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Overview

ID MAG01819
Name HKD2_bin.77
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Sulfomarinibacteraceae
Genus FEB-10
Species
Assembly information
Completeness (%) 79.91
Contamination (%) 0.4
GC content (%) 71.0
N50 (bp) 31,139
Genome size (bp) 3,010,473

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2320

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10039247_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 609.0
HKD2_k127_10039247_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 517.0
HKD2_k127_10039247_10 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 338.0
HKD2_k127_10039247_11 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 298.0
HKD2_k127_10039247_12 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002281 273.0
HKD2_k127_10039247_13 CBS domain - - - 0.00000000000000000000000000000000000000000000000000005931 204.0
HKD2_k127_10039247_14 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000001397 194.0
HKD2_k127_10039247_15 Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000003742 184.0
HKD2_k127_10039247_16 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000001816 183.0
HKD2_k127_10039247_17 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000407 182.0
HKD2_k127_10039247_18 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000005776 167.0
HKD2_k127_10039247_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000003136 145.0
HKD2_k127_10039247_2 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 505.0
HKD2_k127_10039247_20 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000003121 134.0
HKD2_k127_10039247_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000005092 116.0
HKD2_k127_10039247_22 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000933 115.0
HKD2_k127_10039247_23 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.000000000000000000000001627 109.0
HKD2_k127_10039247_24 Alpha beta hydrolase - - - 0.00000000000000000000000395 114.0
HKD2_k127_10039247_25 Domain of unknown function (DUF4136) - - - 0.000000000000000000000558 105.0
HKD2_k127_10039247_26 Ndr family K01055 - 3.1.1.24 0.000000000000000000001512 110.0
HKD2_k127_10039247_27 Ndr family - - - 0.000000000000000000002503 106.0
HKD2_k127_10039247_28 PDZ domain - - - 0.000000000000000002075 96.0
HKD2_k127_10039247_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000001735 97.0
HKD2_k127_10039247_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 455.0
HKD2_k127_10039247_30 Domain of unknown function (DUF4136) - - - 0.00000000000000002615 93.0
HKD2_k127_10039247_31 Domain of unknown function (DUF4136) - - - 0.00000000000000009053 87.0
HKD2_k127_10039247_32 - - - - 0.00000000000005673 84.0
HKD2_k127_10039247_33 - - - - 0.0000000001049 72.0
HKD2_k127_10039247_34 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000005772 69.0
HKD2_k127_10039247_35 Surface antigen - - - 0.0001034 52.0
HKD2_k127_10039247_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 452.0
HKD2_k127_10039247_5 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 441.0
HKD2_k127_10039247_6 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 410.0
HKD2_k127_10039247_7 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 377.0
HKD2_k127_10039247_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 352.0
HKD2_k127_10039247_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 336.0
HKD2_k127_10048764_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 391.0
HKD2_k127_10048764_1 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000000000000000000000000000000000000001645 236.0
HKD2_k127_10048764_2 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000008997 215.0
HKD2_k127_10048764_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000002059 180.0
HKD2_k127_10048764_4 outer membrane efflux protein - - - 0.000000000000000000000000000000004558 144.0
HKD2_k127_10048764_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000009461 89.0
HKD2_k127_10048764_6 Protein of unknown function, DUF481 K07283 - - 0.00000000000000001692 98.0
HKD2_k127_10048764_7 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000008204 83.0
HKD2_k127_10048764_8 bacterioferritin comigratory protein K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000009034 57.0
HKD2_k127_1276074_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 6.459e-318 1001.0
HKD2_k127_1276074_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 7.99e-288 911.0
HKD2_k127_1276074_10 Alpha galactosidase A K07407 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0006080,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0051069,GO:0051682,GO:0071704,GO:1901575 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 610.0
HKD2_k127_1276074_11 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose K16212 - 2.4.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 595.0
HKD2_k127_1276074_12 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 582.0
HKD2_k127_1276074_13 carbohydrate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 569.0
HKD2_k127_1276074_14 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 477.0
HKD2_k127_1276074_15 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 444.0
HKD2_k127_1276074_16 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 435.0
HKD2_k127_1276074_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 422.0
HKD2_k127_1276074_18 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 388.0
HKD2_k127_1276074_19 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 363.0
HKD2_k127_1276074_2 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.936e-269 878.0
HKD2_k127_1276074_20 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 338.0
HKD2_k127_1276074_21 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 333.0
HKD2_k127_1276074_22 Domain of unknown function (DUF4861) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 336.0
HKD2_k127_1276074_23 Transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 332.0
HKD2_k127_1276074_24 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 332.0
HKD2_k127_1276074_25 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 268.0
HKD2_k127_1276074_26 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000001638 260.0
HKD2_k127_1276074_27 PFAM Binding-protein-dependent transport system inner membrane component K17246 - - 0.00000000000000000000000000000000000000000000000000000004496 210.0
HKD2_k127_1276074_28 Virulence activator alpha C-term - - - 0.00000000000000000000000003674 116.0
HKD2_k127_1276074_29 Subtilase family - - - 0.00000000000000000001241 108.0
HKD2_k127_1276074_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.326e-258 809.0
HKD2_k127_1276074_30 Outer membrane receptor - - - 0.000000000000000003174 99.0
HKD2_k127_1276074_31 - - - - 0.00000000000000034 91.0
HKD2_k127_1276074_32 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002549 72.0
HKD2_k127_1276074_4 Sodium:solute symporter family - - - 3.801e-226 724.0
HKD2_k127_1276074_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 1.834e-224 708.0
HKD2_k127_1276074_6 coagulation factor 5 8 type - - - 3.108e-218 718.0
HKD2_k127_1276074_7 Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 1.454e-213 684.0
HKD2_k127_1276074_8 9-O-acetylesterase K05970 - 3.1.1.53 1.409e-209 669.0
HKD2_k127_1276074_9 Outer membrane receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 646.0
HKD2_k127_1329648_0 TonB dependent receptor K02014 - - 1.222e-226 726.0
HKD2_k127_1329648_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 353.0
HKD2_k127_1329648_2 Purine nucleoside phosphorylase deoD-type K03784 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 323.0
HKD2_k127_1329648_3 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000006342 187.0
HKD2_k127_1329648_4 CYTH - - - 0.0000000000000000000000000000000000000000000006026 186.0
HKD2_k127_1329648_5 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000005017 155.0
HKD2_k127_1329648_6 GMC oxidoreductase - - - 0.000000002038 59.0
HKD2_k127_1338198_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 405.0
HKD2_k127_1338198_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 396.0
HKD2_k127_1338198_2 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 379.0
HKD2_k127_1338198_3 - - - - 0.000000000000008399 85.0
HKD2_k127_1359600_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 8.748e-272 869.0
HKD2_k127_1359600_1 Aminotransferase K00812 - 2.6.1.1 8.175e-198 623.0
HKD2_k127_1359600_2 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000003357 126.0
HKD2_k127_1407675_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 469.0
HKD2_k127_1407675_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000502 257.0
HKD2_k127_1409257_0 Belongs to the GPI family K01810 - 5.3.1.9 3.271e-219 700.0
HKD2_k127_1409257_1 synthase K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 443.0
HKD2_k127_1409257_10 arylsulfatase activity K01133 - 3.1.6.6 0.00000000000000000000000000000000000000009087 173.0
HKD2_k127_1409257_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000002127 163.0
HKD2_k127_1409257_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000006802 138.0
HKD2_k127_1409257_13 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000004696 147.0
HKD2_k127_1409257_14 - - - - 0.00000000000000000000000000002443 126.0
HKD2_k127_1409257_15 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000124 118.0
HKD2_k127_1409257_16 serine threonine protein kinase K12132 - 2.7.11.1 0.00000004928 66.0
HKD2_k127_1409257_18 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00009207 55.0
HKD2_k127_1409257_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 431.0
HKD2_k127_1409257_3 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 415.0
HKD2_k127_1409257_4 Belongs to the peptidase S8 family K13276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 359.0
HKD2_k127_1409257_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007351 288.0
HKD2_k127_1409257_6 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005183 269.0
HKD2_k127_1409257_7 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000001114 207.0
HKD2_k127_1409257_8 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000002902 202.0
HKD2_k127_1409257_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000564 169.0
HKD2_k127_142532_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 247.0
HKD2_k127_142532_1 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000009661 208.0
HKD2_k127_142532_2 enzyme of the cupin superfamily K06995 - - 0.00000000000000000000000000000000000000002046 154.0
HKD2_k127_142532_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 0.00000000000000000002448 96.0
HKD2_k127_1439417_0 Prokaryotic cytochrome b561 - - - 1.71e-310 983.0
HKD2_k127_1439417_1 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 7.969e-225 719.0
HKD2_k127_1439417_10 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 349.0
HKD2_k127_1439417_11 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 358.0
HKD2_k127_1439417_12 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 292.0
HKD2_k127_1439417_13 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008893 288.0
HKD2_k127_1439417_14 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001557 283.0
HKD2_k127_1439417_15 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004174 284.0
HKD2_k127_1439417_16 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD2_k127_1439417_17 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004452 260.0
HKD2_k127_1439417_18 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000003259 245.0
HKD2_k127_1439417_19 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000002414 220.0
HKD2_k127_1439417_2 Carbon starvation protein CstA K06200 - - 1.367e-214 682.0
HKD2_k127_1439417_20 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000002886 187.0
HKD2_k127_1439417_21 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000271 157.0
HKD2_k127_1439417_22 Carbon starvation protein K06200 - - 0.00000000000000000000000007999 110.0
HKD2_k127_1439417_23 Lysin motif - - - 0.0000000000000000001514 96.0
HKD2_k127_1439417_24 Wd-40 repeat - - - 0.00001342 58.0
HKD2_k127_1439417_25 LVIVD repeat-containing protein - - - 0.00005358 56.0
HKD2_k127_1439417_26 Twin-arginine translocation pathway signal protein - - - 0.0001597 52.0
HKD2_k127_1439417_27 Thioredoxin-like - - - 0.0001796 50.0
HKD2_k127_1439417_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.777e-203 653.0
HKD2_k127_1439417_4 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 542.0
HKD2_k127_1439417_5 isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 503.0
HKD2_k127_1439417_6 - K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 462.0
HKD2_k127_1439417_7 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 448.0
HKD2_k127_1439417_8 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 399.0
HKD2_k127_1439417_9 PFAM glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 352.0
HKD2_k127_1471956_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002788 236.0
HKD2_k127_1471956_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000001252 233.0
HKD2_k127_1471956_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000002636 223.0
HKD2_k127_1471956_3 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000000000121 199.0
HKD2_k127_1471956_4 TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000455 150.0
HKD2_k127_1471956_5 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0033554,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0050896,GO:0051716,GO:0071704,GO:0090407,GO:1901576 5.3.3.2 0.0000000000000000000002054 98.0
HKD2_k127_1471956_6 - - - - 0.000004031 55.0
HKD2_k127_1476556_0 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0 1605.0
HKD2_k127_1476556_1 PFAM Type II secretion system protein E K02652 - - 4.072e-214 677.0
HKD2_k127_1476556_10 general secretion pathway protein K02456 - - 0.00000000000000000000000000007617 123.0
HKD2_k127_1476556_11 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000001446 117.0
HKD2_k127_1476556_12 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000009564 102.0
HKD2_k127_1476556_13 general secretion pathway protein K02456,K02650 - - 0.000000000000001128 89.0
HKD2_k127_1476556_14 Contains selenocysteine K07401 - - 0.00000000000002322 74.0
HKD2_k127_1476556_15 Protein of unknown function (DUF3011) - - - 0.000000002654 68.0
HKD2_k127_1476556_16 Pilus assembly protein, PilO K02664 - - 0.0000002148 62.0
HKD2_k127_1476556_17 PFAM Fimbrial assembly family protein K02663 - - 0.000004625 59.0
HKD2_k127_1476556_18 Pilus assembly protein K02662 - - 0.00004402 57.0
HKD2_k127_1476556_19 AntiSigma factor K03088 - - 0.000184 51.0
HKD2_k127_1476556_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 435.0
HKD2_k127_1476556_3 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006586 286.0
HKD2_k127_1476556_4 Belongs to the GSP D family K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000192 300.0
HKD2_k127_1476556_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000002056 206.0
HKD2_k127_1476556_6 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000000000000000002276 199.0
HKD2_k127_1476556_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000002697 184.0
HKD2_k127_1476556_8 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000008169 170.0
HKD2_k127_1476556_9 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000002116 179.0
HKD2_k127_1542208_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1053.0
HKD2_k127_1542208_1 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 567.0
HKD2_k127_1542208_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 329.0
HKD2_k127_1542208_3 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000002922 72.0
HKD2_k127_1589074_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 379.0
HKD2_k127_1589074_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 366.0
HKD2_k127_1589074_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 265.0
HKD2_k127_1589074_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003742 213.0
HKD2_k127_1589074_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000003439 179.0
HKD2_k127_1589074_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000000001104 91.0
HKD2_k127_1589074_7 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0001167 48.0
HKD2_k127_1595753_0 Aromatic amino acid lyase K01745 - 4.3.1.3 6.232e-218 688.0
HKD2_k127_1595753_1 Chromate transporter K07240 - - 3.939e-213 670.0
HKD2_k127_1595753_10 - - - - 0.00000000000000000000000001055 113.0
HKD2_k127_1595753_11 LVIVD repeat - - - 0.0000000000000000000000000138 122.0
HKD2_k127_1595753_12 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000007699 106.0
HKD2_k127_1595753_13 PD-(D/E)XK nuclease superfamily - - - 0.0000000007448 61.0
HKD2_k127_1595753_14 PFAM sigma-70 region 2 domain protein K03088 - - 0.000002514 57.0
HKD2_k127_1595753_2 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 434.0
HKD2_k127_1595753_3 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 408.0
HKD2_k127_1595753_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 309.0
HKD2_k127_1595753_5 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 287.0
HKD2_k127_1595753_6 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.0000000000000000000000000000000000000000000000000000000000000000122 247.0
HKD2_k127_1595753_7 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000007093 176.0
HKD2_k127_1595753_8 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000105 157.0
HKD2_k127_1595753_9 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000003501 129.0
HKD2_k127_1615073_0 ABC transporter K15738 - - 1.157e-271 838.0
HKD2_k127_1615073_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000007734 250.0
HKD2_k127_1622710_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 506.0
HKD2_k127_1622710_1 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 404.0
HKD2_k127_1622710_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 298.0
HKD2_k127_1622710_3 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000004492 138.0
HKD2_k127_1622710_4 Septum formation initiator K04074 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000003376 68.0
HKD2_k127_1622710_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000003161 54.0
HKD2_k127_1650219_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 8.836e-241 752.0
HKD2_k127_1650219_1 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 636.0
HKD2_k127_1650219_10 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000007162 98.0
HKD2_k127_1650219_11 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000003765 83.0
HKD2_k127_1650219_12 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000008398 74.0
HKD2_k127_1650219_13 Polymer-forming cytoskeletal - - - 0.00004831 55.0
HKD2_k127_1650219_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 523.0
HKD2_k127_1650219_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 344.0
HKD2_k127_1650219_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 324.0
HKD2_k127_1650219_5 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 292.0
HKD2_k127_1650219_6 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000003427 200.0
HKD2_k127_1650219_7 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000004409 154.0
HKD2_k127_1650219_8 oxidoreductase activity - - - 0.0000000000000000005039 102.0
HKD2_k127_1650219_9 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000003174 85.0
HKD2_k127_1661167_0 C4-dicarboxylate anaerobic carrier - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 542.0
HKD2_k127_1661167_1 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000001296 223.0
HKD2_k127_1661167_2 Peptidase family S51 K13282 - 3.4.15.6 0.0000000000000000000000000000000000000000000002556 179.0
HKD2_k127_1661167_3 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000001269 154.0
HKD2_k127_1661167_4 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0003042 51.0
HKD2_k127_1680598_0 DNA topoisomerase K02622 - - 1.87e-244 772.0
HKD2_k127_1680598_1 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 612.0
HKD2_k127_1680598_10 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000003785 234.0
HKD2_k127_1680598_11 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000004688 209.0
HKD2_k127_1680598_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000001176 199.0
HKD2_k127_1680598_13 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000003835 193.0
HKD2_k127_1680598_14 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000005997 210.0
HKD2_k127_1680598_15 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000002898 182.0
HKD2_k127_1680598_16 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001814 156.0
HKD2_k127_1680598_17 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000008534 150.0
HKD2_k127_1680598_18 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000000134 144.0
HKD2_k127_1680598_19 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000002219 138.0
HKD2_k127_1680598_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 528.0
HKD2_k127_1680598_20 spore germination - - - 0.000000000000000000000000000000244 137.0
HKD2_k127_1680598_21 GYD domain - - - 0.000000000000000000000000000001422 123.0
HKD2_k127_1680598_22 PFAM Peptidase M23 - - - 0.000000000000000000000000004002 123.0
HKD2_k127_1680598_23 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.000000000000000000002573 105.0
HKD2_k127_1680598_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000004511 70.0
HKD2_k127_1680598_25 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000001078 61.0
HKD2_k127_1680598_26 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000672 56.0
HKD2_k127_1680598_3 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 456.0
HKD2_k127_1680598_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 391.0
HKD2_k127_1680598_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 390.0
HKD2_k127_1680598_6 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
HKD2_k127_1680598_7 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 319.0
HKD2_k127_1680598_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 300.0
HKD2_k127_1680598_9 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000139 243.0
HKD2_k127_171790_0 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000008759 218.0
HKD2_k127_171790_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000008172 124.0
HKD2_k127_1833355_0 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 501.0
HKD2_k127_1833355_1 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 463.0
HKD2_k127_1833355_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000006566 245.0
HKD2_k127_1833355_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000007639 192.0
HKD2_k127_1833355_4 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000000000000000000005414 193.0
HKD2_k127_1833355_5 Cytochrome oxidase assembly protein K02259,K03110 - - 0.0000000000000000000000000000000001727 148.0
HKD2_k127_1833355_6 Belongs to the peptidase S8 family K13276,K17734 - - 0.00000000000000000000007652 116.0
HKD2_k127_1833355_7 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000001249 66.0
HKD2_k127_1958405_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 536.0
HKD2_k127_1958405_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 501.0
HKD2_k127_1958405_10 - - - - 0.000000000000000000000000000000000000000004972 173.0
HKD2_k127_1958405_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000004284 136.0
HKD2_k127_1958405_12 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000001648 114.0
HKD2_k127_1958405_13 isochorismatase - - - 0.00000000000000000000003515 114.0
HKD2_k127_1958405_14 Protein conserved in bacteria - - - 0.000000000000000001589 100.0
HKD2_k127_1958405_15 - - - - 0.00000000000000153 83.0
HKD2_k127_1958405_16 helix_turn_helix, mercury resistance - - - 0.000243 52.0
HKD2_k127_1958405_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 437.0
HKD2_k127_1958405_3 homocysteine catabolic process K01372,K02316 - 3.4.22.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 381.0
HKD2_k127_1958405_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 351.0
HKD2_k127_1958405_5 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 295.0
HKD2_k127_1958405_6 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001386 304.0
HKD2_k127_1958405_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001286 251.0
HKD2_k127_1958405_8 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000003927 219.0
HKD2_k127_1958405_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000001266 196.0
HKD2_k127_2073738_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 455.0
HKD2_k127_2073738_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 341.0
HKD2_k127_2073738_10 UPF0761 membrane protein K07058 - - 0.00000000000000000005756 104.0
HKD2_k127_2073738_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001066 70.0
HKD2_k127_2073738_12 Type IV Pilus-assembly protein W K02672 - - 0.00002915 57.0
HKD2_k127_2073738_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 290.0
HKD2_k127_2073738_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003649 267.0
HKD2_k127_2073738_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000002308 179.0
HKD2_k127_2073738_5 NHL repeat K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000002948 200.0
HKD2_k127_2073738_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000133 174.0
HKD2_k127_2073738_7 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000001703 185.0
HKD2_k127_2073738_8 mitochondrial genome maintenance K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002812 143.0
HKD2_k127_2073738_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000001314 134.0
HKD2_k127_2093219_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 2254.0
HKD2_k127_2093219_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 474.0
HKD2_k127_2093219_2 Restriction endonuclease, S K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000005899 215.0
HKD2_k127_2093219_4 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000002035 90.0
HKD2_k127_2093219_5 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.000000000000000007107 88.0
HKD2_k127_2093219_7 COG0286 Type I restriction-modification system methyltransferase subunit K03427 - 2.1.1.72 0.00000000000000128 87.0
HKD2_k127_2093219_8 type I restriction modification DNA specificity domain K01154,K03427 - 2.1.1.72,3.1.21.3 0.00000000305 68.0
HKD2_k127_2125149_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 311.0
HKD2_k127_2125149_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 303.0
HKD2_k127_2197381_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1023.0
HKD2_k127_2197381_1 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000002389 180.0
HKD2_k127_2197381_2 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000001374 147.0
HKD2_k127_2197381_3 Protein of unknown function (DUF2892) - - - 0.00000000000000000000005909 100.0
HKD2_k127_2197381_4 Peptidase M56 - - - 0.00000000000297 79.0
HKD2_k127_2234432_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 619.0
HKD2_k127_2234432_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 457.0
HKD2_k127_2234432_2 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006753 289.0
HKD2_k127_2234432_3 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000002681 230.0
HKD2_k127_2234432_4 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000695 224.0
HKD2_k127_2234432_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000001183 206.0
HKD2_k127_2234432_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000004176 156.0
HKD2_k127_2234432_7 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000002183 147.0
HKD2_k127_2234432_8 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000004111 92.0
HKD2_k127_2234432_9 Domain of unknown function (DUF4177) - - - 0.000607 47.0
HKD2_k127_2236431_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000007572 241.0
HKD2_k127_2236431_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000003926 173.0
HKD2_k127_2236431_2 Guanosine polyphosphate pyrophosphohydrolases synthetases - - - 0.0000000000000000000000001356 115.0
HKD2_k127_2236431_3 PhoQ Sensor - - - 0.0000000000000000000000001553 109.0
HKD2_k127_2236431_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000001507 114.0
HKD2_k127_2236431_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000004591 85.0
HKD2_k127_2265769_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 372.0
HKD2_k127_2265769_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 310.0
HKD2_k127_2265769_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 308.0
HKD2_k127_2265769_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 294.0
HKD2_k127_2265769_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001757 290.0
HKD2_k127_2265769_5 Wzt C-terminal domain K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005216 265.0
HKD2_k127_2265769_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000001344 213.0
HKD2_k127_2265769_7 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000001258 122.0
HKD2_k127_2265769_8 domain, Protein - - - 0.00002996 53.0
HKD2_k127_2265769_9 PFAM Tetratricopeptide repeat - - - 0.0001011 54.0
HKD2_k127_2375291_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.888e-272 865.0
HKD2_k127_2375291_1 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.355e-235 746.0
HKD2_k127_2375291_10 Modulates RecA activity K03565 - - 0.000000001795 67.0
HKD2_k127_2375291_11 cellulase activity - - - 0.000003056 61.0
HKD2_k127_2375291_2 Cytochrome c554 and c-prime - - - 4.827e-196 621.0
HKD2_k127_2375291_3 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 603.0
HKD2_k127_2375291_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 582.0
HKD2_k127_2375291_5 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 565.0
HKD2_k127_2375291_6 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000001146 181.0
HKD2_k127_2375291_7 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000001229 109.0
HKD2_k127_2375291_8 Fungalysin metallopeptidase (M36) - - - 0.00000000000000002187 98.0
HKD2_k127_2375291_9 cellulase activity - - - 0.0000000000004283 84.0
HKD2_k127_2444687_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 327.0
HKD2_k127_247855_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 392.0
HKD2_k127_247855_1 PFAM ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 309.0
HKD2_k127_247855_10 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000009045 106.0
HKD2_k127_247855_11 Belongs to the HesB IscA family K13628 - - 0.00000000000000000002422 96.0
HKD2_k127_247855_12 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000002386 94.0
HKD2_k127_247855_13 O-Antigen ligase - - - 0.00006713 55.0
HKD2_k127_247855_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0001495 54.0
HKD2_k127_247855_2 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003653 257.0
HKD2_k127_247855_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000001161 197.0
HKD2_k127_247855_4 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.000000000000000000000000000000000000000000000009442 183.0
HKD2_k127_247855_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000006996 174.0
HKD2_k127_247855_6 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000004738 176.0
HKD2_k127_247855_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000004731 152.0
HKD2_k127_247855_8 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000001144 145.0
HKD2_k127_247855_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000004728 134.0
HKD2_k127_2487559_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 553.0
HKD2_k127_2487559_1 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 497.0
HKD2_k127_2487559_10 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000001924 146.0
HKD2_k127_2487559_12 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000009927 130.0
HKD2_k127_2487559_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000196 111.0
HKD2_k127_2487559_14 Isthmin 2 - - - 0.0000000006925 69.0
HKD2_k127_2487559_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 390.0
HKD2_k127_2487559_3 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 376.0
HKD2_k127_2487559_4 Mandelate racemase muconate lactonizing enzyme K02549,K19802 - 4.2.1.113,5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 359.0
HKD2_k127_2487559_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 343.0
HKD2_k127_2487559_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 308.0
HKD2_k127_2487559_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 310.0
HKD2_k127_2487559_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000009149 195.0
HKD2_k127_2487559_9 acetyltransferase K18815 - 2.3.1.82 0.00000000000000000000000000000000000000000000007971 179.0
HKD2_k127_2630258_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.9e-210 672.0
HKD2_k127_2630258_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 1.69e-197 626.0
HKD2_k127_2630258_10 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 329.0
HKD2_k127_2630258_11 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 302.0
HKD2_k127_2630258_12 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001374 280.0
HKD2_k127_2630258_13 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
HKD2_k127_2630258_14 Stimulus-sensing domain K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001568 274.0
HKD2_k127_2630258_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000004088 263.0
HKD2_k127_2630258_16 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000003801 219.0
HKD2_k127_2630258_17 GAF domain - - - 0.000000000000000000000000000000000000000000000000000001435 205.0
HKD2_k127_2630258_18 involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000003524 201.0
HKD2_k127_2630258_19 Short-chain dehydrogenase reductase sdr K15944 - 1.1.1.362 0.000000000000000000000000000000000000000005307 164.0
HKD2_k127_2630258_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 617.0
HKD2_k127_2630258_20 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000002488 156.0
HKD2_k127_2630258_21 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000001686 151.0
HKD2_k127_2630258_22 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000009681 153.0
HKD2_k127_2630258_23 Rubrerythrin - - - 0.0000000000000000000000000000000002918 136.0
HKD2_k127_2630258_24 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000000000000000000000000000000008121 133.0
HKD2_k127_2630258_25 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000141 147.0
HKD2_k127_2630258_26 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000003046 121.0
HKD2_k127_2630258_27 von Willebrand factor, type A K07114 - - 0.0000000000000000000000001582 124.0
HKD2_k127_2630258_28 PFAM O-Antigen K02847 - - 0.000000000000000000001979 108.0
HKD2_k127_2630258_29 ATPase or kinase K06925 - - 0.00000000000000003452 91.0
HKD2_k127_2630258_3 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 597.0
HKD2_k127_2630258_30 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000008044 83.0
HKD2_k127_2630258_31 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000001189 77.0
HKD2_k127_2630258_33 Tetratricopeptide repeat - - - 0.0000003186 64.0
HKD2_k127_2630258_34 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000005486 57.0
HKD2_k127_2630258_35 Acetyltransferase (GNAT) domain - - - 0.0001654 53.0
HKD2_k127_2630258_36 2Fe-2S iron-sulfur cluster binding domain K00305 - 1.5.3.1 0.0005888 47.0
HKD2_k127_2630258_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 526.0
HKD2_k127_2630258_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 526.0
HKD2_k127_2630258_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 459.0
HKD2_k127_2630258_7 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 482.0
HKD2_k127_2630258_8 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 462.0
HKD2_k127_2630258_9 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 347.0
HKD2_k127_2656894_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1422.0
HKD2_k127_2656894_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 345.0
HKD2_k127_2656894_2 PFAM Outer membrane efflux protein - - - 0.00000000002859 76.0
HKD2_k127_2656894_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00003883 53.0
HKD2_k127_2671715_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 473.0
HKD2_k127_2751693_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.219e-228 724.0
HKD2_k127_2751693_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 509.0
HKD2_k127_2751693_10 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000004353 194.0
HKD2_k127_2751693_11 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000001384 190.0
HKD2_k127_2751693_14 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000193 178.0
HKD2_k127_2751693_15 the current gene model (or a revised gene model) may contain a premature stop - - - 0.00000000000000000000000000000000000000005918 153.0
HKD2_k127_2751693_16 - - - - 0.0000000000000000000000000000000000000002689 151.0
HKD2_k127_2751693_17 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000006356 165.0
HKD2_k127_2751693_19 - - - - 0.000000000000000000000000000000000006675 139.0
HKD2_k127_2751693_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 342.0
HKD2_k127_2751693_20 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000002371 123.0
HKD2_k127_2751693_21 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000004274 122.0
HKD2_k127_2751693_22 Putative regulatory protein - - - 0.00000000000000000000000003842 124.0
HKD2_k127_2751693_23 - - - - 0.00000000000000000000001492 104.0
HKD2_k127_2751693_24 - - - - 0.0000000000000000000004522 98.0
HKD2_k127_2751693_25 - - - - 0.000000000000000004824 86.0
HKD2_k127_2751693_26 - - - - 0.0000000000000005853 78.0
HKD2_k127_2751693_28 YbbR-like protein - - - 0.0000000000001008 81.0
HKD2_k127_2751693_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 335.0
HKD2_k127_2751693_30 - - - - 0.000000000008874 66.0
HKD2_k127_2751693_32 TonB C terminal K03646,K03832 - - 0.00000000001417 74.0
HKD2_k127_2751693_33 - - - - 0.00000000004444 65.0
HKD2_k127_2751693_35 PMT family glycosyltransferase, 4-amino-4-deoxy-L-arabinose transferase - - - 0.000000005566 66.0
HKD2_k127_2751693_36 - - - - 0.00000001201 57.0
HKD2_k127_2751693_37 - - - - 0.00000005617 56.0
HKD2_k127_2751693_39 ORF located using Blastx - - - 0.0000002049 61.0
HKD2_k127_2751693_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 333.0
HKD2_k127_2751693_41 - - - - 0.00001595 48.0
HKD2_k127_2751693_42 - - - - 0.0000168 51.0
HKD2_k127_2751693_43 - - - - 0.0001474 55.0
HKD2_k127_2751693_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003169 268.0
HKD2_k127_2751693_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000002161 259.0
HKD2_k127_2751693_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
HKD2_k127_2751693_8 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000004008 209.0
HKD2_k127_2751693_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000002735 200.0
HKD2_k127_2764368_0 Tricorn protease homolog - - - 0.0 1327.0
HKD2_k127_2764368_1 Alpha amylase, catalytic domain - - - 0.0 1191.0
HKD2_k127_2764368_10 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 547.0
HKD2_k127_2764368_11 Alcohol dehydrogenase GroES-like domain K13979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 505.0
HKD2_k127_2764368_12 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 505.0
HKD2_k127_2764368_13 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 480.0
HKD2_k127_2764368_14 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 452.0
HKD2_k127_2764368_15 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 441.0
HKD2_k127_2764368_16 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 435.0
HKD2_k127_2764368_17 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 426.0
HKD2_k127_2764368_18 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 399.0
HKD2_k127_2764368_19 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 381.0
HKD2_k127_2764368_2 Tricorn protease C1 domain K08676 - - 0.0 1178.0
HKD2_k127_2764368_20 PFAM amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 386.0
HKD2_k127_2764368_21 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 366.0
HKD2_k127_2764368_22 N-acyl-L-amino acid amidohydrolase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 347.0
HKD2_k127_2764368_23 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 321.0
HKD2_k127_2764368_24 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
HKD2_k127_2764368_25 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004987 299.0
HKD2_k127_2764368_26 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000006609 227.0
HKD2_k127_2764368_27 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000000000000007478 212.0
HKD2_k127_2764368_28 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000001709 213.0
HKD2_k127_2764368_29 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000132 198.0
HKD2_k127_2764368_3 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 6.149e-254 788.0
HKD2_k127_2764368_30 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000003628 198.0
HKD2_k127_2764368_31 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000025 184.0
HKD2_k127_2764368_32 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000003098 194.0
HKD2_k127_2764368_33 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000004123 175.0
HKD2_k127_2764368_34 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000004764 169.0
HKD2_k127_2764368_35 lipase activity K15349 - - 0.000000000000000000000000000000000000000009288 171.0
HKD2_k127_2764368_36 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000002364 158.0
HKD2_k127_2764368_37 D-serine dehydratase-like - - - 0.00000000000000000000000000000000000001699 155.0
HKD2_k127_2764368_38 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000001001 136.0
HKD2_k127_2764368_39 actin binding - - - 0.00000000000000000000001987 105.0
HKD2_k127_2764368_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.744e-245 782.0
HKD2_k127_2764368_40 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000359 98.0
HKD2_k127_2764368_41 NnrU protein - - - 0.00000000000000003298 91.0
HKD2_k127_2764368_42 - - - - 0.000000000006988 79.0
HKD2_k127_2764368_43 - - - - 0.0000000001902 74.0
HKD2_k127_2764368_44 - - - - 0.00000006996 62.0
HKD2_k127_2764368_45 Psort location CytoplasmicMembrane, score - - - 0.000007821 58.0
HKD2_k127_2764368_5 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 3.737e-210 684.0
HKD2_k127_2764368_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 602.0
HKD2_k127_2764368_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 586.0
HKD2_k127_2764368_8 Aldo keto reductase K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 524.0
HKD2_k127_2764368_9 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 540.0
HKD2_k127_2781409_0 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 527.0
HKD2_k127_2781409_1 PFAM purine or other phosphorylase family 1 - - - 0.00000000000001915 82.0
HKD2_k127_2927341_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 625.0
HKD2_k127_2927341_1 peptidase K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 488.0
HKD2_k127_2927341_10 PFAM TENA THI-4 PQQC family K03707 - 3.5.99.2 0.000000000000000000000000000000000000000000000000000003602 199.0
HKD2_k127_2927341_11 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000001338 145.0
HKD2_k127_2927341_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000002833 159.0
HKD2_k127_2927341_13 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000002202 135.0
HKD2_k127_2927341_14 - - - - 0.00000000000000000002477 100.0
HKD2_k127_2927341_15 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000001873 95.0
HKD2_k127_2927341_18 - - - - 0.000002799 57.0
HKD2_k127_2927341_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 457.0
HKD2_k127_2927341_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 432.0
HKD2_k127_2927341_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 396.0
HKD2_k127_2927341_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 308.0
HKD2_k127_2927341_6 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 281.0
HKD2_k127_2927341_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000004823 249.0
HKD2_k127_2927341_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001907 237.0
HKD2_k127_2927341_9 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000481 226.0
HKD2_k127_2937458_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1715.0
HKD2_k127_2937458_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1706.0
HKD2_k127_2937458_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000009059 125.0
HKD2_k127_2937458_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000008779 79.0
HKD2_k127_2937458_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00001734 49.0
HKD2_k127_2937458_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0009906 45.0
HKD2_k127_2937458_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.619e-308 956.0
HKD2_k127_2937458_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.174e-207 650.0
HKD2_k127_2937458_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 286.0
HKD2_k127_2937458_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000005362 233.0
HKD2_k127_2937458_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006437 226.0
HKD2_k127_2937458_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001831 217.0
HKD2_k127_2937458_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002259 216.0
HKD2_k127_2937458_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000009368 152.0
HKD2_k127_2955303_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 498.0
HKD2_k127_2955303_1 COG0553 Superfamily II DNA RNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 451.0
HKD2_k127_2955303_10 - - - - 0.00000000000001293 77.0
HKD2_k127_2955303_11 TIGRFAM VWFA-related Acidobacterial domain K07114,K12511 - - 0.000000000003607 79.0
HKD2_k127_2955303_2 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000584 244.0
HKD2_k127_2955303_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000005704 239.0
HKD2_k127_2955303_4 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000001939 224.0
HKD2_k127_2955303_5 IstB-like ATP binding protein K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000001738 197.0
HKD2_k127_2955303_6 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000001032 160.0
HKD2_k127_2955303_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000000000009268 148.0
HKD2_k127_2955303_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000007399 132.0
HKD2_k127_2955303_9 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000008327 102.0
HKD2_k127_2988313_0 ABC 3 transport family K11708 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 383.0
HKD2_k127_2988313_1 PFAM ABC-3 protein K11709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 392.0
HKD2_k127_2988313_10 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000001707 148.0
HKD2_k127_2988313_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002217 127.0
HKD2_k127_2988313_12 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000849 116.0
HKD2_k127_2988313_13 response regulator, receiver - - - 0.0000000000000000004673 102.0
HKD2_k127_2988313_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000001046 63.0
HKD2_k127_2988313_15 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000001103 57.0
HKD2_k127_2988313_2 Zinc-uptake complex component A periplasmic K09815,K11707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 349.0
HKD2_k127_2988313_3 PFAM ABC transporter related K11710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 328.0
HKD2_k127_2988313_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002971 274.0
HKD2_k127_2988313_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000001821 252.0
HKD2_k127_2988313_6 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
HKD2_k127_2988313_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000002747 206.0
HKD2_k127_2988313_8 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000001777 190.0
HKD2_k127_2988313_9 Kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000006915 200.0
HKD2_k127_3035626_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 518.0
HKD2_k127_3035626_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 333.0
HKD2_k127_3035626_2 DHH family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004484 251.0
HKD2_k127_3035626_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
HKD2_k127_3035626_4 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000002705 200.0
HKD2_k127_3035626_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000001799 165.0
HKD2_k127_3059783_0 ATP-grasp domain - - - 3.36e-230 739.0
HKD2_k127_3059783_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 565.0
HKD2_k127_3059783_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 464.0
HKD2_k127_3059783_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009668 273.0
HKD2_k127_3059783_4 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006803 248.0
HKD2_k127_3059783_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000006899 239.0
HKD2_k127_3059783_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000006314 224.0
HKD2_k127_3059783_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179,K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000003119 223.0
HKD2_k127_3059783_8 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000006298 81.0
HKD2_k127_3059783_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000001791 68.0
HKD2_k127_3219238_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 486.0
HKD2_k127_3219238_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 417.0
HKD2_k127_3219238_10 Histidine kinase - - - 0.000000000000000000005628 105.0
HKD2_k127_3219238_11 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.0000000000000000004385 103.0
HKD2_k127_3219238_12 - - - - 0.000000000003444 79.0
HKD2_k127_3219238_2 PFAM Pyridoxal phosphate-dependent enzyme, beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 401.0
HKD2_k127_3219238_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 397.0
HKD2_k127_3219238_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 359.0
HKD2_k127_3219238_5 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 317.0
HKD2_k127_3219238_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 291.0
HKD2_k127_3219238_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001972 256.0
HKD2_k127_3219238_8 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000008579 186.0
HKD2_k127_3219238_9 metallopeptidase activity - - - 0.0000000000000000000000000001761 134.0
HKD2_k127_341820_0 mannose metabolic process K01191 - 3.2.1.24 2.702e-283 917.0
HKD2_k127_341820_1 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 6.737e-237 743.0
HKD2_k127_341820_10 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 426.0
HKD2_k127_341820_11 DNA-templated transcription, termination K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 352.0
HKD2_k127_341820_12 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 348.0
HKD2_k127_341820_13 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 336.0
HKD2_k127_341820_14 PFAM ABC-3 protein K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 307.0
HKD2_k127_341820_15 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006658 282.0
HKD2_k127_341820_16 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K10440,K17206 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008248 280.0
HKD2_k127_341820_17 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 280.0
HKD2_k127_341820_18 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007879 263.0
HKD2_k127_341820_19 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002338 264.0
HKD2_k127_341820_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 619.0
HKD2_k127_341820_20 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005196 260.0
HKD2_k127_341820_21 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008314 241.0
HKD2_k127_341820_22 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000001123 220.0
HKD2_k127_341820_23 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000000000000000000000000000000000000000316 232.0
HKD2_k127_341820_24 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.000000000000000000000000000000000006332 146.0
HKD2_k127_341820_25 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000000000001946 139.0
HKD2_k127_341820_26 GIY-YIG catalytic domain - - - 0.000000000000000000000000000009378 120.0
HKD2_k127_341820_27 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000006492 111.0
HKD2_k127_341820_28 Regulatory protein, FmdB - - - 0.000000000000000000000008089 104.0
HKD2_k127_341820_29 - - - - 0.000000000000000000002207 96.0
HKD2_k127_341820_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 571.0
HKD2_k127_341820_31 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.0000000000002656 80.0
HKD2_k127_341820_32 Belongs to the peptidase M10A family K07996 - - 0.0000005431 62.0
HKD2_k127_341820_33 - - - - 0.0000184 48.0
HKD2_k127_341820_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 521.0
HKD2_k127_341820_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 511.0
HKD2_k127_341820_6 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 461.0
HKD2_k127_341820_7 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 473.0
HKD2_k127_341820_8 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 456.0
HKD2_k127_341820_9 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 451.0
HKD2_k127_3587233_0 Belongs to the ClpA ClpB family K03696 - - 7.081e-279 880.0
HKD2_k127_3587233_1 belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 7.067e-244 763.0
HKD2_k127_3587233_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 336.0
HKD2_k127_3587233_11 Sir2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 336.0
HKD2_k127_3587233_12 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 351.0
HKD2_k127_3587233_13 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 308.0
HKD2_k127_3587233_14 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 301.0
HKD2_k127_3587233_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004043 279.0
HKD2_k127_3587233_16 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
HKD2_k127_3587233_17 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006278 246.0
HKD2_k127_3587233_18 TrkA-N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002026 239.0
HKD2_k127_3587233_19 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000001366 245.0
HKD2_k127_3587233_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 547.0
HKD2_k127_3587233_20 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000001534 226.0
HKD2_k127_3587233_21 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000008192 203.0
HKD2_k127_3587233_22 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000005624 193.0
HKD2_k127_3587233_23 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000006119 201.0
HKD2_k127_3587233_24 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000681 172.0
HKD2_k127_3587233_25 Haem-binding domain - - - 0.000000000000000000000000000000000000000002216 160.0
HKD2_k127_3587233_26 iron-sulfur cluster assembly K07400,K13628 - - 0.000000000000000000000000000000000000001903 153.0
HKD2_k127_3587233_27 Initiation factor 2 subunit family K08963 - 5.3.1.23 0.0000000000000000000000000000002684 138.0
HKD2_k127_3587233_28 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000001894 126.0
HKD2_k127_3587233_29 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000004813 106.0
HKD2_k127_3587233_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 537.0
HKD2_k127_3587233_30 PFAM Transposase IS200 like - - - 0.0000000000000000000003274 111.0
HKD2_k127_3587233_31 Iron-sulfur cluster-binding domain - - - 0.000000000000000000001027 107.0
HKD2_k127_3587233_32 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000002414 93.0
HKD2_k127_3587233_33 methyltransferase - - - 0.00000000000000003855 91.0
HKD2_k127_3587233_34 MacB-like periplasmic core domain K09808 - - 0.0000000000000001449 95.0
HKD2_k127_3587233_35 Domain of unknown function DUF302 - - - 0.000000000000009863 81.0
HKD2_k127_3587233_36 DUF167 K09131 - - 0.000000000000232 76.0
HKD2_k127_3587233_37 cellulase activity - - - 0.000000000001747 81.0
HKD2_k127_3587233_38 - - - - 0.000000000002469 73.0
HKD2_k127_3587233_39 Outer membrane protein beta-barrel domain K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000668 76.0
HKD2_k127_3587233_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 503.0
HKD2_k127_3587233_40 PFAM DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000001547 60.0
HKD2_k127_3587233_41 PFAM Outer membrane K06142 - - 0.0000003687 62.0
HKD2_k127_3587233_42 ankyrin repeat K06867 - - 0.00021 54.0
HKD2_k127_3587233_43 - - - - 0.0006036 50.0
HKD2_k127_3587233_5 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 428.0
HKD2_k127_3587233_6 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 417.0
HKD2_k127_3587233_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 418.0
HKD2_k127_3587233_8 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 391.0
HKD2_k127_3587233_9 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 383.0
HKD2_k127_3616920_0 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 419.0
HKD2_k127_3616920_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 341.0
HKD2_k127_3616920_10 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000003106 70.0
HKD2_k127_3616920_2 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005137 261.0
HKD2_k127_3616920_3 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000006324 220.0
HKD2_k127_3616920_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000272 188.0
HKD2_k127_3616920_5 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000000000000001126 162.0
HKD2_k127_3616920_6 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000006931 137.0
HKD2_k127_3616920_7 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000001339 106.0
HKD2_k127_3616920_8 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000006397 98.0
HKD2_k127_3616920_9 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000001641 96.0
HKD2_k127_3650865_0 Sulfatase K01130 - 3.1.6.1 0.0 1222.0
HKD2_k127_3650865_1 Heat shock 70 kDa protein K04043 - - 3.102e-281 877.0
HKD2_k127_3650865_10 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007371 286.0
HKD2_k127_3650865_11 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000006004 262.0
HKD2_k127_3650865_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000368 231.0
HKD2_k127_3650865_13 ligase activity, forming carbon-carbon bonds K07402 - - 0.00000000000000000000000000000000000000000000000007929 192.0
HKD2_k127_3650865_14 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000005465 172.0
HKD2_k127_3650865_15 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000003732 182.0
HKD2_k127_3650865_16 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.0000000000000000000000000000000000000000006524 180.0
HKD2_k127_3650865_17 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000001839 151.0
HKD2_k127_3650865_18 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000009594 148.0
HKD2_k127_3650865_19 peptidase - - - 0.0000000000000000000000000000000000002836 155.0
HKD2_k127_3650865_2 DEAD DEAH box helicase - - - 4.432e-256 818.0
HKD2_k127_3650865_20 Protein conserved in bacteria - - - 0.000000000000000000000000000000000001525 158.0
HKD2_k127_3650865_21 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000784 141.0
HKD2_k127_3650865_22 - - - - 0.0000000000000000000000000000000008379 144.0
HKD2_k127_3650865_23 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000001076 120.0
HKD2_k127_3650865_24 RDD family - - - 0.000000000003708 74.0
HKD2_k127_3650865_25 - - - - 0.00000002141 57.0
HKD2_k127_3650865_26 Tetratricopeptide repeat - - - 0.0000005034 63.0
HKD2_k127_3650865_27 Domain of unknown function (DUF1844) - - - 0.00002958 56.0
HKD2_k127_3650865_3 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 1.945e-236 762.0
HKD2_k127_3650865_4 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 619.0
HKD2_k127_3650865_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 469.0
HKD2_k127_3650865_6 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 441.0
HKD2_k127_3650865_7 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 367.0
HKD2_k127_3650865_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 343.0
HKD2_k127_3650865_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 336.0
HKD2_k127_3849520_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 524.0
HKD2_k127_3849520_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000009871 235.0
HKD2_k127_3849520_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000004277 186.0
HKD2_k127_3849520_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000005867 145.0
HKD2_k127_3849520_4 PFAM Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000001314 109.0
HKD2_k127_3849520_5 Transcription elongation factor, N-terminal - - - 0.0000000000000003924 93.0
HKD2_k127_3856132_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 7.697e-198 633.0
HKD2_k127_3856132_1 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 591.0
HKD2_k127_3856132_10 sulfurtransferase activity K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 386.0
HKD2_k127_3856132_11 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 385.0
HKD2_k127_3856132_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 376.0
HKD2_k127_3856132_13 restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 355.0
HKD2_k127_3856132_14 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 341.0
HKD2_k127_3856132_15 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 336.0
HKD2_k127_3856132_16 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 304.0
HKD2_k127_3856132_17 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 309.0
HKD2_k127_3856132_18 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 299.0
HKD2_k127_3856132_19 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 297.0
HKD2_k127_3856132_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 529.0
HKD2_k127_3856132_20 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001844 316.0
HKD2_k127_3856132_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008979 250.0
HKD2_k127_3856132_22 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000001989 265.0
HKD2_k127_3856132_23 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003878 229.0
HKD2_k127_3856132_24 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000005207 224.0
HKD2_k127_3856132_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000006918 226.0
HKD2_k127_3856132_26 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
HKD2_k127_3856132_27 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000001832 215.0
HKD2_k127_3856132_28 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000000000000000000000000000003233 203.0
HKD2_k127_3856132_29 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001177 206.0
HKD2_k127_3856132_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 505.0
HKD2_k127_3856132_30 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000000000000008749 183.0
HKD2_k127_3856132_31 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000005248 185.0
HKD2_k127_3856132_32 PFAM ATP-binding region ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000009908 185.0
HKD2_k127_3856132_33 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000001191 174.0
HKD2_k127_3856132_34 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000786 156.0
HKD2_k127_3856132_35 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000006788 153.0
HKD2_k127_3856132_36 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000005946 154.0
HKD2_k127_3856132_37 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000007855 146.0
HKD2_k127_3856132_38 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000002008 140.0
HKD2_k127_3856132_39 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624,K06140 - - 0.0000000000000000000000000007499 118.0
HKD2_k127_3856132_4 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 454.0
HKD2_k127_3856132_40 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000001082 117.0
HKD2_k127_3856132_41 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000001643 109.0
HKD2_k127_3856132_42 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000001259 110.0
HKD2_k127_3856132_43 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000004257 115.0
HKD2_k127_3856132_44 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.99 0.0000000000000000000001068 113.0
HKD2_k127_3856132_45 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000007396 96.0
HKD2_k127_3856132_46 Helix-hairpin-helix motif K02237 - - 0.000000000000000000831 90.0
HKD2_k127_3856132_47 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000004391 90.0
HKD2_k127_3856132_49 Peptidase family S58 K01266 - 3.4.11.19 0.0000000007917 63.0
HKD2_k127_3856132_5 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 432.0
HKD2_k127_3856132_50 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.11 0.000000001318 69.0
HKD2_k127_3856132_51 cyclic nucleotide-binding K01420,K21563 - - 0.00000003202 65.0
HKD2_k127_3856132_52 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00007762 55.0
HKD2_k127_3856132_6 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 404.0
HKD2_k127_3856132_7 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 395.0
HKD2_k127_3856132_8 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 389.0
HKD2_k127_3856132_9 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 402.0
HKD2_k127_3860653_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1299.0
HKD2_k127_3860653_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HKD2_k127_3860653_2 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000007793 183.0
HKD2_k127_3870949_0 reductase alpha subunit K00394 - 1.8.99.2 0.0 1011.0
HKD2_k127_3870949_1 Protein of unknown function, DUF255 K06888 - - 2.228e-227 724.0
HKD2_k127_3870949_10 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.0000003248 52.0
HKD2_k127_3870949_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.189e-214 691.0
HKD2_k127_3870949_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 477.0
HKD2_k127_3870949_4 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 380.0
HKD2_k127_3870949_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 302.0
HKD2_k127_3870949_6 reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000001425 235.0
HKD2_k127_3870949_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000004583 211.0
HKD2_k127_3870949_8 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000199 182.0
HKD2_k127_3870949_9 Ogr/Delta-like zinc finger - - - 0.000000000000000000003485 97.0
HKD2_k127_3898532_0 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 491.0
HKD2_k127_3898532_1 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 456.0
HKD2_k127_3898532_10 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000001872 117.0
HKD2_k127_3898532_11 Psort location Cytoplasmic, score - - - 0.00000001612 68.0
HKD2_k127_3898532_12 Domain of unknown function (DUF4388) K02274 - 1.9.3.1 0.00000006457 62.0
HKD2_k127_3898532_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 321.0
HKD2_k127_3898532_3 Pkd domain containing protein K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 310.0
HKD2_k127_3898532_4 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
HKD2_k127_3898532_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005747 272.0
HKD2_k127_3898532_6 mRNA catabolic process K06950,K09163 - - 0.0000000000000000000000000000000000000000000000000000000000000004184 224.0
HKD2_k127_3898532_7 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000006404 203.0
HKD2_k127_3898532_8 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000002366 170.0
HKD2_k127_3898532_9 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000001475 131.0
HKD2_k127_3912765_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.175e-230 736.0
HKD2_k127_3912765_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.951e-213 679.0
HKD2_k127_3912765_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 409.0
HKD2_k127_3912765_11 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 400.0
HKD2_k127_3912765_12 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 377.0
HKD2_k127_3912765_13 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 369.0
HKD2_k127_3912765_14 protein-disulfide reductase activity K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 361.0
HKD2_k127_3912765_15 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 352.0
HKD2_k127_3912765_16 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 338.0
HKD2_k127_3912765_17 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 271.0
HKD2_k127_3912765_18 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008363 248.0
HKD2_k127_3912765_19 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000008389 239.0
HKD2_k127_3912765_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.679e-206 658.0
HKD2_k127_3912765_20 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000109 237.0
HKD2_k127_3912765_21 agmatine deiminase activity K08589,K10536,K20276 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37,3.5.3.12 0.000000000000000000000000000000000000000000000000000000004872 228.0
HKD2_k127_3912765_22 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000387 205.0
HKD2_k127_3912765_23 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000004838 209.0
HKD2_k127_3912765_24 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000001302 191.0
HKD2_k127_3912765_25 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000251 173.0
HKD2_k127_3912765_26 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000001145 164.0
HKD2_k127_3912765_27 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000003038 170.0
HKD2_k127_3912765_28 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000007322 168.0
HKD2_k127_3912765_29 GAF domain K08968 - 1.8.4.14 0.0000000000000000000000000000000000000001003 157.0
HKD2_k127_3912765_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.178e-201 658.0
HKD2_k127_3912765_30 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000001736 160.0
HKD2_k127_3912765_31 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000003547 140.0
HKD2_k127_3912765_32 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000002101 147.0
HKD2_k127_3912765_33 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000001554 149.0
HKD2_k127_3912765_34 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000008342 145.0
HKD2_k127_3912765_35 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000003069 132.0
HKD2_k127_3912765_36 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000001936 135.0
HKD2_k127_3912765_37 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000002232 122.0
HKD2_k127_3912765_38 RimM N-terminal domain K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000002428 121.0
HKD2_k127_3912765_39 domain, Protein K15125,K21449 - - 0.000000000000000000000000006921 129.0
HKD2_k127_3912765_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 576.0
HKD2_k127_3912765_40 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000001531 109.0
HKD2_k127_3912765_41 Could be involved in septation K06412 - - 0.00000000000000000004794 94.0
HKD2_k127_3912765_42 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000005458 101.0
HKD2_k127_3912765_43 S4 RNA-binding domain K04762 - - 0.0000000000000000005727 94.0
HKD2_k127_3912765_44 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000162 94.0
HKD2_k127_3912765_45 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000002059 84.0
HKD2_k127_3912765_46 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000007602 93.0
HKD2_k127_3912765_47 helix_turn_helix, Lux Regulon - - - 0.0000000000000001402 90.0
HKD2_k127_3912765_48 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000002521 75.0
HKD2_k127_3912765_49 WD40 repeats - - - 0.00000000007173 76.0
HKD2_k127_3912765_5 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 538.0
HKD2_k127_3912765_50 Protein of unknown function (DUF503) K09764 - - 0.0000000006729 66.0
HKD2_k127_3912765_51 oxidoreductase activity - - - 0.00000001554 68.0
HKD2_k127_3912765_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 475.0
HKD2_k127_3912765_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 474.0
HKD2_k127_3912765_8 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 447.0
HKD2_k127_3912765_9 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 426.0
HKD2_k127_4017586_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 412.0
HKD2_k127_4017586_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 351.0
HKD2_k127_4017586_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000001004 128.0
HKD2_k127_4017586_3 - - - - 0.000000000000002436 89.0
HKD2_k127_4071998_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1109.0
HKD2_k127_4071998_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1086.0
HKD2_k127_4071998_10 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004339 273.0
HKD2_k127_4071998_12 - - - - 0.00000001859 66.0
HKD2_k127_4071998_13 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000001458 63.0
HKD2_k127_4071998_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 5.454e-265 848.0
HKD2_k127_4071998_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 2.08e-211 664.0
HKD2_k127_4071998_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 572.0
HKD2_k127_4071998_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 577.0
HKD2_k127_4071998_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 576.0
HKD2_k127_4071998_7 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 415.0
HKD2_k127_4071998_8 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 433.0
HKD2_k127_4071998_9 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 417.0
HKD2_k127_4101391_0 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 4.095e-194 630.0
HKD2_k127_4101391_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 548.0
HKD2_k127_4101391_10 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.00000002897 67.0
HKD2_k127_4101391_11 WD40 repeats - - - 0.00001565 59.0
HKD2_k127_4101391_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 351.0
HKD2_k127_4101391_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004873 280.0
HKD2_k127_4101391_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 277.0
HKD2_k127_4101391_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004566 262.0
HKD2_k127_4101391_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004884 253.0
HKD2_k127_4101391_7 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000004156 196.0
HKD2_k127_4101391_8 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000002729 158.0
HKD2_k127_4129556_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
HKD2_k127_4129556_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 322.0
HKD2_k127_4129556_10 Fungalysin metallopeptidase (M36) - - - 0.0003264 50.0
HKD2_k127_4129556_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 313.0
HKD2_k127_4129556_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003168 253.0
HKD2_k127_4129556_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000006748 240.0
HKD2_k127_4129556_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000139 198.0
HKD2_k127_4129556_6 - - - - 0.00000000000000000000000001985 119.0
HKD2_k127_4129556_7 PLD-like domain K06132 - - 0.00000000000000000000006984 113.0
HKD2_k127_4129556_8 Yip1 domain - - - 0.00000000000002673 83.0
HKD2_k127_4129556_9 - - - - 0.00000000000006882 76.0
HKD2_k127_4187368_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 1.196e-205 664.0
HKD2_k127_4187368_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 306.0
HKD2_k127_4187368_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
HKD2_k127_4187368_3 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000001204 231.0
HKD2_k127_4187368_4 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000001658 250.0
HKD2_k127_4187368_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000008601 198.0
HKD2_k127_4187368_6 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000683 129.0
HKD2_k127_4187368_7 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000003035 112.0
HKD2_k127_4187529_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 6.296e-318 1002.0
HKD2_k127_4187529_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 5.826e-229 726.0
HKD2_k127_4187529_10 Protein of unknown function (DUF229) - - - 0.000000000000002272 89.0
HKD2_k127_4187529_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 543.0
HKD2_k127_4187529_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 386.0
HKD2_k127_4187529_4 Peptidase family M1 domain K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002878 251.0
HKD2_k127_4187529_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000326 225.0
HKD2_k127_4187529_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000001556 217.0
HKD2_k127_4187529_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000233 124.0
HKD2_k127_4187529_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000004571 109.0
HKD2_k127_4187529_9 - - - - 0.0000000000000000004092 102.0
HKD2_k127_4233524_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 324.0
HKD2_k127_4233524_1 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001019 246.0
HKD2_k127_4292447_0 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 399.0
HKD2_k127_4292447_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 338.0
HKD2_k127_4292447_10 Roadblock/LC7 domain - - - 0.000001279 61.0
HKD2_k127_4292447_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 308.0
HKD2_k127_4292447_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 306.0
HKD2_k127_4292447_4 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 305.0
HKD2_k127_4292447_5 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000001828 194.0
HKD2_k127_4292447_6 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000001784 160.0
HKD2_k127_4292447_7 Response regulator receiver domain - - - 0.0000000000000000000000000000001797 128.0
HKD2_k127_4292447_8 Tetratricopeptide repeat - - - 0.00000000000003434 85.0
HKD2_k127_4292447_9 Dodecin K09165 - - 0.0000000001486 65.0
HKD2_k127_4299130_0 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 517.0
HKD2_k127_4299130_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 338.0
HKD2_k127_4299130_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000004948 260.0
HKD2_k127_4299130_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000008714 215.0
HKD2_k127_4299130_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000009783 208.0
HKD2_k127_4299130_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000006307 151.0
HKD2_k127_4299130_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000781 135.0
HKD2_k127_4299130_7 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000002098 110.0
HKD2_k127_4299130_8 Fibronectin type III domain protein - - - 0.000000000000000000001178 108.0
HKD2_k127_4299130_9 Protein of unknown function (DUF1573) - - - 0.0000000000000002914 93.0
HKD2_k127_4383899_0 ABC transporter K06020 - 3.6.3.25 8.286e-221 693.0
HKD2_k127_4383899_1 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 574.0
HKD2_k127_4383899_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000001212 107.0
HKD2_k127_4400041_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 495.0
HKD2_k127_4400041_1 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 490.0
HKD2_k127_4400041_10 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000001524 175.0
HKD2_k127_4400041_11 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.00000000000000000000000000000001008 144.0
HKD2_k127_4400041_12 histidine kinase A domain protein - - - 0.000000000000000000000000000006663 126.0
HKD2_k127_4400041_13 - - - - 0.0000000000000000006766 96.0
HKD2_k127_4400041_14 SPTR Peptidase S8 and S53 subtilisin kexin sedolisin K01113,K14645,K17713 - 3.1.3.1 0.000000000000000001717 100.0
HKD2_k127_4400041_15 - K02450 - - 0.000000005631 67.0
HKD2_k127_4400041_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 490.0
HKD2_k127_4400041_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 449.0
HKD2_k127_4400041_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 337.0
HKD2_k127_4400041_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 311.0
HKD2_k127_4400041_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005678 273.0
HKD2_k127_4400041_7 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000317 253.0
HKD2_k127_4400041_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000006582 203.0
HKD2_k127_4400041_9 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000001206 184.0
HKD2_k127_4708537_0 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008401 613.0
HKD2_k127_4708537_1 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 568.0
HKD2_k127_4708537_10 heat shock protein binding - - - 0.0000000000000000000000000000000000000000001998 184.0
HKD2_k127_4708537_11 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000007349 160.0
HKD2_k127_4708537_12 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000001601 161.0
HKD2_k127_4708537_13 SMART Tetratricopeptide - - - 0.000000000000000000004189 102.0
HKD2_k127_4708537_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000002269 95.0
HKD2_k127_4708537_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000284 66.0
HKD2_k127_4708537_16 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000005058 66.0
HKD2_k127_4708537_17 - - - - 0.00000006283 61.0
HKD2_k127_4708537_18 Predicted membrane protein (DUF2085) - - - 0.00008589 53.0
HKD2_k127_4708537_19 Tetratricopeptide repeat - - - 0.00008669 54.0
HKD2_k127_4708537_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 550.0
HKD2_k127_4708537_3 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 431.0
HKD2_k127_4708537_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 434.0
HKD2_k127_4708537_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 345.0
HKD2_k127_4708537_6 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004746 266.0
HKD2_k127_4708537_7 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000002304 229.0
HKD2_k127_4708537_8 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001102 216.0
HKD2_k127_4708537_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000004809 184.0
HKD2_k127_4927219_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 636.0
HKD2_k127_4927219_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 350.0
HKD2_k127_4927219_2 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004554 268.0
HKD2_k127_4927219_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000935 213.0
HKD2_k127_4927219_4 COGs COG5616 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000003514 216.0
HKD2_k127_4927219_5 - - - - 0.00000000000000000000000000000000003079 138.0
HKD2_k127_4927219_6 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000001823 144.0
HKD2_k127_5086111_0 Large extracellular alpha-helical protein - - - 1.793e-267 851.0
HKD2_k127_5101231_0 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 6.629e-311 979.0
HKD2_k127_5101231_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 407.0
HKD2_k127_5101231_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 328.0
HKD2_k127_5101231_3 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 328.0
HKD2_k127_5101231_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000001129 229.0
HKD2_k127_5101231_5 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000287 75.0
HKD2_k127_5134477_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.538e-318 993.0
HKD2_k127_5134477_1 Zinc carboxypeptidase K14054 - - 8.474e-274 872.0
HKD2_k127_5134477_10 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 350.0
HKD2_k127_5134477_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 291.0
HKD2_k127_5134477_12 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000767 253.0
HKD2_k127_5134477_13 ATPase, AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002306 262.0
HKD2_k127_5134477_14 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000002352 243.0
HKD2_k127_5134477_15 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000002909 210.0
HKD2_k127_5134477_16 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000002701 207.0
HKD2_k127_5134477_17 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000009705 196.0
HKD2_k127_5134477_18 Subtilase family - - - 0.0000000000000000000000000000000000000000000000002223 203.0
HKD2_k127_5134477_19 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000005017 197.0
HKD2_k127_5134477_2 Belongs to the malate synthase family K01638 - 2.3.3.9 7.45e-233 731.0
HKD2_k127_5134477_20 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.00000000000000000000000000000000000000000000004643 174.0
HKD2_k127_5134477_21 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.00000000000000000000000000000000000000000000006084 181.0
HKD2_k127_5134477_22 Choloylglycine hydrolase K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000005939 171.0
HKD2_k127_5134477_23 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000102 172.0
HKD2_k127_5134477_24 - - - - 0.000000000000000000000000000000037 139.0
HKD2_k127_5134477_25 regulation of translation K05788 - - 0.000000000000000000000000007342 112.0
HKD2_k127_5134477_26 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000006239 108.0
HKD2_k127_5134477_27 peptidase activity - - - 0.00000000000000001236 94.0
HKD2_k127_5134477_28 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000524 89.0
HKD2_k127_5134477_29 - - - - 0.0000000000001212 80.0
HKD2_k127_5134477_3 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005488,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 597.0
HKD2_k127_5134477_30 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000003889 82.0
HKD2_k127_5134477_31 - - - - 0.0000000000004974 79.0
HKD2_k127_5134477_32 Cell wall formation K00075 - 1.3.1.98 0.000000000003284 77.0
HKD2_k127_5134477_33 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.00000000003347 72.0
HKD2_k127_5134477_34 PFAM VanZ family protein - - - 0.0000002264 57.0
HKD2_k127_5134477_35 sequence-specific DNA binding K15539 - - 0.000004141 57.0
HKD2_k127_5134477_36 Protein of unknown function (DUF1573) - - - 0.00008826 53.0
HKD2_k127_5134477_37 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0001189 51.0
HKD2_k127_5134477_4 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 583.0
HKD2_k127_5134477_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 548.0
HKD2_k127_5134477_6 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 522.0
HKD2_k127_5134477_7 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 491.0
HKD2_k127_5134477_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 450.0
HKD2_k127_5134477_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 424.0
HKD2_k127_5158098_0 4Fe-4S dicluster domain - - - 4.556e-199 645.0
HKD2_k127_5158098_1 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 579.0
HKD2_k127_5158098_2 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 503.0
HKD2_k127_5158098_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 474.0
HKD2_k127_5158098_4 PFAM Uncharacterised protein family UPF0324 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 435.0
HKD2_k127_5158098_5 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 351.0
HKD2_k127_5158098_6 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000001661 226.0
HKD2_k127_5158098_7 histidine kinase A domain protein - - - 0.000000000000000000000000000000007865 144.0
HKD2_k127_5158098_8 DSBA-like thioredoxin domain - - - 0.000000000000000004838 97.0
HKD2_k127_5158098_9 Protein of unknown function (DUF2723) - - - 0.0002172 54.0
HKD2_k127_5208306_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 503.0
HKD2_k127_5232613_0 Sortilin, neurotensin receptor 3, - - - 0.0 1099.0
HKD2_k127_5232613_1 Transport of potassium into the cell K03549 - - 2.478e-229 730.0
HKD2_k127_5232613_10 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000006796 186.0
HKD2_k127_5232613_11 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000004786 135.0
HKD2_k127_5232613_12 Transposase IS200 like - - - 0.00000000000000000000000002467 121.0
HKD2_k127_5232613_13 HAF family - - - 0.00000000000000000000000008711 123.0
HKD2_k127_5232613_15 domain, Protein - - - 0.000002459 61.0
HKD2_k127_5232613_16 WD40-like Beta Propeller Repeat - - - 0.000002527 59.0
HKD2_k127_5232613_17 PQQ-like domain K17713 - - 0.00008227 55.0
HKD2_k127_5232613_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 7.2e-202 637.0
HKD2_k127_5232613_3 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 490.0
HKD2_k127_5232613_4 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 499.0
HKD2_k127_5232613_5 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 308.0
HKD2_k127_5232613_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 304.0
HKD2_k127_5232613_7 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000001191 249.0
HKD2_k127_5232613_8 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000001526 213.0
HKD2_k127_5232613_9 metallopeptidase activity K20276 - - 0.000000000000000000000000000000000000000000000001069 177.0
HKD2_k127_5253355_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 5.335e-267 837.0
HKD2_k127_5253355_1 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000002212 209.0
HKD2_k127_5253355_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000003254 166.0
HKD2_k127_5253355_3 - - - - 0.00000000000000000000000000000000000000005134 160.0
HKD2_k127_5253355_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000005579 66.0
HKD2_k127_5313153_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0 1392.0
HKD2_k127_5313153_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.092e-258 827.0
HKD2_k127_5313153_10 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000008676 228.0
HKD2_k127_5313153_11 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
HKD2_k127_5313153_12 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000002142 181.0
HKD2_k127_5313153_13 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000007847 170.0
HKD2_k127_5313153_14 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000001602 167.0
HKD2_k127_5313153_15 Pfam:TPM K08988 - - 0.000000000000000000000000000000003086 142.0
HKD2_k127_5313153_16 ABC-2 type transporter K01992 - - 0.000000000000000000000000009794 126.0
HKD2_k127_5313153_18 Dodecin K09165 - - 0.00000000000000000005683 93.0
HKD2_k127_5313153_19 Peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000006022 92.0
HKD2_k127_5313153_2 PFAM peptidase U34 dipeptidase - - - 2.268e-229 722.0
HKD2_k127_5313153_20 ABC-type multidrug transport system, permease component K01992 - - 0.00000001857 66.0
HKD2_k127_5313153_21 Water Stress and Hypersensitive response - - - 0.000007279 57.0
HKD2_k127_5313153_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 604.0
HKD2_k127_5313153_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 509.0
HKD2_k127_5313153_5 carbamoylphosphate synthase K01948,K11541 GO:0000050,GO:0000052,GO:0000096,GO:0000166,GO:0001101,GO:0001505,GO:0001889,GO:0002237,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0004175,GO:0005488,GO:0005509,GO:0005524,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006082,GO:0006508,GO:0006520,GO:0006525,GO:0006526,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0007494,GO:0008015,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008289,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009295,GO:0009410,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010243,GO:0014070,GO:0014074,GO:0014075,GO:0016020,GO:0016042,GO:0016053,GO:0016595,GO:0016597,GO:0016787,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0019240,GO:0019433,GO:0019538,GO:0019627,GO:0019637,GO:0019752,GO:0019866,GO:0030154,GO:0030554,GO:0030855,GO:0031090,GO:0031406,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032094,GO:0032496,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032991,GO:0033762,GO:0033993,GO:0034201,GO:0034641,GO:0035150,GO:0035295,GO:0035296,GO:0035639,GO:0036094,GO:0042133,GO:0042221,GO:0042311,GO:0042493,GO:0042592,GO:0042594,GO:0042645,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043200,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046209,GO:0046394,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0046683,GO:0046872,GO:0048513,GO:0048545,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0048878,GO:0050667,GO:0050801,GO:0050880,GO:0050896,GO:0051384,GO:0051591,GO:0051704,GO:0051707,GO:0051716,GO:0055081,GO:0055123,GO:0060416,GO:0060429,GO:0061008,GO:0065007,GO:0065008,GO:0070011,GO:0070013,GO:0070365,GO:0070408,GO:0070409,GO:0070542,GO:0070848,GO:0070887,GO:0071229,GO:0071310,GO:0071320,GO:0071363,GO:0071375,GO:0071377,GO:0071396,GO:0071398,GO:0071400,GO:0071407,GO:0071417,GO:0071495,GO:0071548,GO:0071704,GO:0071774,GO:0071941,GO:0072341,GO:0072593,GO:0090066,GO:0090407,GO:0097159,GO:0097237,GO:0097327,GO:0097367,GO:0097746,GO:0097755,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903717,GO:1903718,GO:2001057 2.1.3.2,6.3.4.16,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 403.0
HKD2_k127_5313153_6 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 387.0
HKD2_k127_5313153_7 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 355.0
HKD2_k127_5313153_8 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 329.0
HKD2_k127_5313153_9 COG1237 Metal-dependent hydrolases of the beta-lactamase superfamily II K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000006393 273.0
HKD2_k127_5356359_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1657.0
HKD2_k127_5356359_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 359.0
HKD2_k127_5356359_10 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000001974 71.0
HKD2_k127_5356359_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 325.0
HKD2_k127_5356359_3 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 303.0
HKD2_k127_5356359_4 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006571 282.0
HKD2_k127_5356359_5 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 271.0
HKD2_k127_5356359_6 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000002868 126.0
HKD2_k127_5356359_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000007735 123.0
HKD2_k127_5356359_8 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000004199 105.0
HKD2_k127_5356359_9 Tetratricopeptide repeat - - - 0.0000000006494 66.0
HKD2_k127_5368392_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 3.734e-309 953.0
HKD2_k127_5368392_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.894e-273 851.0
HKD2_k127_5368392_10 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 360.0
HKD2_k127_5368392_11 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 315.0
HKD2_k127_5368392_12 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 290.0
HKD2_k127_5368392_13 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002483 293.0
HKD2_k127_5368392_14 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000103 298.0
HKD2_k127_5368392_16 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000005706 244.0
HKD2_k127_5368392_17 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000003027 220.0
HKD2_k127_5368392_18 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000004434 207.0
HKD2_k127_5368392_19 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000003363 194.0
HKD2_k127_5368392_2 amino acid K03294 - - 3.658e-238 744.0
HKD2_k127_5368392_20 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000001697 190.0
HKD2_k127_5368392_21 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000004026 185.0
HKD2_k127_5368392_22 Sulfatase - - - 0.000000000000000000000000000000000000000009566 178.0
HKD2_k127_5368392_23 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000002224 145.0
HKD2_k127_5368392_24 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000008049 141.0
HKD2_k127_5368392_25 spore germination K03605 - - 0.000000000000000000000000000000001226 138.0
HKD2_k127_5368392_26 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000001412 132.0
HKD2_k127_5368392_27 ACT domain K09707 - - 0.0000000000000000000000000004147 126.0
HKD2_k127_5368392_28 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000005387 85.0
HKD2_k127_5368392_29 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.00002008 57.0
HKD2_k127_5368392_3 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 602.0
HKD2_k127_5368392_4 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 582.0
HKD2_k127_5368392_5 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 541.0
HKD2_k127_5368392_6 membrane K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 475.0
HKD2_k127_5368392_7 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 444.0
HKD2_k127_5368392_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 426.0
HKD2_k127_5368392_9 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 432.0
HKD2_k127_5435990_0 OPT oligopeptide transporter protein - - - 5.393e-246 778.0
HKD2_k127_5435990_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 612.0
HKD2_k127_5435990_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001454 248.0
HKD2_k127_5435990_11 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000002101 228.0
HKD2_k127_5435990_12 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000001492 238.0
HKD2_k127_5435990_14 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000001766 194.0
HKD2_k127_5435990_15 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000005966 168.0
HKD2_k127_5435990_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000002148 164.0
HKD2_k127_5435990_17 Nickel-containing superoxide dismutase K00518 - 1.15.1.1 0.0000000000000000000000000000000000000002539 155.0
HKD2_k127_5435990_18 TIGRFAM Diguanylate cyclase K21022 - 2.7.7.65 0.00000000000000000000000000000000000006607 158.0
HKD2_k127_5435990_19 Smr domain - - - 0.0000000000000000000000000001678 124.0
HKD2_k127_5435990_2 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 537.0
HKD2_k127_5435990_20 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000000007347 115.0
HKD2_k127_5435990_21 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000008047 125.0
HKD2_k127_5435990_22 overlaps another CDS with the same product name K16091 - - 0.0000000000000003964 88.0
HKD2_k127_5435990_23 Domain of unknown function (DUF4136) - - - 0.00000000000001134 85.0
HKD2_k127_5435990_24 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000007636 78.0
HKD2_k127_5435990_25 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 - - 0.0000000000001477 76.0
HKD2_k127_5435990_26 Protein of unknown function, DUF393 - - - 0.000000000000203 76.0
HKD2_k127_5435990_28 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000005756 52.0
HKD2_k127_5435990_29 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00004166 50.0
HKD2_k127_5435990_3 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 511.0
HKD2_k127_5435990_4 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 400.0
HKD2_k127_5435990_5 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 351.0
HKD2_k127_5435990_6 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 343.0
HKD2_k127_5435990_7 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002913 273.0
HKD2_k127_5435990_8 pfam chad - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001205 276.0
HKD2_k127_5435990_9 Cellulose biosynthesis protein BcsQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006003 250.0
HKD2_k127_5516375_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 1.168e-219 701.0
HKD2_k127_5516375_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 2.662e-210 688.0
HKD2_k127_5516375_2 Belongs to the thiolase family K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 561.0
HKD2_k127_5516375_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 403.0
HKD2_k127_5516375_4 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 387.0
HKD2_k127_5516375_5 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 379.0
HKD2_k127_5516375_6 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 297.0
HKD2_k127_5516375_7 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0002172 51.0
HKD2_k127_5683076_0 Identical to many other M. tuberculosis IS6110 transposase subunits. The transposase described here may be made by a frame shifting mechanism during translation that fuses K07497 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 337.0
HKD2_k127_5683076_1 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000005557 139.0
HKD2_k127_5683076_2 HTH-like domain K07497 - - 0.0000000000000000000003424 104.0
HKD2_k127_5683076_3 PFAM Transposase IS3 IS911family K07483 - - 0.00000000000000000004326 93.0
HKD2_k127_5683076_4 Evidence 2b Function of strongly homologous gene - - - 0.000000001951 62.0
HKD2_k127_5705405_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 7.019e-275 869.0
HKD2_k127_5705405_1 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 2.398e-223 704.0
HKD2_k127_5705405_10 - - - - 0.00000000000000000000000000000000000000000000000000003452 200.0
HKD2_k127_5705405_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000033 162.0
HKD2_k127_5705405_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000454 143.0
HKD2_k127_5705405_13 nuclease activity K06218 - - 0.000000000000000000000000000006548 123.0
HKD2_k127_5705405_14 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000001162 115.0
HKD2_k127_5705405_15 Belongs to the peptidase S8 family - - - 0.0000000000000000007517 99.0
HKD2_k127_5705405_16 COG1228 Imidazolonepropionase and related - - - 0.000000000000001165 91.0
HKD2_k127_5705405_17 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000005289 74.0
HKD2_k127_5705405_18 beta-lactamase domain protein K05555 - - 0.000000000008315 79.0
HKD2_k127_5705405_19 Clostripain family - - - 0.0000000862 64.0
HKD2_k127_5705405_2 belongs to the aldehyde dehydrogenase family - - - 2.438e-214 682.0
HKD2_k127_5705405_20 - - - - 0.000001967 53.0
HKD2_k127_5705405_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 512.0
HKD2_k127_5705405_4 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 499.0
HKD2_k127_5705405_5 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 356.0
HKD2_k127_5705405_6 OmpA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 335.0
HKD2_k127_5705405_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 306.0
HKD2_k127_5705405_8 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000001821 233.0
HKD2_k127_5705405_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001136 194.0
HKD2_k127_5714422_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1269.0
HKD2_k127_5714422_1 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1052.0
HKD2_k127_5714422_10 peptidase M36 K01417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 384.0
HKD2_k127_5714422_11 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 358.0
HKD2_k127_5714422_12 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD2_k127_5714422_13 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000943 283.0
HKD2_k127_5714422_14 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002802 261.0
HKD2_k127_5714422_15 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001793 268.0
HKD2_k127_5714422_16 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000002421 266.0
HKD2_k127_5714422_17 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000005273 241.0
HKD2_k127_5714422_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000004267 233.0
HKD2_k127_5714422_19 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000001516 220.0
HKD2_k127_5714422_2 Oligopeptide transporter OPT - - - 1.143e-246 786.0
HKD2_k127_5714422_20 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000303 184.0
HKD2_k127_5714422_21 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000005739 180.0
HKD2_k127_5714422_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000001115 162.0
HKD2_k127_5714422_23 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000001539 158.0
HKD2_k127_5714422_24 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000007965 156.0
HKD2_k127_5714422_25 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000003716 138.0
HKD2_k127_5714422_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000008381 113.0
HKD2_k127_5714422_27 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000007611 94.0
HKD2_k127_5714422_28 Autotransporter beta-domain K12678 - - 0.0001032 55.0
HKD2_k127_5714422_3 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 5.026e-206 678.0
HKD2_k127_5714422_30 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0002922 49.0
HKD2_k127_5714422_31 lipolytic protein G-D-S-L family - - - 0.0007881 51.0
HKD2_k127_5714422_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 538.0
HKD2_k127_5714422_5 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 462.0
HKD2_k127_5714422_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 399.0
HKD2_k127_5714422_7 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 388.0
HKD2_k127_5714422_8 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 371.0
HKD2_k127_5714422_9 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 368.0
HKD2_k127_5746934_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.562e-210 662.0
HKD2_k127_5746934_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005785 273.0
HKD2_k127_5757818_0 - - - - 0.0000000001896 71.0
HKD2_k127_5757818_1 COG3209 Rhs family protein - - - 0.00000004907 68.0
HKD2_k127_5778312_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1747.0
HKD2_k127_5778312_1 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 1.549e-253 835.0
HKD2_k127_5778312_10 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000001121 120.0
HKD2_k127_5778312_11 aldo keto reductase - - - 0.0000000000000000001648 101.0
HKD2_k127_5778312_12 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000008412 79.0
HKD2_k127_5778312_13 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000008358 63.0
HKD2_k127_5778312_15 4Fe-4S binding domain - - - 0.00001524 58.0
HKD2_k127_5778312_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 469.0
HKD2_k127_5778312_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 466.0
HKD2_k127_5778312_4 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 470.0
HKD2_k127_5778312_5 NADP-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 394.0
HKD2_k127_5778312_6 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
HKD2_k127_5778312_7 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002045 283.0
HKD2_k127_5778312_8 - - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
HKD2_k127_5778312_9 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000256 171.0
HKD2_k127_5877596_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.848e-252 801.0
HKD2_k127_5877596_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 535.0
HKD2_k127_5877596_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000723 210.0
HKD2_k127_5932790_0 Glycosyl hydrolase family 9 - - - 4.229e-217 707.0
HKD2_k127_5932790_1 Phospholipase_D-nuclease N-terminal K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 537.0
HKD2_k127_5932790_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.00000000000000000000000000000000000000000000002555 193.0
HKD2_k127_5932790_11 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000002001 193.0
HKD2_k127_5932790_12 ABC transporter K16786,K16787 - - 0.000000000000000000000000000000000000000000003808 181.0
HKD2_k127_5932790_13 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000000000000001561 157.0
HKD2_k127_5932790_14 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000005053 136.0
HKD2_k127_5932790_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000906 125.0
HKD2_k127_5932790_16 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000002903 91.0
HKD2_k127_5932790_17 - - - - 0.0000000000000241 87.0
HKD2_k127_5932790_18 Protein of unknown function (DUF1648) - - - 0.00000000000005183 83.0
HKD2_k127_5932790_19 Peptidase family M28 K05994 - 3.4.11.10 0.000000000009353 79.0
HKD2_k127_5932790_2 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 463.0
HKD2_k127_5932790_20 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000003411 70.0
HKD2_k127_5932790_21 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000001196 67.0
HKD2_k127_5932790_22 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00001705 54.0
HKD2_k127_5932790_23 Peptidase family M28 - - - 0.00003026 58.0
HKD2_k127_5932790_3 Domain of unknown function (DUF5009) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 339.0
HKD2_k127_5932790_4 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 336.0
HKD2_k127_5932790_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 311.0
HKD2_k127_5932790_6 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002114 278.0
HKD2_k127_5932790_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001699 270.0
HKD2_k127_5932790_8 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000002255 227.0
HKD2_k127_5932790_9 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000003166 226.0
HKD2_k127_6005067_0 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 463.0
HKD2_k127_6005067_1 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 455.0
HKD2_k127_6005067_10 PFAM Bacterial regulatory protein, Fis family K10941 - - 0.00000000000000000000000000004228 136.0
HKD2_k127_6005067_11 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000003337 118.0
HKD2_k127_6005067_12 protein tyrosine phosphatase activity K01104,K19302 - 3.1.3.48,3.6.1.27 0.0000000000000002279 92.0
HKD2_k127_6005067_13 - - - - 0.00000000000005456 85.0
HKD2_k127_6005067_14 Protein of unknown function (DUF3108) - - - 0.00000000009804 72.0
HKD2_k127_6005067_15 EamA-like transporter family - - - 0.00000008666 64.0
HKD2_k127_6005067_16 ubiE/COQ5 methyltransferase family - - - 0.0000008008 61.0
HKD2_k127_6005067_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K02528,K16924 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.1.1.182,2.7.1.148 0.000004449 53.0
HKD2_k127_6005067_18 cyclic nucleotide binding K07003 - - 0.00001529 59.0
HKD2_k127_6005067_2 esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 390.0
HKD2_k127_6005067_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 379.0
HKD2_k127_6005067_4 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 282.0
HKD2_k127_6005067_5 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000004648 253.0
HKD2_k127_6005067_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000002768 244.0
HKD2_k127_6005067_7 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000001133 210.0
HKD2_k127_6005067_8 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000038 219.0
HKD2_k127_6005067_9 Domain of unknown function (DUF1820) - - - 0.00000000000000000000000000000000001723 138.0
HKD2_k127_6068812_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 495.0
HKD2_k127_6068812_1 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 440.0
HKD2_k127_6068812_10 Formylmethanofuran dehydrogenase, subunit e K01239,K01250,K11261 - 1.2.7.12,3.2.2.1 0.00000000000000000000000000000000000005404 162.0
HKD2_k127_6068812_11 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000004116 147.0
HKD2_k127_6068812_12 23S rRNA-intervening sequence protein - - - 0.000000000000000000000001094 107.0
HKD2_k127_6068812_13 COG0095 Lipoate-protein ligase A K03800 - 6.3.1.20 0.00000000005806 73.0
HKD2_k127_6068812_14 O-antigen ligase - - - 0.00003317 57.0
HKD2_k127_6068812_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 431.0
HKD2_k127_6068812_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 365.0
HKD2_k127_6068812_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 361.0
HKD2_k127_6068812_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 349.0
HKD2_k127_6068812_6 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 344.0
HKD2_k127_6068812_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000006002 213.0
HKD2_k127_6068812_8 transferase activity, transferring glycosyl groups K13659 - 2.4.1.264 0.00000000000000000000000000000000000000000000000000002456 205.0
HKD2_k127_6068812_9 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000003478 194.0
HKD2_k127_6189515_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 396.0
HKD2_k127_6189515_1 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009657 300.0
HKD2_k127_6189515_2 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000206 160.0
HKD2_k127_6189515_3 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.00000001147 69.0
HKD2_k127_628651_0 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 616.0
HKD2_k127_628651_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 369.0
HKD2_k127_628651_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002755 279.0
HKD2_k127_628651_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000882 138.0
HKD2_k127_628651_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000002763 70.0
HKD2_k127_628651_5 Domain of unknown function (DUF2341) - - - 0.000000000009179 79.0
HKD2_k127_629843_0 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 1.159e-270 865.0
HKD2_k127_629843_1 Polysulphide reductase K00185 - - 2.38e-213 679.0
HKD2_k127_629843_10 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 324.0
HKD2_k127_629843_11 nucleotidase K01082 GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0003824,GO:0004441,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009628,GO:0009651,GO:0009987,GO:0016053,GO:0016311,GO:0016312,GO:0016787,GO:0016788,GO:0016791,GO:0019752,GO:0023052,GO:0035556,GO:0042538,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046030,GO:0046394,GO:0048015,GO:0048017,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052829,GO:0065007,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001228 281.0
HKD2_k127_629843_12 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009457 285.0
HKD2_k127_629843_13 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001179 264.0
HKD2_k127_629843_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000135 261.0
HKD2_k127_629843_15 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000008768 228.0
HKD2_k127_629843_16 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000002187 237.0
HKD2_k127_629843_17 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000001038 179.0
HKD2_k127_629843_18 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000006017 192.0
HKD2_k127_629843_19 - - - - 0.0000000000000000000000000000000000000009142 160.0
HKD2_k127_629843_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 625.0
HKD2_k127_629843_20 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000004597 166.0
HKD2_k127_629843_21 methyltransferase - - - 0.000000000000000000000000000000000000709 151.0
HKD2_k127_629843_22 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000002755 115.0
HKD2_k127_629843_23 cell septum assembly - - - 0.0000000000000000000002317 112.0
HKD2_k127_629843_24 - - - - 0.00000000000000003612 91.0
HKD2_k127_629843_25 serine-type endopeptidase activity K14645,K20276 - - 0.000000000000004127 89.0
HKD2_k127_629843_27 - - - - 0.0000002202 62.0
HKD2_k127_629843_28 Tetratricopeptide repeat - - - 0.000808 51.0
HKD2_k127_629843_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 608.0
HKD2_k127_629843_4 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 509.0
HKD2_k127_629843_5 Peptide transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 518.0
HKD2_k127_629843_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 444.0
HKD2_k127_629843_7 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 444.0
HKD2_k127_629843_8 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 350.0
HKD2_k127_629843_9 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 320.0
HKD2_k127_6384089_0 Domain of unknown function (DUF1846) - - - 4.777e-210 664.0
HKD2_k127_6384089_1 Belongs to the RtcB family K14415 - 6.5.1.3 3.523e-204 646.0
HKD2_k127_6384089_10 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001522 263.0
HKD2_k127_6384089_11 GTP binding K06883 - - 0.000000000000000000000000000000000000000000000000000000000000001164 244.0
HKD2_k127_6384089_12 serine-type endopeptidase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000002985 236.0
HKD2_k127_6384089_13 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000001998 234.0
HKD2_k127_6384089_14 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000005359 221.0
HKD2_k127_6384089_15 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000001812 219.0
HKD2_k127_6384089_17 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000005028 154.0
HKD2_k127_6384089_18 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000001674 143.0
HKD2_k127_6384089_19 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000004173 132.0
HKD2_k127_6384089_2 Protein of unknown function (DUF2867) - - - 4.661e-195 630.0
HKD2_k127_6384089_20 COG3209 Rhs family protein - - - 0.0000000000000000000002814 111.0
HKD2_k127_6384089_22 Regulatory protein - - - 0.00000000000000001591 89.0
HKD2_k127_6384089_23 - - - - 0.0000000333 59.0
HKD2_k127_6384089_3 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 591.0
HKD2_k127_6384089_4 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 463.0
HKD2_k127_6384089_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 449.0
HKD2_k127_6384089_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 401.0
HKD2_k127_6384089_7 NADH dehydrogenase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 389.0
HKD2_k127_6384089_8 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 387.0
HKD2_k127_6384089_9 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 321.0
HKD2_k127_6399360_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 539.0
HKD2_k127_6399360_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 516.0
HKD2_k127_6399360_10 PFAM AIG2 family protein - - - 0.000008018 58.0
HKD2_k127_6399360_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0005823 53.0
HKD2_k127_6399360_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
HKD2_k127_6399360_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001991 261.0
HKD2_k127_6399360_4 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000005061 232.0
HKD2_k127_6399360_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000003889 205.0
HKD2_k127_6399360_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000005918 146.0
HKD2_k127_6399360_7 Transcriptional regulator - - - 0.0000000000000000001627 101.0
HKD2_k127_6399360_8 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000007199 77.0
HKD2_k127_6399360_9 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000008269 66.0
HKD2_k127_6509905_0 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 2.14e-317 993.0
HKD2_k127_6509905_1 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 459.0
HKD2_k127_6509905_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 372.0
HKD2_k127_6509905_3 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 349.0
HKD2_k127_6509905_4 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 309.0
HKD2_k127_6509905_5 GHMP kinases N terminal domain K00938 - 2.7.4.2 0.00000000000000000000000000000000000000000000000000000000000005279 237.0
HKD2_k127_6509905_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000001371 219.0
HKD2_k127_6509905_7 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000007917 186.0
HKD2_k127_6535541_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 523.0
HKD2_k127_6535541_1 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 370.0
HKD2_k127_6535541_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 370.0
HKD2_k127_6535541_3 short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000004199 222.0
HKD2_k127_6535541_4 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000003013 66.0
HKD2_k127_6542722_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 579.0
HKD2_k127_6542722_1 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000000001625 160.0
HKD2_k127_6542722_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000001216 71.0
HKD2_k127_6547342_0 AMP-binding enzyme K01897 - 6.2.1.3 4.065e-263 826.0
HKD2_k127_6547342_1 acyl-CoA dehydrogenase - - - 8.084e-250 784.0
HKD2_k127_6547342_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000001912 210.0
HKD2_k127_6547342_11 Protein of unknown function (DUF3696) - - - 0.000000000000000000000000000000000000000000000000004837 207.0
HKD2_k127_6547342_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000629 187.0
HKD2_k127_6547342_13 transcriptional regulator - - - 0.0000000000000000000000000000000004865 140.0
HKD2_k127_6547342_14 Methyltransferase domain - - - 0.000000000000000000000000000009107 128.0
HKD2_k127_6547342_15 Peptidase family M23 - - - 0.00000000000000000000000001147 124.0
HKD2_k127_6547342_16 Nucleotidyl transferase - - - 0.000000000000000000002781 100.0
HKD2_k127_6547342_17 PFAM response regulator receiver - - - 0.000001122 58.0
HKD2_k127_6547342_18 Concanavalin A-like lectin/glucanases superfamily - - - 0.00005668 57.0
HKD2_k127_6547342_2 4Fe-4S binding domain - - - 5.434e-194 613.0
HKD2_k127_6547342_3 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 446.0
HKD2_k127_6547342_4 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 437.0
HKD2_k127_6547342_5 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 407.0
HKD2_k127_6547342_6 response regulator K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 386.0
HKD2_k127_6547342_7 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
HKD2_k127_6547342_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 295.0
HKD2_k127_6547342_9 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
HKD2_k127_6610034_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 1.11e-303 947.0
HKD2_k127_6610034_1 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 524.0
HKD2_k127_6610034_10 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000001208 180.0
HKD2_k127_6610034_11 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000004563 167.0
HKD2_k127_6610034_12 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000003136 168.0
HKD2_k127_6610034_13 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000000000000006599 153.0
HKD2_k127_6610034_14 BMC K04025 - - 0.000000000000000000000000000000003022 136.0
HKD2_k127_6610034_15 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000001145 123.0
HKD2_k127_6610034_16 Thioredoxin-like - - - 0.00000000000000000000000000007044 123.0
HKD2_k127_6610034_17 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000002199 91.0
HKD2_k127_6610034_18 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.00000000000000000613 99.0
HKD2_k127_6610034_19 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000007111 81.0
HKD2_k127_6610034_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 455.0
HKD2_k127_6610034_20 Stigma-specific protein, Stig1 - - - 0.000000001555 70.0
HKD2_k127_6610034_21 - - - - 0.0000001526 62.0
HKD2_k127_6610034_22 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000003954 62.0
HKD2_k127_6610034_23 COG2931, RTX toxins and related Ca2 -binding proteins K01127 - 3.1.4.50 0.00003467 57.0
HKD2_k127_6610034_3 Aldehyde dehydrogenase family K04021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 458.0
HKD2_k127_6610034_4 PFAM BMC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 312.0
HKD2_k127_6610034_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 308.0
HKD2_k127_6610034_6 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002307 289.0
HKD2_k127_6610034_7 deoxyribose-phosphate aldolase activity K00852,K01619,K01840,K01844 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004487 269.0
HKD2_k127_6610034_8 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000492 212.0
HKD2_k127_6610034_9 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000002086 190.0
HKD2_k127_6700538_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.265e-225 709.0
HKD2_k127_6700538_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 565.0
HKD2_k127_6700538_10 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001147 291.0
HKD2_k127_6700538_11 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
HKD2_k127_6700538_12 PFAM Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000004634 237.0
HKD2_k127_6700538_13 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000001872 241.0
HKD2_k127_6700538_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000002006 228.0
HKD2_k127_6700538_15 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000001825 216.0
HKD2_k127_6700538_16 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000004779 210.0
HKD2_k127_6700538_17 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000007453 195.0
HKD2_k127_6700538_18 histidyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000001865 186.0
HKD2_k127_6700538_19 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000005909 176.0
HKD2_k127_6700538_2 Fumarylacetoacetase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 547.0
HKD2_k127_6700538_20 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000001169 154.0
HKD2_k127_6700538_21 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000001776 149.0
HKD2_k127_6700538_22 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000554 137.0
HKD2_k127_6700538_23 transcriptional regulator K16137 - - 0.0000000000000000000000000000002866 131.0
HKD2_k127_6700538_24 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000004622 130.0
HKD2_k127_6700538_25 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000002719 108.0
HKD2_k127_6700538_26 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000716 108.0
HKD2_k127_6700538_27 CarboxypepD_reg-like domain K13276 - - 0.0000000000000001485 95.0
HKD2_k127_6700538_28 outer membrane efflux protein - - - 0.0000000008542 71.0
HKD2_k127_6700538_3 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 557.0
HKD2_k127_6700538_4 CBS domain containing protein K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 510.0
HKD2_k127_6700538_5 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 423.0
HKD2_k127_6700538_6 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 366.0
HKD2_k127_6700538_7 Domain of unknown function (DUF3471) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 347.0
HKD2_k127_6700538_8 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 322.0
HKD2_k127_6700538_9 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 311.0
HKD2_k127_6708014_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000006745 89.0
HKD2_k127_6708014_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000005472 81.0
HKD2_k127_6708014_2 Glycosyl transferase 4-like - - - 0.00000000004446 75.0
HKD2_k127_6819764_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.734e-281 892.0
HKD2_k127_6819764_1 Beta-eliminating lyase K01667 - 4.1.99.1 7.746e-236 737.0
HKD2_k127_6819764_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 308.0
HKD2_k127_6819764_11 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 311.0
HKD2_k127_6819764_12 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
HKD2_k127_6819764_13 Belongs to the SEDS family. MrdB RodA subfamily K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000004738 244.0
HKD2_k127_6819764_14 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000006623 252.0
HKD2_k127_6819764_15 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000001167 168.0
HKD2_k127_6819764_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000001011 168.0
HKD2_k127_6819764_17 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000009916 167.0
HKD2_k127_6819764_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000001007 170.0
HKD2_k127_6819764_19 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000001413 158.0
HKD2_k127_6819764_2 belongs to the CobB CobQ family K00625,K13788 - 2.3.1.8 1.455e-226 723.0
HKD2_k127_6819764_20 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000002639 160.0
HKD2_k127_6819764_21 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000004996 160.0
HKD2_k127_6819764_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000167 147.0
HKD2_k127_6819764_23 lipid kinase, YegS Rv2252 BmrU family - - - 0.000000000000000000000000000000000293 150.0
HKD2_k127_6819764_24 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000005128 126.0
HKD2_k127_6819764_25 STAS domain K04749 - - 0.0000000000000000000000000000004637 125.0
HKD2_k127_6819764_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000008333 119.0
HKD2_k127_6819764_27 - - - - 0.00000000000000000000000001069 119.0
HKD2_k127_6819764_28 Hfq protein - - - 0.00000000000000000000000001367 115.0
HKD2_k127_6819764_29 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000009099 112.0
HKD2_k127_6819764_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 612.0
HKD2_k127_6819764_30 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000009021 104.0
HKD2_k127_6819764_31 Competence protein - - - 0.0000000000000000004382 98.0
HKD2_k127_6819764_32 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.000000000000000001297 96.0
HKD2_k127_6819764_33 peptidyl-tyrosine sulfation - - - 0.000000000000001596 89.0
HKD2_k127_6819764_34 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000004512 65.0
HKD2_k127_6819764_35 FecR protein - - - 0.000001193 61.0
HKD2_k127_6819764_36 iron ion homeostasis K07165 - - 0.00005912 55.0
HKD2_k127_6819764_37 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0002806 51.0
HKD2_k127_6819764_38 Domain of unknown function (DUF4388) - - - 0.0003598 53.0
HKD2_k127_6819764_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 522.0
HKD2_k127_6819764_5 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 501.0
HKD2_k127_6819764_6 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 452.0
HKD2_k127_6819764_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 435.0
HKD2_k127_6819764_8 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 421.0
HKD2_k127_6819764_9 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 390.0
HKD2_k127_6822615_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.194e-224 711.0
HKD2_k127_6822615_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
HKD2_k127_6827132_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 620.0
HKD2_k127_6827132_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 610.0
HKD2_k127_6827132_10 tryptophan K00500 GO:0000003,GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0004510,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006464,GO:0006520,GO:0006558,GO:0006559,GO:0006568,GO:0006569,GO:0006570,GO:0006571,GO:0006576,GO:0006582,GO:0006584,GO:0006586,GO:0006725,GO:0006726,GO:0006732,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0008150,GO:0008152,GO:0008340,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009073,GO:0009074,GO:0009095,GO:0009308,GO:0009310,GO:0009712,GO:0009713,GO:0009987,GO:0010259,GO:0016053,GO:0016054,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017144,GO:0018126,GO:0018958,GO:0019438,GO:0019439,GO:0019538,GO:0019748,GO:0019751,GO:0019752,GO:0031406,GO:0032501,GO:0032502,GO:0034311,GO:0034641,GO:0036094,GO:0036211,GO:0040002,GO:0042133,GO:0042136,GO:0042335,GO:0042402,GO:0042423,GO:0042430,GO:0042436,GO:0042438,GO:0042440,GO:0042441,GO:0042558,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043324,GO:0043412,GO:0043436,GO:0043473,GO:0043474,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046146,GO:0046148,GO:0046189,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0046983,GO:0048037,GO:0048066,GO:0048069,GO:0048856,GO:0050877,GO:0050890,GO:0050896,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901615,GO:1901617,GO:1902221,GO:1902222 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000001877 238.0
HKD2_k127_6827132_11 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000005021 234.0
HKD2_k127_6827132_12 - - - - 0.000000000000000000000000000000000000000000000000000000000004837 217.0
HKD2_k127_6827132_13 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
HKD2_k127_6827132_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000001586 195.0
HKD2_k127_6827132_15 DEAD DEAH box helicase K06877 - - 0.000000000000000000000000000000000000000000008724 180.0
HKD2_k127_6827132_16 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000003901 163.0
HKD2_k127_6827132_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000001599 161.0
HKD2_k127_6827132_18 HDOD domain - - - 0.0000000000000000000000000000001007 137.0
HKD2_k127_6827132_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000543 123.0
HKD2_k127_6827132_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 586.0
HKD2_k127_6827132_20 GYD domain - - - 0.00000000000000000000000006358 112.0
HKD2_k127_6827132_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000001357 117.0
HKD2_k127_6827132_22 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000009949 119.0
HKD2_k127_6827132_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000007072 96.0
HKD2_k127_6827132_24 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000001534 92.0
HKD2_k127_6827132_25 Rieske [2Fe-2S] domain - - - 0.000000000000000003913 99.0
HKD2_k127_6827132_26 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000004909 79.0
HKD2_k127_6827132_27 repeat-containing protein - - - 0.0000000002443 73.0
HKD2_k127_6827132_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 567.0
HKD2_k127_6827132_4 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 524.0
HKD2_k127_6827132_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 500.0
HKD2_k127_6827132_6 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 349.0
HKD2_k127_6827132_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 342.0
HKD2_k127_6827132_8 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 323.0
HKD2_k127_6827132_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 306.0
HKD2_k127_6896383_0 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 362.0
HKD2_k127_6896383_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 332.0
HKD2_k127_6896383_2 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000003482 112.0
HKD2_k127_6896383_3 Fimbrial assembly protein (PilN) K02663 - - 0.00000000002983 72.0
HKD2_k127_6896383_4 Ribosomal L28 family K02902 - - 0.0000004084 53.0
HKD2_k127_6896383_5 Pilus assembly protein, PilP K02665 - - 0.0003121 52.0
HKD2_k127_6908614_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1041.0
HKD2_k127_6908614_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 3.35e-218 683.0
HKD2_k127_6908614_10 Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 395.0
HKD2_k127_6908614_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 399.0
HKD2_k127_6908614_12 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 383.0
HKD2_k127_6908614_13 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HKD2_k127_6908614_14 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 361.0
HKD2_k127_6908614_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 323.0
HKD2_k127_6908614_16 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 323.0
HKD2_k127_6908614_17 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HKD2_k127_6908614_18 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
HKD2_k127_6908614_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 289.0
HKD2_k127_6908614_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738,K01912 - 2.5.1.47,6.2.1.30 1.686e-208 662.0
HKD2_k127_6908614_20 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007162 303.0
HKD2_k127_6908614_21 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000129 291.0
HKD2_k127_6908614_22 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001395 282.0
HKD2_k127_6908614_23 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005041 277.0
HKD2_k127_6908614_24 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007436 285.0
HKD2_k127_6908614_25 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007819 286.0
HKD2_k127_6908614_26 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002407 283.0
HKD2_k127_6908614_27 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000009441 269.0
HKD2_k127_6908614_28 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001706 284.0
HKD2_k127_6908614_29 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001411 256.0
HKD2_k127_6908614_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 1.456e-203 661.0
HKD2_k127_6908614_30 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007131 261.0
HKD2_k127_6908614_31 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000058 243.0
HKD2_k127_6908614_32 beta-lactamase domain protein K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000001084 241.0
HKD2_k127_6908614_33 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
HKD2_k127_6908614_34 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001024 244.0
HKD2_k127_6908614_35 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000006478 220.0
HKD2_k127_6908614_36 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000001005 210.0
HKD2_k127_6908614_37 sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000002346 212.0
HKD2_k127_6908614_38 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000003351 199.0
HKD2_k127_6908614_4 FAD dependent oxidoreductase - - - 5.186e-199 631.0
HKD2_k127_6908614_40 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000009574 189.0
HKD2_k127_6908614_41 Pseudouridylate K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000474 190.0
HKD2_k127_6908614_42 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000001436 190.0
HKD2_k127_6908614_43 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000001603 168.0
HKD2_k127_6908614_44 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000106 156.0
HKD2_k127_6908614_45 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000208 151.0
HKD2_k127_6908614_46 PFAM DsrE family protein K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000001215 142.0
HKD2_k127_6908614_47 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000008392 127.0
HKD2_k127_6908614_48 - - - - 0.0000000000000000000000000008191 119.0
HKD2_k127_6908614_49 transcription factor binding - - - 0.00000000000000000000000002179 119.0
HKD2_k127_6908614_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 499.0
HKD2_k127_6908614_50 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000006623 115.0
HKD2_k127_6908614_52 Thioredoxin-like - - - 0.0000000000000000000002538 104.0
HKD2_k127_6908614_53 phosphoglycolate phosphatase activity - - - 0.000000000000000000007638 104.0
HKD2_k127_6908614_54 Helix-turn-helix domain - - - 0.00000000000000000005902 101.0
HKD2_k127_6908614_55 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.0000000000000000001274 95.0
HKD2_k127_6908614_56 Serine aminopeptidase, S33 K16434 - - 0.0000000000000000003504 98.0
HKD2_k127_6908614_57 methyltransferase activity K00587 - 2.1.1.100 0.0000000000000006949 85.0
HKD2_k127_6908614_58 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.000000000000007198 83.0
HKD2_k127_6908614_59 - - - - 0.000000000000008026 84.0
HKD2_k127_6908614_6 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611,K09065 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
HKD2_k127_6908614_60 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000009749 83.0
HKD2_k127_6908614_61 Diguanylate cyclase - - - 0.000000000001514 78.0
HKD2_k127_6908614_62 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.000000000002994 80.0
HKD2_k127_6908614_63 SNARE associated Golgi protein - - - 0.00000000002151 64.0
HKD2_k127_6908614_64 protein conserved in bacteria - - - 0.00000000002634 76.0
HKD2_k127_6908614_65 PD-(D/E)XK nuclease superfamily - - - 0.00000000004365 77.0
HKD2_k127_6908614_66 TIGRFAM regulatory protein, FmdB - - - 0.00000000007862 68.0
HKD2_k127_6908614_67 PFAM von Willebrand factor type A K07114,K12511 - - 0.0000002161 64.0
HKD2_k127_6908614_68 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000002358 59.0
HKD2_k127_6908614_69 tetratricopeptide repeat - - - 0.000001087 61.0
HKD2_k127_6908614_7 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 440.0
HKD2_k127_6908614_8 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 416.0
HKD2_k127_6908614_9 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 402.0
HKD2_k127_7027115_0 NADH dehydrogenase (quinone) K00335 - 1.6.5.3 2.837e-241 761.0
HKD2_k127_7027115_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 551.0
HKD2_k127_7027115_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000894 192.0
HKD2_k127_7027115_11 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) K03320 - - 0.0000000000000000000000000000000000000000004013 177.0
HKD2_k127_7027115_12 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000003151 154.0
HKD2_k127_7027115_13 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000006584 159.0
HKD2_k127_7027115_14 bacterial-type flagellum organization - - - 0.0000000000000000000000000000000000001213 162.0
HKD2_k127_7027115_15 Acyl CoA binding protein - - - 0.0000000000000000000003414 106.0
HKD2_k127_7027115_16 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000002383 88.0
HKD2_k127_7027115_17 Psort location CytoplasmicMembrane, score - - - 0.000000000000002324 87.0
HKD2_k127_7027115_18 Ferritin-like domain - - - 0.00000000000102 77.0
HKD2_k127_7027115_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 523.0
HKD2_k127_7027115_3 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 535.0
HKD2_k127_7027115_4 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 449.0
HKD2_k127_7027115_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
HKD2_k127_7027115_6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 366.0
HKD2_k127_7027115_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000112 277.0
HKD2_k127_7027115_8 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000001493 214.0
HKD2_k127_7027115_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000002613 185.0
HKD2_k127_7144807_0 Cytochrome b subunit of formate dehydrogenase-like protein - - - 6.442e-238 754.0
HKD2_k127_7144807_1 CHASE2 domain protein - - - 3.535e-223 707.0
HKD2_k127_7144807_10 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001801 294.0
HKD2_k127_7144807_11 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000765 285.0
HKD2_k127_7144807_12 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004171 257.0
HKD2_k127_7144807_13 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001811 267.0
HKD2_k127_7144807_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000005744 262.0
HKD2_k127_7144807_15 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000652 269.0
HKD2_k127_7144807_16 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000435 230.0
HKD2_k127_7144807_17 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000001341 199.0
HKD2_k127_7144807_18 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000008119 162.0
HKD2_k127_7144807_19 PIN domain K07175 - - 0.00000000000000000000000000000000000017 158.0
HKD2_k127_7144807_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 493.0
HKD2_k127_7144807_20 domain, Protein K15125,K21449 - - 0.0000000000000000000000000002444 134.0
HKD2_k127_7144807_21 Transglycosylase SLT domain K08309 - - 0.00000000000000000000004679 115.0
HKD2_k127_7144807_22 nuclear chromosome segregation - - - 0.00000000000000008752 94.0
HKD2_k127_7144807_23 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000006976 79.0
HKD2_k127_7144807_24 PFAM NHL repeat containing protein - - - 0.00000000000001023 90.0
HKD2_k127_7144807_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000003829 61.0
HKD2_k127_7144807_26 C4-type zinc ribbon domain K07164 - - 0.000000004684 68.0
HKD2_k127_7144807_27 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000004674 53.0
HKD2_k127_7144807_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 401.0
HKD2_k127_7144807_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 405.0
HKD2_k127_7144807_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 396.0
HKD2_k127_7144807_6 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 359.0
HKD2_k127_7144807_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 359.0
HKD2_k127_7144807_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 329.0
HKD2_k127_7144807_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 307.0
HKD2_k127_7263595_0 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 520.0
HKD2_k127_7263595_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 267.0
HKD2_k127_7263595_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.0003547 46.0
HKD2_k127_7278318_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 374.0
HKD2_k127_7278318_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 367.0
HKD2_k127_7278318_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 348.0
HKD2_k127_7278318_3 Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006391 304.0
HKD2_k127_7278318_4 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000001302 203.0
HKD2_k127_7278318_5 FecR protein - - - 0.00000000000000000000000000000000000000000000001816 183.0
HKD2_k127_7278318_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000002689 152.0
HKD2_k127_7278318_7 - - - - 0.0000000000000000000000000000000001392 148.0
HKD2_k127_7278318_8 Protein of unknown function (DUF1298) - - - 0.0000000000000000003013 91.0
HKD2_k127_74702_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 582.0
HKD2_k127_74702_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 579.0
HKD2_k127_74702_2 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 327.0
HKD2_k127_74702_3 COG2863 Cytochrome c553 - - - 0.00000000000000000000000000000000000000000000000000000000000000001051 230.0
HKD2_k127_74702_4 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000393 153.0
HKD2_k127_74702_5 TIGRFAM Diguanylate cyclase K13590 - 2.7.7.65 0.0000006181 61.0
HKD2_k127_757882_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 467.0
HKD2_k127_757882_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 429.0
HKD2_k127_757882_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 428.0
HKD2_k127_757882_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 399.0
HKD2_k127_757882_4 PFAM HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 350.0
HKD2_k127_757882_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000009425 238.0
HKD2_k127_757882_6 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000008629 138.0
HKD2_k127_7683459_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1265.0
HKD2_k127_7683459_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 379.0
HKD2_k127_7683459_2 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 334.0
HKD2_k127_7683459_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 305.0
HKD2_k127_7683459_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004113 298.0
HKD2_k127_7683459_6 Fibronectin type III domain - - - 0.000000000000001714 90.0
HKD2_k127_7683459_7 Galactose oxidase, central domain - - - 0.000000002707 69.0
HKD2_k127_7683459_8 PFAM FecR protein K01179,K03933 - 3.2.1.4 0.00000006822 66.0
HKD2_k127_7683459_9 Galactose oxidase, central domain - - - 0.0000005918 61.0
HKD2_k127_7704609_0 elongation factor Tu domain 2 protein K06207 - - 3.679e-281 876.0
HKD2_k127_7704609_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000001467 160.0
HKD2_k127_7721210_0 Cellobiose phosphorylase K00702 - 2.4.1.20 0.0 1171.0
HKD2_k127_7721210_1 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 7.923e-275 874.0
HKD2_k127_7721210_10 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 439.0
HKD2_k127_7721210_11 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 422.0
HKD2_k127_7721210_12 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 423.0
HKD2_k127_7721210_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 434.0
HKD2_k127_7721210_14 hydrolase family 5 K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 404.0
HKD2_k127_7721210_15 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 369.0
HKD2_k127_7721210_16 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
HKD2_k127_7721210_17 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 365.0
HKD2_k127_7721210_18 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 326.0
HKD2_k127_7721210_19 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 316.0
HKD2_k127_7721210_2 Heat shock 70 kDa protein K04043 - - 9.692e-232 732.0
HKD2_k127_7721210_20 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 307.0
HKD2_k127_7721210_21 Lamin Tail Domain K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008296 294.0
HKD2_k127_7721210_22 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001229 276.0
HKD2_k127_7721210_23 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001398 267.0
HKD2_k127_7721210_24 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 269.0
HKD2_k127_7721210_25 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003856 263.0
HKD2_k127_7721210_26 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000002057 249.0
HKD2_k127_7721210_27 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000005641 242.0
HKD2_k127_7721210_28 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000004242 227.0
HKD2_k127_7721210_29 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000003352 223.0
HKD2_k127_7721210_3 ABC transporter, ATP-binding protein - - - 1.79e-226 721.0
HKD2_k127_7721210_30 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000002259 221.0
HKD2_k127_7721210_31 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000007893 207.0
HKD2_k127_7721210_32 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000002352 203.0
HKD2_k127_7721210_33 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000001128 188.0
HKD2_k127_7721210_34 hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000017 191.0
HKD2_k127_7721210_36 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000001542 186.0
HKD2_k127_7721210_37 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000002732 184.0
HKD2_k127_7721210_38 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000001184 178.0
HKD2_k127_7721210_39 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001083 171.0
HKD2_k127_7721210_4 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.432e-210 668.0
HKD2_k127_7721210_40 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000005703 152.0
HKD2_k127_7721210_41 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000004169 136.0
HKD2_k127_7721210_42 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000003377 142.0
HKD2_k127_7721210_43 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000004164 139.0
HKD2_k127_7721210_44 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000003324 129.0
HKD2_k127_7721210_45 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000001837 122.0
HKD2_k127_7721210_46 glycosyl transferase - - - 0.0000000000000000000000007329 116.0
HKD2_k127_7721210_47 Tellurite resistance protein TerB - - - 0.000000000001688 74.0
HKD2_k127_7721210_48 RESPONSE REGULATOR receiver - - - 0.00000000009635 73.0
HKD2_k127_7721210_49 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000204 72.0
HKD2_k127_7721210_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 2.473e-195 620.0
HKD2_k127_7721210_50 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001585 71.0
HKD2_k127_7721210_51 PFAM Tetratricopeptide repeat - - - 0.00000002368 66.0
HKD2_k127_7721210_52 PFAM PEGA domain - - - 0.00000684 57.0
HKD2_k127_7721210_53 transcriptional regulator - - - 0.0001761 52.0
HKD2_k127_7721210_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 613.0
HKD2_k127_7721210_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 550.0
HKD2_k127_7721210_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 542.0
HKD2_k127_7721210_9 Glycosyl hydrolase family 20, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 486.0
HKD2_k127_7796348_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 476.0
HKD2_k127_7796348_1 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 463.0
HKD2_k127_7796348_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 457.0
HKD2_k127_7796348_3 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001579 261.0
HKD2_k127_7796348_4 RmlD substrate binding domain K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000002443 248.0
HKD2_k127_7796348_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000001537 250.0
HKD2_k127_7796348_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000002878 195.0
HKD2_k127_7796348_7 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000001363 153.0
HKD2_k127_7796348_8 HAT (Half-A-TPR) repeats K12855 - - 0.0001026 55.0
HKD2_k127_7844638_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 1.18e-196 634.0
HKD2_k127_7844638_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 583.0
HKD2_k127_7844638_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 300.0
HKD2_k127_7844638_11 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 284.0
HKD2_k127_7844638_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000005517 265.0
HKD2_k127_7844638_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007226 267.0
HKD2_k127_7844638_14 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
HKD2_k127_7844638_15 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000008712 209.0
HKD2_k127_7844638_16 - - - - 0.000000000000000000000000000000000000000000000000000007624 211.0
HKD2_k127_7844638_17 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000863 198.0
HKD2_k127_7844638_18 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000002224 200.0
HKD2_k127_7844638_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000006601 180.0
HKD2_k127_7844638_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 498.0
HKD2_k127_7844638_20 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000002285 193.0
HKD2_k127_7844638_21 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000004415 177.0
HKD2_k127_7844638_22 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000001131 177.0
HKD2_k127_7844638_23 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000000000000007301 164.0
HKD2_k127_7844638_24 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000005251 167.0
HKD2_k127_7844638_25 deoxyribonuclease V activity K01144,K05982 - 3.1.11.5,3.1.21.7 0.000000000000000000000000000000000000007054 151.0
HKD2_k127_7844638_26 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000007469 149.0
HKD2_k127_7844638_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000007924 141.0
HKD2_k127_7844638_28 pfam abc K09691 - - 0.00000000000000000000000000001714 125.0
HKD2_k127_7844638_29 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000006354 126.0
HKD2_k127_7844638_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 456.0
HKD2_k127_7844638_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000002385 115.0
HKD2_k127_7844638_31 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000004685 118.0
HKD2_k127_7844638_32 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000007175 108.0
HKD2_k127_7844638_33 oxidoreductase activity - - - 0.00000000000000000000008475 114.0
HKD2_k127_7844638_34 - - - - 0.000000000000000001217 96.0
HKD2_k127_7844638_35 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000004326 97.0
HKD2_k127_7844638_36 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000857 94.0
HKD2_k127_7844638_37 domain, Protein - - - 0.00000000000000005488 98.0
HKD2_k127_7844638_38 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000002181 77.0
HKD2_k127_7844638_39 Transport permease protein K09690 - - 0.00000000000004429 83.0
HKD2_k127_7844638_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 416.0
HKD2_k127_7844638_40 S-layer homology domain - - - 0.0000000000004199 82.0
HKD2_k127_7844638_41 Sporulation and spore germination - - - 0.000000000002578 77.0
HKD2_k127_7844638_42 PFAM Cyclic nucleotide-binding - - - 0.000000000003178 79.0
HKD2_k127_7844638_43 PIN domain - - - 0.00000001133 61.0
HKD2_k127_7844638_44 - - - - 0.00000009445 53.0
HKD2_k127_7844638_45 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000103 65.0
HKD2_k127_7844638_46 Family of unknown function (DUF1028) - - - 0.00000156 60.0
HKD2_k127_7844638_47 - - - - 0.000003566 55.0
HKD2_k127_7844638_48 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001769 49.0
HKD2_k127_7844638_49 Helix-turn-helix domain - - - 0.0001866 50.0
HKD2_k127_7844638_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 395.0
HKD2_k127_7844638_50 Phage related protein - - - 0.0002643 43.0
HKD2_k127_7844638_51 DNA-binding transcriptional activator of the SARP family - - - 0.0008306 51.0
HKD2_k127_7844638_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 377.0
HKD2_k127_7844638_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 352.0
HKD2_k127_7844638_8 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 309.0
HKD2_k127_7844638_9 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 319.0
HKD2_k127_7900287_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 4.274e-321 1002.0
HKD2_k127_7900287_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 624.0
HKD2_k127_7900287_10 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000001976 229.0
HKD2_k127_7900287_11 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000004556 226.0
HKD2_k127_7900287_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000002702 226.0
HKD2_k127_7900287_13 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000007948 228.0
HKD2_k127_7900287_14 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000004854 199.0
HKD2_k127_7900287_15 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18590 - 1.5.1.3 0.0000000000000000000000000000000000000000000000217 179.0
HKD2_k127_7900287_16 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000008581 163.0
HKD2_k127_7900287_17 Outer membrane protein beta-barrel family K16087,K16092 - - 0.000000000000000000000000000000005827 148.0
HKD2_k127_7900287_18 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000005448 120.0
HKD2_k127_7900287_19 L-fuculose phosphate aldolase K01628 - 4.1.2.17 0.00000000000000000001571 99.0
HKD2_k127_7900287_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 625.0
HKD2_k127_7900287_20 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000003884 100.0
HKD2_k127_7900287_21 Protein of unknown function (DUF2892) - - - 0.0000000000000000009363 87.0
HKD2_k127_7900287_22 Lipopolysaccharide-assembly - - - 0.000000000000000001241 98.0
HKD2_k127_7900287_23 Belongs to the peptidase S1B family K01337 - 3.4.21.50 0.0000000000000405 87.0
HKD2_k127_7900287_24 Domain of unknown function (DUF4126) - - - 0.00000000002909 74.0
HKD2_k127_7900287_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000001561 61.0
HKD2_k127_7900287_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 594.0
HKD2_k127_7900287_4 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 474.0
HKD2_k127_7900287_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 442.0
HKD2_k127_7900287_6 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 437.0
HKD2_k127_7900287_7 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 391.0
HKD2_k127_7900287_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
HKD2_k127_7900287_9 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 309.0
HKD2_k127_7912205_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000269 230.0
HKD2_k127_7912205_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000007794 151.0
HKD2_k127_7912479_0 Prolyl oligopeptidase K01322 - 3.4.21.26 2.569e-242 769.0
HKD2_k127_7912479_1 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 348.0
HKD2_k127_7912479_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003507 282.0
HKD2_k127_7912479_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004586 233.0
HKD2_k127_7912479_4 Peptidase family S41 - - - 0.000000000000000000000000000000008776 132.0
HKD2_k127_7912479_5 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000003986 100.0
HKD2_k127_7912479_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000005286 76.0
HKD2_k127_7912479_7 PFAM Transposase IS200 like K07491 - - 0.00000007062 60.0
HKD2_k127_7912479_8 Transposase - - - 0.0000003248 60.0
HKD2_k127_7912479_9 Heavy-metal-associated domain K07213 - - 0.0004385 53.0
HKD2_k127_7965636_0 4Fe-4S dicluster domain - - - 6.439e-262 842.0
HKD2_k127_7965636_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 489.0
HKD2_k127_7965636_10 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000003075 127.0
HKD2_k127_7965636_11 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000001477 113.0
HKD2_k127_7965636_13 peptidyl-tyrosine sulfation - - - 0.000000000004157 79.0
HKD2_k127_7965636_14 transferase activity, transferring glycosyl groups - - - 0.0001086 51.0
HKD2_k127_7965636_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 456.0
HKD2_k127_7965636_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 402.0
HKD2_k127_7965636_4 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
HKD2_k127_7965636_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 321.0
HKD2_k127_7965636_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 293.0
HKD2_k127_7965636_7 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000002665 193.0
HKD2_k127_7965636_8 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000000000000000000000000000000345 179.0
HKD2_k127_7965636_9 - - - - 0.000000000000000000000000000000000000004636 149.0
HKD2_k127_7990200_0 Glycogen debranching enzyme - - - 0.0 1462.0
HKD2_k127_7990200_1 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 5.055e-255 812.0
HKD2_k127_7990200_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000003396 179.0
HKD2_k127_7990200_3 RNA-binding - - - 0.000000000000000000000000002688 115.0
HKD2_k127_7990200_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000009751 93.0
HKD2_k127_7990200_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000002801 94.0
HKD2_k127_8033690_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 4.719e-246 768.0
HKD2_k127_8033690_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 612.0
HKD2_k127_8033690_10 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000006727 179.0
HKD2_k127_8033690_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000006352 184.0
HKD2_k127_8033690_12 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000002525 184.0
HKD2_k127_8033690_13 PhoQ Sensor - - - 0.0000000000000000000000000000000000000001119 165.0
HKD2_k127_8033690_14 - - - - 0.0000000000000000000000000000009957 124.0
HKD2_k127_8033690_15 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000109 113.0
HKD2_k127_8033690_16 Methyltransferase domain - - - 0.0000000000000000000000005834 118.0
HKD2_k127_8033690_17 - - - - 0.0000000000000001533 84.0
HKD2_k127_8033690_18 secretion pathway protein K02456 - - 0.000000000002115 74.0
HKD2_k127_8033690_19 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000009207 74.0
HKD2_k127_8033690_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 516.0
HKD2_k127_8033690_20 energy transducer activity K03832 - - 0.00002848 49.0
HKD2_k127_8033690_21 6-phosphogluconolactonase activity - - - 0.0004406 51.0
HKD2_k127_8033690_3 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 514.0
HKD2_k127_8033690_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 472.0
HKD2_k127_8033690_5 inositol 2-dehydrogenase activity K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 411.0
HKD2_k127_8033690_6 PFAM Peptidase family M20 M25 M40 K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 391.0
HKD2_k127_8033690_7 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 334.0
HKD2_k127_8033690_8 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000004798 243.0
HKD2_k127_8033690_9 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000009151 243.0
HKD2_k127_817628_0 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 418.0
HKD2_k127_817628_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 389.0
HKD2_k127_817628_10 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000002047 246.0
HKD2_k127_817628_11 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000001353 228.0
HKD2_k127_817628_12 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000001453 218.0
HKD2_k127_817628_13 Belongs to the MraZ family K03925 - - 0.000000000000000000000004999 108.0
HKD2_k127_817628_14 TamB, inner membrane protein subunit of TAM complex - - - 0.000000001031 73.0
HKD2_k127_817628_15 - - - - 0.00000004309 64.0
HKD2_k127_817628_16 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0004981 44.0
HKD2_k127_817628_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 385.0
HKD2_k127_817628_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 358.0
HKD2_k127_817628_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 310.0
HKD2_k127_817628_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 293.0
HKD2_k127_817628_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 295.0
HKD2_k127_817628_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001491 263.0
HKD2_k127_817628_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001335 270.0
HKD2_k127_817628_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000005526 263.0
HKD2_k127_8235668_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.324e-217 700.0
HKD2_k127_8235668_1 Protein conserved in bacteria K07011 - - 0.000000000000000000000000000000000000000000000000003759 190.0
HKD2_k127_8235668_2 - - - - 0.00000000000000000004505 91.0
HKD2_k127_8235668_3 - - - - 0.00000001028 67.0
HKD2_k127_8253908_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.607e-283 903.0
HKD2_k127_8253908_1 Histidine kinase K07646 - 2.7.13.3 2.519e-257 822.0
HKD2_k127_8253908_10 rhomboid-domain-containing protein K09650 - 3.4.21.105 0.0000000000000000000001668 106.0
HKD2_k127_8253908_11 Transport and Golgi organisation 2 - - - 0.000000000008509 75.0
HKD2_k127_8253908_12 - - - - 0.0000000001115 72.0
HKD2_k127_8253908_13 oxidoreductase activity - - - 0.0000000001631 74.0
HKD2_k127_8253908_14 Transport of potassium into the cell K03549 - - 0.000000002415 60.0
HKD2_k127_8253908_15 Protein of unknown function (DUF2490) - - - 0.00000004229 63.0
HKD2_k127_8253908_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 9.252e-224 709.0
HKD2_k127_8253908_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 621.0
HKD2_k127_8253908_4 Peptidase m28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 553.0
HKD2_k127_8253908_5 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 414.0
HKD2_k127_8253908_6 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 313.0
HKD2_k127_8253908_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
HKD2_k127_8253908_8 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003145 234.0
HKD2_k127_8253908_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000002608 222.0
HKD2_k127_829496_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
HKD2_k127_829496_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001795 280.0
HKD2_k127_829496_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000002865 187.0
HKD2_k127_829496_3 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000007674 141.0
HKD2_k127_829496_4 of the beta-lactamase K00784 - 3.1.26.11 0.000000000000000000000000000000016 143.0
HKD2_k127_8302606_0 Peptidase family M28 - - - 1.611e-296 949.0
HKD2_k127_8302606_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 505.0
HKD2_k127_8302606_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000007102 254.0
HKD2_k127_8302606_11 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000001723 194.0
HKD2_k127_8302606_12 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000003324 186.0
HKD2_k127_8302606_13 iron-sulfur cluster assembly K07400,K13628 - - 0.0000000000000000000000000000000000000000000408 168.0
HKD2_k127_8302606_14 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000000000000000000000005112 152.0
HKD2_k127_8302606_15 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000002101 160.0
HKD2_k127_8302606_16 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000005053 149.0
HKD2_k127_8302606_17 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000000008406 123.0
HKD2_k127_8302606_18 Calcineurin-like phosphoesterase - - - 0.0000000000000000000004522 106.0
HKD2_k127_8302606_2 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 413.0
HKD2_k127_8302606_20 - - - - 0.00000001946 57.0
HKD2_k127_8302606_21 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000002234 52.0
HKD2_k127_8302606_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 411.0
HKD2_k127_8302606_4 PFAM transferase hexapeptide repeat containing protein K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 350.0
HKD2_k127_8302606_5 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 328.0
HKD2_k127_8302606_6 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 323.0
HKD2_k127_8302606_7 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 316.0
HKD2_k127_8302606_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007531 297.0
HKD2_k127_8302606_9 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000936 264.0
HKD2_k127_8335059_0 5' nucleotidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 584.0
HKD2_k127_8335059_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 498.0
HKD2_k127_8335059_10 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003352 266.0
HKD2_k127_8335059_11 Outer membrane protein beta-barrel family K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000001569 250.0
HKD2_k127_8335059_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000777 233.0
HKD2_k127_8335059_13 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000001357 205.0
HKD2_k127_8335059_14 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000004605 199.0
HKD2_k127_8335059_15 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000001433 121.0
HKD2_k127_8335059_16 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000003838 128.0
HKD2_k127_8335059_17 methylated DNA-protein cysteine methyltransferase K07443 - - 0.00000000000000000003076 96.0
HKD2_k127_8335059_18 Stress-responsive transcriptional regulator - - - 0.000000000000000001403 89.0
HKD2_k127_8335059_19 protein-disulfide reductase activity - - - 0.00000000000002521 79.0
HKD2_k127_8335059_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 495.0
HKD2_k127_8335059_20 Membrane - - - 0.00000000001573 75.0
HKD2_k127_8335059_3 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 432.0
HKD2_k127_8335059_4 ABC transporter K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 419.0
HKD2_k127_8335059_5 ABC transporter transmembrane region K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 398.0
HKD2_k127_8335059_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 360.0
HKD2_k127_8335059_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
HKD2_k127_8335059_8 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 305.0
HKD2_k127_8335059_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 285.0
HKD2_k127_8363589_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 423.0
HKD2_k127_8493098_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.632e-265 838.0
HKD2_k127_8493098_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.707e-253 808.0
HKD2_k127_8493098_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
HKD2_k127_8493098_11 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000004278 227.0
HKD2_k127_8493098_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000002228 223.0
HKD2_k127_8493098_13 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000004079 185.0
HKD2_k127_8493098_14 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000004961 173.0
HKD2_k127_8493098_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000001441 149.0
HKD2_k127_8493098_16 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000003584 144.0
HKD2_k127_8493098_17 acetyltransferase - - - 0.000000000000000000000000000000129 132.0
HKD2_k127_8493098_18 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000008576 123.0
HKD2_k127_8493098_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000002068 113.0
HKD2_k127_8493098_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.026e-232 726.0
HKD2_k127_8493098_20 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000001106 113.0
HKD2_k127_8493098_21 Polymer-forming cytoskeletal - - - 0.0000000000000000000416 97.0
HKD2_k127_8493098_22 R3H domain protein K06346 - - 0.0000000000000000148 96.0
HKD2_k127_8493098_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000001214 84.0
HKD2_k127_8493098_24 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000002993 67.0
HKD2_k127_8493098_25 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000306 72.0
HKD2_k127_8493098_26 CAAX protease self-immunity K07052 - - 0.00000002659 62.0
HKD2_k127_8493098_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00004449 52.0
HKD2_k127_8493098_29 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0006514 49.0
HKD2_k127_8493098_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 6.428e-225 707.0
HKD2_k127_8493098_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 540.0
HKD2_k127_8493098_5 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 403.0
HKD2_k127_8493098_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 375.0
HKD2_k127_8493098_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 297.0
HKD2_k127_8493098_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002151 293.0
HKD2_k127_8493098_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001376 287.0
HKD2_k127_8493777_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1033.0
HKD2_k127_8493777_1 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 452.0
HKD2_k127_8500686_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 373.0
HKD2_k127_8500686_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 348.0
HKD2_k127_8500686_2 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000003404 190.0
HKD2_k127_8713131_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 490.0
HKD2_k127_8713131_1 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 300.0
HKD2_k127_8713131_2 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 304.0
HKD2_k127_8713131_3 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000005508 207.0
HKD2_k127_8713131_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000123 203.0
HKD2_k127_893163_0 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 459.0
HKD2_k127_893163_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 295.0
HKD2_k127_893163_10 peptidylprolyl isomerase K01802 - 5.2.1.8 0.000128 55.0
HKD2_k127_893163_2 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000517 292.0
HKD2_k127_893163_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001415 243.0
HKD2_k127_893163_4 Kelch motif - - - 0.000000000000000000000000000000000000000000001669 189.0
HKD2_k127_893163_5 F-box LRR-repeat protein - - - 0.000000000000000000000000000000004123 143.0
HKD2_k127_893163_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000005943 91.0
HKD2_k127_893163_7 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000009538 78.0
HKD2_k127_893163_8 Periplasmic or secreted lipoprotein - - - 0.0000111 57.0
HKD2_k127_893163_9 COG0457 FOG TPR repeat - - - 0.00001508 51.0
HKD2_k127_8959993_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 1.408e-224 707.0
HKD2_k127_8959993_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 567.0
HKD2_k127_8959993_10 spore germination K03605 - - 0.000000000000000000000001816 115.0
HKD2_k127_8959993_11 FAD-NAD(P)-binding K01069 - 3.1.2.6 0.0000000000000000000003604 103.0
HKD2_k127_8959993_12 - - - - 0.000000009342 63.0
HKD2_k127_8959993_13 - - - - 0.0000001804 60.0
HKD2_k127_8959993_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 464.0
HKD2_k127_8959993_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 383.0
HKD2_k127_8959993_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 365.0
HKD2_k127_8959993_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 352.0
HKD2_k127_8959993_6 FAD-NAD(P)-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001279 281.0
HKD2_k127_8959993_7 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004601 264.0
HKD2_k127_8959993_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000005268 187.0
HKD2_k127_8959993_9 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000989 118.0
HKD2_k127_8987998_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 544.0
HKD2_k127_8987998_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 424.0
HKD2_k127_8987998_10 lysyltransferase activity K07027 - - 0.000000000000206 84.0
HKD2_k127_8987998_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000001456 54.0
HKD2_k127_8987998_2 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 402.0
HKD2_k127_8987998_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 309.0
HKD2_k127_8987998_4 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 313.0
HKD2_k127_8987998_5 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 302.0
HKD2_k127_8987998_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003748 267.0
HKD2_k127_8987998_7 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001018 263.0
HKD2_k127_8987998_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000005738 134.0
HKD2_k127_8987998_9 - - - - 0.00000000000000000000000001782 121.0
HKD2_k127_8995876_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 430.0
HKD2_k127_8995876_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 399.0
HKD2_k127_8995876_10 Lysyl oxidase - - - 0.0000007026 64.0
HKD2_k127_8995876_2 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 419.0
HKD2_k127_8995876_3 TIGRFAM phosphate ABC transporter, inner membrane subunit PstC K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 374.0
HKD2_k127_8995876_4 PFAM Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 370.0
HKD2_k127_8995876_5 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 358.0
HKD2_k127_8995876_6 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 313.0
HKD2_k127_8995876_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000001679 228.0
HKD2_k127_8995876_8 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000005169 163.0
HKD2_k127_8995876_9 cellulose binding - - - 0.000000000102 73.0
HKD2_k127_9026766_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.491e-218 696.0
HKD2_k127_9026766_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 617.0
HKD2_k127_9026766_10 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 310.0
HKD2_k127_9026766_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000559 278.0
HKD2_k127_9026766_12 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003723 291.0
HKD2_k127_9026766_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
HKD2_k127_9026766_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000009422 187.0
HKD2_k127_9026766_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000009209 179.0
HKD2_k127_9026766_16 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000005668 162.0
HKD2_k127_9026766_17 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000001275 155.0
HKD2_k127_9026766_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000007489 154.0
HKD2_k127_9026766_19 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000001595 148.0
HKD2_k127_9026766_2 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 429.0
HKD2_k127_9026766_20 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001973 141.0
HKD2_k127_9026766_21 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000000000000009444 143.0
HKD2_k127_9026766_22 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions K01519 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000006531 142.0
HKD2_k127_9026766_23 positive regulation of growth rate - - - 0.000000000000000000000000000000005315 142.0
HKD2_k127_9026766_24 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000001153 136.0
HKD2_k127_9026766_25 Tetratricopeptide repeat K05807 - - 0.000000000000000000009482 105.0
HKD2_k127_9026766_26 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001124 81.0
HKD2_k127_9026766_27 PFAM PASTA domain - - - 0.000000000001867 81.0
HKD2_k127_9026766_28 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000001128 61.0
HKD2_k127_9026766_29 receptor - - - 0.0000003761 55.0
HKD2_k127_9026766_3 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 407.0
HKD2_k127_9026766_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 368.0
HKD2_k127_9026766_5 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 364.0
HKD2_k127_9026766_6 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 332.0
HKD2_k127_9026766_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
HKD2_k127_9026766_8 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 323.0
HKD2_k127_9026766_9 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 314.0
HKD2_k127_9035917_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1403.0
HKD2_k127_9035917_1 Insulinase (Peptidase family M16) - - - 3.648e-270 863.0
HKD2_k127_9035917_10 - - - - 0.000003338 58.0
HKD2_k127_9035917_11 Glucose / Sorbosone dehydrogenase - - - 0.00007644 55.0
HKD2_k127_9035917_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 480.0
HKD2_k127_9035917_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 398.0
HKD2_k127_9035917_4 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 398.0
HKD2_k127_9035917_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000003299 153.0
HKD2_k127_9035917_6 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000005762 134.0
HKD2_k127_9035917_7 Flagellar filament outer layer protein Flaa - - - 0.00000000000000000000000069 121.0
HKD2_k127_9035917_9 Regulatory protein, FmdB family - - - 0.00000008406 64.0
HKD2_k127_9071915_0 TIGRFAM leucyl-tRNA synthetase, eubacterial and mitochondrial family - - - 0.0 1156.0
HKD2_k127_9071915_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.991e-294 944.0
HKD2_k127_9071915_10 - - - - 0.0000000000000000000000000000000000011 145.0
HKD2_k127_9071915_11 Heavy-metal resistance - - - 0.000000000001874 74.0
HKD2_k127_9071915_12 - - - - 0.00000253 56.0
HKD2_k127_9071915_13 - - - - 0.000003208 59.0
HKD2_k127_9071915_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 520.0
HKD2_k127_9071915_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 487.0
HKD2_k127_9071915_4 Transcriptional regulatory protein, C terminal K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 285.0
HKD2_k127_9071915_5 PhoQ Sensor K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008611 274.0
HKD2_k127_9071915_6 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
HKD2_k127_9071915_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000001689 256.0
HKD2_k127_9071915_8 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000008203 186.0
HKD2_k127_9071915_9 NikR C terminal nickel binding domain - - - 0.000000000000000000000000000000000000000000002954 168.0
HKD2_k127_9073734_0 aconitate hydratase activity K01681 - 4.2.1.3 2.395e-309 971.0
HKD2_k127_9073734_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 474.0
HKD2_k127_9073734_10 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000007406 178.0
HKD2_k127_9073734_11 Sulfatase - - - 0.0000000000000000000000000000000000000000000004275 191.0
HKD2_k127_9073734_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000003133 171.0
HKD2_k127_9073734_13 ASPIC and UnbV - - - 0.0000000000000000000000000000000005194 151.0
HKD2_k127_9073734_14 Belongs to the Fur family K09825 - - 0.00000000000000000000000000002564 123.0
HKD2_k127_9073734_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000001013 121.0
HKD2_k127_9073734_16 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001175 119.0
HKD2_k127_9073734_17 Domain of unknown function (DUF4920) - - - 0.000000000000000006821 92.0
HKD2_k127_9073734_18 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000001681 73.0
HKD2_k127_9073734_19 - - - - 0.000004944 56.0
HKD2_k127_9073734_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005644 282.0
HKD2_k127_9073734_20 Carboxypeptidase regulatory-like domain - - - 0.0003513 52.0
HKD2_k127_9073734_21 Anti-sigma-K factor rskA - - - 0.0009232 49.0
HKD2_k127_9073734_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001445 271.0
HKD2_k127_9073734_4 glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000008289 237.0
HKD2_k127_9073734_5 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000003716 209.0
HKD2_k127_9073734_6 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000003258 217.0
HKD2_k127_9073734_7 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000391 214.0
HKD2_k127_9073734_8 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000009569 189.0
HKD2_k127_9073734_9 Glycosyltransferase like family 2 K12992 - - 0.000000000000000000000000000000000000000000000009877 197.0
HKD2_k127_9148694_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 461.0
HKD2_k127_9148694_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 430.0
HKD2_k127_9148694_10 oxidase subunit K08738 - - 0.00000000000000000000000000000000000000000001002 179.0
HKD2_k127_9148694_11 bacteriocin transport K03561 - - 0.00000000000000000000000000000000000000002962 160.0
HKD2_k127_9148694_12 transcriptional regulator - - - 0.00000000000000000000000000000001209 137.0
HKD2_k127_9148694_13 Belongs to the Fur family K03711 - - 0.000000000000000000000000000002703 125.0
HKD2_k127_9148694_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000001245 125.0
HKD2_k127_9148694_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.000000000000000000000002536 118.0
HKD2_k127_9148694_16 Belongs to the RimK family K05844 - - 0.000000000000000000000005215 106.0
HKD2_k127_9148694_17 PFAM Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000005915 114.0
HKD2_k127_9148694_18 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000004665 87.0
HKD2_k127_9148694_19 TIGRFAM TonB K03832 - - 0.0000000000001978 80.0
HKD2_k127_9148694_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
HKD2_k127_9148694_20 protein secretion K03116 - - 0.0000000003452 63.0
HKD2_k127_9148694_21 - - - - 0.00006021 50.0
HKD2_k127_9148694_22 Biopolymer transporter ExbD K03559 - - 0.0000868 53.0
HKD2_k127_9148694_25 cell division K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.0005611 51.0
HKD2_k127_9148694_3 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 317.0
HKD2_k127_9148694_4 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 325.0
HKD2_k127_9148694_5 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 320.0
HKD2_k127_9148694_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009579 282.0
HKD2_k127_9148694_7 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.00000000000000000000000000000000000000000000000000000000922 219.0
HKD2_k127_9148694_8 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000002068 207.0
HKD2_k127_9148694_9 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000005996 184.0
HKD2_k127_9198470_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 541.0
HKD2_k127_9198470_1 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 363.0
HKD2_k127_9198470_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000008571 139.0
HKD2_k127_9198470_11 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000000003656 120.0
HKD2_k127_9198470_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000001364 109.0
HKD2_k127_9198470_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000000796 81.0
HKD2_k127_9198470_14 COG1960 Acyl-CoA dehydrogenases K00252 - 1.3.8.6 0.0000000004657 60.0
HKD2_k127_9198470_15 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000001811 53.0
HKD2_k127_9198470_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 362.0
HKD2_k127_9198470_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000007605 247.0
HKD2_k127_9198470_4 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000001835 246.0
HKD2_k127_9198470_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001341 235.0
HKD2_k127_9198470_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000003268 180.0
HKD2_k127_9198470_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000004438 169.0
HKD2_k127_9198470_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.000000000000000000000000000000000000194 160.0
HKD2_k127_9198470_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.0000000000000000000000000000000000003794 158.0
HKD2_k127_9226052_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 432.0
HKD2_k127_9226052_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 400.0
HKD2_k127_9226052_10 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000001357 164.0
HKD2_k127_9226052_11 Putative adhesin - - - 0.000000000000000000000000000000000001304 149.0
HKD2_k127_9226052_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000003315 127.0
HKD2_k127_9226052_13 Cytidylate kinase-like family K00945 - 2.7.4.25 0.0000000000000000000000000007943 123.0
HKD2_k127_9226052_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 373.0
HKD2_k127_9226052_3 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 378.0
HKD2_k127_9226052_4 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 300.0
HKD2_k127_9226052_5 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002767 268.0
HKD2_k127_9226052_6 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
HKD2_k127_9226052_7 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000007408 168.0
HKD2_k127_9226052_8 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000001547 166.0
HKD2_k127_9226052_9 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000002438 175.0
HKD2_k127_931511_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 598.0
HKD2_k127_931511_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 522.0
HKD2_k127_931511_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 410.0
HKD2_k127_9340036_0 elongation factor G K02355 - - 7.393e-215 687.0
HKD2_k127_9340036_1 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 496.0
HKD2_k127_9340036_10 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000006494 140.0
HKD2_k127_9340036_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000006941 136.0
HKD2_k127_9340036_12 Outer membrane lipoprotein - - - 0.0000000000000000000000007932 115.0
HKD2_k127_9340036_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000004152 115.0
HKD2_k127_9340036_14 SpoU rRNA Methylase family K00556 - 2.1.1.34 0.000000000000000001201 94.0
HKD2_k127_9340036_15 Protein of unknown function, DUF255 - - - 0.000000000000000001359 94.0
HKD2_k127_9340036_16 Ribosomal protein S20 K02968 - - 0.00000000001836 68.0
HKD2_k127_9340036_18 chitin binding K01183 - 3.2.1.14 0.000006976 50.0
HKD2_k127_9340036_19 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000114 47.0
HKD2_k127_9340036_2 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 322.0
HKD2_k127_9340036_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 306.0
HKD2_k127_9340036_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001099 218.0
HKD2_k127_9340036_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000002211 196.0
HKD2_k127_9340036_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000004308 164.0
HKD2_k127_9340036_7 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000001635 163.0
HKD2_k127_9340036_8 domain, Protein - - - 0.00000000000000000000000000000000003202 155.0
HKD2_k127_9340036_9 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000003337 141.0
HKD2_k127_9376058_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000001485 245.0
HKD2_k127_9376058_1 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000002103 246.0
HKD2_k127_9376058_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000007997 173.0
HKD2_k127_9469590_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 464.0
HKD2_k127_9469590_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 326.0
HKD2_k127_9469590_2 - - - - 0.00000000000000000000000000000009055 134.0
HKD2_k127_9514844_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.496e-230 728.0
HKD2_k127_9514844_1 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 6.84e-196 622.0
HKD2_k127_9514844_10 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 342.0
HKD2_k127_9514844_11 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 300.0
HKD2_k127_9514844_12 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001193 273.0
HKD2_k127_9514844_13 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002257 265.0
HKD2_k127_9514844_14 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000937 207.0
HKD2_k127_9514844_15 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000007425 203.0
HKD2_k127_9514844_16 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000002064 184.0
HKD2_k127_9514844_17 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000001799 193.0
HKD2_k127_9514844_18 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000001503 137.0
HKD2_k127_9514844_19 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000005166 130.0
HKD2_k127_9514844_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 534.0
HKD2_k127_9514844_20 - - - - 0.000000000000000000000000000001876 134.0
HKD2_k127_9514844_21 - - - - 0.000000000000000000000000000004061 138.0
HKD2_k127_9514844_22 PFAM Membrane protein of K08972 - - 0.000000000000000000000004318 109.0
HKD2_k127_9514844_23 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000001069 73.0
HKD2_k127_9514844_24 FAD dependent oxidoreductase - - - 0.0000003013 63.0
HKD2_k127_9514844_25 Glycosyl transferase, family 2 - - - 0.0005735 53.0
HKD2_k127_9514844_3 Oligopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 536.0
HKD2_k127_9514844_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 489.0
HKD2_k127_9514844_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 439.0
HKD2_k127_9514844_6 COG1294 Cytochrome bd-type quinol oxidase subunit 2 K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 434.0
HKD2_k127_9514844_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 415.0
HKD2_k127_9514844_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
HKD2_k127_9514844_9 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 335.0
HKD2_k127_9609859_0 Sulfate permease family K03321 - - 1.543e-233 736.0
HKD2_k127_9609859_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.084e-210 667.0
HKD2_k127_9609859_10 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 362.0
HKD2_k127_9609859_11 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 308.0
HKD2_k127_9609859_12 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001729 295.0
HKD2_k127_9609859_13 amine dehydrogenase activity K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001002 296.0
HKD2_k127_9609859_14 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004205 287.0
HKD2_k127_9609859_15 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000008399 252.0
HKD2_k127_9609859_16 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008188 231.0
HKD2_k127_9609859_17 arylsulfatase activity K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000001754 238.0
HKD2_k127_9609859_18 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001505 223.0
HKD2_k127_9609859_19 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000001458 217.0
HKD2_k127_9609859_2 oligopeptide transport K03305 - - 2.361e-209 662.0
HKD2_k127_9609859_20 PFAM Low molecular weight phosphotyrosine protein phosphatase K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HKD2_k127_9609859_21 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000007209 225.0
HKD2_k127_9609859_22 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000121 198.0
HKD2_k127_9609859_23 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.0000000000000000000000000000000000000000000000624 189.0
HKD2_k127_9609859_24 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000002474 188.0
HKD2_k127_9609859_25 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000005516 184.0
HKD2_k127_9609859_26 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000001789 169.0
HKD2_k127_9609859_27 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000001866 168.0
HKD2_k127_9609859_28 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000761 147.0
HKD2_k127_9609859_29 SMART regulatory protein ArsR - - - 0.0000000000000000000000000000000000009906 143.0
HKD2_k127_9609859_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 582.0
HKD2_k127_9609859_30 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000001229 143.0
HKD2_k127_9609859_31 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000003599 143.0
HKD2_k127_9609859_32 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000007424 137.0
HKD2_k127_9609859_33 Conserved repeat domain - - - 0.0000000000000000000000000006072 132.0
HKD2_k127_9609859_34 - - - - 0.000000000000000000000000004393 115.0
HKD2_k127_9609859_35 Transcriptional regulator K03892,K21903 - - 0.0000000000000000000007952 100.0
HKD2_k127_9609859_36 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000000001158 98.0
HKD2_k127_9609859_38 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000006836 99.0
HKD2_k127_9609859_39 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000007147 93.0
HKD2_k127_9609859_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 548.0
HKD2_k127_9609859_40 antisigma factor binding - - - 0.0000000000000001294 85.0
HKD2_k127_9609859_41 PFAM ATP-binding region, ATPase domain protein K04757 - 2.7.11.1 0.000000000005559 71.0
HKD2_k127_9609859_42 - - - - 0.0000000003647 70.0
HKD2_k127_9609859_43 Domain of unknown function (DUF4388) - - - 0.000000001733 70.0
HKD2_k127_9609859_44 aminotransferase class I and II - - - 0.000000003794 69.0
HKD2_k127_9609859_46 Endonuclease Exonuclease Phosphatase - - - 0.000001774 59.0
HKD2_k127_9609859_47 YacP-like NYN domain K06962 - - 0.00001236 54.0
HKD2_k127_9609859_48 protein conserved in bacteria - - - 0.0002042 51.0
HKD2_k127_9609859_5 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 492.0
HKD2_k127_9609859_6 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 486.0
HKD2_k127_9609859_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
HKD2_k127_9609859_8 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 418.0
HKD2_k127_9609859_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 417.0
HKD2_k127_9646488_0 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 3.412e-246 769.0
HKD2_k127_9646488_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 604.0
HKD2_k127_9646488_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 421.0
HKD2_k127_9646488_3 HpcH/HpaI aldolase/citrate lyase family K01644,K01646,K18292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 359.0
HKD2_k127_9646488_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008636 295.0
HKD2_k127_9646488_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000003066 115.0
HKD2_k127_9646488_6 Binds the 23S rRNA K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004597 105.0
HKD2_k127_9646488_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000004932 72.0
HKD2_k127_9786745_0 - - - - 3.418e-218 709.0
HKD2_k127_9786745_1 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 410.0
HKD2_k127_9786745_10 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000002452 216.0
HKD2_k127_9786745_11 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000003488 192.0
HKD2_k127_9786745_12 enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000234 195.0
HKD2_k127_9786745_13 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000001766 159.0
HKD2_k127_9786745_14 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000006901 128.0
HKD2_k127_9786745_15 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000001068 136.0
HKD2_k127_9786745_16 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000004493 124.0
HKD2_k127_9786745_17 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000008121 113.0
HKD2_k127_9786745_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000001124 108.0
HKD2_k127_9786745_19 glycosyl transferase family 2 K07011 - - 0.0000000000001348 83.0
HKD2_k127_9786745_2 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 391.0
HKD2_k127_9786745_20 - - - - 0.00000002206 69.0
HKD2_k127_9786745_3 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 320.0
HKD2_k127_9786745_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 288.0
HKD2_k127_9786745_5 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001029 283.0
HKD2_k127_9786745_6 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HKD2_k127_9786745_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000139 243.0
HKD2_k127_9786745_8 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000005326 217.0
HKD2_k127_9786745_9 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000001411 214.0
HKD2_k127_9791305_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.904e-252 791.0
HKD2_k127_9791305_1 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 608.0
HKD2_k127_9791305_10 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000003699 108.0
HKD2_k127_9791305_11 membrane transporter protein K07090 - - 0.000000000000000008345 95.0
HKD2_k127_9791305_12 Glycosyl transferases group 1 - - - 0.0000000000006153 75.0
HKD2_k127_9791305_13 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000384 72.0
HKD2_k127_9791305_14 Acetyltransferase (GNAT) domain - - - 0.00000001255 68.0
HKD2_k127_9791305_2 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 439.0
HKD2_k127_9791305_3 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 338.0
HKD2_k127_9791305_4 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 339.0
HKD2_k127_9791305_5 BFD domain protein 2Fe-2S -binding domain protein K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005772 310.0
HKD2_k127_9791305_6 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003147 300.0
HKD2_k127_9791305_7 - - - - 0.0000000000000000000000000000000000000000000000003348 195.0
HKD2_k127_9791305_8 - - - - 0.00000000000000000000000000000002822 138.0
HKD2_k127_9791305_9 Bacterial membrane protein YfhO - - - 0.000000000000000000000000155 124.0
HKD2_k127_9832472_0 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.709e-286 910.0
HKD2_k127_9832472_1 cellulose binding - - - 1.633e-234 745.0
HKD2_k127_9832472_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000411 126.0
HKD2_k127_9832472_12 membrane K12340 - - 0.0000000000003097 83.0
HKD2_k127_9832472_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 8.296e-223 727.0
HKD2_k127_9832472_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 383.0
HKD2_k127_9832472_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 323.0
HKD2_k127_9832472_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008876 281.0
HKD2_k127_9832472_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008138 282.0
HKD2_k127_9832472_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000001688 225.0
HKD2_k127_9832472_8 Belongs to the peptidase S8 family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000003787 220.0
HKD2_k127_9832472_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000005583 136.0