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Overview

ID MAG01820
Name HKD2_bin.8
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family Anaerolineaceae
Genus DAIOEK01
Species
Assembly information
Completeness (%) 82.27
Contamination (%) 1.17
GC content (%) 48.0
N50 (bp) 9,256
Genome size (bp) 2,443,179

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2286

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_1008683_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1397.0
HKD2_k127_1008683_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 585.0
HKD2_k127_1008683_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
HKD2_k127_1008683_3 Protein of unknown function (DUF952) - - - 0.000000000000000004754 88.0
HKD2_k127_1008683_4 Uncharacterized membrane protein (DUF2298) - - - 0.0000000008663 64.0
HKD2_k127_10130352_0 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 483.0
HKD2_k127_10130352_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 466.0
HKD2_k127_10130352_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 361.0
HKD2_k127_10130352_3 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003313 239.0
HKD2_k127_10130352_5 PFAM glycoside hydrolase, family 18 - - - 0.0000000000000000000000000000000009118 146.0
HKD2_k127_1030574_0 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 582.0
HKD2_k127_1030574_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 507.0
HKD2_k127_1030574_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 334.0
HKD2_k127_1030574_3 - - - - 0.00000002635 58.0
HKD2_k127_1046969_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.977e-288 895.0
HKD2_k127_1046969_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 567.0
HKD2_k127_1046969_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000003273 177.0
HKD2_k127_1046969_11 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000007349 160.0
HKD2_k127_1046969_12 - - - - 0.00000000000000000000000000000000000004891 150.0
HKD2_k127_1046969_13 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000000003526 148.0
HKD2_k127_1046969_14 transcriptional activator domain - - - 0.0000000000000000000001273 109.0
HKD2_k127_1046969_2 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 497.0
HKD2_k127_1046969_3 Monogalactosyldiacylglycerol synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 339.0
HKD2_k127_1046969_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
HKD2_k127_1046969_5 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007767 272.0
HKD2_k127_1046969_6 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 246.0
HKD2_k127_1046969_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000002817 242.0
HKD2_k127_1046969_8 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000001795 192.0
HKD2_k127_1046969_9 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000000002126 183.0
HKD2_k127_1062574_0 PFAM peptidase S58, DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 371.0
HKD2_k127_1062574_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 310.0
HKD2_k127_1062574_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 289.0
HKD2_k127_1062574_3 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
HKD2_k127_1062574_4 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000686 210.0
HKD2_k127_1062574_5 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000001478 199.0
HKD2_k127_1062574_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000003274 105.0
HKD2_k127_1062574_7 acetyltransferase - - - 0.00001286 48.0
HKD2_k127_1118675_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 432.0
HKD2_k127_1118675_1 WD domain, G-beta repeat - - - 0.000002601 59.0
HKD2_k127_1128496_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.64e-276 859.0
HKD2_k127_1128496_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 510.0
HKD2_k127_1128496_2 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 309.0
HKD2_k127_1128496_3 DNA-binding transcription factor activity K03710 - - 0.000000000000000000000000000000000000004139 155.0
HKD2_k127_1128496_4 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000001373 142.0
HKD2_k127_1128496_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000001526 136.0
HKD2_k127_1128496_6 DNA-binding transcription factor activity - - - 0.00000000000000000005072 95.0
HKD2_k127_114071_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1196.0
HKD2_k127_114071_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 326.0
HKD2_k127_114071_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002806 235.0
HKD2_k127_114071_3 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000004895 211.0
HKD2_k127_1150257_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1255.0
HKD2_k127_1150257_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000001881 186.0
HKD2_k127_1150257_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000005748 194.0
HKD2_k127_1150257_3 Histidine phosphatase superfamily (branch 1) K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000002618 170.0
HKD2_k127_1150257_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000001653 61.0
HKD2_k127_1150257_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00002314 47.0
HKD2_k127_1200910_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.543e-246 766.0
HKD2_k127_1200910_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.474e-224 710.0
HKD2_k127_1200910_10 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000007341 103.0
HKD2_k127_1200910_11 metal-dependent phosphohydrolase, HD sub domain - - - 0.000002438 49.0
HKD2_k127_1200910_2 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 591.0
HKD2_k127_1200910_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 579.0
HKD2_k127_1200910_4 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 470.0
HKD2_k127_1200910_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 462.0
HKD2_k127_1200910_6 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 459.0
HKD2_k127_1200910_7 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 441.0
HKD2_k127_1200910_8 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000009081 128.0
HKD2_k127_1200910_9 - - - - 0.0000000000000000000000001747 112.0
HKD2_k127_1303194_0 Bacterial extracellular solute-binding protein K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 464.0
HKD2_k127_1303194_1 Binding-protein-dependent transport system inner membrane component K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 448.0
HKD2_k127_1303194_2 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 428.0
HKD2_k127_1303194_3 TOBE domain K02062,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 341.0
HKD2_k127_1303194_4 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000002674 222.0
HKD2_k127_1303194_5 Hemerythrin HHE cation binding - - - 0.000000000000000000000000000000000000009012 153.0
HKD2_k127_1303194_6 thiamine K00949 - 2.7.6.2 0.00000000000000000000000000000000001559 143.0
HKD2_k127_1303194_7 Protein of unknown function (DUF402) K07586 - - 0.00000000000000000000000000008669 121.0
HKD2_k127_1303194_8 - - - - 0.000000001312 64.0
HKD2_k127_1316945_0 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 389.0
HKD2_k127_1316945_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 336.0
HKD2_k127_1316945_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000151 263.0
HKD2_k127_1316945_3 Integral membrane protein (intg_mem_TP0381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HKD2_k127_1316945_4 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000001374 207.0
HKD2_k127_1316945_5 WLM domain K07043 - - 0.00000000000000000000000000000000000000000008786 168.0
HKD2_k127_1316945_6 phosphoesterase, PA-phosphatase related - - - 0.00000000000005145 80.0
HKD2_k127_1382438_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.048e-300 930.0
HKD2_k127_1382438_1 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 394.0
HKD2_k127_1382438_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000004213 206.0
HKD2_k127_1382438_3 protein conserved in bacteria - - - 0.0000000000000000000001071 97.0
HKD2_k127_1383977_0 Bacterial pre-peptidase C-terminal domain - - - 1.57e-210 702.0
HKD2_k127_1383977_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 2.639e-197 624.0
HKD2_k127_1383977_10 RNA-DNA hybrid ribonuclease activity K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000000000000000000244 158.0
HKD2_k127_1383977_11 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000002367 143.0
HKD2_k127_1383977_12 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000001001 137.0
HKD2_k127_1383977_13 EamA-like transporter family - - - 0.0000000000000000000000000000003233 134.0
HKD2_k127_1383977_14 transcription factor binding - - - 0.0000000000000000000000000006985 116.0
HKD2_k127_1383977_15 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000001757 118.0
HKD2_k127_1383977_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 520.0
HKD2_k127_1383977_3 PFAM IstB domain protein ATP-binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 517.0
HKD2_k127_1383977_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 323.0
HKD2_k127_1383977_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 256.0
HKD2_k127_1383977_7 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
HKD2_k127_1383977_8 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000198 220.0
HKD2_k127_1383977_9 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000000000000000000000000000000000000000000166 188.0
HKD2_k127_1387484_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 457.0
HKD2_k127_1387484_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001469 256.0
HKD2_k127_1387484_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000008193 66.0
HKD2_k127_1417280_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 565.0
HKD2_k127_1417280_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 546.0
HKD2_k127_1417280_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 531.0
HKD2_k127_1417280_3 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 509.0
HKD2_k127_1417280_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 419.0
HKD2_k127_1417280_5 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002403 255.0
HKD2_k127_1417280_6 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000001049 121.0
HKD2_k127_142199_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 327.0
HKD2_k127_142199_1 Diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 320.0
HKD2_k127_142199_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 304.0
HKD2_k127_142199_3 PFAM tRNA rRNA methyltransferase (SpoU) K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007221 248.0
HKD2_k127_142199_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000775 210.0
HKD2_k127_142199_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000002609 203.0
HKD2_k127_142199_6 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000001855 72.0
HKD2_k127_1436992_0 Belongs to the SEDS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 570.0
HKD2_k127_1436992_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000521 213.0
HKD2_k127_1436992_2 domain, Protein - - - 0.0000000000000000000000000000000000000000002122 183.0
HKD2_k127_1436992_3 Parallel beta-helix repeats - - - 0.0000000005111 74.0
HKD2_k127_1436992_4 Bacterial Ig-like domain (group 3) - - - 0.00000788 60.0
HKD2_k127_146324_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000006239 227.0
HKD2_k127_146324_1 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000002913 203.0
HKD2_k127_146324_2 CAAX protease self-immunity - - - 0.00000000000000000000001528 104.0
HKD2_k127_1473289_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.574e-318 978.0
HKD2_k127_1473289_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 378.0
HKD2_k127_1473289_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
HKD2_k127_1473289_3 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000000208 166.0
HKD2_k127_1473289_4 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000002525 152.0
HKD2_k127_1473289_6 PFAM CBS domain containing protein - - - 0.000000000000000000000000000004017 124.0
HKD2_k127_1473289_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000001414 79.0
HKD2_k127_1473289_9 AAA domain (dynein-related subfamily) K07452 - - 0.00000000000021 76.0
HKD2_k127_1487326_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004665 282.0
HKD2_k127_1487326_1 Ketopantoate reductase PanE/ApbA K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000002073 242.0
HKD2_k127_1487326_2 cellulase activity K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000001604 186.0
HKD2_k127_1487326_3 transcriptional regulator - - - 0.0000000000000309 81.0
HKD2_k127_1487326_4 Domain of unknown function (DUF333) K14475 - - 0.0000000000004433 82.0
HKD2_k127_1528452_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.146e-271 843.0
HKD2_k127_1528452_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.581e-235 732.0
HKD2_k127_1528452_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 493.0
HKD2_k127_1528452_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 397.0
HKD2_k127_1528452_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
HKD2_k127_1528452_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 328.0
HKD2_k127_1528452_6 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
HKD2_k127_1528452_7 PFAM RNA binding S1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
HKD2_k127_1528452_8 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000001146 227.0
HKD2_k127_1553892_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 584.0
HKD2_k127_1553892_1 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 401.0
HKD2_k127_1553892_10 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000003287 151.0
HKD2_k127_1553892_12 Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000001154 109.0
HKD2_k127_1553892_13 - - - - 0.00001089 53.0
HKD2_k127_1553892_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 360.0
HKD2_k127_1553892_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 362.0
HKD2_k127_1553892_4 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001541 284.0
HKD2_k127_1553892_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
HKD2_k127_1553892_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000002908 215.0
HKD2_k127_1553892_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000001324 208.0
HKD2_k127_1553892_8 CAAX amino Terminal protease family protein K07052 - - 0.0000000000000000000000000000000000000000000000000000000007448 212.0
HKD2_k127_1553892_9 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000177 154.0
HKD2_k127_1554327_0 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 543.0
HKD2_k127_1554327_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 398.0
HKD2_k127_1554327_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000001889 144.0
HKD2_k127_1577116_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.133e-292 905.0
HKD2_k127_1577116_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 2.842e-212 673.0
HKD2_k127_1577116_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000003093 192.0
HKD2_k127_1577116_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000006932 179.0
HKD2_k127_1577116_12 PFAM Calcium calmodulin dependent protein kinase II association-domain protein - - - 0.00000000000000000000000000000000000000000002619 164.0
HKD2_k127_1577116_13 methyltransferase activity K02169 - 2.1.1.197 0.000000000000000000000000000000000000005975 157.0
HKD2_k127_1577116_14 Histidine kinase K07777,K19661,K21405 - 2.7.13.3 0.000000000000000000000000000000005513 146.0
HKD2_k127_1577116_15 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000004629 117.0
HKD2_k127_1577116_16 metallocarboxypeptidase activity K14054 - - 0.000000000000000000009204 104.0
HKD2_k127_1577116_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876,K09759 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
HKD2_k127_1577116_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 511.0
HKD2_k127_1577116_4 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 398.0
HKD2_k127_1577116_5 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 332.0
HKD2_k127_1577116_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 321.0
HKD2_k127_1577116_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000008448 233.0
HKD2_k127_1577116_8 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000005628 215.0
HKD2_k127_1577116_9 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000006925 189.0
HKD2_k127_1589730_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1276.0
HKD2_k127_1589730_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1076.0
HKD2_k127_1589730_10 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 330.0
HKD2_k127_1589730_11 inorganic diphosphatase activity K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
HKD2_k127_1589730_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
HKD2_k127_1589730_13 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 310.0
HKD2_k127_1589730_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
HKD2_k127_1589730_15 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
HKD2_k127_1589730_16 FCD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001601 233.0
HKD2_k127_1589730_17 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000004418 192.0
HKD2_k127_1589730_18 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000000000000000002258 138.0
HKD2_k127_1589730_19 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.000000000000000000000000000000001612 136.0
HKD2_k127_1589730_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.043e-291 905.0
HKD2_k127_1589730_20 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.00000000000000000000000000005161 120.0
HKD2_k127_1589730_21 - - - - 0.000000000000000000000000000601 117.0
HKD2_k127_1589730_23 HTH domain - - - 0.00000001992 63.0
HKD2_k127_1589730_3 Stage II sporulation E family protein - - - 1.024e-286 923.0
HKD2_k127_1589730_4 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 6.382e-280 871.0
HKD2_k127_1589730_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 6.733e-262 817.0
HKD2_k127_1589730_6 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 515.0
HKD2_k127_1589730_7 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 503.0
HKD2_k127_1589730_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 469.0
HKD2_k127_1589730_9 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 345.0
HKD2_k127_1595787_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 307.0
HKD2_k127_1595787_1 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004468 283.0
HKD2_k127_1595787_2 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000000000006944 152.0
HKD2_k127_1595787_3 Bacterial protein of unknown function (DUF916) K00226 - 1.3.98.1 0.00000000001014 76.0
HKD2_k127_1595787_4 PFAM peptidase - - - 0.00000004437 66.0
HKD2_k127_1595787_5 WxL domain surface cell wall-binding - - - 0.0002967 48.0
HKD2_k127_1626253_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 509.0
HKD2_k127_1626253_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 324.0
HKD2_k127_1626253_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000003785 80.0
HKD2_k127_1669637_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 467.0
HKD2_k127_1669637_1 family 4 K01222 - 3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 344.0
HKD2_k127_1669637_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000002763 196.0
HKD2_k127_1669637_3 Subtilase family K17734 - - 0.000000000005188 73.0
HKD2_k127_1671873_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1324.0
HKD2_k127_1671873_1 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 507.0
HKD2_k127_1671873_11 MoeZ MoeB domain K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000002215 93.0
HKD2_k127_1671873_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000004545 73.0
HKD2_k127_1671873_13 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000239 62.0
HKD2_k127_1671873_14 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.00003186 46.0
HKD2_k127_1671873_2 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 425.0
HKD2_k127_1671873_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 406.0
HKD2_k127_1671873_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 364.0
HKD2_k127_1671873_5 PFAM LmbE family protein K18455 - 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 291.0
HKD2_k127_1671873_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000002576 218.0
HKD2_k127_1671873_7 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000001755 164.0
HKD2_k127_1671873_8 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000001611 128.0
HKD2_k127_1671873_9 MazG-like family - - - 0.0000000000000000000000000002885 119.0
HKD2_k127_1737698_0 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 518.0
HKD2_k127_1737698_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 452.0
HKD2_k127_1737698_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 445.0
HKD2_k127_1737698_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 306.0
HKD2_k127_1737698_4 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 256.0
HKD2_k127_1737698_5 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
HKD2_k127_1737698_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000187 155.0
HKD2_k127_1737698_7 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000005325 111.0
HKD2_k127_1737698_8 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000003988 69.0
HKD2_k127_1756859_0 TIGRFAM ATPase, FliI YscN family K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 536.0
HKD2_k127_1756859_1 flagellar motor switch protein FliG K02410 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046982,GO:0046983 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001518 280.0
HKD2_k127_1756859_10 Flagellar assembly protein FliH K02411 - - 0.0000000001438 72.0
HKD2_k127_1756859_11 - - - - 0.0000000002139 70.0
HKD2_k127_1756859_12 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000003293 70.0
HKD2_k127_1756859_13 Flagellar export protein FliJ K02413 - - 0.000359 49.0
HKD2_k127_1756859_2 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007576 275.0
HKD2_k127_1756859_3 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000003864 178.0
HKD2_k127_1756859_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000000000000000000000000000000000000000002848 186.0
HKD2_k127_1756859_5 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000003132 156.0
HKD2_k127_1756859_6 GTPase activity K07901 GO:0000003,GO:0000131,GO:0000166,GO:0000910,GO:0001411,GO:0001882,GO:0001883,GO:0002790,GO:0003006,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005768,GO:0005783,GO:0005886,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0006810,GO:0006887,GO:0006892,GO:0006893,GO:0006903,GO:0006904,GO:0006906,GO:0006914,GO:0006996,GO:0007049,GO:0007107,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009306,GO:0009653,GO:0009987,GO:0010927,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0017157,GO:0019001,GO:0019867,GO:0019953,GO:0022402,GO:0022406,GO:0022413,GO:0022414,GO:0022607,GO:0030133,GO:0030154,GO:0030427,GO:0030435,GO:0030437,GO:0031090,GO:0031321,GO:0031410,GO:0031521,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0031982,GO:0032502,GO:0032505,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0032940,GO:0032989,GO:0032991,GO:0033036,GO:0034293,GO:0034613,GO:0035639,GO:0035690,GO:0036094,GO:0042221,GO:0042493,GO:0042886,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043332,GO:0043934,GO:0043935,GO:0044085,GO:0044237,GO:0044248,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045184,GO:0046903,GO:0048193,GO:0048278,GO:0048284,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051179,GO:0051234,GO:0051286,GO:0051301,GO:0051321,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051704,GO:0051716,GO:0060627,GO:0061024,GO:0061025,GO:0061919,GO:0065007,GO:0070727,GO:0070887,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0090174,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098805,GO:0098876,GO:0120025,GO:0120038,GO:0140029,GO:0140056,GO:1901265,GO:1901363,GO:1903046,GO:1903530,GO:1990778 - 0.000000000000000000000000000000007491 133.0
HKD2_k127_1756859_7 flagellar protein fliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0000000000000000000309 94.0
HKD2_k127_1756859_8 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000001438 86.0
HKD2_k127_1756859_9 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000007631 80.0
HKD2_k127_1819969_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000003377 142.0
HKD2_k127_1853336_0 Metal binding domain of Ada K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000006519 177.0
HKD2_k127_1853336_1 -O-antigen - - - 0.0000000000000000000000000002637 130.0
HKD2_k127_1878971_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 589.0
HKD2_k127_1878971_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 536.0
HKD2_k127_1878971_2 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 403.0
HKD2_k127_1878971_3 heme binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 357.0
HKD2_k127_1878971_4 heme binding K03791,K08642,K21472 - - 0.000000000000000000000000000000000000000000000000000000003857 211.0
HKD2_k127_1878971_6 Cysteine-rich secretory protein family - - - 0.0000000000000000000002481 109.0
HKD2_k127_1878971_7 LysM domain K06194 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000004936 96.0
HKD2_k127_1927144_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.172e-261 815.0
HKD2_k127_1927144_1 Participates in both transcription termination and antitermination K02600 - - 1.925e-218 695.0
HKD2_k127_1927144_10 LysM domain K12204 - - 0.0000005311 61.0
HKD2_k127_1927144_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 329.0
HKD2_k127_1927144_3 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 321.0
HKD2_k127_1927144_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
HKD2_k127_1927144_5 PFAM Diacylglycerol kinase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002306 243.0
HKD2_k127_1927144_6 tRNA pseudouridylate synthase B C-terminal domain K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
HKD2_k127_1927144_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000005887 174.0
HKD2_k127_1927144_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000004084 160.0
HKD2_k127_1927144_9 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000000000000002969 117.0
HKD2_k127_1933034_0 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 354.0
HKD2_k127_1933034_1 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 352.0
HKD2_k127_1933034_10 chromosome segregation - - - 0.0000000000000000000000003025 113.0
HKD2_k127_1933034_11 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000001107 98.0
HKD2_k127_1933034_12 helix_turn_helix, Lux Regulon - - - 0.00000004294 59.0
HKD2_k127_1933034_13 - - - - 0.00000006376 64.0
HKD2_k127_1933034_2 nitronate monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 343.0
HKD2_k127_1933034_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 323.0
HKD2_k127_1933034_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 337.0
HKD2_k127_1933034_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
HKD2_k127_1933034_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
HKD2_k127_1933034_8 - - - - 0.00000000000000000000000000000004857 128.0
HKD2_k127_1933034_9 glyoxalase III activity - - - 0.0000000000000000000000000000007063 130.0
HKD2_k127_197368_0 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000003194 245.0
HKD2_k127_197368_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002528 239.0
HKD2_k127_197368_2 Roadblock/LC7 domain K07131 - - 0.000000000000000000000000000000000000000009982 162.0
HKD2_k127_197368_3 protein serine/threonine phosphatase activity - - - 0.0000000000000000000000000000002677 133.0
HKD2_k127_197368_4 Roadblock/LC7 domain K07131 - - 0.000000000000000000000001817 109.0
HKD2_k127_197368_5 serine threonine protein kinase - - - 0.00000000000000000000002306 105.0
HKD2_k127_197368_6 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000004738 88.0
HKD2_k127_197368_7 - - - - 0.0000000004038 68.0
HKD2_k127_197368_8 response regulator K03406 - - 0.0000000009831 69.0
HKD2_k127_1977034_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 3.368e-204 656.0
HKD2_k127_1977034_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008305 291.0
HKD2_k127_1977034_10 Role in flagellar biosynthesis K02420 - - 0.0000000000000000001292 91.0
HKD2_k127_1977034_11 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process K07699 - - 0.0000001551 58.0
HKD2_k127_1977034_12 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.0000009881 50.0
HKD2_k127_1977034_13 Flagellar biosynthesis protein, FliO K02418 - - 0.00000157 56.0
HKD2_k127_1977034_14 PFAM FlgN - - - 0.000127 51.0
HKD2_k127_1977034_2 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006552 265.0
HKD2_k127_1977034_3 RNA polymerase sigma factor K02405 - - 0.00000000000000000000000000000000000000000000000000000002607 205.0
HKD2_k127_1977034_4 HDOD domain - - - 0.00000000000000000000000000000000000000000000000001455 190.0
HKD2_k127_1977034_5 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000008451 190.0
HKD2_k127_1977034_6 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000001939 183.0
HKD2_k127_1977034_7 flagellar basal-body rod protein K02392 - - 0.0000000000000000000000000000000000000000000001789 177.0
HKD2_k127_1977034_8 SRP54-type protein, GTPase domain K02404 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000954 158.0
HKD2_k127_1977034_9 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K13820 - - 0.00000000000000000000000001623 119.0
HKD2_k127_2004832_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.699e-223 701.0
HKD2_k127_2004832_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 596.0
HKD2_k127_2004832_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007326 259.0
HKD2_k127_2004832_11 succinate dehydrogenase K00241,K00247 - - 0.000000000000000000000000000004687 126.0
HKD2_k127_2004832_12 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000005669 117.0
HKD2_k127_2004832_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 491.0
HKD2_k127_2004832_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 408.0
HKD2_k127_2004832_4 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 410.0
HKD2_k127_2004832_5 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 387.0
HKD2_k127_2004832_6 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 350.0
HKD2_k127_2004832_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HKD2_k127_2004832_8 ABC transporter transmembrane region K02021,K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 288.0
HKD2_k127_2004832_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003281 282.0
HKD2_k127_2006635_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 604.0
HKD2_k127_2006635_1 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 299.0
HKD2_k127_2006635_2 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
HKD2_k127_2006635_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000000000000000000000002175 168.0
HKD2_k127_2006635_4 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000002807 151.0
HKD2_k127_2006635_5 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM - - - 0.00000000000003214 81.0
HKD2_k127_2010900_0 PFAM AAA ATPase central domain protein K07478 - - 6.575e-209 657.0
HKD2_k127_2010900_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 573.0
HKD2_k127_2010900_2 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000004065 150.0
HKD2_k127_2010900_3 - - - - 0.00000000000000000000002721 112.0
HKD2_k127_2010900_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000002845 92.0
HKD2_k127_2010900_5 mRNA binding - - - 0.00000000000001258 78.0
HKD2_k127_2010900_7 Cell wall-associated hydrolases (Invasion-associated proteins) - - - 0.0007951 50.0
HKD2_k127_2065791_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2126.0
HKD2_k127_2065791_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.492e-278 882.0
HKD2_k127_2065791_2 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 410.0
HKD2_k127_2065791_3 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
HKD2_k127_2065791_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000001668 78.0
HKD2_k127_2078072_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 488.0
HKD2_k127_20900_0 Immune inhibitor A peptidase M6 - - - 2.079e-219 700.0
HKD2_k127_20900_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
HKD2_k127_20900_3 PFAM band 7 protein - - - 0.00000000000000000000000000531 110.0
HKD2_k127_20900_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000001459 86.0
HKD2_k127_20900_5 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.0000000001008 68.0
HKD2_k127_20900_6 YtxH-like protein - - - 0.0001018 47.0
HKD2_k127_2101629_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 6.016e-196 622.0
HKD2_k127_2101629_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001957 267.0
HKD2_k127_2101629_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000463 138.0
HKD2_k127_2115703_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 407.0
HKD2_k127_2115703_1 - - - - 0.00000000000000000000001213 103.0
HKD2_k127_2115703_2 peptidyl-tyrosine sulfation - - - 0.00005129 57.0
HKD2_k127_2152373_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 462.0
HKD2_k127_2152373_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 424.0
HKD2_k127_2152373_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 404.0
HKD2_k127_2152373_3 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 395.0
HKD2_k127_2152373_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
HKD2_k127_2152373_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001793 264.0
HKD2_k127_2152373_6 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000005428 237.0
HKD2_k127_2152373_8 - - - - 0.0000000001593 71.0
HKD2_k127_2166743_0 Histidine kinase K07646 - 2.7.13.3 5.595e-291 917.0
HKD2_k127_2166743_1 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 466.0
HKD2_k127_2166743_10 Thiol-disulfide isomerase and thioredoxins - - - 0.0005081 44.0
HKD2_k127_2166743_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 303.0
HKD2_k127_2166743_3 Two component transcriptional regulator, winged helix family K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 298.0
HKD2_k127_2166743_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
HKD2_k127_2166743_5 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000001294 197.0
HKD2_k127_2166743_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000005795 155.0
HKD2_k127_2166743_7 Redoxin - - - 0.00000000000000000000000000000000000001797 146.0
HKD2_k127_2166743_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000002344 101.0
HKD2_k127_2168748_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 356.0
HKD2_k127_2168748_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000005755 263.0
HKD2_k127_2168748_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000009725 106.0
HKD2_k127_2168748_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000003975 108.0
HKD2_k127_2168748_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000005703 106.0
HKD2_k127_2168748_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000003607 72.0
HKD2_k127_2202118_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.116e-220 700.0
HKD2_k127_2202118_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 345.0
HKD2_k127_2202118_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004953 269.0
HKD2_k127_2202118_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000189 147.0
HKD2_k127_2202118_4 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000003388 147.0
HKD2_k127_2215172_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.106e-242 762.0
HKD2_k127_2215172_1 3-carboxyethylcatechol 2,3-dioxygenase activity K04100 - 1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 402.0
HKD2_k127_2215172_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000003007 232.0
HKD2_k127_2215172_3 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000005603 193.0
HKD2_k127_2215172_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000003351 58.0
HKD2_k127_2215172_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000006119 60.0
HKD2_k127_2240394_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008555 259.0
HKD2_k127_2240394_1 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
HKD2_k127_2240394_10 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000003212 76.0
HKD2_k127_2240394_11 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000002815 80.0
HKD2_k127_2240394_12 WD40-like Beta Propeller Repeat - - - 0.00001089 58.0
HKD2_k127_2240394_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003858 252.0
HKD2_k127_2240394_3 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000001986 217.0
HKD2_k127_2240394_4 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000001793 208.0
HKD2_k127_2240394_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000003883 184.0
HKD2_k127_2240394_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000008786 160.0
HKD2_k127_2240394_7 acetyltransferase K00621 - 2.3.1.4 0.00000000000000000000000000000001051 139.0
HKD2_k127_2240394_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000008518 132.0
HKD2_k127_2240394_9 Anti-sigma-K factor rskA - - - 0.000000000000001647 85.0
HKD2_k127_2296145_0 DEAD DEAH box helicase domain protein K06877 - - 3.494e-257 818.0
HKD2_k127_2296145_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 545.0
HKD2_k127_2296145_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 413.0
HKD2_k127_2296145_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 287.0
HKD2_k127_2296145_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000004043 188.0
HKD2_k127_2296145_5 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000002575 111.0
HKD2_k127_2296145_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000001205 67.0
HKD2_k127_2309061_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 7.403e-272 856.0
HKD2_k127_2309061_1 Aldo Keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 506.0
HKD2_k127_2309061_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 446.0
HKD2_k127_2309061_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 386.0
HKD2_k127_2309061_4 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 337.0
HKD2_k127_2309061_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 344.0
HKD2_k127_2309061_6 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 293.0
HKD2_k127_2309061_7 LysM domain - - - 0.00000000000000000000009695 100.0
HKD2_k127_2333057_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 407.0
HKD2_k127_2333057_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001042 258.0
HKD2_k127_2333057_3 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000000000003603 177.0
HKD2_k127_2333057_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000009003 53.0
HKD2_k127_2344481_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
HKD2_k127_2344481_1 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000437 117.0
HKD2_k127_2344481_2 Ankyrin repeat K06867 - - 0.00000000000000000000006372 102.0
HKD2_k127_2359186_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 1.167e-266 831.0
HKD2_k127_2359186_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 545.0
HKD2_k127_2359186_10 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000000004682 241.0
HKD2_k127_2359186_11 membrane-anchored protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002744 180.0
HKD2_k127_2359186_12 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000005752 179.0
HKD2_k127_2359186_2 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 543.0
HKD2_k127_2359186_3 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 524.0
HKD2_k127_2359186_4 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 400.0
HKD2_k127_2359186_5 inositol 2-dehydrogenase activity K18431 - 2.7.7.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 392.0
HKD2_k127_2359186_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 370.0
HKD2_k127_2359186_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
HKD2_k127_2359186_8 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 317.0
HKD2_k127_2359186_9 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 310.0
HKD2_k127_2371509_0 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 323.0
HKD2_k127_2371509_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000002368 199.0
HKD2_k127_2371509_2 COGs COG0524 Sugar kinase ribokinase family - - - 0.000000000000000000000000000000000000000000000002254 184.0
HKD2_k127_2371509_3 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000000003566 179.0
HKD2_k127_2371509_4 phosphatase activity - - - 0.00000000000000000000000000000000000000007738 169.0
HKD2_k127_2371509_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000561 165.0
HKD2_k127_2371509_6 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000001195 149.0
HKD2_k127_2371509_7 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000003834 151.0
HKD2_k127_2371509_8 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.000000000000000000000000000002893 138.0
HKD2_k127_2371509_9 Psort location Cytoplasmic, score 8.96 - - - 0.00003683 53.0
HKD2_k127_2395426_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1026.0
HKD2_k127_2395426_1 A domain family that is part of the cupin metalloenzyme superfamily. K11447 GO:0000578,GO:0000976,GO:0000977,GO:0000978,GO:0000987,GO:0001012,GO:0001067,GO:0001701,GO:0001704,GO:0001707,GO:0001708,GO:0001756,GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002165,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003016,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005700,GO:0005705,GO:0006325,GO:0006338,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006482,GO:0006807,GO:0006928,GO:0006936,GO:0006941,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007369,GO:0007389,GO:0007399,GO:0007423,GO:0007431,GO:0007435,GO:0007498,GO:0007507,GO:0007552,GO:0007585,GO:0008015,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008213,GO:0008214,GO:0008219,GO:0008285,GO:0008593,GO:0009314,GO:0009611,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009798,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009948,GO:0009952,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010212,GO:0010332,GO:0010468,GO:0010506,GO:0010508,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010623,GO:0010628,GO:0010639,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0012501,GO:0012502,GO:0014020,GO:0014070,GO:0016043,GO:0016055,GO:0016331,GO:0016491,GO:0016569,GO:0016570,GO:0016571,GO:0016577,GO:0016705,GO:0016706,GO:0018022,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0021915,GO:0022612,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030048,GO:0030154,GO:0030903,GO:0031056,GO:0031057,GO:0031060,GO:0031061,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031399,GO:0031400,GO:0031490,GO:0031935,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032269,GO:0032451,GO:0032452,GO:0032501,GO:0032502,GO:0032525,GO:0032870,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033554,GO:0033993,GO:0034708,GO:0034968,GO:0035070,GO:0035071,GO:0035072,GO:0035075,GO:0035078,GO:0035081,GO:0035097,GO:0035148,GO:0035239,GO:0035257,GO:0035264,GO:0035272,GO:0035282,GO:0035295,GO:0036211,GO:0036314,GO:0036315,GO:0040007,GO:0042060,GO:0042127,GO:0042221,GO:0042802,GO:0043009,GO:0043067,GO:0043068,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043565,GO:0043618,GO:0043620,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044666,GO:0045165,GO:0045184,GO:0045498,GO:0045746,GO:0045893,GO:0045935,GO:0048102,GO:0048332,GO:0048333,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048570,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048646,GO:0048707,GO:0048729,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051213,GO:0051234,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051276,GO:0051427,GO:0051568,GO:0051716,GO:0051864,GO:0055114,GO:0060033,GO:0060047,GO:0060048,GO:0060070,GO:0060255,GO:0060429,GO:0060562,GO:0060606,GO:0060968,GO:0061053,GO:0061085,GO:0061086,GO:0065007,GO:0070013,GO:0070076,GO:0070252,GO:0070544,GO:0070887,GO:0070988,GO:0071214,GO:0071310,GO:0071390,GO:0071396,GO:0071407,GO:0071478,GO:0071479,GO:0071480,GO:0071495,GO:0071557,GO:0071558,GO:0071704,GO:0071840,GO:0072175,GO:0072358,GO:0072359,GO:0080090,GO:0086003,GO:0097159,GO:0097305,GO:0097306,GO:0098687,GO:0104004,GO:0140096,GO:0198738,GO:1901363,GO:1901564,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902275,GO:1902464,GO:1902465,GO:1902494,GO:1902680,GO:1903506,GO:1903508,GO:1905114,GO:1905268,GO:1990234,GO:1990248,GO:1990837,GO:1990841,GO:2000112,GO:2001141,GO:2001251 - 0.0000606 52.0
HKD2_k127_2411354_0 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 385.0
HKD2_k127_2411354_1 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
HKD2_k127_2411354_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000001335 184.0
HKD2_k127_2411354_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000004201 150.0
HKD2_k127_2411354_4 Methyltransferase domain - - - 0.000000000000000000007576 102.0
HKD2_k127_2434281_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1073.0
HKD2_k127_2434281_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.682e-204 645.0
HKD2_k127_2434281_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.027e-198 631.0
HKD2_k127_2434281_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 429.0
HKD2_k127_2434281_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
HKD2_k127_2434281_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007376 267.0
HKD2_k127_2434281_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000183 136.0
HKD2_k127_2438304_0 import. Responsible for energy coupling to the transport system K10548 - 3.6.3.17 6.171e-241 752.0
HKD2_k127_2438304_1 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 1.094e-195 636.0
HKD2_k127_2438304_2 Periplasmic binding protein domain K10546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 542.0
HKD2_k127_2438304_3 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 514.0
HKD2_k127_2438304_4 Binding-protein-dependent transport system inner membrane component K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 436.0
HKD2_k127_2438304_5 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 350.0
HKD2_k127_2438304_6 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003137 282.0
HKD2_k127_2438304_7 EamA-like transporter family - - - 0.000000001291 61.0
HKD2_k127_2440530_0 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 321.0
HKD2_k127_2440530_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
HKD2_k127_2440530_2 Nacht domain K13730 - - 0.000000000000000000000000000000000000000000000000000000000000009881 236.0
HKD2_k127_2440530_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000003311 181.0
HKD2_k127_2440530_4 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000001763 131.0
HKD2_k127_2440530_5 DUF167 K09131 - - 0.000000000000004677 78.0
HKD2_k127_2440530_6 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000003344 55.0
HKD2_k127_2551373_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 1.323e-310 961.0
HKD2_k127_2551373_1 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 395.0
HKD2_k127_2551373_2 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
HKD2_k127_2551373_3 helix_turn _helix lactose operon repressor K05499 - - 0.0000000000000000000000000000000000000000000000000000179 198.0
HKD2_k127_2566007_0 Permease family K02824 - - 4.463e-221 693.0
HKD2_k127_2566007_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
HKD2_k127_2566007_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
HKD2_k127_2566007_3 PFAM NmrA family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007444 272.0
HKD2_k127_2566007_4 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
HKD2_k127_2566007_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000002301 233.0
HKD2_k127_2566007_6 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000000000000000000000008498 172.0
HKD2_k127_259877_0 PFAM type II secretion system protein E K02283 - - 2.072e-216 679.0
HKD2_k127_259877_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 452.0
HKD2_k127_259877_2 PFAM type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 442.0
HKD2_k127_259877_3 PFAM type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
HKD2_k127_259877_4 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 301.0
HKD2_k127_2608374_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.415e-310 974.0
HKD2_k127_2608374_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 612.0
HKD2_k127_2608374_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 482.0
HKD2_k127_2608374_3 Sugar (and other) transporter K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002967 281.0
HKD2_k127_2608374_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 274.0
HKD2_k127_2608374_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003466 250.0
HKD2_k127_2608374_6 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004989 243.0
HKD2_k127_2608374_7 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000009681 182.0
HKD2_k127_2644537_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.864e-226 721.0
HKD2_k127_2644537_1 amino acid-binding ACT domain protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 304.0
HKD2_k127_2644537_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000001047 222.0
HKD2_k127_2644537_3 RF-1 domain K15034 - - 0.000000000000000000000000000000005627 133.0
HKD2_k127_2644537_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000004656 113.0
HKD2_k127_2644537_5 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000002344 98.0
HKD2_k127_266447_0 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 304.0
HKD2_k127_266447_1 Serine Threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000004051 195.0
HKD2_k127_266447_2 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.0000000000004662 70.0
HKD2_k127_266447_3 response to heat K03668,K09914 - - 0.00000000003162 74.0
HKD2_k127_2698355_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 3.765e-311 967.0
HKD2_k127_2698355_1 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 1.843e-270 845.0
HKD2_k127_2698355_10 Osmosensitive K channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000006924 255.0
HKD2_k127_2698355_11 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000008919 241.0
HKD2_k127_2698355_12 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
HKD2_k127_2698355_13 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000002449 212.0
HKD2_k127_2698355_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000001116 170.0
HKD2_k127_2698355_15 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000001408 146.0
HKD2_k127_2698355_16 HNH endonuclease K07451,K07453 - - 0.00000000000000006364 84.0
HKD2_k127_2698355_17 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000464 88.0
HKD2_k127_2698355_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.983e-253 809.0
HKD2_k127_2698355_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 593.0
HKD2_k127_2698355_4 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 582.0
HKD2_k127_2698355_5 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 571.0
HKD2_k127_2698355_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 463.0
HKD2_k127_2698355_7 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 329.0
HKD2_k127_2698355_8 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 297.0
HKD2_k127_2698355_9 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007111 265.0
HKD2_k127_2702903_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 526.0
HKD2_k127_2702903_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 344.0
HKD2_k127_2702903_3 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004981 237.0
HKD2_k127_2702903_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000004544 54.0
HKD2_k127_2705548_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 341.0
HKD2_k127_2705548_1 membrane protein involved in D-alanine K19294 - - 0.000000000000000000000000000000000000000000000000000000000000007289 235.0
HKD2_k127_2705548_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000001996 173.0
HKD2_k127_2705548_3 Domain of unknown function (DUF4203) - - - 0.000000000000000000001023 102.0
HKD2_k127_2705548_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000007971 84.0
HKD2_k127_2705548_6 - - - - 0.0001363 53.0
HKD2_k127_2733968_0 Putative cyclase - - - 1.484e-311 960.0
HKD2_k127_2733968_1 CoA-ligase K02381 - - 9.999e-237 746.0
HKD2_k127_2733968_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 2.619e-235 734.0
HKD2_k127_2733968_3 Protein of unknown function (DUF1116) - - - 7.942e-195 614.0
HKD2_k127_2733968_4 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 359.0
HKD2_k127_2733968_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001216 281.0
HKD2_k127_2733968_6 xanthine dehydrogenase activity K03519,K19818 - 1.2.5.3,1.5.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
HKD2_k127_2733968_7 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
HKD2_k127_2733968_8 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000145 105.0
HKD2_k127_2745142_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 566.0
HKD2_k127_2745142_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 452.0
HKD2_k127_2745142_2 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006136 256.0
HKD2_k127_2745142_3 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006349 255.0
HKD2_k127_2745142_4 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 246.0
HKD2_k127_2745142_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000001092 164.0
HKD2_k127_2745142_8 Redoxin - - - 0.0000000001368 63.0
HKD2_k127_2745142_9 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.000001881 60.0
HKD2_k127_2754389_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 5.522e-201 637.0
HKD2_k127_2754389_1 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 606.0
HKD2_k127_2754389_10 CoA binding domain - - - 0.000000000003485 72.0
HKD2_k127_2754389_11 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000932 70.0
HKD2_k127_2754389_2 Oxidoreductase family, C-terminal alpha beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 424.0
HKD2_k127_2754389_3 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 394.0
HKD2_k127_2754389_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 355.0
HKD2_k127_2754389_5 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 355.0
HKD2_k127_2754389_6 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 322.0
HKD2_k127_2754389_7 myo-inosose-2 dehydratase activity K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
HKD2_k127_2754389_8 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 282.0
HKD2_k127_2754389_9 COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007068 267.0
HKD2_k127_277621_0 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000001305 178.0
HKD2_k127_277621_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000009237 124.0
HKD2_k127_277621_2 - - - - 0.0000006973 59.0
HKD2_k127_277621_3 Protein of unknown function (DUF1706) - - - 0.0000898 51.0
HKD2_k127_2795910_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 334.0
HKD2_k127_2795910_1 acetyltransferase - - - 0.000000000000000000000000000000000000000002321 162.0
HKD2_k127_2795910_2 Elongation factor K02355 - - 0.0004566 43.0
HKD2_k127_2800250_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 603.0
HKD2_k127_2800250_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
HKD2_k127_2800250_2 agmatine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 520.0
HKD2_k127_2800250_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 463.0
HKD2_k127_2817004_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.451e-270 847.0
HKD2_k127_2817004_1 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 359.0
HKD2_k127_2817004_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004862 279.0
HKD2_k127_2818350_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 564.0
HKD2_k127_2818350_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 507.0
HKD2_k127_2818350_2 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 265.0
HKD2_k127_2818350_3 B3 4 domain protein - - - 0.00000000000000000000000000000000000000000000000000003139 195.0
HKD2_k127_2818350_4 PFAM Stage V sporulation protein S K06416 - - 0.00000000000000000000000000000000000002607 145.0
HKD2_k127_2818350_6 4Fe-4S dicluster domain - - - 0.00000000000000000000009411 98.0
HKD2_k127_2819320_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 539.0
HKD2_k127_2819320_1 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 385.0
HKD2_k127_2819320_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006862 276.0
HKD2_k127_2819320_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000001835 177.0
HKD2_k127_2819320_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000004445 80.0
HKD2_k127_2819432_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.761e-249 782.0
HKD2_k127_2819432_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 482.0
HKD2_k127_2819432_2 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 458.0
HKD2_k127_2819432_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 438.0
HKD2_k127_2819432_4 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 293.0
HKD2_k127_2819432_6 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000006964 115.0
HKD2_k127_2833858_0 Flagella basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 312.0
HKD2_k127_2833858_1 Flagellar biosynthesis protein - - - 0.0000000000000000000001868 102.0
HKD2_k127_2833858_2 FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000006507 98.0
HKD2_k127_2833858_3 Bacterial flagellin N-terminal helical region K02397 - - 0.00000000000000000004737 101.0
HKD2_k127_2833858_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000001815 80.0
HKD2_k127_2833858_5 Flagellar hook capping protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.000000000007541 71.0
HKD2_k127_2833858_6 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.000000001147 59.0
HKD2_k127_2833858_7 Flagellar hook-length control protein K02414 - - 0.000003525 59.0
HKD2_k127_2833858_8 - - - - 0.000009455 53.0
HKD2_k127_2833858_9 - - - - 0.000356 53.0
HKD2_k127_2863061_0 Family 4 glycosyl hydrolase C-terminal domain K01222,K07406 - 3.2.1.22,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 513.0
HKD2_k127_2863061_1 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 337.0
HKD2_k127_2863061_2 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 317.0
HKD2_k127_2863061_3 Binding-protein-dependent transport system inner membrane component K10119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 317.0
HKD2_k127_2863061_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 315.0
HKD2_k127_2863061_5 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002331 284.0
HKD2_k127_2863061_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
HKD2_k127_2863061_8 Bacterial extracellular solute-binding protein K10117 - - 0.00000000000000000003964 93.0
HKD2_k127_2864299_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 3.666e-208 658.0
HKD2_k127_2864299_1 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 486.0
HKD2_k127_2864299_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000001646 54.0
HKD2_k127_2864299_2 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 463.0
HKD2_k127_2864299_3 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 389.0
HKD2_k127_2864299_4 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 334.0
HKD2_k127_2864299_5 COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 327.0
HKD2_k127_2864299_6 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003436 270.0
HKD2_k127_2864299_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000007467 198.0
HKD2_k127_2864299_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.000000000000000000000000000001656 131.0
HKD2_k127_2864299_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000002268 117.0
HKD2_k127_2928735_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.022e-217 679.0
HKD2_k127_2928735_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 362.0
HKD2_k127_2928735_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000001421 221.0
HKD2_k127_2928735_3 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000001784 211.0
HKD2_k127_2928735_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000003018 184.0
HKD2_k127_2928735_6 - - - - 0.0009593 44.0
HKD2_k127_2978925_0 PFAM magnesium chelatase ChlI subunit K07391 - - 3.74e-241 754.0
HKD2_k127_2978925_1 membrane K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000003541 231.0
HKD2_k127_2978925_2 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
HKD2_k127_2978925_3 PFAM pentapeptide repeat protein - - - 0.0000000000000000000000000000000000000000000000000000006628 197.0
HKD2_k127_2978925_4 - - - - 0.00000000000000000001015 99.0
HKD2_k127_2978925_5 pentapeptide repeat protein - - - 0.00001345 52.0
HKD2_k127_2999_0 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 386.0
HKD2_k127_2999_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000002493 222.0
HKD2_k127_302187_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.487e-213 670.0
HKD2_k127_302187_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 467.0
HKD2_k127_302187_10 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000002445 177.0
HKD2_k127_302187_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000007905 159.0
HKD2_k127_302187_12 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000001525 128.0
HKD2_k127_302187_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000009675 115.0
HKD2_k127_302187_14 periplasmic binding protein K02016 - - 0.00000000000000000000005108 105.0
HKD2_k127_302187_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000004776 100.0
HKD2_k127_302187_16 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000353 61.0
HKD2_k127_302187_17 - - - - 0.0000006007 57.0
HKD2_k127_302187_18 - - - - 0.00009109 52.0
HKD2_k127_302187_19 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.0002116 52.0
HKD2_k127_302187_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 458.0
HKD2_k127_302187_20 nucleotide catabolic process - - - 0.0006487 51.0
HKD2_k127_302187_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 399.0
HKD2_k127_302187_4 Glycogen debranching enzyme, glucanotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 393.0
HKD2_k127_302187_5 PFAM ABC transporter related K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 361.0
HKD2_k127_302187_6 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
HKD2_k127_302187_7 diguanylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003323 249.0
HKD2_k127_302187_8 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000007256 210.0
HKD2_k127_302187_9 - - - - 0.000000000000000000000000000000000000000000000002469 191.0
HKD2_k127_3022609_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000001521 189.0
HKD2_k127_3022609_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000004687 130.0
HKD2_k127_3022609_2 - - - - 0.0000000003171 72.0
HKD2_k127_3045385_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 6.857e-273 850.0
HKD2_k127_3045385_1 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 415.0
HKD2_k127_3045385_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 343.0
HKD2_k127_3045385_3 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 303.0
HKD2_k127_3045385_4 LysM domain K02020 - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
HKD2_k127_3045385_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000006971 183.0
HKD2_k127_3045385_6 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000001103 157.0
HKD2_k127_3045385_7 Zinc-uptake complex component A periplasmic K09815,K11707 - - 0.0000000000000906 76.0
HKD2_k127_3052860_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4e-323 1000.0
HKD2_k127_3052860_1 PFAM ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 497.0
HKD2_k127_3052860_10 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000007213 83.0
HKD2_k127_3052860_2 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 437.0
HKD2_k127_3052860_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 382.0
HKD2_k127_3052860_4 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 334.0
HKD2_k127_3052860_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
HKD2_k127_3052860_6 ECF transporter, substrate-specific component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002607 233.0
HKD2_k127_3052860_7 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000165 204.0
HKD2_k127_3052860_8 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000003122 180.0
HKD2_k127_3052860_9 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000002039 173.0
HKD2_k127_3072837_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1847.0
HKD2_k127_3072837_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1103.0
HKD2_k127_3072837_10 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000002586 169.0
HKD2_k127_3072837_11 GrpB protein - - - 0.0000000000000000000000000000000000000000006355 164.0
HKD2_k127_3072837_12 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000000000000000000000000000001627 130.0
HKD2_k127_3072837_13 LysM domain K07273,K22278 - 3.5.1.104 0.0000000000000000000000000000007364 131.0
HKD2_k127_3072837_14 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000009549 134.0
HKD2_k127_3072837_15 elongation factor Tu domain 2 protein K06207 - - 0.000000000000000000000000000001281 121.0
HKD2_k127_3072837_16 TIGRFAM redox-active disulfide protein 2 - - - 0.00000000000000000000000000001363 119.0
HKD2_k127_3072837_17 - K07566 - 2.7.7.87 0.0000002885 58.0
HKD2_k127_3072837_2 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 2.549e-305 956.0
HKD2_k127_3072837_3 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 436.0
HKD2_k127_3072837_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 425.0
HKD2_k127_3072837_5 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 420.0
HKD2_k127_3072837_6 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
HKD2_k127_3072837_7 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 350.0
HKD2_k127_3072837_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000438 250.0
HKD2_k127_3072837_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000001813 226.0
HKD2_k127_3089768_0 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
HKD2_k127_3089768_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 544.0
HKD2_k127_3089768_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
HKD2_k127_3089768_3 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 344.0
HKD2_k127_3089768_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 325.0
HKD2_k127_3089768_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HKD2_k127_3089768_6 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002028 260.0
HKD2_k127_3089768_7 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000002971 149.0
HKD2_k127_3089768_8 PFAM Methicillin resistance protein - - - 0.0000000000000000000007678 101.0
HKD2_k127_3107951_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 397.0
HKD2_k127_3107951_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
HKD2_k127_3107951_2 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.000000000000000000000000000000000000000000000000000000000000000000003894 250.0
HKD2_k127_3107951_3 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000008008 198.0
HKD2_k127_3107951_4 Transcriptional regulator K03603,K05799 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000443 149.0
HKD2_k127_3107951_5 - K14340 - - 0.00000000000000000000000008078 112.0
HKD2_k127_3126001_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.948e-222 693.0
HKD2_k127_3126001_1 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 580.0
HKD2_k127_3126001_10 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000004439 188.0
HKD2_k127_3126001_11 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000009351 164.0
HKD2_k127_3126001_12 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000001323 139.0
HKD2_k127_3126001_13 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000008604 116.0
HKD2_k127_3126001_14 HlyD family secretion protein K02005 - - 0.000000000000001656 89.0
HKD2_k127_3126001_15 Transglycosylase associated protein - - - 0.00000000000000206 79.0
HKD2_k127_3126001_2 Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 587.0
HKD2_k127_3126001_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 494.0
HKD2_k127_3126001_4 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 429.0
HKD2_k127_3126001_5 Efflux ABC transporter permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 334.0
HKD2_k127_3126001_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 334.0
HKD2_k127_3126001_7 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004786 282.0
HKD2_k127_3126001_8 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000008623 253.0
HKD2_k127_3126001_9 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000007304 240.0
HKD2_k127_315931_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.367e-219 695.0
HKD2_k127_315931_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 511.0
HKD2_k127_315931_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000007774 169.0
HKD2_k127_315931_11 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000002882 124.0
HKD2_k127_315931_12 Septum formation initiator - - - 0.00000000000001723 79.0
HKD2_k127_315931_13 Tyrosine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000001714 64.0
HKD2_k127_315931_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 488.0
HKD2_k127_315931_3 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 393.0
HKD2_k127_315931_4 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 376.0
HKD2_k127_315931_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 305.0
HKD2_k127_315931_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
HKD2_k127_315931_7 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000000000000000003949 236.0
HKD2_k127_315931_8 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000004496 183.0
HKD2_k127_315931_9 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000002366 170.0
HKD2_k127_3192303_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000007448 212.0
HKD2_k127_3192303_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000001974 198.0
HKD2_k127_3192303_2 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000000000000004416 156.0
HKD2_k127_3192303_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000002133 142.0
HKD2_k127_3192303_4 transcriptional K07729 - - 0.0000000000000000001416 91.0
HKD2_k127_3327136_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1068.0
HKD2_k127_3327136_1 PFAM Transketolase central region K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 455.0
HKD2_k127_3327136_10 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 311.0
HKD2_k127_3327136_11 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 309.0
HKD2_k127_3327136_12 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 300.0
HKD2_k127_3327136_13 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 289.0
HKD2_k127_3327136_14 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000038 285.0
HKD2_k127_3327136_16 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
HKD2_k127_3327136_17 - - - - 0.000000000000000000000000000000000000000000000000000000000002361 216.0
HKD2_k127_3327136_18 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000005183 221.0
HKD2_k127_3327136_19 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000001183 206.0
HKD2_k127_3327136_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 442.0
HKD2_k127_3327136_20 PFAM AzlC family protein - - - 0.000000000000000000000000000000000000000000000000000004808 196.0
HKD2_k127_3327136_21 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000001593 156.0
HKD2_k127_3327136_23 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000007347 108.0
HKD2_k127_3327136_24 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000001784 91.0
HKD2_k127_3327136_25 branched-chain amino acid - - - 0.0000000000000003361 81.0
HKD2_k127_3327136_26 mercury ion transmembrane transporter activity K07213 - - 0.000000000000004102 78.0
HKD2_k127_3327136_3 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 392.0
HKD2_k127_3327136_4 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 385.0
HKD2_k127_3327136_5 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 360.0
HKD2_k127_3327136_6 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 358.0
HKD2_k127_3327136_7 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 343.0
HKD2_k127_3327136_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 322.0
HKD2_k127_3327136_9 Biogenesis protein K02275,K09792,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 320.0
HKD2_k127_3354634_0 ATPase AAA-2 domain protein K03696 - - 0.0 1188.0
HKD2_k127_3354634_1 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 4.932e-253 797.0
HKD2_k127_3354634_10 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 280.0
HKD2_k127_3354634_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006229 270.0
HKD2_k127_3354634_12 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000001053 198.0
HKD2_k127_3354634_13 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000003425 186.0
HKD2_k127_3354634_14 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000005705 188.0
HKD2_k127_3354634_15 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000001063 173.0
HKD2_k127_3354634_16 TIGRFAM DNA binding domain - - - 0.000000000000000000000000000000000000000000008528 171.0
HKD2_k127_3354634_17 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000002957 153.0
HKD2_k127_3354634_18 transcription activator, effector binding - - - 0.000000000000000000000000000000000000001806 152.0
HKD2_k127_3354634_19 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000042 135.0
HKD2_k127_3354634_2 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 8.172e-234 738.0
HKD2_k127_3354634_20 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000000000001195 126.0
HKD2_k127_3354634_21 Phospholipid methyltransferase - - - 0.0000000000000000007556 95.0
HKD2_k127_3354634_3 PFAM VanW family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 597.0
HKD2_k127_3354634_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 530.0
HKD2_k127_3354634_5 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 501.0
HKD2_k127_3354634_6 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 447.0
HKD2_k127_3354634_7 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 412.0
HKD2_k127_3354634_8 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 316.0
HKD2_k127_3354634_9 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
HKD2_k127_3361396_0 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 613.0
HKD2_k127_3361396_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 586.0
HKD2_k127_3361396_10 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002441 280.0
HKD2_k127_3361396_11 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000003597 260.0
HKD2_k127_3361396_12 PFAM glutamine amidotransferase class-I K07010 - - 0.0000000000000000000000000000000000000000000000000000000000001223 222.0
HKD2_k127_3361396_13 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000009276 207.0
HKD2_k127_3361396_14 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000003758 183.0
HKD2_k127_3361396_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000002974 175.0
HKD2_k127_3361396_16 carbon monoxide dehydrogenase small subunit K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000007332 173.0
HKD2_k127_3361396_17 dihydrofolate reductase - - - 0.0000000000000000000000000000000000000000000004908 172.0
HKD2_k127_3361396_18 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000001292 173.0
HKD2_k127_3361396_19 acetyltransferase - - - 0.000000000000000000000000000000000000000005954 159.0
HKD2_k127_3361396_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 542.0
HKD2_k127_3361396_20 arylsulfatase activity - - - 0.000000000000000000003272 108.0
HKD2_k127_3361396_21 Pfam:DUF385 - - - 0.0000009088 59.0
HKD2_k127_3361396_22 - - - - 0.0001233 46.0
HKD2_k127_3361396_3 ABC transporter substrate-binding protein PnrA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 509.0
HKD2_k127_3361396_4 DNA photolyase domain protein K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 497.0
HKD2_k127_3361396_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 457.0
HKD2_k127_3361396_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 431.0
HKD2_k127_3361396_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 306.0
HKD2_k127_3361396_8 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 290.0
HKD2_k127_3361396_9 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 289.0
HKD2_k127_3365180_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 5.472e-210 663.0
HKD2_k127_3365180_1 AAA domain K02282 - - 0.000000000000000000002379 98.0
HKD2_k127_3416299_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.579e-229 740.0
HKD2_k127_3416299_1 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 1.032e-210 663.0
HKD2_k127_3416299_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 606.0
HKD2_k127_3416299_3 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 572.0
HKD2_k127_3416299_4 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005831 289.0
HKD2_k127_3416299_5 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000000001148 124.0
HKD2_k127_3416299_6 THIoesterase - - - 0.00000000000000000000000000003118 121.0
HKD2_k127_3416299_7 Major Facilitator Superfamily - - - 0.000000000004356 68.0
HKD2_k127_3426009_0 PFAM 4Fe-4S K00184,K21308 - - 6.83e-315 992.0
HKD2_k127_3426009_1 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 1.221e-203 649.0
HKD2_k127_3426009_10 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000003108 235.0
HKD2_k127_3426009_11 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.000000000000000000000000000000000000000000000000003171 188.0
HKD2_k127_3426009_12 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000003464 190.0
HKD2_k127_3426009_13 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000003257 169.0
HKD2_k127_3426009_14 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000002511 162.0
HKD2_k127_3426009_15 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000000000000001772 149.0
HKD2_k127_3426009_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000007449 120.0
HKD2_k127_3426009_17 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000000000000000001101 108.0
HKD2_k127_3426009_2 Polysulphide reductase, NrfD K00185 - - 2.809e-199 630.0
HKD2_k127_3426009_3 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 562.0
HKD2_k127_3426009_4 belongs to the aldehyde dehydrogenase family K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 535.0
HKD2_k127_3426009_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 481.0
HKD2_k127_3426009_6 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 398.0
HKD2_k127_3426009_7 deoxyribose-phosphate aldolase activity K00852,K01619,K01840,K01844 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.1.15,4.1.2.4,5.4.2.8,5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 300.0
HKD2_k127_3426009_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 293.0
HKD2_k127_3426009_9 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 293.0
HKD2_k127_349762_0 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 563.0
HKD2_k127_349762_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 531.0
HKD2_k127_349762_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
HKD2_k127_3518242_0 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000004996 219.0
HKD2_k127_3518242_1 Diguanylate cyclase - - - 0.000000000000000000000000000000006041 131.0
HKD2_k127_3518242_2 protein conserved in bacteria - - - 0.00000002762 63.0
HKD2_k127_3528675_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.901e-259 807.0
HKD2_k127_3528675_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 496.0
HKD2_k127_3528675_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000001728 220.0
HKD2_k127_3528675_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000004394 218.0
HKD2_k127_3528675_4 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000682 219.0
HKD2_k127_3528675_5 protein homooligomerization - - - 0.0000000000000000000000000000000000000000000000007175 182.0
HKD2_k127_3528675_6 Protein of unknown function with HXXEE motif - - - 0.0000000000000000000000000000000000000000005455 163.0
HKD2_k127_3528675_7 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000006971 134.0
HKD2_k127_3532061_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.445e-260 832.0
HKD2_k127_3532061_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 325.0
HKD2_k127_3532061_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 240.0
HKD2_k127_3532061_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000002106 94.0
HKD2_k127_35382_0 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 498.0
HKD2_k127_35382_1 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 349.0
HKD2_k127_35382_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003629 273.0
HKD2_k127_3546485_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.08e-201 638.0
HKD2_k127_3546485_1 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 292.0
HKD2_k127_3546485_2 transmembrane transporter activity K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006746 281.0
HKD2_k127_3546485_3 dolichyl monophosphate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 247.0
HKD2_k127_3546485_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
HKD2_k127_3546485_5 sh3 domain protein K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000106 172.0
HKD2_k127_3546485_6 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000001084 110.0
HKD2_k127_3546485_8 SPFH domain-Band 7 family - - - 0.00007927 52.0
HKD2_k127_3603592_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 387.0
HKD2_k127_3603592_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000008612 225.0
HKD2_k127_3603592_2 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
HKD2_k127_3603592_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000133 157.0
HKD2_k127_3603592_4 Putative regulatory protein - - - 0.00000000000000000000000000000001714 130.0
HKD2_k127_3658086_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.358e-204 644.0
HKD2_k127_3658086_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 475.0
HKD2_k127_3658086_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 313.0
HKD2_k127_3658086_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 301.0
HKD2_k127_3658086_4 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001752 294.0
HKD2_k127_3658086_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000002277 232.0
HKD2_k127_3658086_6 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000001508 193.0
HKD2_k127_3658086_7 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000001998 183.0
HKD2_k127_3658086_8 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000004646 163.0
HKD2_k127_3658086_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000001454 118.0
HKD2_k127_3677043_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000303 184.0
HKD2_k127_3677043_1 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000008026 119.0
HKD2_k127_3677043_2 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000008691 114.0
HKD2_k127_3677043_3 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000105 109.0
HKD2_k127_3677043_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000001445 99.0
HKD2_k127_3686021_0 ABC transporter K02056,K10441 - 3.6.3.17 5.966e-213 673.0
HKD2_k127_3686021_1 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 474.0
HKD2_k127_3686021_2 PFAM periplasmic binding protein LacI transcriptional regulator K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 455.0
HKD2_k127_3686021_3 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000001407 186.0
HKD2_k127_3715144_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 514.0
HKD2_k127_3715144_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 420.0
HKD2_k127_3715144_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000005184 117.0
HKD2_k127_3732251_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.915e-277 877.0
HKD2_k127_3732251_1 Rieske (2Fe-2S) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 379.0
HKD2_k127_3732251_2 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 351.0
HKD2_k127_3732251_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002632 283.0
HKD2_k127_3732251_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000001157 172.0
HKD2_k127_3732251_5 galactitol metabolic process K02775,K16371,K21622 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 5.1.3.40 0.0001269 48.0
HKD2_k127_3744143_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.406e-205 646.0
HKD2_k127_3744143_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 518.0
HKD2_k127_3744143_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000045 258.0
HKD2_k127_3744143_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000003217 247.0
HKD2_k127_3744143_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000011 235.0
HKD2_k127_3744143_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000009651 231.0
HKD2_k127_3744143_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002455 227.0
HKD2_k127_3744143_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004679 210.0
HKD2_k127_3744143_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001692 207.0
HKD2_k127_3744143_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000004672 206.0
HKD2_k127_3744143_18 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001001 189.0
HKD2_k127_3744143_19 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD2_k127_3744143_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 479.0
HKD2_k127_3744143_20 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001069 179.0
HKD2_k127_3744143_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000004788 175.0
HKD2_k127_3744143_22 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000006949 168.0
HKD2_k127_3744143_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000004809 162.0
HKD2_k127_3744143_24 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000009609 159.0
HKD2_k127_3744143_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000006843 144.0
HKD2_k127_3744143_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000001777 122.0
HKD2_k127_3744143_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000005563 113.0
HKD2_k127_3744143_28 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000007957 85.0
HKD2_k127_3744143_29 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002529 83.0
HKD2_k127_3744143_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 369.0
HKD2_k127_3744143_30 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000007479 79.0
HKD2_k127_3744143_31 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000002084 67.0
HKD2_k127_3744143_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 358.0
HKD2_k127_3744143_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 310.0
HKD2_k127_3744143_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 303.0
HKD2_k127_3744143_7 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 291.0
HKD2_k127_3744143_8 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 288.0
HKD2_k127_3744143_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
HKD2_k127_3772263_0 PFAM glycosyl transferase, family 51 - - - 0.0 1104.0
HKD2_k127_3772263_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.492e-271 848.0
HKD2_k127_3772263_11 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000001699 211.0
HKD2_k127_3772263_14 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000000000000006461 159.0
HKD2_k127_3772263_15 - - - - 0.0000000000000000000000000000000000000002957 153.0
HKD2_k127_3772263_16 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000000000002705 138.0
HKD2_k127_3772263_17 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000006211 124.0
HKD2_k127_3772263_18 Cyclic-di-AMP receptor - - - 0.0000000000000000000000001493 108.0
HKD2_k127_3772263_19 proteolysis K21140 - 3.13.1.6 0.0000000000000000006671 91.0
HKD2_k127_3772263_2 His Kinase A (phosphoacceptor) domain - - - 7.793e-197 625.0
HKD2_k127_3772263_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 589.0
HKD2_k127_3772263_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 423.0
HKD2_k127_3772263_5 CpXC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 410.0
HKD2_k127_3772263_6 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 297.0
HKD2_k127_3772263_7 PFAM Thioredoxin domain K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002623 282.0
HKD2_k127_3772263_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001671 257.0
HKD2_k127_3772263_9 ferrous iron binding K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000198 237.0
HKD2_k127_3778435_0 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 515.0
HKD2_k127_3778435_1 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 493.0
HKD2_k127_3778435_2 aminoglycoside K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 322.0
HKD2_k127_3778435_3 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 286.0
HKD2_k127_3778435_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
HKD2_k127_3778435_5 Rubrerythrin K22336 - 1.16.3.1 0.00000000000000000000000000000000000000000000928 168.0
HKD2_k127_3778435_6 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000000000005362 120.0
HKD2_k127_3792305_0 Major facilitator Superfamily K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 395.0
HKD2_k127_3792305_1 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 302.0
HKD2_k127_3792305_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
HKD2_k127_3792305_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000002515 137.0
HKD2_k127_3792305_4 - - - - 0.000000000000000000002057 97.0
HKD2_k127_3824067_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004641 260.0
HKD2_k127_3824067_1 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005551 260.0
HKD2_k127_3824067_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000007861 149.0
HKD2_k127_38344_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 579.0
HKD2_k127_38344_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 384.0
HKD2_k127_38344_2 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 381.0
HKD2_k127_38344_3 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 342.0
HKD2_k127_38344_4 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000000000000000001971 144.0
HKD2_k127_38344_5 heavy metal translocating P-type ATPase K01534 - 3.6.3.3,3.6.3.5 0.000001378 53.0
HKD2_k127_3882657_0 Psort location CytoplasmicMembrane, score K16786,K16787 - - 1.48e-263 822.0
HKD2_k127_3882657_1 cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 388.0
HKD2_k127_3882657_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 318.0
HKD2_k127_3882657_3 Pfam:DUF3816 K16924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 313.0
HKD2_k127_3897899_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 8.136e-208 665.0
HKD2_k127_3897899_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000005238 233.0
HKD2_k127_3897899_2 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000001193 229.0
HKD2_k127_3897899_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.000000000000000000000000000000000000000000000000000004417 196.0
HKD2_k127_3897899_4 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000005987 141.0
HKD2_k127_3897899_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000004091 147.0
HKD2_k127_3897899_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000991 118.0
HKD2_k127_4002193_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 345.0
HKD2_k127_4002193_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
HKD2_k127_4002193_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000006327 222.0
HKD2_k127_4002193_4 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000006167 110.0
HKD2_k127_4124635_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 1.299e-203 639.0
HKD2_k127_4124635_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 575.0
HKD2_k127_4124635_2 Aldehyde dehydrogenase family K15515,K18119 - 1.2.1.76,1.2.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 472.0
HKD2_k127_4124635_3 Domain of unknown function (DUF4203) - - - 0.0000000000000000000000000000003397 129.0
HKD2_k127_4124635_5 methyltransferase activity - - - 0.0000000000000297 80.0
HKD2_k127_4164500_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 1.103e-202 642.0
HKD2_k127_4164500_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 456.0
HKD2_k127_4164500_2 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
HKD2_k127_4164500_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001447 283.0
HKD2_k127_4164500_4 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000009126 108.0
HKD2_k127_4164500_5 EF-hand domain pair - - - 0.0000001415 59.0
HKD2_k127_4190526_0 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 0.0 1011.0
HKD2_k127_4190526_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00335,K05587 - 1.6.5.3 8.916e-212 663.0
HKD2_k127_4190526_10 Ferredoxin K00335,K17992 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000001032 137.0
HKD2_k127_4190526_11 DRTGG domain - - - 0.000000000000000000000000000000001814 134.0
HKD2_k127_4190526_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
HKD2_k127_4190526_3 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 401.0
HKD2_k127_4190526_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001026 266.0
HKD2_k127_4190526_5 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000003451 256.0
HKD2_k127_4190526_6 phosphorelay sensor kinase activity K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000008533 202.0
HKD2_k127_4190526_7 2 iron, 2 sulfur cluster binding K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000003298 184.0
HKD2_k127_4190526_8 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000001409 179.0
HKD2_k127_4190526_9 DRTGG domain - - - 0.00000000000000000000000000000000000000007018 154.0
HKD2_k127_4213283_0 Transcriptional regulator of aromatic amino acids metabolism K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 370.0
HKD2_k127_4213283_2 PFAM TadE family protein K12287 - - 0.000000000000000000000000000000000005251 156.0
HKD2_k127_4213283_3 PFAM TadE family protein - - - 0.00000000000006631 80.0
HKD2_k127_4232089_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 334.0
HKD2_k127_4232089_1 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002425 272.0
HKD2_k127_4232089_2 Ig-like domain from next to BRCA1 gene K13276 - - 0.0000000000000000000000000000000000000005941 158.0
HKD2_k127_4232089_3 organic phosphonate transport K02044 - - 0.000003462 50.0
HKD2_k127_4242031_0 -O-antigen K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000001032 239.0
HKD2_k127_4242031_1 virulence factor MVIN family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005283 238.0
HKD2_k127_4242031_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000005209 208.0
HKD2_k127_4242031_3 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000001707 148.0
HKD2_k127_4242031_4 - - - - 0.000000004199 69.0
HKD2_k127_4268886_0 ABC transporter transmembrane region K06147 - - 9.246e-252 790.0
HKD2_k127_4268886_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 343.0
HKD2_k127_4268886_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000001593 214.0
HKD2_k127_4284748_0 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 572.0
HKD2_k127_4284748_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 533.0
HKD2_k127_4284748_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 501.0
HKD2_k127_4284748_3 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 284.0
HKD2_k127_4284748_4 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000002506 142.0
HKD2_k127_4284748_5 Transcription regulator K03718 - - 0.00000000000000000000000000000002432 131.0
HKD2_k127_4287319_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1174.0
HKD2_k127_4287319_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 3.321e-247 771.0
HKD2_k127_4287319_10 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.00000000000000000000000000000003097 130.0
HKD2_k127_4287319_11 sugar transferase K00996 - 2.7.8.6 0.0000000002456 66.0
HKD2_k127_4287319_2 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 544.0
HKD2_k127_4287319_3 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 507.0
HKD2_k127_4287319_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 511.0
HKD2_k127_4287319_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 392.0
HKD2_k127_4287319_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 316.0
HKD2_k127_4287319_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001532 236.0
HKD2_k127_4287319_8 - - - - 0.000000000000000000000000000000000000001245 151.0
HKD2_k127_4287319_9 CobQ CobB MinD ParA nucleotide binding domain - - - 0.0000000000000000000000000000000008654 149.0
HKD2_k127_4294211_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000005781 173.0
HKD2_k127_4294211_1 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000000000000000009402 145.0
HKD2_k127_4294211_2 GyrI-like small molecule binding domain - - - 0.000000000000000000000005805 103.0
HKD2_k127_4294211_3 lysyltransferase activity K07027 - - 0.000000000000000001584 89.0
HKD2_k127_431925_0 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 442.0
HKD2_k127_431925_1 acetyltransferase K03826 - - 0.00000000000000000000000001038 115.0
HKD2_k127_4327994_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 7.242e-291 910.0
HKD2_k127_4327994_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000003578 101.0
HKD2_k127_4327994_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000718 69.0
HKD2_k127_4427433_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 431.0
HKD2_k127_4427433_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 424.0
HKD2_k127_4427433_2 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 396.0
HKD2_k127_4427433_3 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 362.0
HKD2_k127_4427433_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 308.0
HKD2_k127_4427433_5 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000002761 201.0
HKD2_k127_4427433_6 PAS fold - - - 0.000000000000000000000000000000000000000001971 182.0
HKD2_k127_4427433_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000002455 156.0
HKD2_k127_4427433_8 Armadillo/beta-catenin-like repeats - - - 0.000000000000000000000000000000105 139.0
HKD2_k127_444146_0 transmembrane transporter activity K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000009389 246.0
HKD2_k127_444146_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000009867 146.0
HKD2_k127_4458642_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 513.0
HKD2_k127_4458642_1 Periplasmic binding protein domain K10543,K10546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 478.0
HKD2_k127_4458642_2 D-xylose transmembrane transport K10543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 415.0
HKD2_k127_4458642_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 376.0
HKD2_k127_4458642_4 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 318.0
HKD2_k127_4458642_5 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000008086 146.0
HKD2_k127_4458642_6 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000003871 134.0
HKD2_k127_4458642_8 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000002857 130.0
HKD2_k127_4469605_0 PFAM peptidase, membrane zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
HKD2_k127_4469605_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 287.0
HKD2_k127_4469605_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008071 258.0
HKD2_k127_4469605_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000005399 259.0
HKD2_k127_4469605_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001244 235.0
HKD2_k127_4469605_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000001497 128.0
HKD2_k127_4469605_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000002641 103.0
HKD2_k127_4469605_7 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0000000001271 69.0
HKD2_k127_4517680_0 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 396.0
HKD2_k127_4517680_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 353.0
HKD2_k127_4517680_11 PFAM DSBA oxidoreductase - - - 0.000005684 57.0
HKD2_k127_4517680_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03805,K12228 - - 0.000007569 57.0
HKD2_k127_4517680_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003532 260.0
HKD2_k127_4517680_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
HKD2_k127_4517680_4 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000001017 198.0
HKD2_k127_4517680_5 - - - - 0.000000000000000000000000000000000000000001266 164.0
HKD2_k127_4517680_6 - - - - 0.00000000000000000000000000000005338 135.0
HKD2_k127_4517680_7 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000005478 87.0
HKD2_k127_4517680_9 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000001906 80.0
HKD2_k127_4589292_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 3.401e-211 673.0
HKD2_k127_4589292_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 581.0
HKD2_k127_4589292_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 371.0
HKD2_k127_4589292_3 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005165 246.0
HKD2_k127_4589292_4 acyl-coa hydrolase K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000008993 180.0
HKD2_k127_4589292_5 IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000001641 181.0
HKD2_k127_4589292_6 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000001715 121.0
HKD2_k127_4589292_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000003285 75.0
HKD2_k127_4592270_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.886e-298 939.0
HKD2_k127_4592270_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
HKD2_k127_4592270_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000002831 245.0
HKD2_k127_4592270_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001958 192.0
HKD2_k127_4592270_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000021 96.0
HKD2_k127_459239_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.376e-269 839.0
HKD2_k127_459239_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 292.0
HKD2_k127_459239_2 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002672 265.0
HKD2_k127_459239_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000001535 166.0
HKD2_k127_459239_4 Belongs to the Fur family K03711 - - 0.00000000000000000001072 96.0
HKD2_k127_4592647_0 PFAM Dak phosphatase K07030 - - 6.568e-211 669.0
HKD2_k127_4592647_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000001246 229.0
HKD2_k127_4592647_2 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000000000000001209 159.0
HKD2_k127_4592647_3 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000001052 162.0
HKD2_k127_4592647_4 ribosomal protein L28 K02902 - - 0.00000000000000000000004912 100.0
HKD2_k127_459358_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1188.0
HKD2_k127_459358_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 590.0
HKD2_k127_459358_10 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000002072 111.0
HKD2_k127_459358_11 Peptidoglycan-binding domain 1 protein - - - 0.0000000000003996 80.0
HKD2_k127_459358_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 462.0
HKD2_k127_459358_3 diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 403.0
HKD2_k127_459358_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
HKD2_k127_459358_5 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006854 267.0
HKD2_k127_459358_6 dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000004406 187.0
HKD2_k127_459358_7 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000001413 137.0
HKD2_k127_459358_8 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000001297 117.0
HKD2_k127_459358_9 dehydrogenase - - - 0.000000000000000000000000001442 114.0
HKD2_k127_4607512_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 605.0
HKD2_k127_4607512_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 549.0
HKD2_k127_4607512_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 377.0
HKD2_k127_4607512_3 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002337 259.0
HKD2_k127_4607512_4 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000303 189.0
HKD2_k127_4607512_5 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000009152 167.0
HKD2_k127_4607512_6 glyoxalase III activity - - - 0.0000000000000000000000000006425 118.0
HKD2_k127_4607512_7 YCII-related domain - - - 0.000000000000000000000003498 106.0
HKD2_k127_4607512_8 Esterase PHB depolymerase K03932 - - 0.000000000000007984 83.0
HKD2_k127_4619650_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1267.0
HKD2_k127_4619650_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 301.0
HKD2_k127_4619650_2 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 282.0
HKD2_k127_4619650_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001378 228.0
HKD2_k127_4619650_4 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000001857 211.0
HKD2_k127_4619650_5 Inner membrane component domain - - - 0.00000000000000000000000000000000000000000000000000001878 192.0
HKD2_k127_4619650_6 DNA-binding transcription factor activity K15973 - - 0.00000000000000000000000000000000000000000000000000004838 190.0
HKD2_k127_4619650_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000006528 165.0
HKD2_k127_4619650_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000004473 155.0
HKD2_k127_4657453_0 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 419.0
HKD2_k127_4657453_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 321.0
HKD2_k127_4657453_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
HKD2_k127_4657453_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000005535 190.0
HKD2_k127_4657453_4 Regulatory protein, FmdB family - - - 0.0000000000000000000000000008018 115.0
HKD2_k127_4657453_5 YhhN family - - - 0.0000000000004347 78.0
HKD2_k127_4667147_0 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 577.0
HKD2_k127_4667147_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 236.0
HKD2_k127_4719021_0 L-arabinose isomerase activity K01804 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 5.3.1.4 2.53e-234 734.0
HKD2_k127_4719021_1 Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 297.0
HKD2_k127_4719021_2 Cna B domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 320.0
HKD2_k127_4719021_3 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000002209 195.0
HKD2_k127_4719021_4 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 0.00000000000000000805 83.0
HKD2_k127_4846971_0 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 286.0
HKD2_k127_4846971_1 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000008577 205.0
HKD2_k127_4846971_2 Prolyl oligopeptidase family - - - 0.0006485 52.0
HKD2_k127_4859983_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000745 221.0
HKD2_k127_4859983_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000001346 211.0
HKD2_k127_4859983_2 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000001392 154.0
HKD2_k127_4859983_3 acetyltransferase - - - 0.000000001865 59.0
HKD2_k127_4864584_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.881e-200 631.0
HKD2_k127_4864584_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 482.0
HKD2_k127_4864584_11 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000001979 135.0
HKD2_k127_4864584_12 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000002878 94.0
HKD2_k127_4864584_13 Putative zinc-finger - - - 0.000000001757 61.0
HKD2_k127_4864584_15 TPR repeat - - - 0.0003698 55.0
HKD2_k127_4864584_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 439.0
HKD2_k127_4864584_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 411.0
HKD2_k127_4864584_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
HKD2_k127_4864584_5 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000001397 194.0
HKD2_k127_4864584_6 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000000000000000000000003038 179.0
HKD2_k127_4864584_7 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000002235 180.0
HKD2_k127_4864584_8 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000006712 178.0
HKD2_k127_4864584_9 TIGRFAM glutaredoxin-like domain protein - - - 0.00000000000000000000000000000000000001423 148.0
HKD2_k127_4928148_0 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 565.0
HKD2_k127_4928148_1 DNA-binding transcription factor activity - - - 0.0000000000000000003168 92.0
HKD2_k127_4960281_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.661e-237 743.0
HKD2_k127_4960281_1 PFAM Cytochrome C assembly protein K02198 - - 4.334e-236 737.0
HKD2_k127_4960281_10 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000003403 149.0
HKD2_k127_4960281_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000000000008225 148.0
HKD2_k127_4960281_12 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000002156 132.0
HKD2_k127_4960281_13 zinc-ribbon domain - - - 0.0000000000000000000000000003684 120.0
HKD2_k127_4960281_14 Protein of unknown function (DUF1232) - - - 0.0000000000000000000002095 101.0
HKD2_k127_4960281_15 - - - - 0.0000000000006261 70.0
HKD2_k127_4960281_17 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01185,K02395,K19223 - 3.2.1.17 0.000001016 60.0
HKD2_k127_4960281_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 499.0
HKD2_k127_4960281_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 439.0
HKD2_k127_4960281_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 392.0
HKD2_k127_4960281_5 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 328.0
HKD2_k127_4960281_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
HKD2_k127_4960281_7 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD2_k127_4960281_8 PFAM Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 297.0
HKD2_k127_4960281_9 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000001055 201.0
HKD2_k127_4984359_0 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
HKD2_k127_4984359_1 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 317.0
HKD2_k127_4991857_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 514.0
HKD2_k127_4991857_1 Histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 492.0
HKD2_k127_4991857_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001493 207.0
HKD2_k127_4991857_3 Histidine kinase K11617 - 2.7.13.3 0.000000000000000000000000000000000000231 158.0
HKD2_k127_4991857_4 - - - - 0.000000000000000000000000000000000004699 143.0
HKD2_k127_4991857_5 lactoylglutathione lyase activity - - - 0.0000000000000000000002562 97.0
HKD2_k127_5007585_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 510.0
HKD2_k127_5007585_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 338.0
HKD2_k127_5007585_2 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 326.0
HKD2_k127_5013196_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 6.672e-243 760.0
HKD2_k127_5013196_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 513.0
HKD2_k127_5013196_10 PFAM regulatory protein GntR HTH K07979 - - 0.0000000000000000000000000000001545 130.0
HKD2_k127_5013196_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 422.0
HKD2_k127_5013196_3 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 411.0
HKD2_k127_5013196_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
HKD2_k127_5013196_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
HKD2_k127_5013196_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000002072 244.0
HKD2_k127_5013196_7 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000005331 204.0
HKD2_k127_5013196_8 integral membrane protein - - - 0.00000000000000000000000000000000000000000007274 168.0
HKD2_k127_5025628_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 552.0
HKD2_k127_5025628_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001246 272.0
HKD2_k127_5025628_2 Arylsulfatase a K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003268 266.0
HKD2_k127_5025628_3 - - - - 0.000000000000000000000000000000000000000000000000000000000001326 214.0
HKD2_k127_5089786_0 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003942 236.0
HKD2_k127_5089786_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000007313 146.0
HKD2_k127_5089786_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000002315 137.0
HKD2_k127_5089786_3 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000002231 124.0
HKD2_k127_5089786_4 Tetratricopeptide repeat - - - 0.0007335 51.0
HKD2_k127_5089811_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 594.0
HKD2_k127_5089811_1 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 457.0
HKD2_k127_5089811_2 4Fe-4S binding domain K14091 - - 0.0000000000000000000000000000000000000000001282 160.0
HKD2_k127_5089811_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.0000000000000000000000000000000000000000067 156.0
HKD2_k127_5089811_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332,K13378 - 1.6.5.3 0.00000000000000000000000000000000008231 140.0
HKD2_k127_5106617_0 Peptidase family C69 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 475.0
HKD2_k127_5106617_1 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 327.0
HKD2_k127_5106617_2 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000000000000000000000000000000000000000002566 226.0
HKD2_k127_5106617_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000003119 156.0
HKD2_k127_5123556_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 1.182e-310 972.0
HKD2_k127_5123556_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.207e-212 664.0
HKD2_k127_5123556_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.343e-208 653.0
HKD2_k127_5123556_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004279 258.0
HKD2_k127_5123556_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002282 203.0
HKD2_k127_5123556_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000003824 131.0
HKD2_k127_5189393_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.692e-267 831.0
HKD2_k127_5189393_1 metal-dependent phosphohydrolase, HD sub domain K07037 - - 4.457e-196 633.0
HKD2_k127_5189393_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000001597 66.0
HKD2_k127_5189393_2 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 522.0
HKD2_k127_5189393_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 349.0
HKD2_k127_5189393_4 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 346.0
HKD2_k127_5189393_5 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000006729 160.0
HKD2_k127_5189393_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000004592 150.0
HKD2_k127_5189393_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000008855 124.0
HKD2_k127_5189393_8 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.00000000000000000000000000002035 119.0
HKD2_k127_5189393_9 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000003547 120.0
HKD2_k127_5190797_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 538.0
HKD2_k127_5190797_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 497.0
HKD2_k127_5190797_2 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 359.0
HKD2_k127_5190797_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
HKD2_k127_5190797_4 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
HKD2_k127_5190797_5 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
HKD2_k127_5190797_6 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000001163 69.0
HKD2_k127_5205945_0 PFAM Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002324 281.0
HKD2_k127_5205945_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 270.0
HKD2_k127_5205945_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005023 270.0
HKD2_k127_5205945_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001581 254.0
HKD2_k127_5205945_4 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000002629 174.0
HKD2_k127_5205945_5 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000001804 179.0
HKD2_k127_5205945_6 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000003243 138.0
HKD2_k127_5294262_0 lipid binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
HKD2_k127_5294262_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001759 263.0
HKD2_k127_5294262_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K18917 - 1.20.4.3 0.0000000000000000002049 92.0
HKD2_k127_5294262_3 Protein of unknown function (DUF3105) - - - 0.00000001949 63.0
HKD2_k127_5294262_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000005956 57.0
HKD2_k127_5296239_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000003191 234.0
HKD2_k127_5296239_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002987 220.0
HKD2_k127_5296239_2 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000005393 193.0
HKD2_k127_5296239_3 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.0000000000000000000000000000000000000000000000001514 188.0
HKD2_k127_5296239_4 Flagellar motor protein K02557 - - 0.000000000000000000000000000000000000003728 156.0
HKD2_k127_5296239_5 PFAM flagellar FlbD family protein K02385 - - 0.000000000005866 69.0
HKD2_k127_5296239_6 transferase activity, transferring glycosyl groups K20444 - - 0.000000005593 69.0
HKD2_k127_5316114_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 608.0
HKD2_k127_5316114_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 490.0
HKD2_k127_5316114_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 383.0
HKD2_k127_5316114_3 - K14340 - - 0.00000000000000000000000000000000000000000000000009811 199.0
HKD2_k127_5316114_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000001693 171.0
HKD2_k127_5316114_5 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.0000000000000000000000000000000000004148 149.0
HKD2_k127_5316114_6 Rdx family K07401 - - 0.00000000000001956 74.0
HKD2_k127_5316114_7 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000005132 78.0
HKD2_k127_5323098_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 381.0
HKD2_k127_5323098_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000005589 149.0
HKD2_k127_5323098_2 peroxiredoxin activity - - - 0.00000000000000000000000004059 115.0
HKD2_k127_5323098_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000625 116.0
HKD2_k127_5323098_4 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000000000003853 94.0
HKD2_k127_5351773_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 344.0
HKD2_k127_5351773_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 308.0
HKD2_k127_5351773_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
HKD2_k127_5364098_0 PFAM peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 578.0
HKD2_k127_5364098_1 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 304.0
HKD2_k127_5364098_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000004242 210.0
HKD2_k127_5364098_3 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01185,K02395,K19223 - 3.2.1.17 0.00002656 46.0
HKD2_k127_5400142_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 432.0
HKD2_k127_5400142_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 290.0
HKD2_k127_5400142_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000002544 236.0
HKD2_k127_5400142_3 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000003305 162.0
HKD2_k127_5400142_4 Metal-sensitive transcriptional repressor K21600 - - 0.000000001551 61.0
HKD2_k127_5400142_5 - - - - 0.00000007631 61.0
HKD2_k127_5400354_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002187 277.0
HKD2_k127_5400354_1 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000000000000000002837 240.0
HKD2_k127_5400354_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000009885 244.0
HKD2_k127_5400354_3 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000001615 169.0
HKD2_k127_5400354_4 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000004262 83.0
HKD2_k127_5400354_5 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000001951 68.0
HKD2_k127_5432812_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 447.0
HKD2_k127_5432812_1 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 351.0
HKD2_k127_5432812_2 COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
HKD2_k127_5432812_3 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001612 246.0
HKD2_k127_5432812_4 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000000000005481 181.0
HKD2_k127_544558_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 501.0
HKD2_k127_544558_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 493.0
HKD2_k127_544558_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 432.0
HKD2_k127_544558_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008715 255.0
HKD2_k127_544558_4 - - - - 0.000000000000000000000000000000000000132 148.0
HKD2_k127_544558_5 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000001393 141.0
HKD2_k127_544558_6 RDD family - - - 0.000000000000000000000000006454 117.0
HKD2_k127_544558_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000008185 89.0
HKD2_k127_5461163_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 0.0 1028.0
HKD2_k127_5461163_1 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000006329 145.0
HKD2_k127_5471499_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 445.0
HKD2_k127_5471499_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 424.0
HKD2_k127_5471499_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 314.0
HKD2_k127_5471499_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000001178 173.0
HKD2_k127_5587094_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.296e-288 893.0
HKD2_k127_5587094_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 524.0
HKD2_k127_5587094_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 493.0
HKD2_k127_5587094_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 419.0
HKD2_k127_5587094_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 398.0
HKD2_k127_5587094_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
HKD2_k127_5587094_6 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 351.0
HKD2_k127_5587094_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000001722 161.0
HKD2_k127_5587094_8 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000009668 119.0
HKD2_k127_5587094_9 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000001217 89.0
HKD2_k127_5591220_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 5.27e-224 706.0
HKD2_k127_5591220_1 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 538.0
HKD2_k127_5591220_2 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 523.0
HKD2_k127_5591220_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 515.0
HKD2_k127_5591220_4 Molybdopterin dehydrogenase K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000717 192.0
HKD2_k127_5613842_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 569.0
HKD2_k127_5613842_1 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 387.0
HKD2_k127_5613842_2 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003734 277.0
HKD2_k127_5613842_3 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000001543 233.0
HKD2_k127_5613842_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000009616 195.0
HKD2_k127_5613842_6 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000159 106.0
HKD2_k127_5624643_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 6.734e-289 901.0
HKD2_k127_5624643_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 561.0
HKD2_k127_5624643_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 277.0
HKD2_k127_5624643_3 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000001813 130.0
HKD2_k127_5624643_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000008824 120.0
HKD2_k127_5681957_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 604.0
HKD2_k127_5681957_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 600.0
HKD2_k127_5681957_10 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000003139 165.0
HKD2_k127_5681957_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 543.0
HKD2_k127_5681957_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 485.0
HKD2_k127_5681957_4 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 446.0
HKD2_k127_5681957_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 439.0
HKD2_k127_5681957_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 425.0
HKD2_k127_5681957_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 398.0
HKD2_k127_5681957_8 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000001916 224.0
HKD2_k127_5682150_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 9.809e-232 724.0
HKD2_k127_5682150_1 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 330.0
HKD2_k127_5682150_2 PFAM membrane-flanked domain - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
HKD2_k127_5682150_3 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000007132 164.0
HKD2_k127_5682150_5 ABC transporter transmembrane region K06147 - - 0.00000009246 55.0
HKD2_k127_5699080_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1089.0
HKD2_k127_5699080_1 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 465.0
HKD2_k127_5699080_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 268.0
HKD2_k127_5699080_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000002493 171.0
HKD2_k127_5741448_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1293.0
HKD2_k127_5741448_1 auxin-activated signaling pathway K07088 - - 0.00000000000000000000000000000000000000000000000001342 191.0
HKD2_k127_5741448_2 redox protein regulator of disulfide bond formation - - - 0.0002039 47.0
HKD2_k127_5759946_0 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 452.0
HKD2_k127_5759946_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 417.0
HKD2_k127_5759946_10 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001593 226.0
HKD2_k127_5759946_11 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000008956 166.0
HKD2_k127_5759946_12 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000002894 163.0
HKD2_k127_5759946_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000002788 143.0
HKD2_k127_5759946_14 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000001584 138.0
HKD2_k127_5759946_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 368.0
HKD2_k127_5759946_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
HKD2_k127_5759946_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 318.0
HKD2_k127_5759946_5 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
HKD2_k127_5759946_6 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 291.0
HKD2_k127_5759946_7 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008668 277.0
HKD2_k127_5759946_8 nucleoside-diphosphate sugar epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 271.0
HKD2_k127_5759946_9 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001804 258.0
HKD2_k127_5783336_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 343.0
HKD2_k127_5783336_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000002816 221.0
HKD2_k127_5783336_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000006531 151.0
HKD2_k127_5801387_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 434.0
HKD2_k127_5801387_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 421.0
HKD2_k127_5801387_2 ABC-3 protein K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 342.0
HKD2_k127_5801387_3 PFAM ABC transporter related K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000424 281.0
HKD2_k127_5801387_4 Belongs to the bacterial solute-binding protein 9 family K02077,K09818 - - 0.000000000000000000000000000000000003242 140.0
HKD2_k127_5801387_5 phosphatase (DUF442) - - - 0.0000000000000000000000000000000001954 138.0
HKD2_k127_5801387_6 maltose binding K02027,K15770 - - 0.000000000000000000000000000001373 136.0
HKD2_k127_5801387_7 lipoprotein biosynthetic process K13292 - - 0.0003012 52.0
HKD2_k127_5832322_0 PFAM natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 582.0
HKD2_k127_5832322_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 527.0
HKD2_k127_5832322_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 374.0
HKD2_k127_5832322_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 353.0
HKD2_k127_5832322_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001251 252.0
HKD2_k127_5832322_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
HKD2_k127_5832322_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002895 207.0
HKD2_k127_5832322_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001245 199.0
HKD2_k127_5832322_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000001704 188.0
HKD2_k127_5839392_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 1.109e-271 850.0
HKD2_k127_5839392_1 TIGRFAM MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 330.0
HKD2_k127_5839392_10 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000001695 81.0
HKD2_k127_5839392_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001919 74.0
HKD2_k127_5839392_13 Tetratricopeptide repeat - - - 0.000007653 50.0
HKD2_k127_5839392_2 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 297.0
HKD2_k127_5839392_3 TrkA-N domain K03499,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001618 256.0
HKD2_k127_5839392_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004233 256.0
HKD2_k127_5839392_5 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000000000000000000000000001692 186.0
HKD2_k127_5839392_6 amino acid activation for nonribosomal peptide biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000124 190.0
HKD2_k127_5839392_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000000000000001274 163.0
HKD2_k127_5839392_9 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002354 96.0
HKD2_k127_5923870_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.309e-222 703.0
HKD2_k127_5923870_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 500.0
HKD2_k127_5923870_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 458.0
HKD2_k127_5923870_3 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 457.0
HKD2_k127_5923870_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 387.0
HKD2_k127_5964125_0 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 299.0
HKD2_k127_5964125_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
HKD2_k127_5964125_2 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
HKD2_k127_5964125_3 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000008401 224.0
HKD2_k127_5964125_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000003496 148.0
HKD2_k127_5964125_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000002358 145.0
HKD2_k127_5964125_6 Ribosomal L27 protein K02899 - - 0.00000000000000000000000000000000007546 135.0
HKD2_k127_5998150_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 7.757e-202 635.0
HKD2_k127_5998150_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 461.0
HKD2_k127_5998150_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000000341 166.0
HKD2_k127_5998150_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000008349 136.0
HKD2_k127_5998150_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000001881 132.0
HKD2_k127_6137875_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1094.0
HKD2_k127_6137875_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001048 286.0
HKD2_k127_6137875_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000007174 238.0
HKD2_k127_623380_0 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 422.0
HKD2_k127_623380_1 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 364.0
HKD2_k127_623380_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000001533 240.0
HKD2_k127_623380_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000002098 208.0
HKD2_k127_623380_4 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000003438 171.0
HKD2_k127_623380_5 PhoQ Sensor K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000004038 134.0
HKD2_k127_623380_6 Phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000006075 130.0
HKD2_k127_623380_7 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000005949 81.0
HKD2_k127_623380_8 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000000002408 67.0
HKD2_k127_6237469_0 PFAM type II secretion system protein E K02283 - - 6.276e-200 631.0
HKD2_k127_6237469_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 364.0
HKD2_k127_6237469_10 GAF domain - - - 0.00000000000000000000000000000000000000000000000000004871 199.0
HKD2_k127_6237469_11 Helix-turn-helix domain K07219 - - 0.0000000000000000000000000000000000000000000002165 181.0
HKD2_k127_6237469_12 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000342 172.0
HKD2_k127_6237469_13 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000008229 149.0
HKD2_k127_6237469_14 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000009569 135.0
HKD2_k127_6237469_15 - - - - 0.000000000000000000000000005795 113.0
HKD2_k127_6237469_16 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.00000000000001408 74.0
HKD2_k127_6237469_17 Transcriptional regulator K07979 - - 0.0000001659 63.0
HKD2_k127_6237469_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 355.0
HKD2_k127_6237469_3 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 350.0
HKD2_k127_6237469_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 306.0
HKD2_k127_6237469_5 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 306.0
HKD2_k127_6237469_6 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 293.0
HKD2_k127_6237469_7 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 288.0
HKD2_k127_6237469_8 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000002185 236.0
HKD2_k127_6237469_9 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000000000000000000000000000002132 218.0
HKD2_k127_6249250_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 3.55e-201 642.0
HKD2_k127_6249250_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.206e-198 632.0
HKD2_k127_6249250_10 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000133 173.0
HKD2_k127_6249250_11 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000001379 160.0
HKD2_k127_6249250_12 Virulence activator alpha C-term - - - 0.000000000000000000000000000000000000005265 152.0
HKD2_k127_6249250_13 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000006874 147.0
HKD2_k127_6249250_14 chromate transporter K07240 - - 0.00000000000000000000000000000005534 130.0
HKD2_k127_6249250_15 Protein of unknown function (DUF454) K09790 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000001316 114.0
HKD2_k127_6249250_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000008439 103.0
HKD2_k127_6249250_17 - - - - 0.000000000000000000127 93.0
HKD2_k127_6249250_18 - - - - 0.000000001674 60.0
HKD2_k127_6249250_2 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 411.0
HKD2_k127_6249250_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 382.0
HKD2_k127_6249250_4 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 298.0
HKD2_k127_6249250_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
HKD2_k127_6249250_6 Nitroreductase family K19285 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000008292 256.0
HKD2_k127_6249250_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000001333 209.0
HKD2_k127_6249250_8 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001876 230.0
HKD2_k127_6249250_9 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000003233 205.0
HKD2_k127_6401623_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 8.871e-194 607.0
HKD2_k127_6401623_1 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 596.0
HKD2_k127_6401623_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000002342 186.0
HKD2_k127_6401623_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000001198 140.0
HKD2_k127_6401623_12 Haem-binding domain - - - 0.00000000000000000000000000000007367 130.0
HKD2_k127_6401623_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000001734 89.0
HKD2_k127_6401623_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 567.0
HKD2_k127_6401623_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 560.0
HKD2_k127_6401623_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 491.0
HKD2_k127_6401623_5 ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD K16013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 426.0
HKD2_k127_6401623_6 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 390.0
HKD2_k127_6401623_7 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012,K16014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 321.0
HKD2_k127_6401623_8 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007321 251.0
HKD2_k127_6401623_9 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001623 245.0
HKD2_k127_6500523_0 Belongs to the peptidase S41A family - - - 1.056e-238 764.0
HKD2_k127_6500523_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000003662 154.0
HKD2_k127_6500523_2 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000122 59.0
HKD2_k127_6529205_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 3.425e-202 637.0
HKD2_k127_6529205_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 395.0
HKD2_k127_6529205_2 PFAM DegV family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
HKD2_k127_6529205_3 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001153 155.0
HKD2_k127_6529205_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000002776 156.0
HKD2_k127_6529205_5 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000009257 120.0
HKD2_k127_6529205_6 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000007601 102.0
HKD2_k127_6560715_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.058e-262 820.0
HKD2_k127_6560715_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 387.0
HKD2_k127_6560715_10 copper radical oxidase K20929 - 1.2.3.15 0.0008479 53.0
HKD2_k127_6560715_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006903 277.0
HKD2_k127_6560715_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009931 281.0
HKD2_k127_6560715_4 SPTR Hemolysin-type calcium-binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000228 240.0
HKD2_k127_6560715_5 SPTR Hemolysin-type calcium-binding region - - - 0.0000000000000000000000000000000000000000000000000001422 211.0
HKD2_k127_6560715_6 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000002097 190.0
HKD2_k127_6560715_7 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000001607 130.0
HKD2_k127_6560715_8 Methyltransferase domain - - - 0.000000002673 68.0
HKD2_k127_6577348_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 460.0
HKD2_k127_6577348_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
HKD2_k127_6577348_2 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000001576 251.0
HKD2_k127_6577348_3 Chemotaxis protein CheY K03413 - - 0.0000000000000000000000000000000000000000002818 160.0
HKD2_k127_6577348_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000004981 121.0
HKD2_k127_6577348_5 Chemotaxis protein CheC K03410 - - 0.00000000000000000000000001248 117.0
HKD2_k127_6577348_6 Peptidase, M23 - - - 0.000000000000000000000001254 114.0
HKD2_k127_6577348_7 PFAM HDOD domain - - - 0.000000000006383 68.0
HKD2_k127_6580950_0 RibD C-terminal domain K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000002083 224.0
HKD2_k127_6580950_1 HAD-hyrolase-like K19270 - 3.1.3.23 0.00000000000000000000000000000000000000000000000000000000001169 214.0
HKD2_k127_6580950_10 TfoX N-terminal domain - - - 0.0000000000000000000004263 100.0
HKD2_k127_6580950_12 - - - - 0.0000000000009499 70.0
HKD2_k127_6580950_2 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000001449 193.0
HKD2_k127_6580950_3 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000000000000000000000000000000000000000000001108 177.0
HKD2_k127_6580950_4 Acetyltransferase - - - 0.0000000000000000000000000000000000000000002609 161.0
HKD2_k127_6580950_5 Pkd domain containing protein - - - 0.0000000000000000000000000000000000001449 151.0
HKD2_k127_6580950_6 - - - - 0.000000000000000000000000000000000009149 139.0
HKD2_k127_6580950_7 - - - - 0.0000000000000000000000000001357 119.0
HKD2_k127_6580950_8 Domain of unknown function (DU1801) - - - 0.000000000000000000000000006383 113.0
HKD2_k127_6644826_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1168.0
HKD2_k127_6644826_1 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 1.397e-239 760.0
HKD2_k127_6644826_2 solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 585.0
HKD2_k127_6644826_3 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 388.0
HKD2_k127_6644826_4 PFAM Binding-protein-dependent transport system inner membrane component K02026,K10242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 338.0
HKD2_k127_6644826_5 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 336.0
HKD2_k127_6644826_6 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 297.0
HKD2_k127_6644826_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005477 276.0
HKD2_k127_6644826_8 Patatin-like phospholipase K07001 - - 0.000000000000005737 79.0
HKD2_k127_6699025_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 366.0
HKD2_k127_6699025_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 366.0
HKD2_k127_6699025_2 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000004927 112.0
HKD2_k127_6699025_3 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000006239 99.0
HKD2_k127_6699025_4 Tetratricopeptide repeat - - - 0.00000000329 69.0
HKD2_k127_6699210_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 306.0
HKD2_k127_6699210_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000009871 245.0
HKD2_k127_6699210_2 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000121 212.0
HKD2_k127_6699210_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000002539 179.0
HKD2_k127_6699210_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000000001371 121.0
HKD2_k127_6699210_5 - - - - 0.000000000000000000000004235 108.0
HKD2_k127_6699210_6 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000006789 96.0
HKD2_k127_6703122_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1085.0
HKD2_k127_6703122_1 Aminotransferase class-V - - - 6.062e-196 621.0
HKD2_k127_6703122_10 AraC-like ligand binding domain - - - 0.0000000000000000000000000000001253 127.0
HKD2_k127_6703122_11 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000001454 111.0
HKD2_k127_6703122_2 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 484.0
HKD2_k127_6703122_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 459.0
HKD2_k127_6703122_4 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 373.0
HKD2_k127_6703122_5 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 338.0
HKD2_k127_6703122_6 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 301.0
HKD2_k127_6703122_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
HKD2_k127_6703122_8 HD domain K21138 GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006163,GO:0006195,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008893,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009154,GO:0009164,GO:0009166,GO:0009259,GO:0009261,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0015971,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0031667,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034035,GO:0034037,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.7.2 0.0000000000000000000000000000000000000000000000000001241 191.0
HKD2_k127_6703122_9 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000000000000004171 179.0
HKD2_k127_6703380_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
HKD2_k127_6703380_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 349.0
HKD2_k127_6703380_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000003178 224.0
HKD2_k127_6703380_3 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000004459 199.0
HKD2_k127_6703380_4 - - - - 0.00000000000000000000000000000000000000000000000003664 190.0
HKD2_k127_6703380_5 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000000000000000008973 178.0
HKD2_k127_6703380_6 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000001318 158.0
HKD2_k127_6703380_7 - - - - 0.000000000000000000000000000000000000000001732 164.0
HKD2_k127_6703380_8 DinB family - - - 0.000000000000002537 82.0
HKD2_k127_6703380_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000004479 74.0
HKD2_k127_6718429_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 373.0
HKD2_k127_6718429_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 334.0
HKD2_k127_6718429_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 332.0
HKD2_k127_6718429_3 - - - - 0.000000000000000000000000000000000001389 147.0
HKD2_k127_6718429_4 Domain of unknown function (DUF4180) - - - 0.00000000000000000000000003384 111.0
HKD2_k127_6718429_5 PFAM regulatory protein TetR K09017 - - 0.0000000000000000007128 94.0
HKD2_k127_6748206_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 470.0
HKD2_k127_6748206_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 445.0
HKD2_k127_6748206_10 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000003194 123.0
HKD2_k127_6748206_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000002607 118.0
HKD2_k127_6748206_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 403.0
HKD2_k127_6748206_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 411.0
HKD2_k127_6748206_4 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002588 265.0
HKD2_k127_6748206_5 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000001502 236.0
HKD2_k127_6748206_6 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000006031 189.0
HKD2_k127_6748206_7 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000001437 132.0
HKD2_k127_6748206_8 - - - - 0.000000000000000000000000000000006798 132.0
HKD2_k127_6748206_9 iron-sulfur cluster assembly - - - 0.00000000000000000000000000001312 120.0
HKD2_k127_6806988_0 Alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 384.0
HKD2_k127_6806988_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
HKD2_k127_6806988_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000366 208.0
HKD2_k127_6806988_3 Domain of unknown function (DUF4342) - - - 0.000000000000000000000613 97.0
HKD2_k127_6806988_4 serine-type peptidase activity - - - 0.000000006834 68.0
HKD2_k127_6820961_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 553.0
HKD2_k127_6820961_1 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 316.0
HKD2_k127_6820961_2 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005863 270.0
HKD2_k127_6820961_3 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000000001388 216.0
HKD2_k127_6820961_4 membrane - - - 0.00000000000000000000000000000000000000000000000000007212 198.0
HKD2_k127_6820961_5 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000002748 191.0
HKD2_k127_6820961_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000004243 184.0
HKD2_k127_6820961_7 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000007764 151.0
HKD2_k127_6820961_8 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000392 126.0
HKD2_k127_6820961_9 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000003609 123.0
HKD2_k127_684805_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.159e-298 930.0
HKD2_k127_684805_1 PFAM fumarate lyase K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 486.0
HKD2_k127_684805_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 481.0
HKD2_k127_6855108_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006165 276.0
HKD2_k127_6855108_1 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000000000002672 111.0
HKD2_k127_6855108_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000009904 81.0
HKD2_k127_6855108_3 Ankyrin repeat K06867 - - 0.0000000000000003262 81.0
HKD2_k127_6855108_4 Psort location CytoplasmicMembrane, score - - - 0.0001486 54.0
HKD2_k127_6878160_0 polysaccharide deacetylase K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 322.0
HKD2_k127_6878160_1 PhoQ Sensor - - - 0.00000000000000000000000001417 121.0
HKD2_k127_687978_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.586e-293 920.0
HKD2_k127_687978_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.258e-272 861.0
HKD2_k127_687978_10 PFAM DegV family protein - - - 0.0000004084 53.0
HKD2_k127_687978_2 Elongator protein 3, MiaB family, Radical SAM - - - 3.308e-272 850.0
HKD2_k127_687978_3 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 496.0
HKD2_k127_687978_4 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001917 278.0
HKD2_k127_687978_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
HKD2_k127_687978_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000007795 226.0
HKD2_k127_687978_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
HKD2_k127_687978_8 Radical SAM-linked protein - - - 0.00000000000000000000001332 108.0
HKD2_k127_687978_9 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000001109 98.0
HKD2_k127_6881703_0 Stage II sporulation E family protein - - - 2.733e-267 857.0
HKD2_k127_6881703_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005677 258.0
HKD2_k127_6881703_2 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00001308 52.0
HKD2_k127_6969764_0 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 349.0
HKD2_k127_6969764_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
HKD2_k127_6969764_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 308.0
HKD2_k127_6969764_4 cheY-homologous receiver domain - - - 0.00000000000000000000000009426 112.0
HKD2_k127_7015876_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1597.0
HKD2_k127_7015876_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 8.002e-317 990.0
HKD2_k127_7015876_10 competence protein COMEC K02238 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001085 139.0
HKD2_k127_7015876_11 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000009546 132.0
HKD2_k127_7015876_13 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000001362 89.0
HKD2_k127_7015876_14 PspC domain - - - 0.00000000000001689 74.0
HKD2_k127_7015876_15 YacP-like NYN domain K06962 - - 0.0000000001512 68.0
HKD2_k127_7015876_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 528.0
HKD2_k127_7015876_3 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 450.0
HKD2_k127_7015876_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 438.0
HKD2_k127_7015876_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 339.0
HKD2_k127_7015876_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003753 280.0
HKD2_k127_7015876_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000007647 234.0
HKD2_k127_7015876_8 - - - - 0.0000000000000000000000000000000000000001367 158.0
HKD2_k127_7015876_9 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000008427 151.0
HKD2_k127_7050752_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 505.0
HKD2_k127_7050752_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000023 248.0
HKD2_k127_7050752_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000261 205.0
HKD2_k127_7080196_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
HKD2_k127_7080196_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000495 235.0
HKD2_k127_7080196_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000003597 214.0
HKD2_k127_7080196_3 COGs COG2230 Cyclopropane fatty acid synthase and related methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002943 201.0
HKD2_k127_7100298_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K01487,K12960 - 3.5.4.28,3.5.4.3,3.5.4.31 9.096e-207 651.0
HKD2_k127_7100298_1 Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system K02056,K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 580.0
HKD2_k127_7100298_2 transport system permease K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 443.0
HKD2_k127_7100298_3 ABC-type sugar transport system periplasmic component K10439,K17213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 413.0
HKD2_k127_7100298_4 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000008449 163.0
HKD2_k127_7100298_5 all-trans-retinol 13,14-reductase activity - - - 0.0000000000000000000000000000000000000000003892 162.0
HKD2_k127_7100298_6 - - - - 0.00000000000000000000000000005852 122.0
HKD2_k127_7100298_7 Aldo/keto reductase family - - - 0.00000000000000000007219 89.0
HKD2_k127_7100298_8 - K09712,K14475 - - 0.0000000000000008793 80.0
HKD2_k127_7198367_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 309.0
HKD2_k127_7198367_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 255.0
HKD2_k127_7198367_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000001527 183.0
HKD2_k127_7198367_4 - - - - 0.0000000000000000000000000000000000000000000003401 174.0
HKD2_k127_7215343_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1644.0
HKD2_k127_7215343_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.684e-203 658.0
HKD2_k127_7215343_10 cellulase activity - - - 0.00000002885 64.0
HKD2_k127_7215343_2 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 494.0
HKD2_k127_7215343_3 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 468.0
HKD2_k127_7215343_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 366.0
HKD2_k127_7215343_5 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 354.0
HKD2_k127_7215343_6 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 327.0
HKD2_k127_7215343_7 acetyltransferase K06889,K19273 - - 0.0000000000000000000000000000000000000000000283 166.0
HKD2_k127_7215343_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000481 160.0
HKD2_k127_7215343_9 - - - - 0.0000000000000000000000000000000000002434 149.0
HKD2_k127_7217338_0 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 328.0
HKD2_k127_7217338_1 COG0406 Fructose-2,6-bisphosphatase - - - 0.0000000000000000000000000000000000002309 149.0
HKD2_k127_7217338_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000005729 126.0
HKD2_k127_7217338_3 response regulator receiver K03413 - - 0.0000000000000000003989 92.0
HKD2_k127_7217338_4 cellulase activity - - - 0.00000000001019 73.0
HKD2_k127_7307534_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 524.0
HKD2_k127_7307534_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 506.0
HKD2_k127_7307534_2 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
HKD2_k127_7307534_3 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 405.0
HKD2_k127_7307534_4 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 375.0
HKD2_k127_7307534_5 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 347.0
HKD2_k127_7307534_6 Periplasmic binding protein-like domain K10439,K10549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001132 269.0
HKD2_k127_7307534_7 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10441,K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000102 175.0
HKD2_k127_7307534_8 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000197 123.0
HKD2_k127_7318829_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 2.385e-226 714.0
HKD2_k127_7318829_1 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 615.0
HKD2_k127_7318829_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 445.0
HKD2_k127_7318829_3 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 445.0
HKD2_k127_7318829_4 Subtilase family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008396 273.0
HKD2_k127_7349536_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 361.0
HKD2_k127_7349536_1 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004044 285.0
HKD2_k127_7349536_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000001968 228.0
HKD2_k127_7349536_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000002598 217.0
HKD2_k127_7349536_4 Protein of unknown function, DUF488 - - - 0.000000000000000007554 85.0
HKD2_k127_7356330_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 292.0
HKD2_k127_7356330_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000002296 118.0
HKD2_k127_7356330_2 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000007642 95.0
HKD2_k127_7385804_0 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 1.354e-213 670.0
HKD2_k127_7385804_1 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 406.0
HKD2_k127_7385804_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000823 206.0
HKD2_k127_7385804_11 Domain of unknown function (DUF309) K09763 - - 0.000000000000002609 80.0
HKD2_k127_7385804_12 PFAM Propeptide, PepSY amd peptidase M4 - - - 0.000000001146 69.0
HKD2_k127_7385804_14 Sporulation and spore germination - - - 0.0005476 51.0
HKD2_k127_7385804_2 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 379.0
HKD2_k127_7385804_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 356.0
HKD2_k127_7385804_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
HKD2_k127_7385804_5 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
HKD2_k127_7385804_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 322.0
HKD2_k127_7385804_7 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 304.0
HKD2_k127_7385804_8 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
HKD2_k127_7385804_9 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000001231 203.0
HKD2_k127_7388885_0 Heat shock 70 kDa protein K04043 - - 2.073e-286 891.0
HKD2_k127_7388885_1 secreted protein - - - 1.22e-201 647.0
HKD2_k127_7388885_2 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 437.0
HKD2_k127_7388885_3 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 407.0
HKD2_k127_7388885_4 AAA-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008061 262.0
HKD2_k127_7388885_5 uridine phosphorylase activity K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
HKD2_k127_7388885_6 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000005506 231.0
HKD2_k127_7388885_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000002093 132.0
HKD2_k127_7388885_8 photosynthesis - - - 0.00000000008168 72.0
HKD2_k127_7415282_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.021e-313 971.0
HKD2_k127_7415282_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 2.905e-304 959.0
HKD2_k127_7415282_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000212 184.0
HKD2_k127_7415282_3 mercury ion transmembrane transporter activity K07213 - - 0.000000000000003992 76.0
HKD2_k127_7424462_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 411.0
HKD2_k127_7424462_1 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
HKD2_k127_7424462_2 Cysteine-rich secretory protein family - - - 0.000000000000000000001132 106.0
HKD2_k127_7424462_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000006538 83.0
HKD2_k127_7424462_4 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 0.0000000000001293 75.0
HKD2_k127_7424462_5 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000001753 64.0
HKD2_k127_7443920_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1042.0
HKD2_k127_7443920_1 - - - - 0.0000000000000000000000000008708 116.0
HKD2_k127_7516001_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.348e-221 695.0
HKD2_k127_7516001_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.69e-217 681.0
HKD2_k127_7516001_10 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000000000000002132 186.0
HKD2_k127_7516001_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000004432 151.0
HKD2_k127_7516001_13 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000000007299 136.0
HKD2_k127_7516001_14 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.0000000000000000000000000000000001174 142.0
HKD2_k127_7516001_15 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.0000000000000000000001511 101.0
HKD2_k127_7516001_16 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000001174 74.0
HKD2_k127_7516001_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 550.0
HKD2_k127_7516001_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 503.0
HKD2_k127_7516001_4 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
HKD2_k127_7516001_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 424.0
HKD2_k127_7516001_6 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 407.0
HKD2_k127_7516001_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 398.0
HKD2_k127_7516001_8 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 348.0
HKD2_k127_7516001_9 PFAM Stage II sporulation E family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 308.0
HKD2_k127_7524132_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.484e-194 614.0
HKD2_k127_7524132_1 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
HKD2_k127_7524132_2 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
HKD2_k127_7524132_3 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 320.0
HKD2_k127_7524132_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001254 256.0
HKD2_k127_7524132_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000005066 91.0
HKD2_k127_7529985_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 1.924e-260 807.0
HKD2_k127_7529985_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 586.0
HKD2_k127_7529985_11 PFAM Rieske 2Fe-2S domain protein K00363,K05710 - 1.7.1.15 0.000000000000000000000000000008646 123.0
HKD2_k127_7529985_12 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000002882 96.0
HKD2_k127_7529985_13 Pfam:DUF59 - - - 0.000000000000000000001097 99.0
HKD2_k127_7529985_14 SCP-2 sterol transfer family - - - 0.000000000000005443 78.0
HKD2_k127_7529985_15 FeoA domain K04758 - - 0.000005798 51.0
HKD2_k127_7529985_2 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 511.0
HKD2_k127_7529985_3 TIGRFAM FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 493.0
HKD2_k127_7529985_4 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 405.0
HKD2_k127_7529985_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 400.0
HKD2_k127_7529985_6 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 297.0
HKD2_k127_7529985_7 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 256.0
HKD2_k127_7529985_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
HKD2_k127_7529985_9 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000003246 196.0
HKD2_k127_7561017_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 6.183e-246 767.0
HKD2_k127_7561017_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 503.0
HKD2_k127_7561017_2 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 425.0
HKD2_k127_7561017_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 302.0
HKD2_k127_7561017_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003218 274.0
HKD2_k127_7561017_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000002531 181.0
HKD2_k127_7561017_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000003952 169.0
HKD2_k127_7561017_7 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000001341 141.0
HKD2_k127_7561017_9 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000001111 88.0
HKD2_k127_7626844_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 504.0
HKD2_k127_7626844_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 317.0
HKD2_k127_7626844_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000001057 245.0
HKD2_k127_7626844_4 Alpha amylase, catalytic domain - - - 0.000000006066 68.0
HKD2_k127_7633564_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.696e-320 989.0
HKD2_k127_7633564_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 3.856e-301 936.0
HKD2_k127_7633564_10 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002117 220.0
HKD2_k127_7633564_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000002607 209.0
HKD2_k127_7633564_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000008879 179.0
HKD2_k127_7633564_13 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000001071 85.0
HKD2_k127_7633564_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 2.879e-217 684.0
HKD2_k127_7633564_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 468.0
HKD2_k127_7633564_4 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 392.0
HKD2_k127_7633564_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 331.0
HKD2_k127_7633564_6 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 324.0
HKD2_k127_7633564_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 313.0
HKD2_k127_7633564_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004659 218.0
HKD2_k127_7641917_0 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 541.0
HKD2_k127_7641917_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 524.0
HKD2_k127_7641917_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 306.0
HKD2_k127_7641917_3 PFAM Haloacid dehalogenase domain protein hydrolase K07025,K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000000003384 214.0
HKD2_k127_7645431_0 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 2.76e-205 655.0
HKD2_k127_7645431_1 PFAM binding-protein-dependent transport systems inner membrane component K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 353.0
HKD2_k127_7645431_2 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 341.0
HKD2_k127_7645431_3 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 322.0
HKD2_k127_7645431_4 PFAM extracellular solute-binding protein family 1 K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 315.0
HKD2_k127_7645431_5 maltose-transporting ATPase activity K15772 - - 0.0000000000000000000000000000000000000000000000005958 185.0
HKD2_k127_7645431_6 Cache domain - - - 0.00000000000000000000000000000000000000000003425 182.0
HKD2_k127_7645431_7 response regulator, receiver - - - 0.00000000000000000000000000000000000009423 163.0
HKD2_k127_7645431_8 Binding-protein-dependent transport system inner membrane component K02025,K10228 - - 0.000000000000000000000000002868 129.0
HKD2_k127_7645935_0 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 290.0
HKD2_k127_7645935_1 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000002667 227.0
HKD2_k127_7645935_2 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000005284 190.0
HKD2_k127_7678259_0 ATP-dependent transcriptional regulator K03556 - - 2.025e-223 713.0
HKD2_k127_7678259_1 - - - - 0.00000000000000000000000308 106.0
HKD2_k127_7678259_2 - - - - 0.000000000000002177 79.0
HKD2_k127_7678259_3 helix_turn_helix, Lux Regulon K03556 - - 0.00000009445 53.0
HKD2_k127_7692969_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1095.0
HKD2_k127_7700969_0 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 326.0
HKD2_k127_7700969_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 293.0
HKD2_k127_7700969_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002159 259.0
HKD2_k127_7700969_3 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
HKD2_k127_7700969_4 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000001187 216.0
HKD2_k127_7708697_0 ATP-dependent transcriptional regulator K03556 - - 2.933e-230 742.0
HKD2_k127_7708697_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 7.119e-204 648.0
HKD2_k127_7708697_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 325.0
HKD2_k127_7708697_3 - - - - 0.000000000000000000001964 99.0
HKD2_k127_7708697_4 - - - - 0.00000000000000000002389 92.0
HKD2_k127_7708697_6 Domain of unknown function (DUF333) K09712 - - 0.000000000000000004738 91.0
HKD2_k127_7708697_7 Psort location Cytoplasmic, score - - - 0.000000000000000005284 94.0
HKD2_k127_7714877_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.265e-216 681.0
HKD2_k127_7714877_1 - - - - 0.0000000000000000000000000000000000000001589 164.0
HKD2_k127_7714877_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000228 97.0
HKD2_k127_7714963_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 422.0
HKD2_k127_7714963_1 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 362.0
HKD2_k127_7714963_2 heme binding K21472 - - 0.00000000000000000000000000000000000000000000000000000000000000003932 231.0
HKD2_k127_7714963_3 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000003213 199.0
HKD2_k127_7714963_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000008964 86.0
HKD2_k127_7714963_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000001245 70.0
HKD2_k127_7761705_0 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 427.0
HKD2_k127_7761705_1 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 400.0
HKD2_k127_7761705_10 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000001884 160.0
HKD2_k127_7761705_11 Protein of unknown function (DUF2892) - - - 0.0000000000000000533 83.0
HKD2_k127_7761705_12 Acetokinase family K00925 - 2.7.2.1 0.00000000002792 73.0
HKD2_k127_7761705_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 392.0
HKD2_k127_7761705_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 353.0
HKD2_k127_7761705_4 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 338.0
HKD2_k127_7761705_5 Sodium/calcium exchanger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 308.0
HKD2_k127_7761705_6 PFAM SMC domain protein K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009396 289.0
HKD2_k127_7761705_7 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000001696 222.0
HKD2_k127_7761705_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001774 233.0
HKD2_k127_7761705_9 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000000000000002161 214.0
HKD2_k127_7778289_0 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 473.0
HKD2_k127_7778289_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000001688 177.0
HKD2_k127_7778289_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000006689 164.0
HKD2_k127_783232_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
HKD2_k127_783232_1 arylsulfatase activity - - - 0.000000000000000000000000000000000003638 155.0
HKD2_k127_783232_2 arylsulfatase activity - - - 0.000000000000000000000000000000000004941 152.0
HKD2_k127_783232_3 arylsulfatase activity - - - 0.00000000000000000000000000000009928 141.0
HKD2_k127_7835360_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 526.0
HKD2_k127_7835360_1 Double zinc ribbon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
HKD2_k127_7835360_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 314.0
HKD2_k127_7835360_3 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009193 276.0
HKD2_k127_7835360_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002707 234.0
HKD2_k127_7835360_5 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000004453 155.0
HKD2_k127_7835360_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000009149 152.0
HKD2_k127_7835360_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000008556 146.0
HKD2_k127_7835360_8 thiamine diphosphate biosynthetic process K03154 - - 0.00001608 50.0
HKD2_k127_7863941_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 9.992e-212 675.0
HKD2_k127_7863941_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 1.676e-199 636.0
HKD2_k127_7863941_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 562.0
HKD2_k127_7863941_3 Terminase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
HKD2_k127_7863941_4 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006511 235.0
HKD2_k127_7863941_5 serine-type endopeptidase activity K04772,K08372 - - 0.000000000000000000000000000001396 139.0
HKD2_k127_7863941_6 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000133 113.0
HKD2_k127_7863941_7 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00001069 55.0
HKD2_k127_7863941_8 Kelch repeat-containing protein - - - 0.0001985 52.0
HKD2_k127_78677_0 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 567.0
HKD2_k127_78677_1 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 529.0
HKD2_k127_78677_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 289.0
HKD2_k127_78677_11 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008755 261.0
HKD2_k127_78677_12 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000078 216.0
HKD2_k127_78677_13 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000003148 213.0
HKD2_k127_78677_14 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000002836 195.0
HKD2_k127_78677_15 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000002985 188.0
HKD2_k127_78677_16 Sulfotransferase domain - - - 0.00000000000000000000000000000000001038 147.0
HKD2_k127_78677_17 Sulfotransferase domain - - - 0.000000000000000000000000000003496 130.0
HKD2_k127_78677_2 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 512.0
HKD2_k127_78677_3 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 447.0
HKD2_k127_78677_4 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 442.0
HKD2_k127_78677_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009891 381.0
HKD2_k127_78677_6 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 368.0
HKD2_k127_78677_7 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 348.0
HKD2_k127_78677_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 350.0
HKD2_k127_78677_9 cytidylyl-transferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 302.0
HKD2_k127_7914814_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 3.51e-214 669.0
HKD2_k127_7914814_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 528.0
HKD2_k127_7914814_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 497.0
HKD2_k127_7914814_3 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 417.0
HKD2_k127_7914814_4 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 325.0
HKD2_k127_7914814_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002065 279.0
HKD2_k127_7914814_6 PFAM Sporulation stage II, protein E C-terminal K07315 - 3.1.3.3 0.0002817 44.0
HKD2_k127_7926825_0 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 380.0
HKD2_k127_7926825_1 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 332.0
HKD2_k127_7937842_0 SMART AAA ATPase - - - 3.36e-228 713.0
HKD2_k127_7937842_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 522.0
HKD2_k127_7937842_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 428.0
HKD2_k127_7937842_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 377.0
HKD2_k127_7937842_4 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000002057 160.0
HKD2_k127_7960617_0 xylulokinase activity K00854 - 2.7.1.17 3.96e-213 672.0
HKD2_k127_7960617_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 377.0
HKD2_k127_7960617_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 321.0
HKD2_k127_7960617_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003044 204.0
HKD2_k127_7960617_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000002079 181.0
HKD2_k127_7960617_5 - - - - 0.000000000001425 70.0
HKD2_k127_7960617_6 - K14340 - - 0.000000006812 66.0
HKD2_k127_8047333_0 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000007843 163.0
HKD2_k127_8047333_1 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.00000000003059 71.0
HKD2_k127_8065954_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.028e-256 795.0
HKD2_k127_8065954_1 Pyridoxal-phosphate dependent enzyme - - - 9.298e-250 777.0
HKD2_k127_8065954_11 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000009516 214.0
HKD2_k127_8065954_12 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000001412 203.0
HKD2_k127_8065954_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002529 170.0
HKD2_k127_8065954_14 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000002254 128.0
HKD2_k127_8065954_15 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000006534 98.0
HKD2_k127_8065954_16 aminopeptidase activity - - - 0.0000000000009529 80.0
HKD2_k127_8065954_17 GNAT family acetyltransferase - - - 0.0000005617 61.0
HKD2_k127_8065954_2 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 1.573e-212 669.0
HKD2_k127_8065954_3 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 8.753e-196 623.0
HKD2_k127_8065954_4 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 606.0
HKD2_k127_8065954_5 alpha amylase, catalytic K01208,K11991 - 3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 417.0
HKD2_k127_8065954_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 368.0
HKD2_k127_8065954_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 340.0
HKD2_k127_8065954_8 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004064 287.0
HKD2_k127_8065954_9 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000125 273.0
HKD2_k127_8070909_0 PFAM NHL repeat containing protein - - - 0.0 1117.0
HKD2_k127_8070909_1 elongation factor Tu domain 2 protein K02355 - - 6.747e-311 962.0
HKD2_k127_8087076_0 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 382.0
HKD2_k127_8087076_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 342.0
HKD2_k127_8087076_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000105 203.0
HKD2_k127_8087076_3 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000001354 156.0
HKD2_k127_8087076_4 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000001961 134.0
HKD2_k127_8087076_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000001438 93.0
HKD2_k127_8087076_6 PFAM Forkhead-associated protein - - - 0.0000000000000001162 90.0
HKD2_k127_8181187_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 416.0
HKD2_k127_8181187_1 peptidyl-tyrosine sulfation - - - 0.000000000002688 79.0
HKD2_k127_8217266_0 PFAM ABC transporter related K06158 - - 1.075e-220 704.0
HKD2_k127_8217266_1 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 586.0
HKD2_k127_8217266_10 PFAM transglutaminase domain protein - - - 0.00000000001107 77.0
HKD2_k127_8217266_11 PFAM TPR repeat-containing protein - - - 0.00000000001364 68.0
HKD2_k127_8217266_12 Oxidoreductase family, C-terminal alpha/beta domain K16044 - 1.1.1.371 0.0004827 43.0
HKD2_k127_8217266_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 555.0
HKD2_k127_8217266_3 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 434.0
HKD2_k127_8217266_4 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 423.0
HKD2_k127_8217266_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 405.0
HKD2_k127_8217266_6 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001103 260.0
HKD2_k127_8217266_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000002107 196.0
HKD2_k127_8217266_8 Putative inner membrane exporter, YdcZ K09936 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000007007 158.0
HKD2_k127_8217266_9 - - - - 0.0000000000000000001108 95.0
HKD2_k127_8217729_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000001564 258.0
HKD2_k127_8217729_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000002383 220.0
HKD2_k127_8217729_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
HKD2_k127_8217729_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000001205 199.0
HKD2_k127_8217729_4 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000002675 156.0
HKD2_k127_8217729_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006436 100.0
HKD2_k127_8217729_6 Lysin motif - - - 0.0004377 51.0
HKD2_k127_8269007_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001382 268.0
HKD2_k127_8269007_1 chitinase K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000002784 234.0
HKD2_k127_8269007_2 phospholipase C K21302 - 3.1.3.64 0.00000000000000000000000000000000000000000000000000000006322 209.0
HKD2_k127_8269007_3 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000008821 157.0
HKD2_k127_8283291_0 Major facilitator superfamily - - - 1.163e-196 644.0
HKD2_k127_8283291_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000437 123.0
HKD2_k127_8291679_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 1.557e-204 644.0
HKD2_k127_8291679_1 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 460.0
HKD2_k127_8291679_10 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000002631 220.0
HKD2_k127_8291679_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000000000003629 212.0
HKD2_k127_8291679_12 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000003151 154.0
HKD2_k127_8291679_13 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000009477 132.0
HKD2_k127_8291679_14 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000000002801 104.0
HKD2_k127_8291679_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000005979 107.0
HKD2_k127_8291679_16 GIY-YIG catalytic domain K07461 - - 0.000000000000000000009818 94.0
HKD2_k127_8291679_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00003513 57.0
HKD2_k127_8291679_2 polysaccharide biosynthetic process K16694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 440.0
HKD2_k127_8291679_3 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 426.0
HKD2_k127_8291679_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 377.0
HKD2_k127_8291679_5 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 310.0
HKD2_k127_8291679_6 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 300.0
HKD2_k127_8291679_7 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
HKD2_k127_8291679_9 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
HKD2_k127_83367_0 Heat shock 70 kDa protein K04043 - - 3.055e-199 628.0
HKD2_k127_83367_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 575.0
HKD2_k127_83367_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 496.0
HKD2_k127_83367_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 370.0
HKD2_k127_83367_4 Diguanylate cyclase and metal dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000004821 242.0
HKD2_k127_83367_5 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000496 178.0
HKD2_k127_83367_6 Transcriptional regulator PadR-like family K10947 - - 0.0000000000000000000000000007666 115.0
HKD2_k127_83367_7 Peptidase M48 - - - 0.00000000000000000000002634 109.0
HKD2_k127_83367_8 alcohol dehydrogenase - - - 0.0000000000000025 87.0
HKD2_k127_8344829_0 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 392.0
HKD2_k127_8344829_3 - - - - 0.0000000000000007751 85.0
HKD2_k127_839929_0 ethanolamine catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 317.0
HKD2_k127_839929_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 308.0
HKD2_k127_839929_2 ethanolamine catabolic process K04024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
HKD2_k127_839929_3 cellular response to dsDNA K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008139 262.0
HKD2_k127_839929_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000001468 94.0
HKD2_k127_839929_5 Patatin-like phospholipase K07001 - - 0.000000000000000001303 94.0
HKD2_k127_839929_6 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000003436 78.0
HKD2_k127_839929_8 - - - - 0.000000000001463 72.0
HKD2_k127_839929_9 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.000003549 49.0
HKD2_k127_8402925_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 392.0
HKD2_k127_8402925_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000004338 173.0
HKD2_k127_8417245_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 490.0
HKD2_k127_8417245_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 295.0
HKD2_k127_8417245_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
HKD2_k127_843931_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 5.841e-236 738.0
HKD2_k127_843931_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 458.0
HKD2_k127_843931_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 344.0
HKD2_k127_843931_3 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 311.0
HKD2_k127_843931_4 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006014 258.0
HKD2_k127_843931_5 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000005468 242.0
HKD2_k127_8462320_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.033e-210 661.0
HKD2_k127_8462320_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 380.0
HKD2_k127_8462320_2 PFAM YbbR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 359.0
HKD2_k127_8462320_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 348.0
HKD2_k127_8462320_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000001235 185.0
HKD2_k127_8462320_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00001303 50.0
HKD2_k127_8462320_6 - - - - 0.0007365 43.0
HKD2_k127_8593806_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2036.0
HKD2_k127_8593806_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1107.0
HKD2_k127_8593806_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003647 214.0
HKD2_k127_8593806_11 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000004522 171.0
HKD2_k127_8593806_12 Transcriptional regulator - - - 0.00000000000000000000000000000000000000002642 157.0
HKD2_k127_8593806_2 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 342.0
HKD2_k127_8593806_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 327.0
HKD2_k127_8593806_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 316.0
HKD2_k127_8593806_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 308.0
HKD2_k127_8593806_6 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 313.0
HKD2_k127_8593806_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 307.0
HKD2_k127_8593806_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000134 250.0
HKD2_k127_8593806_9 Domain of unknown function (DUF348) - - - 0.000000000000000000000000000000000000000000000000000000000000000001419 241.0
HKD2_k127_8605933_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 512.0
HKD2_k127_8605933_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 448.0
HKD2_k127_8605933_2 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
HKD2_k127_8605933_3 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HKD2_k127_8605933_4 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000001885 194.0
HKD2_k127_8636880_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 432.0
HKD2_k127_8636880_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 421.0
HKD2_k127_8636880_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 394.0
HKD2_k127_8636880_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 390.0
HKD2_k127_8636880_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 376.0
HKD2_k127_8636880_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 320.0
HKD2_k127_8636880_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 301.0
HKD2_k127_8636880_7 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
HKD2_k127_8636880_8 PFAM Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000007518 159.0
HKD2_k127_8636880_9 - - - - 0.0000000000000000000000000000000000006837 143.0
HKD2_k127_8670792_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 321.0
HKD2_k127_8670792_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001684 263.0
HKD2_k127_8670792_2 Putative tRNA binding domain K06878 - - 0.0000000000000000000000000000000000000000000000000004481 186.0
HKD2_k127_8670792_3 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000000001915 184.0
HKD2_k127_8670792_4 - - - - 0.000000000000000000000000000000000000000000000001835 177.0
HKD2_k127_8670792_5 Helix-turn-helix domain K07729 - - 0.0000000000000000000000000005233 115.0
HKD2_k127_8670792_6 Leucine carboxyl methyltransferase - - - 0.00000000000000001974 86.0
HKD2_k127_8687408_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 344.0
HKD2_k127_8687408_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003764 282.0
HKD2_k127_8689383_0 UPF0313 protein - - - 3.684e-232 728.0
HKD2_k127_8689383_1 Domain of unknown function DUF87 K06915 - - 4.959e-197 629.0
HKD2_k127_8689383_2 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 296.0
HKD2_k127_8689383_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000008029 219.0
HKD2_k127_8689383_5 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000000005635 207.0
HKD2_k127_8689383_6 NurA - - - 0.00000000000000000000748 105.0
HKD2_k127_8768381_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.082e-241 768.0
HKD2_k127_8768381_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 1.478e-241 752.0
HKD2_k127_8768381_10 Psort location CytoplasmicMembrane, score - - - 0.0005513 51.0
HKD2_k127_8768381_2 formate dehydrogenase (NAD+) activity K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 608.0
HKD2_k127_8768381_3 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 520.0
HKD2_k127_8768381_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
HKD2_k127_8768381_5 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 328.0
HKD2_k127_8768381_6 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 319.0
HKD2_k127_8768381_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000002349 140.0
HKD2_k127_8768381_8 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.000000000000000000000000000001341 126.0
HKD2_k127_8768381_9 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000004475 110.0
HKD2_k127_8805641_0 Formate/nitrite transporter K06212 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 338.0
HKD2_k127_8805641_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 293.0
HKD2_k127_8805641_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000004987 186.0
HKD2_k127_8825707_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 458.0
HKD2_k127_8825707_1 transferase activity, transferring glycosyl groups K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001705 284.0
HKD2_k127_8825707_2 arylsulfatase activity - - - 0.000000000000000000000000000000000004908 149.0
HKD2_k127_8845046_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009787 255.0
HKD2_k127_8845046_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009965 237.0
HKD2_k127_8845046_2 - - - - 0.0000000000000000000000000000000000000000000000000003715 193.0
HKD2_k127_8845046_3 - - - - 0.000000000000000000000000001161 123.0
HKD2_k127_8845046_4 - - - - 0.00000001982 61.0
HKD2_k127_8892863_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 385.0
HKD2_k127_8892863_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
HKD2_k127_8892863_2 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000007997 188.0
HKD2_k127_8892863_3 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.000000001789 66.0
HKD2_k127_8900419_0 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 546.0
HKD2_k127_8900419_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 471.0
HKD2_k127_8900419_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
HKD2_k127_8900419_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000579 218.0
HKD2_k127_8900419_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000004525 197.0
HKD2_k127_8900419_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000005303 142.0
HKD2_k127_8900419_6 Ribosomal protein S21 K02970 - - 0.00000000000000000000000231 103.0
HKD2_k127_8900419_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000313 107.0
HKD2_k127_8900419_8 Type III secretion system lipoprotein chaperone (YscW) - - - 0.0000000000000000000392 102.0
HKD2_k127_8944291_0 Spermine/spermidine synthase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 545.0
HKD2_k127_8944291_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000006769 220.0
HKD2_k127_8944291_2 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000007939 117.0
HKD2_k127_8978613_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 299.0
HKD2_k127_8978613_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 288.0
HKD2_k127_8978613_2 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000005697 241.0
HKD2_k127_8978613_3 zinc ion binding K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000573 248.0
HKD2_k127_9073708_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 601.0
HKD2_k127_9073708_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 323.0
HKD2_k127_9073708_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000005104 207.0
HKD2_k127_9073708_3 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000000000009836 190.0
HKD2_k127_9073708_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000001463 159.0
HKD2_k127_9073708_5 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000006593 111.0
HKD2_k127_9073708_6 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001032 107.0
HKD2_k127_9073708_7 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000009651 89.0
HKD2_k127_912801_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 582.0
HKD2_k127_912801_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
HKD2_k127_912801_10 PFAM SH3 type 3 domain protein - - - 0.0000001405 63.0
HKD2_k127_912801_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 399.0
HKD2_k127_912801_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 365.0
HKD2_k127_912801_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 341.0
HKD2_k127_912801_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
HKD2_k127_912801_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009262 278.0
HKD2_k127_912801_7 PFAM sugar transferase K13012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009301 261.0
HKD2_k127_912801_8 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
HKD2_k127_912801_9 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.000000000000000000001097 107.0
HKD2_k127_9139229_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 474.0
HKD2_k127_9139229_1 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 326.0
HKD2_k127_9143691_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.065e-234 732.0
HKD2_k127_9143691_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.317e-225 709.0
HKD2_k127_9143691_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000002249 129.0
HKD2_k127_9143691_3 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000004084 117.0
HKD2_k127_9327666_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 434.0
HKD2_k127_9327666_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 431.0
HKD2_k127_9327666_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000001297 181.0
HKD2_k127_9327666_3 - - - - 0.0000000000000000000000000000000000001556 159.0
HKD2_k127_9327666_4 ABC-2 family transporter protein - - - 0.00000000009285 64.0
HKD2_k127_936617_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 567.0
HKD2_k127_936617_1 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
HKD2_k127_936617_2 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000002822 224.0
HKD2_k127_936617_3 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000002228 161.0
HKD2_k127_9372092_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.367e-209 656.0
HKD2_k127_9372092_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 591.0
HKD2_k127_9372092_10 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 304.0
HKD2_k127_9372092_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 292.0
HKD2_k127_9372092_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000584 239.0
HKD2_k127_9372092_13 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
HKD2_k127_9372092_15 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000005118 237.0
HKD2_k127_9372092_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
HKD2_k127_9372092_17 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000002283 213.0
HKD2_k127_9372092_18 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000004437 194.0
HKD2_k127_9372092_19 - - - - 0.00000000000000000000000000000000000000000000000001128 188.0
HKD2_k127_9372092_2 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 548.0
HKD2_k127_9372092_20 GtrA-like protein - - - 0.00000000000000000000000000000000000000000006978 165.0
HKD2_k127_9372092_21 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000005592 151.0
HKD2_k127_9372092_22 - - - - 0.00000000000000000000000000000000002879 145.0
HKD2_k127_9372092_23 - - - - 0.0000000000000000000000000000000007509 135.0
HKD2_k127_9372092_24 gas vesicle protein - - - 0.0000000000000000001889 92.0
HKD2_k127_9372092_3 pathogenesis K21471,K21687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
HKD2_k127_9372092_4 SMART AAA ATPase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 448.0
HKD2_k127_9372092_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 434.0
HKD2_k127_9372092_6 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 376.0
HKD2_k127_9372092_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 366.0
HKD2_k127_9372092_8 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
HKD2_k127_9372092_9 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 343.0
HKD2_k127_9549326_0 Serine threonine protein kinase K12132 - 2.7.11.1 5.707e-199 627.0
HKD2_k127_9549326_1 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 422.0
HKD2_k127_9549326_2 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 390.0
HKD2_k127_9549326_3 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 371.0
HKD2_k127_9549326_4 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
HKD2_k127_9549326_5 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
HKD2_k127_9549326_6 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000000000000000000002485 184.0
HKD2_k127_9549326_7 - - - - 0.000000000000000000000000000002245 121.0
HKD2_k127_9557170_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 7.313e-259 802.0
HKD2_k127_9557170_1 Belongs to the binding-protein-dependent transport system permease family K10547 - - 0.0000000001312 62.0
HKD2_k127_9639950_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 473.0
HKD2_k127_9639950_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 361.0
HKD2_k127_9639950_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000004839 181.0
HKD2_k127_9639950_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000001293 171.0
HKD2_k127_9671715_0 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 356.0
HKD2_k127_9671715_1 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000000000000000000000000839 189.0
HKD2_k127_9671715_2 - - - - 0.00000000000000000000000000000000000003135 148.0
HKD2_k127_9671715_3 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.00000000000000000000002089 102.0
HKD2_k127_9671715_4 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000007146 49.0
HKD2_k127_9683405_0 Protein of unknown function (DUF554) K07150 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007697 267.0
HKD2_k127_9683405_1 protein modification by small protein conjugation - - - 0.0000000000000000000000000000000000000001511 161.0
HKD2_k127_9683405_2 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000001292 143.0
HKD2_k127_9683405_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000003075 131.0
HKD2_k127_9683405_4 transmembrane transport K22044 GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - 0.00000000000000000000000002285 119.0
HKD2_k127_9683405_5 PFAM Mov34 MPN PAD-1 family - - - 0.00000000000000000002187 100.0
HKD2_k127_9683405_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000006429 94.0
HKD2_k127_9683405_7 von Willebrand factor type A domain K07114 - - 0.00000000000001015 86.0
HKD2_k127_9683405_8 WXG100 protein secretion system (Wss), protein YukD - - - 0.0000000001904 65.0
HKD2_k127_9683405_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000008726 57.0
HKD2_k127_9787908_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 605.0
HKD2_k127_9787908_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000008307 112.0
HKD2_k127_9853413_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 530.0
HKD2_k127_9853413_1 Psort location Cytoplasmic, score K00848,K00879 - 2.7.1.5,2.7.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 436.0
HKD2_k127_9853413_2 xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
HKD2_k127_9853413_3 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 316.0
HKD2_k127_9853413_4 Transcriptional regulator DeoR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 274.0
HKD2_k127_9853413_5 pfkB family carbohydrate kinase K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
HKD2_k127_9853413_6 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
HKD2_k127_9853413_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
HKD2_k127_9853413_8 Acyl-transferase - - - 0.00000000000000000000000000001014 129.0
HKD2_k127_9853413_9 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 0.0000000000003433 69.0
HKD2_k127_9857878_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 580.0
HKD2_k127_9857878_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 518.0
HKD2_k127_9857878_2 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
HKD2_k127_9857878_3 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 388.0
HKD2_k127_9857878_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000002293 196.0
HKD2_k127_9868020_0 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 387.0
HKD2_k127_9868020_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001592 282.0
HKD2_k127_9868020_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
HKD2_k127_9868020_3 Belongs to the carbohydrate kinase PfkB family K00847 GO:0003674,GO:0003824,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0005975,GO:0005996,GO:0006000,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008865,GO:0009506,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0030054,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0055044,GO:0071704,GO:0071944 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000006998 231.0
HKD2_k127_9868020_4 Sucrose-6F-phosphate phosphohydrolase - - - 0.0000000000002298 79.0
HKD2_k127_9873590_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1185.0
HKD2_k127_9873590_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 363.0
HKD2_k127_9873590_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
HKD2_k127_9873590_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD2_k127_9908840_0 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 3.091e-283 886.0
HKD2_k127_9908840_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.81e-221 711.0
HKD2_k127_9908840_2 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HKD2_k127_9908840_3 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000005247 180.0
HKD2_k127_9908840_4 AntiSigma factor - - - 0.00000000000007962 82.0
HKD2_k127_9935697_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.067e-194 615.0
HKD2_k127_9935697_1 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 417.0
HKD2_k127_9935697_2 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 347.0
HKD2_k127_9935697_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 329.0
HKD2_k127_9935697_4 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 318.0
HKD2_k127_9935697_5 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
HKD2_k127_9935697_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000002932 148.0
HKD2_k127_9945319_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 407.0
HKD2_k127_9945319_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 343.0
HKD2_k127_9945319_2 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 335.0
HKD2_k127_9945319_3 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001996 267.0
HKD2_k127_9945319_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000003393 197.0
HKD2_k127_9945319_5 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000008028 167.0
HKD2_k127_9945319_6 - - - - 0.000000000000000000000000000000000000002697 153.0
HKD2_k127_9945319_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000006013 121.0
HKD2_k127_9945319_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000001045 121.0
HKD2_k127_996039_0 Heavy-metal-associated domain K01534 - 3.6.3.3,3.6.3.5 4.676e-243 773.0
HKD2_k127_996039_1 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
HKD2_k127_996039_2 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000503 231.0
HKD2_k127_996039_3 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000004346 220.0
HKD2_k127_996039_4 - - - - 0.00005292 57.0