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Overview

ID MAG01827
Name HKD2_bin.9
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family GWC2-71-9
Genus DASQPE01
Species
Assembly information
Completeness (%) 85.85
Contamination (%) 1.53
GC content (%) 72.0
N50 (bp) 11,936
Genome size (bp) 2,887,054

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2658

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10012235_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 524.0
HKD2_k127_10012235_1 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 448.0
HKD2_k127_10012235_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 446.0
HKD2_k127_10012235_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 438.0
HKD2_k127_10012235_4 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000002472 184.0
HKD2_k127_10103377_0 LVIVD repeat - - - 2.119e-281 893.0
HKD2_k127_10103377_1 BNR/Asp-box repeat - - - 1.453e-198 659.0
HKD2_k127_10103377_10 DinB family - - - 0.000000003976 65.0
HKD2_k127_10103377_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 355.0
HKD2_k127_10103377_3 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
HKD2_k127_10103377_4 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 243.0
HKD2_k127_10103377_5 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000003215 203.0
HKD2_k127_10103377_6 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000008918 153.0
HKD2_k127_10103377_7 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000001647 132.0
HKD2_k127_10103377_8 MOSC domain - - - 0.00000000001053 73.0
HKD2_k127_10103377_9 Protein of unknown function (DUF2892) - - - 0.000000002655 66.0
HKD2_k127_1029147_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 569.0
HKD2_k127_1029147_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000003498 153.0
HKD2_k127_1029147_2 MatE K03327 - - 0.0000000001129 65.0
HKD2_k127_1067120_0 COG0076 Glutamate decarboxylase and related PLP-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 501.0
HKD2_k127_1067120_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 291.0
HKD2_k127_1067120_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000165 229.0
HKD2_k127_1067120_3 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000000000000000000000000000000000000008189 166.0
HKD2_k127_1067120_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000003772 155.0
HKD2_k127_1067120_5 - - - - 0.0000000000000000000000000000000000002425 142.0
HKD2_k127_1067120_6 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000000000002858 131.0
HKD2_k127_1067120_7 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001944 125.0
HKD2_k127_1067120_9 - - - - 0.0000000009743 61.0
HKD2_k127_1072594_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.0 1071.0
HKD2_k127_1072594_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 515.0
HKD2_k127_1072594_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 451.0
HKD2_k127_1072594_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000004642 241.0
HKD2_k127_1072594_4 fumarate reductase) cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000000000000000000343 197.0
HKD2_k127_1072594_5 Flp Fap pilin component K02651 - - 0.000006327 51.0
HKD2_k127_1075475_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000006979 141.0
HKD2_k127_1075475_1 PFAM Methyltransferase - - - 0.00000000002549 76.0
HKD2_k127_1075475_2 - - - - 0.000000003021 68.0
HKD2_k127_1075475_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00004089 53.0
HKD2_k127_1078086_0 hmm pf02371 K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 345.0
HKD2_k127_1109239_0 Phosphoenolpyruvate carboxylase K01595 - 4.1.1.31 0.0 1115.0
HKD2_k127_1109239_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 5.787e-237 751.0
HKD2_k127_1109239_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 458.0
HKD2_k127_1109239_3 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 405.0
HKD2_k127_1109239_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 383.0
HKD2_k127_1109239_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.00000000000000000000000000000000001286 137.0
HKD2_k127_1109239_6 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.0000000000000000000000003571 111.0
HKD2_k127_110949_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 643.0
HKD2_k127_110949_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 589.0
HKD2_k127_110949_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 449.0
HKD2_k127_110949_3 PAS domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 380.0
HKD2_k127_110949_4 S4 RNA-binding domain K04762 - - 0.00000000000000000000000000000000000000004271 160.0
HKD2_k127_110949_5 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000003469 169.0
HKD2_k127_110949_6 Domain of unknown function (DUF1736) - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.0000000000000000000000000000004676 140.0
HKD2_k127_110949_7 outer membrane efflux protein K15725 - - 0.00001964 57.0
HKD2_k127_1159141_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 398.0
HKD2_k127_1159141_1 - - - - 0.000000000000000000000000009098 114.0
HKD2_k127_1193776_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 532.0
HKD2_k127_1193776_1 KR domain - - - 0.00000000000000000000000000000000000004186 145.0
HKD2_k127_1193776_2 - - - - 0.0000000000007532 80.0
HKD2_k127_1193776_3 membrane - - - 0.000003195 60.0
HKD2_k127_1262313_0 HypF finger K04656 - - 3.019e-233 735.0
HKD2_k127_1262313_1 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 561.0
HKD2_k127_1262313_2 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000001811 145.0
HKD2_k127_1262313_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000001282 110.0
HKD2_k127_1294727_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 385.0
HKD2_k127_1294727_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 370.0
HKD2_k127_1294947_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002115 272.0
HKD2_k127_1294947_1 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000002757 202.0
HKD2_k127_1294947_2 Kelch - - - 0.0000002164 56.0
HKD2_k127_1313006_0 ATP-dependent helicase K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 614.0
HKD2_k127_1313006_1 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 597.0
HKD2_k127_1313006_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 321.0
HKD2_k127_1313006_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
HKD2_k127_1313006_4 DinB family - - - 0.0000000000000000000000001209 113.0
HKD2_k127_1313006_5 (FHA) domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00000000000009069 84.0
HKD2_k127_1313006_6 Protein of unknown function (DUF2662) - - - 0.000000001301 70.0
HKD2_k127_1328056_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.262e-275 863.0
HKD2_k127_1328056_1 - - - - 0.000000000000000002543 98.0
HKD2_k127_1339642_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 577.0
HKD2_k127_1339642_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 518.0
HKD2_k127_1339642_10 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000004949 166.0
HKD2_k127_1339642_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000786 132.0
HKD2_k127_1339642_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000006411 127.0
HKD2_k127_1339642_14 Formiminotransferase-cyclodeaminase - - - 0.00000000000001041 85.0
HKD2_k127_1339642_15 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000859 74.0
HKD2_k127_1339642_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 449.0
HKD2_k127_1339642_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 409.0
HKD2_k127_1339642_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 347.0
HKD2_k127_1339642_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 332.0
HKD2_k127_1339642_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006508 263.0
HKD2_k127_1339642_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
HKD2_k127_1339642_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
HKD2_k127_1339642_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000006918 187.0
HKD2_k127_1352417_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1013.0
HKD2_k127_1352417_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 405.0
HKD2_k127_1352417_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 362.0
HKD2_k127_1352417_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 343.0
HKD2_k127_1352417_4 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000006566 112.0
HKD2_k127_1352417_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000007297 105.0
HKD2_k127_1369641_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005516 250.0
HKD2_k127_1369641_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000001627 179.0
HKD2_k127_1369641_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000004543 175.0
HKD2_k127_1387798_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 6.081e-269 858.0
HKD2_k127_1387798_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 605.0
HKD2_k127_1387798_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 493.0
HKD2_k127_1387798_3 PFAM ABC transporter related K02049,K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 499.0
HKD2_k127_1387798_4 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 471.0
HKD2_k127_1387798_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 313.0
HKD2_k127_1387798_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 297.0
HKD2_k127_1387798_7 MobA-Related Protein K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000008368 164.0
HKD2_k127_1393084_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 346.0
HKD2_k127_1393084_1 arginine K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 270.0
HKD2_k127_1393084_2 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000001103 207.0
HKD2_k127_1393084_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000001784 127.0
HKD2_k127_1405920_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 444.0
HKD2_k127_1405920_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 436.0
HKD2_k127_1405920_10 Binds the 23S rRNA K02909 - - 0.00000000000000000000007741 101.0
HKD2_k127_1405920_2 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 323.0
HKD2_k127_1405920_3 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 294.0
HKD2_k127_1405920_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000001688 256.0
HKD2_k127_1405920_5 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000002561 253.0
HKD2_k127_1405920_6 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
HKD2_k127_1405920_7 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000004862 220.0
HKD2_k127_1405920_8 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000001768 193.0
HKD2_k127_1405920_9 Methyltransferase small domain K02493 - 2.1.1.297 0.000000000000000000000000000000000000000004784 165.0
HKD2_k127_1412317_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1189.0
HKD2_k127_1412317_1 Amino acid permease - - - 1.445e-226 721.0
HKD2_k127_1412317_10 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 370.0
HKD2_k127_1412317_11 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 359.0
HKD2_k127_1412317_12 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 369.0
HKD2_k127_1412317_13 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 343.0
HKD2_k127_1412317_14 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
HKD2_k127_1412317_15 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006346 258.0
HKD2_k127_1412317_16 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003406 254.0
HKD2_k127_1412317_17 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000009527 251.0
HKD2_k127_1412317_18 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
HKD2_k127_1412317_19 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000006971 213.0
HKD2_k127_1412317_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.477e-211 676.0
HKD2_k127_1412317_20 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000009611 186.0
HKD2_k127_1412317_21 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000002092 181.0
HKD2_k127_1412317_22 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000002177 176.0
HKD2_k127_1412317_23 PTS system sorbose subfamily IIB component K19507 - - 0.00000000000000000000000000000000000000000007564 170.0
HKD2_k127_1412317_24 Cytochrome c - - - 0.000000000000000000000000000000000000000005456 171.0
HKD2_k127_1412317_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000002371 156.0
HKD2_k127_1412317_26 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000004604 143.0
HKD2_k127_1412317_27 TonB-dependent receptor - - - 0.000000000000000000000000000009988 124.0
HKD2_k127_1412317_28 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000002386 132.0
HKD2_k127_1412317_29 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000007499 106.0
HKD2_k127_1412317_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 602.0
HKD2_k127_1412317_30 - - - - 0.00000000000000000006383 105.0
HKD2_k127_1412317_31 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000001147 101.0
HKD2_k127_1412317_32 Regulatory protein, FmdB family - - - 0.0000000000000000002103 91.0
HKD2_k127_1412317_33 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000003954 95.0
HKD2_k127_1412317_34 PTS system fructose IIA component K02744 - - 0.0000000000000107 79.0
HKD2_k127_1412317_35 Protein of unknown function (DUF1289) K06938 - - 0.00000002264 59.0
HKD2_k127_1412317_36 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000009945 52.0
HKD2_k127_1412317_37 amine dehydrogenase activity - - - 0.0009913 49.0
HKD2_k127_1412317_4 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 520.0
HKD2_k127_1412317_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 494.0
HKD2_k127_1412317_6 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 495.0
HKD2_k127_1412317_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 395.0
HKD2_k127_1412317_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 400.0
HKD2_k127_1412317_9 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 397.0
HKD2_k127_1417486_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 1.469e-236 739.0
HKD2_k127_1417486_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 597.0
HKD2_k127_1417486_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 383.0
HKD2_k127_1417486_3 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 369.0
HKD2_k127_1417486_4 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 335.0
HKD2_k127_1417486_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 301.0
HKD2_k127_1417486_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003205 301.0
HKD2_k127_1417486_7 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000007559 200.0
HKD2_k127_1417486_8 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000001067 86.0
HKD2_k127_1417486_9 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00007484 49.0
HKD2_k127_1424197_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 336.0
HKD2_k127_1424197_1 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001055 275.0
HKD2_k127_1424197_2 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000000000000000000000000389 218.0
HKD2_k127_1424197_3 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000002405 183.0
HKD2_k127_1424197_4 polysaccharide export - - - 0.000000000000000000000000001554 123.0
HKD2_k127_1424197_5 metal-dependent phosphohydrolase HD region K07814 - - 0.0000000000000000000107 103.0
HKD2_k127_1424197_6 - - - - 0.00001217 55.0
HKD2_k127_1440801_0 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 439.0
HKD2_k127_1440801_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 396.0
HKD2_k127_1440801_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000003094 224.0
HKD2_k127_1440801_3 Protein of unknown function (DUF3465) - - - 0.000000000000000000000000000001104 127.0
HKD2_k127_1440801_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000004536 123.0
HKD2_k127_1440801_5 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000001998 97.0
HKD2_k127_1440801_6 BON domain - - - 0.000000000002865 70.0
HKD2_k127_1464899_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 362.0
HKD2_k127_1464899_1 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
HKD2_k127_1464899_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000006376 168.0
HKD2_k127_1464899_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000002013 98.0
HKD2_k127_149469_0 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 496.0
HKD2_k127_149469_1 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 410.0
HKD2_k127_149469_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 374.0
HKD2_k127_149469_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 326.0
HKD2_k127_149469_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 316.0
HKD2_k127_149469_5 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 333.0
HKD2_k127_149469_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000007459 198.0
HKD2_k127_149469_7 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000005398 197.0
HKD2_k127_149469_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000002834 139.0
HKD2_k127_1504159_0 choline dehydrogenase activity K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 2.977e-242 762.0
HKD2_k127_1504159_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 382.0
HKD2_k127_1504159_10 ABC1 family K03688 - - 0.000000000000000000000000003314 115.0
HKD2_k127_1504159_11 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000001426 98.0
HKD2_k127_1504159_12 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000001501 87.0
HKD2_k127_1504159_13 XdhC and CoxI family - - - 0.000000009164 60.0
HKD2_k127_1504159_14 SMART PAS domain containing protein - - - 0.0000001146 59.0
HKD2_k127_1504159_2 SMART von Willebrand factor, type A K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 308.0
HKD2_k127_1504159_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008411 248.0
HKD2_k127_1504159_4 transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002567 246.0
HKD2_k127_1504159_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000001709 211.0
HKD2_k127_1504159_6 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000002314 214.0
HKD2_k127_1504159_7 phosphonoacetaldehyde hydrolase activity K19270 - 3.1.3.23 0.0000000000000000000000000000000000000000000008631 175.0
HKD2_k127_1504159_8 'Molybdopterin - - - 0.000000000000000000000000000000000000001772 171.0
HKD2_k127_1504159_9 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000002106 146.0
HKD2_k127_1530846_0 Ammonium Transporter K03320 - - 1.817e-199 634.0
HKD2_k127_1530846_1 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 389.0
HKD2_k127_1530846_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 390.0
HKD2_k127_1530846_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000003322 189.0
HKD2_k127_1579944_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 413.0
HKD2_k127_1579944_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
HKD2_k127_1600507_0 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 574.0
HKD2_k127_1600507_1 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000000000000000000000000002727 187.0
HKD2_k127_1617835_0 permease - - - 0.00000000000000000000000000000000000000000002919 170.0
HKD2_k127_1617835_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000004675 145.0
HKD2_k127_1617835_3 Protein of unknown function (DUF2752) - - - 0.00000072 59.0
HKD2_k127_1617835_4 - - - - 0.000003821 57.0
HKD2_k127_1629684_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000003342 210.0
HKD2_k127_1629684_1 MerR HTH family regulatory protein - - - 0.000000000000000000000000000001981 134.0
HKD2_k127_1629684_2 cheY-homologous receiver domain - - - 0.000000001939 64.0
HKD2_k127_1629684_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000002742 61.0
HKD2_k127_1665796_0 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 352.0
HKD2_k127_1665796_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 331.0
HKD2_k127_1665796_10 NlpC/P60 family - - - 0.00000000000000000000000000000001336 139.0
HKD2_k127_1665796_11 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000001767 138.0
HKD2_k127_1665796_12 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000004203 144.0
HKD2_k127_1665796_13 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000005472 64.0
HKD2_k127_1665796_14 PFAM YbbR family protein - - - 0.0000004679 61.0
HKD2_k127_1665796_2 Iron Permease K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 339.0
HKD2_k127_1665796_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002893 246.0
HKD2_k127_1665796_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000006265 240.0
HKD2_k127_1665796_5 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000002343 196.0
HKD2_k127_1665796_6 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000002363 173.0
HKD2_k127_1665796_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000002129 148.0
HKD2_k127_1665796_8 CYTH domain K01768,K05873 - 4.6.1.1 0.00000000000000000000000000000000000007853 158.0
HKD2_k127_1665796_9 DinB superfamily - - - 0.0000000000000000000000000000000002966 137.0
HKD2_k127_1736043_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 457.0
HKD2_k127_1736043_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000002664 171.0
HKD2_k127_1736043_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000005066 132.0
HKD2_k127_1792940_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.65e-276 863.0
HKD2_k127_1792940_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 474.0
HKD2_k127_1792940_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000006315 226.0
HKD2_k127_1792940_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000009378 215.0
HKD2_k127_1792940_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000001569 90.0
HKD2_k127_1792940_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000004954 84.0
HKD2_k127_1792940_6 protein conserved in bacteria K09764 - - 0.00000000000006026 75.0
HKD2_k127_1792940_7 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family - - - 0.000000000009349 72.0
HKD2_k127_1840649_0 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 405.0
HKD2_k127_1840649_1 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
HKD2_k127_188638_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000002043 194.0
HKD2_k127_188638_1 Methyltransferase K00587 - 2.1.1.100 0.000000000000000000000000000000000000000000115 165.0
HKD2_k127_188638_2 Dehydrogenase K00114 - 1.1.2.8 0.00000000000000000000000000000000002421 136.0
HKD2_k127_188638_3 - - - - 0.00000000000003345 85.0
HKD2_k127_188638_4 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000004931 67.0
HKD2_k127_188638_5 - - - - 0.00001397 57.0
HKD2_k127_188638_6 - - - - 0.0005439 51.0
HKD2_k127_2027495_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 561.0
HKD2_k127_2027495_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 554.0
HKD2_k127_2027495_10 Iron-binding zinc finger CDGSH type - - - 0.000000003532 62.0
HKD2_k127_2027495_11 - - - - 0.00000003393 57.0
HKD2_k127_2027495_12 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00004399 57.0
HKD2_k127_2027495_2 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 531.0
HKD2_k127_2027495_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 395.0
HKD2_k127_2027495_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 391.0
HKD2_k127_2027495_5 Zn-dependent protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 367.0
HKD2_k127_2027495_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 364.0
HKD2_k127_2027495_7 Rhomboid family - - - 0.0000000000000000000000000000000003349 143.0
HKD2_k127_2027495_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002512 118.0
HKD2_k127_2027495_9 Ribosomal protein L34 K02914 - - 0.00000000000000002656 82.0
HKD2_k127_203091_0 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 512.0
HKD2_k127_203091_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 425.0
HKD2_k127_203091_2 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000001669 123.0
HKD2_k127_203091_3 Bacterial Ig-like domain 2 - - - 0.0000000000000000006246 102.0
HKD2_k127_2054070_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004906 283.0
HKD2_k127_2054070_1 polysaccharide biosynthetic process K19431 - - 0.000000000000000000000000000000000000000000000000000000000000000000001198 263.0
HKD2_k127_2054070_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000006956 226.0
HKD2_k127_2054070_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000003555 201.0
HKD2_k127_2054070_5 Glycosyl transferase family 21 - - - 0.0000000000000004066 89.0
HKD2_k127_2078071_0 Phenylalanine-4-hydroxylase K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 480.0
HKD2_k127_2078071_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 342.0
HKD2_k127_2078071_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004722 286.0
HKD2_k127_2078071_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000007625 152.0
HKD2_k127_2078071_4 chaperone-mediated protein folding K02660 - - 0.00000000000003012 85.0
HKD2_k127_21114_0 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 571.0
HKD2_k127_21114_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 386.0
HKD2_k127_21114_2 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000009277 199.0
HKD2_k127_2122840_0 DEAD DEAH box helicase K03724 - - 0.0 1580.0
HKD2_k127_2122840_1 56kDa selenium binding protein (SBP56) K17285 - - 6.096e-229 722.0
HKD2_k127_2122840_10 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 388.0
HKD2_k127_2122840_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002342 252.0
HKD2_k127_2122840_12 PFAM Rieske 2Fe-2S domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000009809 222.0
HKD2_k127_2122840_13 - - - - 0.000000000000000000000000000000000000000000000000000000001285 213.0
HKD2_k127_2122840_14 - - - - 0.00000000000000000000000000000000000000000000000000000001101 213.0
HKD2_k127_2122840_15 Cupin domain - - - 0.0000000000000000000000000000000000000004259 155.0
HKD2_k127_2122840_16 Cold shock K03704 - - 0.00000000000000000000000000000000007983 136.0
HKD2_k127_2122840_17 protein kinase activity K12132 - 2.7.11.1 0.000000000000000001989 85.0
HKD2_k127_2122840_18 - - - - 0.000000000001104 74.0
HKD2_k127_2122840_19 Domain of unknown function (DUF4142) K08995 - - 0.0000002482 62.0
HKD2_k127_2122840_2 radical SAM domain protein - - - 2.111e-211 670.0
HKD2_k127_2122840_20 - - - - 0.00002961 57.0
HKD2_k127_2122840_21 motor activity - - - 0.00008397 56.0
HKD2_k127_2122840_3 imidazolonepropionase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 581.0
HKD2_k127_2122840_4 Cytochrome c K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 571.0
HKD2_k127_2122840_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 593.0
HKD2_k127_2122840_6 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 499.0
HKD2_k127_2122840_7 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 505.0
HKD2_k127_2122840_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 400.0
HKD2_k127_2122840_9 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 373.0
HKD2_k127_2165118_0 AcrB/AcrD/AcrF family K07787,K15726 - - 1.675e-198 626.0
HKD2_k127_2165118_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0006987 52.0
HKD2_k127_2177534_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 5.358e-209 659.0
HKD2_k127_2177534_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000001507 222.0
HKD2_k127_2177534_2 Zincin-like metallopeptidase - - - 0.000000000000002066 85.0
HKD2_k127_2181597_0 PFAM ATP dependent DNA ligase domain protein K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 625.0
HKD2_k127_2181597_1 nucleic acid phosphodiester bond hydrolysis K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 401.0
HKD2_k127_2181597_2 Asparaginase glutaminase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 379.0
HKD2_k127_2181597_3 PFAM tRNA synthetase class II (D K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 291.0
HKD2_k127_218294_0 cellulose binding - - - 3.764e-246 788.0
HKD2_k127_218294_1 transcription factor binding K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 592.0
HKD2_k127_218294_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 407.0
HKD2_k127_218294_3 Pfam:SusD K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000001015 247.0
HKD2_k127_218294_4 CarboxypepD_reg-like domain - - - 0.00000000000000000001185 93.0
HKD2_k127_2268445_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1084.0
HKD2_k127_2268445_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.196e-275 870.0
HKD2_k127_2268445_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 421.0
HKD2_k127_2268445_11 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 385.0
HKD2_k127_2268445_12 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 410.0
HKD2_k127_2268445_13 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 379.0
HKD2_k127_2268445_14 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 349.0
HKD2_k127_2268445_15 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 341.0
HKD2_k127_2268445_16 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 333.0
HKD2_k127_2268445_17 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 300.0
HKD2_k127_2268445_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 293.0
HKD2_k127_2268445_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009614 263.0
HKD2_k127_2268445_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 5.268e-221 694.0
HKD2_k127_2268445_20 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000006389 267.0
HKD2_k127_2268445_21 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
HKD2_k127_2268445_22 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006876 255.0
HKD2_k127_2268445_23 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000003128 243.0
HKD2_k127_2268445_24 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000001148 239.0
HKD2_k127_2268445_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
HKD2_k127_2268445_26 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000003542 216.0
HKD2_k127_2268445_27 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000009177 216.0
HKD2_k127_2268445_28 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000002128 193.0
HKD2_k127_2268445_29 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000008199 187.0
HKD2_k127_2268445_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.278e-196 654.0
HKD2_k127_2268445_30 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000008942 155.0
HKD2_k127_2268445_31 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000001333 145.0
HKD2_k127_2268445_32 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.00000000000000000000000000000000001714 142.0
HKD2_k127_2268445_33 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000002045 147.0
HKD2_k127_2268445_34 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000000249 156.0
HKD2_k127_2268445_35 diguanylate cyclase - - - 0.00000000000000000000000000007774 135.0
HKD2_k127_2268445_36 chemotaxis, protein K03406 - - 0.00000000000000000000000008423 125.0
HKD2_k127_2268445_37 Belongs to the TrpC family K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000004064 102.0
HKD2_k127_2268445_38 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000007707 90.0
HKD2_k127_2268445_39 Transcription factor zinc-finger K09981 - - 0.000000000000003165 84.0
HKD2_k127_2268445_4 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 605.0
HKD2_k127_2268445_40 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000005857 75.0
HKD2_k127_2268445_41 LytR cell envelope-related transcriptional attenuator - - - 0.0000000009439 71.0
HKD2_k127_2268445_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 587.0
HKD2_k127_2268445_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 555.0
HKD2_k127_2268445_7 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 535.0
HKD2_k127_2268445_8 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 552.0
HKD2_k127_2268445_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 467.0
HKD2_k127_23169_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.097e-238 772.0
HKD2_k127_23169_1 chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 628.0
HKD2_k127_23169_10 - - - - 0.0000000006086 64.0
HKD2_k127_23169_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 492.0
HKD2_k127_23169_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 318.0
HKD2_k127_23169_4 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
HKD2_k127_23169_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000004654 200.0
HKD2_k127_23169_6 Redoxin domain protein - - - 0.000000000000000000000000000000000000000009396 162.0
HKD2_k127_23169_7 DUF218 domain - - - 0.00000000000000000000000000000000000000005306 166.0
HKD2_k127_23169_8 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000005286 134.0
HKD2_k127_23169_9 Sporulation related domain - - - 0.0000000000000000000004554 108.0
HKD2_k127_2319734_0 Belongs to the class-II DAHP synthase family K01626,K16019 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0022607,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.5.1.54 4.605e-292 899.0
HKD2_k127_2319734_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000002267 111.0
HKD2_k127_2327473_0 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 514.0
HKD2_k127_2327473_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 452.0
HKD2_k127_2327473_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 362.0
HKD2_k127_2327473_3 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 287.0
HKD2_k127_2327473_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000003532 251.0
HKD2_k127_2327473_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000003481 232.0
HKD2_k127_2327473_6 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000001533 177.0
HKD2_k127_2327473_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000008969 138.0
HKD2_k127_2327473_8 - - - - 0.0000339 55.0
HKD2_k127_234647_0 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 359.0
HKD2_k127_234647_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 347.0
HKD2_k127_234647_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000886 48.0
HKD2_k127_234647_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 333.0
HKD2_k127_234647_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 312.0
HKD2_k127_234647_4 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000006074 251.0
HKD2_k127_234647_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000521 228.0
HKD2_k127_234647_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000001947 216.0
HKD2_k127_234647_7 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000004459 186.0
HKD2_k127_234647_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000001259 194.0
HKD2_k127_234647_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001812 70.0
HKD2_k127_2347162_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 615.0
HKD2_k127_2347162_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 535.0
HKD2_k127_2347162_2 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 299.0
HKD2_k127_2347162_3 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000006258 85.0
HKD2_k127_2347162_4 Ribosomal protein S21 K02970 - - 0.000000000000641 69.0
HKD2_k127_2347162_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000001682 75.0
HKD2_k127_2347162_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.00000001867 63.0
HKD2_k127_2347162_7 Vacuolar ATP synthase subunit D K02149 - - 0.000001154 59.0
HKD2_k127_238247_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.845e-293 930.0
HKD2_k127_238247_1 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 454.0
HKD2_k127_238247_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
HKD2_k127_238247_3 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007057 268.0
HKD2_k127_238247_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007421 262.0
HKD2_k127_238247_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000002591 219.0
HKD2_k127_238247_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000003155 205.0
HKD2_k127_238247_7 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000048 143.0
HKD2_k127_2482619_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 445.0
HKD2_k127_2482619_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 418.0
HKD2_k127_2482619_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 322.0
HKD2_k127_2482619_3 ketosteroid isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 311.0
HKD2_k127_2482619_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005926 272.0
HKD2_k127_2482619_5 CYTH - - - 0.000000000000000000000000000000000000000000001493 188.0
HKD2_k127_2482619_6 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000001028 106.0
HKD2_k127_2485162_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 1.49e-212 675.0
HKD2_k127_2485162_1 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 503.0
HKD2_k127_2485162_2 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 430.0
HKD2_k127_2485162_3 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 432.0
HKD2_k127_2485162_4 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 340.0
HKD2_k127_2485162_5 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000003004 157.0
HKD2_k127_2485162_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000006204 134.0
HKD2_k127_2485162_7 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000002616 126.0
HKD2_k127_2485162_8 - - - - 0.000000000000000003689 95.0
HKD2_k127_2485162_9 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000001141 65.0
HKD2_k127_2500839_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 7.327e-210 664.0
HKD2_k127_2500839_1 von Willebrand factor (vWF) type A domain - - - 7.898e-194 618.0
HKD2_k127_2500839_10 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000108 168.0
HKD2_k127_2500839_11 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000007186 166.0
HKD2_k127_2500839_12 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000001872 123.0
HKD2_k127_2500839_13 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000000007355 123.0
HKD2_k127_2500839_14 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.000000000000000000000000000339 128.0
HKD2_k127_2500839_15 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000002803 91.0
HKD2_k127_2500839_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 580.0
HKD2_k127_2500839_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 419.0
HKD2_k127_2500839_4 4Fe-4S binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 369.0
HKD2_k127_2500839_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 312.0
HKD2_k127_2500839_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 309.0
HKD2_k127_2500839_7 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000001078 233.0
HKD2_k127_2500839_8 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000002139 241.0
HKD2_k127_2500839_9 FAD linked oxidases, C-terminal domain K11472 - - 0.0000000000000000000000000000000000000000000008171 181.0
HKD2_k127_2568850_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 404.0
HKD2_k127_2568850_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000009622 194.0
HKD2_k127_2568850_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000003884 164.0
HKD2_k127_2568850_3 Transcriptional regulatory protein, C terminal K02483,K07667 GO:0008150,GO:0040007 - 0.00000000000000002269 91.0
HKD2_k127_2597102_0 ERAP1-like C-terminal domain K01256 - 3.4.11.2 2.932e-291 919.0
HKD2_k127_2597102_1 COGs COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family) - - - 0.0000000000000000000000000000000000000000000000006398 182.0
HKD2_k127_2597102_2 Uncharacterised conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.000000009261 61.0
HKD2_k127_2597102_3 - - - - 0.0002117 51.0
HKD2_k127_2613471_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.101e-311 973.0
HKD2_k127_2613471_1 Short-chain dehydrogenase reductase Sdr K00034,K00059,K03366 - 1.1.1.100,1.1.1.304,1.1.1.47,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 359.0
HKD2_k127_2637925_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 432.0
HKD2_k127_2637925_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 447.0
HKD2_k127_2637925_2 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 435.0
HKD2_k127_2637925_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005201 291.0
HKD2_k127_2637925_4 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000008536 204.0
HKD2_k127_2637925_5 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000003891 220.0
HKD2_k127_2637925_6 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000001988 193.0
HKD2_k127_2637925_7 - - - - 0.000000000000000000000000000000000000000003002 169.0
HKD2_k127_2637925_8 Cytochrome c mono- and diheme variants - - - 0.00000000007388 73.0
HKD2_k127_2637925_9 - - - - 0.000001159 60.0
HKD2_k127_2647444_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016830,GO:0016831,GO:0022607,GO:0030585,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0051291,GO:0065003,GO:0070206,GO:0070208,GO:0071840 4.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 420.0
HKD2_k127_2647444_1 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000584 260.0
HKD2_k127_2647444_2 ketosteroid isomerase - - - 0.00000000000000000000000000000001585 138.0
HKD2_k127_2647444_3 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000000000000000000008577 100.0
HKD2_k127_2647444_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000003035 96.0
HKD2_k127_2647785_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.7e-266 832.0
HKD2_k127_2647785_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 453.0
HKD2_k127_2647785_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 379.0
HKD2_k127_2647785_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 350.0
HKD2_k127_2647785_4 - - - - 0.000000000000000000003835 102.0
HKD2_k127_2647785_5 Sulfate ABC transporter periplasmic sulfate-binding protein K00956,K02048 - 2.7.7.4 0.000000000005627 69.0
HKD2_k127_2649003_0 cellulose binding - - - 2.293e-259 836.0
HKD2_k127_2649003_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 313.0
HKD2_k127_2649003_2 Fe-S protein K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001363 277.0
HKD2_k127_2649003_3 - - - - 0.00000000000005462 73.0
HKD2_k127_2676500_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 446.0
HKD2_k127_2676500_1 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 363.0
HKD2_k127_2676500_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003356 286.0
HKD2_k127_2676500_3 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001772 273.0
HKD2_k127_2676500_4 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001942 259.0
HKD2_k127_2676500_5 - - - - 0.000000000000000000006103 104.0
HKD2_k127_2678277_0 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 488.0
HKD2_k127_2678277_1 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 369.0
HKD2_k127_2678277_10 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000003718 181.0
HKD2_k127_2678277_11 - - - - 0.00000000000000000000000001603 123.0
HKD2_k127_2678277_12 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000000000001837 104.0
HKD2_k127_2678277_13 protein conserved in bacteria K09984 - - 0.0000000000000000004721 87.0
HKD2_k127_2678277_14 Psort location CytoplasmicMembrane, score - - - 0.000000002165 68.0
HKD2_k127_2678277_15 - - - - 0.0000004386 61.0
HKD2_k127_2678277_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 381.0
HKD2_k127_2678277_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HKD2_k127_2678277_4 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
HKD2_k127_2678277_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HKD2_k127_2678277_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002032 246.0
HKD2_k127_2678277_8 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000002431 214.0
HKD2_k127_2678277_9 - - - - 0.00000000000000000000000000000000000000000000000008763 192.0
HKD2_k127_2733829_0 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 491.0
HKD2_k127_2733829_1 antibiotic catabolic process K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 436.0
HKD2_k127_2733829_10 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000006532 197.0
HKD2_k127_2733829_11 acr, cog1993 K09137 - - 0.000000000000000000000000000000000000000000004512 167.0
HKD2_k127_2733829_12 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000000000007803 184.0
HKD2_k127_2733829_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000002227 151.0
HKD2_k127_2733829_14 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000001114 124.0
HKD2_k127_2733829_15 Acetyltransferase (GNAT) family - - - 0.00000000000000000000005558 111.0
HKD2_k127_2733829_16 Rad51 - - - 0.0001534 52.0
HKD2_k127_2733829_17 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0006879 45.0
HKD2_k127_2733829_2 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 426.0
HKD2_k127_2733829_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 401.0
HKD2_k127_2733829_4 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 391.0
HKD2_k127_2733829_5 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 346.0
HKD2_k127_2733829_6 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
HKD2_k127_2733829_7 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
HKD2_k127_2733829_8 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 327.0
HKD2_k127_2733829_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000005769 250.0
HKD2_k127_2735998_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 484.0
HKD2_k127_2735998_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 472.0
HKD2_k127_2735998_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 371.0
HKD2_k127_2735998_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000002732 128.0
HKD2_k127_2735998_4 Rossmann-like domain - - - 0.000000000000000000000000003878 125.0
HKD2_k127_2735998_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000001933 98.0
HKD2_k127_2795863_0 Multicopper oxidase K22348 - 1.16.3.3 3.019e-225 715.0
HKD2_k127_2795863_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 502.0
HKD2_k127_2795863_2 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 423.0
HKD2_k127_2795863_3 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 346.0
HKD2_k127_2795863_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 319.0
HKD2_k127_2795863_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 238.0
HKD2_k127_2795863_6 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000009549 194.0
HKD2_k127_2860276_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 540.0
HKD2_k127_2860276_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 458.0
HKD2_k127_2860276_10 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000006346 219.0
HKD2_k127_2860276_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000001427 204.0
HKD2_k127_2860276_12 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000005027 222.0
HKD2_k127_2860276_13 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000000000000003264 143.0
HKD2_k127_2860276_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000003636 122.0
HKD2_k127_2860276_2 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 438.0
HKD2_k127_2860276_3 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 321.0
HKD2_k127_2860276_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 296.0
HKD2_k127_2860276_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001488 288.0
HKD2_k127_2860276_6 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000001268 255.0
HKD2_k127_2860276_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.000000000000000000000000000000000000000000000000000000000000000002547 248.0
HKD2_k127_2860276_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000009045 226.0
HKD2_k127_2860276_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000008486 231.0
HKD2_k127_2869067_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1069.0
HKD2_k127_2869067_1 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 567.0
HKD2_k127_2869067_10 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001714 246.0
HKD2_k127_2869067_11 Belongs to the metal hydrolase YfiT family - - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
HKD2_k127_2869067_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
HKD2_k127_2869067_13 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000001379 192.0
HKD2_k127_2869067_14 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000001769 191.0
HKD2_k127_2869067_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001676 143.0
HKD2_k127_2869067_16 DinB superfamily - - - 0.000000000000000000000000000003543 137.0
HKD2_k127_2869067_17 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000001077 125.0
HKD2_k127_2869067_18 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000009335 94.0
HKD2_k127_2869067_19 PDZ domain - - - 0.000000000000000001089 100.0
HKD2_k127_2869067_2 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 469.0
HKD2_k127_2869067_20 - - - - 0.0000000000001373 74.0
HKD2_k127_2869067_21 Protein of unknown function (DUF3187) - - - 0.000000000189 72.0
HKD2_k127_2869067_22 Protein kinase domain K12132 - 2.7.11.1 0.00006016 52.0
HKD2_k127_2869067_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 388.0
HKD2_k127_2869067_4 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 364.0
HKD2_k127_2869067_5 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 351.0
HKD2_k127_2869067_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 336.0
HKD2_k127_2869067_7 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 333.0
HKD2_k127_2869067_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001578 276.0
HKD2_k127_2869067_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 243.0
HKD2_k127_2883836_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000003043 217.0
HKD2_k127_2883836_1 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000002482 184.0
HKD2_k127_2883836_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000004358 72.0
HKD2_k127_2905323_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 459.0
HKD2_k127_2905323_1 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 349.0
HKD2_k127_2905323_10 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000003499 168.0
HKD2_k127_2905323_11 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000004436 149.0
HKD2_k127_2905323_12 cog cog3189 - - - 0.0000000000000000000000000000000001713 151.0
HKD2_k127_2905323_13 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000003354 137.0
HKD2_k127_2905323_14 Transglycosylase associated protein - - - 0.00000000000000000000001947 106.0
HKD2_k127_2905323_15 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000001165 86.0
HKD2_k127_2905323_16 Peptidase family M23 - - - 0.0000000004439 66.0
HKD2_k127_2905323_17 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000001881 57.0
HKD2_k127_2905323_18 Protein of unknown function (DUF3761) - - - 0.000004693 58.0
HKD2_k127_2905323_19 Protein of unknown function (DUF3761) - - - 0.000006244 57.0
HKD2_k127_2905323_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 333.0
HKD2_k127_2905323_3 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009183 284.0
HKD2_k127_2905323_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004935 279.0
HKD2_k127_2905323_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001696 251.0
HKD2_k127_2905323_6 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000002763 203.0
HKD2_k127_2905323_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000004036 185.0
HKD2_k127_2905323_8 Export-related chaperone CsaA K06878 - - 0.000000000000000000000000000000000000000000001168 181.0
HKD2_k127_2905323_9 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000158 175.0
HKD2_k127_2927095_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 499.0
HKD2_k127_2927095_1 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 419.0
HKD2_k127_2927095_2 Type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000000005585 208.0
HKD2_k127_2927095_3 Type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000003698 198.0
HKD2_k127_2927095_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000014 122.0
HKD2_k127_2927095_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000006173 115.0
HKD2_k127_2927095_6 PFAM type II secretion system protein E K02283,K03609 - - 0.00000000000000000000001106 102.0
HKD2_k127_2927095_7 - - - - 0.000001809 61.0
HKD2_k127_2994429_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 518.0
HKD2_k127_2994429_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 328.0
HKD2_k127_2994429_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004513 263.0
HKD2_k127_2994429_3 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000000000000000000000000000000000000000000000000000004163 198.0
HKD2_k127_2994429_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000006512 132.0
HKD2_k127_2994429_5 Domain of unknown function (DUF4397) - - - 0.000000004811 67.0
HKD2_k127_2994429_6 Domain of unknown function (DUF4397) - - - 0.00000006042 63.0
HKD2_k127_2994429_7 glyoxalase III activity K00799,K04750 - 2.5.1.18 0.0000004664 58.0
HKD2_k127_2994429_8 Predicted membrane protein (DUF2238) K08984 - - 0.00001053 49.0
HKD2_k127_3000420_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 565.0
HKD2_k127_3000420_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000001671 168.0
HKD2_k127_3000420_2 PFAM DinB family protein - - - 0.000000000000000000000000000000000006878 142.0
HKD2_k127_3000420_3 Appr-1'-p processing enzyme - - - 0.000000001806 60.0
HKD2_k127_3021781_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 327.0
HKD2_k127_3021781_1 - - - - 0.00000000000000000000000000000001979 133.0
HKD2_k127_3021781_2 Pfam:CPSase_L_chain - - - 0.000801 49.0
HKD2_k127_303383_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 433.0
HKD2_k127_303383_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 339.0
HKD2_k127_303383_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000004701 168.0
HKD2_k127_303383_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000001136 164.0
HKD2_k127_303383_4 DinB superfamily - - - 0.000000000000000000000001567 119.0
HKD2_k127_303383_5 Preprotein translocase subunit K03210 - - 0.0000000000001017 81.0
HKD2_k127_3042013_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00366,K00381 - 1.7.7.1,1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 581.0
HKD2_k127_3042013_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 554.0
HKD2_k127_3042013_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000561 139.0
HKD2_k127_3042013_11 - - - - 0.000000000000000000008371 100.0
HKD2_k127_3042013_12 - - - - 0.0000000000003264 80.0
HKD2_k127_3042013_13 Protein of unknown function (DUF1499) - - - 0.0000000000007176 79.0
HKD2_k127_3042013_14 - - - - 0.000001604 54.0
HKD2_k127_3042013_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 325.0
HKD2_k127_3042013_3 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 291.0
HKD2_k127_3042013_4 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005312 300.0
HKD2_k127_3042013_5 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000006163 229.0
HKD2_k127_3042013_6 Glycosyl transferase family 2 K08301 - - 0.000000000000000000000000000000000000000000000000000000000291 213.0
HKD2_k127_3042013_7 - - - - 0.00000000000000000000000000000000000000000000000000009648 202.0
HKD2_k127_3042013_8 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000002702 200.0
HKD2_k127_3042013_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000003352 144.0
HKD2_k127_3058607_0 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 483.0
HKD2_k127_3058607_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.0000000000000000000000000000000000000000000000000000000000001594 220.0
HKD2_k127_3058607_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000007354 189.0
HKD2_k127_3063423_0 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 561.0
HKD2_k127_3063423_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 496.0
HKD2_k127_3063423_10 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000163 60.0
HKD2_k127_3063423_2 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 429.0
HKD2_k127_3063423_3 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 370.0
HKD2_k127_3063423_4 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
HKD2_k127_3063423_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002724 252.0
HKD2_k127_3063423_6 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000006821 198.0
HKD2_k127_3063423_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000008926 158.0
HKD2_k127_3063423_8 - - - - 0.0000000000000463 80.0
HKD2_k127_3063423_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000006496 64.0
HKD2_k127_3078875_0 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003406 280.0
HKD2_k127_3078875_1 MFS/sugar transport protein - - - 0.000000000000000002814 85.0
HKD2_k127_3078875_2 - - - - 0.000000000000000006569 96.0
HKD2_k127_3078875_3 - - - - 0.0006003 48.0
HKD2_k127_3088527_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 4.858e-310 976.0
HKD2_k127_3088527_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 335.0
HKD2_k127_3088527_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000004308 192.0
HKD2_k127_3088527_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000002724 121.0
HKD2_k127_3088527_4 - - - - 0.000000007617 62.0
HKD2_k127_3097520_0 Involved in the tonB-independent uptake of proteins - - - 6.928e-297 949.0
HKD2_k127_3097520_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 499.0
HKD2_k127_3097520_2 Sporulation related domain - - - 0.0000000000000000000000000000004604 144.0
HKD2_k127_3097520_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000254 127.0
HKD2_k127_3097520_4 DegV family - - - 0.0000000000000008044 83.0
HKD2_k127_3100051_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 1.15e-205 655.0
HKD2_k127_3100051_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 592.0
HKD2_k127_3100051_10 Bacterial regulatory proteins, tetR family - - - 0.00000000003138 72.0
HKD2_k127_3100051_2 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 563.0
HKD2_k127_3100051_3 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 353.0
HKD2_k127_3100051_4 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
HKD2_k127_3100051_5 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
HKD2_k127_3100051_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000002564 182.0
HKD2_k127_3100051_7 SprT-like family - - - 0.000000000000000000000000000000000000000000000001691 185.0
HKD2_k127_3100051_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000142 92.0
HKD2_k127_3100051_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000001714 68.0
HKD2_k127_3136611_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.65e-242 758.0
HKD2_k127_3136611_1 TrkA-C domain K03455 - - 1.523e-206 663.0
HKD2_k127_3136611_2 pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 500.0
HKD2_k127_3136611_3 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 427.0
HKD2_k127_3136611_4 MMPL family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 305.0
HKD2_k127_3136611_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000002131 236.0
HKD2_k127_3136611_6 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000001027 154.0
HKD2_k127_3136611_7 pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.0000000000000009582 79.0
HKD2_k127_3136611_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000004609 71.0
HKD2_k127_3141283_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 410.0
HKD2_k127_3141283_1 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 345.0
HKD2_k127_3141283_10 polysaccharide deacetylase - - - 0.00000000005449 76.0
HKD2_k127_3141283_2 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 309.0
HKD2_k127_3141283_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002168 287.0
HKD2_k127_3141283_4 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000184 262.0
HKD2_k127_3141283_5 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000004656 234.0
HKD2_k127_3141283_6 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000007501 184.0
HKD2_k127_3141283_7 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000001524 171.0
HKD2_k127_3141283_8 Glycosyl Transferase - - - 0.0000000000000000000000000001751 133.0
HKD2_k127_3141283_9 asparagine synthase K01953 - 6.3.5.4 0.000000000000000003803 90.0
HKD2_k127_3144072_0 B12 binding domain K00548 - 2.1.1.13 0.0 1806.0
HKD2_k127_3144072_1 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 547.0
HKD2_k127_3144072_10 YGGT family K02221 - - 0.00000000000000000000000000000000000002337 157.0
HKD2_k127_3144072_11 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000009642 138.0
HKD2_k127_3144072_12 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000007695 121.0
HKD2_k127_3144072_13 cheY-homologous receiver domain K03413 - - 0.0000000000000000000003887 102.0
HKD2_k127_3144072_14 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000000000000001981 96.0
HKD2_k127_3144072_15 PBS lyase HEAT-like repeat - - - 0.0000000000000003323 93.0
HKD2_k127_3144072_16 DUF167 K09131 - - 0.00000000000001378 85.0
HKD2_k127_3144072_18 phosphate-selective porin O and P K07221 - - 0.0008753 49.0
HKD2_k127_3144072_2 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 519.0
HKD2_k127_3144072_3 Fatty acid desaturase K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 461.0
HKD2_k127_3144072_4 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003106 297.0
HKD2_k127_3144072_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000001647 242.0
HKD2_k127_3144072_6 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000004432 231.0
HKD2_k127_3144072_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000495 193.0
HKD2_k127_3144072_8 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000002719 159.0
HKD2_k127_3144072_9 Thioredoxin-like domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000007605 155.0
HKD2_k127_3148338_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 8.84e-320 989.0
HKD2_k127_3148338_1 protein kinase activity - - - 8.722e-205 672.0
HKD2_k127_3148338_2 TonB dependent receptor K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 401.0
HKD2_k127_3148338_3 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 325.0
HKD2_k127_3148338_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA - - - 0.0000000000000000000000000000000000000000008593 175.0
HKD2_k127_3148338_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000000000000000007002 136.0
HKD2_k127_3148338_6 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000008411 127.0
HKD2_k127_3148338_7 PFAM Rv0623 family protein transcription factor K19687 - - 0.0000000000000001653 81.0
HKD2_k127_3148338_8 Ribosomal protein S21 K02970 - - 0.00002439 47.0
HKD2_k127_3179256_0 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 506.0
HKD2_k127_3179256_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000676 134.0
HKD2_k127_3179256_2 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.00000000000000004867 83.0
HKD2_k127_3191356_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 388.0
HKD2_k127_3191356_1 pilus assembly protein PilW K02672 - - 0.0000004982 60.0
HKD2_k127_3191356_2 - K02671 - - 0.000001301 60.0
HKD2_k127_3253850_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.313e-274 851.0
HKD2_k127_3253850_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 400.0
HKD2_k127_3253850_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000572 304.0
HKD2_k127_3253850_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000005397 250.0
HKD2_k127_3253850_4 - - - - 0.0000000000000000000000000000000000000000008187 179.0
HKD2_k127_3253850_5 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000000000000125 113.0
HKD2_k127_3303304_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001005 162.0
HKD2_k127_3303304_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000001285 138.0
HKD2_k127_3320581_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.321e-243 760.0
HKD2_k127_3320581_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 499.0
HKD2_k127_3320581_2 amino acid K03294 - - 0.0000000000000000001475 90.0
HKD2_k127_3320581_3 - - - - 0.00000000000003233 84.0
HKD2_k127_3320581_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000001606 50.0
HKD2_k127_3342740_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.568e-249 790.0
HKD2_k127_3342740_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 576.0
HKD2_k127_3342740_2 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 450.0
HKD2_k127_3342740_3 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 416.0
HKD2_k127_3342740_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000005006 196.0
HKD2_k127_3342740_5 Bacterial Ig-like domain - - - 0.000000000000000000000000000000000000000001413 179.0
HKD2_k127_3374870_0 FtsX-like permease family K02004 - - 5.482e-235 761.0
HKD2_k127_3374870_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 531.0
HKD2_k127_3374870_10 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 349.0
HKD2_k127_3374870_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 338.0
HKD2_k127_3374870_12 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 320.0
HKD2_k127_3374870_13 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 319.0
HKD2_k127_3374870_14 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 313.0
HKD2_k127_3374870_15 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 297.0
HKD2_k127_3374870_16 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001792 296.0
HKD2_k127_3374870_17 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000001454 241.0
HKD2_k127_3374870_18 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000003481 239.0
HKD2_k127_3374870_19 Amine oxidase, flavin-containing - - - 0.000000000000000000000000000000000000000000000000000000000000002387 236.0
HKD2_k127_3374870_2 PFAM aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 462.0
HKD2_k127_3374870_20 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000001172 223.0
HKD2_k127_3374870_21 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000008263 186.0
HKD2_k127_3374870_22 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000001366 193.0
HKD2_k127_3374870_23 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000001513 199.0
HKD2_k127_3374870_24 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001847 190.0
HKD2_k127_3374870_25 - - - - 0.00000000000000000000000000000000000000000000001447 193.0
HKD2_k127_3374870_26 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000001253 181.0
HKD2_k127_3374870_27 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000003641 175.0
HKD2_k127_3374870_28 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000002907 167.0
HKD2_k127_3374870_29 - - - - 0.00000000000000000000000000000000000009012 160.0
HKD2_k127_3374870_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 449.0
HKD2_k127_3374870_30 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000003898 159.0
HKD2_k127_3374870_31 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000001437 145.0
HKD2_k127_3374870_32 - - - - 0.00000000000000000000000000000000002804 152.0
HKD2_k127_3374870_33 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000002871 95.0
HKD2_k127_3374870_34 - - - - 0.0000000000000000007201 91.0
HKD2_k127_3374870_35 - - - - 0.00000000000000004068 96.0
HKD2_k127_3374870_36 Bacterial membrane protein YfhO - - - 0.0000000000002213 73.0
HKD2_k127_3374870_37 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000001798 76.0
HKD2_k127_3374870_4 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 445.0
HKD2_k127_3374870_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008879,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0046872,GO:0071704,GO:1901576 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 414.0
HKD2_k127_3374870_6 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 387.0
HKD2_k127_3374870_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
HKD2_k127_3374870_8 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 355.0
HKD2_k127_3374870_9 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 351.0
HKD2_k127_3380053_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000002502 241.0
HKD2_k127_3380053_1 Zinc-binding dehydrogenase - - - 0.00000000008601 71.0
HKD2_k127_3404965_1 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000255 122.0
HKD2_k127_3453065_0 response regulator K02481,K07713 - - 5.621e-264 839.0
HKD2_k127_3453065_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 524.0
HKD2_k127_3453065_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 334.0
HKD2_k127_3453065_3 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
HKD2_k127_3453065_4 Protoglobin - - - 0.0000000000000000000000000000000002115 134.0
HKD2_k127_3453065_5 zinc ion binding K06204 - - 0.000000000000000000000000000000001625 131.0
HKD2_k127_3486901_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 326.0
HKD2_k127_3486901_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003922 288.0
HKD2_k127_3486901_2 - - - - 0.000000000000000000000000000000000000000000002865 176.0
HKD2_k127_3487082_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1029.0
HKD2_k127_3487082_1 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 563.0
HKD2_k127_3487082_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000002944 154.0
HKD2_k127_3487082_11 Outer membrane lipoprotein K05807 - - 0.00000000000000000000000000000000000009022 154.0
HKD2_k127_3487082_12 TPR repeat - - - 0.000000000000000000000000000005981 128.0
HKD2_k127_3487082_2 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 562.0
HKD2_k127_3487082_3 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 503.0
HKD2_k127_3487082_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 511.0
HKD2_k127_3487082_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 439.0
HKD2_k127_3487082_6 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 320.0
HKD2_k127_3487082_7 RmlD substrate binding domain K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001134 302.0
HKD2_k127_3487082_8 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004412 271.0
HKD2_k127_3487082_9 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000009272 222.0
HKD2_k127_3491252_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 599.0
HKD2_k127_3491252_1 Multicopper oxidase K00368,K22348 - 1.16.3.3,1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 381.0
HKD2_k127_3491252_10 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000109 79.0
HKD2_k127_3491252_11 repeat protein - - - 0.0000001081 59.0
HKD2_k127_3491252_2 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 323.0
HKD2_k127_3491252_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000327 245.0
HKD2_k127_3491252_4 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000003449 183.0
HKD2_k127_3491252_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000002266 131.0
HKD2_k127_3491252_6 - - - - 0.0000000000000000000000000001187 126.0
HKD2_k127_3491252_8 Iron-sulfur cluster assembly protein - - - 0.0000000000000000006216 101.0
HKD2_k127_3491252_9 Transcriptional regulator - - - 0.0000000000000001364 88.0
HKD2_k127_355414_0 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 422.0
HKD2_k127_355414_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 371.0
HKD2_k127_355414_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000009314 111.0
HKD2_k127_3576513_0 tRNA synthetases class I (E and Q), catalytic domain K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 301.0
HKD2_k127_3576513_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002096 305.0
HKD2_k127_3576513_2 Cupin domain - - - 0.00000000000000000000000000000000000000000001849 175.0
HKD2_k127_3584480_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
HKD2_k127_3584480_1 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000000000000000000000000001582 162.0
HKD2_k127_3675994_0 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 469.0
HKD2_k127_3675994_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 455.0
HKD2_k127_3675994_10 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000001414 187.0
HKD2_k127_3675994_11 - - - - 0.00000000000000000000000000001738 132.0
HKD2_k127_3675994_12 Membrane - - - 0.0000000000000000000000000009059 130.0
HKD2_k127_3675994_13 - - - - 0.000000000000000000000000396 117.0
HKD2_k127_3675994_15 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000003774 93.0
HKD2_k127_3675994_16 PFAM Flp Fap pilin component K02651 - - 0.000005984 53.0
HKD2_k127_3675994_17 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0001541 55.0
HKD2_k127_3675994_2 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 318.0
HKD2_k127_3675994_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 296.0
HKD2_k127_3675994_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007577 248.0
HKD2_k127_3675994_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001828 230.0
HKD2_k127_3675994_6 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000005349 214.0
HKD2_k127_3675994_7 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000001767 201.0
HKD2_k127_3675994_8 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000005023 209.0
HKD2_k127_3675994_9 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000007874 211.0
HKD2_k127_3824014_0 4-hydroxyphenylacetate 3-monooxygenase oxygenase component K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 428.0
HKD2_k127_3824014_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000001255 141.0
HKD2_k127_3824014_2 - - - - 0.000000001919 63.0
HKD2_k127_3824014_3 PFAM Transposase, IS4-like - - - 0.00000004457 66.0
HKD2_k127_3824014_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0003029 50.0
HKD2_k127_384686_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 1.904e-270 847.0
HKD2_k127_384686_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 603.0
HKD2_k127_384686_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000003745 161.0
HKD2_k127_384686_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000004545 166.0
HKD2_k127_384686_4 subunit of a heme lyase K02200 - - 0.0000000000000000000000002838 120.0
HKD2_k127_3850001_0 inositol 2-dehydrogenase activity - - - 5.81e-252 798.0
HKD2_k127_3850001_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000002615 151.0
HKD2_k127_3850001_2 O-Antigen ligase - - - 0.0000000000000000000000000006407 130.0
HKD2_k127_3850001_3 deacetylase - - - 0.00000000000000000000000002117 117.0
HKD2_k127_3850001_4 anaphase-promoting complex binding K20276 - - 0.0000000009233 71.0
HKD2_k127_3850001_5 N-terminal glycosyl-hydrolase-114-associated domain - - - 0.0001034 53.0
HKD2_k127_3872024_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 530.0
HKD2_k127_3872024_1 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 500.0
HKD2_k127_3872024_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000003814 168.0
HKD2_k127_3872024_11 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000000000004729 156.0
HKD2_k127_3872024_12 Amidohydrolase family - - - 0.0000000000000000000000000000000000004659 161.0
HKD2_k127_3872024_13 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000002581 117.0
HKD2_k127_3872024_14 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000001593 106.0
HKD2_k127_3872024_15 PAP2 superfamily - - - 0.0000000000000000597 94.0
HKD2_k127_3872024_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 415.0
HKD2_k127_3872024_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
HKD2_k127_3872024_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 367.0
HKD2_k127_3872024_5 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 354.0
HKD2_k127_3872024_6 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000006771 220.0
HKD2_k127_3872024_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001438 197.0
HKD2_k127_3872024_8 PFAM Rhodanese domain protein K01011 GO:0005575,GO:0005623,GO:0042597,GO:0044464 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000002771 192.0
HKD2_k127_3872024_9 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000000001991 161.0
HKD2_k127_3893137_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 555.0
HKD2_k127_3893137_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 388.0
HKD2_k127_3893137_10 Trm112p-like protein K09791 - - 0.00000000000000001246 89.0
HKD2_k127_3893137_2 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 361.0
HKD2_k127_3893137_3 PFAM Sodium calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 324.0
HKD2_k127_3893137_4 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 322.0
HKD2_k127_3893137_5 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009379 284.0
HKD2_k127_3893137_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
HKD2_k127_3893137_7 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000004426 209.0
HKD2_k127_3893137_8 - - - - 0.00000000000000000000000000000000000000000114 168.0
HKD2_k127_3893137_9 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000006776 154.0
HKD2_k127_3908420_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.371e-219 697.0
HKD2_k127_3908420_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 1.461e-203 644.0
HKD2_k127_3908420_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000003905 81.0
HKD2_k127_3908420_2 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 572.0
HKD2_k127_3908420_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 446.0
HKD2_k127_3908420_4 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000003729 239.0
HKD2_k127_3908420_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000518 216.0
HKD2_k127_3908420_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000001477 176.0
HKD2_k127_3908420_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000008079 167.0
HKD2_k127_3908420_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000003875 126.0
HKD2_k127_3908420_9 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000005622 101.0
HKD2_k127_3940047_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.633e-233 751.0
HKD2_k127_3940047_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 582.0
HKD2_k127_3940047_10 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002488 301.0
HKD2_k127_3940047_11 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000013 274.0
HKD2_k127_3940047_12 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003265 265.0
HKD2_k127_3940047_13 asparaginase activity K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000004816 250.0
HKD2_k127_3940047_14 Nucleotidyl transferase K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000003006 208.0
HKD2_k127_3940047_15 transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000002001 196.0
HKD2_k127_3940047_16 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000004497 200.0
HKD2_k127_3940047_17 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000002449 192.0
HKD2_k127_3940047_18 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000003823 188.0
HKD2_k127_3940047_19 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000009735 179.0
HKD2_k127_3940047_2 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 589.0
HKD2_k127_3940047_20 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.00000000000000000000000000000000000005219 159.0
HKD2_k127_3940047_21 Belongs to the phosphoglycerate mutase family K02226,K22306 - 3.1.3.73,3.1.3.85 0.0000000000000000000000000626 116.0
HKD2_k127_3940047_22 PFAM Methyltransferase type 11 - - - 0.000000000000000000002029 106.0
HKD2_k127_3940047_23 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000002384 93.0
HKD2_k127_3940047_24 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000814 75.0
HKD2_k127_3940047_25 SIS domain K03271,K15669 - 2.7.7.71,5.3.1.28 0.0000000001144 71.0
HKD2_k127_3940047_26 G-rich domain on putative tyrosine kinase - - - 0.0000000002837 72.0
HKD2_k127_3940047_27 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000003246 62.0
HKD2_k127_3940047_28 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000004458 65.0
HKD2_k127_3940047_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 549.0
HKD2_k127_3940047_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 506.0
HKD2_k127_3940047_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 448.0
HKD2_k127_3940047_6 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 438.0
HKD2_k127_3940047_7 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 316.0
HKD2_k127_3940047_8 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 295.0
HKD2_k127_3940047_9 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002371 292.0
HKD2_k127_3964964_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 471.0
HKD2_k127_3964964_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 392.0
HKD2_k127_3964964_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 389.0
HKD2_k127_3964964_3 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 311.0
HKD2_k127_3964964_4 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000001175 179.0
HKD2_k127_3964964_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000006346 137.0
HKD2_k127_4001365_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1239.0
HKD2_k127_4001365_1 General secretory system II protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 612.0
HKD2_k127_4001365_10 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000303 251.0
HKD2_k127_4001365_11 Ferric uptake regulator family K22297 - - 0.00000000000000000000000000000000000000000000000000000000000001546 218.0
HKD2_k127_4001365_12 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000005013 221.0
HKD2_k127_4001365_13 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000004757 212.0
HKD2_k127_4001365_14 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000001799 199.0
HKD2_k127_4001365_15 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000001647 191.0
HKD2_k127_4001365_16 Uncharacterized conserved protein (DUF2267) - - - 0.00000000000000000000000000000000007608 138.0
HKD2_k127_4001365_17 Helix-hairpin-helix motif K02237 - - 0.00000000000000006412 89.0
HKD2_k127_4001365_18 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000002045 67.0
HKD2_k127_4001365_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 590.0
HKD2_k127_4001365_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 533.0
HKD2_k127_4001365_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 461.0
HKD2_k127_4001365_5 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 402.0
HKD2_k127_4001365_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 379.0
HKD2_k127_4001365_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 346.0
HKD2_k127_4001365_8 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 307.0
HKD2_k127_4001365_9 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007017 287.0
HKD2_k127_4014937_0 Domain of unknown function (DUF1611_C) P-loop domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 312.0
HKD2_k127_4014937_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000003522 235.0
HKD2_k127_4014937_2 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000001261 82.0
HKD2_k127_4026890_0 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
HKD2_k127_4026890_1 C4-dicarboxylate anaerobic carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
HKD2_k127_4026890_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000471 172.0
HKD2_k127_4026890_3 Putative prokaryotic signal transducing protein - - - 0.000000000286 63.0
HKD2_k127_4026890_4 Putative zincin peptidase - - - 0.000007789 49.0
HKD2_k127_4026890_5 Oligoendopeptidase f - - - 0.00001637 58.0
HKD2_k127_4028285_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 537.0
HKD2_k127_4028285_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 334.0
HKD2_k127_4028285_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000002459 255.0
HKD2_k127_4028285_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000002833 201.0
HKD2_k127_4028285_4 - - - - 0.000000000000000000000000000000000000000007585 158.0
HKD2_k127_4028285_5 - - - - 0.00000000000000000000000003145 113.0
HKD2_k127_4028285_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000008242 111.0
HKD2_k127_4046480_0 choline dehydrogenase activity - - - 8.448e-239 750.0
HKD2_k127_4046480_1 choline dehydrogenase activity - - - 8.897e-238 757.0
HKD2_k127_4046480_2 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 458.0
HKD2_k127_4046480_3 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000002863 274.0
HKD2_k127_4046480_4 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000002048 238.0
HKD2_k127_4046480_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000001615 160.0
HKD2_k127_4047809_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 595.0
HKD2_k127_4047809_1 E1-E2 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 573.0
HKD2_k127_4047809_2 response regulator K02483 - - 0.0000000000000000000000000000000000000000000000004615 180.0
HKD2_k127_4047809_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000005948 93.0
HKD2_k127_4048302_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 263.0
HKD2_k127_4048302_1 Hsp70 protein K03569 - - 0.000000000000000000000000000000002331 130.0
HKD2_k127_4072616_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.345e-305 950.0
HKD2_k127_4072616_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 512.0
HKD2_k127_4072616_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 366.0
HKD2_k127_4072616_3 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000001089 243.0
HKD2_k127_4072616_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000003322 184.0
HKD2_k127_4072616_5 Putative adhesin - - - 0.00000000000000000000000005236 125.0
HKD2_k127_4072616_7 - - - - 0.0000000000004774 78.0
HKD2_k127_4094920_0 Formate dehydrogenase alpha subunit K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 591.0
HKD2_k127_4094920_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 360.0
HKD2_k127_4094920_2 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000004867 116.0
HKD2_k127_4096705_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 585.0
HKD2_k127_4096705_1 PFAM Cation H exchanger K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 544.0
HKD2_k127_4096705_10 Anti-sigma-K factor rskA - - - 0.00000004575 65.0
HKD2_k127_4096705_11 M42 glutamyl aminopeptidase - - - 0.00000006457 64.0
HKD2_k127_4096705_12 PFAM Electron transfer DM13 - - - 0.000001621 58.0
HKD2_k127_4096705_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 523.0
HKD2_k127_4096705_3 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 349.0
HKD2_k127_4096705_4 Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006206 301.0
HKD2_k127_4096705_6 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000001243 138.0
HKD2_k127_4096705_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000002024 116.0
HKD2_k127_4096705_8 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000009992 116.0
HKD2_k127_4096705_9 - - - - 0.00000000003479 70.0
HKD2_k127_4118444_0 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 1.389e-286 895.0
HKD2_k127_4118444_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 5.812e-236 733.0
HKD2_k127_4118444_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 578.0
HKD2_k127_4118444_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000005061 148.0
HKD2_k127_4118444_4 von Willebrand factor type A domain K07114 - - 0.0000003915 55.0
HKD2_k127_4136189_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 619.0
HKD2_k127_4136189_1 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 488.0
HKD2_k127_4136189_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 462.0
HKD2_k127_4136189_3 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000009467 224.0
HKD2_k127_4136189_4 OmpA family - - - 0.0000000000000000000000000000000000002984 162.0
HKD2_k127_4136189_5 cell septum assembly K02487,K06596,K08372 - - 0.00000000000000000001579 95.0
HKD2_k127_4136189_6 Protein of unknown function (DUF2905) - - - 0.000000000000009713 76.0
HKD2_k127_4136189_7 PFAM blue (type 1) copper domain protein - - - 0.0000007937 54.0
HKD2_k127_4136189_8 YceI-like domain - - - 0.000002112 60.0
HKD2_k127_4136189_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000003269 57.0
HKD2_k127_4156289_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 343.0
HKD2_k127_4156289_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000008288 218.0
HKD2_k127_4156289_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000008984 166.0
HKD2_k127_4156289_3 Helix-turn-helix domain - - - 0.000001253 59.0
HKD2_k127_4169433_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 407.0
HKD2_k127_4169433_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 408.0
HKD2_k127_4169433_2 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 315.0
HKD2_k127_4169433_3 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000002385 231.0
HKD2_k127_4169433_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000205 194.0
HKD2_k127_4169433_5 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000001378 117.0
HKD2_k127_4177926_0 Elongation factor G C-terminus K06207 - - 8.538e-204 642.0
HKD2_k127_4177926_1 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000001128 154.0
HKD2_k127_4177926_3 cAMP biosynthetic process - - - 0.00007093 47.0
HKD2_k127_4185796_0 Bacterial regulatory protein, Fis family - - - 4.514e-215 680.0
HKD2_k127_4185796_1 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 499.0
HKD2_k127_4185796_2 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 404.0
HKD2_k127_4185796_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004366 252.0
HKD2_k127_4185796_4 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000287 177.0
HKD2_k127_4203617_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 362.0
HKD2_k127_4203617_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002515 250.0
HKD2_k127_4203617_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000005941 205.0
HKD2_k127_4203617_3 virulence factor Mce family protein K02067 - - 0.0000000000000001332 91.0
HKD2_k127_4211431_0 Malate synthase K01638 - 2.3.3.9 3.588e-276 863.0
HKD2_k127_4211431_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 330.0
HKD2_k127_4211431_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 326.0
HKD2_k127_4219649_0 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 486.0
HKD2_k127_4219649_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000009859 275.0
HKD2_k127_4219649_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000003317 230.0
HKD2_k127_4219649_3 Mazg nucleotide pyrophosphohydrolase K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000005699 181.0
HKD2_k127_4219649_4 - - - - 0.00000000008223 66.0
HKD2_k127_4219649_5 - - - - 0.0001734 48.0
HKD2_k127_4225513_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 641.0
HKD2_k127_4225513_1 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 575.0
HKD2_k127_4225513_10 siderophore receptor K02014 - - 0.000000003203 65.0
HKD2_k127_4225513_2 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 422.0
HKD2_k127_4225513_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 396.0
HKD2_k127_4225513_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 382.0
HKD2_k127_4225513_5 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000416 297.0
HKD2_k127_4225513_6 - - - - 0.0000000000000000000000000000000000000000000000000000000004151 217.0
HKD2_k127_4225513_7 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000002709 210.0
HKD2_k127_4225513_8 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000009492 154.0
HKD2_k127_4225513_9 OsmC-like protein K04063 - - 0.00000000000000000000000000000000001394 143.0
HKD2_k127_4229129_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.698e-285 882.0
HKD2_k127_4229129_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 503.0
HKD2_k127_4229129_10 Roadblock/LC7 domain K07131 - - 0.0004528 48.0
HKD2_k127_4229129_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 452.0
HKD2_k127_4229129_3 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 321.0
HKD2_k127_4229129_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006804 287.0
HKD2_k127_4229129_5 Sugar nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000016 241.0
HKD2_k127_4229129_6 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000004992 184.0
HKD2_k127_4229129_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000005805 122.0
HKD2_k127_4229129_8 - - - - 0.000000000000003999 82.0
HKD2_k127_4229129_9 PFAM blue (type 1) copper domain protein - - - 0.00003974 55.0
HKD2_k127_4309353_0 Peptidase family M3 K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 514.0
HKD2_k127_4309353_1 nucleotide catabolic process K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 448.0
HKD2_k127_4309353_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HKD2_k127_4309353_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001008 287.0
HKD2_k127_4309353_4 diguanylate cyclase - - - 0.000000000000000000000000000000000001883 154.0
HKD2_k127_4309353_5 Cold shock protein domain K03704 - - 0.000000000000000000000000000001331 125.0
HKD2_k127_4309353_6 HD domain - - - 0.00000000000000000000000000003433 124.0
HKD2_k127_4309353_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000005006 105.0
HKD2_k127_4309353_8 Putative stress-induced transcription regulator - - - 0.0000000000008773 77.0
HKD2_k127_4316105_0 WD40-like Beta Propeller Repeat - - - 1.087e-231 763.0
HKD2_k127_4316105_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 493.0
HKD2_k127_4316105_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 458.0
HKD2_k127_4316105_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
HKD2_k127_4316105_4 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000002062 252.0
HKD2_k127_4316105_5 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000479 203.0
HKD2_k127_4316105_6 CBS domain K07182 - - 0.0000000000000008993 81.0
HKD2_k127_4517485_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 377.0
HKD2_k127_4517485_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002111 258.0
HKD2_k127_4517485_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
HKD2_k127_4529837_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 519.0
HKD2_k127_4529837_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 477.0
HKD2_k127_4529837_10 Tetratricopeptide repeat - - - 0.000000004099 70.0
HKD2_k127_4529837_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 347.0
HKD2_k127_4529837_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 350.0
HKD2_k127_4529837_4 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 300.0
HKD2_k127_4529837_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000504 242.0
HKD2_k127_4529837_6 Dehydroquinase class II K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000006734 160.0
HKD2_k127_4529837_7 Domain of unknown function (DUF4321) - - - 0.000000000000000001066 101.0
HKD2_k127_4529837_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001774 77.0
HKD2_k127_4529837_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.000000000005734 71.0
HKD2_k127_4564020_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 448.0
HKD2_k127_4564020_1 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001781 289.0
HKD2_k127_4564020_2 PFAM M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000001256 126.0
HKD2_k127_4564020_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.000000000000002667 82.0
HKD2_k127_4647939_0 Aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 563.0
HKD2_k127_4647939_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
HKD2_k127_4647939_2 Protein of unknown function (DUF1097) - - - 0.0000000000000000000000000000000000000002043 161.0
HKD2_k127_4647939_3 Peptidase family M20/M25/M40 - - - 0.0000000000004551 72.0
HKD2_k127_4669940_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000001699 226.0
HKD2_k127_4669940_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000001591 219.0
HKD2_k127_4669940_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000001041 171.0
HKD2_k127_4693140_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 516.0
HKD2_k127_4693140_1 biosynthesis protein E K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 421.0
HKD2_k127_4693140_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 400.0
HKD2_k127_4693140_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000004849 193.0
HKD2_k127_4693140_4 Daunorubicin resistance abc transporter atpase subunit K01990 - - 0.000000000000000000000000000000000000000000000005745 194.0
HKD2_k127_4693140_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000002506 163.0
HKD2_k127_4693140_6 Coenzyme PQQ synthesis protein D (PqqD) K06138 - - 0.000000000001018 71.0
HKD2_k127_4754253_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 491.0
HKD2_k127_4754253_1 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 396.0
HKD2_k127_4754253_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001594 277.0
HKD2_k127_4754253_3 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004016 270.0
HKD2_k127_4754253_4 beta-lactamase - - - 0.000000000000000000000000000000000000000000000001217 189.0
HKD2_k127_4754253_5 30S ribosomal protein Thx K19033 - - 0.0002045 45.0
HKD2_k127_4879226_0 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 509.0
HKD2_k127_4879226_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 489.0
HKD2_k127_4879226_10 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000171 147.0
HKD2_k127_4879226_11 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000008191 147.0
HKD2_k127_4879226_12 Histidine triad domain protein K02503 - - 0.00000000000000000000000000000001423 131.0
HKD2_k127_4879226_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000004476 116.0
HKD2_k127_4879226_14 Ribosomal protein S21 K02970 - - 0.00000000000000000000000949 102.0
HKD2_k127_4879226_15 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000002141 103.0
HKD2_k127_4879226_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 445.0
HKD2_k127_4879226_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 416.0
HKD2_k127_4879226_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 386.0
HKD2_k127_4879226_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001674 300.0
HKD2_k127_4879226_6 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000005299 218.0
HKD2_k127_4879226_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000001277 201.0
HKD2_k127_4879226_8 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000006487 187.0
HKD2_k127_4879226_9 Met-10+ like-protein K02687 - - 0.0000000000000000000000000000000000000000002131 169.0
HKD2_k127_4879970_0 DNA recombination K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
HKD2_k127_4879970_1 RES domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002174 235.0
HKD2_k127_4879970_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000008626 176.0
HKD2_k127_4879970_3 - - - - 0.000000000000000000001587 96.0
HKD2_k127_4879970_4 - - - - 0.0000000000000000001007 98.0
HKD2_k127_4879970_5 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000531 85.0
HKD2_k127_4879970_6 - - - - 0.00000000000008405 79.0
HKD2_k127_4924261_0 Heat shock 70 kDa protein K04043 - - 1.19e-321 996.0
HKD2_k127_4924261_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 548.0
HKD2_k127_4924261_10 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
HKD2_k127_4924261_11 HAMP domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 337.0
HKD2_k127_4924261_12 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 306.0
HKD2_k127_4924261_13 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008034 278.0
HKD2_k127_4924261_14 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000008464 257.0
HKD2_k127_4924261_15 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000002646 235.0
HKD2_k127_4924261_16 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000002327 176.0
HKD2_k127_4924261_17 - - - - 0.0000000000000000000000002158 119.0
HKD2_k127_4924261_18 DNA-binding transcription factor activity K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000001551 65.0
HKD2_k127_4924261_2 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 405.0
HKD2_k127_4924261_3 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 417.0
HKD2_k127_4924261_4 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 406.0
HKD2_k127_4924261_5 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 369.0
HKD2_k127_4924261_6 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 371.0
HKD2_k127_4924261_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 340.0
HKD2_k127_4924261_8 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 325.0
HKD2_k127_4924261_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 321.0
HKD2_k127_4933854_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 444.0
HKD2_k127_4933854_1 oxidoreductase K00010 - 1.1.1.18,1.1.1.369 0.000000000000000005593 88.0
HKD2_k127_5017911_0 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 364.0
HKD2_k127_5017911_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 307.0
HKD2_k127_5017911_10 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000001406 157.0
HKD2_k127_5017911_11 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000000000004589 139.0
HKD2_k127_5017911_12 methylamine metabolic process K15977 - - 0.00000000000000000000000000000000001153 141.0
HKD2_k127_5017911_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000003046 131.0
HKD2_k127_5017911_14 - - - - 0.000000000000000000000000001457 123.0
HKD2_k127_5017911_15 membrane - - - 0.000000000000000000002584 105.0
HKD2_k127_5017911_17 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000001569 97.0
HKD2_k127_5017911_18 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000006381 86.0
HKD2_k127_5017911_19 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000001269 84.0
HKD2_k127_5017911_2 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 318.0
HKD2_k127_5017911_20 - - - - 0.000001948 58.0
HKD2_k127_5017911_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
HKD2_k127_5017911_4 COG2513 PEP phosphonomutase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005194 272.0
HKD2_k127_5017911_5 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002016 262.0
HKD2_k127_5017911_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001356 230.0
HKD2_k127_5017911_7 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000001365 190.0
HKD2_k127_5017911_8 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000521 170.0
HKD2_k127_5017911_9 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000007964 153.0
HKD2_k127_5018903_0 serine protease K07403 - - 0.0000000000000000000000000000000000002733 149.0
HKD2_k127_5018903_1 - - - - 0.00000000000006061 82.0
HKD2_k127_5029108_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.122e-218 691.0
HKD2_k127_5029108_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 373.0
HKD2_k127_5029108_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000001073 130.0
HKD2_k127_5029108_11 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000004086 118.0
HKD2_k127_5029108_12 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000004795 116.0
HKD2_k127_5029108_13 Thioesterase-like superfamily K07107 - - 0.00000000000000000000001279 114.0
HKD2_k127_5029108_14 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000001294 91.0
HKD2_k127_5029108_15 - - - - 0.000000006416 65.0
HKD2_k127_5029108_16 - - - - 0.000000007194 65.0
HKD2_k127_5029108_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 376.0
HKD2_k127_5029108_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 324.0
HKD2_k127_5029108_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 293.0
HKD2_k127_5029108_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 286.0
HKD2_k127_5029108_6 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000001696 220.0
HKD2_k127_5029108_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000133 174.0
HKD2_k127_5029108_8 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000002539 160.0
HKD2_k127_5029108_9 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000005274 150.0
HKD2_k127_510378_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 499.0
HKD2_k127_510378_1 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 336.0
HKD2_k127_510378_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001321 276.0
HKD2_k127_510378_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000001565 82.0
HKD2_k127_510378_4 Limonene-1,2-epoxide hydrolase catalytic domain K06893 - - 0.00001715 57.0
HKD2_k127_5124801_0 MMPL family K03296 - - 1.702e-302 970.0
HKD2_k127_5124801_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 424.0
HKD2_k127_5124801_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001024 297.0
HKD2_k127_5124801_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001844 269.0
HKD2_k127_5124801_4 regulation of RNA biosynthetic process - - - 0.00000000003182 70.0
HKD2_k127_5125974_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 320.0
HKD2_k127_5125974_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 276.0
HKD2_k127_5128218_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 323.0
HKD2_k127_5128218_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001493 265.0
HKD2_k127_5128218_2 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000007882 216.0
HKD2_k127_5143642_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.939e-286 897.0
HKD2_k127_5143642_1 Hsp70 protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 592.0
HKD2_k127_5143642_10 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000003542 184.0
HKD2_k127_5143642_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000002816 111.0
HKD2_k127_5143642_12 rod shape-determining protein MreD K03571 - - 0.00000000000000000000699 108.0
HKD2_k127_5143642_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 554.0
HKD2_k127_5143642_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 551.0
HKD2_k127_5143642_4 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 451.0
HKD2_k127_5143642_5 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 448.0
HKD2_k127_5143642_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 374.0
HKD2_k127_5143642_7 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 305.0
HKD2_k127_5143642_8 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 308.0
HKD2_k127_5143642_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000004746 190.0
HKD2_k127_5158043_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 448.0
HKD2_k127_5158043_1 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000002852 178.0
HKD2_k127_5158043_2 Capsule assembly protein Wzi - - - 0.0000000001128 74.0
HKD2_k127_5158043_3 DNA protecting protein DprA K04096 - - 0.00003974 51.0
HKD2_k127_5172971_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 471.0
HKD2_k127_5172971_1 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 405.0
HKD2_k127_5172971_10 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.000000000000000000000000000000000002409 148.0
HKD2_k127_5172971_11 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000000002538 148.0
HKD2_k127_5172971_12 - - - - 0.000000000000000000000000000000419 131.0
HKD2_k127_5172971_13 - - - - 0.0000000000000000000000000000388 127.0
HKD2_k127_5172971_14 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000001885 97.0
HKD2_k127_5172971_15 - - - - 0.000000000476 63.0
HKD2_k127_5172971_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 362.0
HKD2_k127_5172971_3 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 348.0
HKD2_k127_5172971_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 336.0
HKD2_k127_5172971_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HKD2_k127_5172971_6 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 303.0
HKD2_k127_5172971_7 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005463 258.0
HKD2_k127_5172971_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000001109 228.0
HKD2_k127_5172971_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000003999 205.0
HKD2_k127_5201040_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.013e-242 772.0
HKD2_k127_5201040_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 477.0
HKD2_k127_5201040_2 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 402.0
HKD2_k127_5201040_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005613 285.0
HKD2_k127_5201040_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
HKD2_k127_5201040_5 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000003554 178.0
HKD2_k127_5201040_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000001057 156.0
HKD2_k127_5201040_7 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000001411 124.0
HKD2_k127_5201040_8 - - - - 0.0000000000000000000000001272 107.0
HKD2_k127_5201040_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000174 51.0
HKD2_k127_5208835_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 432.0
HKD2_k127_5208835_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000003802 207.0
HKD2_k127_5208835_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000003821 83.0
HKD2_k127_5208835_3 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000002662 80.0
HKD2_k127_5208835_4 Domain of unknown function (DUF1732) - - - 0.0000003075 52.0
HKD2_k127_5210066_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 427.0
HKD2_k127_5210066_1 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000001332 214.0
HKD2_k127_5217305_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 557.0
HKD2_k127_5217305_1 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 460.0
HKD2_k127_5217305_10 Putative zincin peptidase - - - 0.000000000811 65.0
HKD2_k127_5217305_2 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 454.0
HKD2_k127_5217305_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 435.0
HKD2_k127_5217305_4 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 387.0
HKD2_k127_5217305_5 Helix-hairpin-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 297.0
HKD2_k127_5217305_6 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002712 265.0
HKD2_k127_5217305_7 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000001326 149.0
HKD2_k127_5217305_8 - - - - 0.0000000000000000000000000000001994 144.0
HKD2_k127_5217305_9 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000009326 117.0
HKD2_k127_5232075_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 413.0
HKD2_k127_5232075_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000007935 138.0
HKD2_k127_5232075_2 Cell division protein FtsQ K03589 - - 0.000000000000000000000003067 117.0
HKD2_k127_5246575_0 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
HKD2_k127_5246575_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 483.0
HKD2_k127_5246575_10 - - - - 0.000000002243 65.0
HKD2_k127_5246575_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000001424 59.0
HKD2_k127_5246575_12 Domain of unknown function (DUF4340) - - - 0.00005768 57.0
HKD2_k127_5246575_2 peptidase S10 serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 466.0
HKD2_k127_5246575_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 338.0
HKD2_k127_5246575_4 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001582 284.0
HKD2_k127_5246575_5 TIGRFAM Gliding motility-associated ABC transporter ATP-binding subunit GldA K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
HKD2_k127_5246575_6 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000007024 242.0
HKD2_k127_5246575_7 transport system K01992 - - 0.00000000000000000000000000000000000000000000000000000000000633 238.0
HKD2_k127_5246575_8 Haem-degrading K11477 - - 0.0000000000000000000000000000000001323 139.0
HKD2_k127_5246575_9 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000732 138.0
HKD2_k127_5253231_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 1.318e-307 977.0
HKD2_k127_5253231_1 proline dipeptidase activity - - - 2.069e-204 645.0
HKD2_k127_5253231_10 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000303 193.0
HKD2_k127_5253231_11 Domain of unknown function (DUF4198) - - - 0.000000000000000000000000000000000000000000000201 190.0
HKD2_k127_5253231_12 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000007724 164.0
HKD2_k127_5253231_13 - - - - 0.0000000000000000000000000000000000000001124 166.0
HKD2_k127_5253231_14 lyase activity - - - 0.0000000000000000163 97.0
HKD2_k127_5253231_15 Polysaccharide deacetylase - - - 0.000000004475 63.0
HKD2_k127_5253231_16 cytochrome oxidase maturation protein cbb3-type - - - 0.00005046 57.0
HKD2_k127_5253231_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 518.0
HKD2_k127_5253231_3 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 439.0
HKD2_k127_5253231_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 398.0
HKD2_k127_5253231_5 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004319 277.0
HKD2_k127_5253231_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007868 270.0
HKD2_k127_5253231_7 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000001225 244.0
HKD2_k127_5253231_8 COG0348 Polyferredoxin - - - 0.0000000000000000000000000000000000000000000000000000001462 203.0
HKD2_k127_5253231_9 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000000000000000000000000000000002051 190.0
HKD2_k127_5299589_0 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 522.0
HKD2_k127_5299589_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 496.0
HKD2_k127_5299589_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 370.0
HKD2_k127_5299589_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 345.0
HKD2_k127_5299589_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
HKD2_k127_5299589_5 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 314.0
HKD2_k127_5299589_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
HKD2_k127_5299589_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000004382 114.0
HKD2_k127_5299589_8 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000316 75.0
HKD2_k127_5304200_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 7.567e-218 685.0
HKD2_k127_5304200_1 Reductase C-terminal K05297 - 1.18.1.1 6.235e-200 635.0
HKD2_k127_5304200_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 352.0
HKD2_k127_5304200_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 320.0
HKD2_k127_5304200_4 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000008742 142.0
HKD2_k127_5304200_5 TIGRFAM para-aminobenzoate synthase, subunit I K03342 - 2.6.1.85,4.1.3.38 0.000001997 58.0
HKD2_k127_5347209_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 5.062e-298 938.0
HKD2_k127_5347209_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.513e-219 684.0
HKD2_k127_5347209_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000008588 139.0
HKD2_k127_5347209_11 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000008951 87.0
HKD2_k127_5347209_12 Phosphopantetheine attachment site - - - 0.000000000000002828 89.0
HKD2_k127_5347209_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 572.0
HKD2_k127_5347209_3 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 486.0
HKD2_k127_5347209_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 432.0
HKD2_k127_5347209_5 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 415.0
HKD2_k127_5347209_6 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 345.0
HKD2_k127_5347209_7 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001626 272.0
HKD2_k127_5347209_8 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
HKD2_k127_5347209_9 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000827 157.0
HKD2_k127_5347463_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 1.188e-312 988.0
HKD2_k127_5347463_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000001808 233.0
HKD2_k127_5347463_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 - 1.11.1.15,2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000002215 216.0
HKD2_k127_5347463_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000001486 217.0
HKD2_k127_5347463_4 - - - - 0.00000000000000000000000000000005551 134.0
HKD2_k127_5347463_5 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.00000000000001168 82.0
HKD2_k127_5347463_6 outer membrane efflux protein - - - 0.000001327 61.0
HKD2_k127_5347463_8 PBS lyase HEAT-like repeat - - - 0.00026 53.0
HKD2_k127_5352106_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 2.95e-285 891.0
HKD2_k127_5352106_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.072e-281 885.0
HKD2_k127_5352106_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000001447 200.0
HKD2_k127_5352106_11 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000189 150.0
HKD2_k127_5352106_12 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000004493 168.0
HKD2_k127_5352106_13 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000009863 139.0
HKD2_k127_5352106_14 Biotin-requiring enzyme - - - 0.00000000000000000000000000000001572 141.0
HKD2_k127_5352106_15 Prepilin-type N-terminal cleavage methylation domain K02456,K02650 - - 0.00004134 56.0
HKD2_k127_5352106_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.948e-257 805.0
HKD2_k127_5352106_3 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 5.618e-219 713.0
HKD2_k127_5352106_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 439.0
HKD2_k127_5352106_5 Pfam:CPSase_L_chain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 445.0
HKD2_k127_5352106_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 350.0
HKD2_k127_5352106_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 353.0
HKD2_k127_5352106_8 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 324.0
HKD2_k127_5352106_9 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000968 238.0
HKD2_k127_5356381_0 Glycosyl hydrolases family 18 - - - 0.0 1281.0
HKD2_k127_5356381_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.328e-254 809.0
HKD2_k127_5356381_2 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 422.0
HKD2_k127_5356381_3 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 433.0
HKD2_k127_5356381_4 Phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000004447 189.0
HKD2_k127_5356381_5 endonuclease activity - - - 0.000000000000000000000000000000007845 131.0
HKD2_k127_5356381_6 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000002717 128.0
HKD2_k127_5356381_7 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000001433 118.0
HKD2_k127_5356381_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000003136 88.0
HKD2_k127_5364182_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 351.0
HKD2_k127_5364182_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003332 276.0
HKD2_k127_5364182_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000007536 236.0
HKD2_k127_5364182_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000004821 231.0
HKD2_k127_5364182_4 STAS domain K04749 - - 0.000000000000000000000000000000000001319 151.0
HKD2_k127_5364182_5 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.0000000000000000009243 95.0
HKD2_k127_5401520_0 Aldehyde dehydrogenase family K22187 - - 3.139e-258 811.0
HKD2_k127_5401520_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 590.0
HKD2_k127_5401520_10 - - - - 0.000000000000000000007189 108.0
HKD2_k127_5401520_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000003667 59.0
HKD2_k127_5401520_12 - - - - 0.000000064 63.0
HKD2_k127_5401520_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 582.0
HKD2_k127_5401520_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 471.0
HKD2_k127_5401520_4 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 282.0
HKD2_k127_5401520_5 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006539 274.0
HKD2_k127_5401520_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000751 260.0
HKD2_k127_5401520_7 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006647 260.0
HKD2_k127_5401520_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000009527 134.0
HKD2_k127_5401520_9 RF-1 domain K15034 - - 0.000000000000000000000000000708 128.0
HKD2_k127_5419230_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 588.0
HKD2_k127_5419230_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001169 256.0
HKD2_k127_5419230_2 isoleucine patch - - - 0.00000000000000000000000000000000000000000000000000000000002201 209.0
HKD2_k127_5419230_3 Ami_3 K01448 - 3.5.1.28 0.00000000000007097 73.0
HKD2_k127_5501209_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 625.0
HKD2_k127_5501209_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 502.0
HKD2_k127_5501209_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000008253 175.0
HKD2_k127_5501209_3 sensor histidine kinase response - - - 0.000000000000000000005741 106.0
HKD2_k127_5501209_4 4-vinyl reductase, 4VR - - - 0.0000000000000002463 87.0
HKD2_k127_5520810_0 ATPase (P-type) K01535 - 3.6.3.6 5.29e-270 855.0
HKD2_k127_5520810_1 Pirin C-terminal cupin domain K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 475.0
HKD2_k127_5520810_10 COG NOG21176 non supervised orthologous group K06975 - - 0.000000004008 63.0
HKD2_k127_5520810_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 407.0
HKD2_k127_5520810_3 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 313.0
HKD2_k127_5520810_4 radical SAM domain protein K22226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007407 265.0
HKD2_k127_5520810_5 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
HKD2_k127_5520810_6 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
HKD2_k127_5520810_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000157 145.0
HKD2_k127_5520810_8 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000004024 136.0
HKD2_k127_5520810_9 metal cluster binding K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.000000000000000443 87.0
HKD2_k127_5587984_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000001195 212.0
HKD2_k127_5587984_1 - - - - 0.0000000000000000000000000000000000000000000000003388 181.0
HKD2_k127_5609735_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001179 258.0
HKD2_k127_5609735_1 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000002012 240.0
HKD2_k127_5609735_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000005754 188.0
HKD2_k127_5609735_3 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000002764 175.0
HKD2_k127_5629783_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 403.0
HKD2_k127_5629783_1 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000001202 102.0
HKD2_k127_5636110_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.0 1051.0
HKD2_k127_5636110_1 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002397 260.0
HKD2_k127_5636110_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000008382 234.0
HKD2_k127_5636110_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000002235 119.0
HKD2_k127_5641167_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 522.0
HKD2_k127_5641167_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 440.0
HKD2_k127_5641167_2 dihydroorotate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 317.0
HKD2_k127_5641167_3 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 270.0
HKD2_k127_5641167_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000556 224.0
HKD2_k127_5641167_5 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000004176 162.0
HKD2_k127_5641167_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000008377 106.0
HKD2_k127_56729_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1198.0
HKD2_k127_56729_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 587.0
HKD2_k127_56729_10 Transcriptional regulator TetR - - - 0.000000000000000000009833 100.0
HKD2_k127_56729_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 481.0
HKD2_k127_56729_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 392.0
HKD2_k127_56729_4 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 357.0
HKD2_k127_56729_5 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002941 276.0
HKD2_k127_56729_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007835 264.0
HKD2_k127_56729_7 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000002018 223.0
HKD2_k127_56729_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000005689 211.0
HKD2_k127_56729_9 ECF sigma factor K03088 - - 0.0000000000000000000000000000005947 131.0
HKD2_k127_5674937_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 335.0
HKD2_k127_5674937_1 HypF finger K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 309.0
HKD2_k127_5674937_2 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001141 263.0
HKD2_k127_5674937_3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000000000000007005 148.0
HKD2_k127_5674937_4 GYD domain - - - 0.0000000000000000000000000008109 117.0
HKD2_k127_5692786_0 polygalacturonase activity K01184 - 3.2.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 326.0
HKD2_k127_5692786_1 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
HKD2_k127_5692786_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000001015 199.0
HKD2_k127_5705307_0 Hydrogenase formation hypA family K04654 - - 1.305e-211 660.0
HKD2_k127_5705307_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 421.0
HKD2_k127_5705307_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000003914 83.0
HKD2_k127_5705307_2 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 355.0
HKD2_k127_5705307_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 312.0
HKD2_k127_5705307_4 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001431 256.0
HKD2_k127_5705307_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.000000000000000000000000000000000000000000000001462 178.0
HKD2_k127_5705307_6 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000247 162.0
HKD2_k127_5705307_7 Domain of unknown function (DUF1508) K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000003324 127.0
HKD2_k127_5705307_8 carbon dioxide binding K04653,K04656 - - 0.000000000000000000000000000001967 123.0
HKD2_k127_5720474_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 9.087e-197 626.0
HKD2_k127_5720474_1 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 544.0
HKD2_k127_5720474_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 301.0
HKD2_k127_5720474_3 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000008668 239.0
HKD2_k127_5720474_4 - K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000002498 211.0
HKD2_k127_5720474_5 inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000003036 146.0
HKD2_k127_5745366_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 541.0
HKD2_k127_5745366_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 552.0
HKD2_k127_5745366_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 409.0
HKD2_k127_5745366_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 310.0
HKD2_k127_5745366_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 302.0
HKD2_k127_5745366_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000992 291.0
HKD2_k127_5745366_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000002781 209.0
HKD2_k127_5745366_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000007224 201.0
HKD2_k127_5745366_8 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000005887 165.0
HKD2_k127_587793_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 317.0
HKD2_k127_587793_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
HKD2_k127_587793_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000003626 245.0
HKD2_k127_587793_3 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.00000000000000000000000000000007142 128.0
HKD2_k127_587793_4 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000002707 109.0
HKD2_k127_5928207_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.477e-221 721.0
HKD2_k127_5928207_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000006162 159.0
HKD2_k127_5928207_2 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000177 139.0
HKD2_k127_5928207_3 PspC domain - - - 0.0000000001919 64.0
HKD2_k127_5928207_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000003593 63.0
HKD2_k127_5928207_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0008092 49.0
HKD2_k127_5954624_0 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 541.0
HKD2_k127_5954624_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 430.0
HKD2_k127_5954624_2 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HKD2_k127_595729_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 551.0
HKD2_k127_595729_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 469.0
HKD2_k127_595729_2 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000008602 264.0
HKD2_k127_595729_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004762 265.0
HKD2_k127_595729_4 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000003714 140.0
HKD2_k127_595729_5 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000002434 131.0
HKD2_k127_595729_6 - - - - 0.00000000000000000000000002242 122.0
HKD2_k127_595729_7 - - - - 0.000000000002537 79.0
HKD2_k127_595729_8 PFAM Late competence development protein ComFB K02241 - - 0.000000008524 67.0
HKD2_k127_5958763_0 NAD synthase K01916 - 6.3.1.5 3.881e-207 661.0
HKD2_k127_5958763_1 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005087 263.0
HKD2_k127_5958763_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0002695 49.0
HKD2_k127_5958763_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000009021 213.0
HKD2_k127_5958763_3 acr, cog1993 K09137 - - 0.0000000000000000000000000000000000000000000000001522 179.0
HKD2_k127_5958763_4 PFAM peptidase M13 K01415 - 3.4.24.71 0.0000000000000000000000000000000000001126 149.0
HKD2_k127_5958763_5 Thioesterase superfamily - - - 0.0000000000000000000000000000005458 142.0
HKD2_k127_5958763_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000403 136.0
HKD2_k127_5958763_7 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000001225 116.0
HKD2_k127_5958763_8 4Fe-4S single cluster domain K07001 - - 0.0000000000000000000000008236 119.0
HKD2_k127_5958763_9 Putative phosphatase (DUF442) - - - 0.00000000000000000003649 96.0
HKD2_k127_6021347_0 Voltage gated chloride channel K03281 - - 4.177e-211 674.0
HKD2_k127_6021347_1 AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 541.0
HKD2_k127_6021347_2 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 389.0
HKD2_k127_6021347_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 349.0
HKD2_k127_6021347_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001706 283.0
HKD2_k127_6021347_5 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000189 284.0
HKD2_k127_6021347_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000002742 146.0
HKD2_k127_6021347_7 TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000005625 126.0
HKD2_k127_6021347_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00008408 53.0
HKD2_k127_6030423_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1034.0
HKD2_k127_6030423_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 6.882e-267 833.0
HKD2_k127_6030423_10 PFAM AsmA family K07289 - - 0.0000000000000000058 96.0
HKD2_k127_6030423_11 CDP-alcohol phosphatidyltransferase K07291 - 2.7.8.34 0.00000006234 64.0
HKD2_k127_6030423_2 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 475.0
HKD2_k127_6030423_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000006548 184.0
HKD2_k127_6030423_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000004219 171.0
HKD2_k127_6030423_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000002676 173.0
HKD2_k127_6030423_6 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000003403 152.0
HKD2_k127_6030423_7 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000009766 141.0
HKD2_k127_6030423_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000001766 132.0
HKD2_k127_6030423_9 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000004004 123.0
HKD2_k127_6077571_0 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 548.0
HKD2_k127_6077571_1 TIGRFAM acetoacetyl-CoA reductase K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 311.0
HKD2_k127_6077571_2 TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000005574 193.0
HKD2_k127_6077571_3 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000002035 88.0
HKD2_k127_6077571_4 Phasin protein - - - 0.00005104 51.0
HKD2_k127_6211459_0 PQQ enzyme repeat K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 578.0
HKD2_k127_6211459_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 475.0
HKD2_k127_6211459_2 signal transduction histidine kinase K13587 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 334.0
HKD2_k127_6211459_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000008285 246.0
HKD2_k127_6211459_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000006119 187.0
HKD2_k127_6211459_6 HNH nucleases - - - 0.00000000000005419 80.0
HKD2_k127_62305_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 9.315e-285 894.0
HKD2_k127_62305_1 Copper chaperone PCu(A)C K03619,K07152,K09796 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.0000000000000000000000000000000000000000000000000000001494 201.0
HKD2_k127_6388028_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 538.0
HKD2_k127_6388028_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 526.0
HKD2_k127_6388028_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000006639 96.0
HKD2_k127_6388028_11 Preprotein translocase SecG subunit K03075 - - 0.0002626 45.0
HKD2_k127_6388028_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 491.0
HKD2_k127_6388028_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 478.0
HKD2_k127_6388028_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000009118 248.0
HKD2_k127_6388028_5 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000003244 210.0
HKD2_k127_6388028_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000002099 201.0
HKD2_k127_6388028_7 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000117 168.0
HKD2_k127_6388028_8 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000006716 161.0
HKD2_k127_6388028_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000006952 153.0
HKD2_k127_6403468_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 608.0
HKD2_k127_6403468_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000004695 67.0
HKD2_k127_6423223_0 Bacterial membrane protein YfhO - - - 2.765e-227 728.0
HKD2_k127_6423223_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
HKD2_k127_6423223_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 357.0
HKD2_k127_6423223_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000006727 199.0
HKD2_k127_6423223_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000002263 141.0
HKD2_k127_6423223_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000002718 98.0
HKD2_k127_6423223_6 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000003085 69.0
HKD2_k127_6440482_0 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003343 288.0
HKD2_k127_6440482_1 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000001041 119.0
HKD2_k127_6440482_2 RDD family - - - 0.0000005195 59.0
HKD2_k127_6448998_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1045.0
HKD2_k127_6448998_1 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 6.903e-200 635.0
HKD2_k127_6448998_10 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003873 247.0
HKD2_k127_6448998_11 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000848 241.0
HKD2_k127_6448998_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000001216 238.0
HKD2_k127_6448998_13 lipoprotein localization to outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
HKD2_k127_6448998_14 HAD-hyrolase-like K06019 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001617 248.0
HKD2_k127_6448998_15 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000001128 205.0
HKD2_k127_6448998_16 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000004147 182.0
HKD2_k127_6448998_17 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.00000000000000000000000000000000000004493 156.0
HKD2_k127_6448998_18 NUDIX domain - - - 0.0000000000000000000000000000000000003623 151.0
HKD2_k127_6448998_19 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000003646 128.0
HKD2_k127_6448998_2 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 617.0
HKD2_k127_6448998_20 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000437 117.0
HKD2_k127_6448998_21 Helicase conserved C-terminal domain - - - 0.00000000000000001265 98.0
HKD2_k127_6448998_22 Regulatory protein, FmdB family - - - 0.00000009726 65.0
HKD2_k127_6448998_23 SnoaL-like domain - - - 0.00000246 60.0
HKD2_k127_6448998_24 PFAM PEGA domain - - - 0.00003903 56.0
HKD2_k127_6448998_3 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 518.0
HKD2_k127_6448998_4 DNA restriction-modification system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 443.0
HKD2_k127_6448998_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 409.0
HKD2_k127_6448998_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 287.0
HKD2_k127_6448998_7 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004215 284.0
HKD2_k127_6448998_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008452 287.0
HKD2_k127_6448998_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002606 273.0
HKD2_k127_6455955_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 420.0
HKD2_k127_6455955_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 336.0
HKD2_k127_6455955_2 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 319.0
HKD2_k127_6455955_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000001403 216.0
HKD2_k127_6455955_4 HEAT repeats - - - 0.0000000000000002715 93.0
HKD2_k127_6455955_5 - - - - 0.000000000000000345 86.0
HKD2_k127_6458924_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000008039 252.0
HKD2_k127_6458924_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000001298 179.0
HKD2_k127_6458924_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000001389 99.0
HKD2_k127_6458924_3 HAMP domain, Methyl-accepting chemotaxis protein (MCP) signaling domain K05875 - - 0.0000000000000002649 83.0
HKD2_k127_647331_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.735e-269 840.0
HKD2_k127_647331_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.845e-213 684.0
HKD2_k127_647331_10 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 382.0
HKD2_k127_647331_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 361.0
HKD2_k127_647331_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 334.0
HKD2_k127_647331_13 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 321.0
HKD2_k127_647331_14 GIY-YIG type nucleases (URI domain) K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001476 295.0
HKD2_k127_647331_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008831 288.0
HKD2_k127_647331_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000008236 284.0
HKD2_k127_647331_17 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003144 268.0
HKD2_k127_647331_18 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001446 283.0
HKD2_k127_647331_19 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001058 265.0
HKD2_k127_647331_2 TonB dependent receptor K16091 - - 1.094e-202 658.0
HKD2_k127_647331_20 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001416 260.0
HKD2_k127_647331_21 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001647 252.0
HKD2_k127_647331_22 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000016 240.0
HKD2_k127_647331_23 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000001096 196.0
HKD2_k127_647331_24 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000008101 207.0
HKD2_k127_647331_25 - - - - 0.000000000000000000000000000000000000000000000002704 191.0
HKD2_k127_647331_26 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000003764 175.0
HKD2_k127_647331_27 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000000008599 163.0
HKD2_k127_647331_28 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000002244 157.0
HKD2_k127_647331_29 Serine hydrolase (FSH1) - - - 0.0000000000000009873 82.0
HKD2_k127_647331_3 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 524.0
HKD2_k127_647331_30 Copper binding proteins, plastocyanin/azurin family - - - 0.000000002872 64.0
HKD2_k127_647331_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 520.0
HKD2_k127_647331_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 515.0
HKD2_k127_647331_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 494.0
HKD2_k127_647331_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 460.0
HKD2_k127_647331_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 402.0
HKD2_k127_647331_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 377.0
HKD2_k127_648450_0 PFAM Uncharacterised protein family (UPF0236) - - - 6.578e-203 641.0
HKD2_k127_648450_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000004243 128.0
HKD2_k127_6485534_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 311.0
HKD2_k127_6485534_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000001205 153.0
HKD2_k127_6487757_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 580.0
HKD2_k127_6487757_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
HKD2_k127_6487757_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000004638 166.0
HKD2_k127_6487757_3 - - - - 0.0001919 44.0
HKD2_k127_6489252_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.863e-246 776.0
HKD2_k127_6489252_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 620.0
HKD2_k127_6489252_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 353.0
HKD2_k127_6489252_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 325.0
HKD2_k127_6489252_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000008276 274.0
HKD2_k127_6489252_5 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000004175 257.0
HKD2_k127_6489252_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000001528 211.0
HKD2_k127_6489252_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000007014 52.0
HKD2_k127_6489252_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0001277 49.0
HKD2_k127_6492191_0 membrane organization - - - 3.385e-232 751.0
HKD2_k127_6492191_1 xanthine dehydrogenase activity K07303 - 1.3.99.16 2.035e-200 648.0
HKD2_k127_6492191_10 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002116 230.0
HKD2_k127_6492191_11 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000004629 201.0
HKD2_k127_6492191_12 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000001082 116.0
HKD2_k127_6492191_13 membrane - - - 0.0000000000000000000003783 101.0
HKD2_k127_6492191_2 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 533.0
HKD2_k127_6492191_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 405.0
HKD2_k127_6492191_4 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 406.0
HKD2_k127_6492191_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 400.0
HKD2_k127_6492191_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 374.0
HKD2_k127_6492191_7 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 291.0
HKD2_k127_6492191_8 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002994 282.0
HKD2_k127_6492191_9 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000005071 244.0
HKD2_k127_6510703_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 613.0
HKD2_k127_6510703_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 569.0
HKD2_k127_6510703_10 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000004792 198.0
HKD2_k127_6510703_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000003641 168.0
HKD2_k127_6510703_12 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000002003 141.0
HKD2_k127_6510703_13 COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000009264 111.0
HKD2_k127_6510703_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000002456 95.0
HKD2_k127_6510703_15 lysyltransferase activity - - - 0.00000000000000001538 94.0
HKD2_k127_6510703_17 - - - - 0.0000000000001048 83.0
HKD2_k127_6510703_2 Semialdehyde dehydrogenase, NAD binding domain K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 394.0
HKD2_k127_6510703_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 370.0
HKD2_k127_6510703_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 358.0
HKD2_k127_6510703_5 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 350.0
HKD2_k127_6510703_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 334.0
HKD2_k127_6510703_7 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 324.0
HKD2_k127_6510703_8 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
HKD2_k127_6510703_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001575 297.0
HKD2_k127_6513896_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 269.0
HKD2_k127_6513896_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000002383 150.0
HKD2_k127_6513896_2 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.0000001969 61.0
HKD2_k127_6517035_0 - - - - 0.00000000000000000000000000000000000000000000000000004322 202.0
HKD2_k127_6517035_1 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000002244 158.0
HKD2_k127_6517035_12 - - - - 0.0000001103 57.0
HKD2_k127_6517035_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000004761 166.0
HKD2_k127_6517035_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000008793 165.0
HKD2_k127_6517035_5 - - - - 0.000000000000000000000000000001337 127.0
HKD2_k127_6517035_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000006503 100.0
HKD2_k127_6517035_8 Protein of unknown function (DUF983) - - - 0.0000000000000006165 85.0
HKD2_k127_6517035_9 SdpI/YhfL protein family - - - 0.0000000002642 66.0
HKD2_k127_6517392_0 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 528.0
HKD2_k127_6517392_1 Alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 473.0
HKD2_k127_6517392_2 amine dehydrogenase activity K17285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 386.0
HKD2_k127_6517392_3 CGNR zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
HKD2_k127_6517392_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000459 199.0
HKD2_k127_6517392_5 - - - - 0.00000000000000000000000000000000000000000000000000001857 205.0
HKD2_k127_6540140_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.903e-319 1003.0
HKD2_k127_6540140_1 Uncharacterized protein family (UPF0051) K09014 - - 1.477e-260 808.0
HKD2_k127_6540140_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000001754 208.0
HKD2_k127_6540140_11 - - - - 0.00000000000000000000000000000000000000000000000000000008066 214.0
HKD2_k127_6540140_12 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000003931 200.0
HKD2_k127_6540140_13 HTH domain - - - 0.0000000000000000000000000000000000000000000000009272 183.0
HKD2_k127_6540140_14 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000002256 151.0
HKD2_k127_6540140_15 FAD binding domain K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000003398 156.0
HKD2_k127_6540140_16 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000004709 160.0
HKD2_k127_6540140_17 Matrixin - - - 0.00000000000000000000000000001455 128.0
HKD2_k127_6540140_18 metal-sulfur cluster biosynthetic - - - 0.0000000000000000000000000000584 119.0
HKD2_k127_6540140_19 Protein conserved in bacteria - - - 0.0000000000000000004672 91.0
HKD2_k127_6540140_2 Aminotransferase class-III K00827 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0008144,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0016020,GO:0019842,GO:0030170,GO:0031090,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050896,GO:0070279,GO:0097159,GO:0098588,GO:0098805,GO:1901363 2.6.1.40,2.6.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 525.0
HKD2_k127_6540140_20 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K07033,K09015 - - 0.00000000009258 70.0
HKD2_k127_6540140_3 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 386.0
HKD2_k127_6540140_4 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 390.0
HKD2_k127_6540140_5 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
HKD2_k127_6540140_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 317.0
HKD2_k127_6540140_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 302.0
HKD2_k127_6540140_8 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
HKD2_k127_6540140_9 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000001527 211.0
HKD2_k127_6541089_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 513.0
HKD2_k127_6541089_1 RDD family K06384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 337.0
HKD2_k127_6541089_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000002094 188.0
HKD2_k127_6541089_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000001401 74.0
HKD2_k127_6541089_4 Condensation domain - - - 0.0008789 47.0
HKD2_k127_6552560_0 PFAM Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 451.0
HKD2_k127_6552560_1 Bacterial dnaA protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004626 283.0
HKD2_k127_6552560_2 Integrase core domain K07497 - - 0.00000000000004821 72.0
HKD2_k127_6563047_0 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 448.0
HKD2_k127_6563047_1 Bacterial dnaA protein K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 409.0
HKD2_k127_6563047_10 PFAM CheW domain protein K03408 - - 0.000000000000000000000000004393 115.0
HKD2_k127_6563047_11 Roadblock/LC7 domain - - - 0.00000000000009194 84.0
HKD2_k127_6563047_13 peptidyl-tyrosine sulfation - - - 0.00001202 58.0
HKD2_k127_6563047_14 Tetratricopeptide repeats - - - 0.00001363 56.0
HKD2_k127_6563047_15 Two component signalling adaptor domain K03408 - - 0.0007053 52.0
HKD2_k127_6563047_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 295.0
HKD2_k127_6563047_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004545 297.0
HKD2_k127_6563047_4 Small GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001664 276.0
HKD2_k127_6563047_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 266.0
HKD2_k127_6563047_6 Chemotaxis K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000001839 183.0
HKD2_k127_6563047_7 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000001351 156.0
HKD2_k127_6563047_8 - - - - 0.000000000000000000000000000000004122 139.0
HKD2_k127_6563047_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000004273 140.0
HKD2_k127_6563979_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003612 304.0
HKD2_k127_6563979_1 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005241 274.0
HKD2_k127_6563979_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000007134 230.0
HKD2_k127_6563979_4 Polysaccharide biosynthesis protein - - - 0.000000000000000155 94.0
HKD2_k127_6563979_5 Glycosyl transferase family 2 - - - 0.000000000000001489 91.0
HKD2_k127_6563979_6 Glycosyltransferase like family 2 - - - 0.00000000006878 75.0
HKD2_k127_6563979_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000001027 55.0
HKD2_k127_6569475_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5e-324 1007.0
HKD2_k127_6569475_1 belongs to the aldehyde dehydrogenase family K00138 - - 5.501e-266 830.0
HKD2_k127_6569475_2 Malate synthase K01638 - 2.3.3.9 7.262e-231 736.0
HKD2_k127_6569475_3 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 596.0
HKD2_k127_6569475_4 TIGRFAM acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 320.0
HKD2_k127_6569475_5 transcription factor binding K21405 - - 0.00000000000000000000000000000000000000000000000000000003813 207.0
HKD2_k127_6569475_6 Protein of unknown function (DUF779) K09959 - - 0.000000000000000000000000000000000000000000000005732 194.0
HKD2_k127_6569475_7 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000004068 171.0
HKD2_k127_6577319_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1187.0
HKD2_k127_6577319_1 ACT domain K12524 - 1.1.1.3,2.7.2.4 1.488e-278 889.0
HKD2_k127_6577319_10 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 316.0
HKD2_k127_6577319_11 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 284.0
HKD2_k127_6577319_12 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000001436 201.0
HKD2_k127_6577319_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000009404 106.0
HKD2_k127_6577319_14 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000001507 100.0
HKD2_k127_6577319_15 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000001887 106.0
HKD2_k127_6577319_16 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000369 106.0
HKD2_k127_6577319_17 - - - - 0.0000000003067 70.0
HKD2_k127_6577319_18 KaiC - - - 0.00001125 58.0
HKD2_k127_6577319_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00007909 55.0
HKD2_k127_6577319_2 Peptidase family M3 K08602 - - 4.788e-230 726.0
HKD2_k127_6577319_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 555.0
HKD2_k127_6577319_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 544.0
HKD2_k127_6577319_5 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 535.0
HKD2_k127_6577319_6 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 418.0
HKD2_k127_6577319_7 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 388.0
HKD2_k127_6577319_8 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 343.0
HKD2_k127_6577319_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
HKD2_k127_6624730_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 311.0
HKD2_k127_6624730_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000006319 184.0
HKD2_k127_6624730_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000002131 160.0
HKD2_k127_6624730_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000004674 109.0
HKD2_k127_6624730_4 ThiS family - - - 0.000000000000002728 78.0
HKD2_k127_6651428_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.763e-280 883.0
HKD2_k127_6651428_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 566.0
HKD2_k127_6651428_10 - - - - 0.000000000000000002822 94.0
HKD2_k127_6651428_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 500.0
HKD2_k127_6651428_3 AMIN domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 422.0
HKD2_k127_6651428_4 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 383.0
HKD2_k127_6651428_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 312.0
HKD2_k127_6651428_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000321 271.0
HKD2_k127_6651428_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000009884 117.0
HKD2_k127_6651428_8 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000004003 106.0
HKD2_k127_6651428_9 Fimbrial assembly protein (PilN) - - - 0.0000000000000000000002997 101.0
HKD2_k127_6690022_0 Amidohydrolase family K00200 - 1.2.7.12 1.001e-276 859.0
HKD2_k127_6690022_1 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 9.529e-209 668.0
HKD2_k127_6690022_10 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003186 264.0
HKD2_k127_6690022_11 CO2 hydration protein (ChpXY) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002528 243.0
HKD2_k127_6690022_12 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008108 240.0
HKD2_k127_6690022_13 4Fe-4S binding domain K05524 - - 0.00000000000000000000000000000000000000008929 152.0
HKD2_k127_6690022_14 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0044237,GO:0044281 2.3.1.101 0.00000000000000000000002488 101.0
HKD2_k127_6690022_15 PFAM molydopterin dinucleotide-binding region K00203,K00336 - 1.2.7.12,1.6.5.3 0.0000000000000003013 85.0
HKD2_k127_6690022_2 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 526.0
HKD2_k127_6690022_3 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 454.0
HKD2_k127_6690022_4 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 431.0
HKD2_k127_6690022_5 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 404.0
HKD2_k127_6690022_6 RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 351.0
HKD2_k127_6690022_7 Hydantoinase/oxoprolinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 348.0
HKD2_k127_6690022_8 GXGXG motif K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000089 273.0
HKD2_k127_6690022_9 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001255 274.0
HKD2_k127_6723700_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 507.0
HKD2_k127_6723700_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 483.0
HKD2_k127_6723700_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000003071 258.0
HKD2_k127_6723700_3 cheY-homologous receiver domain - - - 0.0000000000000000000004966 105.0
HKD2_k127_6723700_4 Sortilin, neurotensin receptor 3, - - - 0.000000000002139 76.0
HKD2_k127_6744050_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.408e-250 790.0
HKD2_k127_6744050_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 518.0
HKD2_k127_6744050_10 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 337.0
HKD2_k127_6744050_11 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002168 284.0
HKD2_k127_6744050_12 extracellular polysaccharide biosynthetic process K13582 - - 0.000000000000000000000000000000000000000000000000000000000000000001374 238.0
HKD2_k127_6744050_13 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000002686 243.0
HKD2_k127_6744050_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000009204 194.0
HKD2_k127_6744050_15 creatininase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000009798 175.0
HKD2_k127_6744050_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000001655 125.0
HKD2_k127_6744050_17 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000005819 115.0
HKD2_k127_6744050_18 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000005093 59.0
HKD2_k127_6744050_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 461.0
HKD2_k127_6744050_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 430.0
HKD2_k127_6744050_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 421.0
HKD2_k127_6744050_5 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 398.0
HKD2_k127_6744050_6 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 389.0
HKD2_k127_6744050_7 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 382.0
HKD2_k127_6744050_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 364.0
HKD2_k127_6744050_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 361.0
HKD2_k127_6832813_0 HELICc2 K03722 - 3.6.4.12 9.326e-274 866.0
HKD2_k127_6832813_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 428.0
HKD2_k127_6832813_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003103 261.0
HKD2_k127_6832813_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000406 261.0
HKD2_k127_6832813_4 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000001559 244.0
HKD2_k127_6832813_5 - - - - 0.00000000000000000000000000103 125.0
HKD2_k127_6838386_0 ligase activity - - - 0.00000000000000000000000000000000000000000000001092 183.0
HKD2_k127_6838386_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000209 178.0
HKD2_k127_6898316_0 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.0000000000000000000000000000000000000000000000000000000000001616 232.0
HKD2_k127_6898316_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000002492 203.0
HKD2_k127_6898316_2 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000257 158.0
HKD2_k127_6898316_3 Cold shock protein K03704 - - 0.000000000000000000000000002829 113.0
HKD2_k127_6898316_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000006456 111.0
HKD2_k127_6898316_5 YceI-like domain - - - 0.000000002596 66.0
HKD2_k127_6898316_6 Tfp pilus assembly protein FimT - - - 0.000001406 57.0
HKD2_k127_6898316_7 Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator K02584 - - 0.00002026 57.0
HKD2_k127_7018951_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 447.0
HKD2_k127_7018951_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 411.0
HKD2_k127_7018951_2 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009066 236.0
HKD2_k127_7018951_3 - - - - 0.000000000000000000000000000000000000009919 163.0
HKD2_k127_7018951_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000002015 132.0
HKD2_k127_7018951_5 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002462 136.0
HKD2_k127_7018951_6 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000006224 112.0
HKD2_k127_7018951_7 Transposase IS200 like K07491 - - 0.0000000000000000002114 97.0
HKD2_k127_7018951_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000003504 59.0
HKD2_k127_702012_0 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 315.0
HKD2_k127_702012_1 PFAM MmgE PrpD - - - 0.00000000000000000000000000000000000000000000002093 183.0
HKD2_k127_7192104_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006016 287.0
HKD2_k127_7192104_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001058 265.0
HKD2_k127_7192104_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004347 247.0
HKD2_k127_7192104_3 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000136 214.0
HKD2_k127_7192104_4 light absorption - - - 0.00000000000000000000000000000000006673 139.0
HKD2_k127_7192104_5 - - - - 0.00000000000308 77.0
HKD2_k127_719511_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 507.0
HKD2_k127_719511_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 462.0
HKD2_k127_719511_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000002039 89.0
HKD2_k127_719511_11 Ribosomal protein L36 K02919 - - 0.000000000000003766 78.0
HKD2_k127_719511_12 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000003123 74.0
HKD2_k127_719511_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 312.0
HKD2_k127_719511_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
HKD2_k127_719511_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000001576 241.0
HKD2_k127_719511_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000005689 209.0
HKD2_k127_719511_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000001911 206.0
HKD2_k127_719511_7 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000002912 192.0
HKD2_k127_719511_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000001104 176.0
HKD2_k127_719511_9 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000225 156.0
HKD2_k127_7202083_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000105 164.0
HKD2_k127_7202083_1 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000000000002982 172.0
HKD2_k127_7251290_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 372.0
HKD2_k127_7251290_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 318.0
HKD2_k127_7251290_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
HKD2_k127_7251290_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001072 276.0
HKD2_k127_7251290_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000001235 231.0
HKD2_k127_7251290_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000005655 169.0
HKD2_k127_7251290_6 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000001992 162.0
HKD2_k127_7251290_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.00000000000000000000000000000000577 146.0
HKD2_k127_7251290_8 - - - - 0.0000000000000001411 91.0
HKD2_k127_7251290_9 - - - - 0.000000000006239 77.0
HKD2_k127_7277919_0 filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 525.0
HKD2_k127_7277919_1 Belongs to the GcvT family K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 443.0
HKD2_k127_7277919_2 PFAM PIN domain - - - 0.0000000000000000000000000000004992 130.0
HKD2_k127_7277919_3 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000000000000004723 111.0
HKD2_k127_7277919_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000001073 91.0
HKD2_k127_7332227_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 415.0
HKD2_k127_7332227_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
HKD2_k127_7332227_2 - - - - 0.00000223 53.0
HKD2_k127_7354468_0 AcrB/AcrD/AcrF family - - - 0.0 1062.0
HKD2_k127_7354468_1 Putative ABC exporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 303.0
HKD2_k127_7354468_2 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
HKD2_k127_7354468_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000006031 159.0
HKD2_k127_7354468_4 - - - - 0.000000000000000000000000000000000000008534 150.0
HKD2_k127_7354468_5 - - - - 0.00000000000000000000000000000002491 147.0
HKD2_k127_7354468_6 Outer membrane efflux protein - - - 0.00000000000000000000008451 110.0
HKD2_k127_7354468_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000004917 64.0
HKD2_k127_7354468_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000848 52.0
HKD2_k127_7364915_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 522.0
HKD2_k127_7449264_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 467.0
HKD2_k127_7449264_1 Preprotein translocase SecG subunit K03075 - - 0.0000000000001712 76.0
HKD2_k127_7500263_0 tRNA synthetases class I (M) K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 528.0
HKD2_k127_7500263_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 452.0
HKD2_k127_7500263_2 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 340.0
HKD2_k127_7500263_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000008252 183.0
HKD2_k127_7500263_4 heme binding K21471 - - 0.0000000000000000000000000000000000000000339 164.0
HKD2_k127_7500263_5 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0000000000000000000000000000000515 130.0
HKD2_k127_7500263_6 nucleotidyltransferase activity - - - 0.00000000000000002251 92.0
HKD2_k127_76358_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.394e-288 925.0
HKD2_k127_76358_1 ABC transporter K06020 - 3.6.3.25 1.717e-246 773.0
HKD2_k127_76358_10 Redoxin - - - 0.0002123 47.0
HKD2_k127_76358_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 588.0
HKD2_k127_76358_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 475.0
HKD2_k127_76358_4 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 472.0
HKD2_k127_76358_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 445.0
HKD2_k127_76358_6 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 431.0
HKD2_k127_76358_7 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 422.0
HKD2_k127_76358_8 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000001551 133.0
HKD2_k127_76358_9 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000004695 102.0
HKD2_k127_7637808_0 best DB hits BLAST gb AAD45539.1 - - - 0.0000000000000000000000000000000000000000000000000000000004465 219.0
HKD2_k127_7663251_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.741e-252 786.0
HKD2_k127_7663251_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 446.0
HKD2_k127_7663251_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 297.0
HKD2_k127_7663251_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 304.0
HKD2_k127_7663251_4 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 286.0
HKD2_k127_7663251_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000005652 239.0
HKD2_k127_7663251_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000004951 230.0
HKD2_k127_7663251_7 NUDIX domain - - - 0.000000000000000000000000000000000000000008117 168.0
HKD2_k127_7663251_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000008144 151.0
HKD2_k127_7663251_9 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000001897 53.0
HKD2_k127_7666858_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 584.0
HKD2_k127_7666858_1 MMPL family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 467.0
HKD2_k127_7666858_10 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001752 285.0
HKD2_k127_7666858_11 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000004315 267.0
HKD2_k127_7666858_12 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.0000000000000000000000000000000000000000000000000000000000001124 231.0
HKD2_k127_7666858_13 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000634 219.0
HKD2_k127_7666858_14 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000009377 224.0
HKD2_k127_7666858_15 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000001515 213.0
HKD2_k127_7666858_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000004471 195.0
HKD2_k127_7666858_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000006351 190.0
HKD2_k127_7666858_18 alpha beta - - - 0.00000000000000000000000000000000000000000000000002857 198.0
HKD2_k127_7666858_19 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000965 165.0
HKD2_k127_7666858_2 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 474.0
HKD2_k127_7666858_20 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001116 145.0
HKD2_k127_7666858_21 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000001514 138.0
HKD2_k127_7666858_22 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.000000000000000000000000000463 128.0
HKD2_k127_7666858_23 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000000001435 113.0
HKD2_k127_7666858_24 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000006712 98.0
HKD2_k127_7666858_25 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000001592 83.0
HKD2_k127_7666858_26 - - - - 0.00000000007909 69.0
HKD2_k127_7666858_27 Transposase - - - 0.00002707 56.0
HKD2_k127_7666858_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 425.0
HKD2_k127_7666858_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
HKD2_k127_7666858_5 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 347.0
HKD2_k127_7666858_6 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 331.0
HKD2_k127_7666858_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 299.0
HKD2_k127_7666858_8 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 308.0
HKD2_k127_7666858_9 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001839 300.0
HKD2_k127_7675638_0 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 310.0
HKD2_k127_7675638_1 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003284 225.0
HKD2_k127_7676130_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 601.0
HKD2_k127_7676130_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 468.0
HKD2_k127_7676130_10 Pterin 4 alpha carbinolamine dehydratase K01724,K11991 - 3.5.4.33,4.2.1.96 0.00000000000000000000000000000000000000000000003427 172.0
HKD2_k127_7676130_11 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000459 149.0
HKD2_k127_7676130_12 GXGXG motif K00202 - 1.2.7.12 0.000000000000000000000000000000007636 130.0
HKD2_k127_7676130_13 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000002619 137.0
HKD2_k127_7676130_14 - K01633,K07144 - 1.13.11.81,2.7.4.31,4.1.2.25,5.1.99.8 0.0000000000000000000000001128 115.0
HKD2_k127_7676130_15 4-HFC-P synthase - - - 0.0000000000000000000006809 105.0
HKD2_k127_7676130_16 EthD domain - - - 0.000000000000006586 89.0
HKD2_k127_7676130_17 EthD domain - - - 0.000000000000564 82.0
HKD2_k127_7676130_2 sensor diguanylate cyclase phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 467.0
HKD2_k127_7676130_3 Anthranilate synthase component I, N terminal region K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 432.0
HKD2_k127_7676130_4 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 356.0
HKD2_k127_7676130_5 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0044424,GO:0044464,GO:0071704 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 311.0
HKD2_k127_7676130_6 GXGXG motif K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003456 278.0
HKD2_k127_7676130_7 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000007374 259.0
HKD2_k127_7676130_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000841 257.0
HKD2_k127_7676130_9 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000002664 256.0
HKD2_k127_7685778_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000557 277.0
HKD2_k127_7685778_1 luxR family - - - 0.0000000000000000000000000000000000000000974 156.0
HKD2_k127_7688519_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 1.262e-212 691.0
HKD2_k127_7688519_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 544.0
HKD2_k127_7688519_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 448.0
HKD2_k127_7688519_3 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000004684 229.0
HKD2_k127_7688519_4 Tellurite resistance protein TehB - - - 0.000000000000000000000002101 109.0
HKD2_k127_7722905_0 PglZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 614.0
HKD2_k127_7722905_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 547.0
HKD2_k127_7722905_10 Glycosyl transferases group 1 - - - 0.000000000006261 78.0
HKD2_k127_7722905_11 ribosomal protein - - - 0.00000007876 59.0
HKD2_k127_7722905_2 tRNA synthetases class I (W and Y) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 401.0
HKD2_k127_7722905_3 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 334.0
HKD2_k127_7722905_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 313.0
HKD2_k127_7722905_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 312.0
HKD2_k127_7722905_6 4Fe-4S single cluster domain K07001 - - 0.0000000000000000000000000000000000000000000000000000000000001601 227.0
HKD2_k127_7722905_7 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000002383 199.0
HKD2_k127_7722905_8 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000003591 186.0
HKD2_k127_7722905_9 glycosyl transferase group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000005504 182.0
HKD2_k127_7733412_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1016.0
HKD2_k127_7733412_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.973e-237 748.0
HKD2_k127_7733412_10 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 358.0
HKD2_k127_7733412_11 Glucose inhibited division protein A K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 303.0
HKD2_k127_7733412_12 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 292.0
HKD2_k127_7733412_13 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004873 280.0
HKD2_k127_7733412_14 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002016 252.0
HKD2_k127_7733412_15 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000001288 223.0
HKD2_k127_7733412_16 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000001213 198.0
HKD2_k127_7733412_17 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000009337 190.0
HKD2_k127_7733412_18 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000001827 180.0
HKD2_k127_7733412_19 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000008147 181.0
HKD2_k127_7733412_2 ABC transporter transmembrane region - - - 3.934e-228 722.0
HKD2_k127_7733412_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000003736 179.0
HKD2_k127_7733412_21 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000027 173.0
HKD2_k127_7733412_22 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000001411 163.0
HKD2_k127_7733412_23 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000001639 165.0
HKD2_k127_7733412_24 Methyltransferase domain - - - 0.000000000000000000000000000000000000002702 161.0
HKD2_k127_7733412_25 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000002222 150.0
HKD2_k127_7733412_26 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000002633 151.0
HKD2_k127_7733412_27 - - - - 0.0000000000000000000000004587 123.0
HKD2_k127_7733412_29 - - - - 0.00000000000000000005474 92.0
HKD2_k127_7733412_3 Insulinase (Peptidase family M16) K07263 - - 3.738e-201 666.0
HKD2_k127_7733412_30 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000005007 91.0
HKD2_k127_7733412_31 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000005231 93.0
HKD2_k127_7733412_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000001181 90.0
HKD2_k127_7733412_34 AntiSigma factor - GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009593,GO:0009628,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032502,GO:0042221,GO:0043167,GO:0043169,GO:0043934,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051606,GO:0051775,GO:0051776,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000003559 55.0
HKD2_k127_7733412_35 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0004719 48.0
HKD2_k127_7733412_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 595.0
HKD2_k127_7733412_5 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 566.0
HKD2_k127_7733412_6 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 579.0
HKD2_k127_7733412_7 Histidine kinase K01768,K02482,K02660,K03406,K05874,K07315,K10819,K11525,K11617 - 2.7.13.3,3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 468.0
HKD2_k127_7733412_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 443.0
HKD2_k127_7733412_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 354.0
HKD2_k127_7739139_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 313.0
HKD2_k127_7739139_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000003418 197.0
HKD2_k127_7739139_2 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000004168 192.0
HKD2_k127_7739139_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001026 182.0
HKD2_k127_7780035_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 490.0
HKD2_k127_7780035_1 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 420.0
HKD2_k127_7780035_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000001455 267.0
HKD2_k127_7780035_3 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000004075 91.0
HKD2_k127_7780035_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000001611 74.0
HKD2_k127_7780035_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000371 69.0
HKD2_k127_77948_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 517.0
HKD2_k127_77948_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 513.0
HKD2_k127_77948_10 NAD-dependent epimerase dehydratase - - - 0.000000000000001558 89.0
HKD2_k127_77948_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 374.0
HKD2_k127_77948_3 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 358.0
HKD2_k127_77948_4 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002693 258.0
HKD2_k127_77948_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000003842 243.0
HKD2_k127_77948_6 - - - - 0.00000000000000000000000000000000000000000000000185 179.0
HKD2_k127_77948_7 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.0000000000000000000000000000001086 130.0
HKD2_k127_77948_8 - - - - 0.000000000000000000000000001821 128.0
HKD2_k127_77948_9 - - - - 0.000000000000000000008409 93.0
HKD2_k127_7795711_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.549e-255 804.0
HKD2_k127_7795711_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 9.041e-237 752.0
HKD2_k127_7795711_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 598.0
HKD2_k127_7795711_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 346.0
HKD2_k127_7795711_4 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000003899 274.0
HKD2_k127_7795711_5 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000005022 168.0
HKD2_k127_7795711_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000001056 156.0
HKD2_k127_7795711_7 Pyoverdine/dityrosine biosynthesis protein - - - 0.000000000000000001533 101.0
HKD2_k127_7795711_8 membrane - - - 0.0000000002001 66.0
HKD2_k127_7795711_9 cellulose binding - - - 0.00000001478 63.0
HKD2_k127_781786_0 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 383.0
HKD2_k127_781786_1 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000935 231.0
HKD2_k127_781786_10 Histidine kinase - - - 0.0000000005713 68.0
HKD2_k127_781786_2 Inhibitor of apoptosis-promoting Bax1 - - - 0.000000000000000000000000000000000000000000000000000000000000003591 226.0
HKD2_k127_781786_3 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000002402 155.0
HKD2_k127_781786_4 Putative lumazine-binding - - - 0.0000000000000000000000000000000000001866 151.0
HKD2_k127_781786_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000000003566 134.0
HKD2_k127_781786_6 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000716 126.0
HKD2_k127_781786_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000002267 82.0
HKD2_k127_781786_8 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000001773 76.0
HKD2_k127_781786_9 lytic transglycosylase activity - - - 0.0000000004504 70.0
HKD2_k127_7839580_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.133e-218 705.0
HKD2_k127_7839580_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 8.943e-201 640.0
HKD2_k127_7839580_10 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 386.0
HKD2_k127_7839580_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 388.0
HKD2_k127_7839580_12 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
HKD2_k127_7839580_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
HKD2_k127_7839580_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 320.0
HKD2_k127_7839580_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008061 288.0
HKD2_k127_7839580_16 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003064 266.0
HKD2_k127_7839580_17 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000002414 252.0
HKD2_k127_7839580_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001259 243.0
HKD2_k127_7839580_19 NDK K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000001577 205.0
HKD2_k127_7839580_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 625.0
HKD2_k127_7839580_20 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.000000000000000000000000000000000000000000000000000000003861 219.0
HKD2_k127_7839580_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000003091 141.0
HKD2_k127_7839580_22 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000005085 114.0
HKD2_k127_7839580_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000001482 118.0
HKD2_k127_7839580_24 UPF0182 protein K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000198 98.0
HKD2_k127_7839580_3 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 618.0
HKD2_k127_7839580_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 589.0
HKD2_k127_7839580_5 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 573.0
HKD2_k127_7839580_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 506.0
HKD2_k127_7839580_7 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 499.0
HKD2_k127_7839580_8 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 505.0
HKD2_k127_7839580_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 433.0
HKD2_k127_7866901_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000004393 199.0
HKD2_k127_7866901_1 Bacterial regulatory protein, Fis family K07714 - - 0.00000000000000000187 87.0
HKD2_k127_7880576_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.426e-266 858.0
HKD2_k127_7880576_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 375.0
HKD2_k127_7880576_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000003004 157.0
HKD2_k127_7880576_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000001582 139.0
HKD2_k127_7885694_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 391.0
HKD2_k127_7885694_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 353.0
HKD2_k127_7887512_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 497.0
HKD2_k127_7887512_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002704 184.0
HKD2_k127_7907630_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18902 - - 0.0 1449.0
HKD2_k127_7907630_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 400.0
HKD2_k127_7907630_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 372.0
HKD2_k127_7907630_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002509 258.0
HKD2_k127_7907630_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000001912 97.0
HKD2_k127_7907630_5 SnoaL-like domain - - - 0.000000000000004873 87.0
HKD2_k127_7921158_0 Protein export membrane protein - - - 0.0 1444.0
HKD2_k127_7921158_1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000002008 236.0
HKD2_k127_7921158_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000004773 199.0
HKD2_k127_7921158_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000006195 97.0
HKD2_k127_7921158_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000003674 84.0
HKD2_k127_7921158_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000002262 67.0
HKD2_k127_7921158_6 - - - - 0.00008661 49.0
HKD2_k127_7933903_0 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 291.0
HKD2_k127_7933903_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 264.0
HKD2_k127_7933903_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000005869 231.0
HKD2_k127_7933903_3 Alpha/beta hydrolase family - - - 0.00000000000000000017 101.0
HKD2_k127_7933903_4 PDZ domain - - - 0.00000000000249 72.0
HKD2_k127_795227_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 2.905e-278 876.0
HKD2_k127_795227_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.108e-275 861.0
HKD2_k127_795227_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
HKD2_k127_795227_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 308.0
HKD2_k127_795227_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009493 253.0
HKD2_k127_795227_5 Ribonuclease B OB domain K03704 - - 0.0000000000000000000000000000002968 124.0
HKD2_k127_795227_6 Protein of unknown function (DUF721) - - - 0.00000000000005291 84.0
HKD2_k127_7974829_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 557.0
HKD2_k127_7974829_1 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000001663 211.0
HKD2_k127_8003027_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 403.0
HKD2_k127_8003027_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 387.0
HKD2_k127_8003027_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 314.0
HKD2_k127_8003027_3 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 269.0
HKD2_k127_8003027_4 Cell division protein FtsQ K03589 - - 0.0000000006382 71.0
HKD2_k127_8006570_0 DNA polymerase alpha chain like domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 501.0
HKD2_k127_8006570_1 PFAM peptidase M18 aminopeptidase I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
HKD2_k127_8006570_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 373.0
HKD2_k127_8006570_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 342.0
HKD2_k127_8006570_4 Peptidase, M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 302.0
HKD2_k127_8006570_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001246 286.0
HKD2_k127_8006570_6 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000002229 229.0
HKD2_k127_8006570_7 gluconolactonase activity - - - 0.000000000000000000000000000000000000000002154 175.0
HKD2_k127_8006570_8 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000002073 116.0
HKD2_k127_8020177_0 glucosamine-6-phosphate deaminase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 359.0
HKD2_k127_8020177_1 best DB hits BLAST gb AAC24510.1 K01174,K13529,K15051 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 3.1.31.1,3.2.2.21 0.000000000000000000000000000000000000282 150.0
HKD2_k127_8020177_2 glucosamine-6-phosphate deaminase activity - - - 0.00000000000005015 76.0
HKD2_k127_8055270_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.721e-251 803.0
HKD2_k127_8055270_1 - - - - 0.0000000000000000000000000000000000000000000000007827 189.0
HKD2_k127_8055270_2 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000003058 176.0
HKD2_k127_8055270_3 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000239 162.0
HKD2_k127_8055270_4 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000453 72.0
HKD2_k127_8059215_0 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 355.0
HKD2_k127_8059215_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007153 279.0
HKD2_k127_8059215_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 264.0
HKD2_k127_8059215_3 - - - - 0.00001125 51.0
HKD2_k127_8082351_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
HKD2_k127_8082351_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000002102 218.0
HKD2_k127_8082351_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000009808 134.0
HKD2_k127_8082351_3 Transcriptional regulator - - - 0.0000000000000000000000000000002348 141.0
HKD2_k127_8082351_4 PQQ-like domain K14028 - 1.1.2.7 0.000000000000003721 86.0
HKD2_k127_8091074_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 1.271e-311 977.0
HKD2_k127_8091074_1 E1-E2 ATPase K17686 - 3.6.3.54 3.592e-242 771.0
HKD2_k127_8091074_10 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 378.0
HKD2_k127_8091074_11 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 331.0
HKD2_k127_8091074_12 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 333.0
HKD2_k127_8091074_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 323.0
HKD2_k127_8091074_14 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
HKD2_k127_8091074_15 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 304.0
HKD2_k127_8091074_16 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 308.0
HKD2_k127_8091074_17 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000001576 267.0
HKD2_k127_8091074_18 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003163 262.0
HKD2_k127_8091074_19 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004103 273.0
HKD2_k127_8091074_2 abc transporter atp-binding protein K06147 - - 6.004e-215 694.0
HKD2_k127_8091074_20 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000004736 253.0
HKD2_k127_8091074_21 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000002243 246.0
HKD2_k127_8091074_22 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005077 248.0
HKD2_k127_8091074_23 nitrous oxide K19341 - - 0.00000000000000000000000000000000000000000000000000000000000006996 233.0
HKD2_k127_8091074_24 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000001655 210.0
HKD2_k127_8091074_25 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000004585 223.0
HKD2_k127_8091074_26 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000006457 184.0
HKD2_k127_8091074_27 oxidoreductase activity K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000367 176.0
HKD2_k127_8091074_28 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000000009183 160.0
HKD2_k127_8091074_29 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000004528 158.0
HKD2_k127_8091074_3 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 544.0
HKD2_k127_8091074_30 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000004695 156.0
HKD2_k127_8091074_31 Acetyltransferase (GNAT) domain K22441 - 2.3.1.57 0.000000000000000000000000000000000005433 150.0
HKD2_k127_8091074_32 Cytochrome c - - - 0.0000000000000000000000000000000003521 137.0
HKD2_k127_8091074_33 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000004513 145.0
HKD2_k127_8091074_34 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000009126 133.0
HKD2_k127_8091074_35 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000001825 135.0
HKD2_k127_8091074_36 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000009449 134.0
HKD2_k127_8091074_37 2 iron, 2 sulfur cluster binding K13643 - - 0.0000000000000000000000000002395 118.0
HKD2_k127_8091074_38 - - - - 0.000000000000000000000000006053 113.0
HKD2_k127_8091074_39 Peptidase family M23 - - - 0.0000000000000000000001728 112.0
HKD2_k127_8091074_4 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 507.0
HKD2_k127_8091074_40 Glyoxalase-like domain - - - 0.00000000000000000000361 106.0
HKD2_k127_8091074_41 NosL K19342 - - 0.00000000000000001536 98.0
HKD2_k127_8091074_43 Heavy-metal-associated domain K07213 - - 0.0000000000003052 73.0
HKD2_k127_8091074_44 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000002805 78.0
HKD2_k127_8091074_45 signal transduction histidine kinase - - - 0.00000001444 67.0
HKD2_k127_8091074_5 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 487.0
HKD2_k127_8091074_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 482.0
HKD2_k127_8091074_7 phosphorelay signal transduction system K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 409.0
HKD2_k127_8091074_8 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 380.0
HKD2_k127_8091074_9 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 392.0
HKD2_k127_8155214_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 1.074e-199 634.0
HKD2_k127_8155214_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 428.0
HKD2_k127_8155214_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 383.0
HKD2_k127_8155214_3 Nitrate reductase cytochrome c-type subunit (NapB) K02568 - - 0.000000000000000000000000001234 130.0
HKD2_k127_8155214_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000001689 113.0
HKD2_k127_8169038_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 594.0
HKD2_k127_8169038_1 L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000001312 165.0
HKD2_k127_8172558_0 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 599.0
HKD2_k127_8172558_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 521.0
HKD2_k127_8172558_2 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006426 280.0
HKD2_k127_8172558_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
HKD2_k127_8172558_4 Protein of unknown function (DUF3568) - - - 0.00000000000003315 80.0
HKD2_k127_8196902_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 567.0
HKD2_k127_8196902_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 447.0
HKD2_k127_8196902_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 391.0
HKD2_k127_8196902_3 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000001481 211.0
HKD2_k127_8196902_4 Amidohydrolase family - - - 0.000000000000000000000001551 112.0
HKD2_k127_8196902_5 4Fe-4S ferredoxin - - - 0.00000000004211 70.0
HKD2_k127_8220815_0 - - - - 0.00000000000000000000000000000000003006 154.0
HKD2_k127_8220815_2 BON domain - - - 0.00000001339 65.0
HKD2_k127_8220815_3 Tetratricopeptide repeat - - - 0.000005405 57.0
HKD2_k127_8220815_4 Septum formation initiator K05589 - - 0.00003359 47.0
HKD2_k127_8243622_0 Involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000001597 189.0
HKD2_k127_8243622_1 periplasmic or secreted lipoprotein - - - 0.00000000000000001968 84.0
HKD2_k127_8243622_2 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000005088 79.0
HKD2_k127_8243622_3 Type IV secretory pathway VirD4 - - - 0.0000000002324 72.0
HKD2_k127_8243622_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000003873 55.0
HKD2_k127_8243622_5 Type IV secretory system Conjugative DNA transfer - - - 0.000006588 59.0
HKD2_k127_8243622_6 TraM recognition site of TraD and TraG - - - 0.0008956 50.0
HKD2_k127_8279021_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 453.0
HKD2_k127_8279021_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000001924 170.0
HKD2_k127_8279021_2 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000004074 169.0
HKD2_k127_8279021_3 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000008231 156.0
HKD2_k127_8279021_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000001012 119.0
HKD2_k127_8279021_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000001041 107.0
HKD2_k127_8279021_6 - - - - 0.00000000000000002973 94.0
HKD2_k127_8298021_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.859e-229 759.0
HKD2_k127_8298021_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 9.665e-213 701.0
HKD2_k127_8298021_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000001316 81.0
HKD2_k127_8298021_11 Large extracellular alpha-helical protein K13735 - - 0.000000000001696 81.0
HKD2_k127_8298021_12 Outer membrane protein beta-barrel domain - - - 0.00000000004759 74.0
HKD2_k127_8298021_13 outer membrane efflux protein - - - 0.000001637 60.0
HKD2_k127_8298021_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 597.0
HKD2_k127_8298021_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 330.0
HKD2_k127_8298021_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001366 289.0
HKD2_k127_8298021_5 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000001415 247.0
HKD2_k127_8298021_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 246.0
HKD2_k127_8298021_7 OsmC-like protein K07397 - - 0.00000000000000000000000000000000008496 143.0
HKD2_k127_8298021_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000003164 136.0
HKD2_k127_8298021_9 Mechanosensitive ion channel - - - 0.000000000000000000000276 106.0
HKD2_k127_8381951_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.688e-196 622.0
HKD2_k127_8381951_1 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 509.0
HKD2_k127_8381951_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 407.0
HKD2_k127_8381951_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 337.0
HKD2_k127_8381951_4 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000007495 203.0
HKD2_k127_8381951_5 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000004826 140.0
HKD2_k127_8381951_6 - - - - 0.00000000000000000000000000007787 126.0
HKD2_k127_8381951_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000003261 115.0
HKD2_k127_8381951_8 COG0457 FOG TPR repeat - - - 0.000000006452 66.0
HKD2_k127_8381951_9 C-terminal domain of histone - - - 0.00000001782 66.0
HKD2_k127_8390360_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000005787 73.0
HKD2_k127_8390360_1 Forkhead associated domain - - - 0.0001334 52.0
HKD2_k127_8434674_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 587.0
HKD2_k127_8434674_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 393.0
HKD2_k127_8434674_2 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000000000000000000000000000000000004202 171.0
HKD2_k127_8434674_3 Zinc finger domain - - - 0.00000000000000000009982 100.0
HKD2_k127_8434674_4 Binds directly to 16S ribosomal RNA K02968 - - 0.00001148 48.0
HKD2_k127_8501479_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 489.0
HKD2_k127_8501479_1 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007805 280.0
HKD2_k127_8501479_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000002549 105.0
HKD2_k127_8503540_0 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 330.0
HKD2_k127_8503540_1 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000007393 181.0
HKD2_k127_8503540_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000002159 120.0
HKD2_k127_8509531_0 TonB dependent receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 389.0
HKD2_k127_8509531_1 Major facilitator Superfamily K03762 - - 0.0000000000000000000000000000000000000000000009337 187.0
HKD2_k127_8526948_0 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 4.128e-195 628.0
HKD2_k127_8526948_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 382.0
HKD2_k127_8526948_2 TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein - - - 0.00000000000000000000000000000000000000000000000008259 190.0
HKD2_k127_8526948_3 HD domain - - - 0.0000000000000000000000000000000002573 138.0
HKD2_k127_8526948_4 - - - - 0.0000000000000000000000000000000004485 146.0
HKD2_k127_8526948_5 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000003271 100.0
HKD2_k127_8548365_0 ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004167 282.0
HKD2_k127_8548365_1 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003316 258.0
HKD2_k127_857859_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 5.244e-250 800.0
HKD2_k127_857859_1 Carboxyl transferase domain - - - 2.21e-242 769.0
HKD2_k127_857859_10 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001697 205.0
HKD2_k127_857859_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000002064 193.0
HKD2_k127_857859_12 enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000002193 193.0
HKD2_k127_857859_13 - - - - 0.000000000000000000000000000000000000002364 149.0
HKD2_k127_857859_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000174 142.0
HKD2_k127_857859_15 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000001697 152.0
HKD2_k127_857859_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000002958 131.0
HKD2_k127_857859_17 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000561 110.0
HKD2_k127_857859_18 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000552 106.0
HKD2_k127_857859_19 Outer membrane protein beta-barrel domain - - - 0.000000000000007514 82.0
HKD2_k127_857859_2 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 649.0
HKD2_k127_857859_20 - - - - 0.0000001217 57.0
HKD2_k127_857859_3 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 597.0
HKD2_k127_857859_4 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 394.0
HKD2_k127_857859_5 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 381.0
HKD2_k127_857859_6 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 320.0
HKD2_k127_857859_7 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008457 299.0
HKD2_k127_857859_8 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000008171 265.0
HKD2_k127_857859_9 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000001092 226.0
HKD2_k127_859064_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1306.0
HKD2_k127_859064_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 441.0
HKD2_k127_859064_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 316.0
HKD2_k127_8716253_0 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 295.0
HKD2_k127_8716253_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000002548 128.0
HKD2_k127_8733037_0 B3/4 domain K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 616.0
HKD2_k127_8733037_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 347.0
HKD2_k127_8733037_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000003717 146.0
HKD2_k127_8733037_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000007144 116.0
HKD2_k127_8733037_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002041 78.0
HKD2_k127_8733037_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000002341 76.0
HKD2_k127_8812722_0 amino acid K03294 - - 1.23e-200 633.0
HKD2_k127_8812722_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 562.0
HKD2_k127_8812722_10 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000003873 157.0
HKD2_k127_8812722_11 membrane K11622 - - 0.0000000000000000000000000000000000000009423 166.0
HKD2_k127_8812722_12 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000003775 132.0
HKD2_k127_8812722_13 PFAM NifU-like domain - - - 0.00000000000004952 75.0
HKD2_k127_8812722_14 - - - - 0.00000001373 64.0
HKD2_k127_8812722_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 402.0
HKD2_k127_8812722_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
HKD2_k127_8812722_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 312.0
HKD2_k127_8812722_5 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005217 269.0
HKD2_k127_8812722_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000009402 258.0
HKD2_k127_8812722_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000002988 254.0
HKD2_k127_8812722_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
HKD2_k127_8812722_9 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000001479 188.0
HKD2_k127_8949301_0 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 473.0
HKD2_k127_8949301_1 sulfate ABC transporter, permease protein CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 403.0
HKD2_k127_8949301_2 sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 388.0
HKD2_k127_8949301_3 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000003391 160.0
HKD2_k127_8949301_4 - - - - 0.000000000000000000000000000000000000337 144.0
HKD2_k127_8949301_5 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000000000000000001879 132.0
HKD2_k127_8962439_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.424e-231 718.0
HKD2_k127_8962439_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 405.0
HKD2_k127_8962439_2 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007986 256.0
HKD2_k127_8962439_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
HKD2_k127_8962439_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000006877 178.0
HKD2_k127_8962439_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000008884 109.0
HKD2_k127_8962439_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000007408 104.0
HKD2_k127_9031858_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 325.0
HKD2_k127_9031858_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
HKD2_k127_9049031_0 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 328.0
HKD2_k127_9049031_1 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001226 294.0
HKD2_k127_9049031_10 Polysaccharide deacetylase - - - 0.000000009164 60.0
HKD2_k127_9049031_11 SMART phosphoesterase PHP domain protein - - - 0.000008878 56.0
HKD2_k127_9049031_2 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003204 282.0
HKD2_k127_9049031_3 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000001866 229.0
HKD2_k127_9049031_4 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000000000000000000000000000000000000000001038 220.0
HKD2_k127_9049031_5 VanZ like family - - - 0.00000000000000000000000000000000000000000002704 184.0
HKD2_k127_9049031_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000005851 141.0
HKD2_k127_9049031_7 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000000000000000008786 142.0
HKD2_k127_9049031_8 extracellular repeat, HAF family - - - 0.0000000003063 73.0
HKD2_k127_9049031_9 Methyltransferase domain - - - 0.000000008682 65.0
HKD2_k127_9078488_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 314.0
HKD2_k127_9078488_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000618 282.0
HKD2_k127_9078488_10 Histidine kinase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000004963 177.0
HKD2_k127_9078488_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000000000000000000000000000000552 165.0
HKD2_k127_9078488_12 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000003288 160.0
HKD2_k127_9078488_13 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000793 140.0
HKD2_k127_9078488_14 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000001296 133.0
HKD2_k127_9078488_15 Protein of unknown function (DUF983) - - - 0.000000000000000000000005245 109.0
HKD2_k127_9078488_16 OmpA family - - - 0.00000000001561 74.0
HKD2_k127_9078488_17 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000005713 68.0
HKD2_k127_9078488_2 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001999 271.0
HKD2_k127_9078488_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009377 262.0
HKD2_k127_9078488_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000001043 259.0
HKD2_k127_9078488_5 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001311 249.0
HKD2_k127_9078488_6 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000009512 231.0
HKD2_k127_9078488_7 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000001004 234.0
HKD2_k127_9078488_8 antisigma factor binding K04749,K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001109 223.0
HKD2_k127_9078488_9 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000002577 165.0
HKD2_k127_9097478_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 494.0
HKD2_k127_9097478_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 449.0
HKD2_k127_9097478_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 446.0
HKD2_k127_9097478_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 322.0
HKD2_k127_9097478_4 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002646 271.0
HKD2_k127_9097478_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000008197 85.0
HKD2_k127_9100552_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1495.0
HKD2_k127_9100552_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 4.711e-284 887.0
HKD2_k127_9100552_10 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 585.0
HKD2_k127_9100552_11 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 556.0
HKD2_k127_9100552_12 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 538.0
HKD2_k127_9100552_13 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 526.0
HKD2_k127_9100552_14 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 450.0
HKD2_k127_9100552_15 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 450.0
HKD2_k127_9100552_16 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 381.0
HKD2_k127_9100552_17 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 332.0
HKD2_k127_9100552_18 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 337.0
HKD2_k127_9100552_19 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 349.0
HKD2_k127_9100552_2 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.006e-279 872.0
HKD2_k127_9100552_20 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 311.0
HKD2_k127_9100552_21 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000162 272.0
HKD2_k127_9100552_22 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000006446 263.0
HKD2_k127_9100552_23 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001469 218.0
HKD2_k127_9100552_24 arginine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000003592 203.0
HKD2_k127_9100552_25 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000000000001624 196.0
HKD2_k127_9100552_26 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000002352 196.0
HKD2_k127_9100552_27 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000009762 175.0
HKD2_k127_9100552_28 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000002708 153.0
HKD2_k127_9100552_29 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000003769 134.0
HKD2_k127_9100552_3 4Fe-4S dicluster domain K00184 - - 3.798e-237 767.0
HKD2_k127_9100552_30 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000158 138.0
HKD2_k127_9100552_31 PFAM Bacterial regulatory proteins, tetR family K09017,K22295 - - 0.000000000000000000000000000000005698 136.0
HKD2_k127_9100552_32 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000001703 132.0
HKD2_k127_9100552_33 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000006218 110.0
HKD2_k127_9100552_34 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000001009 108.0
HKD2_k127_9100552_36 - - - - 0.0004985 49.0
HKD2_k127_9100552_37 membrane-associated Zn-dependent proteases 1 K11749 GO:0008150,GO:0040007 - 0.0009135 49.0
HKD2_k127_9100552_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.593e-221 701.0
HKD2_k127_9100552_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.892e-217 690.0
HKD2_k127_9100552_6 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 2.308e-216 683.0
HKD2_k127_9100552_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.289e-197 625.0
HKD2_k127_9100552_8 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 613.0
HKD2_k127_9100552_9 M3B, thimet oligopeptidase F K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 640.0
HKD2_k127_914832_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 3.911e-270 841.0
HKD2_k127_914832_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 5.168e-255 797.0
HKD2_k127_914832_10 sulfurtransferase K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 330.0
HKD2_k127_914832_11 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 331.0
HKD2_k127_914832_12 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 288.0
HKD2_k127_914832_13 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008846 286.0
HKD2_k127_914832_14 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000459 271.0
HKD2_k127_914832_15 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000006953 235.0
HKD2_k127_914832_16 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000341 205.0
HKD2_k127_914832_17 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000006722 191.0
HKD2_k127_914832_18 Thioredoxin - - - 0.0000000000000000000000000000000000000000000003027 174.0
HKD2_k127_914832_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000005275 127.0
HKD2_k127_914832_2 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.166e-216 690.0
HKD2_k127_914832_20 - - - - 0.00000000000001448 84.0
HKD2_k127_914832_21 transcriptional regulator - - - 0.00000000000002519 81.0
HKD2_k127_914832_22 Universal stress protein family K07090 - - 0.0000000002908 70.0
HKD2_k127_914832_23 Surface antigen - - - 0.0000000006307 72.0
HKD2_k127_914832_24 Protein of unknown function (DUF2892) - - - 0.000000002726 63.0
HKD2_k127_914832_25 WD40-like Beta Propeller Repeat - - - 0.00008441 56.0
HKD2_k127_914832_3 DinB superfamily K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 490.0
HKD2_k127_914832_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 428.0
HKD2_k127_914832_5 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 441.0
HKD2_k127_914832_6 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 424.0
HKD2_k127_914832_7 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 428.0
HKD2_k127_914832_8 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 410.0
HKD2_k127_914832_9 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 339.0
HKD2_k127_9148951_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.788e-319 988.0
HKD2_k127_9148951_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.265e-289 906.0
HKD2_k127_9148951_2 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001249 249.0
HKD2_k127_9148951_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000007492 228.0
HKD2_k127_9148951_4 EVE domain - - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD2_k127_9148951_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.0000000000000000000000003764 123.0
HKD2_k127_9148951_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000004132 112.0
HKD2_k127_9148951_7 Glycoprotease family K14742 - - 0.000000000000000000001399 108.0
HKD2_k127_9173635_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1202.0
HKD2_k127_9173635_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 280.0
HKD2_k127_9173635_2 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000143 166.0
HKD2_k127_9187734_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 363.0
HKD2_k127_9187734_1 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000218 259.0
HKD2_k127_9187734_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000009055 207.0
HKD2_k127_9187734_3 OsmC-like protein - - - 0.00000000000000001106 83.0
HKD2_k127_9203588_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1176.0
HKD2_k127_9203588_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 5.626e-216 677.0
HKD2_k127_9203588_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000008026 206.0
HKD2_k127_9203588_11 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000002583 175.0
HKD2_k127_9203588_12 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000001551 109.0
HKD2_k127_9203588_13 - - - - 0.000000000000000000007593 96.0
HKD2_k127_9203588_14 - - - - 0.0000000000000002148 88.0
HKD2_k127_9203588_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000008522 78.0
HKD2_k127_9203588_2 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 554.0
HKD2_k127_9203588_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 516.0
HKD2_k127_9203588_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 430.0
HKD2_k127_9203588_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 299.0
HKD2_k127_9203588_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000001223 244.0
HKD2_k127_9203588_7 Carboxypeptidase regulatory-like domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000351 246.0
HKD2_k127_9203588_8 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000005757 246.0
HKD2_k127_9203588_9 - - - - 0.0000000000000000000000000000000000000000000000000000000007653 210.0
HKD2_k127_9226363_0 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000002072 154.0
HKD2_k127_9226363_1 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000000000000000001016 146.0
HKD2_k127_9226363_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000002376 134.0
HKD2_k127_9236475_0 ABC transporter transmembrane region K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 584.0
HKD2_k127_9236475_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 491.0
HKD2_k127_9236475_10 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000001674 163.0
HKD2_k127_9236475_11 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000005771 140.0
HKD2_k127_9236475_12 - - - - 0.000000003901 67.0
HKD2_k127_9236475_2 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 370.0
HKD2_k127_9236475_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 341.0
HKD2_k127_9236475_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 345.0
HKD2_k127_9236475_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 334.0
HKD2_k127_9236475_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 305.0
HKD2_k127_9236475_7 PFAM Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 308.0
HKD2_k127_9236475_8 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005289 286.0
HKD2_k127_9236475_9 Glycosyl hydrolase family 3 N terminal domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000101 273.0
HKD2_k127_9243_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 1.749e-242 779.0
HKD2_k127_9243_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 564.0
HKD2_k127_9243_2 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 438.0
HKD2_k127_9243_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
HKD2_k127_9243_4 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001173 254.0
HKD2_k127_9243_5 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003343 246.0
HKD2_k127_9243_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000005296 242.0
HKD2_k127_9243_7 domain, Protein K01179,K07260,K13735 - 3.2.1.4,3.4.17.14 0.000000000000000000000000000000000000000000000000000000000005116 229.0
HKD2_k127_9243_8 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000007755 218.0
HKD2_k127_9294375_0 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 357.0
HKD2_k127_9294375_1 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001005 218.0
HKD2_k127_9294375_2 Histidine kinase - - - 0.000000000000000000000000000000000001215 153.0
HKD2_k127_9294375_4 - - - - 0.00000001015 64.0
HKD2_k127_9331994_0 Atp-dependent helicase - - - 5.984e-307 964.0
HKD2_k127_9331994_1 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 505.0
HKD2_k127_9331994_2 chemotaxis protein K03406 - - 0.000000000000000000001928 110.0
HKD2_k127_9331994_3 - - - - 0.00000000000000001805 96.0
HKD2_k127_9331994_4 PAS modulated sigma54 specific transcriptional regulator, Fis family - - - 0.0000263 52.0
HKD2_k127_9375504_0 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000004422 194.0
HKD2_k127_9375504_1 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000001614 189.0
HKD2_k127_9378228_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 2.096e-260 836.0
HKD2_k127_9378228_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 586.0
HKD2_k127_9378228_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
HKD2_k127_9378228_3 Allophanate hydrolase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000002139 207.0
HKD2_k127_9378228_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000006798 197.0
HKD2_k127_9378228_5 allophanate hydrolase subunit 2 K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000005282 207.0
HKD2_k127_9378228_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000009659 120.0
HKD2_k127_9378228_7 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000001402 108.0
HKD2_k127_9386659_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 470.0
HKD2_k127_9386659_1 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 445.0
HKD2_k127_9386659_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 429.0
HKD2_k127_9386659_3 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000003903 174.0
HKD2_k127_9386659_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000001221 168.0
HKD2_k127_9386659_5 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000005874 137.0
HKD2_k127_9386659_6 ThiS family K03636 - - 0.00000000004249 72.0
HKD2_k127_9430177_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000007135 205.0
HKD2_k127_9430177_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000006018 102.0
HKD2_k127_9430177_2 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000002116 59.0
HKD2_k127_9448957_0 glutamine synthetase K01915 - 6.3.1.2 1.846e-267 846.0
HKD2_k127_9448957_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 427.0
HKD2_k127_9448957_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 306.0
HKD2_k127_9448957_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000006824 171.0
HKD2_k127_9448957_4 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000002331 115.0
HKD2_k127_9448957_5 BON domain - - - 0.0000008588 53.0
HKD2_k127_9515520_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 572.0
HKD2_k127_9515520_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 472.0
HKD2_k127_9515520_2 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 344.0
HKD2_k127_9515520_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
HKD2_k127_9515520_4 heme binding - - - 0.00000000000000000000000000000000000000000000000000000000000002811 239.0
HKD2_k127_9515520_5 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000004285 228.0
HKD2_k127_9515520_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000001334 136.0
HKD2_k127_9515520_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000009092 123.0
HKD2_k127_9597396_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 518.0
HKD2_k127_9597396_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
HKD2_k127_9597396_2 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 395.0
HKD2_k127_9597396_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 391.0
HKD2_k127_9597396_4 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000001624 190.0
HKD2_k127_9597396_5 Transporter associated domain - - - 0.0000000000000000000000000000000000000112 167.0
HKD2_k127_9597396_6 Histidine kinase - - - 0.0000000000000000000000000003946 132.0
HKD2_k127_9597396_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000003724 116.0
HKD2_k127_9597396_8 Helix-hairpin-helix motif - - - 0.00000000000000000001086 95.0
HKD2_k127_9597396_9 lysyltransferase activity K07027,K20468 - - 0.0000006759 60.0
HKD2_k127_9629859_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
HKD2_k127_9629859_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 296.0
HKD2_k127_9629859_2 COG1309 Transcriptional regulator K02167 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00002441 53.0
HKD2_k127_9697021_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.515e-202 645.0
HKD2_k127_9697021_1 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 475.0
HKD2_k127_9697021_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 434.0
HKD2_k127_9697021_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008503 286.0
HKD2_k127_9697021_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005276 246.0
HKD2_k127_9697021_5 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000003379 196.0
HKD2_k127_9697021_6 Histidine kinase - - - 0.00000000004438 72.0
HKD2_k127_9730181_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
HKD2_k127_9730181_1 alpha beta K07100 - - 0.0000000000000000000000004835 113.0
HKD2_k127_9730181_2 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000317 81.0
HKD2_k127_9730181_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0003245 43.0
HKD2_k127_9731278_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1169.0
HKD2_k127_9731278_1 lysine biosynthetic process via aminoadipic acid - - - 1.241e-236 760.0
HKD2_k127_9731278_10 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000006614 231.0
HKD2_k127_9731278_11 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000002965 211.0
HKD2_k127_9731278_12 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000002041 180.0
HKD2_k127_9731278_13 CS domain K13993 - - 0.00000000000000000000000000002085 124.0
HKD2_k127_9731278_15 Rhodanese Homology Domain K03972 - - 0.0000000000000007812 83.0
HKD2_k127_9731278_16 - - - - 0.0000145 59.0
HKD2_k127_9731278_2 Histidine kinase - - - 2.668e-214 681.0
HKD2_k127_9731278_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 483.0
HKD2_k127_9731278_4 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 441.0
HKD2_k127_9731278_5 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003383 296.0
HKD2_k127_9731278_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003655 261.0
HKD2_k127_9731278_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008285 246.0
HKD2_k127_9731278_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000003405 250.0
HKD2_k127_9731278_9 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000009011 229.0
HKD2_k127_9764716_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 580.0
HKD2_k127_9764716_1 Type I phosphodiesterase / nucleotide pyrophosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 469.0
HKD2_k127_9764716_2 LytB protein K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 443.0
HKD2_k127_9764716_3 decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 427.0
HKD2_k127_9764716_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 326.0
HKD2_k127_9764716_5 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 300.0
HKD2_k127_9764716_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 297.0
HKD2_k127_9764716_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00001491 56.0
HKD2_k127_9764716_8 Cytochrome C oxidase, cbb3-type, subunit III K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00005395 55.0
HKD2_k127_9764716_9 - - - - 0.0002483 50.0
HKD2_k127_9767352_0 MMPL family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 319.0
HKD2_k127_9767352_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 319.0
HKD2_k127_9767352_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001318 291.0
HKD2_k127_9767352_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000002341 203.0
HKD2_k127_9938585_0 Aminotransferase class-III K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 415.0
HKD2_k127_9938585_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 381.0
HKD2_k127_9938585_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 301.0
HKD2_k127_9938585_4 - - - - 0.00001097 57.0
HKD2_k127_9938585_5 - - - - 0.0001412 49.0
HKD2_k127_995513_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 478.0
HKD2_k127_995513_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 453.0
HKD2_k127_995513_10 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000004952 88.0
HKD2_k127_995513_11 PAS fold - - - 0.0000000000001964 74.0
HKD2_k127_995513_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
HKD2_k127_995513_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 305.0
HKD2_k127_995513_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001757 255.0
HKD2_k127_995513_5 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000002792 252.0
HKD2_k127_995513_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000000000000000000001205 184.0
HKD2_k127_995513_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000004642 159.0
HKD2_k127_995513_8 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000007564 169.0
HKD2_k127_995513_9 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000003792 160.0
HKD2_k127_9972397_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 362.0
HKD2_k127_9972397_1 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 349.0
HKD2_k127_9972397_2 AcrB/AcrD/AcrF family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 326.0