Overview

ID MAG01826
Name HKD2_bin.88
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus UBA5189
Species
Assembly information
Completeness (%) 59.05
Contamination (%) 0.06
GC content (%) 73.0
N50 (bp) 16,492
Genome size (bp) 1,669,524

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1435

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10166182_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 367.0
HKD2_k127_10166182_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 364.0
HKD2_k127_10166182_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000001293 127.0
HKD2_k127_10166182_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001964 114.0
HKD2_k127_10166182_12 Universal bacterial protein YeaZ K14742 - - 0.000000000000001972 87.0
HKD2_k127_10166182_13 - - - - 0.00000008213 64.0
HKD2_k127_10166182_14 Carbohydrate kinase - - - 0.0000004623 63.0
HKD2_k127_10166182_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000001002 242.0
HKD2_k127_10166182_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000001863 218.0
HKD2_k127_10166182_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000001708 218.0
HKD2_k127_10166182_5 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000002616 207.0
HKD2_k127_10166182_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000006741 204.0
HKD2_k127_10166182_7 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000005828 166.0
HKD2_k127_10166182_8 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000003995 159.0
HKD2_k127_10166182_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000009317 145.0
HKD2_k127_119250_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 572.0
HKD2_k127_119250_1 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 518.0
HKD2_k127_119250_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000007725 199.0
HKD2_k127_119250_11 SnoaL-like polyketide cyclase K15945 - - 0.0000000000000000000000000000000000000000000000004542 190.0
HKD2_k127_119250_12 Cyclic-di-AMP receptor - - - 0.0000000000000000000000000000002278 127.0
HKD2_k127_119250_13 ECF sigma factor K03088 - - 0.000000000000000000000002351 109.0
HKD2_k127_119250_14 nUDIX hydrolase K01515,K08310 - 3.6.1.13,3.6.1.67 0.00000000000000003526 93.0
HKD2_k127_119250_15 Diguanylate cyclase - - - 0.000000000000002445 87.0
HKD2_k127_119250_16 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta - - - 0.000000000000005229 83.0
HKD2_k127_119250_17 MarR family - - - 0.0000000001391 71.0
HKD2_k127_119250_18 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000003991 65.0
HKD2_k127_119250_19 - - - - 0.0000007504 62.0
HKD2_k127_119250_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 462.0
HKD2_k127_119250_20 Pfam:DUF385 - - - 0.000002355 56.0
HKD2_k127_119250_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 438.0
HKD2_k127_119250_4 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 390.0
HKD2_k127_119250_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 316.0
HKD2_k127_119250_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003745 250.0
HKD2_k127_119250_7 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001101 250.0
HKD2_k127_119250_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000001024 204.0
HKD2_k127_119250_9 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000004584 218.0
HKD2_k127_128537_0 )-transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 390.0
HKD2_k127_128537_1 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000012 209.0
HKD2_k127_128537_2 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000001457 187.0
HKD2_k127_128537_3 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) K05845 - - 0.0000000000000000000000000000000000000000000005886 178.0
HKD2_k127_128537_5 Oxidoreductase molybdopterin binding domain K07147 - - 0.000000101 54.0
HKD2_k127_128537_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000003868 61.0
HKD2_k127_1290321_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 465.0
HKD2_k127_1290321_1 TOBE domain K02045,K02052 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 362.0
HKD2_k127_1290321_2 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 325.0
HKD2_k127_1290321_3 binding-protein-dependent transport systems inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000388 249.0
HKD2_k127_1290321_4 ABC transporter (Permease) K02053 - - 0.000000000000000000000000000000000000000000000000000000000000005266 228.0
HKD2_k127_1290321_5 Domain of unknown function (DUF1727) - - - 0.000000000000000000000000000000000000002395 157.0
HKD2_k127_1290321_6 TRANSCRIPTIONal - - - 0.0000000000000000000002923 111.0
HKD2_k127_1294723_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 447.0
HKD2_k127_1294723_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 408.0
HKD2_k127_1294723_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
HKD2_k127_1294723_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000001191 164.0
HKD2_k127_1294723_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000001707 115.0
HKD2_k127_1294723_5 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000003815 117.0
HKD2_k127_1294723_6 Sigma-70, region 4 K03088 - - 0.000000000000001197 91.0
HKD2_k127_1294723_7 amine dehydrogenase activity - - - 0.0000000000006593 81.0
HKD2_k127_1353658_0 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 496.0
HKD2_k127_1353658_1 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 421.0
HKD2_k127_1353658_10 ABC-type multidrug transport system, permease component K01992 - - 0.000801 49.0
HKD2_k127_1353658_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 383.0
HKD2_k127_1353658_3 phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000434 284.0
HKD2_k127_1353658_4 Flavodoxin K03809 - 1.6.5.2 0.00000000000000000000000000000000000004003 151.0
HKD2_k127_1353658_5 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000005002 122.0
HKD2_k127_1353658_6 Memo-like protein K06990 - - 0.000000000000000000000000007048 128.0
HKD2_k127_1353658_7 Alkylmercury lyase - - - 0.0000000000000000000000119 107.0
HKD2_k127_1353658_8 Alkylmercury lyase - - - 0.000000000000003202 77.0
HKD2_k127_1353658_9 AMMECR1 K06990 - - 0.0000000000001667 78.0
HKD2_k127_1369013_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.053e-195 644.0
HKD2_k127_1369013_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 467.0
HKD2_k127_1369013_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 310.0
HKD2_k127_1369013_11 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 295.0
HKD2_k127_1369013_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
HKD2_k127_1369013_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009267 262.0
HKD2_k127_1369013_14 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000002066 224.0
HKD2_k127_1369013_15 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000002991 123.0
HKD2_k127_1369013_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000354 116.0
HKD2_k127_1369013_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000003492 78.0
HKD2_k127_1369013_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 466.0
HKD2_k127_1369013_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 449.0
HKD2_k127_1369013_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 411.0
HKD2_k127_1369013_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 381.0
HKD2_k127_1369013_6 Evidence 2b Function of strongly homologous gene K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 359.0
HKD2_k127_1369013_7 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 343.0
HKD2_k127_1369013_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 352.0
HKD2_k127_1369013_9 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 333.0
HKD2_k127_1482904_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1079.0
HKD2_k127_1482904_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
HKD2_k127_1482904_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003367 270.0
HKD2_k127_1482904_3 Heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000007224 228.0
HKD2_k127_1482904_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000001392 98.0
HKD2_k127_1514110_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
HKD2_k127_1514110_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 400.0
HKD2_k127_1514110_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000009378 241.0
HKD2_k127_1514110_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001122 214.0
HKD2_k127_1514110_4 Protein of unknown function (DUF1290) - - - 0.000000000000000000000005365 114.0
HKD2_k127_1514110_5 Belongs to the D-alanine--D-alanine ligase family K01921 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.4 0.00000000000000002828 84.0
HKD2_k127_1514110_6 Belongs to the UPF0235 family K09131 - - 0.00000000003479 70.0
HKD2_k127_1514110_7 Cell division protein FtsQ K03589 - - 0.0001053 53.0
HKD2_k127_171654_0 cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 372.0
HKD2_k127_171654_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 318.0
HKD2_k127_171654_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000001883 246.0
HKD2_k127_171654_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000003144 132.0
HKD2_k127_171654_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000007317 93.0
HKD2_k127_171654_5 Baseplate J-like protein K01218 - 3.2.1.78 0.000000001068 72.0
HKD2_k127_1791562_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1080.0
HKD2_k127_1791562_1 helicase superfamily c-terminal domain K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 459.0
HKD2_k127_1791562_10 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000001415 119.0
HKD2_k127_1791562_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000008586 111.0
HKD2_k127_1791562_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000008803 119.0
HKD2_k127_1791562_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002553 99.0
HKD2_k127_1791562_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 423.0
HKD2_k127_1791562_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 333.0
HKD2_k127_1791562_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HKD2_k127_1791562_5 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004857 252.0
HKD2_k127_1791562_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000647 203.0
HKD2_k127_1791562_7 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000003462 173.0
HKD2_k127_1791562_8 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000000000002883 183.0
HKD2_k127_1791562_9 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000001334 143.0
HKD2_k127_2003839_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 295.0
HKD2_k127_2003839_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005506 282.0
HKD2_k127_2003839_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001314 213.0
HKD2_k127_2003839_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000003267 149.0
HKD2_k127_200444_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.184e-269 874.0
HKD2_k127_200444_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 607.0
HKD2_k127_200444_10 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 344.0
HKD2_k127_200444_11 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 314.0
HKD2_k127_200444_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 314.0
HKD2_k127_200444_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003972 290.0
HKD2_k127_200444_14 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006964 258.0
HKD2_k127_200444_15 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000781 230.0
HKD2_k127_200444_16 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000003282 218.0
HKD2_k127_200444_17 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000479 209.0
HKD2_k127_200444_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000831 219.0
HKD2_k127_200444_19 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000003828 194.0
HKD2_k127_200444_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 550.0
HKD2_k127_200444_20 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000002979 199.0
HKD2_k127_200444_21 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000002858 189.0
HKD2_k127_200444_22 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000009461 188.0
HKD2_k127_200444_23 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000007433 167.0
HKD2_k127_200444_24 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000447 161.0
HKD2_k127_200444_25 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000004815 147.0
HKD2_k127_200444_26 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000001544 137.0
HKD2_k127_200444_27 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000009013 135.0
HKD2_k127_200444_28 Yqey-like protein K09117 - - 0.00000000000000000000000005573 113.0
HKD2_k127_200444_29 FR47-like protein - - - 0.0000000000000000000000002029 121.0
HKD2_k127_200444_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 549.0
HKD2_k127_200444_30 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000001142 107.0
HKD2_k127_200444_31 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000007953 98.0
HKD2_k127_200444_32 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000009254 99.0
HKD2_k127_200444_33 Chromate resistance exported protein - - - 0.000000000000000001861 89.0
HKD2_k127_200444_34 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001418 83.0
HKD2_k127_200444_35 Chromate resistance exported protein - - - 0.0000000000000004892 80.0
HKD2_k127_200444_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 428.0
HKD2_k127_200444_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 416.0
HKD2_k127_200444_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 391.0
HKD2_k127_200444_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 380.0
HKD2_k127_200444_8 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 363.0
HKD2_k127_200444_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 359.0
HKD2_k127_2005376_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 501.0
HKD2_k127_2005376_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 381.0
HKD2_k127_2005376_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K00874 - 2.7.1.15,2.7.1.4,2.7.1.45 0.0000000004603 70.0
HKD2_k127_2005376_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 348.0
HKD2_k127_2005376_3 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007653 269.0
HKD2_k127_2005376_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003937 254.0
HKD2_k127_2005376_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000124 226.0
HKD2_k127_2005376_6 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000003134 160.0
HKD2_k127_2005376_7 Methyltransferase type 12 - - - 0.00000000000000000000000000000785 137.0
HKD2_k127_2005376_8 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000005241 115.0
HKD2_k127_2005376_9 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000001968 76.0
HKD2_k127_2086332_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 388.0
HKD2_k127_2086332_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
HKD2_k127_2086332_2 electron transfer flavoprotein, alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000004126 218.0
HKD2_k127_2086332_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000001672 166.0
HKD2_k127_2086332_4 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000008635 166.0
HKD2_k127_2086332_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000008625 147.0
HKD2_k127_2086332_6 Thioredoxin-like K02199 - - 0.000000000000000000000000003732 120.0
HKD2_k127_2086332_7 acyl-CoA dehydrogenase - - - 0.0000000000009899 68.0
HKD2_k127_215250_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 441.0
HKD2_k127_215250_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
HKD2_k127_215250_10 YbbR-like protein - - - 0.0000000000000000000000409 113.0
HKD2_k127_215250_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000002684 73.0
HKD2_k127_215250_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 323.0
HKD2_k127_215250_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003013 263.0
HKD2_k127_215250_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.000000000000000000000000000000000000000000000000000000002826 213.0
HKD2_k127_215250_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000002524 199.0
HKD2_k127_215250_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000005696 183.0
HKD2_k127_215250_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000008109 176.0
HKD2_k127_215250_8 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003914 158.0
HKD2_k127_215250_9 PFAM ribosomal protein L17 K02879 - - 0.0000000000000000000000000000008916 126.0
HKD2_k127_216455_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 598.0
HKD2_k127_216455_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 373.0
HKD2_k127_216455_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 346.0
HKD2_k127_216455_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
HKD2_k127_216455_4 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001126 305.0
HKD2_k127_216455_5 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.0002915 50.0
HKD2_k127_2199733_0 family 4 K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 502.0
HKD2_k127_2199733_1 carbohydrate transport K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 362.0
HKD2_k127_2199733_2 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
HKD2_k127_2199733_3 UbiC transcription regulator-associated domain protein K03710 - - 0.000000000000000000000000000000000000000000000000000002214 201.0
HKD2_k127_2199733_4 PFAM Luciferase-like - - - 0.000000000000000000000000000000000000000000000001121 186.0
HKD2_k127_2199733_5 pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000005543 106.0
HKD2_k127_2199733_6 Nucleoside H+ symporter K05820 - - 0.00000000001345 77.0
HKD2_k127_2332352_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 497.0
HKD2_k127_2332352_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 519.0
HKD2_k127_2332352_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 473.0
HKD2_k127_2332352_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 312.0
HKD2_k127_2332352_4 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 303.0
HKD2_k127_2332352_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000009213 241.0
HKD2_k127_2332352_6 CoA-binding protein K06929 - - 0.00000000000000000000000000000003354 138.0
HKD2_k127_2615849_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 6.999e-220 707.0
HKD2_k127_2615849_1 Heat shock 70 kDa protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 367.0
HKD2_k127_2615849_2 GTPases (dynamin-related) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 341.0
HKD2_k127_2615849_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 336.0
HKD2_k127_2615849_4 Dynamin family - GO:0003674,GO:0005215,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015562,GO:0016020,GO:0022857,GO:0030312,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 325.0
HKD2_k127_2615849_5 Protein of unknown function (DUF1524) - - - 0.0000000000000000000000000000000000000000000000000000000000000009692 231.0
HKD2_k127_2615849_6 Anthranilate synthase component I, N terminal region K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000007355 145.0
HKD2_k127_2615849_7 Trehalose utilisation K09992 - - 0.0000000000000000000001922 114.0
HKD2_k127_2615849_8 SMART nuclease (SNase domain protein) K01174 - 3.1.31.1 0.000000000000000000005806 104.0
HKD2_k127_2617091_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 394.0
HKD2_k127_2617091_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 362.0
HKD2_k127_2617091_2 ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 335.0
HKD2_k127_2617091_3 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006691 278.0
HKD2_k127_2617091_4 COG2755 Lysophospholipase L1 and related - - - 0.0000000000000000000000001266 124.0
HKD2_k127_2617337_0 trimethylamine methyltransferase K14083 - 2.1.1.250 3.127e-221 696.0
HKD2_k127_2617337_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 581.0
HKD2_k127_2617337_10 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 266.0
HKD2_k127_2617337_11 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001236 263.0
HKD2_k127_2617337_12 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
HKD2_k127_2617337_13 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
HKD2_k127_2617337_14 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000001732 197.0
HKD2_k127_2617337_15 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000008257 160.0
HKD2_k127_2617337_16 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.000000000000000000000000000000000007062 153.0
HKD2_k127_2617337_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000002551 129.0
HKD2_k127_2617337_18 cell redox homeostasis K02199 - - 0.00000000000000000000000000000277 132.0
HKD2_k127_2617337_19 Pfam Secreted repeat of - - - 0.0000000000000000000000000004789 121.0
HKD2_k127_2617337_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 413.0
HKD2_k127_2617337_20 ArsC family - - - 0.00000000000000000000002222 111.0
HKD2_k127_2617337_21 Domain of unknown function (DUF4349) - - - 0.00000000000000000003078 106.0
HKD2_k127_2617337_22 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000503 66.0
HKD2_k127_2617337_23 transcriptional regulator - - - 0.0000000104 65.0
HKD2_k127_2617337_24 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000002016 65.0
HKD2_k127_2617337_25 SIS domain K00820 - 2.6.1.16 0.0000001208 64.0
HKD2_k127_2617337_26 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.00001045 58.0
HKD2_k127_2617337_27 ACT domain protein - - - 0.0001277 49.0
HKD2_k127_2617337_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 384.0
HKD2_k127_2617337_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 376.0
HKD2_k127_2617337_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 358.0
HKD2_k127_2617337_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 342.0
HKD2_k127_2617337_7 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 327.0
HKD2_k127_2617337_8 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 325.0
HKD2_k127_2617337_9 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 301.0
HKD2_k127_2644434_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1030.0
HKD2_k127_2644434_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 421.0
HKD2_k127_2644434_2 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000006276 178.0
HKD2_k127_2644434_3 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000006951 143.0
HKD2_k127_2657453_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1292.0
HKD2_k127_2657453_1 - - - - 0.000000000000000000000000000003612 129.0
HKD2_k127_2657453_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000001713 115.0
HKD2_k127_2657453_3 Urate oxidase N-terminal - - - 0.00002824 58.0
HKD2_k127_2670876_0 ABC transporter, transmembrane region K06147 - - 2.874e-270 853.0
HKD2_k127_2670876_1 ABC transporter, transmembrane region K06147 - - 4.646e-221 703.0
HKD2_k127_2670876_2 Sigma-70 region 2 K03088 - - 0.0000000000005123 81.0
HKD2_k127_2670876_3 MarR family transcriptional regulator - - - 0.000000000003223 74.0
HKD2_k127_2670876_4 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000001884 66.0
HKD2_k127_2670876_5 exo-alpha-(2->6)-sialidase activity - - - 0.000001011 61.0
HKD2_k127_2670876_6 Carboxylesterase family - - - 0.00006274 54.0
HKD2_k127_2736682_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 596.0
HKD2_k127_2736682_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 427.0
HKD2_k127_2736682_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 306.0
HKD2_k127_2736682_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000006936 191.0
HKD2_k127_2736682_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000005891 166.0
HKD2_k127_2736682_5 PFAM Peptidase family M23 - - - 0.0000000000000000000000000000000007284 147.0
HKD2_k127_2736682_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000001035 114.0
HKD2_k127_2754706_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 601.0
HKD2_k127_2754706_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 471.0
HKD2_k127_2754706_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
HKD2_k127_2754706_11 SMC proteins Flexible Hinge Domain K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000001472 224.0
HKD2_k127_2754706_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000007885 213.0
HKD2_k127_2754706_13 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000001196 205.0
HKD2_k127_2754706_14 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.00000000000000000000000000000000000000009821 171.0
HKD2_k127_2754706_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000006644 143.0
HKD2_k127_2754706_16 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000001262 147.0
HKD2_k127_2754706_17 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000004446 106.0
HKD2_k127_2754706_18 Belongs to the UPF0109 family K06960 - - 0.000000000000000000004472 96.0
HKD2_k127_2754706_19 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000006631 104.0
HKD2_k127_2754706_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 331.0
HKD2_k127_2754706_20 nuclease activity K07460 - - 0.00000005729 62.0
HKD2_k127_2754706_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 324.0
HKD2_k127_2754706_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
HKD2_k127_2754706_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
HKD2_k127_2754706_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003247 293.0
HKD2_k127_2754706_7 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005397 287.0
HKD2_k127_2754706_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000006482 270.0
HKD2_k127_2754706_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000005335 262.0
HKD2_k127_2852293_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 408.0
HKD2_k127_2852293_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 372.0
HKD2_k127_2852293_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000005188 131.0
HKD2_k127_2852293_11 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000002212 100.0
HKD2_k127_2852293_12 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000004878 97.0
HKD2_k127_2852293_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD2_k127_2852293_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006229 286.0
HKD2_k127_2852293_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 285.0
HKD2_k127_2852293_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009651 274.0
HKD2_k127_2852293_6 PFAM extracellular solute-binding protein family 1 K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000214 269.0
HKD2_k127_2852293_7 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000004018 245.0
HKD2_k127_2852293_8 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000002762 136.0
HKD2_k127_2852293_9 - - - - 0.00000000000000000000000000004841 124.0
HKD2_k127_2883413_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 563.0
HKD2_k127_2883413_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 357.0
HKD2_k127_2883413_2 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000001218 243.0
HKD2_k127_2883413_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000007156 240.0
HKD2_k127_2883413_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000378 236.0
HKD2_k127_2883413_5 membrane transporter protein K07090 - - 0.00000000000000891 84.0
HKD2_k127_2883413_6 Sigma-70, region 4 K03088 - - 0.0000000000003546 73.0
HKD2_k127_2883413_7 Helix-turn-helix domain - - - 0.0000002452 61.0
HKD2_k127_2904335_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 2.27e-219 713.0
HKD2_k127_2904335_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 356.0
HKD2_k127_2904335_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 306.0
HKD2_k127_2904335_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006835 297.0
HKD2_k127_2904335_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000006199 99.0
HKD2_k127_2904335_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000003138 75.0
HKD2_k127_2933732_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 4.98e-203 645.0
HKD2_k127_2933732_1 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 364.0
HKD2_k127_2933732_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002552 264.0
HKD2_k127_2933732_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000001034 206.0
HKD2_k127_2933732_4 Heme copper-type cytochrome quinol oxidase subunit 3 K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000008046 154.0
HKD2_k127_2933732_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000003276 154.0
HKD2_k127_2933732_6 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000006082 147.0
HKD2_k127_2933732_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000002688 115.0
HKD2_k127_2933732_8 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.0000000000000000000000001109 113.0
HKD2_k127_293789_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 506.0
HKD2_k127_293789_1 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 471.0
HKD2_k127_293789_2 Alcohol dehydrogenase GroES-like domain K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 293.0
HKD2_k127_293789_3 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001316 257.0
HKD2_k127_293789_4 - K13652 - - 0.000000000000000000001523 104.0
HKD2_k127_293789_6 - - - - 0.0000000000002157 81.0
HKD2_k127_293789_7 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00001281 53.0
HKD2_k127_3069034_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000007529 235.0
HKD2_k127_3069034_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000001239 232.0
HKD2_k127_3069034_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000001891 231.0
HKD2_k127_3069034_3 (Rhomboid) family K07059 - - 0.000000000000000000000000000000000000000000000000000006819 202.0
HKD2_k127_3069034_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000007722 154.0
HKD2_k127_3069034_5 Glycosyl transferase K00728 - 2.4.1.109 0.000000000000000000000000000001041 143.0
HKD2_k127_3069034_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000001764 134.0
HKD2_k127_3069034_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000003743 125.0
HKD2_k127_3069034_8 protein serine/threonine phosphatase activity - - - 0.00000000004646 76.0
HKD2_k127_3069034_9 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0005538 45.0
HKD2_k127_3080204_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 361.0
HKD2_k127_3080204_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 340.0
HKD2_k127_3080204_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000001641 203.0
HKD2_k127_3080204_3 Nitroreductase family - - - 0.00000000000000000000000000000006082 145.0
HKD2_k127_3080204_4 BAAT Acyl-CoA thioester hydrolase - - - 0.000000000000000000000000003695 125.0
HKD2_k127_3080204_5 CAAX protease self-immunity K07052 - - 0.00000000000000000000006757 114.0
HKD2_k127_3080204_6 Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycocerosates during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis K14728 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000001657 84.0
HKD2_k127_3080204_7 DnaJ molecular chaperone homology domain - - - 0.0000000004397 68.0
HKD2_k127_3080204_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00000001989 66.0
HKD2_k127_3080204_9 FR47-like protein - - - 0.0001465 53.0
HKD2_k127_3100826_0 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 451.0
HKD2_k127_3100826_1 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006009 284.0
HKD2_k127_3100826_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003736 221.0
HKD2_k127_3100826_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000001927 193.0
HKD2_k127_3100826_4 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000001157 172.0
HKD2_k127_3100826_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002961 129.0
HKD2_k127_3100826_6 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000007155 119.0
HKD2_k127_3126665_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 6.525e-250 781.0
HKD2_k127_3126665_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.224e-249 787.0
HKD2_k127_3126665_10 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000009343 261.0
HKD2_k127_3126665_11 Major facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000008183 229.0
HKD2_k127_3126665_12 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008773 220.0
HKD2_k127_3126665_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000002637 233.0
HKD2_k127_3126665_14 membrane - - - 0.000000000000000000000000000000000000000000000000001309 192.0
HKD2_k127_3126665_15 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000005073 175.0
HKD2_k127_3126665_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000001884 157.0
HKD2_k127_3126665_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000822 152.0
HKD2_k127_3126665_18 Membrane - - - 0.0000000000000000000000000000000001854 144.0
HKD2_k127_3126665_19 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.000000000000000000000000000000003567 144.0
HKD2_k127_3126665_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.938e-194 621.0
HKD2_k127_3126665_20 EamA-like transporter family - - - 0.0000000000000000000000000000001136 141.0
HKD2_k127_3126665_21 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000003335 139.0
HKD2_k127_3126665_22 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000001904 137.0
HKD2_k127_3126665_23 Probable zinc-ribbon domain - - - 0.00000000000000000000000000008279 122.0
HKD2_k127_3126665_24 Phosphomethylpyrimidine kinase - - - 0.00000000000000000000000007874 126.0
HKD2_k127_3126665_25 AAA domain - - - 0.00000000000000000000001862 118.0
HKD2_k127_3126665_26 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000001019 105.0
HKD2_k127_3126665_27 PFAM Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000001863 101.0
HKD2_k127_3126665_28 dihydroxyacetone kinase K00863 - 2.7.1.28,2.7.1.29,4.6.1.15 0.000000000000000004086 97.0
HKD2_k127_3126665_29 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor - - - 0.00000000000000003643 89.0
HKD2_k127_3126665_3 Citrate synthase, C-terminal domain K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 572.0
HKD2_k127_3126665_31 - - - - 0.000002669 56.0
HKD2_k127_3126665_32 amine dehydrogenase activity - - - 0.00006061 55.0
HKD2_k127_3126665_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 466.0
HKD2_k127_3126665_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 447.0
HKD2_k127_3126665_6 Dak1 domain K00863,K05878,K05879 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 400.0
HKD2_k127_3126665_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 384.0
HKD2_k127_3126665_8 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 347.0
HKD2_k127_3126665_9 DMT superfamily K11939 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002413 286.0
HKD2_k127_316075_0 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
HKD2_k127_316075_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002609 280.0
HKD2_k127_316075_2 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000246 211.0
HKD2_k127_316075_3 Amino-transferase class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000007475 177.0
HKD2_k127_316075_4 Pfam:DUF59 - - - 0.0000000000114 72.0
HKD2_k127_316075_5 Protein of unknown function (DUF433) - - - 0.0006584 46.0
HKD2_k127_3244646_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 2.658e-249 797.0
HKD2_k127_3244646_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 478.0
HKD2_k127_3244646_2 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 401.0
HKD2_k127_3244646_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000007535 164.0
HKD2_k127_3244646_4 Transmembrane secretion effector - - - 0.000000000000000000000000000001464 139.0
HKD2_k127_3244646_5 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000001321 125.0
HKD2_k127_3244646_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000003129 123.0
HKD2_k127_3244646_7 Mechanosensitive ion channel - - - 0.00000002282 67.0
HKD2_k127_3255679_0 FeS assembly protein SufB K09014 - - 3.339e-212 668.0
HKD2_k127_3255679_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 350.0
HKD2_k127_3255679_10 Phosphotriesterase family K07048 - - 0.0000000001439 63.0
HKD2_k127_3255679_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001139 246.0
HKD2_k127_3255679_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002949 221.0
HKD2_k127_3255679_4 response regulator K02479 - - 0.00000000000000000000000000000000000000000000000000001324 211.0
HKD2_k127_3255679_5 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000005861 168.0
HKD2_k127_3255679_6 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000001553 148.0
HKD2_k127_3255679_7 pfam nudix - - - 0.0000000000000000000000000000000000596 143.0
HKD2_k127_3255679_8 membrane - - - 0.000000000000000000000566 104.0
HKD2_k127_3255679_9 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000103 75.0
HKD2_k127_332984_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.567e-264 824.0
HKD2_k127_332984_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 556.0
HKD2_k127_332984_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 421.0
HKD2_k127_332984_3 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 403.0
HKD2_k127_332984_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000003822 243.0
HKD2_k127_332984_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000004592 155.0
HKD2_k127_332984_6 TIGRFAM Flp pilus assembly protein CpaB K02279 - - 0.000495 51.0
HKD2_k127_3400429_0 CobB/CobQ-like glutamine amidotransferase domain K07009 - - 0.0000000000000000000000000000000000000000000000001909 190.0
HKD2_k127_3400429_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000002352 194.0
HKD2_k127_3400429_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000004689 177.0
HKD2_k127_3400429_3 Domain of unknown function (DUF1727) - - - 0.000000000000000000000000000000000000000183 159.0
HKD2_k127_3400429_4 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000004964 164.0
HKD2_k127_3400429_5 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000002568 134.0
HKD2_k127_3818693_0 GMC oxidoreductase K00108 - 1.1.99.1 4.03e-268 840.0
HKD2_k127_3818693_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 308.0
HKD2_k127_3818693_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006571 281.0
HKD2_k127_3818693_3 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000007313 243.0
HKD2_k127_3818693_4 ApbE family - - - 0.00000000000000000000000000000000000000000000000000000000000002652 223.0
HKD2_k127_3818693_5 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000002147 232.0
HKD2_k127_3818693_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000001461 199.0
HKD2_k127_3818693_7 typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000002007 182.0
HKD2_k127_3818693_8 PFAM ATP-binding region ATPase domain protein, histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000005527 183.0
HKD2_k127_3818693_9 HlyD family secretion protein K02005,K13888 - - 0.00000000000000000000000002516 123.0
HKD2_k127_3830650_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 357.0
HKD2_k127_3830650_1 recombinase XerD K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007448 264.0
HKD2_k127_3830650_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000002258 109.0
HKD2_k127_3830650_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000001391 110.0
HKD2_k127_3830650_12 PFAM HD domain - - - 0.0000004668 61.0
HKD2_k127_3830650_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005873 265.0
HKD2_k127_3830650_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000006783 246.0
HKD2_k127_3830650_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000006443 215.0
HKD2_k127_3830650_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000003092 216.0
HKD2_k127_3830650_6 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000003516 183.0
HKD2_k127_3830650_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000001588 155.0
HKD2_k127_3830650_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000151 146.0
HKD2_k127_3830650_9 PFAM membrane-flanked domain - - - 0.0000000000000000000000003429 124.0
HKD2_k127_3837499_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 371.0
HKD2_k127_3837499_1 teichoic acid biosynthesis protein B K18704 - 2.7.8.14,2.7.8.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 308.0
HKD2_k127_3837499_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002679 249.0
HKD2_k127_3837499_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000002725 70.0
HKD2_k127_3837499_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K13015 - 1.1.1.136,1.1.1.336 0.000002131 59.0
HKD2_k127_3837499_7 glycosyl transferase K00721 - 2.4.1.83 0.00004927 56.0
HKD2_k127_3837499_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0007328 53.0
HKD2_k127_3846762_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 586.0
HKD2_k127_3846762_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 570.0
HKD2_k127_3846762_10 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000005595 168.0
HKD2_k127_3846762_11 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000009771 159.0
HKD2_k127_3846762_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000002213 162.0
HKD2_k127_3846762_13 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000003874 167.0
HKD2_k127_3846762_14 glyoxalase III activity - - - 0.000000000001172 77.0
HKD2_k127_3846762_15 PFAM alpha beta hydrolase fold - - - 0.000000000002017 76.0
HKD2_k127_3846762_16 PucR C-terminal helix-turn-helix domain - - - 0.0000000003589 72.0
HKD2_k127_3846762_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000187 66.0
HKD2_k127_3846762_19 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000579 59.0
HKD2_k127_3846762_2 COG COG0531 Amino acid transporters Amino acid transport and metabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 450.0
HKD2_k127_3846762_20 - - - - 0.00002578 47.0
HKD2_k127_3846762_21 - - - - 0.0004789 52.0
HKD2_k127_3846762_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 384.0
HKD2_k127_3846762_4 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 368.0
HKD2_k127_3846762_5 Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 306.0
HKD2_k127_3846762_6 Ion channel - - - 0.000000000000000000000000000000000000000000000000000002458 206.0
HKD2_k127_3846762_7 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000001522 193.0
HKD2_k127_3846762_8 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000003628 177.0
HKD2_k127_3846762_9 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000488 172.0
HKD2_k127_3878589_0 FAD dependent oxidoreductase central domain - - - 0.0 1106.0
HKD2_k127_3878589_1 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 596.0
HKD2_k127_3878589_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001634 243.0
HKD2_k127_3878589_11 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 247.0
HKD2_k127_3878589_12 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000001212 237.0
HKD2_k127_3878589_13 - - - - 0.0000000000000000000000000000000000000000000000004162 183.0
HKD2_k127_3878589_14 - - - - 0.000000000000000000000000000000000000000000000001561 189.0
HKD2_k127_3878589_15 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000000000006979 175.0
HKD2_k127_3878589_16 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000007063 174.0
HKD2_k127_3878589_17 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000902 158.0
HKD2_k127_3878589_18 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000002883 146.0
HKD2_k127_3878589_19 Domain of unknown function (DUF4260) - - - 0.0000000000000000000000000005079 119.0
HKD2_k127_3878589_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 505.0
HKD2_k127_3878589_20 Pfam:DUF59 - - - 0.00003241 48.0
HKD2_k127_3878589_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 482.0
HKD2_k127_3878589_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 449.0
HKD2_k127_3878589_5 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 449.0
HKD2_k127_3878589_6 metallophosphoesterase K07096,K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 374.0
HKD2_k127_3878589_7 PFAM binding-protein-dependent transport systems inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 342.0
HKD2_k127_3878589_8 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 359.0
HKD2_k127_3878589_9 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001897 284.0
HKD2_k127_3878655_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 589.0
HKD2_k127_3878655_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 394.0
HKD2_k127_3878655_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006536 284.0
HKD2_k127_3878655_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000242 227.0
HKD2_k127_3878655_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000002818 203.0
HKD2_k127_3878655_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000007139 90.0
HKD2_k127_3878655_6 spore germination K03605 - - 0.0000000000009393 81.0
HKD2_k127_3878655_7 HupF/HypC family K04653 - - 0.00000000006553 72.0
HKD2_k127_3943047_0 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 453.0
HKD2_k127_3943047_1 Bacterial extracellular solute-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 435.0
HKD2_k127_3943047_10 DNA-binding protein K06204 - - 0.000000000004327 78.0
HKD2_k127_3943047_2 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 419.0
HKD2_k127_3943047_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 346.0
HKD2_k127_3943047_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 316.0
HKD2_k127_3943047_5 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 324.0
HKD2_k127_3943047_6 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009472 285.0
HKD2_k127_3943047_7 Cytochrome c oxidase K02351,K07245 - - 0.0000000000000000000000000000000000000000003946 173.0
HKD2_k127_3943047_8 4Fe-4S binding domain - - - 0.000000000000000000000000002761 122.0
HKD2_k127_3943047_9 RDD family - - - 0.000000000000000004832 91.0
HKD2_k127_3986497_0 aminopeptidase N - - - 0.00000000000000000000000000000000000006951 163.0
HKD2_k127_3986497_1 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000006114 128.0
HKD2_k127_3986497_2 Glycosyl hydrolases family 18 - - - 0.000000000000000003107 98.0
HKD2_k127_3986497_3 Protein of unknown function (DUF4236) - - - 0.000000000000006963 87.0
HKD2_k127_3986497_4 PFAM blue (type 1) copper domain protein - - - 0.0000004814 61.0
HKD2_k127_3986497_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000001415 61.0
HKD2_k127_4026940_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 460.0
HKD2_k127_4026940_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 341.0
HKD2_k127_4026940_2 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000003286 243.0
HKD2_k127_4026940_3 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000005643 213.0
HKD2_k127_4026940_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000001196 129.0
HKD2_k127_4219057_0 PFAM Adenosine AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 490.0
HKD2_k127_4219057_1 Catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 390.0
HKD2_k127_4219057_2 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003293 285.0
HKD2_k127_4219057_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000006176 184.0
HKD2_k127_4219057_4 integral membrane protein - - - 0.0000000005085 66.0
HKD2_k127_4219057_5 helix_turn_helix, Lux Regulon - - - 0.0000000005304 61.0
HKD2_k127_4344926_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 611.0
HKD2_k127_4344926_1 Dihydrolipoamide K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 459.0
HKD2_k127_4344926_10 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000004539 190.0
HKD2_k127_4344926_11 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000002607 131.0
HKD2_k127_4344926_13 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000001509 121.0
HKD2_k127_4344926_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000001216 126.0
HKD2_k127_4344926_15 e3 binding domain K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000406 109.0
HKD2_k127_4344926_16 Serine aminopeptidase, S33 - - - 0.00000000000000000000000009604 120.0
HKD2_k127_4344926_17 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000004823 114.0
HKD2_k127_4344926_18 ECF sigma factor K03088 - - 0.0000000000000000000001837 104.0
HKD2_k127_4344926_19 Glutamyl-tRNAGlu reductase, N-terminal domain K02492 GO:0008150,GO:0040007 1.2.1.70 0.00000000000000000005772 107.0
HKD2_k127_4344926_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 440.0
HKD2_k127_4344926_3 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 388.0
HKD2_k127_4344926_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 394.0
HKD2_k127_4344926_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 360.0
HKD2_k127_4344926_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 356.0
HKD2_k127_4344926_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000007886 233.0
HKD2_k127_4344926_8 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000005233 216.0
HKD2_k127_4344926_9 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000001291 195.0
HKD2_k127_4381267_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 8.15e-253 818.0
HKD2_k127_4381267_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 454.0
HKD2_k127_4381267_2 ABC transporter substrate-binding protein K10232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 392.0
HKD2_k127_4381267_3 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000005472 87.0
HKD2_k127_4381267_4 response regulator - - - 0.00000000000006769 73.0
HKD2_k127_4381267_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000001924 76.0
HKD2_k127_4411756_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 587.0
HKD2_k127_4411756_1 malic protein domain protein K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 586.0
HKD2_k127_4411756_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 328.0
HKD2_k127_4411756_11 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 269.0
HKD2_k127_4411756_12 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000002766 270.0
HKD2_k127_4411756_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000231 242.0
HKD2_k127_4411756_14 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000000000000000000004711 206.0
HKD2_k127_4411756_15 - - - - 0.000000000000000000000000000000000000000000000000000356 203.0
HKD2_k127_4411756_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000001017 205.0
HKD2_k127_4411756_17 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000001642 173.0
HKD2_k127_4411756_19 PFAM NUDIX domain - - - 0.00000000000000000000000000000003998 143.0
HKD2_k127_4411756_2 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 492.0
HKD2_k127_4411756_20 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000001428 131.0
HKD2_k127_4411756_21 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000009083 101.0
HKD2_k127_4411756_22 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000004608 74.0
HKD2_k127_4411756_3 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 374.0
HKD2_k127_4411756_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 348.0
HKD2_k127_4411756_5 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 355.0
HKD2_k127_4411756_6 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 352.0
HKD2_k127_4411756_7 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 352.0
HKD2_k127_4411756_8 PFAM TrkA-N domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
HKD2_k127_4411756_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 323.0
HKD2_k127_4616358_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 459.0
HKD2_k127_4616358_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 394.0
HKD2_k127_4616358_2 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000119 287.0
HKD2_k127_4616358_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 269.0
HKD2_k127_4616358_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000001708 194.0
HKD2_k127_4616358_5 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000001976 183.0
HKD2_k127_4616358_6 DNA ligase K01971 - 6.5.1.1 0.0000006057 59.0
HKD2_k127_4695097_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 433.0
HKD2_k127_4695097_1 Cell cycle protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 350.0
HKD2_k127_4695097_10 FHA domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000004271 111.0
HKD2_k127_4695097_11 phosphoglycerate mutase family K22305 - 3.1.3.3 0.000000000000000000006346 108.0
HKD2_k127_4695097_12 ABC transporter substrate-binding protein K10232 - - 0.00000000007246 66.0
HKD2_k127_4695097_13 helix_turn_helix, Lux Regulon - - - 0.00005475 52.0
HKD2_k127_4695097_14 Double zinc ribbon - - - 0.0001065 53.0
HKD2_k127_4695097_2 Aminotransferase class-V K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 325.0
HKD2_k127_4695097_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008646 293.0
HKD2_k127_4695097_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000502 238.0
HKD2_k127_4695097_5 Cell division protein FtsI penicillin-binding protein K05364 - - 0.00000000000000000000000000000000000000000000000000000000000000007755 252.0
HKD2_k127_4695097_6 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001295 216.0
HKD2_k127_4695097_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000009167 218.0
HKD2_k127_4695097_8 PFAM Forkhead-associated protein - - - 0.00000000000000000000000003634 115.0
HKD2_k127_4695097_9 COG1305 Transglutaminase-like enzymes - - - 0.0000000000000000000000009303 121.0
HKD2_k127_479215_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.073e-244 777.0
HKD2_k127_479215_1 associated with various cellular activities K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 547.0
HKD2_k127_479215_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000001181 201.0
HKD2_k127_479215_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000008135 139.0
HKD2_k127_479215_12 Putative bacterial sensory transduction regulator - - - 0.0000000001485 73.0
HKD2_k127_479215_13 Putative bacterial sensory transduction regulator - - - 0.000000000367 73.0
HKD2_k127_479215_16 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.0005937 52.0
HKD2_k127_479215_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 514.0
HKD2_k127_479215_3 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 441.0
HKD2_k127_479215_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 335.0
HKD2_k127_479215_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 331.0
HKD2_k127_479215_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 308.0
HKD2_k127_479215_7 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001101 309.0
HKD2_k127_479215_8 DRTGG domain K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009538 260.0
HKD2_k127_479215_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000009836 201.0
HKD2_k127_4826376_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 553.0
HKD2_k127_4826376_1 COG COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit Energy production and conversion K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 440.0
HKD2_k127_4826376_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000008589 275.0
HKD2_k127_4826376_3 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000002926 229.0
HKD2_k127_4826376_4 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000141 184.0
HKD2_k127_4826376_5 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000004226 164.0
HKD2_k127_4826376_6 Sporulation and spore germination - - - 0.000000000000000000000000000000000000002636 161.0
HKD2_k127_485476_0 Heat shock 70 kDa protein K04043 - - 2.546e-255 809.0
HKD2_k127_485476_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 462.0
HKD2_k127_485476_2 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 419.0
HKD2_k127_485476_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005207 261.0
HKD2_k127_485476_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
HKD2_k127_485476_5 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000003503 245.0
HKD2_k127_485476_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000001222 136.0
HKD2_k127_485476_7 CAAX protease self-immunity K07052 - - 0.00004345 54.0
HKD2_k127_4966447_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 467.0
HKD2_k127_4966447_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 465.0
HKD2_k127_4966447_2 PFAM AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 317.0
HKD2_k127_4966447_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
HKD2_k127_4966447_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.000000000000000000000000000000000000000000000000003062 185.0
HKD2_k127_4966447_5 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000001162 187.0
HKD2_k127_4966447_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000339 151.0
HKD2_k127_4966447_7 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000006223 93.0
HKD2_k127_4966447_8 Methyltransferase domain - - - 0.0000001665 58.0
HKD2_k127_5131589_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.215e-241 756.0
HKD2_k127_5131589_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 2.894e-214 691.0
HKD2_k127_5131589_2 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 430.0
HKD2_k127_5131589_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001825 266.0
HKD2_k127_5131589_4 DinB superfamily - - - 0.000000000000000000000000000000000000000008661 160.0
HKD2_k127_5131589_5 Translation initiation inhibitor K09022 - 3.5.99.10 0.000000000000000000000000000000000000006574 149.0
HKD2_k127_5131589_6 glyoxalase III activity - - - 0.0000000000000000000000000000001438 134.0
HKD2_k127_5131589_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000001818 103.0
HKD2_k127_5142737_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 508.0
HKD2_k127_5142737_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 428.0
HKD2_k127_5142737_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 393.0
HKD2_k127_5142737_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 310.0
HKD2_k127_5142737_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
HKD2_k127_5142737_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002682 291.0
HKD2_k127_5142737_6 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006729 263.0
HKD2_k127_5142737_7 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000001615 229.0
HKD2_k127_5142737_8 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000001177 141.0
HKD2_k127_5289232_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 2.473e-281 892.0
HKD2_k127_5289232_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 8.969e-243 758.0
HKD2_k127_5289232_10 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 320.0
HKD2_k127_5289232_11 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 310.0
HKD2_k127_5289232_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 293.0
HKD2_k127_5289232_13 Sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
HKD2_k127_5289232_14 - - - - 0.000000000000000000000000000000000000000000000000005386 193.0
HKD2_k127_5289232_15 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000001885 185.0
HKD2_k127_5289232_16 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000005391 177.0
HKD2_k127_5289232_17 Dihydroorotate dehydrogenase - - - 0.000000000000000000000001934 112.0
HKD2_k127_5289232_19 Phage shock protein C, PspC K03973 - - 0.00000000000002491 80.0
HKD2_k127_5289232_2 Pyridoxal-phosphate dependent enzyme - - - 3.432e-206 655.0
HKD2_k127_5289232_20 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000001761 82.0
HKD2_k127_5289232_21 Biotin-requiring enzyme - - - 0.0000000003053 72.0
HKD2_k127_5289232_22 membrane - - - 0.00000000116 70.0
HKD2_k127_5289232_3 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 562.0
HKD2_k127_5289232_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 494.0
HKD2_k127_5289232_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 474.0
HKD2_k127_5289232_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 465.0
HKD2_k127_5289232_7 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 450.0
HKD2_k127_5289232_8 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 423.0
HKD2_k127_5289232_9 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 364.0
HKD2_k127_5385398_0 Aminotransferase class-V - - - 6.493e-242 778.0
HKD2_k127_5385398_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 530.0
HKD2_k127_5385398_10 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000005694 133.0
HKD2_k127_5385398_11 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000001538 140.0
HKD2_k127_5385398_12 Ferredoxin - - - 0.00000000000000000001395 95.0
HKD2_k127_5385398_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 519.0
HKD2_k127_5385398_3 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 377.0
HKD2_k127_5385398_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
HKD2_k127_5385398_5 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000006984 215.0
HKD2_k127_5385398_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001352 208.0
HKD2_k127_5385398_7 protein histidine kinase activity - - - 0.000000000000000000000000000000000000008091 162.0
HKD2_k127_5385398_8 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000004829 144.0
HKD2_k127_5385398_9 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000003385 149.0
HKD2_k127_5475471_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 597.0
HKD2_k127_5475471_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 546.0
HKD2_k127_5475471_2 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 462.0
HKD2_k127_5475471_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 339.0
HKD2_k127_5475471_4 transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000002181 175.0
HKD2_k127_5475471_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000005151 153.0
HKD2_k127_5475471_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000741 114.0
HKD2_k127_5475471_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000004767 97.0
HKD2_k127_5475471_8 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000002249 88.0
HKD2_k127_5475471_9 helix_turn_helix, Arsenical Resistance Operon Repressor K22298 - - 0.00000000005502 68.0
HKD2_k127_5483002_0 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 508.0
HKD2_k127_5483002_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 393.0
HKD2_k127_5483002_10 Rieske-like [2Fe-2S] domain K15762 - - 0.00000000003493 72.0
HKD2_k127_5483002_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000269 69.0
HKD2_k127_5483002_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 319.0
HKD2_k127_5483002_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 314.0
HKD2_k127_5483002_4 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000008711 224.0
HKD2_k127_5483002_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000001147 186.0
HKD2_k127_5483002_6 acetyltransferase - - - 0.00000000000000000000000000000000001552 149.0
HKD2_k127_5483002_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000002953 141.0
HKD2_k127_5483002_8 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000001877 135.0
HKD2_k127_5483002_9 Uncharacterized protein family (UPF0051) K09015 GO:0008150,GO:0009605,GO:0009607,GO:0040007,GO:0043207,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0075136 - 0.000000000000000000004393 96.0
HKD2_k127_549361_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000002629 195.0
HKD2_k127_549361_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000002574 147.0
HKD2_k127_549361_3 Domain of unknown function (DUF2437) - - - 0.00000000000000007526 87.0
HKD2_k127_549361_4 Bacterial regulatory proteins, tetR family - - - 0.000000000003026 75.0
HKD2_k127_5562157_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 474.0
HKD2_k127_5562157_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 428.0
HKD2_k127_5562157_2 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 389.0
HKD2_k127_5562157_3 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 362.0
HKD2_k127_5562157_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000001702 132.0
HKD2_k127_5562157_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000006831 96.0
HKD2_k127_5562157_6 Endoribonuclease that initiates mRNA decay K18682 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000001572 102.0
HKD2_k127_5562157_7 Modulates RecA activity K03565 - - 0.00000000000000005353 90.0
HKD2_k127_5578817_0 Evidence 5 No homology to any previously reported sequences - - - 1.673e-271 861.0
HKD2_k127_5578817_1 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 505.0
HKD2_k127_5578817_10 protein with SCP PR1 domains - - - 0.000000000000004197 84.0
HKD2_k127_5578817_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 471.0
HKD2_k127_5578817_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 446.0
HKD2_k127_5578817_4 cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 380.0
HKD2_k127_5578817_5 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001802 280.0
HKD2_k127_5578817_6 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000001878 226.0
HKD2_k127_5578817_7 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000006146 183.0
HKD2_k127_5578817_8 oxidoreductase activity K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000001664 156.0
HKD2_k127_5578817_9 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000005215 128.0
HKD2_k127_5586239_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.828e-196 625.0
HKD2_k127_5586239_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 557.0
HKD2_k127_5586239_10 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000115 216.0
HKD2_k127_5586239_11 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000000000001662 209.0
HKD2_k127_5586239_12 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000003257 199.0
HKD2_k127_5586239_13 MgtC family K07507 - - 0.000000000000000000000000000000000009367 145.0
HKD2_k127_5586239_14 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000000000001135 119.0
HKD2_k127_5586239_15 Protein of unknown function (DUF1003) - - - 0.000000000000000003503 96.0
HKD2_k127_5586239_2 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 433.0
HKD2_k127_5586239_3 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 423.0
HKD2_k127_5586239_4 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 326.0
HKD2_k127_5586239_5 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 310.0
HKD2_k127_5586239_6 ABC-type multidrug transport system ATPase component K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003096 291.0
HKD2_k127_5586239_7 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006307 260.0
HKD2_k127_5586239_8 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000004985 242.0
HKD2_k127_5586239_9 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001034 233.0
HKD2_k127_5595520_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 484.0
HKD2_k127_5595520_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 466.0
HKD2_k127_5595520_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
HKD2_k127_5595520_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005275 291.0
HKD2_k127_5595520_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002267 288.0
HKD2_k127_5595520_5 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000672 239.0
HKD2_k127_5595520_6 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000001326 217.0
HKD2_k127_5595520_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000001292 83.0
HKD2_k127_56618_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 317.0
HKD2_k127_56618_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 295.0
HKD2_k127_56618_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 298.0
HKD2_k127_56618_3 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000002317 123.0
HKD2_k127_56618_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000001037 97.0
HKD2_k127_56618_5 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000005808 94.0
HKD2_k127_56618_6 Ribosomal protein L34 K02914 - - 0.000000000009055 66.0
HKD2_k127_56618_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000005379 68.0
HKD2_k127_56618_8 Domain of unknown function (DU1801) - - - 0.00000002069 68.0
HKD2_k127_56618_9 Helix-turn-helix XRE-family like proteins - - - 0.000000527 62.0
HKD2_k127_5701460_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 475.0
HKD2_k127_5701460_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 305.0
HKD2_k127_5701460_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 273.0
HKD2_k127_5701460_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000002372 199.0
HKD2_k127_5701460_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000118 173.0
HKD2_k127_5701460_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001844 101.0
HKD2_k127_5701460_6 Activator of hsp90 atpase 1 family protein - - - 0.00000000000008681 78.0
HKD2_k127_5701460_7 MscS Mechanosensitive ion channel - - - 0.000000000491 71.0
HKD2_k127_5842754_0 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 584.0
HKD2_k127_5842754_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 334.0
HKD2_k127_5842754_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 327.0
HKD2_k127_5842754_3 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001718 263.0
HKD2_k127_5842754_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000158 243.0
HKD2_k127_5983277_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 335.0
HKD2_k127_5983277_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 312.0
HKD2_k127_5983277_10 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000004577 101.0
HKD2_k127_5983277_11 NYN domain - - - 0.000000000000000000001476 109.0
HKD2_k127_5983277_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000009223 96.0
HKD2_k127_5983277_13 NHL repeat - - - 0.0000000000000005241 91.0
HKD2_k127_5983277_14 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.0000000000005507 81.0
HKD2_k127_5983277_15 amino acid-binding ACT domain protein - - - 0.00001301 54.0
HKD2_k127_5983277_16 - - - - 0.0006055 49.0
HKD2_k127_5983277_2 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003046 293.0
HKD2_k127_5983277_3 Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000001168 246.0
HKD2_k127_5983277_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000002135 168.0
HKD2_k127_5983277_5 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000001315 146.0
HKD2_k127_5983277_6 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000001411 141.0
HKD2_k127_5983277_7 Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - 0.0000000000000000000000000000001525 141.0
HKD2_k127_5983277_8 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000006549 130.0
HKD2_k127_5983277_9 amino acid activation for nonribosomal peptide biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000002282 132.0
HKD2_k127_600455_0 Flavin containing amine oxidoreductase - - - 4.087e-232 729.0
HKD2_k127_600455_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 531.0
HKD2_k127_600455_10 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000008108 121.0
HKD2_k127_600455_11 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000003708 122.0
HKD2_k127_600455_12 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000001353 117.0
HKD2_k127_600455_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031967,GO:0031975,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 - 0.00000000000000000000004276 106.0
HKD2_k127_600455_14 AI-2E family transporter K03548 - - 0.000000000000000000001537 108.0
HKD2_k127_600455_15 VIT family - - - 0.000001107 63.0
HKD2_k127_600455_16 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000001324 58.0
HKD2_k127_600455_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 447.0
HKD2_k127_600455_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 410.0
HKD2_k127_600455_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 361.0
HKD2_k127_600455_5 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 337.0
HKD2_k127_600455_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 311.0
HKD2_k127_600455_7 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
HKD2_k127_600455_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000002361 225.0
HKD2_k127_600455_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000006064 162.0
HKD2_k127_6015392_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 563.0
HKD2_k127_6015392_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 373.0
HKD2_k127_6015392_10 - - - - 0.00000000000006263 83.0
HKD2_k127_6015392_2 Acetyltransferase (GNAT) domain K00657,K00663 - 2.3.1.57,2.3.1.82 0.000000000000000000000000000000000000000000000000000006749 197.0
HKD2_k127_6015392_3 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000008073 175.0
HKD2_k127_6015392_4 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000006354 182.0
HKD2_k127_6015392_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000704 173.0
HKD2_k127_6015392_6 nitrite reductase [NAD(P)H] activity K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000001732 179.0
HKD2_k127_6015392_7 YCII-related domain - - - 0.00000000000000000000000000002782 124.0
HKD2_k127_6015392_8 OsmC-like protein - - - 0.0000000000000000000000000004797 120.0
HKD2_k127_6015392_9 FR47-like protein - - - 0.0000000000000000000001366 108.0
HKD2_k127_6390221_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 531.0
HKD2_k127_6390221_1 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 480.0
HKD2_k127_6390221_10 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000000000000000000341 160.0
HKD2_k127_6390221_11 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000009981 151.0
HKD2_k127_6390221_12 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000005098 145.0
HKD2_k127_6390221_13 PFAM Cobalt transport protein K16785 - - 0.00000000000000000000000000001741 128.0
HKD2_k127_6390221_14 - - - - 0.0000000000000000000000005575 112.0
HKD2_k127_6390221_15 Universal stress protein family - - - 0.00000000000000002238 93.0
HKD2_k127_6390221_16 Mov34 MPN PAD-1 family K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000002618 89.0
HKD2_k127_6390221_17 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0001279 56.0
HKD2_k127_6390221_2 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 398.0
HKD2_k127_6390221_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 402.0
HKD2_k127_6390221_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 390.0
HKD2_k127_6390221_5 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 302.0
HKD2_k127_6390221_6 Cysteine synthase K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005486 296.0
HKD2_k127_6390221_7 PFAM ABC transporter related K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007819 299.0
HKD2_k127_6390221_8 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001087 284.0
HKD2_k127_6390221_9 - - - - 0.0000000000000000000000000000000000000000005761 162.0
HKD2_k127_6390326_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 479.0
HKD2_k127_6390326_1 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 430.0
HKD2_k127_6390326_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000001899 108.0
HKD2_k127_6390326_11 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000001916 108.0
HKD2_k127_6390326_12 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000004869 116.0
HKD2_k127_6390326_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000004842 93.0
HKD2_k127_6390326_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000001203 86.0
HKD2_k127_6390326_15 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000003968 79.0
HKD2_k127_6390326_17 Ribosomal L28 family K02902 - - 0.00001135 57.0
HKD2_k127_6390326_18 protein conserved in bacteria - - - 0.0006012 50.0
HKD2_k127_6390326_2 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 354.0
HKD2_k127_6390326_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 327.0
HKD2_k127_6390326_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 291.0
HKD2_k127_6390326_5 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000255 223.0
HKD2_k127_6390326_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000005901 196.0
HKD2_k127_6390326_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000001905 171.0
HKD2_k127_6390326_8 Ribonuclease III family K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000004127 168.0
HKD2_k127_6390326_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000005336 169.0
HKD2_k127_6411268_0 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 441.0
HKD2_k127_6411268_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 381.0
HKD2_k127_6411268_11 amine dehydrogenase activity - - - 0.0001696 54.0
HKD2_k127_6411268_2 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 332.0
HKD2_k127_6411268_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000001094 177.0
HKD2_k127_6411268_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000002234 155.0
HKD2_k127_6411268_5 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000003169 123.0
HKD2_k127_6411268_6 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000002873 95.0
HKD2_k127_6411268_7 SAM-dependent methyltransferase - - - 0.0000000009277 68.0
HKD2_k127_6411268_8 Hemerythrin HHE cation binding domain - - - 0.000000001003 68.0
HKD2_k127_6428167_0 AAA domain - - - 1.696e-241 783.0
HKD2_k127_6428167_1 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 3.876e-201 640.0
HKD2_k127_6428167_10 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 290.0
HKD2_k127_6428167_11 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000008634 184.0
HKD2_k127_6428167_12 Domain of unknown function DUF302 - - - 0.00000000000000000000000000005564 135.0
HKD2_k127_6428167_13 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000001662 125.0
HKD2_k127_6428167_14 - - - - 0.0000000000000000000000008727 108.0
HKD2_k127_6428167_15 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000001982 75.0
HKD2_k127_6428167_16 PFAM Cytochrome c, bacterial - - - 0.0001453 53.0
HKD2_k127_6428167_2 Dihydropyrimidinase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 588.0
HKD2_k127_6428167_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 550.0
HKD2_k127_6428167_4 catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 513.0
HKD2_k127_6428167_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 488.0
HKD2_k127_6428167_6 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 439.0
HKD2_k127_6428167_7 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 412.0
HKD2_k127_6428167_8 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 378.0
HKD2_k127_6428167_9 Glutamate synthase K17722 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 361.0
HKD2_k127_6486328_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.172e-206 674.0
HKD2_k127_6486328_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000006914 220.0
HKD2_k127_6486328_2 DinB family - - - 0.0000000000000000000000000000000000000347 149.0
HKD2_k127_6486328_3 EamA-like transporter family - - - 0.0000000002211 72.0
HKD2_k127_6486328_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000001463 60.0
HKD2_k127_6641416_0 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 572.0
HKD2_k127_6641416_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 464.0
HKD2_k127_6641416_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.0000000000000000000009853 101.0
HKD2_k127_6641416_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 0.00003979 53.0
HKD2_k127_6641416_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 444.0
HKD2_k127_6641416_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 385.0
HKD2_k127_6641416_4 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 331.0
HKD2_k127_6641416_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002405 289.0
HKD2_k127_6641416_6 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000003075 226.0
HKD2_k127_6641416_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000595 193.0
HKD2_k127_6641416_8 ABC-type cobalt transport system, permease component K16925 - - 0.0000000000000000000000000000000000000004665 158.0
HKD2_k127_6641416_9 cobalt transport K16785 - - 0.00000000000000000000000000001832 136.0
HKD2_k127_6658968_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 607.0
HKD2_k127_6658968_1 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 443.0
HKD2_k127_6658968_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000001026 244.0
HKD2_k127_6658968_11 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004281 244.0
HKD2_k127_6658968_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
HKD2_k127_6658968_13 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000204 209.0
HKD2_k127_6658968_14 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000004729 200.0
HKD2_k127_6658968_15 - - - - 0.0000000000000000000000000000000000000000000000001513 191.0
HKD2_k127_6658968_16 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.000000000000000000000000000000000000000003078 176.0
HKD2_k127_6658968_17 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000009206 165.0
HKD2_k127_6658968_18 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000002379 170.0
HKD2_k127_6658968_19 Nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000000287 132.0
HKD2_k127_6658968_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 443.0
HKD2_k127_6658968_20 amino acid - - - 0.000000000000000000000000000008288 136.0
HKD2_k127_6658968_21 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000001199 118.0
HKD2_k127_6658968_22 Peptidase MA superfamily - - - 0.0000000000000000000004556 111.0
HKD2_k127_6658968_23 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000004603 88.0
HKD2_k127_6658968_24 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000671 87.0
HKD2_k127_6658968_25 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000006736 85.0
HKD2_k127_6658968_26 Glutaredoxin-like domain (DUF836) - - - 0.000003752 49.0
HKD2_k127_6658968_27 Leucine rich repeat containing 16B K20493 GO:0000902,GO:0000904,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008150,GO:0008361,GO:0009605,GO:0009653,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010769,GO:0010975,GO:0016020,GO:0016043,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023057,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030516,GO:0031175,GO:0031344,GO:0032101,GO:0032501,GO:0032502,GO:0032535,GO:0032794,GO:0032879,GO:0032989,GO:0032990,GO:0035020,GO:0035021,GO:0040008,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0044464,GO:0045595,GO:0045664,GO:0046578,GO:0046580,GO:0048468,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048638,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048841,GO:0048856,GO:0048858,GO:0048869,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0051056,GO:0051058,GO:0051128,GO:0051239,GO:0051270,GO:0051960,GO:0060284,GO:0061387,GO:0061564,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066,GO:0097485,GO:0120035,GO:0120036,GO:0120039,GO:1902531,GO:1902532,GO:1902667,GO:2000026,GO:2000145 - 0.0003034 46.0
HKD2_k127_6658968_3 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 422.0
HKD2_k127_6658968_4 Belongs to the class-I aminoacyl-tRNA synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 421.0
HKD2_k127_6658968_5 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 400.0
HKD2_k127_6658968_6 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 393.0
HKD2_k127_6658968_7 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 325.0
HKD2_k127_6658968_8 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
HKD2_k127_6658968_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004569 277.0
HKD2_k127_6727656_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 390.0
HKD2_k127_6727656_1 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002073 261.0
HKD2_k127_6727656_2 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000001241 253.0
HKD2_k127_6727656_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000006371 154.0
HKD2_k127_6727656_4 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000004303 81.0
HKD2_k127_6727656_5 Negative regulatory protein yxlE - - - 0.0001718 51.0
HKD2_k127_6802320_0 ABC transporter K06147 - - 4.318e-249 784.0
HKD2_k127_6802320_1 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 445.0
HKD2_k127_6802320_10 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000002395 157.0
HKD2_k127_6802320_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000003377 150.0
HKD2_k127_6802320_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000003996 123.0
HKD2_k127_6802320_13 Trypsin-like serine protease - - - 0.0000000000000000000000000005805 124.0
HKD2_k127_6802320_14 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000001624 93.0
HKD2_k127_6802320_15 PFAM OsmC family protein K07397 - - 0.000000000000001858 86.0
HKD2_k127_6802320_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 413.0
HKD2_k127_6802320_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 332.0
HKD2_k127_6802320_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 331.0
HKD2_k127_6802320_5 amine dehydrogenase activity K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001506 276.0
HKD2_k127_6802320_6 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000001318 261.0
HKD2_k127_6802320_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000007508 203.0
HKD2_k127_6802320_8 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000002183 199.0
HKD2_k127_6802320_9 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000001092 151.0
HKD2_k127_6884141_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 3.309e-218 692.0
HKD2_k127_6884141_1 Uncharacterised protein family (UPF0261) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 506.0
HKD2_k127_6884141_10 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000018 124.0
HKD2_k127_6884141_11 EamA-like transporter family - - - 0.0000000000004037 81.0
HKD2_k127_6884141_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 498.0
HKD2_k127_6884141_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 431.0
HKD2_k127_6884141_4 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 421.0
HKD2_k127_6884141_5 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
HKD2_k127_6884141_6 branched-chain amino acid transmembrane transporter activity K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
HKD2_k127_6884141_8 PFAM regulatory protein GntR HTH K22293 - - 0.0000000000000000000000000000000000000000000000000000000000000000003599 236.0
HKD2_k127_6884141_9 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.000000000000000000000000000000000001686 148.0
HKD2_k127_6897143_0 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 513.0
HKD2_k127_6897143_1 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 491.0
HKD2_k127_6897143_10 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000248 291.0
HKD2_k127_6897143_11 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003447 224.0
HKD2_k127_6897143_12 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000002137 211.0
HKD2_k127_6897143_13 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000002166 178.0
HKD2_k127_6897143_14 spore germination - - - 0.0000000000000000000000000000000000000001995 165.0
HKD2_k127_6897143_15 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000005266 156.0
HKD2_k127_6897143_16 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000002324 154.0
HKD2_k127_6897143_17 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.0000000000000000000000000000000004188 143.0
HKD2_k127_6897143_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000002294 130.0
HKD2_k127_6897143_19 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000002817 139.0
HKD2_k127_6897143_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 466.0
HKD2_k127_6897143_20 Protein of unknown function (DUF3105) - - - 0.00000000000000001563 94.0
HKD2_k127_6897143_21 - - - - 0.000000000000257 81.0
HKD2_k127_6897143_3 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 471.0
HKD2_k127_6897143_4 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 422.0
HKD2_k127_6897143_5 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 386.0
HKD2_k127_6897143_6 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 343.0
HKD2_k127_6897143_7 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 339.0
HKD2_k127_6897143_8 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 306.0
HKD2_k127_6897143_9 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009318 284.0
HKD2_k127_7002253_0 Protein of unknown function, DUF255 K06888 - - 3.69e-219 700.0
HKD2_k127_7002253_1 DNA polymerase LigD, polymerase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 524.0
HKD2_k127_7002253_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 364.0
HKD2_k127_7002253_3 PFAM luciferase-like - - - 0.0000000000000000000000000000000000000004302 160.0
HKD2_k127_7002253_4 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000002087 151.0
HKD2_k127_7002253_5 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000009219 140.0
HKD2_k127_7002253_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000000000000000000009067 98.0
HKD2_k127_7037469_0 DEAD/H associated K03724 - - 0.0 1489.0
HKD2_k127_7037469_1 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1140.0
HKD2_k127_7037469_10 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000009783 139.0
HKD2_k127_7037469_11 L-valine transmembrane transporter activity - - - 0.000000000000000000000000000006936 130.0
HKD2_k127_7037469_12 NUDIX hydrolase - - - 0.000000000000000000000000001313 125.0
HKD2_k127_7037469_13 FR47-like protein - - - 0.00000152 50.0
HKD2_k127_7037469_2 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 357.0
HKD2_k127_7037469_3 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 335.0
HKD2_k127_7037469_4 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 314.0
HKD2_k127_7037469_5 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000003881 270.0
HKD2_k127_7037469_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000007083 242.0
HKD2_k127_7037469_7 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
HKD2_k127_7037469_8 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000006324 216.0
HKD2_k127_7037469_9 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000006326 171.0
HKD2_k127_7069733_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 599.0
HKD2_k127_7069733_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 442.0
HKD2_k127_7069733_10 cyclic nucleotide binding K01420,K10716 - - 0.0000000000000000000000000000000000000000000000003528 184.0
HKD2_k127_7069733_11 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000001106 182.0
HKD2_k127_7069733_12 beta-lactamase domain protein K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000025 172.0
HKD2_k127_7069733_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000002761 121.0
HKD2_k127_7069733_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000007448 98.0
HKD2_k127_7069733_15 - - - - 0.0000000000000000000445 93.0
HKD2_k127_7069733_16 redox-active disulfide protein 2 - - - 0.000000000000000002539 97.0
HKD2_k127_7069733_17 Major facilitator Superfamily - - - 0.000000000015 78.0
HKD2_k127_7069733_18 Protein of unknown function (DUF2892) - - - 0.00000006699 59.0
HKD2_k127_7069733_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000004248 56.0
HKD2_k127_7069733_2 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 366.0
HKD2_k127_7069733_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 362.0
HKD2_k127_7069733_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 319.0
HKD2_k127_7069733_5 NAD binding domain of 6-phosphogluconate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 316.0
HKD2_k127_7069733_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 302.0
HKD2_k127_7069733_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 291.0
HKD2_k127_7069733_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
HKD2_k127_7069733_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000001365 211.0
HKD2_k127_722459_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 541.0
HKD2_k127_722459_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 473.0
HKD2_k127_722459_10 TIGRFAM cytochrome C family protein - - - 0.00002583 53.0
HKD2_k127_722459_2 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 443.0
HKD2_k127_722459_3 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 305.0
HKD2_k127_722459_4 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000002312 255.0
HKD2_k127_722459_5 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000004162 218.0
HKD2_k127_722459_6 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000003896 214.0
HKD2_k127_722459_7 Response regulator receiver - - - 0.000000000000000000000000000000000004523 146.0
HKD2_k127_722459_8 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000005684 137.0
HKD2_k127_722459_9 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000001475 89.0
HKD2_k127_7250234_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 452.0
HKD2_k127_7250234_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 373.0
HKD2_k127_7250234_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000001461 122.0
HKD2_k127_7250234_11 SCO1 SenC K07152 - - 0.000000000000000000000000003836 127.0
HKD2_k127_7250234_12 Zincin-like metallopeptidase - - - 0.00000000000000000000000001085 114.0
HKD2_k127_7250234_13 Copper chaperone PCu(A)C K07152,K09796 - - 0.000000000000000001261 92.0
HKD2_k127_7250234_14 Transcriptional regulator, arsR family - - - 0.00000000000000002681 88.0
HKD2_k127_7250234_2 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 308.0
HKD2_k127_7250234_3 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 297.0
HKD2_k127_7250234_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001319 287.0
HKD2_k127_7250234_5 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003598 256.0
HKD2_k127_7250234_6 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000002078 257.0
HKD2_k127_7250234_7 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000682 253.0
HKD2_k127_7250234_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000005314 199.0
HKD2_k127_7250234_9 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000009007 188.0
HKD2_k127_7305078_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 3.854e-305 949.0
HKD2_k127_7305078_1 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 486.0
HKD2_k127_7305078_10 cheY-homologous receiver domain - - - 0.0000000000000000000005154 110.0
HKD2_k127_7305078_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 376.0
HKD2_k127_7305078_3 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 372.0
HKD2_k127_7305078_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 359.0
HKD2_k127_7305078_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 314.0
HKD2_k127_7305078_6 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 297.0
HKD2_k127_7305078_7 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000001508 226.0
HKD2_k127_7305078_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000009882 162.0
HKD2_k127_7305078_9 Diguanylate cyclase - - - 0.00000000000000000000000000000001979 147.0
HKD2_k127_7380675_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 455.0
HKD2_k127_7380675_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 299.0
HKD2_k127_7380675_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000004129 210.0
HKD2_k127_7380675_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000001165 177.0
HKD2_k127_7380675_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001056 132.0
HKD2_k127_7380675_5 WD40 repeat, subgroup - - - 0.000000000000000000000000000004524 139.0
HKD2_k127_7380675_6 Protein of unknown function (DUF1634) - - - 0.000000007501 65.0
HKD2_k127_7671729_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 619.0
HKD2_k127_7671729_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 494.0
HKD2_k127_7671729_2 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000329 212.0
HKD2_k127_7671729_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000003626 138.0
HKD2_k127_7671729_4 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000005765 129.0
HKD2_k127_7671729_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000009984 123.0
HKD2_k127_7671729_6 AMP binding - - - 0.0000000000000000000008516 103.0
HKD2_k127_7671729_7 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000006696 97.0
HKD2_k127_7737469_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 613.0
HKD2_k127_7737469_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 604.0
HKD2_k127_7737469_10 PFAM blue (type 1) copper domain protein - - - 0.000000000002642 78.0
HKD2_k127_7737469_12 transcriptional regulator - - - 0.000004939 59.0
HKD2_k127_7737469_13 - - - - 0.0006045 51.0
HKD2_k127_7737469_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 554.0
HKD2_k127_7737469_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000005406 269.0
HKD2_k127_7737469_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000001062 263.0
HKD2_k127_7737469_5 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000001805 219.0
HKD2_k127_7737469_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000274 230.0
HKD2_k127_7737469_7 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000068 186.0
HKD2_k127_7737469_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000005918 123.0
HKD2_k127_7737469_9 Ion channel K10716 - - 0.000000000001523 77.0
HKD2_k127_7738226_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 3.732e-218 693.0
HKD2_k127_7738226_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 2.294e-204 662.0
HKD2_k127_7738226_10 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000366 191.0
HKD2_k127_7738226_11 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000003009 154.0
HKD2_k127_7738226_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000004223 140.0
HKD2_k127_7738226_13 transcriptional regulator - - - 0.0000000000000000000000000000000002541 153.0
HKD2_k127_7738226_15 Helix-turn-helix domain K07729 - - 0.0000000000000000005476 87.0
HKD2_k127_7738226_16 - - - - 0.0000000000001079 76.0
HKD2_k127_7738226_17 F420H(2)-dependent quinone reductase - - - 0.00005403 47.0
HKD2_k127_7738226_2 Belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 599.0
HKD2_k127_7738226_3 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 376.0
HKD2_k127_7738226_4 all-trans-retinol 13,14-reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 291.0
HKD2_k127_7738226_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000163 280.0
HKD2_k127_7738226_6 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000353 252.0
HKD2_k127_7738226_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003024 239.0
HKD2_k127_7738226_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000005624 230.0
HKD2_k127_7738226_9 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000003575 207.0
HKD2_k127_7782412_0 FAD dependent oxidoreductase central domain - - - 2.642e-282 894.0
HKD2_k127_7782412_1 DNA primase, small subunit K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 601.0
HKD2_k127_7782412_10 Ferric uptake regulator family K03711 - - 0.0000000000000000000001746 109.0
HKD2_k127_7782412_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000002648 96.0
HKD2_k127_7782412_12 Major Facilitator Superfamily - - - 0.0000000000000001559 93.0
HKD2_k127_7782412_13 Universal stress protein family - - - 0.00000000000009095 77.0
HKD2_k127_7782412_14 4Fe-4S single cluster domain - - - 0.0000000000001731 74.0
HKD2_k127_7782412_15 - - - - 0.0000002434 62.0
HKD2_k127_7782412_16 - - - - 0.0002636 51.0
HKD2_k127_7782412_2 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 565.0
HKD2_k127_7782412_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008803 284.0
HKD2_k127_7782412_4 ABC 3 transport family K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
HKD2_k127_7782412_5 ATPases associated with a variety of cellular activities K09820 - - 0.0000000000000000000000000000000000000000000000000000000000000001212 232.0
HKD2_k127_7782412_6 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000363 209.0
HKD2_k127_7782412_7 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000008891 196.0
HKD2_k127_7782412_8 VIT family - - - 0.000000000000000000000000000000000000000000000002142 182.0
HKD2_k127_7782412_9 cysteine - - - 0.00000000000000000000000002775 124.0
HKD2_k127_7793528_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
HKD2_k127_7793528_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008169 297.0
HKD2_k127_7793528_2 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001545 246.0
HKD2_k127_7793528_3 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000001198 222.0
HKD2_k127_7793528_4 TIR domain - - - 0.00000000000000000000000000000000008964 152.0
HKD2_k127_7877317_0 Alpha amylase, catalytic domain - - - 2.057e-228 751.0
HKD2_k127_7877317_1 Carbohydrate phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 1.008e-201 651.0
HKD2_k127_7877317_10 ACT domain protein - - - 0.000000000003472 76.0
HKD2_k127_7877317_11 Transcriptional regulator K07979 - - 0.00000005656 64.0
HKD2_k127_7877317_2 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 514.0
HKD2_k127_7877317_3 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 353.0
HKD2_k127_7877317_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 333.0
HKD2_k127_7877317_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001088 210.0
HKD2_k127_7877317_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000002647 151.0
HKD2_k127_7877317_7 Ferric reductase like transmembrane component - - - 0.00000000000000000000000002579 121.0
HKD2_k127_7877317_8 Serine aminopeptidase, S33 - - - 0.00000000000000000001225 104.0
HKD2_k127_7877317_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000001848 84.0
HKD2_k127_7886078_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 2.689e-220 712.0
HKD2_k127_7886078_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 495.0
HKD2_k127_7886078_10 Protein of unknown function (DUF1232) - - - 0.000009325 55.0
HKD2_k127_7886078_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 480.0
HKD2_k127_7886078_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 372.0
HKD2_k127_7886078_4 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 341.0
HKD2_k127_7886078_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001646 267.0
HKD2_k127_7886078_6 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000006624 194.0
HKD2_k127_7886078_7 Binds to the 23S rRNA K02939 - - 0.000000000000000000000001662 115.0
HKD2_k127_7886078_8 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000002162 107.0
HKD2_k127_7886078_9 Acetyltransferase (GNAT) family - - - 0.0000007275 61.0
HKD2_k127_7929681_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 8.198e-277 876.0
HKD2_k127_7929681_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 314.0
HKD2_k127_7929681_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000002499 93.0
HKD2_k127_7929681_11 nitrite reductase [NAD(P)H] activity K05710 - - 0.0000000000000000008024 93.0
HKD2_k127_7929681_12 - - - - 0.0000007489 60.0
HKD2_k127_7929681_13 Sortase family K07284 - 3.4.22.70 0.0000128 56.0
HKD2_k127_7929681_2 COGs COG3367 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 309.0
HKD2_k127_7929681_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008697 260.0
HKD2_k127_7929681_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000002683 238.0
HKD2_k127_7929681_5 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000006209 207.0
HKD2_k127_7929681_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000003176 184.0
HKD2_k127_7929681_7 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000000000000000471 146.0
HKD2_k127_7929681_8 cellulase activity - - - 0.0000000000000000000000000001463 134.0
HKD2_k127_7929681_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000001782 114.0
HKD2_k127_7977016_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 551.0
HKD2_k127_7977016_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 499.0
HKD2_k127_7977016_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 468.0
HKD2_k127_7977016_3 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000003876 236.0
HKD2_k127_7977016_4 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000001744 217.0
HKD2_k127_7977016_5 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000000004302 100.0
HKD2_k127_7977016_6 - - - - 0.0000000000002995 73.0
HKD2_k127_7990717_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 487.0
HKD2_k127_7990717_1 PFAM Prolyl oligopeptidase family K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 480.0
HKD2_k127_7990717_10 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000003251 163.0
HKD2_k127_7990717_11 BMC K04027 - - 0.0000000000000000000000000000000000001976 144.0
HKD2_k127_7990717_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000001393 141.0
HKD2_k127_7990717_13 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000002012 122.0
HKD2_k127_7990717_14 propanediol utilization protein - - - 0.00000000000000000000000005556 125.0
HKD2_k127_7990717_15 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000002637 103.0
HKD2_k127_7990717_16 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000259 92.0
HKD2_k127_7990717_17 PFAM Ethanolamine utilisation protein EutN carboxysome K04028 - - 0.0000000008738 68.0
HKD2_k127_7990717_18 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000005361 62.0
HKD2_k127_7990717_19 Hint domain - - - 0.0005035 54.0
HKD2_k127_7990717_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 415.0
HKD2_k127_7990717_20 EamA-like transporter family - - - 0.0008562 43.0
HKD2_k127_7990717_3 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 431.0
HKD2_k127_7990717_4 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 374.0
HKD2_k127_7990717_5 PFAM BMC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 288.0
HKD2_k127_7990717_6 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003923 282.0
HKD2_k127_7990717_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
HKD2_k127_7990717_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000005355 229.0
HKD2_k127_7990717_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002805 194.0
HKD2_k127_8015399_0 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 319.0
HKD2_k127_8015399_1 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000006892 241.0
HKD2_k127_8015399_2 - K07403 - - 0.0000000000000000000000000000000000000000000000000000001241 224.0
HKD2_k127_8015399_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000001704 179.0
HKD2_k127_8015399_4 Prephenate dehydrogenase K00210,K00220,K04517 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000001545 166.0
HKD2_k127_8015399_5 phosphoesterase (MutT family) - - - 0.00000000000000000000000000008094 131.0
HKD2_k127_8015399_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000003526 129.0
HKD2_k127_8037121_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 9.769e-233 728.0
HKD2_k127_8037121_1 carboxylase K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 493.0
HKD2_k127_8037121_2 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 308.0
HKD2_k127_8037121_3 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000673 233.0
HKD2_k127_8037121_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000078 244.0
HKD2_k127_8037121_5 SMART HNH nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000734 214.0
HKD2_k127_8037121_6 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000005329 176.0
HKD2_k127_8037121_7 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000002289 123.0
HKD2_k127_8037121_8 - - - - 0.000009414 53.0
HKD2_k127_8277269_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 562.0
HKD2_k127_8277269_1 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 444.0
HKD2_k127_8277269_10 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 310.0
HKD2_k127_8277269_11 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001854 252.0
HKD2_k127_8277269_12 amine dehydrogenase activity K08282,K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000001422 252.0
HKD2_k127_8277269_13 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000001515 241.0
HKD2_k127_8277269_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000003228 197.0
HKD2_k127_8277269_15 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000519 204.0
HKD2_k127_8277269_16 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000005143 181.0
HKD2_k127_8277269_17 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000003942 166.0
HKD2_k127_8277269_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000004608 170.0
HKD2_k127_8277269_19 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000006266 172.0
HKD2_k127_8277269_2 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 417.0
HKD2_k127_8277269_20 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000004583 148.0
HKD2_k127_8277269_21 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000001312 134.0
HKD2_k127_8277269_22 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000003975 139.0
HKD2_k127_8277269_23 Rhodanese domain protein K01069 - 3.1.2.6 0.0000000000000000000000005618 108.0
HKD2_k127_8277269_24 PFAM Rieske 2Fe-2S domain protein K02636 - 1.10.9.1 0.000000000000000006278 91.0
HKD2_k127_8277269_3 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 404.0
HKD2_k127_8277269_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 385.0
HKD2_k127_8277269_5 Histidine kinase-like ATPases K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 333.0
HKD2_k127_8277269_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 318.0
HKD2_k127_8277269_7 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 302.0
HKD2_k127_8277269_8 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
HKD2_k127_8277269_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
HKD2_k127_8363249_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.235e-194 635.0
HKD2_k127_8363249_1 FtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 484.0
HKD2_k127_8363249_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000002385 203.0
HKD2_k127_8363249_3 SMART helix-turn-helix domain protein - - - 0.000000000000002418 88.0
HKD2_k127_836661_0 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 289.0
HKD2_k127_836661_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000004485 278.0
HKD2_k127_836661_2 response regulator receiver K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000001014 223.0
HKD2_k127_836661_3 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000000000003833 229.0
HKD2_k127_836661_4 Histidine kinase K10681 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001539 201.0
HKD2_k127_836661_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000001067 138.0
HKD2_k127_836661_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000006018 110.0
HKD2_k127_836661_7 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000002694 78.0
HKD2_k127_836661_8 methyltransferase K00573 - 2.1.1.77 0.0000000007245 68.0
HKD2_k127_836661_9 CarboxypepD_reg-like domain K13276 - - 0.00000001472 66.0
HKD2_k127_8867902_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6e-323 1011.0
HKD2_k127_8867902_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 4.079e-198 670.0
HKD2_k127_8867902_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 542.0
HKD2_k127_8867902_3 - - - - 0.00000000000000000000000000000000000002546 149.0
HKD2_k127_8867902_4 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000002315 136.0
HKD2_k127_8867902_5 Putative stress-induced transcription regulator - - - 0.000000000000000000001023 102.0
HKD2_k127_8867902_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000003226 107.0
HKD2_k127_8867902_7 YbaK prolyl-tRNA synthetase associated K19055 - - 0.0000000000000002805 93.0
HKD2_k127_8867902_8 impB/mucB/samB family K14161 - - 0.0000000000002509 83.0
HKD2_k127_8867902_9 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000007846 57.0
HKD2_k127_8983329_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.399e-290 915.0
HKD2_k127_8983329_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.028e-267 854.0
HKD2_k127_8983329_10 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001854 263.0
HKD2_k127_8983329_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002339 264.0
HKD2_k127_8983329_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000006006 229.0
HKD2_k127_8983329_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000008068 196.0
HKD2_k127_8983329_14 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000002737 151.0
HKD2_k127_8983329_15 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000000000000000002579 149.0
HKD2_k127_8983329_16 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000000000002018 138.0
HKD2_k127_8983329_17 Acetyltransferase (GNAT) family K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.00000000000000000000000004191 115.0
HKD2_k127_8983329_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000001447 116.0
HKD2_k127_8983329_19 Thioesterase superfamily - - - 0.000000000000000000000001894 111.0
HKD2_k127_8983329_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 2.119e-264 840.0
HKD2_k127_8983329_20 Binds the 23S rRNA K02909 - - 0.000000000000000000000007612 105.0
HKD2_k127_8983329_21 Acetyltransferase (GNAT) family - - - 0.000000000000000000000228 108.0
HKD2_k127_8983329_22 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000006954 104.0
HKD2_k127_8983329_23 Dna alkylation repair - - - 0.0000003932 61.0
HKD2_k127_8983329_24 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000008485 55.0
HKD2_k127_8983329_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 473.0
HKD2_k127_8983329_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 365.0
HKD2_k127_8983329_5 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 373.0
HKD2_k127_8983329_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 364.0
HKD2_k127_8983329_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 345.0
HKD2_k127_8983329_8 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 306.0
HKD2_k127_8983329_9 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
HKD2_k127_9071409_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 7.097e-232 747.0
HKD2_k127_9071409_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.024e-204 655.0
HKD2_k127_9071409_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD2_k127_9071409_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000002905 222.0
HKD2_k127_9071409_4 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000003019 180.0
HKD2_k127_9071409_5 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000249 134.0
HKD2_k127_9071409_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000008382 128.0
HKD2_k127_9071409_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000666 99.0
HKD2_k127_9071409_8 Protein of unknown function (DUF448) K07742 - - 0.0000000000000235 85.0
HKD2_k127_9089544_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 445.0
HKD2_k127_9089544_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 456.0
HKD2_k127_9089544_10 cellulase activity - - - 0.00000000000000000000000001022 129.0
HKD2_k127_9089544_11 Glycosyltransferase group 2 family protein - - - 0.00000000000000000001656 105.0
HKD2_k127_9089544_12 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000002404 106.0
HKD2_k127_9089544_13 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000108 102.0
HKD2_k127_9089544_15 C-terminal domain of CHU protein family - - - 0.0004809 53.0
HKD2_k127_9089544_2 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 412.0
HKD2_k127_9089544_3 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 391.0
HKD2_k127_9089544_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
HKD2_k127_9089544_5 ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000000000000000000000000000001722 221.0
HKD2_k127_9089544_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000002447 177.0
HKD2_k127_9089544_7 Pfam Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000961 172.0
HKD2_k127_9089544_8 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.0000000000000000000000000000000002164 154.0
HKD2_k127_9089544_9 Transport permease protein K09688,K09690 - - 0.000000000000000000000000000000008118 143.0
HKD2_k127_9147374_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 579.0
HKD2_k127_9147374_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000001429 239.0
HKD2_k127_9147374_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000002402 236.0
HKD2_k127_9147374_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000006608 228.0
HKD2_k127_9147374_4 Response regulator receiver K07667 - - 0.00000000000000000000000000000000000000000000000000000000643 213.0
HKD2_k127_9147374_5 DNA binding domain - - - 0.00000000000000000008215 92.0
HKD2_k127_9170737_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.269e-266 837.0
HKD2_k127_9170737_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 349.0
HKD2_k127_9170737_2 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008603 266.0
HKD2_k127_9170737_3 Cysteine desulfurase family protein, VC1184 subfamily - - - 0.00000000000000000000000000000000000000000000002111 175.0
HKD2_k127_9170737_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000003589 160.0
HKD2_k127_9170737_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000008978 136.0
HKD2_k127_9170737_6 Cupin domain - - - 0.0000000000000000000000000005773 120.0
HKD2_k127_9205462_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 341.0
HKD2_k127_9205462_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005168 246.0
HKD2_k127_9205462_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
HKD2_k127_9205462_3 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.000000000000000000000000000000004899 140.0
HKD2_k127_9205462_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000001083 123.0
HKD2_k127_9205462_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000005272 102.0
HKD2_k127_9205462_6 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000006648 97.0
HKD2_k127_9205462_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000007034 51.0
HKD2_k127_9236414_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 357.0
HKD2_k127_9236414_1 aminopeptidase N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001805 272.0
HKD2_k127_9236414_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000001646 196.0
HKD2_k127_9236414_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000003333 181.0
HKD2_k127_9236414_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000003024 190.0
HKD2_k127_9236414_5 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000003343 146.0
HKD2_k127_9236414_6 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000001559 142.0
HKD2_k127_9236414_7 diguanylate cyclase - - - 0.00000000000000000000000000000001684 148.0
HKD2_k127_9236414_8 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000006995 112.0
HKD2_k127_9236414_9 membrane K06194 - - 0.0004268 53.0
HKD2_k127_9240642_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1123.0
HKD2_k127_9240642_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 610.0
HKD2_k127_9240642_10 Rossmann-like domain - - - 0.000000000000000000000000000000000000003285 161.0
HKD2_k127_9240642_11 NUDIX domain - - - 0.0000000000000000000000000004008 123.0
HKD2_k127_9240642_12 Cold shock K03704 - - 0.000000004244 64.0
HKD2_k127_9240642_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 409.0
HKD2_k127_9240642_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 406.0
HKD2_k127_9240642_4 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 351.0
HKD2_k127_9240642_5 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 336.0
HKD2_k127_9240642_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002025 278.0
HKD2_k127_9240642_7 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000358 224.0
HKD2_k127_9240642_8 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000215 201.0
HKD2_k127_9240642_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000005163 170.0
HKD2_k127_9269753_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 3.023e-277 876.0
HKD2_k127_9269753_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 450.0
HKD2_k127_9269753_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 329.0
HKD2_k127_9269753_3 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001277 227.0
HKD2_k127_9269753_4 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000002045 117.0
HKD2_k127_9269753_5 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.0000000000000000000001531 111.0
HKD2_k127_9269753_6 - - - - 0.000000004647 69.0
HKD2_k127_9269753_7 RDD family - - - 0.0001766 53.0
HKD2_k127_9430698_0 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 524.0
HKD2_k127_9430698_1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003113 280.0
HKD2_k127_9430698_10 PFAM Vitamin K epoxide reductase - - - 0.00000002088 68.0
HKD2_k127_9430698_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001093 231.0
HKD2_k127_9430698_3 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000002185 166.0
HKD2_k127_9430698_4 Ferric reductase like transmembrane component K17247 - - 0.00000000000000000000000000000001565 142.0
HKD2_k127_9430698_5 Lipocalin-like domain - - - 0.00000000000000000000000000008355 119.0
HKD2_k127_9430698_6 DSBA-like thioredoxin domain - - - 0.0000000000000000000000001216 123.0
HKD2_k127_9430698_7 transcriptional regulator - - - 0.000000000000000003824 91.0
HKD2_k127_9430698_9 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000004495 85.0
HKD2_k127_9492447_0 Nucleotidyl transferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 484.0
HKD2_k127_9492447_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007334 298.0
HKD2_k127_9492447_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000001846 226.0
HKD2_k127_9492447_3 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000004525 215.0
HKD2_k127_9492447_4 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000002537 177.0
HKD2_k127_9492447_5 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000004162 176.0
HKD2_k127_9492447_6 PFAM peptidase K21471 - - 0.00000000000000000000000001101 126.0
HKD2_k127_9492447_7 aminopeptidase N - - - 0.000000000000009185 88.0
HKD2_k127_9492447_8 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.00000000007622 71.0
HKD2_k127_9492447_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000182 64.0
HKD2_k127_9613830_0 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 560.0
HKD2_k127_9613830_1 TIGRFAM phenylacetate-CoA oxygenase, PaaG subunit K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 429.0
HKD2_k127_9613830_10 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000005902 136.0
HKD2_k127_9613830_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000002417 119.0
HKD2_k127_9613830_12 phenylacetate catabolic process K02610 - - 0.0000000000000000007201 91.0
HKD2_k127_9613830_13 Belongs to the UPF0354 family - - - 0.00000000002029 73.0
HKD2_k127_9613830_14 PFAM Ethyl tert-butyl ether degradation EthD - - - 0.0000000002169 68.0
HKD2_k127_9613830_15 Diguanylate cyclase - - - 0.00003689 53.0
HKD2_k127_9613830_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0006958 50.0
HKD2_k127_9613830_2 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000441 287.0
HKD2_k127_9613830_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
HKD2_k127_9613830_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002066 260.0
HKD2_k127_9613830_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
HKD2_k127_9613830_6 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000003174 190.0
HKD2_k127_9613830_7 Iron-sulfur cluster assembly protein K02612 - - 0.00000000000000000000000000000000000000000001394 170.0
HKD2_k127_9613830_8 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000004884 153.0
HKD2_k127_9613830_9 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000005396 139.0
HKD2_k127_9694773_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000349 289.0
HKD2_k127_9694773_1 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000001575 243.0
HKD2_k127_9694773_2 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000002567 228.0
HKD2_k127_9694773_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000001649 209.0
HKD2_k127_9694773_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000379 187.0
HKD2_k127_9694773_5 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001712 176.0
HKD2_k127_9694773_6 PFAM Peptidase family M23 - - - 0.000000000000007302 86.0
HKD2_k127_9694773_7 MreB/Mbl protein - - - 0.0002952 53.0
HKD2_k127_973632_0 abc transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 303.0
HKD2_k127_973632_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000008536 204.0
HKD2_k127_973632_10 Alpha/beta hydrolase family K07020 - - 0.0000000000000000001712 99.0
HKD2_k127_973632_2 Involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000000000000000000000001633 198.0
HKD2_k127_973632_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000001565 144.0
HKD2_k127_973632_4 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000003565 136.0
HKD2_k127_973632_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000001799 118.0
HKD2_k127_973632_6 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000004412 113.0
HKD2_k127_973632_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000002886 120.0
HKD2_k127_973632_8 Protein of unknown function (DUF2089) - - - 0.00000000000000000000002397 102.0
HKD2_k127_973632_9 - - - - 0.0000000000000000000001362 112.0