_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K12980,K16079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008653,GO:0009279,GO:0009311,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0042802,GO:0042803,GO:0043170,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044425,GO:0044462,GO:0044464,GO:0046493,GO:0046983,GO:0050528,GO:0052689,GO:0071704,GO:0071944,GO:1901135,GO:1901269,GO:1903509 - 0.0000000000000000000000001164 115.0
HKD2_k127_8526463_12 - - - - 0.0000000000000000001915 100.0
HKD2_k127_8526463_2 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 563.0
HKD2_k127_8526463_3 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 516.0
HKD2_k127_8526463_4 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 454.0
HKD2_k127_8526463_5 cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 364.0
HKD2_k127_8526463_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 369.0
HKD2_k127_8526463_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 297.0
HKD2_k127_8526463_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001301 239.0
HKD2_k127_8526463_9 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008048 231.0
HKD2_k127_8556084_0 MMPL family K07003 - - 0.0 1087.0
HKD2_k127_8556084_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K15778 - 5.4.2.2,5.4.2.8 4.814e-286 882.0
HKD2_k127_8556084_10 glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 292.0
HKD2_k127_8556084_11 helix_turn_helix ASNC type K05800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001375 277.0
HKD2_k127_8556084_12 Chase2 domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005322 284.0
HKD2_k127_8556084_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003308 276.0
HKD2_k127_8556084_14 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 261.0
HKD2_k127_8556084_15 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000172 254.0
HKD2_k127_8556084_16 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000000000004267 233.0
HKD2_k127_8556084_17 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
HKD2_k127_8556084_18 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000000000000000000000002287 149.0
HKD2_k127_8556084_19 Belongs to the 'phage' integrase family - - - 0.0000000000000000000003111 101.0
HKD2_k127_8556084_2 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.386e-211 667.0
HKD2_k127_8556084_21 - - - - 0.000000000000000002118 98.0
HKD2_k127_8556084_22 Protein of unknown function (DUF1289) K06938 - - 0.000000000000004443 81.0
HKD2_k127_8556084_23 Helix-turn-helix domain - - - 0.000006211 52.0
HKD2_k127_8556084_3 Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 581.0
HKD2_k127_8556084_4 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 554.0
HKD2_k127_8556084_5 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 452.0
HKD2_k127_8556084_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 411.0
HKD2_k127_8556084_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 377.0
HKD2_k127_8556084_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 324.0
HKD2_k127_8556084_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
HKD2_k127_8700305_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.907e-221 691.0
HKD2_k127_8700305_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 473.0
HKD2_k127_8700305_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 304.0
HKD2_k127_8700305_3 Rhomboid family - - - 0.00000000000000000000000000000000000001498 150.0
HKD2_k127_8731240_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 479.0
HKD2_k127_8731240_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000005482 246.0
HKD2_k127_885396_0 rrna methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
HKD2_k127_885396_1 Alcohol dehydrogenase zinc-binding K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 264.0
HKD2_k127_885396_2 invasion associated locus B - - - 0.00000000000000000000000000000000000000000004412 168.0
HKD2_k127_885396_3 Smr domain - - - 0.0000000000000000000000000000000000000002068 152.0
HKD2_k127_8957184_0 Transcriptional regulatory protein, C terminal - - - 0.0 1302.0
HKD2_k127_8957184_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 505.0
HKD2_k127_8957184_2 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 479.0
HKD2_k127_8957184_3 Bacterial dnaA protein - - - 0.0000000000000821 74.0
HKD2_k127_8962977_0 AcrB/AcrD/AcrF family K03296,K18902 - - 0.0 1182.0
HKD2_k127_8962977_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
HKD2_k127_8962977_2 DoxX family K15977 - - 0.0000000000000000000000000000000000000000000000000985 180.0
HKD2_k127_8962977_3 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000005692 135.0
HKD2_k127_8962977_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000001703 118.0
HKD2_k127_8962977_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298 - - 0.00000000000000000000003491 108.0
HKD2_k127_9004484_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 4.986e-278 865.0
HKD2_k127_9004484_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 9.572e-274 852.0
HKD2_k127_9004484_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 569.0
HKD2_k127_9004484_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 306.0
HKD2_k127_9004484_4 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
HKD2_k127_9004484_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000007764 167.0
HKD2_k127_9014275_0 Carbamoyl-phosphate synthase L chain ATP-binding K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0 1122.0
HKD2_k127_9014275_1 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 7.82e-304 935.0
HKD2_k127_9014275_10 - - - - 0.0000000000000000000000000001473 119.0
HKD2_k127_9014275_11 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000001392 102.0
HKD2_k127_9014275_13 Domain of unknown function (DUF4189) - - - 0.000000000000000000001563 106.0
HKD2_k127_9014275_14 periplasmic protein - - - 0.000000000000000000003083 107.0
HKD2_k127_9014275_15 YARHG - - - 0.0000000000004087 75.0
HKD2_k127_9014275_17 Phage integrase family - - - 0.000001297 57.0
HKD2_k127_9014275_18 - - - - 0.00001857 47.0
HKD2_k127_9014275_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 445.0
HKD2_k127_9014275_3 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 411.0
HKD2_k127_9014275_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 365.0
HKD2_k127_9014275_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 344.0
HKD2_k127_9014275_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 291.0
HKD2_k127_9014275_7 ATP12 chaperone protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009575 261.0
HKD2_k127_9014275_8 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000006812 259.0
HKD2_k127_9014275_9 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000001069 179.0
HKD2_k127_9025519_0 Beta-eliminating lyase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 558.0
HKD2_k127_9025519_1 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 423.0
HKD2_k127_9025519_2 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 381.0
HKD2_k127_9025519_3 assembly protein K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000005156 148.0
HKD2_k127_9025714_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 533.0
HKD2_k127_9025714_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 528.0
HKD2_k127_9025714_3 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 412.0
HKD2_k127_9025714_4 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 401.0
HKD2_k127_9025714_5 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 353.0
HKD2_k127_9025714_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001215 258.0
HKD2_k127_9079963_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1225.0
HKD2_k127_9079963_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.874e-302 941.0
HKD2_k127_9079963_10 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 490.0
HKD2_k127_9079963_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009234 423.0
HKD2_k127_9079963_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 371.0
HKD2_k127_9079963_13 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 331.0
HKD2_k127_9079963_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
HKD2_k127_9079963_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000003283 263.0
HKD2_k127_9079963_16 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000006221 244.0
HKD2_k127_9079963_17 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000005702 194.0
HKD2_k127_9079963_18 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000564 175.0
HKD2_k127_9079963_19 Ribbon-helix-helix domain - - - 0.000000000000000000002475 95.0
HKD2_k127_9079963_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 9.426e-266 823.0
HKD2_k127_9079963_20 Domain of unknown function (DUF4169) - - - 0.00006664 48.0
HKD2_k127_9079963_3 AsmA family K07289 - - 3.353e-259 849.0
HKD2_k127_9079963_4 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 2.023e-251 788.0
HKD2_k127_9079963_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.174e-237 743.0
HKD2_k127_9079963_6 Protein of unknown function (DUF3754) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 604.0
HKD2_k127_9079963_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 603.0
HKD2_k127_9079963_8 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
HKD2_k127_9079963_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 494.0
HKD2_k127_9099416_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.277e-264 825.0
HKD2_k127_9099416_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 527.0
HKD2_k127_9099416_2 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 432.0
HKD2_k127_9099416_3 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000204 242.0
HKD2_k127_9099416_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000002378 66.0
HKD2_k127_9118727_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0 1254.0
HKD2_k127_9118727_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1212.0
HKD2_k127_9118727_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 397.0
HKD2_k127_9118727_11 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 398.0
HKD2_k127_9118727_12 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 347.0
HKD2_k127_9118727_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
HKD2_k127_9118727_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000002442 240.0
HKD2_k127_9118727_15 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000004336 183.0
HKD2_k127_9118727_16 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000001262 167.0
HKD2_k127_9118727_17 Pfam:DUF1049 - - - 0.00000000000000000000000000000000000000009575 153.0
HKD2_k127_9118727_18 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000000000000000000006445 153.0
HKD2_k127_9118727_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1e-323 996.0
HKD2_k127_9118727_3 Histidine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.602e-308 967.0
HKD2_k127_9118727_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 6.832e-258 798.0
HKD2_k127_9118727_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.439e-241 749.0
HKD2_k127_9118727_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 1.177e-204 645.0
HKD2_k127_9118727_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 9.312e-197 626.0
HKD2_k127_9118727_8 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 572.0
HKD2_k127_9118727_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
HKD2_k127_9164099_0 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 545.0
HKD2_k127_9164099_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 411.0
HKD2_k127_9164099_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000108 86.0
HKD2_k127_9174753_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 6.999e-225 702.0
HKD2_k127_9174753_1 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 486.0
HKD2_k127_9174753_10 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001101 216.0
HKD2_k127_9174753_11 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000002531 181.0
HKD2_k127_9174753_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000731 153.0
HKD2_k127_9174753_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005838 143.0
HKD2_k127_9174753_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 466.0
HKD2_k127_9174753_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 423.0
HKD2_k127_9174753_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
HKD2_k127_9174753_5 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
HKD2_k127_9174753_6 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 323.0
HKD2_k127_9174753_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 307.0
HKD2_k127_9174753_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
HKD2_k127_9174753_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
HKD2_k127_9180955_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 9.438e-284 883.0
HKD2_k127_9180955_1 Pantothenic acid kinase K00867 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 488.0
HKD2_k127_9180955_2 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 387.0
HKD2_k127_9180955_3 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 340.0
HKD2_k127_9180955_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000004537 267.0
HKD2_k127_9180955_5 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000001252 126.0
HKD2_k127_9180955_6 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000002018 85.0
HKD2_k127_9201524_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 519.0
HKD2_k127_9201524_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 497.0
HKD2_k127_9201524_2 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 327.0
HKD2_k127_9201524_3 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 299.0
HKD2_k127_9201524_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009713 234.0
HKD2_k127_9201524_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001047 126.0
HKD2_k127_9201524_6 Protein of unknown function (DUF465) - - - 0.0000000000000000000005214 96.0
HKD2_k127_9201524_7 Small protein - - - 0.0000000000000000004187 88.0
HKD2_k127_9211572_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.044e-277 874.0
HKD2_k127_9211572_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.011e-215 675.0
HKD2_k127_9211572_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 455.0
HKD2_k127_9211572_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000008576 214.0
HKD2_k127_9211572_4 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000000000000001172 157.0
HKD2_k127_9211572_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000006263 141.0
HKD2_k127_9418022_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 590.0
HKD2_k127_9418022_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
HKD2_k127_9418022_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
HKD2_k127_9418022_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 303.0
HKD2_k127_9418022_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000281 96.0
HKD2_k127_9418022_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002549 78.0
HKD2_k127_9522705_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.42e-198 620.0
HKD2_k127_9522705_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 397.0
HKD2_k127_9522705_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
HKD2_k127_9522705_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 304.0
HKD2_k127_9522705_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000009459 244.0
HKD2_k127_9522705_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004416 225.0
HKD2_k127_9522705_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000004385 201.0
HKD2_k127_9522705_7 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000003141 178.0
HKD2_k127_9522705_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000385 102.0
HKD2_k127_9542471_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 444.0
HKD2_k127_9542471_1 Alpha beta hydrolase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 337.0
HKD2_k127_9542471_2 SPTR NmrA family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
HKD2_k127_9543490_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
HKD2_k127_9543490_1 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
HKD2_k127_9543490_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000001196 124.0
HKD2_k127_9543490_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0001727 45.0
HKD2_k127_9557683_0 Phosphopantetheine attachment site K00666 - - 0.0 1103.0
HKD2_k127_9557683_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 595.0
HKD2_k127_9557683_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 573.0
HKD2_k127_9557683_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 403.0
HKD2_k127_9557683_4 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000002812 162.0
HKD2_k127_9557683_5 THUMP - - - 0.00000000000000000000000000000000003412 139.0
HKD2_k127_9557683_6 GYD domain - - - 0.00000000000000000000000000000005729 126.0
HKD2_k127_9557683_7 - - - - 0.000000000000000000948 88.0
HKD2_k127_9603887_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 561.0
HKD2_k127_9603887_1 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004142 262.0
HKD2_k127_9665347_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2090.0
HKD2_k127_9869546_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.47e-214 667.0
HKD2_k127_9869546_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 475.0