Overview

ID MAG01817
Name HKD2_bin.73
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota_A
Class Ignavibacteria
Order SJA-28
Family B-1AR
Genus
Species
Assembly information
Completeness (%) 75.59
Contamination (%) 2.19
GC content (%) 41.0
N50 (bp) 7,442
Genome size (bp) 2,088,669

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1840

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10026430_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 608.0
HKD2_k127_10041226_0 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 2.615e-197 622.0
HKD2_k127_10041226_1 glycogen (starch) synthase activity K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 493.0
HKD2_k127_10041226_10 Belongs to the peptidase S8 family - - - 0.00000000000000000008351 90.0
HKD2_k127_10041226_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 355.0
HKD2_k127_10041226_3 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 353.0
HKD2_k127_10041226_4 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
HKD2_k127_10041226_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000004651 245.0
HKD2_k127_10041226_6 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000005536 179.0
HKD2_k127_10041226_7 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000003969 186.0
HKD2_k127_10041226_8 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000002672 154.0
HKD2_k127_10107537_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 325.0
HKD2_k127_10107537_1 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370,K15582,K19228 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 310.0
HKD2_k127_10107537_2 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000003422 237.0
HKD2_k127_10107537_3 metal cluster binding - - - 0.000000000000000000000000000000000000000007811 160.0
HKD2_k127_10107537_4 cysteine-type peptidase activity K13694,K13695 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.4.17.13 0.0000000000000000000000000002946 122.0
HKD2_k127_10107537_5 CoA-transferase family III - - - 0.0000000000000000000000000005813 115.0
HKD2_k127_10107537_6 RNA polymerase, sigma-54 factor K03092 - - 0.0000001558 56.0
HKD2_k127_10118638_0 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 534.0
HKD2_k127_10118638_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 310.0
HKD2_k127_10118638_10 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000005543 54.0
HKD2_k127_10118638_11 Carboxypeptidase regulatory-like domain - - - 0.0003055 52.0
HKD2_k127_10118638_2 PFAM metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 293.0
HKD2_k127_10118638_3 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006254 285.0
HKD2_k127_10118638_4 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008411 248.0
HKD2_k127_10118638_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000003528 198.0
HKD2_k127_10118638_6 rRNA (guanine-N2-)-methyltransferase activity K08316,K15257 - 2.1.1.171 0.000000000000000000000000001222 120.0
HKD2_k127_10118638_7 Protein of unknown function (DUF1232) - - - 0.000000000000000000004336 97.0
HKD2_k127_10118638_8 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000003526 79.0
HKD2_k127_10118638_9 Protein of unknown function, DUF255 - - - 0.0000000001658 68.0
HKD2_k127_10127442_0 Photosynthesis system II assembly factor YCF48 - - - 0.0000000001199 73.0
HKD2_k127_10162637_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 430.0
HKD2_k127_10162637_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000001578 58.0
HKD2_k127_107354_0 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 445.0
HKD2_k127_107354_1 chain release factor K15034 - - 0.00000000000000000000002799 104.0
HKD2_k127_107354_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000005722 106.0
HKD2_k127_107354_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000007999 76.0
HKD2_k127_107354_4 - K07164,K22391 - 3.5.4.16 0.00000002535 62.0
HKD2_k127_1179809_0 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 2.179e-194 625.0
HKD2_k127_1179809_1 Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 478.0
HKD2_k127_1179809_2 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
HKD2_k127_1179809_3 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000003518 207.0
HKD2_k127_1193658_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.763e-204 651.0
HKD2_k127_1193658_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 620.0
HKD2_k127_1193658_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 484.0
HKD2_k127_1193658_3 phosphorelay signal transduction system - - - 0.0000000000000003506 83.0
HKD2_k127_1193658_4 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.0000000000000004533 79.0
HKD2_k127_1193658_5 Histidine kinase K11527 - 2.7.13.3 0.000001012 55.0
HKD2_k127_1233357_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 463.0
HKD2_k127_1233357_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 300.0
HKD2_k127_1233357_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000002938 207.0
HKD2_k127_1242229_0 lipopolysaccharide-transporting ATPase activity K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 340.0
HKD2_k127_1242229_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 288.0
HKD2_k127_1242229_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000005457 169.0
HKD2_k127_1242229_3 - - - - 0.0000000000000000000000000000000000001738 148.0
HKD2_k127_1242229_4 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000000000000000007749 124.0
HKD2_k127_1293217_0 acyl-CoA dehydrogenase activity K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 500.0
HKD2_k127_1293217_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K00558,K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 394.0
HKD2_k127_1293217_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 366.0
HKD2_k127_1293217_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 330.0
HKD2_k127_1293217_4 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000527 160.0
HKD2_k127_1293217_5 - - - - 0.00000000000000000000000000007953 121.0
HKD2_k127_1293217_6 CoA-binding protein K06929 - - 0.0000000000000000000000003078 110.0
HKD2_k127_1293217_7 - - - - 0.00000000000000001715 84.0
HKD2_k127_1293217_8 - - - - 0.000004706 51.0
HKD2_k127_130362_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 297.0
HKD2_k127_130362_1 pseudouridine synthase activity K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000002493 246.0
HKD2_k127_130362_2 - - - - 0.000000000000000000000000346 110.0
HKD2_k127_130362_3 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000005208 111.0
HKD2_k127_130362_4 methyltransferase activity - - - 0.0000000000000000393 87.0
HKD2_k127_130362_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000009336 58.0
HKD2_k127_1342187_0 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 4.072e-228 730.0
HKD2_k127_1342187_1 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 568.0
HKD2_k127_1342187_2 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 524.0
HKD2_k127_1342187_3 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
HKD2_k127_1342187_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
HKD2_k127_1342187_5 unfolded protein binding K06142 - - 0.00000000000000000000000000000000000005544 149.0
HKD2_k127_1342187_6 unfolded protein binding K06142 - - 0.0000000000000004942 85.0
HKD2_k127_1342187_7 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000001867 51.0
HKD2_k127_1342187_8 guanyl-nucleotide exchange factor activity - - - 0.00006179 45.0
HKD2_k127_1346632_0 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 1.691e-220 717.0
HKD2_k127_1346632_1 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 302.0
HKD2_k127_1346632_2 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.0001454 55.0
HKD2_k127_14210_0 peptidase activity, acting on L-amino acid peptides K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 590.0
HKD2_k127_14210_1 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 294.0
HKD2_k127_14210_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000005247 248.0
HKD2_k127_14210_3 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000002469 244.0
HKD2_k127_14210_4 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005153 218.0
HKD2_k127_1422910_0 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 565.0
HKD2_k127_1422910_1 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 479.0
HKD2_k127_1422910_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000165 275.0
HKD2_k127_1422910_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000001848 121.0
HKD2_k127_1422910_4 nitrite reductase [NAD(P)H] activity K05710,K15762,K22360 - - 0.00000000000000000009109 93.0
HKD2_k127_1470170_0 membrane organization K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 596.0
HKD2_k127_1470170_1 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000003287 98.0
HKD2_k127_1484603_0 ATPase activity K01990,K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000008802 191.0
HKD2_k127_1484603_1 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.00000000000000000000000000000000000000000000000001338 184.0
HKD2_k127_1484603_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000005795 194.0
HKD2_k127_1484603_3 cell envelope organization K05807,K08309 - - 0.00000000000000000000000000000000000000000001951 170.0
HKD2_k127_1484603_4 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000000000056 175.0
HKD2_k127_1484603_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000004552 147.0
HKD2_k127_1484603_6 Histidine kinase K07675 - 2.7.13.3 0.0000000000001566 77.0
HKD2_k127_1484603_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000002791 74.0
HKD2_k127_1484603_8 Domain of unknown function (DUF4365) - - - 0.0008098 52.0
HKD2_k127_1484817_0 Peptidase C1-like family K01372 - 3.4.22.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001842 272.0
HKD2_k127_1484817_1 Pas domain s-box - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002362 285.0
HKD2_k127_1484817_2 response regulator K02282,K07689 - - 0.000000000000000000000000000005737 121.0
HKD2_k127_1491758_0 Glycosyl transferases group 1 - - - 1.017e-282 890.0
HKD2_k127_1491758_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007474 241.0
HKD2_k127_1491758_2 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
HKD2_k127_1498456_0 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 568.0
HKD2_k127_1498456_1 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 403.0
HKD2_k127_1498456_2 transcription antitermination K03625 - - 0.0000000000000000000000000000000001958 137.0
HKD2_k127_1498456_3 Gram-negative-bacterium-type cell wall biogenesis - - - 0.00000000000000000000000000001196 129.0
HKD2_k127_1545880_0 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 473.0
HKD2_k127_1548341_0 4 iron, 4 sulfur cluster binding K00184 - - 0.0 1145.0
HKD2_k127_1548341_1 Polysulphide reductase, NrfD K00185 - - 2.112e-241 751.0
HKD2_k127_1548341_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 476.0
HKD2_k127_1548341_3 zinc ion transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 468.0
HKD2_k127_1548341_4 Cytochrome c K07243 - - 0.0000000000000000000000000000000000000000000001169 180.0
HKD2_k127_159511_0 Isocitrate/isopropylmalate dehydrogenase - - - 1.666e-211 667.0
HKD2_k127_159511_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 433.0
HKD2_k127_159511_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000007027 210.0
HKD2_k127_159511_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000005488 84.0
HKD2_k127_159511_4 protein histidine kinase activity K11959 - - 0.0003525 44.0
HKD2_k127_1599810_0 HMGL-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 527.0
HKD2_k127_1599810_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 485.0
HKD2_k127_1599810_2 PFAM Coenzyme A transferase K01027,K01028,K01031,K01034 - 2.8.3.5,2.8.3.6,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 367.0
HKD2_k127_1599810_3 PFAM Coenzyme A transferase K01029,K01032 - 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 356.0
HKD2_k127_1599810_4 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000004715 126.0
HKD2_k127_1602464_0 TonB-dependent receptor - - - 8.788e-236 756.0
HKD2_k127_1602464_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 475.0
HKD2_k127_1602464_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 379.0
HKD2_k127_1602464_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 356.0
HKD2_k127_1602464_4 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 302.0
HKD2_k127_1602464_5 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000002054 182.0
HKD2_k127_1602464_6 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000001194 172.0
HKD2_k127_1602464_7 Polymer-forming cytoskeletal - - - 0.000000000000000000002928 98.0
HKD2_k127_1602464_8 Functions in MreBCD complex in some organisms K03569 - - 0.00000000000000001964 82.0
HKD2_k127_1602464_9 Rhodanese Homology Domain K06917 - - 0.00000000000006029 77.0
HKD2_k127_1658368_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 406.0
HKD2_k127_1658368_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000002547 188.0
HKD2_k127_1673468_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 531.0
HKD2_k127_1673468_1 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000002615 161.0
HKD2_k127_1673468_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000002527 58.0
HKD2_k127_1711186_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 447.0
HKD2_k127_1711186_1 citrate synthase K01647 GO:0003674,GO:0003824,GO:0004108,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006082,GO:0006084,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0014823,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046483,GO:0046912,GO:0050896,GO:0051186,GO:0055086,GO:0055114,GO:0070013,GO:0071704,GO:0072350,GO:0072521,GO:1901135,GO:1901360,GO:1901564 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 400.0
HKD2_k127_1711186_2 plasmid maintenance K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 294.0
HKD2_k127_1711186_3 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000914 280.0
HKD2_k127_1711186_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000006065 243.0
HKD2_k127_1711186_5 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000004294 161.0
HKD2_k127_1711186_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001007 151.0
HKD2_k127_17498_0 COGs COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 408.0
HKD2_k127_17498_1 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009146 246.0
HKD2_k127_17498_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000005311 191.0
HKD2_k127_17498_3 Exodeoxyribonuclease III - - - 0.00000000000000008416 94.0
HKD2_k127_17498_4 Domain of unknown function (DUF4082) - - - 0.00000000006374 75.0
HKD2_k127_1819603_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 347.0
HKD2_k127_1819603_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 342.0
HKD2_k127_1819603_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
HKD2_k127_1819603_3 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.00000000000000000002596 104.0
HKD2_k127_1851250_0 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 8.924e-204 642.0
HKD2_k127_1851250_1 rRNA binding K02986 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 302.0
HKD2_k127_1851250_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001856 73.0
HKD2_k127_1851250_11 Outer membrane protein beta-barrel domain - - - 0.00000133 59.0
HKD2_k127_1851250_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
HKD2_k127_1851250_3 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001225 239.0
HKD2_k127_1851250_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002657 213.0
HKD2_k127_1851250_5 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000000102 172.0
HKD2_k127_1851250_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000392 163.0
HKD2_k127_1851250_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000002928 132.0
HKD2_k127_1851250_8 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000006234 81.0
HKD2_k127_1851250_9 RNA polymerase activity K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000005216 78.0
HKD2_k127_1858480_0 cellulose binding - - - 0.0000000000000000000000000004672 119.0
HKD2_k127_1865388_0 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 408.0
HKD2_k127_1865388_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001042 232.0
HKD2_k127_1865388_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000001763 204.0
HKD2_k127_1865388_3 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000000000000000000004606 138.0
HKD2_k127_1865388_4 cellulose binding - - - 0.00000000000000000000000008047 109.0
HKD2_k127_1865388_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000009432 120.0
HKD2_k127_1865388_6 Tetratricopeptide repeat - - - 0.0000000000000005136 89.0
HKD2_k127_1865388_7 Amidohydrolase K07045 - - 0.000000000001193 77.0
HKD2_k127_1865388_8 Polysaccharide biosynthesis protein - - - 0.00000002085 59.0
HKD2_k127_1925811_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 9.84e-276 859.0
HKD2_k127_1925811_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 437.0
HKD2_k127_1925811_2 membrane organization K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 361.0
HKD2_k127_1925811_3 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 336.0
HKD2_k127_1925811_4 single-stranded DNA binding K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000002679 226.0
HKD2_k127_1925811_5 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000005906 142.0
HKD2_k127_1925811_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000008068 69.0
HKD2_k127_1949536_0 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 456.0
HKD2_k127_1949536_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 407.0
HKD2_k127_1949536_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000004396 218.0
HKD2_k127_1949536_3 - - - - 0.0000000000000000000000000000000000000000007749 178.0
HKD2_k127_1949536_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000005583 89.0
HKD2_k127_1962026_0 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 545.0
HKD2_k127_1962026_1 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 411.0
HKD2_k127_1962026_2 Ferredoxin - - - 0.00000000000000000000000000000000000008765 145.0
HKD2_k127_1966128_0 response to heat K03696 - - 0.0 1137.0
HKD2_k127_1966128_1 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 442.0
HKD2_k127_1966128_2 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000006991 208.0
HKD2_k127_1966128_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000003713 186.0
HKD2_k127_1966128_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000002644 164.0
HKD2_k127_1966128_5 - - - - 0.00000000000000000000000000000000000000003251 163.0
HKD2_k127_1966128_6 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000002115 136.0
HKD2_k127_1966128_7 - - - - 0.00000000000000000000000000009614 124.0
HKD2_k127_1966128_8 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000001475 121.0
HKD2_k127_1966128_9 cellulose binding - - - 0.000000000000000016 82.0
HKD2_k127_199950_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079,K21572 - - 0.00000000000000000000000000000000000000000008922 169.0
HKD2_k127_199950_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079,K21572 - - 0.0000000000000000000002925 103.0
HKD2_k127_199950_2 Tricorn protease homolog - - - 0.0005654 52.0
HKD2_k127_2009211_0 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 2.585e-240 746.0
HKD2_k127_2009211_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.507e-199 637.0
HKD2_k127_2009211_2 arabinose-5-phosphate isomerase activity K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 327.0
HKD2_k127_2009211_3 lipopolysaccharide binding K09774 - - 0.000000000000000000000000000000000000000000000000000000000002785 226.0
HKD2_k127_2009211_4 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000001399 171.0
HKD2_k127_2009211_5 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00000000000000000000000000000000002242 142.0
HKD2_k127_2009211_6 Response regulator receiver domain - - - 0.000000000000000000000000178 112.0
HKD2_k127_2009211_7 Gaf domain K02003,K02484,K14986 - 2.7.13.3 0.0000000000000005129 80.0
HKD2_k127_2013559_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 1.595e-255 796.0
HKD2_k127_2013559_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000001571 197.0
HKD2_k127_2013559_2 - - - - 0.000000000000000000000000000000000000001024 153.0
HKD2_k127_2013559_3 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000000000000000003151 150.0
HKD2_k127_2013559_4 Carboxypeptidase regulatory-like domain K03641 - - 0.00000004778 64.0
HKD2_k127_2032141_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001262 253.0
HKD2_k127_2032141_1 cellulose binding - - - 0.000000000000000000000000000000000008544 157.0
HKD2_k127_2048935_0 Ferredoxin K00335,K05587,K17992,K18331 - 1.12.1.3,1.6.5.3 0.0 1067.0
HKD2_k127_2048935_1 iron-sulfur cluster assembly K00336,K18332 - 1.12.1.3,1.6.5.3 2.033e-311 960.0
HKD2_k127_2048935_2 iron-sulfur cluster assembly K02482 - 2.7.13.3 1.352e-236 745.0
HKD2_k127_2048935_3 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001538 239.0
HKD2_k127_2048935_4 2 iron, 2 sulfur cluster binding K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
HKD2_k127_2048935_5 FlgD Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000831 213.0
HKD2_k127_2048935_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000009198 190.0
HKD2_k127_2048935_7 - - - - 0.000000000000000000000000000000002968 130.0
HKD2_k127_2051352_0 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 2.677e-194 631.0
HKD2_k127_2051352_1 PFAM BNR Asp-box repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000001732 234.0
HKD2_k127_2051352_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
HKD2_k127_2051352_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000008263 186.0
HKD2_k127_207225_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.265e-251 797.0
HKD2_k127_207225_1 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 541.0
HKD2_k127_207225_2 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000004807 189.0
HKD2_k127_207225_3 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000005791 99.0
HKD2_k127_2081965_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000399 213.0
HKD2_k127_2081965_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000001539 183.0
HKD2_k127_2081965_2 YicC-like family, N-terminal region K03316 - - 0.000000000000000000000000000000000000001138 153.0
HKD2_k127_2214548_0 (ABC) transporter K06147,K18890 - - 1.882e-220 698.0
HKD2_k127_2214548_1 (ABC) transporter K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 574.0
HKD2_k127_2214548_2 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 572.0
HKD2_k127_2214548_3 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
HKD2_k127_2214548_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000002635 189.0
HKD2_k127_2220533_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 469.0
HKD2_k127_2220533_1 transcriptional regulator K13770 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000004324 179.0
HKD2_k127_2240978_0 membrane organization K03641,K07277 - - 4.892e-206 664.0
HKD2_k127_22449_0 Asparagine synthase K01953 - 6.3.5.4 1.678e-286 891.0
HKD2_k127_22449_1 LPS biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 581.0
HKD2_k127_22449_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
HKD2_k127_22449_11 SNO glutamine amidotransferase family K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001451 258.0
HKD2_k127_22449_12 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000007606 218.0
HKD2_k127_22449_13 ATP-grasp enzyme - - - 0.000000000000000000000000000000000000000000000000000000003097 214.0
HKD2_k127_22449_14 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000002315 191.0
HKD2_k127_22449_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000003886 147.0
HKD2_k127_22449_16 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.00000000000000000000000001573 113.0
HKD2_k127_22449_17 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000007108 119.0
HKD2_k127_22449_18 glycosyl transferase group 1 - - - 0.0000000000003581 82.0
HKD2_k127_22449_19 Maltose acetyltransferase K00661 - 2.3.1.79 0.0000000000004274 76.0
HKD2_k127_22449_2 UDP binding domain K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 490.0
HKD2_k127_22449_20 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0001827 53.0
HKD2_k127_22449_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 481.0
HKD2_k127_22449_4 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 475.0
HKD2_k127_22449_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 469.0
HKD2_k127_22449_6 methyltransferase activity K00563 - 2.1.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
HKD2_k127_22449_7 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 359.0
HKD2_k127_22449_8 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 351.0
HKD2_k127_22449_9 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 355.0
HKD2_k127_2261689_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 514.0
HKD2_k127_2261689_1 methyltransferase K16215 - 2.1.1.243 0.0000000000000000000000000000000000000000000000000000000000000004414 226.0
HKD2_k127_2261689_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000011 206.0
HKD2_k127_2261689_3 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000001647 151.0
HKD2_k127_2261689_4 Heavy-metal-associated domain - - - 0.000000006998 61.0
HKD2_k127_2430918_0 ATPase of the PP-loop superfamily implicated in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 575.0
HKD2_k127_2430918_1 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000007013 221.0
HKD2_k127_2430918_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000006109 153.0
HKD2_k127_2430918_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000004227 115.0
HKD2_k127_2430918_4 Glycosyl transferase family 2 - - - 0.000001438 50.0
HKD2_k127_2435729_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 256.0
HKD2_k127_2435729_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006625 256.0
HKD2_k127_2435729_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000001086 130.0
HKD2_k127_2435729_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000008698 107.0
HKD2_k127_2435729_4 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000002325 100.0
HKD2_k127_2446064_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 311.0
HKD2_k127_2446064_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000005078 143.0
HKD2_k127_2451123_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 391.0
HKD2_k127_2451123_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000006987 104.0
HKD2_k127_2451123_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000004806 89.0
HKD2_k127_2451123_3 regulation of translation K03733,K05808,K05809 - - 0.00000000001935 68.0
HKD2_k127_2466944_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 1.236e-239 765.0
HKD2_k127_2466944_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 333.0
HKD2_k127_2466944_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 313.0
HKD2_k127_2466944_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000006335 236.0
HKD2_k127_2466944_4 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
HKD2_k127_2466944_5 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.0000000000000000000000000000000000000000000005896 170.0
HKD2_k127_2466944_6 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.00000000000000000000000000000000000000000008223 168.0
HKD2_k127_2466944_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000006112 149.0
HKD2_k127_2467359_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000005661 111.0
HKD2_k127_2518516_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 4.071e-278 872.0
HKD2_k127_2518516_1 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.197e-233 729.0
HKD2_k127_2518516_10 lycopene cyclase - - - 0.0000000000009551 72.0
HKD2_k127_2518516_2 all-trans-retinol 13,14-reductase activity K01854,K09845,K10027 - 1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 481.0
HKD2_k127_2518516_3 Glycosyl transferases group 1 K12989 - - 0.00000000000000000000000000000000000000000000000000000000000000000001118 246.0
HKD2_k127_2518516_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000593 230.0
HKD2_k127_2518516_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000006742 208.0
HKD2_k127_2518516_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000006856 196.0
HKD2_k127_2518516_7 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000000000000000000000003798 193.0
HKD2_k127_2518516_8 lycopene cyclase - - - 0.00000000000000000002889 93.0
HKD2_k127_2518516_9 Carotenoid biosynthesis protein - - - 0.00000000000000000003279 100.0
HKD2_k127_2582041_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 6.4e-225 716.0
HKD2_k127_2582041_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009752 276.0
HKD2_k127_2582041_2 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000007195 268.0
HKD2_k127_2582041_3 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
HKD2_k127_2582041_4 negative regulation of ribosome biogenesis K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.000000000000000000000000000000005533 131.0
HKD2_k127_2582041_5 nucleotide catabolic process K05996 - 3.4.17.18 0.00000000000000000000001058 118.0
HKD2_k127_2582041_6 TRANSCRIPTIONal - - - 0.0000000000000000000002445 103.0
HKD2_k127_2582041_7 - - - - 0.000000000000000004675 91.0
HKD2_k127_2582041_8 Belongs to the UPF0312 family - - - 0.0000000000000006949 85.0
HKD2_k127_2583403_0 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 586.0
HKD2_k127_2583403_1 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000006228 176.0
HKD2_k127_2592904_0 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 412.0
HKD2_k127_2592904_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 398.0
HKD2_k127_2592904_2 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 385.0
HKD2_k127_2592904_3 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
HKD2_k127_2592904_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000184 239.0
HKD2_k127_2592904_5 FemAB family - - - 0.00000000000000000000000000000000000000000000000000008072 200.0
HKD2_k127_2592904_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000008486 149.0
HKD2_k127_2592904_7 Methyltransferase FkbM domain - - - 0.000000000001677 77.0
HKD2_k127_2592904_8 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000272 47.0
HKD2_k127_2641102_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 0.0 1128.0
HKD2_k127_2641102_1 Belongs to the aldehyde dehydrogenase family K00128,K06447 - 1.2.1.3,1.2.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 425.0
HKD2_k127_2641102_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 401.0
HKD2_k127_2641102_3 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
HKD2_k127_2641102_4 COG NOG22668 non supervised orthologous group - - - 0.000000000000000000000002428 111.0
HKD2_k127_2677795_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 425.0
HKD2_k127_2677795_1 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 348.0
HKD2_k127_2677795_2 4-alpha-glucanotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 359.0
HKD2_k127_2677795_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 308.0
HKD2_k127_2677795_4 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000005952 222.0
HKD2_k127_2677795_5 DinB family - - - 0.00000000000000000000000000000000000000000007278 165.0
HKD2_k127_2677795_6 tetratricopeptide repeat - - - 0.0000000000000002845 88.0
HKD2_k127_2677795_7 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000001609 87.0
HKD2_k127_2677795_8 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.000006192 59.0
HKD2_k127_2677795_9 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.00009942 55.0
HKD2_k127_2690126_0 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001051 270.0
HKD2_k127_2690126_1 mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000002722 229.0
HKD2_k127_2690126_2 - - - - 0.0000000000000000000000000000001239 128.0
HKD2_k127_2690126_3 Heat shock protein - - - 0.0000000000000000000000000001473 123.0
HKD2_k127_2690126_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000009202 58.0
HKD2_k127_2823123_0 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 8.225e-213 667.0
HKD2_k127_2823123_1 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 7.902e-196 625.0
HKD2_k127_2823123_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000383 85.0
HKD2_k127_2823123_2 ribonuclease E activity K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 545.0
HKD2_k127_2823123_3 Pfam Major Facilitator Superfamily K02429 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 513.0
HKD2_k127_2823123_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 465.0
HKD2_k127_2823123_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 447.0
HKD2_k127_2823123_6 Psort location Cytoplasmic, score 9.26 K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 315.0
HKD2_k127_2823123_7 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006098 263.0
HKD2_k127_2823123_8 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003312 256.0
HKD2_k127_2823123_9 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000002818 153.0
HKD2_k127_2850905_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 602.0
HKD2_k127_2850905_1 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 443.0
HKD2_k127_2850905_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 333.0
HKD2_k127_2850905_3 - - - - 0.0000000000000000000005265 106.0
HKD2_k127_2850905_4 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.000000000000000000001169 110.0
HKD2_k127_2850905_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000113 59.0
HKD2_k127_2891222_0 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 321.0
HKD2_k127_2891222_1 metal-sulfur cluster biosynthetic enzyme K02612,K03593,K04488 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 292.0
HKD2_k127_2891222_2 of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000003361 263.0
HKD2_k127_2891222_3 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000005312 214.0
HKD2_k127_2891222_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000001932 134.0
HKD2_k127_2899256_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000006313 239.0
HKD2_k127_2899256_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000005946 188.0
HKD2_k127_2899256_2 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000008395 173.0
HKD2_k127_2899256_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000002232 157.0
HKD2_k127_2899256_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000001696 140.0
HKD2_k127_2899256_5 Transglycosylase SLT domain - - - 0.000000000000000001056 98.0
HKD2_k127_2979198_0 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 515.0
HKD2_k127_2979198_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 402.0
HKD2_k127_2979198_2 COG3279 Response regulator of the LytR AlgR family - - - 0.000006696 52.0
HKD2_k127_2979750_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000001267 154.0
HKD2_k127_2979750_1 - - - - 0.000000000000000000006419 102.0
HKD2_k127_2979750_2 Photosynthesis system II assembly factor YCF48 - - - 0.00007072 56.0
HKD2_k127_3004741_0 radical SAM domain protein - - - 4.849e-196 619.0
HKD2_k127_3004741_1 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 595.0
HKD2_k127_3004741_2 Peptide-N-glycosidase F, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 388.0
HKD2_k127_3004741_3 peptide catabolic process K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 375.0
HKD2_k127_3004741_4 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 353.0
HKD2_k127_3004741_5 PFAM FecR protein K20276 - - 0.0000000000000000000000001373 125.0
HKD2_k127_3004741_6 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.00000000000000000000002248 116.0
HKD2_k127_3064187_0 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 349.0
HKD2_k127_3064187_1 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 324.0
HKD2_k127_3064187_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HKD2_k127_3097009_0 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 480.0
HKD2_k127_3097009_1 ATP-binding cassette protein, ChvD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 301.0
HKD2_k127_3097009_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001164 267.0
HKD2_k127_3097009_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001589 244.0
HKD2_k127_3097009_4 protein-(glutamine-N5) methyltransferase activity K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000001442 199.0
HKD2_k127_3097009_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000001141 151.0
HKD2_k127_3097009_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.000000000000000000000000000000000006878 142.0
HKD2_k127_3097009_7 Rossmann-like domain - - - 0.0000000000000000000000000005533 124.0
HKD2_k127_3121623_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1166.0
HKD2_k127_3121623_1 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 1.009e-244 760.0
HKD2_k127_3121623_2 exodeoxyribonuclease VII activity K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
HKD2_k127_3121623_3 cellulose binding - - - 0.00000000000000000000000000000000000000000006662 182.0
HKD2_k127_3121623_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000008176 133.0
HKD2_k127_3121623_5 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000008779 90.0
HKD2_k127_315847_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000001489 258.0
HKD2_k127_315847_1 His Kinase A (phosphoacceptor) domain K07709 - 2.7.13.3 0.0000008814 61.0
HKD2_k127_3164591_0 Involved in the tonB-independent uptake of proteins K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 309.0
HKD2_k127_3164591_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000004356 255.0
HKD2_k127_3164591_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000001381 184.0
HKD2_k127_3164591_3 protein related to plant photosystem II stability assembly factor - - - 0.000007511 51.0
HKD2_k127_316877_0 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 571.0
HKD2_k127_316877_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 491.0
HKD2_k127_316877_2 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 287.0
HKD2_k127_316877_3 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.00000000000000000000000000000000001536 143.0
HKD2_k127_316877_4 - - - - 0.0000004685 54.0
HKD2_k127_3279667_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 460.0
HKD2_k127_3279667_1 PFAM CHAD domain containing protein K08296 - - 0.00002636 55.0
HKD2_k127_3300895_0 acyl-CoA dehydrogenase activity K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 554.0
HKD2_k127_3300895_1 succinate-CoA ligase activity K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 507.0
HKD2_k127_3300895_10 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 314.0
HKD2_k127_3300895_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 278.0
HKD2_k127_3300895_12 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
HKD2_k127_3300895_13 GMP reductase activity K00088,K00364 - 1.1.1.205,1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009507 278.0
HKD2_k127_3300895_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003263 262.0
HKD2_k127_3300895_15 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000001889 229.0
HKD2_k127_3300895_16 oxidoreductase activity K17745 - 1.1.1.325 0.0000000000000000000000000000000000000000000000000000000007536 209.0
HKD2_k127_3300895_17 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000000000000000000000000000001925 192.0
HKD2_k127_3300895_18 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000008972 173.0
HKD2_k127_3300895_19 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000002889 150.0
HKD2_k127_3300895_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 487.0
HKD2_k127_3300895_20 Belongs to the peptidase S8 family K13276 - - 0.000000000000000009958 94.0
HKD2_k127_3300895_21 succinate dehydrogenase K00241 - - 0.0000000000000003082 83.0
HKD2_k127_3300895_22 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000834 81.0
HKD2_k127_3300895_23 histone H1-like protein - - - 0.000000001992 60.0
HKD2_k127_3300895_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 404.0
HKD2_k127_3300895_4 GTPase activity K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 400.0
HKD2_k127_3300895_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 392.0
HKD2_k127_3300895_6 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 378.0
HKD2_k127_3300895_7 DNA photolyase domain protein K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 381.0
HKD2_k127_3300895_8 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 344.0
HKD2_k127_3300895_9 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 324.0
HKD2_k127_3322470_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001026 289.0
HKD2_k127_3322470_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000431 299.0
HKD2_k127_3322470_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002907 274.0
HKD2_k127_3322470_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000002924 115.0
HKD2_k127_3322470_4 YbbR-like protein - - - 0.00000000000001635 83.0
HKD2_k127_3379957_0 proline dehydrogenase activity K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 333.0
HKD2_k127_3379957_1 Fumarylacetoacetase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 293.0
HKD2_k127_3379957_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000006487 97.0
HKD2_k127_3379957_3 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000001333 93.0
HKD2_k127_3409980_0 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 505.0
HKD2_k127_3409980_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 501.0
HKD2_k127_3433467_0 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 321.0
HKD2_k127_3433467_1 Chaperonin 10 Kd subunit - - - 0.0000000000000000000000000000000000000000000009268 168.0
HKD2_k127_3433467_2 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000003138 128.0
HKD2_k127_3526814_0 phosphorelay signal transduction system K03413 - - 6.308e-213 672.0
HKD2_k127_3526814_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HKD2_k127_3526814_10 cellulose binding - - - 0.0000000000000000000000000000000000007953 160.0
HKD2_k127_3526814_11 IMP dehydrogenase activity - - - 0.000000000000000000000000000000000001358 142.0
HKD2_k127_3526814_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000006084 121.0
HKD2_k127_3526814_13 Peptidase, M22 K14742 - - 0.000000000000000002091 93.0
HKD2_k127_3526814_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 434.0
HKD2_k127_3526814_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 405.0
HKD2_k127_3526814_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 378.0
HKD2_k127_3526814_5 photosystem II stabilization K02237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 326.0
HKD2_k127_3526814_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
HKD2_k127_3526814_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000018 301.0
HKD2_k127_3526814_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000225 156.0
HKD2_k127_3526814_9 Belongs to the aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000002829 146.0
HKD2_k127_3569612_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 479.0
HKD2_k127_3569612_1 transmembrane transport K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 466.0
HKD2_k127_3569612_2 ABC transporter (Permease) K02033,K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 359.0
HKD2_k127_3569612_3 microcin transport K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 336.0
HKD2_k127_3569612_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007242 258.0
HKD2_k127_3569612_5 pectinesterase activity - - - 0.0000000000000000000000000000000001564 142.0
HKD2_k127_3569612_6 self proteolysis K04771 - 3.4.21.107 0.000000000000000000000003781 108.0
HKD2_k127_3569612_7 cellulose binding - - - 0.00000000000000000002184 105.0
HKD2_k127_3610814_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 501.0
HKD2_k127_3610814_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003364 259.0
HKD2_k127_3610814_2 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.0000000000000000000000000000000000000001072 164.0
HKD2_k127_3610814_3 Virulence factor BrkB K07058 - - 0.000002203 59.0
HKD2_k127_366432_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 401.0
HKD2_k127_366432_1 chromate transport K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000001267 231.0
HKD2_k127_366432_2 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000054 171.0
HKD2_k127_366432_3 - - - - 0.00000000000000000000000000000000000001442 147.0
HKD2_k127_366432_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.0000000000000000000000000000000000004321 144.0
HKD2_k127_366432_5 cellulose binding - - - 0.0000000000000000002566 103.0
HKD2_k127_3806581_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.0 1160.0
HKD2_k127_3806581_1 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003881 246.0
HKD2_k127_3806581_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000007015 156.0
HKD2_k127_3806581_3 Protein of unknown function (DUF2721) - - - 0.00000000000003027 75.0
HKD2_k127_3818014_0 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 483.0
HKD2_k127_3818014_1 PFAM Copper amine - - - 0.000000000000000000000000000000000000005071 158.0
HKD2_k127_3818014_2 Subtilase family - - - 0.00000000000000000000272 108.0
HKD2_k127_3823762_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 347.0
HKD2_k127_3823762_1 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 262.0
HKD2_k127_3823762_2 cellulose binding - - - 0.00000000000000000000000000000000000000003401 169.0
HKD2_k127_3826042_0 aconitate hydratase activity K01681 - 4.2.1.3 0.0 1105.0
HKD2_k127_3826042_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 597.0
HKD2_k127_3826042_10 COG0607 Rhodanese-related sulfurtransferase K03151 - 2.8.1.4 0.0000000000000000007201 91.0
HKD2_k127_3826042_12 Glycine cleavage H-protein - - - 0.0000000007885 68.0
HKD2_k127_3826042_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 587.0
HKD2_k127_3826042_3 extracellular polysaccharide biosynthetic process K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 550.0
HKD2_k127_3826042_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 526.0
HKD2_k127_3826042_5 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 489.0
HKD2_k127_3826042_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 388.0
HKD2_k127_3826042_7 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 403.0
HKD2_k127_3826042_8 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001002 281.0
HKD2_k127_3826042_9 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000000000000000001344 182.0
HKD2_k127_3846788_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.303e-272 844.0
HKD2_k127_3846788_1 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 508.0
HKD2_k127_3846788_10 ABC transporter K19340 - - 0.0000000000000000000000000000000000000000000000000005506 192.0
HKD2_k127_3846788_11 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000177 183.0
HKD2_k127_3846788_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000001441 148.0
HKD2_k127_3846788_13 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000009425 155.0
HKD2_k127_3846788_14 cellulose binding - - - 0.0000000000000000000000000001249 119.0
HKD2_k127_3846788_15 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000005816 114.0
HKD2_k127_3846788_16 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000007598 119.0
HKD2_k127_3846788_17 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000001164 117.0
HKD2_k127_3846788_18 exo-alpha-(2->6)-sialidase activity - - - 0.0000002585 61.0
HKD2_k127_3846788_19 cellulose binding - - - 0.0001075 47.0
HKD2_k127_3846788_2 metalloendopeptidase activity K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 419.0
HKD2_k127_3846788_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 412.0
HKD2_k127_3846788_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 386.0
HKD2_k127_3846788_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 307.0
HKD2_k127_3846788_6 tRNA dimethylallyltransferase activity K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002937 281.0
HKD2_k127_3846788_7 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
HKD2_k127_3846788_8 nitrous oxide K19341 - - 0.00000000000000000000000000000000000000000000000000001082 198.0
HKD2_k127_3846788_9 Protein of unknown function (DUF2400) K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000007142 195.0
HKD2_k127_387841_0 mismatched DNA binding K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1028.0
HKD2_k127_387841_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
HKD2_k127_387841_2 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000003005 196.0
HKD2_k127_387841_3 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 - 2.1.1.182,2.1.1.184 0.000000001003 61.0
HKD2_k127_3899878_0 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000002501 249.0
HKD2_k127_3899878_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000002436 203.0
HKD2_k127_3899878_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000005805 126.0
HKD2_k127_3899878_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000181 111.0
HKD2_k127_3899878_4 Exodeoxyribonuclease III - - - 0.00000000000000000000007051 99.0
HKD2_k127_3929068_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 324.0
HKD2_k127_3929068_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004437 279.0
HKD2_k127_3929068_2 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001517 258.0
HKD2_k127_3929068_3 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000003106 191.0
HKD2_k127_3929068_4 Appr-1'-p processing enzyme - - - 0.0000000000000000001141 89.0
HKD2_k127_3929068_5 CYTH - - - 0.000000000003227 74.0
HKD2_k127_3966398_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 407.0
HKD2_k127_4031_0 nucleotide-excision repair K03701 - - 2.53e-317 999.0
HKD2_k127_4031_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 448.0
HKD2_k127_4031_2 MFS_1 like family K08161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004725 275.0
HKD2_k127_4031_3 metallocarboxypeptidase activity K01206,K01218 - 3.2.1.51,3.2.1.78 0.0000000000000000000000000000000000000000000001597 174.0
HKD2_k127_4031_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000001503 166.0
HKD2_k127_4031_5 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000002692 111.0
HKD2_k127_4031_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000006836 74.0
HKD2_k127_40478_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 366.0
HKD2_k127_40478_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 342.0
HKD2_k127_40478_2 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 298.0
HKD2_k127_40478_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000006045 220.0
HKD2_k127_40478_4 histidyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000004261 206.0
HKD2_k127_40478_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000002915 59.0
HKD2_k127_4081821_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.939e-212 683.0
HKD2_k127_4081821_1 translation release factor activity K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 454.0
HKD2_k127_4081821_2 lipoprotein localization to outer membrane K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 289.0
HKD2_k127_4081821_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
HKD2_k127_4081821_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000001739 158.0
HKD2_k127_4081821_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.0000000000000000000000000009103 117.0
HKD2_k127_4081821_6 cellulose binding - - - 0.00000000000000000000004143 111.0
HKD2_k127_4081821_7 - - - - 0.00000000000000000001939 96.0
HKD2_k127_4082814_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 296.0
HKD2_k127_4082814_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005527 271.0
HKD2_k127_4082814_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000001793 160.0
HKD2_k127_4082814_3 nuclear chromosome segregation - - - 0.00000000000000000000000226 117.0
HKD2_k127_4082814_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000005234 54.0
HKD2_k127_4082814_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000006218 55.0
HKD2_k127_4086319_0 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 295.0
HKD2_k127_4086319_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000835 219.0
HKD2_k127_4086319_2 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000006185 147.0
HKD2_k127_4089411_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 1.386e-223 704.0
HKD2_k127_4089411_1 phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001774 235.0
HKD2_k127_4089411_2 - - - - 0.00000000000000000000000000000000000000000000000000000000003884 212.0
HKD2_k127_4089411_3 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000002649 177.0
HKD2_k127_4089411_4 cellulose binding - - - 0.000000000000000000000000000000000000003183 164.0
HKD2_k127_4089411_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000008699 106.0
HKD2_k127_4089411_6 pectinesterase activity K10297,K15923,K18197 - 3.2.1.51,4.2.2.23 0.00000000000000000000003584 104.0
HKD2_k127_4089411_7 regulation of translation K03530,K05788 - - 0.00000000000000000003418 90.0
HKD2_k127_4092253_0 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000002789 182.0
HKD2_k127_4092253_1 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000004122 166.0
HKD2_k127_4092253_2 Tetratricopeptide repeat - - - 0.00000000000000000004552 106.0
HKD2_k127_4092253_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00006689 49.0
HKD2_k127_4092253_4 cell division protein - - - 0.000858 52.0
HKD2_k127_4111711_0 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 594.0
HKD2_k127_4111711_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000286 133.0
HKD2_k127_4111711_2 Asparagine synthase - - - 0.0003489 51.0
HKD2_k127_4125629_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 346.0
HKD2_k127_4125629_1 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004595 262.0
HKD2_k127_4125629_2 domain protein K01113,K20276 - 3.1.3.1 0.000000000000000000000000000000000000000000000002658 188.0
HKD2_k127_4125629_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000003595 149.0
HKD2_k127_4125629_4 polysaccharide deacetylase - - - 0.000000000000000000001018 108.0
HKD2_k127_4161669_0 lactate metabolic process - - - 2.062e-237 751.0
HKD2_k127_4161669_1 methionine adenosyltransferase activity K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 559.0
HKD2_k127_4161669_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001632 163.0
HKD2_k127_4161669_3 PFAM Uncharacterised ACR, COG1259 K03617,K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000003403 149.0
HKD2_k127_4161669_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000002015 91.0
HKD2_k127_4161669_5 Domain of unknown function (DUF4905) - - - 0.0000000000001846 80.0
HKD2_k127_4199321_0 Sortilin, neurotensin receptor 3, - - - 8.038e-204 651.0
HKD2_k127_4199321_1 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000217 262.0
HKD2_k127_4199321_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000001509 115.0
HKD2_k127_4206259_0 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005298 263.0
HKD2_k127_4206259_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.000000000000000000000000000000000000002317 155.0
HKD2_k127_4206259_2 unsaturated fatty acid biosynthetic process K09836 - - 0.0000000000000000000000000000000007236 132.0
HKD2_k127_4257423_0 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 544.0
HKD2_k127_4257423_1 glycogen (starch) synthase activity K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 459.0
HKD2_k127_4257423_2 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 320.0
HKD2_k127_4257423_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 302.0
HKD2_k127_4257423_4 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000009248 276.0
HKD2_k127_4257423_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000002689 201.0
HKD2_k127_4257423_6 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000001305 156.0
HKD2_k127_4257423_7 oxidoreductase activity - - - 0.00000000000000000000001776 117.0
HKD2_k127_4276796_0 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000001367 178.0
HKD2_k127_4276796_1 Yip1 domain - - - 0.000000000000000000003064 103.0
HKD2_k127_4276796_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000001971 82.0
HKD2_k127_4281476_0 lipopolysaccharide transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 576.0
HKD2_k127_4281476_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 322.0
HKD2_k127_4281476_2 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000002255 231.0
HKD2_k127_4281476_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000007359 235.0
HKD2_k127_4281476_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000007793 183.0
HKD2_k127_4281476_5 TPM domain K06872 - - 0.00000000000000000000000000000000000000000002026 171.0
HKD2_k127_4281476_6 Membrane K08988 - - 0.00000000000000000000000008992 114.0
HKD2_k127_4281476_7 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000001663 103.0
HKD2_k127_4281476_8 STAS domain K04749 - - 0.000000000000001567 81.0
HKD2_k127_4281476_9 Biopolymer transport protein ExbD/TolR - - - 0.00000000000003426 80.0
HKD2_k127_4312702_0 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001001 237.0
HKD2_k127_4312702_1 - - - - 0.00000000000000000000000000000001389 140.0
HKD2_k127_4320726_0 aerobic electron transport chain K00425 - 1.10.3.14 7.253e-202 637.0
HKD2_k127_4320726_1 secreted protein - - - 1.604e-199 640.0
HKD2_k127_4320726_10 - - - - 0.0000000002552 70.0
HKD2_k127_4320726_2 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 492.0
HKD2_k127_4320726_3 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 460.0
HKD2_k127_4320726_4 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 325.0
HKD2_k127_4320726_5 Rubredoxin - - - 0.00000000000000000000000000000000000000000002951 169.0
HKD2_k127_4320726_6 - - - - 0.00000000000000000000000000000000000113 144.0
HKD2_k127_4320726_7 Haem-binding domain - - - 0.00000000000000000000000000000000001301 141.0
HKD2_k127_4320726_8 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000003764 127.0
HKD2_k127_4320726_9 lipolytic protein G-D-S-L family - - - 0.0000000000000004001 90.0
HKD2_k127_4341860_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 563.0
HKD2_k127_4341860_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
HKD2_k127_4341860_2 Psort location Cytoplasmic, score - - - 0.00000003473 65.0
HKD2_k127_4368191_0 iron-nicotianamine transmembrane transporter activity - - - 6.665e-296 920.0
HKD2_k127_4368191_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 558.0
HKD2_k127_4368191_2 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000000000003737 155.0
HKD2_k127_4368191_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000961 123.0
HKD2_k127_4368191_4 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000000000001985 82.0
HKD2_k127_4377853_0 symporter activity K03307 - - 3.042e-235 740.0
HKD2_k127_4377853_1 penicillin binding K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 523.0
HKD2_k127_4377853_10 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000001743 152.0
HKD2_k127_4377853_11 rod shape-determining protein MreD K03571 - - 0.0000002551 59.0
HKD2_k127_4377853_2 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 402.0
HKD2_k127_4377853_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 376.0
HKD2_k127_4377853_4 peptidoglycan glycosyltransferase activity K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 344.0
HKD2_k127_4377853_5 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000001375 252.0
HKD2_k127_4377853_6 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001546 218.0
HKD2_k127_4377853_7 Orotidine 5''-phosphate decarboxylase K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000001733 209.0
HKD2_k127_4377853_8 regulation of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000005448 202.0
HKD2_k127_4377853_9 - - - - 0.0000000000000000000000000000000000000000000000007397 183.0
HKD2_k127_4399988_0 bacterial-type flagellum-dependent cell motility - - - 5.124e-210 691.0
HKD2_k127_4399988_1 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 351.0
HKD2_k127_440793_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000242 229.0
HKD2_k127_440793_1 Opacity protein - - - 0.000006826 56.0
HKD2_k127_445643_0 CoA carboxylase activity K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 492.0
HKD2_k127_445643_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 395.0
HKD2_k127_4458260_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
HKD2_k127_4458260_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003348 238.0
HKD2_k127_4458260_2 amino acid activation for nonribosomal peptide biosynthetic process K02406 - - 0.00000000000000000000000001765 116.0
HKD2_k127_4458260_3 Regulatory protein RecX K03565 - - 0.0000000000000000000000001256 114.0
HKD2_k127_4458260_4 Putative auto-transporter adhesin, head GIN domain - - - 0.0000001118 63.0
HKD2_k127_4462602_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 1.691e-317 982.0
HKD2_k127_4462602_1 response to heat K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 587.0
HKD2_k127_4462602_10 lipoprotein transporter activity K02003,K02004,K09810 - - 0.000000000000000000000000000000000000000000000000000000000001078 216.0
HKD2_k127_4462602_11 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000000000000000001096 203.0
HKD2_k127_4462602_12 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000001396 195.0
HKD2_k127_4462602_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000001266 163.0
HKD2_k127_4462602_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000005288 149.0
HKD2_k127_4462602_15 NosL K19342 - - 0.0000000000000000000000000000001698 128.0
HKD2_k127_4462602_16 chromosome segregation K03497 - - 0.000000000000000000005454 103.0
HKD2_k127_4462602_17 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000007831 61.0
HKD2_k127_4462602_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 494.0
HKD2_k127_4462602_3 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 381.0
HKD2_k127_4462602_4 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 374.0
HKD2_k127_4462602_5 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 358.0
HKD2_k127_4462602_6 lipoprotein localization to outer membrane K09808,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 327.0
HKD2_k127_4462602_7 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 308.0
HKD2_k127_4462602_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 301.0
HKD2_k127_4462602_9 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000753 257.0
HKD2_k127_4475747_0 TonB-dependent receptor - - - 1.733e-202 654.0
HKD2_k127_4475747_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 294.0
HKD2_k127_4475747_2 AMMECR1 K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003372 284.0
HKD2_k127_4475747_3 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001228 250.0
HKD2_k127_4475747_4 Transposase IS200 like - - - 0.000000000000000000000000000000003639 136.0
HKD2_k127_4475747_5 Cation transport ATPase K17686 - 3.6.3.54 0.000000000001011 74.0
HKD2_k127_4487611_0 iron ion binding - - - 0.0000000000000000000000000000000000000000000000000000000001258 210.0
HKD2_k127_4487611_1 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.000000000000000000000000000000000000000000000004148 187.0
HKD2_k127_4487611_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000113 132.0
HKD2_k127_4487611_3 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000006481 85.0
HKD2_k127_4487611_4 Trypsin-like serine protease - - - 0.000000000004178 79.0
HKD2_k127_4500951_0 Peptidase, S9A B C family, catalytic domain protein - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 524.0
HKD2_k127_4500951_1 Oligoendopeptidase f K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
HKD2_k127_4555698_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000006469 227.0
HKD2_k127_4555698_1 - - - - 0.0000000000000000000000000000003512 128.0
HKD2_k127_4555698_2 Globin - - - 0.000000000000000000000001781 107.0
HKD2_k127_4555698_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000002863 79.0
HKD2_k127_4590981_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 559.0
HKD2_k127_4590981_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 391.0
HKD2_k127_4590981_2 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000303 251.0
HKD2_k127_4590981_3 acetyltransferase K18815 - 2.3.1.82 0.00000000000000000000000000000000000000121 152.0
HKD2_k127_4590981_4 Probably functions as a manganese efflux pump - - - 0.000000000000000000000001032 105.0
HKD2_k127_4641905_0 nuclear chromosome segregation K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 619.0
HKD2_k127_4641905_1 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
HKD2_k127_4641905_2 L-methionine salvage from methylthioadenosine K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000003975 164.0
HKD2_k127_4658222_0 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 8.644e-217 691.0
HKD2_k127_4658222_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 318.0
HKD2_k127_4658222_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000001386 185.0
HKD2_k127_4658222_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000001398 172.0
HKD2_k127_4658222_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000003512 137.0
HKD2_k127_4658222_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000001186 104.0
HKD2_k127_4723389_0 IMP dehydrogenase activity K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 2.194e-203 641.0
HKD2_k127_4723389_1 phosphorylase activity K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 443.0
HKD2_k127_4723389_2 competence protein COMEC K02238 - - 0.00000000000000000000000000000000000000000000000000000001976 217.0
HKD2_k127_4723389_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000001648 119.0
HKD2_k127_4784817_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 551.0
HKD2_k127_4784817_1 DEAD DEAH box helicase K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 321.0
HKD2_k127_4784817_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 291.0
HKD2_k127_4784817_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000001681 220.0
HKD2_k127_4784817_4 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 0.000000007438 57.0
HKD2_k127_4789549_0 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 328.0
HKD2_k127_4789549_1 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001387 218.0
HKD2_k127_4789549_2 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000003703 145.0
HKD2_k127_4842195_0 - - - - 1.315e-258 850.0
HKD2_k127_4842195_1 membrane organization K07126,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 419.0
HKD2_k127_4845169_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000003979 201.0
HKD2_k127_4845169_1 transferase activity, transferring glycosyl groups K02359,K11740,K19003 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.4.1.336 0.0000000000000000000000000000000000000000000001348 186.0
HKD2_k127_4845169_2 Glycosyltransferase like family 2 K11740 - - 0.00000000000000000000000001028 124.0
HKD2_k127_4845169_3 - - - - 0.000000000000000000001123 111.0
HKD2_k127_4845169_4 ABC transporter K01990 - - 0.000000009622 68.0
HKD2_k127_4881164_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 583.0
HKD2_k127_4881164_1 DinB family - - - 0.00000000000000000000000000000000000000000002951 166.0
HKD2_k127_4881164_2 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000001316 129.0
HKD2_k127_4881164_3 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000003748 104.0
HKD2_k127_4881164_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000001164 63.0
HKD2_k127_4964112_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 575.0
HKD2_k127_4964112_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 314.0
HKD2_k127_4964112_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000625 189.0
HKD2_k127_4964112_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000006621 89.0
HKD2_k127_4964112_4 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.00005745 53.0
HKD2_k127_4964112_5 response to antibiotic K21463 - - 0.0002762 46.0
HKD2_k127_4988403_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 1.225e-246 772.0
HKD2_k127_4988403_1 cellulose binding - - - 0.00000000000000000000000000000000000000000001385 184.0
HKD2_k127_5022754_0 PFAM glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001406 279.0
HKD2_k127_5022754_1 Acyltransferase - - - 0.00000000000000000000000000000000000000008212 160.0
HKD2_k127_5022754_2 PFAM regulatory protein, MerR K22491 - - 0.0000003559 58.0
HKD2_k127_5022754_3 cobalamin binding K03496,K22491 - - 0.0000003758 55.0
HKD2_k127_5031485_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 484.0
HKD2_k127_5031485_1 purine-nucleoside phosphorylase activity K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 287.0
HKD2_k127_5031485_10 ErfK YbiS YcfS YnhG family protein - - - 0.00000001713 66.0
HKD2_k127_5031485_11 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000957 46.0
HKD2_k127_5031485_12 SMART helix-turn-helix domain protein - - - 0.0005282 52.0
HKD2_k127_5031485_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 265.0
HKD2_k127_5031485_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000002215 217.0
HKD2_k127_5031485_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000002405 179.0
HKD2_k127_5031485_5 - - - - 0.000000000000000000000000000000000000000000002869 169.0
HKD2_k127_5031485_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000002291 169.0
HKD2_k127_5031485_7 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000002482 114.0
HKD2_k127_5031485_8 - - - - 0.000000000000000000002076 101.0
HKD2_k127_5031485_9 PFAM DivIVA family protein K04074 - - 0.00000000000000004091 89.0
HKD2_k127_5064182_0 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 347.0
HKD2_k127_5064182_1 cellulose binding - - - 0.0000000000000000000000000000000000001918 156.0
HKD2_k127_5064182_2 - - - - 0.0000000000000000003102 102.0
HKD2_k127_5064182_3 guanyl-nucleotide exchange factor activity - - - 0.0000003934 51.0
HKD2_k127_5081438_0 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.000000000000000000000000000000000000000000002719 187.0
HKD2_k127_5101814_0 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000006346 203.0
HKD2_k127_5101814_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000001719 145.0
HKD2_k127_5101814_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000003356 53.0
HKD2_k127_5101846_0 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 496.0
HKD2_k127_5101846_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000012 104.0
HKD2_k127_5101846_2 Peptidase family M13 K01415,K07386 - 3.4.24.71 0.0000000000000000000006496 96.0
HKD2_k127_5115348_0 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 572.0
HKD2_k127_5115348_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 308.0
HKD2_k127_512396_0 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 374.0
HKD2_k127_512396_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000003157 211.0
HKD2_k127_512396_2 TIGRFAM rfaE bifunctional protein - - - 0.0000000000000000000000000000000000000000000001914 173.0
HKD2_k127_512396_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000524 79.0
HKD2_k127_5151270_0 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
HKD2_k127_5151270_1 tRNA wobble adenosine to inosine editing K11991 GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.0000000000000000000000000000000000000000000006889 171.0
HKD2_k127_5151270_2 phosphoenolpyruvate-dependent sugar phosphotransferase system K11189 - - 0.0000000000000000000000000000007104 123.0
HKD2_k127_5151270_3 Aldo/keto reductase family - - - 0.000000005028 66.0
HKD2_k127_5291495_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.485e-247 782.0
HKD2_k127_5291495_1 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 368.0
HKD2_k127_5291495_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001343 258.0
HKD2_k127_5291495_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000002465 170.0
HKD2_k127_5291495_4 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.0000000000000000000000000002191 123.0
HKD2_k127_5292023_0 nucleotide-excision repair K03701 - - 0.0 1195.0
HKD2_k127_5292023_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 569.0
HKD2_k127_5292023_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 437.0
HKD2_k127_5292023_3 Asparaginase K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
HKD2_k127_5292023_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 308.0
HKD2_k127_5292023_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000001308 169.0
HKD2_k127_5292023_6 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.0000000000000000000000000000000000000000163 161.0
HKD2_k127_5292023_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000064 115.0
HKD2_k127_5292023_8 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000007392 85.0
HKD2_k127_5295474_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 497.0
HKD2_k127_5295474_1 protein histidine kinase activity K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 347.0
HKD2_k127_5295474_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000003831 128.0
HKD2_k127_5303245_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 346.0
HKD2_k127_5303245_1 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 337.0
HKD2_k127_5303245_2 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 338.0
HKD2_k127_5303245_3 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 308.0
HKD2_k127_5303245_4 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002967 254.0
HKD2_k127_5303245_5 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000002237 216.0
HKD2_k127_5303245_6 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000005986 61.0
HKD2_k127_5315504_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000005114 179.0
HKD2_k127_5315504_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000002571 170.0
HKD2_k127_531761_0 Major facilitator Superfamily - - - 3.614e-197 624.0
HKD2_k127_531761_1 Psort location CytoplasmicMembrane, score 10.00 K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 502.0
HKD2_k127_5334894_0 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 434.0
HKD2_k127_5334894_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 393.0
HKD2_k127_5334894_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000001183 218.0
HKD2_k127_5334894_3 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000144 109.0
HKD2_k127_5344059_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 361.0
HKD2_k127_5344059_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004848 275.0
HKD2_k127_5344059_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000007085 99.0
HKD2_k127_5344059_3 - - - - 0.000000000000000001034 89.0
HKD2_k127_5344059_4 - - - - 0.000000000000001736 82.0
HKD2_k127_5357306_0 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000006228 263.0
HKD2_k127_5357306_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000001111 246.0
HKD2_k127_5357306_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000004988 203.0
HKD2_k127_5357306_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000004691 193.0
HKD2_k127_5357306_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000003379 182.0
HKD2_k127_5357306_5 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000008112 152.0
HKD2_k127_5357306_6 cellulose binding - - - 0.00000000000000000000000002546 123.0
HKD2_k127_5388861_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 405.0
HKD2_k127_5388861_2 YtkA-like - - - 0.00000000000000001486 92.0
HKD2_k127_5388861_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000006864 53.0
HKD2_k127_5388861_4 Protein involved in meta-pathway of phenol degradation - - - 0.0003404 52.0
HKD2_k127_5392584_0 acetyl-CoA hydrolase activity K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 516.0
HKD2_k127_5392584_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 329.0
HKD2_k127_5392584_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 290.0
HKD2_k127_5392584_3 AI-2E family transporter K11744 - - 0.000000000000000000000000000000000000000000000003595 187.0
HKD2_k127_5392584_4 pectinesterase activity K10297,K15923,K18197 - 3.2.1.51,4.2.2.23 0.0000000000000000000001143 113.0
HKD2_k127_543468_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 355.0
HKD2_k127_543468_1 Amino acid kinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000006671 241.0
HKD2_k127_543468_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000006193 208.0
HKD2_k127_543468_3 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000305 121.0
HKD2_k127_5445_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K03205 - - 0.000000000000000004466 93.0
HKD2_k127_5445_1 PFAM Family of - - - 0.0000000000009628 82.0
HKD2_k127_5506857_0 cystathionine gamma-synthase activity K01739,K01740,K01758,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.1,4.4.1.11,4.4.1.8 1.108e-196 620.0
HKD2_k127_5506857_1 mercury ion transmembrane transporter activity K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 369.0
HKD2_k127_5506857_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K18348 - 5.1.1.1,5.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 310.0
HKD2_k127_5506857_3 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000002344 70.0
HKD2_k127_5517212_0 response to heat K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 566.0
HKD2_k127_5517212_1 (ABC) transporter K02021,K06147,K06148,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 554.0
HKD2_k127_5517212_10 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000001632 132.0
HKD2_k127_5517212_11 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000005865 110.0
HKD2_k127_5517212_12 MlaD protein K02067 - - 0.0000000000000000000000008658 114.0
HKD2_k127_5517212_13 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000004359 94.0
HKD2_k127_5517212_14 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000001947 88.0
HKD2_k127_5517212_15 -O-antigen - - - 0.00000000000000000828 96.0
HKD2_k127_5517212_17 DNA-binding protein - - - 0.0000004717 58.0
HKD2_k127_5517212_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 536.0
HKD2_k127_5517212_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 417.0
HKD2_k127_5517212_4 fatty acid biosynthetic process K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 327.0
HKD2_k127_5517212_5 Glycosyl transferase, family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004086 256.0
HKD2_k127_5517212_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.000000000000000000000000000000000000000000000001835 177.0
HKD2_k127_5517212_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000003981 172.0
HKD2_k127_5517212_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000007659 145.0
HKD2_k127_5517212_9 - - - - 0.00000000000000000000000000000004786 139.0
HKD2_k127_5534489_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 467.0
HKD2_k127_5534489_1 peptide catabolic process K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 392.0
HKD2_k127_5534489_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000003251 160.0
HKD2_k127_5534489_3 metallopeptidase activity K07407 - 3.2.1.22 0.00000000000000000000003011 116.0
HKD2_k127_5534489_4 Monogalactosyldiacylglycerol synthase K03715 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006643,GO:0006664,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0008194,GO:0008378,GO:0008610,GO:0009058,GO:0009247,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009657,GO:0009668,GO:0009706,GO:0009790,GO:0009791,GO:0009793,GO:0009941,GO:0009987,GO:0010027,GO:0010154,GO:0016020,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0019866,GO:0022414,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0032501,GO:0032502,GO:0035250,GO:0042170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0046509,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061024,GO:0061458,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.46 0.00000000000000946 84.0
HKD2_k127_5534489_5 FecR protein - - - 0.00001121 57.0
HKD2_k127_5536009_0 CoA carboxylase activity K01966 - 2.1.3.15,6.4.1.3 3.454e-278 861.0
HKD2_k127_5536009_1 Conserved carboxylase domain K01571,K01960 - 4.1.1.3,6.4.1.1 1.155e-205 655.0
HKD2_k127_5536009_2 CoA carboxylase activity K01965 - 6.4.1.3 0.0000000000000000000000000000000000000004017 153.0
HKD2_k127_5536009_3 Transposase IS200 like - - - 0.000000000000000000000000000000000000001483 153.0
HKD2_k127_5536009_4 NHL repeat containing protein - - - 0.00000000000000000000000006052 121.0
HKD2_k127_5536009_5 PhoQ Sensor - - - 0.00000001285 66.0
HKD2_k127_5545747_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 435.0
HKD2_k127_5545747_1 COGs COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 383.0
HKD2_k127_5545747_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 381.0
HKD2_k127_5545747_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 287.0
HKD2_k127_5545747_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000008806 154.0
HKD2_k127_5545747_5 PFAM ABC transporter related - - - 0.0000000000000000000000000000001146 127.0
HKD2_k127_5545747_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000115 112.0
HKD2_k127_5562404_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 533.0
HKD2_k127_5562404_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000001123 166.0
HKD2_k127_5562404_2 arsenite transmembrane transporter activity - - - 0.000000000000000000000002377 104.0
HKD2_k127_5562404_3 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000006254 94.0
HKD2_k127_5562404_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000003042 64.0
HKD2_k127_5584798_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1146.0
HKD2_k127_5584798_1 Pfam:DUF377 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 568.0
HKD2_k127_5584798_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 494.0
HKD2_k127_5584798_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 448.0
HKD2_k127_5584798_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 402.0
HKD2_k127_5584798_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
HKD2_k127_5584798_6 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000005172 241.0
HKD2_k127_5584798_7 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000004483 147.0
HKD2_k127_5584798_8 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000000000518 146.0
HKD2_k127_5601194_0 Protein of unknown function (DUF2867) - - - 4.849e-216 679.0
HKD2_k127_5601194_1 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 368.0
HKD2_k127_5601194_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008312 278.0
HKD2_k127_5601194_3 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000231 171.0
HKD2_k127_5601194_4 Endonuclease I - - - 0.0000000000000000000000000003871 123.0
HKD2_k127_5601194_5 chlorophyll binding K03651,K03771,K07017 - 3.1.4.53,5.2.1.8 0.0000000000000000000000000008529 129.0
HKD2_k127_5601194_6 Exodeoxyribonuclease III - - - 0.0000000000000000000000000105 126.0
HKD2_k127_5601194_7 peptidase C11 clostripain - - - 0.0000009674 60.0
HKD2_k127_5639646_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.84e-204 644.0
HKD2_k127_5639646_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 583.0
HKD2_k127_5639646_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005996,GO:0006006,GO:0006139,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009117,GO:0009141,GO:0009147,GO:0009200,GO:0009211,GO:0009219,GO:0009225,GO:0009226,GO:0009262,GO:0009394,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019299,GO:0019300,GO:0019305,GO:0019318,GO:0019319,GO:0019438,GO:0019637,GO:0019692,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0045226,GO:0046075,GO:0046364,GO:0046379,GO:0046383,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 461.0
HKD2_k127_5639646_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 320.0
HKD2_k127_5639646_4 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007532 278.0
HKD2_k127_5639646_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HKD2_k127_5639646_6 single-stranded DNA binding K03629,K07459 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001197 239.0
HKD2_k127_5639646_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000001519 223.0
HKD2_k127_5639646_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000002889 184.0
HKD2_k127_5639646_9 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000001141 55.0
HKD2_k127_5656971_0 Pyruvate formate lyase-like K00656,K18427 - 2.3.1.54,4.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
HKD2_k127_5656971_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
HKD2_k127_5692543_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 612.0
HKD2_k127_5692543_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 348.0
HKD2_k127_5692543_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 297.0
HKD2_k127_5692543_3 peptidase activity, acting on L-amino acid peptides K03385 - 1.7.2.2 0.0002257 53.0
HKD2_k127_5706311_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 458.0
HKD2_k127_5706311_1 PQ loop repeat K15383 - - 0.000000000000000151 82.0
HKD2_k127_5706311_2 - - - - 0.0000000000000002512 91.0
HKD2_k127_5706311_3 PFAM Rieske 2Fe-2S domain K02636 - 1.10.9.1 0.0000000000001079 76.0
HKD2_k127_5768006_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 298.0
HKD2_k127_5768006_1 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
HKD2_k127_5768006_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000001503 131.0
HKD2_k127_5773924_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001005 249.0
HKD2_k127_5773924_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000004357 207.0
HKD2_k127_5773924_2 Glycosyltransferase, group 2 family protein K07011 - - 0.00000000000000000000000001551 121.0
HKD2_k127_5773924_3 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.00000000001424 68.0
HKD2_k127_5773924_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000001495 67.0
HKD2_k127_5779673_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 383.0
HKD2_k127_5779673_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000002696 255.0
HKD2_k127_5779673_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000006121 229.0
HKD2_k127_5793755_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 554.0
HKD2_k127_5793755_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 469.0
HKD2_k127_5793755_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 337.0
HKD2_k127_5793755_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000001281 169.0
HKD2_k127_5816110_0 Peptidase family M49 - - - 4.914e-210 665.0
HKD2_k127_5816110_1 Xaa-His dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 599.0
HKD2_k127_5816110_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000003598 250.0
HKD2_k127_5816110_3 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000001576 112.0
HKD2_k127_5816110_4 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000003375 118.0
HKD2_k127_5816110_5 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000001625 119.0
HKD2_k127_5816110_6 - - - - 0.000000001141 64.0
HKD2_k127_5825825_0 Carbamoyl-phosphate synthetase large chain domain protein K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 464.0
HKD2_k127_5825825_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 297.0
HKD2_k127_5825825_2 Tubulin like - - - 0.000000000000000000000000000000000000000000000000000000003203 220.0
HKD2_k127_5840128_0 transcription-coupled nucleotide-excision repair, DNA damage recognition K03723,K05365 - 2.4.1.129,3.4.16.4 6.424e-209 677.0
HKD2_k127_5840128_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000007509 108.0
HKD2_k127_5857455_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000002249 160.0
HKD2_k127_5857455_1 cellulose binding - - - 0.000000000000000000000000000002564 130.0
HKD2_k127_5857455_2 Exodeoxyribonuclease III - - - 0.000000000000000000000001199 118.0
HKD2_k127_5857455_3 xylan catabolic process K01179,K03932 - 3.2.1.4 0.0000000000000000004404 99.0
HKD2_k127_5857455_4 - - - - 0.0000008387 59.0
HKD2_k127_5857455_5 - - - - 0.000003187 59.0
HKD2_k127_5942095_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 431.0
HKD2_k127_5942095_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005867 246.0
HKD2_k127_5942095_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000003001 191.0
HKD2_k127_5942095_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000002234 177.0
HKD2_k127_5942095_4 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000004861 122.0
HKD2_k127_5942095_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000009057 82.0
HKD2_k127_5942095_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000008752 65.0
HKD2_k127_5990201_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 3.015e-196 626.0
HKD2_k127_5990201_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 397.0
HKD2_k127_5990201_2 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
HKD2_k127_6107318_0 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 491.0
HKD2_k127_6107318_1 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008386 411.0
HKD2_k127_6107318_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 378.0
HKD2_k127_6107318_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 291.0
HKD2_k127_6124909_0 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000004881 239.0
HKD2_k127_6124909_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000001874 136.0
HKD2_k127_6124909_2 PFAM glycosyl transferase family 9 K02843,K02849 - - 0.0000000000000000000000000000000006382 141.0
HKD2_k127_6125387_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 595.0
HKD2_k127_6125387_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 377.0
HKD2_k127_6125387_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0002197 53.0
HKD2_k127_6125387_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 365.0
HKD2_k127_6125387_3 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 331.0
HKD2_k127_6125387_4 lipopolysaccharide-transporting ATPase activity K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001345 271.0
HKD2_k127_6125387_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000002405 139.0
HKD2_k127_6125387_6 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000000000000000002822 128.0
HKD2_k127_6125387_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000004263 123.0
HKD2_k127_6125387_8 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000116 92.0
HKD2_k127_6125387_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00009946 53.0
HKD2_k127_6175178_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 468.0
HKD2_k127_6175178_1 usher protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005645 267.0
HKD2_k127_6175178_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.0000000000000000000000000000000000000001193 159.0
HKD2_k127_6175178_3 cellulose binding - - - 0.0000000000000000000000000002799 128.0
HKD2_k127_6175178_4 Chaperone - - - 0.0000000000000000000000001064 117.0
HKD2_k127_6215564_0 nucleotide-excision repair K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.494e-299 930.0
HKD2_k127_6215564_1 D-alanyl-D-alanine carboxypeptidase D-alanyl-D-alanine-endopeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000137 137.0
HKD2_k127_6215564_2 RNA polymerase-associated protein CTR9 homolog K15176 GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009909,GO:0009910,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016020,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0034243,GO:0034968,GO:0035327,GO:0036211,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048581,GO:0048831,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:1901564,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141,GO:2001252 - 0.00001587 58.0
HKD2_k127_6215564_3 Belongs to the ClpS family K06891 - - 0.0002916 46.0
HKD2_k127_6217579_0 protein secretion - - - 0.00000000000000000000000000000000000000000000000000000000000001166 243.0
HKD2_k127_6217579_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
HKD2_k127_6229117_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961,K01965,K01968 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 520.0
HKD2_k127_6229117_1 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
HKD2_k127_6229117_2 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000002251 172.0
HKD2_k127_6229117_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000001597 149.0
HKD2_k127_6229117_4 polysaccharide biosynthetic process - - - 0.0000000000000000000000000002347 132.0
HKD2_k127_6229117_5 Acetyl propionyl-CoA carboxylase alpha subunit K01960 - 6.4.1.1 0.000000000005034 73.0
HKD2_k127_6241571_0 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1289.0
HKD2_k127_6241571_1 BadF BadG BcrA BcrD - - - 0.0 1274.0
HKD2_k127_6241571_10 carbon-oxygen lyase activity, acting on polysaccharides K18691 - - 0.00000000000000000000000000001046 130.0
HKD2_k127_6241571_11 ComF family K00764 - 2.4.2.14 0.0000000000000000000000008451 113.0
HKD2_k127_6241571_2 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1122.0
HKD2_k127_6241571_3 ATP-binding cassette protein, ChvD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 562.0
HKD2_k127_6241571_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000002499 226.0
HKD2_k127_6241571_5 protoporphyrinogen oxidase activity K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000002632 228.0
HKD2_k127_6241571_6 lactate oxidation K16950 - - 0.0000000000000000000000000000000000000000000000000000000000108 207.0
HKD2_k127_6241571_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000009572 211.0
HKD2_k127_6241571_8 zinc ion binding K06204 - - 0.000000000000000000000000000000000000000009483 161.0
HKD2_k127_6241571_9 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000004932 150.0
HKD2_k127_6245713_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1349.0
HKD2_k127_6250195_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.688e-259 833.0
HKD2_k127_6250195_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 422.0
HKD2_k127_6250195_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 337.0
HKD2_k127_6250195_3 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.000000000000000000000000000000000000000000000000000000000000166 232.0
HKD2_k127_6250195_4 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000001126 190.0
HKD2_k127_6250195_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000001392 175.0
HKD2_k127_6250195_6 transcriptional regulator K09017 - - 0.00000000000000000000000000000000392 136.0
HKD2_k127_6250195_7 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family K18139 - - 0.0000002749 63.0
HKD2_k127_6263315_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 402.0
HKD2_k127_6263315_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
HKD2_k127_6263315_2 Belongs to the peptidase S8 family K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000006946 246.0
HKD2_k127_6263315_3 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000008201 214.0
HKD2_k127_6263315_4 endo-1,4-beta-xylanase activity K01181,K21606 - 3.2.1.202,3.2.1.8 0.00000000000000000000000917 116.0
HKD2_k127_6293812_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000007343 171.0
HKD2_k127_6293812_1 Condensation domain - - - 0.0000000000000000000000000000000000000000000004563 175.0
HKD2_k127_6293812_2 PFAM FecR protein K20276 - - 0.00000000000000000000000187 108.0
HKD2_k127_6293812_3 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000003774 103.0
HKD2_k127_6293812_4 membrane - - - 0.00000000000001464 76.0
HKD2_k127_6308815_0 ADP-dependent NAD(P)H-hydrate dehydratase activity K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 307.0
HKD2_k127_6308815_1 ribulose-phosphate 3-epimerase activity K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 262.0
HKD2_k127_6308815_2 ATP synthesis coupled electron transport K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000008291 221.0
HKD2_k127_6308815_3 VanZ like family - - - 0.00000000000306 72.0
HKD2_k127_6331800_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 4.139e-224 707.0
HKD2_k127_6331800_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 496.0
HKD2_k127_6331800_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 400.0
HKD2_k127_6331800_3 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 338.0
HKD2_k127_6331933_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 562.0
HKD2_k127_6331933_1 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 406.0
HKD2_k127_6331933_2 involved in lipopolysaccharide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 335.0
HKD2_k127_6331933_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 336.0
HKD2_k127_6331933_4 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000046 276.0
HKD2_k127_6331933_5 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000149 248.0
HKD2_k127_6331933_6 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000009549 184.0
HKD2_k127_6331933_7 Bacterial PH domain K08981 - - 0.0000000000000000000000000000000000005784 148.0
HKD2_k127_6397396_0 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 325.0
HKD2_k127_6397396_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000001402 162.0
HKD2_k127_6397396_2 regulation of single-species biofilm formation K13572 - - 0.00009693 53.0
HKD2_k127_6461282_0 ATP synthesis coupled electron transport K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000005596 198.0
HKD2_k127_6461282_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000009757 154.0
HKD2_k127_6461282_2 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000008032 141.0
HKD2_k127_6461282_3 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000002039 103.0
HKD2_k127_6461282_4 amine dehydrogenase activity - - - 0.000000000000000001417 96.0
HKD2_k127_6475622_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 293.0
HKD2_k127_6475622_1 Male sterility protein K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
HKD2_k127_6475622_2 - - - - 0.000000000000000000000000000000002939 147.0
HKD2_k127_6475622_3 Polysaccharide biosynthesis protein - - - 0.0002152 45.0
HKD2_k127_6535001_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 316.0
HKD2_k127_6535001_1 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001442 269.0
HKD2_k127_6535001_2 PFAM UvrB UvrC protein K08999 - - 0.0000000000000000000000000000000000000000000000003498 182.0
HKD2_k127_6535001_3 PFAM conserved - - - 0.0000003269 53.0
HKD2_k127_6540688_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 456.0
HKD2_k127_6540688_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
HKD2_k127_6540688_2 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 315.0
HKD2_k127_6540688_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000008431 203.0
HKD2_k127_6540688_4 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000000000000004081 113.0
HKD2_k127_6575070_0 pectinesterase activity K10297,K15923,K18197,K19615 - 3.2.1.51,4.2.2.23 0.0000000000000000000000000000000000000002915 166.0
HKD2_k127_6605876_0 Protein of unknown function (DUF1579) - - - 0.000000000000000000000000000000000000000000000000003569 187.0
HKD2_k127_6605876_1 cellulose binding - - - 0.000000000000000000000000004084 119.0
HKD2_k127_6605876_2 cellulose binding - - - 0.000000000000000000001678 96.0
HKD2_k127_6609175_0 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 527.0
HKD2_k127_6609175_1 PFAM MazG nucleotide pyrophosphohydrolase K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000003206 198.0
HKD2_k127_6609175_2 serine-type D-Ala-D-Ala carboxypeptidase activity K07259 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006508,GO:0006807,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009987,GO:0016043,GO:0016787,GO:0016998,GO:0017171,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0032505,GO:0033218,GO:0033293,GO:0036094,GO:0042597,GO:0043093,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044464,GO:0045229,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:0140096,GO:1901135,GO:1901136,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901681 3.4.16.4 0.0000000000000000000000000000269 126.0
HKD2_k127_6609175_3 NUDIX domain - - - 0.00000000000000000000004701 103.0
HKD2_k127_6609175_4 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000007743 94.0
HKD2_k127_6609175_5 xylan catabolic process K01179,K03932 - 3.2.1.4 0.0000000000000000002293 100.0
HKD2_k127_6609175_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000001861 87.0
HKD2_k127_6661597_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 429.0
HKD2_k127_6661597_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 412.0
HKD2_k127_6661597_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 384.0
HKD2_k127_6661597_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 332.0
HKD2_k127_6661597_4 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004567 269.0
HKD2_k127_6661597_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 248.0
HKD2_k127_6661597_6 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000005182 208.0
HKD2_k127_6661597_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000007882 151.0
HKD2_k127_6661597_9 Photosynthesis system II assembly factor YCF48 - - - 0.00000001771 66.0
HKD2_k127_6716830_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 382.0
HKD2_k127_6716830_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000001099 269.0
HKD2_k127_6716830_2 deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000076 243.0
HKD2_k127_6716830_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000009551 154.0
HKD2_k127_6716830_4 mitochondrial translation K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000351 114.0
HKD2_k127_6716830_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000001877 117.0
HKD2_k127_6716830_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000003857 94.0
HKD2_k127_6716830_7 Belongs to the UPF0109 family K06960 - - 0.00000000000000002702 84.0
HKD2_k127_6742677_0 Belongs to the peptidase M16 family - - - 1.12e-223 712.0
HKD2_k127_6742677_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 334.0
HKD2_k127_6742677_2 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000000002661 191.0
HKD2_k127_6760034_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K03205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 455.0
HKD2_k127_6760034_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 312.0
HKD2_k127_6779044_0 cell redox homeostasis K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 529.0
HKD2_k127_6779044_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 315.0
HKD2_k127_6797503_0 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 366.0
HKD2_k127_6797503_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 317.0
HKD2_k127_6797503_2 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
HKD2_k127_6797503_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000646 231.0
HKD2_k127_6797503_4 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000007837 218.0
HKD2_k127_6797503_5 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.00000000000000000000000000000000000000000001013 178.0
HKD2_k127_6797503_6 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000004306 143.0
HKD2_k127_6797503_7 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000009661 114.0
HKD2_k127_6804135_0 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 604.0
HKD2_k127_6804135_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000006683 117.0
HKD2_k127_6804291_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 616.0
HKD2_k127_6804291_1 cellulose binding - - - 0.00000000000001519 83.0
HKD2_k127_6804291_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0001407 48.0
HKD2_k127_6808948_0 LysM domain K08307,K12204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 344.0
HKD2_k127_6808948_1 cellulase activity - - - 0.000000000000000000000000000000000004531 146.0
HKD2_k127_6808948_2 - - - - 0.000003043 49.0
HKD2_k127_6818290_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 8.103e-231 739.0
HKD2_k127_6818290_1 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 492.0
HKD2_k127_6818290_2 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 426.0
HKD2_k127_6818290_3 XFP N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 332.0
HKD2_k127_6818290_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000001048 124.0
HKD2_k127_6818290_5 light absorption K06893 - - 0.00000000000000001499 87.0
HKD2_k127_6827356_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HKD2_k127_6827356_1 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009146 246.0
HKD2_k127_6827356_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000001876 226.0
HKD2_k127_6827356_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000002049 221.0
HKD2_k127_6827356_4 Diadenosine tetraphosphate - - - 0.00000000000000000000000000000000000000001096 157.0
HKD2_k127_6827356_5 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000001187 139.0
HKD2_k127_6846182_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 487.0
HKD2_k127_6846182_1 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 494.0
HKD2_k127_6846182_10 Belongs to the peptidase S8 family - - - 0.00000000000000000002759 106.0
HKD2_k127_6846182_11 - - - - 0.00000008625 65.0
HKD2_k127_6846182_12 Outer membrane protein Omp28 - - - 0.00008953 53.0
HKD2_k127_6846182_13 photosystem II stabilization K02237 - - 0.0005734 46.0
HKD2_k127_6846182_2 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 441.0
HKD2_k127_6846182_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 422.0
HKD2_k127_6846182_4 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 355.0
HKD2_k127_6846182_5 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 330.0
HKD2_k127_6846182_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000001173 166.0
HKD2_k127_6846182_7 cellulose binding - - - 0.000000000000000000000000000000000000001582 163.0
HKD2_k127_6846182_8 peroxiredoxin activity - - - 0.0000000000000000000000000000002291 128.0
HKD2_k127_6846182_9 endo-1,4-beta-xylanase activity K21636 - 1.1.98.6 0.0000000000000000000000000000007548 135.0
HKD2_k127_6859976_0 4 iron, 4 sulfur cluster binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 560.0
HKD2_k127_6859976_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 355.0
HKD2_k127_6859976_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000001554 143.0
HKD2_k127_6859976_3 FixH - - - 0.000000000000000000000000001513 117.0
HKD2_k127_6859976_4 COG3794 Plastocyanin - - - 0.00003535 51.0
HKD2_k127_6869526_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004563 270.0
HKD2_k127_6869526_1 cAMP biosynthetic process K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000002592 267.0
HKD2_k127_6869526_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000002023 215.0
HKD2_k127_6869526_3 Uncharacterized protein family UPF0029 - - - 0.0000000000000000000000000000000000000009777 154.0
HKD2_k127_6869526_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000002859 82.0
HKD2_k127_6923751_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.764e-259 804.0
HKD2_k127_6923751_1 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
HKD2_k127_6923751_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000004187 215.0
HKD2_k127_6923751_3 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.0000000000000005472 81.0
HKD2_k127_6930379_0 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 518.0
HKD2_k127_6930379_1 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
HKD2_k127_6930379_2 DNA-dependent ATPase I and helicase II - - - 0.00000000000000000000000000000000000002647 154.0
HKD2_k127_6930379_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000001552 129.0
HKD2_k127_6941762_0 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 334.0
HKD2_k127_6941762_1 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000003657 118.0
HKD2_k127_6941762_2 transcriptional regulator, Rrf2 family - - - 0.0000000000000000003849 91.0
HKD2_k127_6950368_0 oligopeptide transport K03305 - - 4.092e-208 655.0
HKD2_k127_6950368_1 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 510.0
HKD2_k127_6950368_2 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 458.0
HKD2_k127_6950368_3 phosphoribosylamine-glycine ligase activity K01945,K01952 - 6.3.4.13,6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 397.0
HKD2_k127_6950368_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 316.0
HKD2_k127_6950368_5 protein histidine kinase activity K02491,K13533,K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000002847 191.0
HKD2_k127_6950368_6 Serine Threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000002573 151.0
HKD2_k127_6950368_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000003922 117.0
HKD2_k127_6950368_8 phosphorelay signal transduction system K07714 - - 0.0000000000000001791 84.0
HKD2_k127_6950368_9 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.0000000000001383 72.0
HKD2_k127_6991991_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 470.0
HKD2_k127_6991991_1 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000278 265.0
HKD2_k127_6991991_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000006098 196.0
HKD2_k127_6991991_3 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000002768 191.0
HKD2_k127_6991991_4 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000008029 171.0
HKD2_k127_6991991_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000007746 100.0
HKD2_k127_7008453_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 578.0
HKD2_k127_7008453_1 - - - - 0.000000000000000000000000000000001007 134.0
HKD2_k127_7008453_2 Belongs to the peptidase S8 family K07093 - - 0.000000000000001012 87.0
HKD2_k127_7014048_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 292.0
HKD2_k127_7014048_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009309 271.0
HKD2_k127_7014048_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
HKD2_k127_7014048_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000004291 178.0
HKD2_k127_7014048_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001641 145.0
HKD2_k127_7014048_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000002362 133.0
HKD2_k127_7015096_0 lipopolysaccharide-transporting ATPase activity K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 301.0
HKD2_k127_7015096_1 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000865 266.0
HKD2_k127_7015096_2 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005089 244.0
HKD2_k127_7015096_3 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000000000000000000000000001977 149.0
HKD2_k127_7015096_4 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000000000000000000000001014 149.0
HKD2_k127_7015096_5 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000002782 109.0
HKD2_k127_7015096_6 gag-polyprotein putative aspartyl protease - - - 0.000000005262 59.0
HKD2_k127_7015096_7 Aspartyl protease - - - 0.0000001831 55.0
HKD2_k127_7059743_0 UMP kinase activity K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 330.0
HKD2_k127_7059743_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 253.0
HKD2_k127_7059743_2 cytoplasmic translational termination K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000009982 218.0
HKD2_k127_7059743_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003969 212.0
HKD2_k127_7059743_4 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000001195 149.0
HKD2_k127_7067492_0 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001172 254.0
HKD2_k127_7067492_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000001875 206.0
HKD2_k127_7067492_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000001674 140.0
HKD2_k127_7067492_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000003 87.0
HKD2_k127_7067492_4 PFAM S-layer homology domain - - - 0.0003759 49.0
HKD2_k127_7097967_0 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 337.0
HKD2_k127_7097967_1 Sugar (and other) transporter - - - 0.0000000000000000000000000003377 120.0
HKD2_k127_7174387_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000001262 231.0
HKD2_k127_7174387_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000005317 168.0
HKD2_k127_7174387_2 metallopeptidase activity - - - 0.00000000000004848 85.0
HKD2_k127_7212141_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 9.895e-207 666.0
HKD2_k127_7221737_0 Cytochrome C-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 595.0
HKD2_k127_7221737_1 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000001576 227.0
HKD2_k127_7221737_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000001161 96.0
HKD2_k127_7224537_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 311.0
HKD2_k127_7224537_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 284.0
HKD2_k127_7224537_2 peptidyl-prolyl cis-trans isomerase activity K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000003709 216.0
HKD2_k127_7224537_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000005618 196.0
HKD2_k127_7224537_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000825 139.0
HKD2_k127_7224537_6 CorA-like Mg2+ transporter protein K03284 - - 0.00002997 47.0
HKD2_k127_7228249_0 Peptidase M16C associated - - - 0.0 1026.0
HKD2_k127_7228249_1 Ion transport protein K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 375.0
HKD2_k127_7228249_10 glyoxalase K01759 - 4.4.1.5 0.0001859 46.0
HKD2_k127_7228249_11 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.0002948 47.0
HKD2_k127_7228249_2 RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 330.0
HKD2_k127_7228249_3 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 317.0
HKD2_k127_7228249_4 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 312.0
HKD2_k127_7228249_5 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 303.0
HKD2_k127_7228249_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004201 268.0
HKD2_k127_7228249_7 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
HKD2_k127_7228249_8 Endonuclease containing a URI domain K07461 - - 0.00000000000000003113 85.0
HKD2_k127_7228249_9 Endonuclease containing a URI domain K07461 - - 0.000000001931 60.0
HKD2_k127_7257637_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 4.034e-286 892.0
HKD2_k127_7257637_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 428.0
HKD2_k127_7257637_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000481 263.0
HKD2_k127_7257637_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K00939,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000005038 220.0
HKD2_k127_7257637_4 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000006186 185.0
HKD2_k127_7257637_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002905 77.0
HKD2_k127_7257637_6 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000001297 82.0
HKD2_k127_7284382_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 426.0
HKD2_k127_7284382_1 prolyl-tRNA aminoacylation K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 255.0
HKD2_k127_7284382_2 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000003099 246.0
HKD2_k127_7284382_3 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000002012 242.0
HKD2_k127_7284382_4 cobalamin binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000468 207.0
HKD2_k127_7284382_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000008352 180.0
HKD2_k127_7308053_0 oligosaccharyl transferase activity K19003,K20327 - 2.4.1.336 0.0000000000000000000000000000000000000000002319 177.0
HKD2_k127_7308053_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000004638 166.0
HKD2_k127_7308053_2 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.00000000000000000000004192 102.0
HKD2_k127_7308053_3 Domain of unknown function (DUF1736) - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.0000006041 61.0
HKD2_k127_7335072_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 302.0
HKD2_k127_7335072_1 phosphoribosylformylglycinamidine synthase activity K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 289.0
HKD2_k127_7335072_2 lipopolysaccharide-transporting ATPase activity K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007157 284.0
HKD2_k127_7335072_3 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 256.0
HKD2_k127_7335072_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000003569 220.0
HKD2_k127_7335072_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000004001 193.0
HKD2_k127_7335072_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000005035 103.0
HKD2_k127_7335072_7 protein secretion K03116,K03117 - - 0.0000000000006156 70.0
HKD2_k127_7335072_8 DNA polymerase III K02340 - 2.7.7.7 0.0001518 52.0
HKD2_k127_7343999_0 Belongs to the peptidase S1B family - - - 2.015e-232 738.0
HKD2_k127_7343999_1 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 1.43e-214 681.0
HKD2_k127_7343999_2 Belongs to the peptidase S1B family - - - 1.771e-195 625.0
HKD2_k127_7343999_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 373.0
HKD2_k127_7343999_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 355.0
HKD2_k127_7343999_5 cellulose binding - - - 0.00000000000000000000000000000000000000000000000008492 203.0
HKD2_k127_7343999_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000001478 154.0
HKD2_k127_7343999_7 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex K03589 - - 0.0005641 50.0
HKD2_k127_7373039_0 glycogen phosphorylase activity K00688,K00691 - 2.4.1.1,2.4.1.8 1.405e-217 695.0
HKD2_k127_7373039_1 NAD-dependent epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 435.0
HKD2_k127_7373039_2 Cytochrome c554 and c-prime K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 320.0
HKD2_k127_7373039_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 254.0
HKD2_k127_7373039_4 (ABC) transporter K02471,K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004946 255.0
HKD2_k127_7373039_5 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.000000000000000000000000000000000000000000000000000000000000000006512 246.0
HKD2_k127_7456029_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.132e-194 621.0
HKD2_k127_7456029_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 472.0
HKD2_k127_7456029_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 409.0
HKD2_k127_7456029_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000001285 203.0
HKD2_k127_7461427_0 Two component regulator propeller K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 552.0
HKD2_k127_7461427_1 Phenylalanine-4-hydroxylase K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 440.0
HKD2_k127_7461427_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000003533 115.0
HKD2_k127_7461427_11 response regulator K02282 - - 0.0000000000000007035 81.0
HKD2_k127_7461427_12 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000718 48.0
HKD2_k127_7461427_2 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 314.0
HKD2_k127_7461427_3 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.000000000000000000000000000000000000000000000000000000000003347 214.0
HKD2_k127_7461427_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000001566 181.0
HKD2_k127_7461427_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000001224 175.0
HKD2_k127_7461427_6 cellulose binding - - - 0.000000000000000000000000000000000000000000974 173.0
HKD2_k127_7461427_7 KR domain - - - 0.0000000000000000000000000000000000000001761 158.0
HKD2_k127_7461427_8 Aspartyl protease - - - 0.0000000000000000000000000000000002993 143.0
HKD2_k127_7461427_9 cellulose binding - - - 0.000000000000000000000000000001612 135.0
HKD2_k127_7479292_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 398.0
HKD2_k127_7479292_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001196 261.0
HKD2_k127_7479292_2 metallocarboxypeptidase activity K06987,K07752 - 3.4.17.22 0.0000000000000000000000000000000000000000001176 169.0
HKD2_k127_7483108_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 297.0
HKD2_k127_7483108_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006013 286.0
HKD2_k127_7483108_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003591 269.0
HKD2_k127_7483108_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000158 178.0
HKD2_k127_7506578_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 533.0
HKD2_k127_7506578_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 441.0
HKD2_k127_7506578_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 299.0
HKD2_k127_7506578_3 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000007781 177.0
HKD2_k127_7506578_4 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000002071 146.0
HKD2_k127_7506578_5 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000002665 100.0
HKD2_k127_7537485_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 377.0
HKD2_k127_7537485_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002597 254.0
HKD2_k127_7537485_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000003483 246.0
HKD2_k127_7537485_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000468 193.0
HKD2_k127_7537485_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000002145 98.0
HKD2_k127_7537485_5 thiolester hydrolase activity K06889 - - 0.0000000000000000007268 96.0
HKD2_k127_7552578_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 361.0
HKD2_k127_7552578_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 302.0
HKD2_k127_7552578_2 - K07283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
HKD2_k127_7552578_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001257 284.0
HKD2_k127_7603706_0 PFAM peptidase M13 K07386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 569.0
HKD2_k127_7603706_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 505.0
HKD2_k127_7617425_0 molybdopterin cofactor binding K08352 - 1.8.5.5 0.0 1121.0
HKD2_k127_7617425_1 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 327.0
HKD2_k127_7617425_2 'Molybdopterin K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 319.0
HKD2_k127_7617425_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000007121 175.0
HKD2_k127_7617425_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000009996 138.0
HKD2_k127_7626995_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 607.0
HKD2_k127_7626995_2 - - - - 0.0000007156 60.0
HKD2_k127_7704956_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 419.0
HKD2_k127_7704956_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008203 247.0
HKD2_k127_7710709_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.894e-228 732.0
HKD2_k127_7710709_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 359.0
HKD2_k127_7710709_2 3-Demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 351.0
HKD2_k127_7710709_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000006352 192.0
HKD2_k127_7710709_4 Tetratricopeptide repeat protein - - - 0.00000000000000002868 97.0
HKD2_k127_7868969_0 CoA binding domain protein K09181 - - 0.0 1063.0
HKD2_k127_7868969_1 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 576.0
HKD2_k127_7868969_10 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 304.0
HKD2_k127_7868969_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003707 254.0
HKD2_k127_7868969_12 gas vesicle protein - - - 0.00000000000000000000000000000000002645 139.0
HKD2_k127_7868969_13 Transcriptional regulator - - - 0.00000000000000000000000000008013 121.0
HKD2_k127_7868969_14 Domain of unknown function(DUF2779) - - - 0.00000000000000000000002484 108.0
HKD2_k127_7868969_15 cellulase activity K01186,K01197,K01206,K05988,K11931,K18197,K18198 - 3.2.1.11,3.2.1.18,3.2.1.35,3.2.1.51,4.2.2.23,4.2.2.24 0.00000000000000000004077 106.0
HKD2_k127_7868969_16 Belongs to the peptidase S8 family - - - 0.0000007889 50.0
HKD2_k127_7868969_17 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00005664 49.0
HKD2_k127_7868969_19 Methylamine utilisation protein MauE - - - 0.0001472 51.0
HKD2_k127_7868969_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 463.0
HKD2_k127_7868969_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 469.0
HKD2_k127_7868969_4 sulphate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 462.0
HKD2_k127_7868969_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
HKD2_k127_7868969_6 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 409.0
HKD2_k127_7868969_7 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 366.0
HKD2_k127_7868969_8 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 324.0
HKD2_k127_7868969_9 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 337.0
HKD2_k127_7918593_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 494.0
HKD2_k127_7918593_1 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000004025 203.0
HKD2_k127_7918593_2 cellulose binding - - - 0.000000000000000000000000000000000000000002648 171.0
HKD2_k127_7918593_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000001578 91.0
HKD2_k127_7926964_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1005.0
HKD2_k127_7926964_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 8e-312 971.0
HKD2_k127_7926964_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002164 244.0
HKD2_k127_7926964_11 PFAM Peroxiredoxin, OsmC-like protein - - - 0.0000000000000000000000000000000000000000000002634 170.0
HKD2_k127_7926964_12 cytoplasmic translation K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000001195 164.0
HKD2_k127_7926964_13 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000009337 116.0
HKD2_k127_7926964_14 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000121 98.0
HKD2_k127_7926964_15 Regulatory protein, FmdB family - - - 0.00000000000000000001469 96.0
HKD2_k127_7926964_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 4.779e-229 721.0
HKD2_k127_7926964_3 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 1.381e-210 659.0
HKD2_k127_7926964_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 508.0
HKD2_k127_7926964_5 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 456.0
HKD2_k127_7926964_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 360.0
HKD2_k127_7926964_7 Domain of unknown function (4846) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
HKD2_k127_7926964_8 rRNA binding K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006061 274.0
HKD2_k127_7926964_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
HKD2_k127_7930311_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 4.732e-247 771.0
HKD2_k127_7930311_1 - - - - 0.0000000000000002336 79.0
HKD2_k127_7969381_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000002938 236.0
HKD2_k127_7969381_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000004809 224.0
HKD2_k127_7969381_2 Protein of unknown function (DUF3298) - - - 0.0000000000000000000000000000000000000000000002466 175.0
HKD2_k127_7969381_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000001056 132.0
HKD2_k127_7969381_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000005186 88.0
HKD2_k127_797003_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 396.0
HKD2_k127_797003_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 390.0
HKD2_k127_797003_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 336.0
HKD2_k127_7983441_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 2.71e-265 830.0
HKD2_k127_7983441_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 454.0
HKD2_k127_7983441_2 Heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003361 253.0
HKD2_k127_7983441_3 Riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000002911 179.0
HKD2_k127_7983441_4 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000007833 176.0
HKD2_k127_7983647_0 Terminase RNAseH like domain K06909 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 323.0
HKD2_k127_7983647_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000005947 172.0
HKD2_k127_7983647_2 - - - - 0.0000000000000000000000000000000000003782 151.0
HKD2_k127_7983647_3 Protein of unknown function (DUF3298) - - - 0.0002418 49.0
HKD2_k127_7985599_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 313.0
HKD2_k127_7985599_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001493 147.0
HKD2_k127_7985599_2 cell septum assembly - - - 0.00000000000000000000004044 113.0
HKD2_k127_7985599_3 Transport permease protein K01992 - - 0.0008692 46.0
HKD2_k127_8012425_0 Superfamily I DNA and RNA K10742 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 638.0
HKD2_k127_8012425_1 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 542.0
HKD2_k127_8012425_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0002543 44.0
HKD2_k127_8012425_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 453.0
HKD2_k127_8012425_3 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 397.0
HKD2_k127_8012425_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
HKD2_k127_8012425_5 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000005827 218.0
HKD2_k127_8012425_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000000000000000000000000000008742 216.0
HKD2_k127_8012425_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000003019 199.0
HKD2_k127_8012425_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000001374 152.0
HKD2_k127_8012425_9 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000004342 115.0
HKD2_k127_8088583_0 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 306.0
HKD2_k127_8088583_1 pyrroloquinoline quinone binding K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 288.0
HKD2_k127_8088583_2 AIR carboxylase K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002204 241.0
HKD2_k127_8088583_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000002709 163.0
HKD2_k127_8092606_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 329.0
HKD2_k127_8092606_2 cellulase activity K01186,K01197,K01206,K05988,K11931,K18197,K18198 - 3.2.1.11,3.2.1.18,3.2.1.35,3.2.1.51,4.2.2.23,4.2.2.24 0.00000000000000003474 95.0
HKD2_k127_8092606_3 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000007387 59.0
HKD2_k127_8126828_0 8-amino-7-oxononanoate synthase activity K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 564.0
HKD2_k127_8126828_1 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 353.0
HKD2_k127_8126828_2 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004925 234.0
HKD2_k127_8126828_3 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000001187 201.0
HKD2_k127_8126828_4 AAA domain - - - 0.000000000000000000000000000000000000000000942 162.0
HKD2_k127_8139365_0 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 359.0
HKD2_k127_8139365_1 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 327.0
HKD2_k127_8139365_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000003237 219.0
HKD2_k127_8139365_3 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000005717 179.0
HKD2_k127_8139365_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000008484 139.0
HKD2_k127_8139365_5 efflux transmembrane transporter activity - - - 0.000000000000000007484 96.0
HKD2_k127_8164338_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 437.0
HKD2_k127_8164338_1 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004042 283.0
HKD2_k127_8164338_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003391 253.0
HKD2_k127_8164338_3 SRPBCC domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000008822 201.0
HKD2_k127_8164338_4 COG3209 Rhs family protein - - - 0.00001161 56.0
HKD2_k127_8195323_0 Two component regulator propeller K00936 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 494.0
HKD2_k127_8195323_1 Two component regulator propeller K00936 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 392.0
HKD2_k127_8195323_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000005785 194.0
HKD2_k127_8195323_3 response regulator - - - 0.00000000000008934 74.0
HKD2_k127_8199944_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 493.0
HKD2_k127_8199944_1 extracellular polysaccharide biosynthetic process K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 471.0
HKD2_k127_8199944_2 NAD-dependent epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 391.0
HKD2_k127_8199944_3 Nucleotidyl transferase K00966,K21210 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 303.0
HKD2_k127_8199944_4 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000005072 167.0
HKD2_k127_8199944_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000007926 82.0
HKD2_k127_8199944_6 polysaccharide export K01991 - - 0.0000000000000009999 85.0
HKD2_k127_8216843_0 TonB-dependent receptor - - - 0.0 1170.0
HKD2_k127_8216843_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 411.0
HKD2_k127_8216843_2 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 352.0
HKD2_k127_8216843_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
HKD2_k127_8216843_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000606 231.0
HKD2_k127_8216843_5 PD-(D/E)XK nuclease superfamily K09124 - - 0.000000000000000000000000000000000000000000000000000000000000263 214.0
HKD2_k127_8216843_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000006326 194.0
HKD2_k127_8216843_7 IMG reference gene - - - 0.00000000000000000000000004131 124.0
HKD2_k127_8237441_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 529.0
HKD2_k127_8237441_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003617 257.0
HKD2_k127_8237441_2 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000002863 223.0
HKD2_k127_8237441_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000007068 210.0
HKD2_k127_8237441_4 - - - - 0.0000000000000000000000000000000000000000000000002724 187.0
HKD2_k127_8237441_5 domain protein K01186 - 3.2.1.18 0.00000000000000000000000000000000000003193 156.0
HKD2_k127_8237441_6 chlorophyll binding K03651,K03771,K07017 - 3.1.4.53,5.2.1.8 0.000000000000000004905 95.0
HKD2_k127_8237441_8 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000002375 81.0
HKD2_k127_8248825_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 321.0
HKD2_k127_8248825_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 291.0
HKD2_k127_8248825_10 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000005756 98.0
HKD2_k127_8248825_11 Ribosomal protein L33 - - - 0.00000007512 55.0
HKD2_k127_8248825_13 DNA polymerase III K02341 - 2.7.7.7 0.0004873 46.0
HKD2_k127_8248825_2 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000008739 264.0
HKD2_k127_8248825_3 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
HKD2_k127_8248825_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000005179 205.0
HKD2_k127_8248825_5 response to copper ion K07156 - - 0.000000000000000000000000000000000000000000000000000002274 208.0
HKD2_k127_8248825_6 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000009403 166.0
HKD2_k127_8248825_7 metallopeptidase activity - - - 0.00000000000000000000000000000000000000006407 156.0
HKD2_k127_8248825_8 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000004483 140.0
HKD2_k127_8248825_9 NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000003107 128.0
HKD2_k127_8251240_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 1.082e-203 640.0
HKD2_k127_8251240_1 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 392.0
HKD2_k127_8251240_2 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000001477 209.0
HKD2_k127_8251240_3 Protein conserved in bacteria - - - 0.0000000000000004969 84.0
HKD2_k127_8269978_0 Alpha/beta hydrolase family - - - 2.601e-274 856.0
HKD2_k127_8269978_1 - - - - 0.000000000000000000000000000004183 124.0
HKD2_k127_8302306_0 PFAM Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 396.0
HKD2_k127_8302306_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000203 263.0
HKD2_k127_8302306_2 NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006064 258.0
HKD2_k127_8302306_3 ATP-dependent transcriptional regulator K03556 - - 0.0000000000000000000000000000000000000000001299 183.0
HKD2_k127_8302306_4 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000002004 122.0
HKD2_k127_8302306_5 peptidase activity, acting on L-amino acid peptides K03385 - 1.7.2.2 0.0000000000000000000001177 113.0
HKD2_k127_8302306_6 self proteolysis K04771 - 3.4.21.107 0.0000007178 51.0
HKD2_k127_8379850_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.508e-228 713.0
HKD2_k127_8379850_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000002255 160.0
HKD2_k127_8379850_2 pectinesterase activity K10297,K15923,K18197 - 3.2.1.51,4.2.2.23 0.00000000000000000000000001899 124.0
HKD2_k127_8379850_3 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000509 53.0
HKD2_k127_8395748_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 321.0
HKD2_k127_8395748_1 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000001649 208.0
HKD2_k127_8395748_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000003094 194.0
HKD2_k127_8395748_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000003251 153.0
HKD2_k127_8408591_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 403.0
HKD2_k127_8408591_1 FES K10773 - 4.2.99.18 0.000000005066 61.0
HKD2_k127_8412629_0 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 5.992e-235 738.0
HKD2_k127_8412629_1 extracellular polysaccharide biosynthetic process K16554,K16692 - - 1.048e-200 649.0
HKD2_k127_8412629_10 methenyltetrahydrofolate cyclohydrolase activity K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 354.0
HKD2_k127_8412629_11 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 322.0
HKD2_k127_8412629_12 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003226 283.0
HKD2_k127_8412629_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000001547 263.0
HKD2_k127_8412629_14 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000005043 254.0
HKD2_k127_8412629_15 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000004591 221.0
HKD2_k127_8412629_16 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000004387 148.0
HKD2_k127_8412629_17 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000001549 146.0
HKD2_k127_8412629_18 Transcription termination factor nusG K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000318 134.0
HKD2_k127_8412629_19 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000001246 126.0
HKD2_k127_8412629_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K12952 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 597.0
HKD2_k127_8412629_20 Cupin domain K11312 - - 0.000000000000000000008414 95.0
HKD2_k127_8412629_22 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000001021 57.0
HKD2_k127_8412629_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0001412 49.0
HKD2_k127_8412629_3 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 564.0
HKD2_k127_8412629_4 UDP-N-acetyl-D-mannosamine dehydrogenase activity K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 551.0
HKD2_k127_8412629_5 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 531.0
HKD2_k127_8412629_6 GDP-mannose 4,6-dehydratase activity K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 520.0
HKD2_k127_8412629_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 513.0
HKD2_k127_8412629_8 Major Facilitator Superfamily K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 450.0
HKD2_k127_8412629_9 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 366.0
HKD2_k127_8422738_0 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 568.0
HKD2_k127_8422738_1 CTP:tRNA cytidylyltransferase activity K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 554.0
HKD2_k127_8422738_10 EamA-like transporter family - - - 0.00000000000002159 84.0
HKD2_k127_8422738_11 Colicin V production protein K03558 - - 0.00000005619 61.0
HKD2_k127_8422738_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 408.0
HKD2_k127_8422738_3 negative regulation of DNA recombination K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 419.0
HKD2_k127_8422738_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 318.0
HKD2_k127_8422738_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009126 265.0
HKD2_k127_8422738_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000001334 146.0
HKD2_k127_8422738_7 protein trimerization K15368 - - 0.00000000000000000000000000001591 126.0
HKD2_k127_8422738_8 folic acid binding K00605,K06980 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0051186,GO:0071840 2.1.2.10 0.000000000000000000000000886 115.0
HKD2_k127_8422738_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000003133 88.0
HKD2_k127_8439504_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 408.0
HKD2_k127_8439504_1 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
HKD2_k127_8439504_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 300.0
HKD2_k127_8439504_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437,K15333 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.185,2.1.1.34 0.000000000000000000000000000000000000000000000000000000003116 206.0
HKD2_k127_8439504_4 - K07275 - - 0.00000000000000000000003809 107.0
HKD2_k127_8498769_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 1.036e-204 644.0
HKD2_k127_8498769_1 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000000000000001015 111.0
HKD2_k127_8498769_2 nucleotide catabolic process K05996 - 3.4.17.18 0.00000000000000000001962 102.0
HKD2_k127_8498769_3 thioesterase K07107 - - 0.00000000009155 68.0
HKD2_k127_8498769_4 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000001764 59.0
HKD2_k127_8498769_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0008789 47.0
HKD2_k127_8526471_0 Sigma-54 interaction domain K03413,K13589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 345.0
HKD2_k127_8526471_1 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
HKD2_k127_8526471_2 - - - - 0.000000000000000000000000000000000001303 153.0
HKD2_k127_8526471_3 Lipopolysaccharide-assembly - - - 0.0000000007057 66.0
HKD2_k127_8597628_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 418.0
HKD2_k127_8597628_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 382.0
HKD2_k127_8597628_10 Outer membrane efflux protein K12340 - - 0.00000000000000000000001086 115.0
HKD2_k127_8597628_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 350.0
HKD2_k127_8597628_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 351.0
HKD2_k127_8597628_4 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003021 268.0
HKD2_k127_8597628_5 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000004394 218.0
HKD2_k127_8597628_6 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.000000000000000000000000000000000000000000000000000000004141 211.0
HKD2_k127_8597628_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000004808 173.0
HKD2_k127_8597628_8 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000000000007833 164.0
HKD2_k127_8597628_9 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000009513 149.0
HKD2_k127_8632021_0 cellulose binding - - - 0.00000000000000000000000000000000000000189 168.0
HKD2_k127_8632021_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000001377 111.0
HKD2_k127_8642910_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000003571 223.0
HKD2_k127_8642910_1 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000002204 153.0
HKD2_k127_8678301_0 Dipeptidase - - - 3.448e-211 668.0
HKD2_k127_8700031_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 388.0
HKD2_k127_8700031_1 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000006918 213.0
HKD2_k127_8700031_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000002872 179.0
HKD2_k127_8700031_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000002158 123.0
HKD2_k127_8704307_0 cellulose binding - - - 4.825e-249 789.0
HKD2_k127_8704307_1 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 526.0
HKD2_k127_8704307_10 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000006063 127.0
HKD2_k127_8704307_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000002607 118.0
HKD2_k127_8704307_12 cellulose binding - - - 0.0000000000000000000000001158 116.0
HKD2_k127_8704307_13 redox-active disulfide protein 2 - - - 0.0000000000000000000005576 97.0
HKD2_k127_8704307_14 Redox-active disulfide protein - - - 0.00000000000000001638 84.0
HKD2_k127_8704307_15 - - - - 0.0000000000003789 74.0
HKD2_k127_8704307_2 Psort location CytoplasmicMembrane, score 10.00 K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 419.0
HKD2_k127_8704307_3 Methylase involved in ubiquinone menaquinone biosynthesis K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 384.0
HKD2_k127_8704307_4 membrane organization K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 317.0
HKD2_k127_8704307_5 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000002497 222.0
HKD2_k127_8704307_6 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000002339 190.0
HKD2_k127_8704307_7 - - - - 0.00000000000000000000000000000000000000002671 171.0
HKD2_k127_8704307_8 - - - - 0.0000000000000000000000000000000004104 142.0
HKD2_k127_8704307_9 cell redox homeostasis K02199,K03671 - - 0.000000000000000000000000000000009162 133.0
HKD2_k127_872168_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 469.0
HKD2_k127_872168_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000006279 181.0
HKD2_k127_872168_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) - - - 0.00000000000000000000000000000000000000000005119 168.0
HKD2_k127_872168_3 - K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000009115 130.0
HKD2_k127_872168_4 iron-sulfur cluster assembly - - - 0.000000000000000000001802 95.0
HKD2_k127_8736820_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000001287 206.0
HKD2_k127_8736820_1 - - - - 0.0000000000000000000000000000002223 141.0
HKD2_k127_8736820_2 Opacity family porin protein K07275 - - 0.00000000004158 72.0
HKD2_k127_8736820_3 - - - - 0.0000001228 61.0
HKD2_k127_8751345_0 Peptidase family M13 K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 518.0
HKD2_k127_8751345_1 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000002191 167.0
HKD2_k127_8751345_2 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 0.0000000000000000000000000000002404 131.0
HKD2_k127_8751345_3 cellulose binding - - - 0.0000000000000000000000000000003813 133.0
HKD2_k127_8751345_4 Peptidase family M13 K01415,K07386 - 3.4.24.71 0.00000001835 55.0
HKD2_k127_8886443_0 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor K00281,K00282 GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016638,GO:0016642,GO:0030312,GO:0040007,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.4.4.2 0.0 1252.0
HKD2_k127_8886443_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 567.0
HKD2_k127_8886443_10 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000005832 108.0
HKD2_k127_8886443_11 Zinc carboxypeptidase - - - 0.000000000000000000000001515 118.0
HKD2_k127_8886443_12 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000002502 112.0
HKD2_k127_8886443_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000001294 88.0
HKD2_k127_8886443_14 - - - - 0.00000000000000002659 88.0
HKD2_k127_8886443_15 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000001901 64.0
HKD2_k127_8886443_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000004758 60.0
HKD2_k127_8886443_17 nucleotide catabolic process - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000005173 65.0
HKD2_k127_8886443_2 succinyl-diaminopimelate desuccinylase activity K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 531.0
HKD2_k127_8886443_3 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 453.0
HKD2_k127_8886443_4 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 434.0
HKD2_k127_8886443_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 370.0
HKD2_k127_8886443_6 - - - - 0.0000000000000000000000000000000000000000000000000000000008049 220.0
HKD2_k127_8886443_7 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000002078 183.0
HKD2_k127_8886443_8 transcription factor binding - - - 0.000000000000000000000000000000001146 133.0
HKD2_k127_8886443_9 tetratricopeptide repeat - - - 0.000000000000000000000000000226 130.0
HKD2_k127_8921731_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 410.0
HKD2_k127_8921731_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000003569 190.0
HKD2_k127_8921731_2 protein maturation K13628 - - 0.0000000000000000000000000000000000000000000001258 170.0
HKD2_k127_8929566_0 TIGRFAM N-acetyl sugar amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 477.0
HKD2_k127_8929566_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000004759 115.0
HKD2_k127_8929566_2 PFAM glycosyl transferase group 1 - - - 0.00003354 53.0
HKD2_k127_8953161_0 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 457.0
HKD2_k127_8953161_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000007442 239.0
HKD2_k127_8953161_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000003542 219.0
HKD2_k127_8953161_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000001055 136.0
HKD2_k127_8953161_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000002529 83.0
HKD2_k127_8968317_0 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 429.0
HKD2_k127_8968317_1 - - - - 0.000000000000000000000000001058 119.0
HKD2_k127_8976606_0 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001787 269.0
HKD2_k127_8976606_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000008562 119.0
HKD2_k127_8976606_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000003204 60.0
HKD2_k127_8976606_3 - - - - 0.0001729 53.0
HKD2_k127_9021252_0 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 479.0
HKD2_k127_9021252_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 343.0
HKD2_k127_9021252_10 CAAX protease self-immunity - - - 0.000000000000000002887 95.0
HKD2_k127_9021252_2 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 350.0
HKD2_k127_9021252_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004466 285.0
HKD2_k127_9021252_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000009348 263.0
HKD2_k127_9021252_5 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000001139 242.0
HKD2_k127_9021252_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000003128 222.0
HKD2_k127_9021252_7 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000009202 217.0
HKD2_k127_9021252_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000006926 182.0
HKD2_k127_9021252_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000008664 162.0
HKD2_k127_9078915_0 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 591.0
HKD2_k127_9078915_1 hydrolase family 92 - - - 0.000000000000000000000000000004248 122.0
HKD2_k127_9080210_0 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 398.0
HKD2_k127_9080210_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003277 280.0
HKD2_k127_9080210_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000005402 132.0
HKD2_k127_9080210_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002856 127.0
HKD2_k127_9080210_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002585 114.0
HKD2_k127_9080210_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000009392 61.0
HKD2_k127_9080210_2 tRNA binding K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
HKD2_k127_9080210_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000002735 233.0
HKD2_k127_9080210_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000001332 223.0
HKD2_k127_9080210_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000005888 205.0
HKD2_k127_9080210_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000249 155.0
HKD2_k127_9080210_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001581 142.0
HKD2_k127_9080210_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000226 141.0
HKD2_k127_9080210_9 rRNA binding K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000004113 132.0
HKD2_k127_9101204_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 298.0
HKD2_k127_9101204_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000004609 227.0
HKD2_k127_9101204_2 Cold-shock protein K03704 - - 0.00000000000000000000000001284 109.0
HKD2_k127_9101204_3 endo-1,4-beta-xylanase activity K01181,K21606 - 3.2.1.202,3.2.1.8 0.0000000000000000000006143 108.0
HKD2_k127_9101204_4 COG1126 ABC-type polar amino acid transport system, ATPase component K02028,K10010 - 3.6.3.21 0.0000002 52.0
HKD2_k127_9103601_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 505.0
HKD2_k127_9103601_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001239 293.0
HKD2_k127_9103601_2 regulation of single-species biofilm formation - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.000000000000000000001602 105.0
HKD2_k127_9108351_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 524.0
HKD2_k127_9108351_1 Peptidase C1-like family K01372 - 3.4.22.40 0.00000000000000000000000000000001405 132.0
HKD2_k127_912202_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 535.0
HKD2_k127_912202_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 381.0
HKD2_k127_912202_2 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 308.0
HKD2_k127_912202_3 iron ion homeostasis K03709,K04758 - - 0.00000000000000006248 82.0
HKD2_k127_912202_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000001519 62.0
HKD2_k127_9156679_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 534.0
HKD2_k127_9156679_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 404.0
HKD2_k127_9156679_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000006811 246.0
HKD2_k127_9156679_4 Thioesterase K07107 - - 0.00000000000000000000000000000006275 128.0
HKD2_k127_9156679_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000111 118.0
HKD2_k127_9156679_6 protein conserved in bacteria - - - 0.0000000000000001258 84.0
HKD2_k127_9186715_0 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 389.0
HKD2_k127_9186715_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 389.0
HKD2_k127_9186715_2 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000003977 184.0
HKD2_k127_9202259_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003349 286.0
HKD2_k127_9202259_1 ATPase (AAA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HKD2_k127_9269394_0 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000005641 233.0
HKD2_k127_9269394_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000005903 154.0
HKD2_k127_9269394_3 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000006567 101.0
HKD2_k127_9326933_0 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 371.0
HKD2_k127_9326933_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 293.0
HKD2_k127_9326933_2 cellulose binding - - - 0.00000000009766 74.0
HKD2_k127_9332952_0 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 419.0
HKD2_k127_9332952_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
HKD2_k127_9332952_2 cell cycle K05589,K12065,K13052 - - 0.0001107 49.0
HKD2_k127_9362614_0 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 2.922e-293 906.0
HKD2_k127_9362614_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 422.0
HKD2_k127_9362614_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
HKD2_k127_9362614_3 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000001799 205.0
HKD2_k127_9362614_4 Rhomboid family - - - 0.0000000000000000000000000000000000000003965 156.0
HKD2_k127_9362614_5 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'- monophosphates containing purine bases are preferred to those containing pyrimidine bases - GO:0001558,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0030307,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040008,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045927,GO:0046434,GO:0046483,GO:0046700,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0055086,GO:0065007,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000047 123.0
HKD2_k127_9362614_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000001519 117.0
HKD2_k127_9362614_7 Putative adhesin - - - 0.0000000000000805 81.0
HKD2_k127_9362614_8 - - - - 0.0000005113 57.0
HKD2_k127_9425435_0 alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 563.0
HKD2_k127_9425435_1 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 307.0
HKD2_k127_9425435_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
HKD2_k127_9425435_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003926 264.0
HKD2_k127_9425435_4 cellulose binding - - - 0.000000000000000000000000000000000808 151.0
HKD2_k127_9425435_5 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000002248 141.0
HKD2_k127_9425435_6 cellulose binding - - - 0.000000000000000000000000000000227 141.0
HKD2_k127_9425435_7 cellulose binding - - - 0.00000000000000000000000000002581 137.0
HKD2_k127_9425435_8 - - - - 0.00000000002117 73.0
HKD2_k127_9445108_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 469.0
HKD2_k127_9445108_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 396.0
HKD2_k127_9445108_2 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 306.0
HKD2_k127_9445108_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000005223 202.0
HKD2_k127_9445108_4 - - - - 0.00000000000000000000000005182 119.0
HKD2_k127_9445108_5 Peptidogalycan biosysnthesis/recognition K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 0.000001627 52.0
HKD2_k127_9475421_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 478.0
HKD2_k127_9475421_1 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
HKD2_k127_9475421_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004421 273.0
HKD2_k127_9475421_3 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000958 248.0
HKD2_k127_9475421_4 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
HKD2_k127_9475421_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001691 196.0
HKD2_k127_9475421_6 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000001764 205.0
HKD2_k127_9494969_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
HKD2_k127_9494969_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009878 277.0
HKD2_k127_9494969_2 - K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002921 244.0
HKD2_k127_9494969_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000001478 183.0
HKD2_k127_9494969_4 BNR Asp-box repeat - - - 0.0000000000000000000000000000000000002913 149.0
HKD2_k127_9495563_0 iron-sulfur cluster assembly K00123,K00184,K00335,K00336,K18006,K18332 - 1.12.1.2,1.12.1.3,1.17.1.9,1.6.5.3 0.0 1107.0
HKD2_k127_9495563_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 4.083e-216 675.0
HKD2_k127_9495563_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000004984 214.0
HKD2_k127_9495563_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000001377 66.0
HKD2_k127_9503659_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000007143 248.0
HKD2_k127_9503659_1 COG494 NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair General function prediction only K01515 - 3.6.1.13 0.000000000000000000000000000000002235 135.0
HKD2_k127_9523478_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1441.0
HKD2_k127_95373_0 Subtilase family - - - 0.000000000000000000000000000000000000006422 164.0
HKD2_k127_95373_1 metallopeptidase activity - - - 0.000000000000000000000001173 115.0
HKD2_k127_95373_2 beta-galactosidase activity - - - 0.0000000000000006345 91.0
HKD2_k127_95373_3 Sugar-specific transcriptional regulator TrmB - - - 0.00000000001941 74.0
HKD2_k127_957106_0 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000001202 158.0
HKD2_k127_957106_1 Endonuclease I - - - 0.0000000000000000000000000000000000000003894 165.0
HKD2_k127_957106_2 ATP-binding protein K06958 - - 0.000000000000000000000000000000000000006082 149.0
HKD2_k127_957106_3 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000085 121.0
HKD2_k127_9601575_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 8.787e-252 786.0
HKD2_k127_9601575_1 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 3.868e-217 683.0
HKD2_k127_9601575_2 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000004127 234.0
HKD2_k127_9601575_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000001571 194.0
HKD2_k127_9601575_4 PASTA K01921,K03587,K08884,K12132 - 2.7.11.1,3.4.16.4,6.3.2.4 0.0000000000000000000000000000000000007513 151.0
HKD2_k127_9601575_5 regulation of translation K03530,K05788 - - 0.000000000000000006975 87.0
HKD2_k127_9601575_6 chaperone-mediated protein folding K09809,K20543 - 2.7.8.12 0.00000000000001378 84.0
HKD2_k127_9601575_7 - - - - 0.0000006155 51.0
HKD2_k127_9601575_8 denitrification pathway K15876 GO:0005575,GO:0006807,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 0.0002798 43.0
HKD2_k127_9609934_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 540.0
HKD2_k127_9609934_1 Bacterial capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 364.0
HKD2_k127_9609934_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0032991,GO:0032993,GO:0043565,GO:0097159,GO:1901363 3.4.21.88 0.000000000000000000000000000000000000000238 156.0
HKD2_k127_9609934_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000003684 66.0
HKD2_k127_9609934_4 PFAM conserved - - - 0.000000009909 60.0
HKD2_k127_9636920_0 valine-tRNA ligase activity K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.202e-249 788.0
HKD2_k127_9636920_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 326.0
HKD2_k127_9636920_10 rRNA processing K07056 - 2.1.1.198 0.00000000000000000000000000000000000003176 149.0
HKD2_k127_9636920_11 Belongs to the peptidase S8 family - - - 0.00000000000000000000001466 109.0
HKD2_k127_9636920_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 322.0
HKD2_k127_9636920_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003801 265.0
HKD2_k127_9636920_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005826 253.0
HKD2_k127_9636920_5 radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000001314 220.0
HKD2_k127_9636920_6 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000001026 215.0
HKD2_k127_9636920_7 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000001787 199.0
HKD2_k127_9636920_8 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000002051 163.0
HKD2_k127_9636920_9 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000001386 161.0
HKD2_k127_96860_0 Pfam:KaiC K08482 - - 1.086e-207 661.0
HKD2_k127_96860_1 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 338.0
HKD2_k127_96860_10 - - - - 0.00000000000000000000000000006206 123.0
HKD2_k127_96860_11 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000003728 129.0
HKD2_k127_96860_13 gas vesicle protein - - - 0.00000000003363 68.0
HKD2_k127_96860_14 LysE type translocator - - - 0.000000003563 66.0
HKD2_k127_96860_15 - - - - 0.0000006188 53.0
HKD2_k127_96860_2 Chalcone and stilbene synthases, N-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 326.0
HKD2_k127_96860_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 292.0
HKD2_k127_96860_4 ATPase activity K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002319 258.0
HKD2_k127_96860_5 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000005472 197.0
HKD2_k127_96860_6 protein conserved in bacteria K16168 - - 0.000000000000000000000000000000000000000000009854 167.0
HKD2_k127_96860_7 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000178 163.0
HKD2_k127_96860_8 response regulator K07782 - - 0.0000000000000000000000000000000000000000005453 166.0
HKD2_k127_96860_9 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000000009052 157.0
HKD2_k127_9711965_0 Hemerythrin HHE cation binding domain protein K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 491.0
HKD2_k127_9711965_1 conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000000004011 160.0
HKD2_k127_9711965_2 - - - - 0.0000000000000000000003251 108.0
HKD2_k127_9737513_0 isobutyryl-CoA mutase activity K07588 GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 475.0
HKD2_k127_9737513_1 cobalamin binding K01847,K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 329.0
HKD2_k127_9737513_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006262 268.0
HKD2_k127_9737513_3 Protein of unknown function (DUF4199) - - - 0.00000000000000000000000000000000000000000000000000001714 192.0
HKD2_k127_9737513_4 - - - - 0.000002971 55.0
HKD2_k127_9751147_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
HKD2_k127_9751147_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000002855 199.0
HKD2_k127_9751147_2 PFAM nucleic acid binding, OB-fold, tRNA K01174 - 3.1.31.1 0.00000000001714 68.0
HKD2_k127_9756249_0 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 372.0
HKD2_k127_9786241_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000264 206.0
HKD2_k127_9786241_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000003783 118.0
HKD2_k127_9824462_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 589.0
HKD2_k127_9824462_1 Cytochrome b(N-terminal)/b6/petB K00412 - - 0.000000000000000000000000000000000000000000001067 174.0
HKD2_k127_9824462_2 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.000000000000000000000000000000000000103 147.0
HKD2_k127_9841612_0 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.000000000000000000000000000000000000000000000000000000574 200.0
HKD2_k127_9841612_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000004383 117.0
HKD2_k127_9940251_0 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 360.0
HKD2_k127_9940251_1 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
HKD2_k127_9940251_2 WbqC-like protein family - - - 0.0000000000000000000000000000000000000002118 158.0
HKD2_k127_9940251_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004831 128.0
HKD2_k127_9940251_4 - - - - 0.0000001202 63.0
HKD2_k127_9941726_0 GMP synthase (glutamine-hydrolyzing) activity K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 1.568e-202 643.0
HKD2_k127_9941726_1 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 361.0
HKD2_k127_9941726_10 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000003918 105.0
HKD2_k127_9941726_11 Protein of unknown function (DUF2752) - - - 0.000000000000000000008401 96.0
HKD2_k127_9941726_12 TM2 domain - - - 0.0000000004698 64.0
HKD2_k127_9941726_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 289.0
HKD2_k127_9941726_3 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HKD2_k127_9941726_6 positive regulation of growth rate - - - 0.000000000000000000000000000002091 132.0
HKD2_k127_9941726_7 positive regulation of growth rate - - - 0.0000000000000000000000000001004 126.0
HKD2_k127_9941726_9 - - - - 0.0000000000000000000000196 104.0
HKD2_k127_9950981_0 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 463.0
HKD2_k127_9969584_0 protein histidine kinase activity K03413,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 573.0
HKD2_k127_9969584_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 399.0
HKD2_k127_9969584_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
HKD2_k127_9969584_3 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000009426 183.0
HKD2_k127_9969584_4 iron-sulfur cluster assembly K02482 - 2.7.13.3 0.00000000000000000007511 89.0