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Overview

ID MAG01828
Name HKD2_bin.90
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order IMCC26256
Family JAENVU01
Genus
Species
Assembly information
Completeness (%) 96.18
Contamination (%) 1.23
GC content (%) 72.0
N50 (bp) 61,219
Genome size (bp) 3,732,312

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3337

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10004601_0 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 320.0
HKD2_k127_10004601_1 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000001947 237.0
HKD2_k127_10004601_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000003996 233.0
HKD2_k127_10004601_3 Prokaryotic N-terminal methylation motif - - - 0.00000000000001914 85.0
HKD2_k127_10004601_4 general secretion pathway protein K02456,K02650 - - 0.00000003278 62.0
HKD2_k127_1098938_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1089.0
HKD2_k127_1098938_1 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 638.0
HKD2_k127_1098938_10 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007029 256.0
HKD2_k127_1098938_11 oligosaccharyl transferase activity K19003,K20327 - 2.4.1.336 0.00000000000000000000000000000000000000000000000000000000000000000001937 254.0
HKD2_k127_1098938_12 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001637 236.0
HKD2_k127_1098938_13 Domain of unknown function (DUF1996) - - - 0.0000000000000000000000000000000000001297 154.0
HKD2_k127_1098938_14 Sigma-70 region 2 - - - 0.0000000000000000000000000000000002093 143.0
HKD2_k127_1098938_15 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000003209 151.0
HKD2_k127_1098938_16 Protein of unknown function (DUF1349) K01183 - 3.2.1.14 0.000000000000000000000000000000000866 153.0
HKD2_k127_1098938_17 Parallel beta-helix repeats - - - 0.0000000000000000000000000000001172 145.0
HKD2_k127_1098938_18 PQQ enzyme repeat K05889 - 1.1.2.6 0.000000000000000000003495 111.0
HKD2_k127_1098938_19 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000002537 86.0
HKD2_k127_1098938_2 FAD linked oxidases, C-terminal domain K00104 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 590.0
HKD2_k127_1098938_20 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000008182 74.0
HKD2_k127_1098938_21 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.00000000008593 77.0
HKD2_k127_1098938_22 Fibronectin type III domain - - - 0.0000000002886 75.0
HKD2_k127_1098938_23 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000308 73.0
HKD2_k127_1098938_24 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.000000132 67.0
HKD2_k127_1098938_25 Pectinesterase K01051 - 3.1.1.11 0.000006137 62.0
HKD2_k127_1098938_26 Trypsin-like serine protease - - - 0.00001185 57.0
HKD2_k127_1098938_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 586.0
HKD2_k127_1098938_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 491.0
HKD2_k127_1098938_5 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 447.0
HKD2_k127_1098938_6 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 444.0
HKD2_k127_1098938_7 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 389.0
HKD2_k127_1098938_8 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008181 306.0
HKD2_k127_1098938_9 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001176 287.0
HKD2_k127_122755_0 acyl-CoA dehydrogenase - - - 4.248e-218 686.0
HKD2_k127_122755_1 Carboxyl transferase domain - - - 1.336e-216 694.0
HKD2_k127_122755_10 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
HKD2_k127_122755_11 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 359.0
HKD2_k127_122755_12 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 356.0
HKD2_k127_122755_13 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 354.0
HKD2_k127_122755_14 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 333.0
HKD2_k127_122755_15 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 343.0
HKD2_k127_122755_16 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 336.0
HKD2_k127_122755_17 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 335.0
HKD2_k127_122755_18 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 321.0
HKD2_k127_122755_19 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001059 273.0
HKD2_k127_122755_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K14733 - 1.14.13.107 1.36e-206 651.0
HKD2_k127_122755_20 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001367 238.0
HKD2_k127_122755_21 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000001566 203.0
HKD2_k127_122755_22 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000008865 206.0
HKD2_k127_122755_23 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
HKD2_k127_122755_24 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000001415 194.0
HKD2_k127_122755_25 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000003906 182.0
HKD2_k127_122755_26 FR47-like protein K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000004961 173.0
HKD2_k127_122755_27 Oxidoreductase FAD-binding domain K00529,K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.18.1.3 0.00000000000000000000000000000000000000004152 165.0
HKD2_k127_122755_28 Recombinase - - - 0.0000000000000000000000000002164 117.0
HKD2_k127_122755_29 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000004625 123.0
HKD2_k127_122755_3 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 523.0
HKD2_k127_122755_30 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000001298 83.0
HKD2_k127_122755_31 Protein of unknown function (DUF2800) K07465 - - 0.000001375 61.0
HKD2_k127_122755_32 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.00006355 52.0
HKD2_k127_122755_4 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 494.0
HKD2_k127_122755_5 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 450.0
HKD2_k127_122755_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 425.0
HKD2_k127_122755_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 393.0
HKD2_k127_122755_8 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 393.0
HKD2_k127_122755_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 360.0
HKD2_k127_1376070_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.896e-235 739.0
HKD2_k127_1376070_1 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
HKD2_k127_1376070_10 - K07224 - - 0.0000000000000000000000000000000000000000000000008548 185.0
HKD2_k127_1376070_11 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000001557 141.0
HKD2_k127_1376070_12 AMP binding - - - 0.000000000000000000000000000001996 126.0
HKD2_k127_1376070_13 ThiS family K03636 - - 0.00000000000000000000000003626 123.0
HKD2_k127_1376070_14 Cell envelope-related transcriptional attenuator domain - - - 0.0000001411 62.0
HKD2_k127_1376070_2 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 458.0
HKD2_k127_1376070_3 synthase K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 370.0
HKD2_k127_1376070_4 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 348.0
HKD2_k127_1376070_5 Glycosyl transferase family 2 K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 308.0
HKD2_k127_1376070_6 Glycerate kinase family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008016 294.0
HKD2_k127_1376070_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000006213 258.0
HKD2_k127_1376070_8 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000001547 192.0
HKD2_k127_1376070_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000005687 194.0
HKD2_k127_1572657_0 MMPL family K07003 - - 3.223e-257 821.0
HKD2_k127_1572657_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 580.0
HKD2_k127_1572657_2 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 439.0
HKD2_k127_1572657_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 353.0
HKD2_k127_1572657_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
HKD2_k127_1572657_5 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 306.0
HKD2_k127_1572657_6 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000006434 127.0
HKD2_k127_1572657_7 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.0000000000000002477 81.0
HKD2_k127_1572657_8 - - - - 0.000007789 49.0
HKD2_k127_1685740_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1421.0
HKD2_k127_1685740_1 Pfam Sulfatase K01130 - 3.1.6.1 1.596e-299 937.0
HKD2_k127_1685740_10 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 434.0
HKD2_k127_1685740_11 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 436.0
HKD2_k127_1685740_12 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 421.0
HKD2_k127_1685740_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 417.0
HKD2_k127_1685740_14 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
HKD2_k127_1685740_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 409.0
HKD2_k127_1685740_16 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 370.0
HKD2_k127_1685740_17 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 387.0
HKD2_k127_1685740_18 Sulfotransferase domain K01014 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 361.0
HKD2_k127_1685740_19 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 354.0
HKD2_k127_1685740_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 591.0
HKD2_k127_1685740_20 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 354.0
HKD2_k127_1685740_21 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
HKD2_k127_1685740_22 Creatinase/Prolidase N-terminal domain K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 323.0
HKD2_k127_1685740_23 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 331.0
HKD2_k127_1685740_24 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 329.0
HKD2_k127_1685740_25 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 312.0
HKD2_k127_1685740_26 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 295.0
HKD2_k127_1685740_27 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001848 305.0
HKD2_k127_1685740_28 3-dehydroquinate synthase K16020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001126 269.0
HKD2_k127_1685740_29 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000001767 268.0
HKD2_k127_1685740_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 578.0
HKD2_k127_1685740_30 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001611 259.0
HKD2_k127_1685740_31 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 266.0
HKD2_k127_1685740_32 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000004024 254.0
HKD2_k127_1685740_33 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000006979 235.0
HKD2_k127_1685740_34 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000008232 228.0
HKD2_k127_1685740_35 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000005332 226.0
HKD2_k127_1685740_36 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000003717 229.0
HKD2_k127_1685740_37 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
HKD2_k127_1685740_38 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000002967 224.0
HKD2_k127_1685740_39 Pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000001982 211.0
HKD2_k127_1685740_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 556.0
HKD2_k127_1685740_40 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000003932 206.0
HKD2_k127_1685740_41 Membrane - - - 0.00000000000000000000000000000000000000000000000000003168 211.0
HKD2_k127_1685740_42 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000005637 196.0
HKD2_k127_1685740_43 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000003658 194.0
HKD2_k127_1685740_44 domain protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000005315 188.0
HKD2_k127_1685740_45 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000001043 188.0
HKD2_k127_1685740_46 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000359 180.0
HKD2_k127_1685740_47 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.00000000000000000000000000000000000000000000001512 176.0
HKD2_k127_1685740_48 Arginine repressor, DNA binding domain K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000002136 181.0
HKD2_k127_1685740_49 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000009152 167.0
HKD2_k127_1685740_5 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 561.0
HKD2_k127_1685740_50 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000000000001814 162.0
HKD2_k127_1685740_51 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000001829 164.0
HKD2_k127_1685740_52 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000002183 162.0
HKD2_k127_1685740_53 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000006315 163.0
HKD2_k127_1685740_54 HNH endonuclease - - - 0.0000000000000000000000000000000000001941 157.0
HKD2_k127_1685740_55 - - - - 0.0000000000000000000000000000000005513 134.0
HKD2_k127_1685740_56 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000001476 137.0
HKD2_k127_1685740_57 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000318 134.0
HKD2_k127_1685740_58 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000007937 131.0
HKD2_k127_1685740_59 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000048 132.0
HKD2_k127_1685740_6 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 551.0
HKD2_k127_1685740_60 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000007101 123.0
HKD2_k127_1685740_61 Beta-lactamase - - - 0.0000000000000000000000006979 115.0
HKD2_k127_1685740_62 - - - - 0.00000000000000000000005058 102.0
HKD2_k127_1685740_63 - - - - 0.000000000000000000002201 94.0
HKD2_k127_1685740_64 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000001015 99.0
HKD2_k127_1685740_65 Domain of unknown function (DUF2017) - - - 0.0000000000000000001339 96.0
HKD2_k127_1685740_66 Thioesterase-like superfamily K07107 - - 0.0000000000000000001504 94.0
HKD2_k127_1685740_67 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000001537 88.0
HKD2_k127_1685740_68 Type II secretion system (T2SS), protein M K02664 - - 0.00000000000000005208 94.0
HKD2_k127_1685740_69 - - - - 0.00000000000003351 74.0
HKD2_k127_1685740_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 479.0
HKD2_k127_1685740_70 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000603 81.0
HKD2_k127_1685740_71 DNA binding domain, excisionase family - - - 0.0000000000004753 72.0
HKD2_k127_1685740_72 - - - - 0.000000000001138 70.0
HKD2_k127_1685740_73 - - - - 0.000000000001612 76.0
HKD2_k127_1685740_74 - - - - 0.00000000001112 69.0
HKD2_k127_1685740_76 Prolyl oligopeptidase family - - - 0.00001004 57.0
HKD2_k127_1685740_77 - - - - 0.00003024 47.0
HKD2_k127_1685740_78 Belongs to the UPF0336 family - - - 0.00003329 51.0
HKD2_k127_1685740_8 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 455.0
HKD2_k127_1685740_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 448.0
HKD2_k127_1695847_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 5.672e-287 912.0
HKD2_k127_1695847_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 6.009e-205 658.0
HKD2_k127_1695847_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 355.0
HKD2_k127_1695847_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
HKD2_k127_1695847_12 Belongs to the enoyl-CoA hydratase isomerase family K01692,K15866 - 4.2.1.17,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 321.0
HKD2_k127_1695847_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
HKD2_k127_1695847_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 308.0
HKD2_k127_1695847_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 309.0
HKD2_k127_1695847_16 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 319.0
HKD2_k127_1695847_17 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 288.0
HKD2_k127_1695847_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
HKD2_k127_1695847_19 Transposase and inactivated derivatives K07498,K18320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
HKD2_k127_1695847_2 efflux transmembrane transporter activity K02004 - - 5.11e-196 638.0
HKD2_k127_1695847_20 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 287.0
HKD2_k127_1695847_21 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001382 266.0
HKD2_k127_1695847_22 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009558 256.0
HKD2_k127_1695847_23 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003125 254.0
HKD2_k127_1695847_24 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000004213 243.0
HKD2_k127_1695847_25 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001685 240.0
HKD2_k127_1695847_26 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000006396 221.0
HKD2_k127_1695847_27 DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000353 208.0
HKD2_k127_1695847_28 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000002295 222.0
HKD2_k127_1695847_29 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000006691 202.0
HKD2_k127_1695847_3 luxR family - - - 1.011e-194 622.0
HKD2_k127_1695847_30 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000001144 189.0
HKD2_k127_1695847_31 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000003848 174.0
HKD2_k127_1695847_32 amino acid K03294 - - 0.00000000000000000000000000000000000000007117 160.0
HKD2_k127_1695847_33 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000005341 153.0
HKD2_k127_1695847_34 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.00000000000000000000000000000000000003224 160.0
HKD2_k127_1695847_35 response to heat K07090 - - 0.00000000000000000000000000000000000003299 153.0
HKD2_k127_1695847_36 - - - - 0.00000000000000000000000000000000000006242 147.0
HKD2_k127_1695847_37 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.0000000000000000000000000000000000003328 148.0
HKD2_k127_1695847_38 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000009268 148.0
HKD2_k127_1695847_39 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000005391 128.0
HKD2_k127_1695847_4 Belongs to the DegT DnrJ EryC1 family K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 538.0
HKD2_k127_1695847_40 methyltransferase - - - 0.000000000000000000000000006907 119.0
HKD2_k127_1695847_41 DsrE/DsrF-like family - - - 0.000000000000000000000007374 113.0
HKD2_k127_1695847_42 - - - - 0.0000000000000000000001963 116.0
HKD2_k127_1695847_43 Metal-sensitive transcriptional repressor - - - 0.0000000000000000000003688 104.0
HKD2_k127_1695847_44 DDE domain - - - 0.000000000000000008232 87.0
HKD2_k127_1695847_45 - - - - 0.00000000000000004798 87.0
HKD2_k127_1695847_46 - - - - 0.0000000000000003489 85.0
HKD2_k127_1695847_47 - - - - 0.000000000000001647 85.0
HKD2_k127_1695847_48 (CsbD) family - - - 0.0000000000000257 79.0
HKD2_k127_1695847_5 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
HKD2_k127_1695847_50 Belongs to the 'phage' integrase family - - - 0.0000000000004187 73.0
HKD2_k127_1695847_51 Histidine kinase - - - 0.0000000008566 63.0
HKD2_k127_1695847_53 - - - - 0.0000005418 56.0
HKD2_k127_1695847_54 Bacterial regulatory proteins, tetR family - - - 0.000008394 56.0
HKD2_k127_1695847_55 Phosphate acyltransferases K00655 - 2.3.1.51 0.00002059 54.0
HKD2_k127_1695847_56 membrane protein (DUF2078) K08982 - - 0.00003241 56.0
HKD2_k127_1695847_57 - - - - 0.0004444 48.0
HKD2_k127_1695847_6 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 419.0
HKD2_k127_1695847_7 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 392.0
HKD2_k127_1695847_8 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 403.0
HKD2_k127_1695847_9 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 385.0
HKD2_k127_1796571_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 495.0
HKD2_k127_1796571_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 460.0
HKD2_k127_1796571_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 307.0
HKD2_k127_1796571_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 299.0
HKD2_k127_1796571_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002045 285.0
HKD2_k127_1796571_5 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000001872 169.0
HKD2_k127_1796571_6 PAS domain - - - 0.000000000000000000000000000000000000000002372 160.0
HKD2_k127_1796571_7 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000005837 135.0
HKD2_k127_218825_0 PFAM acyl-CoA dehydrogenase domain protein - - - 5.924e-307 968.0
HKD2_k127_218825_1 STAS domain K03321 - - 3.581e-229 723.0
HKD2_k127_218825_10 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 362.0
HKD2_k127_218825_11 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 345.0
HKD2_k127_218825_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 332.0
HKD2_k127_218825_13 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
HKD2_k127_218825_14 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 320.0
HKD2_k127_218825_15 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003141 267.0
HKD2_k127_218825_16 Siderophore-interacting FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001354 212.0
HKD2_k127_218825_17 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000002 203.0
HKD2_k127_218825_18 protein hemolysin III K11068 - - 0.000000000000000000000000000000000000000002011 164.0
HKD2_k127_218825_19 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000002866 138.0
HKD2_k127_218825_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 503.0
HKD2_k127_218825_20 Limonene-12-epoxide hydrolase K10533 - 3.3.2.8 0.00000000000000000000000008755 121.0
HKD2_k127_218825_21 Carotene biosynthesis associated membrane protein - - - 0.0000000000000002049 94.0
HKD2_k127_218825_22 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.00000000008066 76.0
HKD2_k127_218825_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 492.0
HKD2_k127_218825_4 Glycosyl transferase family group 2 K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 460.0
HKD2_k127_218825_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 440.0
HKD2_k127_218825_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 416.0
HKD2_k127_218825_7 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 420.0
HKD2_k127_218825_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 392.0
HKD2_k127_218825_9 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 397.0
HKD2_k127_223108_0 SMART Elongator protein 3 MiaB NifB K11779 - 2.5.1.77 0.0 1011.0
HKD2_k127_223108_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.878e-225 717.0
HKD2_k127_223108_10 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 485.0
HKD2_k127_223108_11 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 465.0
HKD2_k127_223108_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 481.0
HKD2_k127_223108_13 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 464.0
HKD2_k127_223108_14 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 471.0
HKD2_k127_223108_15 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 447.0
HKD2_k127_223108_16 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 435.0
HKD2_k127_223108_17 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 408.0
HKD2_k127_223108_18 Alpha/beta hydrolase family - GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 405.0
HKD2_k127_223108_19 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 390.0
HKD2_k127_223108_2 CoA binding domain - - - 4.808e-220 693.0
HKD2_k127_223108_20 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 390.0
HKD2_k127_223108_21 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 393.0
HKD2_k127_223108_22 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 376.0
HKD2_k127_223108_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 377.0
HKD2_k127_223108_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 380.0
HKD2_k127_223108_25 5'-3' exonuclease, C-terminal SAM fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 364.0
HKD2_k127_223108_26 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 356.0
HKD2_k127_223108_27 Dienelactone hydrolase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 358.0
HKD2_k127_223108_28 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 357.0
HKD2_k127_223108_29 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 329.0
HKD2_k127_223108_3 COG2015, Alkyl sulfatase and related hydrolases - - - 2.069e-208 665.0
HKD2_k127_223108_30 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 321.0
HKD2_k127_223108_31 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 336.0
HKD2_k127_223108_32 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 316.0
HKD2_k127_223108_33 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
HKD2_k127_223108_34 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 314.0
HKD2_k127_223108_35 PFAM FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 317.0
HKD2_k127_223108_36 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 309.0
HKD2_k127_223108_37 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001879 308.0
HKD2_k127_223108_38 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006602 288.0
HKD2_k127_223108_39 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006208 294.0
HKD2_k127_223108_4 Glycine D-amino acid oxidases (deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 570.0
HKD2_k127_223108_40 PFAM RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001004 276.0
HKD2_k127_223108_41 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001529 255.0
HKD2_k127_223108_43 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000000005421 236.0
HKD2_k127_223108_44 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000006017 239.0
HKD2_k127_223108_45 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000002375 248.0
HKD2_k127_223108_46 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003694 230.0
HKD2_k127_223108_47 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004103 233.0
HKD2_k127_223108_48 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
HKD2_k127_223108_49 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001126 241.0
HKD2_k127_223108_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 557.0
HKD2_k127_223108_50 Domain of unknown function (DUF1794) - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
HKD2_k127_223108_51 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000835 219.0
HKD2_k127_223108_52 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000002847 199.0
HKD2_k127_223108_53 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000002194 188.0
HKD2_k127_223108_55 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000007918 188.0
HKD2_k127_223108_56 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000002128 193.0
HKD2_k127_223108_57 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000709 181.0
HKD2_k127_223108_58 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000003385 172.0
HKD2_k127_223108_59 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.00000000000000000000000000000000000000000003785 169.0
HKD2_k127_223108_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 566.0
HKD2_k127_223108_60 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000002606 175.0
HKD2_k127_223108_61 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000001151 164.0
HKD2_k127_223108_62 Transcriptional regulator - - - 0.000000000000000000000000000000000000132 148.0
HKD2_k127_223108_63 FAD binding domain K11472 - - 0.000000000000000000000000000000000001045 160.0
HKD2_k127_223108_64 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.000000000000000000000000000000000001438 151.0
HKD2_k127_223108_65 transcriptional regulator - - - 0.000000000000000000000000000000000001895 145.0
HKD2_k127_223108_66 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000006005 144.0
HKD2_k127_223108_67 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000003592 136.0
HKD2_k127_223108_68 YCII-related domain - - - 0.000000000000000000000000000000001392 149.0
HKD2_k127_223108_69 PFAM NLP P60 protein K21471 GO:0005575,GO:0005576 - 0.000000000000000000000000000000001544 147.0
HKD2_k127_223108_7 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 554.0
HKD2_k127_223108_70 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000006508 130.0
HKD2_k127_223108_71 Initiation factor 2 subunit family - - - 0.000000000000000000000000003466 122.0
HKD2_k127_223108_72 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000000000000000000000003473 118.0
HKD2_k127_223108_73 U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.000000000000000000000000829 117.0
HKD2_k127_223108_74 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000008488 103.0
HKD2_k127_223108_75 glycosyl transferase family 2 - - - 0.0000000000000000000006752 105.0
HKD2_k127_223108_76 ThiS family K03154 - - 0.000000000000001822 78.0
HKD2_k127_223108_77 Prenyltransferase and squalene oxidase repeat - - - 0.000000000005452 77.0
HKD2_k127_223108_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 531.0
HKD2_k127_223108_9 dioxygenase K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 490.0
HKD2_k127_2329106_0 Required for chromosome condensation and partitioning K03529 - - 6.464e-276 889.0
HKD2_k127_2329106_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 553.0
HKD2_k127_2329106_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 327.0
HKD2_k127_2329106_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007672 297.0
HKD2_k127_2329106_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 300.0
HKD2_k127_2329106_13 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 295.0
HKD2_k127_2329106_14 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000004848 269.0
HKD2_k127_2329106_15 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001061 257.0
HKD2_k127_2329106_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000036 233.0
HKD2_k127_2329106_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000006533 221.0
HKD2_k127_2329106_18 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.00000000000000000000000000000000000000000000000000000000000001741 226.0
HKD2_k127_2329106_19 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.0000000000000000000000000000000000000000000000000000000000000611 233.0
HKD2_k127_2329106_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 524.0
HKD2_k127_2329106_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000001376 226.0
HKD2_k127_2329106_21 Peptidase family M50 K11749 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000428 224.0
HKD2_k127_2329106_22 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000003588 213.0
HKD2_k127_2329106_23 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000001098 206.0
HKD2_k127_2329106_24 - - - - 0.000000000000000000000000000000000000000000000000000003902 196.0
HKD2_k127_2329106_25 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000002176 186.0
HKD2_k127_2329106_26 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000001483 195.0
HKD2_k127_2329106_27 COG4974 Site-specific recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000009816 179.0
HKD2_k127_2329106_28 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000001241 169.0
HKD2_k127_2329106_29 ATP synthesis coupled proton transport - - - 0.0000000000000000000000000000000000000003371 155.0
HKD2_k127_2329106_3 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 499.0
HKD2_k127_2329106_30 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001046 153.0
HKD2_k127_2329106_31 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000001139 150.0
HKD2_k127_2329106_32 CTP:tRNA cytidylyltransferase activity K00970,K00974,K19545 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000002209 151.0
HKD2_k127_2329106_33 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000009185 145.0
HKD2_k127_2329106_34 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000002835 147.0
HKD2_k127_2329106_35 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000002048 122.0
HKD2_k127_2329106_36 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000002785 131.0
HKD2_k127_2329106_37 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000003091 120.0
HKD2_k127_2329106_38 Ribosomal protein S16 K02959 - - 0.00000000000000000000000004301 114.0
HKD2_k127_2329106_39 - - - - 0.00000000000000000000000004461 122.0
HKD2_k127_2329106_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 454.0
HKD2_k127_2329106_40 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000006173 113.0
HKD2_k127_2329106_41 - - - - 0.000000000000000000002404 107.0
HKD2_k127_2329106_42 PFAM peptidase - - - 0.0000000000000000006637 102.0
HKD2_k127_2329106_43 ATP- GTP-binding protein - - - 0.00000000000000001178 86.0
HKD2_k127_2329106_44 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000818 81.0
HKD2_k127_2329106_45 Cold shock K03704 - - 0.0000000000000002363 83.0
HKD2_k127_2329106_46 Protein of unknown function (DUF2510) - - - 0.000000009771 65.0
HKD2_k127_2329106_47 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.0000002203 61.0
HKD2_k127_2329106_5 PFAM Magnesium chelatase, ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 411.0
HKD2_k127_2329106_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 401.0
HKD2_k127_2329106_7 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 361.0
HKD2_k127_2329106_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 357.0
HKD2_k127_2329106_9 Mur ligase, middle domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 340.0
HKD2_k127_2482513_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 4.2.1.33,4.2.1.35 8.174e-232 724.0
HKD2_k127_2482513_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.965e-224 707.0
HKD2_k127_2482513_10 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 407.0
HKD2_k127_2482513_11 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 361.0
HKD2_k127_2482513_12 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 352.0
HKD2_k127_2482513_13 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 323.0
HKD2_k127_2482513_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 311.0
HKD2_k127_2482513_15 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
HKD2_k127_2482513_16 Zn-dependent K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 283.0
HKD2_k127_2482513_17 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001888 284.0
HKD2_k127_2482513_18 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003197 290.0
HKD2_k127_2482513_19 Transcriptional regulatory protein, C terminal K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000163 276.0
HKD2_k127_2482513_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.205e-197 629.0
HKD2_k127_2482513_20 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000009898 257.0
HKD2_k127_2482513_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000009951 246.0
HKD2_k127_2482513_22 His Kinase A (phosphoacceptor) domain K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001488 264.0
HKD2_k127_2482513_23 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000004188 245.0
HKD2_k127_2482513_24 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000005199 218.0
HKD2_k127_2482513_25 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000007644 213.0
HKD2_k127_2482513_26 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000002447 209.0
HKD2_k127_2482513_27 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000001524 198.0
HKD2_k127_2482513_28 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.000000000000000000000000000000000000000000001572 180.0
HKD2_k127_2482513_29 arylsulfatase activity - - - 0.000000000000000000000000000000000000000006708 178.0
HKD2_k127_2482513_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 608.0
HKD2_k127_2482513_30 membrane - - - 0.000000000000000000000000000000000000003054 154.0
HKD2_k127_2482513_31 transcriptional regulator - - - 0.000000000000000000000000000000000000003286 154.0
HKD2_k127_2482513_32 adenosine 5'-monophosphoramidase activity - - - 0.000000000000000000000000000000000000004165 152.0
HKD2_k127_2482513_33 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001087 154.0
HKD2_k127_2482513_34 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000001163 154.0
HKD2_k127_2482513_35 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.00000000000000000000000000000000000001923 162.0
HKD2_k127_2482513_36 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000001428 145.0
HKD2_k127_2482513_37 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000005085 147.0
HKD2_k127_2482513_38 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000007331 147.0
HKD2_k127_2482513_39 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000003519 136.0
HKD2_k127_2482513_4 alcohol dehydrogenase K00153 - 1.1.1.306 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 593.0
HKD2_k127_2482513_40 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000004278 145.0
HKD2_k127_2482513_41 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000007577 134.0
HKD2_k127_2482513_42 - - - - 0.0000000000000000000000000000001822 131.0
HKD2_k127_2482513_43 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000000000000000000000007082 137.0
HKD2_k127_2482513_44 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000001469 132.0
HKD2_k127_2482513_45 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.000000000000000000000000000009808 135.0
HKD2_k127_2482513_46 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.0000000000000000000000002337 111.0
HKD2_k127_2482513_47 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000001151 111.0
HKD2_k127_2482513_48 YceI-like domain - - - 0.00000000000000000004539 102.0
HKD2_k127_2482513_5 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 588.0
HKD2_k127_2482513_50 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000004368 91.0
HKD2_k127_2482513_51 nuclease K01174 - 3.1.31.1 0.000000000001867 73.0
HKD2_k127_2482513_53 OsmC-like protein - - - 0.00000004649 61.0
HKD2_k127_2482513_6 SEC-C motif K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
HKD2_k127_2482513_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 514.0
HKD2_k127_2482513_8 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 454.0
HKD2_k127_2482513_9 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 442.0
HKD2_k127_2506328_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 487.0
HKD2_k127_2506328_1 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 391.0
HKD2_k127_2506328_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 332.0
HKD2_k127_2506328_3 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001359 298.0
HKD2_k127_2506328_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
HKD2_k127_2506328_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000001063 196.0
HKD2_k127_2506328_6 Acyl-transferase K00655,K14598 - 2.3.1.51 0.0000000000000000000000000000000000000000000003399 193.0
HKD2_k127_2506328_7 2 iron, 2 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000005453 173.0
HKD2_k127_2506328_8 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000002676 160.0
HKD2_k127_2506328_9 - - - - 0.000000000000000000000000555 109.0
HKD2_k127_2579968_0 DNA polymerase alpha chain like domain K02337 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.7 0.0 1483.0
HKD2_k127_2579968_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1052.0
HKD2_k127_2579968_10 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 514.0
HKD2_k127_2579968_11 PFAM aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 507.0
HKD2_k127_2579968_12 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 471.0
HKD2_k127_2579968_13 tRNA synthetases class I (C) catalytic domain K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 464.0
HKD2_k127_2579968_14 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 458.0
HKD2_k127_2579968_15 Cytochrome P450 K15981 - 1.14.13.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 422.0
HKD2_k127_2579968_16 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 396.0
HKD2_k127_2579968_17 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 394.0
HKD2_k127_2579968_18 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 396.0
HKD2_k127_2579968_19 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 390.0
HKD2_k127_2579968_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.257e-292 939.0
HKD2_k127_2579968_20 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 369.0
HKD2_k127_2579968_21 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 368.0
HKD2_k127_2579968_22 Glycosyl transferases group 1 K13668 GO:0000009,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0033164,GO:0040007,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 366.0
HKD2_k127_2579968_23 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 354.0
HKD2_k127_2579968_24 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 370.0
HKD2_k127_2579968_25 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 359.0
HKD2_k127_2579968_26 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 360.0
HKD2_k127_2579968_27 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 339.0
HKD2_k127_2579968_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 333.0
HKD2_k127_2579968_29 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
HKD2_k127_2579968_3 CoA-binding domain protein - - - 1.103e-238 762.0
HKD2_k127_2579968_30 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 314.0
HKD2_k127_2579968_31 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 310.0
HKD2_k127_2579968_32 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 316.0
HKD2_k127_2579968_33 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 319.0
HKD2_k127_2579968_34 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 296.0
HKD2_k127_2579968_35 Belongs to the SEDS family K02563,K03588 GO:0008150,GO:0040007 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004243 279.0
HKD2_k127_2579968_36 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009685 276.0
HKD2_k127_2579968_37 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 293.0
HKD2_k127_2579968_38 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000007058 262.0
HKD2_k127_2579968_39 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003867 260.0
HKD2_k127_2579968_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 6.073e-214 677.0
HKD2_k127_2579968_40 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001373 268.0
HKD2_k127_2579968_41 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000004218 253.0
HKD2_k127_2579968_42 ROK family K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000005703 251.0
HKD2_k127_2579968_43 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005772 257.0
HKD2_k127_2579968_44 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000007014 241.0
HKD2_k127_2579968_45 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000008175 248.0
HKD2_k127_2579968_46 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002951 230.0
HKD2_k127_2579968_47 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000007081 227.0
HKD2_k127_2579968_48 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000007375 225.0
HKD2_k127_2579968_49 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000002328 241.0
HKD2_k127_2579968_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 616.0
HKD2_k127_2579968_50 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000008062 213.0
HKD2_k127_2579968_51 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000008992 222.0
HKD2_k127_2579968_52 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000166 209.0
HKD2_k127_2579968_53 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000003784 220.0
HKD2_k127_2579968_54 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000008543 210.0
HKD2_k127_2579968_55 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000004599 184.0
HKD2_k127_2579968_56 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000001057 190.0
HKD2_k127_2579968_57 endonuclease - - - 0.0000000000000000000000000000000000000000000001177 191.0
HKD2_k127_2579968_58 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000001268 176.0
HKD2_k127_2579968_59 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000057 179.0
HKD2_k127_2579968_6 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 586.0
HKD2_k127_2579968_60 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000001108 171.0
HKD2_k127_2579968_61 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000002112 169.0
HKD2_k127_2579968_62 methyltransferase - - - 0.0000000000000000000000000000000000000000002744 176.0
HKD2_k127_2579968_63 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000001684 169.0
HKD2_k127_2579968_64 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000006831 165.0
HKD2_k127_2579968_65 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944 - 0.0000000000000000000000000000000000000003637 159.0
HKD2_k127_2579968_66 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.00000000000000000000000000000000008668 141.0
HKD2_k127_2579968_67 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000008799 140.0
HKD2_k127_2579968_68 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000001097 149.0
HKD2_k127_2579968_69 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.4.23.36 0.000000000000000000000000000000003977 135.0
HKD2_k127_2579968_7 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 578.0
HKD2_k127_2579968_70 phosphoglycerate mutase - - - 0.00000000000000000000000000000002992 139.0
HKD2_k127_2579968_71 transcriptional regulator K22107 - - 0.0000000000000000000000000000001682 134.0
HKD2_k127_2579968_72 phosphatase activity K07025 - - 0.0000000000000000000000000000005369 142.0
HKD2_k127_2579968_73 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000002018 127.0
HKD2_k127_2579968_74 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000000001166 126.0
HKD2_k127_2579968_75 - - - - 0.00000000000000000000000000009187 135.0
HKD2_k127_2579968_76 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000001788 127.0
HKD2_k127_2579968_77 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000005419 126.0
HKD2_k127_2579968_78 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000001876 127.0
HKD2_k127_2579968_79 electron transfer activity K05337 - - 0.00000000000000000000000003698 109.0
HKD2_k127_2579968_8 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 557.0
HKD2_k127_2579968_80 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000005226 116.0
HKD2_k127_2579968_82 transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000001075 100.0
HKD2_k127_2579968_83 Protein of unknown function (DUF3040) - - - 0.00000000000000000002202 105.0
HKD2_k127_2579968_84 Oxidoreductase family, C-terminal alpha/beta domain K00010,K16044 - 1.1.1.18,1.1.1.369,1.1.1.371 0.00000000000000000003897 104.0
HKD2_k127_2579968_85 transcriptional - - - 0.0000000000000001955 89.0
HKD2_k127_2579968_86 POTRA domain, FtsQ-type K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000009387 90.0
HKD2_k127_2579968_87 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04091 - 1.14.14.5 0.000000000000004872 85.0
HKD2_k127_2579968_88 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000009189 89.0
HKD2_k127_2579968_89 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000001264 80.0
HKD2_k127_2579968_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 519.0
HKD2_k127_2579968_90 regulation of cell shape - - - 0.0000000006553 71.0
HKD2_k127_2579968_91 Integral membrane protein K02221 - - 0.00000001642 58.0
HKD2_k127_2579968_92 - - - - 0.000003047 55.0
HKD2_k127_2579968_94 HNH nucleases - - - 0.0009232 51.0
HKD2_k127_2641595_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 5.954e-210 677.0
HKD2_k127_2641595_1 Protein of unknown function, DUF255 K06888 - - 6.517e-198 637.0
HKD2_k127_2641595_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 337.0
HKD2_k127_2641595_11 dipeptidase activity K14358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 297.0
HKD2_k127_2641595_12 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000005857 236.0
HKD2_k127_2641595_13 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
HKD2_k127_2641595_14 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003948 258.0
HKD2_k127_2641595_15 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002055 229.0
HKD2_k127_2641595_16 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
HKD2_k127_2641595_17 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.0000000000000000000000000000000000000000000000006788 188.0
HKD2_k127_2641595_18 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000002779 181.0
HKD2_k127_2641595_19 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000005771 149.0
HKD2_k127_2641595_2 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 638.0
HKD2_k127_2641595_20 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000208 157.0
HKD2_k127_2641595_21 - - - - 0.0000000000000000000000000000000005931 142.0
HKD2_k127_2641595_22 Aminomethyltransferase folate-binding domain K06980 - - 0.00000000000000000000000000000002115 145.0
HKD2_k127_2641595_23 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000000000000001489 116.0
HKD2_k127_2641595_24 light absorption K01822 - 5.3.3.1 0.0000000000000000000004056 100.0
HKD2_k127_2641595_25 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000004526 63.0
HKD2_k127_2641595_27 - - - - 0.0000000003442 63.0
HKD2_k127_2641595_3 Anthranilate synthase component 1 K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 549.0
HKD2_k127_2641595_4 Peptidase M3A and M3B thimet oligopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 427.0
HKD2_k127_2641595_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 391.0
HKD2_k127_2641595_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HKD2_k127_2641595_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 381.0
HKD2_k127_2641595_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 338.0
HKD2_k127_2641595_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 345.0
HKD2_k127_2712387_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008897 261.0
HKD2_k127_2712387_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000004715 231.0
HKD2_k127_2712387_2 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000002687 211.0
HKD2_k127_2712387_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000002745 203.0
HKD2_k127_2712387_4 transcriptional regulator - - - 0.0000000000000000000000000000003955 124.0
HKD2_k127_2712387_5 PKD domain - - - 0.000000000000000000000001136 121.0
HKD2_k127_2712387_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000002988 74.0
HKD2_k127_2712387_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00007076 54.0
HKD2_k127_2717132_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 570.0
HKD2_k127_2717132_1 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 302.0
HKD2_k127_2717132_10 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000005352 129.0
HKD2_k127_2717132_11 Ferredoxin - - - 0.000000000000000000006961 97.0
HKD2_k127_2717132_12 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000006223 89.0
HKD2_k127_2717132_13 Protein of unknown function (DUF2795) - - - 0.0000000000000000991 94.0
HKD2_k127_2717132_14 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000004347 92.0
HKD2_k127_2717132_15 - - - - 0.0000000000006492 72.0
HKD2_k127_2717132_16 protein phosphatase 2C domain protein - - - 0.0000000000008312 76.0
HKD2_k127_2717132_18 PFAM glycosyl transferase family 9 - - - 0.0000000001685 66.0
HKD2_k127_2717132_19 CsbD-like - - - 0.000000000237 66.0
HKD2_k127_2717132_2 protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000032 289.0
HKD2_k127_2717132_20 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000001427 65.0
HKD2_k127_2717132_22 Conserved Protein - - - 0.00000001657 64.0
HKD2_k127_2717132_23 antisigma factor binding - - - 0.00000002209 60.0
HKD2_k127_2717132_24 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000001002 65.0
HKD2_k127_2717132_25 - - - - 0.0000006143 52.0
HKD2_k127_2717132_26 - - - - 0.0005507 48.0
HKD2_k127_2717132_3 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001633 252.0
HKD2_k127_2717132_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000189 231.0
HKD2_k127_2717132_5 Encapsulating protein for peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000008078 234.0
HKD2_k127_2717132_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000002151 232.0
HKD2_k127_2717132_7 RNA polymerase sigma factor, sigma-70 family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001259 227.0
HKD2_k127_2717132_8 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000005938 177.0
HKD2_k127_2717132_9 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000002056 143.0
HKD2_k127_2762491_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 8.86e-240 753.0
HKD2_k127_2762491_1 sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 574.0
HKD2_k127_2762491_10 - - - - 0.000000000000000000000000000000000000000000000000001301 195.0
HKD2_k127_2762491_11 - - - - 0.0000000000000000000000000000000000000001475 154.0
HKD2_k127_2762491_12 Domain of unknown function DUF302 - - - 0.00000000000000000000000004447 113.0
HKD2_k127_2762491_2 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 545.0
HKD2_k127_2762491_3 beta-lactamase domain protein K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 488.0
HKD2_k127_2762491_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 474.0
HKD2_k127_2762491_5 sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 425.0
HKD2_k127_2762491_6 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 379.0
HKD2_k127_2762491_7 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000141 252.0
HKD2_k127_2762491_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004 237.0
HKD2_k127_2762491_9 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000007488 204.0
HKD2_k127_2833051_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.0 1227.0
HKD2_k127_2833051_1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 1.072e-249 802.0
HKD2_k127_2833051_10 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 297.0
HKD2_k127_2833051_11 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 303.0
HKD2_k127_2833051_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
HKD2_k127_2833051_13 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000005951 207.0
HKD2_k127_2833051_14 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000005515 200.0
HKD2_k127_2833051_15 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000167 192.0
HKD2_k127_2833051_16 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000002277 179.0
HKD2_k127_2833051_17 Zn peptidase - - - 0.0000000000000000000000000000000000000000000008607 181.0
HKD2_k127_2833051_18 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000116 170.0
HKD2_k127_2833051_19 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000003126 172.0
HKD2_k127_2833051_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 1.135e-198 625.0
HKD2_k127_2833051_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000006386 166.0
HKD2_k127_2833051_21 (FHA) domain - - - 0.0000000000000000000000000000000000000000001896 162.0
HKD2_k127_2833051_22 AAA domain - - - 0.0000000000000000000000000000000000000000005636 168.0
HKD2_k127_2833051_23 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000004742 166.0
HKD2_k127_2833051_24 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000003937 166.0
HKD2_k127_2833051_25 OsmC-like protein - - - 0.00000000000000000000000000000000000005406 147.0
HKD2_k127_2833051_26 transferase activity, transferring glycosyl groups K13500 - 2.4.1.175,2.4.1.226 0.000000000000000000000000000000000001724 153.0
HKD2_k127_2833051_27 - - - - 0.00000000003063 73.0
HKD2_k127_2833051_28 Beta-lactamase - - - 0.0000000001314 67.0
HKD2_k127_2833051_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 467.0
HKD2_k127_2833051_30 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000402 49.0
HKD2_k127_2833051_4 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 417.0
HKD2_k127_2833051_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 400.0
HKD2_k127_2833051_6 von Willebrand factor (vWF) type A domain K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 372.0
HKD2_k127_2833051_7 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 357.0
HKD2_k127_2833051_8 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 361.0
HKD2_k127_2833051_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 329.0
HKD2_k127_2835322_0 Flavoprotein involved in K transport - - - 1.035e-235 745.0
HKD2_k127_2835322_1 COG0433 Predicted ATPase K06915 - - 2.064e-235 743.0
HKD2_k127_2835322_10 AMP-binding enzyme C-terminal domain K18688 - 6.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 458.0
HKD2_k127_2835322_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 438.0
HKD2_k127_2835322_12 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 419.0
HKD2_k127_2835322_13 FAD binding domain K16051 - 1.3.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 436.0
HKD2_k127_2835322_14 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 432.0
HKD2_k127_2835322_15 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 385.0
HKD2_k127_2835322_16 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 379.0
HKD2_k127_2835322_17 Belongs to the glycosyl hydrolase 5 (cellulase A) family K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 364.0
HKD2_k127_2835322_18 Enoyl-(Acyl carrier protein) reductase K00076 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 324.0
HKD2_k127_2835322_19 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 328.0
HKD2_k127_2835322_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 5.369e-200 639.0
HKD2_k127_2835322_20 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 312.0
HKD2_k127_2835322_21 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 292.0
HKD2_k127_2835322_22 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 302.0
HKD2_k127_2835322_23 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008731 286.0
HKD2_k127_2835322_24 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
HKD2_k127_2835322_25 COGs COG2380 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001122 262.0
HKD2_k127_2835322_26 Zc3h12a-like Ribonuclease NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002845 281.0
HKD2_k127_2835322_27 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000008355 243.0
HKD2_k127_2835322_28 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001915 217.0
HKD2_k127_2835322_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000001215 200.0
HKD2_k127_2835322_3 Amidohydrolase family - - - 1.218e-194 646.0
HKD2_k127_2835322_30 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000006123 193.0
HKD2_k127_2835322_31 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000001477 181.0
HKD2_k127_2835322_32 Alpha beta - - - 0.000000000000000000000000000000000000002239 159.0
HKD2_k127_2835322_33 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000002058 156.0
HKD2_k127_2835322_34 by modhmm - - - 0.00000000000000000000000000000000006626 153.0
HKD2_k127_2835322_35 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000001928 145.0
HKD2_k127_2835322_36 - - - - 0.0000000000000000000000000000000008205 145.0
HKD2_k127_2835322_37 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000001393 119.0
HKD2_k127_2835322_38 methyltransferase - - - 0.00000000000000000000000002563 116.0
HKD2_k127_2835322_39 PEP-utilising enzyme, mobile domain - - - 0.0000000000000000000001361 107.0
HKD2_k127_2835322_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 572.0
HKD2_k127_2835322_40 acid phosphatase activity - - - 0.000000000000000000001149 111.0
HKD2_k127_2835322_41 Rhodanese Homology Domain - - - 0.00000000000000000002026 101.0
HKD2_k127_2835322_42 PEP-utilising enzyme, mobile domain - - - 0.0000000000000002856 86.0
HKD2_k127_2835322_43 - - - - 0.00000003295 64.0
HKD2_k127_2835322_44 Aminoglycoside phosphotransferase - - - 0.00000005989 60.0
HKD2_k127_2835322_45 CARDB - - - 0.000002387 60.0
HKD2_k127_2835322_46 Membrane - - - 0.000009304 59.0
HKD2_k127_2835322_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 517.0
HKD2_k127_2835322_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 525.0
HKD2_k127_2835322_7 FAD linked K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 515.0
HKD2_k127_2835322_8 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 492.0
HKD2_k127_2835322_9 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 482.0
HKD2_k127_3027273_0 AcrB/AcrD/AcrF family - - - 0.0 1163.0
HKD2_k127_3027273_1 AcrB/AcrD/AcrF family - - - 5.931e-256 826.0
HKD2_k127_3027273_10 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 307.0
HKD2_k127_3027273_11 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 302.0
HKD2_k127_3027273_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 301.0
HKD2_k127_3027273_13 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009161 286.0
HKD2_k127_3027273_14 PFAM ParB domain protein nuclease K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007141 263.0
HKD2_k127_3027273_15 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
HKD2_k127_3027273_16 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
HKD2_k127_3027273_17 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000009302 228.0
HKD2_k127_3027273_18 - - - - 0.000000000000000000000000000000000000000000000000000003247 205.0
HKD2_k127_3027273_19 Single-strand binding protein family K03111 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000003996 181.0
HKD2_k127_3027273_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.209e-196 617.0
HKD2_k127_3027273_20 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000000000000000000000007557 182.0
HKD2_k127_3027273_21 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000003374 180.0
HKD2_k127_3027273_22 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000002003 180.0
HKD2_k127_3027273_23 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000002346 149.0
HKD2_k127_3027273_24 PFAM ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000292 166.0
HKD2_k127_3027273_25 60Kd inner membrane protein K03217 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000704 158.0
HKD2_k127_3027273_26 methyltransferase - - - 0.000000000000000000000000000000000000008263 154.0
HKD2_k127_3027273_27 acetyltransferase - - - 0.0000000000000000000000000000000000006258 154.0
HKD2_k127_3027273_28 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000007425 138.0
HKD2_k127_3027273_29 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000004529 143.0
HKD2_k127_3027273_3 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 545.0
HKD2_k127_3027273_30 - - - - 0.000000000000000000000000000000002459 141.0
HKD2_k127_3027273_31 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.000000000000000000000000000000007756 140.0
HKD2_k127_3027273_32 transcriptional regulator PadR family - - - 0.0000000000000000000000000000003174 131.0
HKD2_k127_3027273_33 Family of unknown function (DUF5318) - - - 0.0000000000000000000000000009476 119.0
HKD2_k127_3027273_34 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000006246 107.0
HKD2_k127_3027273_35 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003156 105.0
HKD2_k127_3027273_36 SnoaL-like domain - - - 0.000000000000000000000192 108.0
HKD2_k127_3027273_37 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000006787 98.0
HKD2_k127_3027273_38 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000018 76.0
HKD2_k127_3027273_39 - - - - 0.0000000002096 74.0
HKD2_k127_3027273_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 430.0
HKD2_k127_3027273_42 cytochrome - - - 0.00004316 54.0
HKD2_k127_3027273_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 421.0
HKD2_k127_3027273_6 Pyridine nucleotide-disulphide oxidoreductase K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 417.0
HKD2_k127_3027273_7 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 376.0
HKD2_k127_3027273_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 339.0
HKD2_k127_3027273_9 MviN-like protein K03980 GO:0003674,GO:0005215,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 325.0
HKD2_k127_3266693_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1067.0
HKD2_k127_3266693_1 4Fe-4S dicluster domain - - - 0.0 1028.0
HKD2_k127_3266693_10 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 466.0
HKD2_k127_3266693_11 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 451.0
HKD2_k127_3266693_12 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 419.0
HKD2_k127_3266693_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 372.0
HKD2_k127_3266693_14 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 357.0
HKD2_k127_3266693_15 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 349.0
HKD2_k127_3266693_16 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 339.0
HKD2_k127_3266693_17 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 333.0
HKD2_k127_3266693_18 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
HKD2_k127_3266693_19 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 310.0
HKD2_k127_3266693_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.543e-269 849.0
HKD2_k127_3266693_20 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 288.0
HKD2_k127_3266693_21 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 307.0
HKD2_k127_3266693_22 ATP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004706 297.0
HKD2_k127_3266693_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006613 263.0
HKD2_k127_3266693_24 Exopolysaccharide production protein K00996,K16566 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.6 0.0000000000000000000000000000000000000000000000000000000000007765 224.0
HKD2_k127_3266693_25 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000001984 156.0
HKD2_k127_3266693_26 helix_turn_helix, mercury resistance K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000002577 132.0
HKD2_k127_3266693_27 - - - - 0.00000000000000000000000000001284 127.0
HKD2_k127_3266693_28 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000003705 128.0
HKD2_k127_3266693_29 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000004672 119.0
HKD2_k127_3266693_3 Heat shock 70 kDa protein K04043 - - 7.217e-263 824.0
HKD2_k127_3266693_30 cyclic nucleotide binding K10914 - - 0.000000000000000000000000006066 129.0
HKD2_k127_3266693_31 cyclic nucleotide binding K10914 - - 0.00000000000000000000009577 103.0
HKD2_k127_3266693_32 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.00000000000000000001776 100.0
HKD2_k127_3266693_33 Helix-turn-helix domain - - - 0.000000000000000178 89.0
HKD2_k127_3266693_34 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000004115 85.0
HKD2_k127_3266693_35 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000002792 72.0
HKD2_k127_3266693_36 AAA domain - - - 0.0000000000004885 78.0
HKD2_k127_3266693_38 Chain length determinant protein K08252,K16692 - 2.7.10.1 0.00000000002571 76.0
HKD2_k127_3266693_39 Lamin Tail Domain K07004 - - 0.0000001899 64.0
HKD2_k127_3266693_4 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 603.0
HKD2_k127_3266693_40 Bacterial regulatory proteins, tetR family - - - 0.0000006786 58.0
HKD2_k127_3266693_41 - - - - 0.000006919 55.0
HKD2_k127_3266693_42 transcriptional regulator - - - 0.0006154 51.0
HKD2_k127_3266693_5 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 554.0
HKD2_k127_3266693_6 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 527.0
HKD2_k127_3266693_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 517.0
HKD2_k127_3266693_8 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 501.0
HKD2_k127_3266693_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 490.0
HKD2_k127_3466600_0 DNA Topoisomerase IV K02469 - 5.99.1.3 1.286e-281 887.0
HKD2_k127_3466600_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 7.31e-235 745.0
HKD2_k127_3466600_10 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 339.0
HKD2_k127_3466600_11 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 336.0
HKD2_k127_3466600_12 Penicillin binding protein transpeptidase domain K05364 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 332.0
HKD2_k127_3466600_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 320.0
HKD2_k127_3466600_14 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 317.0
HKD2_k127_3466600_15 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 314.0
HKD2_k127_3466600_16 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 321.0
HKD2_k127_3466600_17 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000838 267.0
HKD2_k127_3466600_18 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001692 275.0
HKD2_k127_3466600_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001121 266.0
HKD2_k127_3466600_2 protoporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 483.0
HKD2_k127_3466600_20 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000003946 229.0
HKD2_k127_3466600_21 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000003597 214.0
HKD2_k127_3466600_22 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000007187 218.0
HKD2_k127_3466600_23 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000007343 215.0
HKD2_k127_3466600_24 Limonene-12-epoxide hydrolase - - - 0.00000000000000000000000000000000000000000000000002891 183.0
HKD2_k127_3466600_25 Belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.000000000000000000000000000000000000000000000001646 184.0
HKD2_k127_3466600_26 A G-specific K03575 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000481 191.0
HKD2_k127_3466600_27 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000004081 172.0
HKD2_k127_3466600_28 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.0000000000000000000000000000000000000001367 156.0
HKD2_k127_3466600_29 PAP2 superfamily - - - 0.00000000000000000000000000000000001755 148.0
HKD2_k127_3466600_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 469.0
HKD2_k127_3466600_30 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000003748 132.0
HKD2_k127_3466600_31 DinB superfamily - - - 0.0000000000000000000000000000004435 142.0
HKD2_k127_3466600_32 FtsX-like permease family - - - 0.000000000000000000000000000002942 139.0
HKD2_k127_3466600_33 protein conserved in bacteria - - - 0.0000000000000000000000000001558 122.0
HKD2_k127_3466600_34 Thioesterase K07107 - - 0.000000000000000000000000004965 126.0
HKD2_k127_3466600_35 Domain of unknown function DUF302 - - - 0.00000000000000000000000001652 118.0
HKD2_k127_3466600_36 thiolester hydrolase activity - - - 0.00000000000000000000000001943 125.0
HKD2_k127_3466600_37 Metal-sensitive transcriptional repressor - - - 0.0000000000000000000000003886 119.0
HKD2_k127_3466600_38 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000163 105.0
HKD2_k127_3466600_39 Forkhead associated domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.000000000000000000001131 100.0
HKD2_k127_3466600_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 466.0
HKD2_k127_3466600_40 Saccharopine dehydrogenase - - - 0.000000000000000000009208 106.0
HKD2_k127_3466600_41 - - - - 0.00000000000000000001003 106.0
HKD2_k127_3466600_42 pyridoxamine 5-phosphate K07005 - - 0.00000000000000000005605 99.0
HKD2_k127_3466600_43 Transmembrane domain of unknown function (DUF3566) - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000006889 74.0
HKD2_k127_3466600_44 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000001094 68.0
HKD2_k127_3466600_45 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000172 68.0
HKD2_k127_3466600_46 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000003458 77.0
HKD2_k127_3466600_47 - - - - 0.0000000007199 64.0
HKD2_k127_3466600_48 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.000000001683 65.0
HKD2_k127_3466600_5 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 437.0
HKD2_k127_3466600_50 Protein of unknown function (DUF721) - - - 0.0000001424 58.0
HKD2_k127_3466600_52 - - - - 0.000001624 58.0
HKD2_k127_3466600_53 histidine kinase A domain protein - - - 0.00008374 55.0
HKD2_k127_3466600_6 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 374.0
HKD2_k127_3466600_7 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 364.0
HKD2_k127_3466600_8 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 363.0
HKD2_k127_3466600_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 356.0
HKD2_k127_354557_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K12955 - - 0.0 1567.0
HKD2_k127_354557_1 PFAM Amidohydrolase 2 - - - 1.3e-204 661.0
HKD2_k127_354557_10 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 405.0
HKD2_k127_354557_11 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 371.0
HKD2_k127_354557_12 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 381.0
HKD2_k127_354557_13 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 353.0
HKD2_k127_354557_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 350.0
HKD2_k127_354557_15 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 351.0
HKD2_k127_354557_16 Regulator of polyketide synthase expression - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 352.0
HKD2_k127_354557_17 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 368.0
HKD2_k127_354557_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 348.0
HKD2_k127_354557_19 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 334.0
HKD2_k127_354557_2 FAD dependent oxidoreductase - - - 7.827e-203 650.0
HKD2_k127_354557_20 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 318.0
HKD2_k127_354557_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
HKD2_k127_354557_22 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
HKD2_k127_354557_23 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
HKD2_k127_354557_24 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 321.0
HKD2_k127_354557_25 Belongs to the MIP aquaporin (TC 1.A.8) family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000473 273.0
HKD2_k127_354557_26 cytochrome p450 K16046 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
HKD2_k127_354557_27 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000531 257.0
HKD2_k127_354557_28 capsule polysaccharide biosynthetic process K13687 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007574 286.0
HKD2_k127_354557_29 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001025 259.0
HKD2_k127_354557_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 617.0
HKD2_k127_354557_30 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000398 256.0
HKD2_k127_354557_31 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000008388 241.0
HKD2_k127_354557_32 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000001108 258.0
HKD2_k127_354557_33 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000001645 195.0
HKD2_k127_354557_34 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000136 176.0
HKD2_k127_354557_35 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000002703 171.0
HKD2_k127_354557_36 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000001123 173.0
HKD2_k127_354557_37 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.00000000000000000000000000000000000000007908 156.0
HKD2_k127_354557_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000003695 149.0
HKD2_k127_354557_39 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000002909 145.0
HKD2_k127_354557_4 cytochrome p450 K16046 - 1.14.13.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 541.0
HKD2_k127_354557_40 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000001053 146.0
HKD2_k127_354557_41 HNH endonuclease - - - 0.00000000000000000000000000000000006827 145.0
HKD2_k127_354557_42 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000001774 141.0
HKD2_k127_354557_43 Bacterial regulatory proteins, tetR family K22107 - - 0.0000000000000000000000000000000003931 147.0
HKD2_k127_354557_44 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000004545 139.0
HKD2_k127_354557_45 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000009732 138.0
HKD2_k127_354557_46 Amino acid permease K03294 - - 0.0000000000000000000000000001829 123.0
HKD2_k127_354557_47 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000003426 118.0
HKD2_k127_354557_48 Alpha/beta hydrolase family - - - 0.000000000000000000000000001946 122.0
HKD2_k127_354557_49 transcriptional regulator K03892 - - 0.000000000000000000000000006763 116.0
HKD2_k127_354557_5 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 484.0
HKD2_k127_354557_50 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000512 110.0
HKD2_k127_354557_51 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000002421 113.0
HKD2_k127_354557_52 - - - - 0.000000000000000000000003252 105.0
HKD2_k127_354557_53 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000004398 111.0
HKD2_k127_354557_54 Lipopolysaccharide assembly protein A domain - - - 0.00000000000000000003638 92.0
HKD2_k127_354557_55 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000002782 96.0
HKD2_k127_354557_56 GtrA-like protein - - - 0.0000000000000000003035 96.0
HKD2_k127_354557_57 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000007477 83.0
HKD2_k127_354557_58 - - - - 0.000000000000118 73.0
HKD2_k127_354557_6 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 455.0
HKD2_k127_354557_60 - - - - 0.0000000000002508 78.0
HKD2_k127_354557_61 Bacterial regulatory proteins, tetR family - - - 0.000000006276 66.0
HKD2_k127_354557_62 integral membrane protein - - - 0.00000003044 65.0
HKD2_k127_354557_63 Antibiotic biosynthesis monooxygenase - - - 0.0000001729 57.0
HKD2_k127_354557_64 - - - - 0.0000007142 59.0
HKD2_k127_354557_65 Protein of unknown function (DUF2510) - - - 0.0000007764 55.0
HKD2_k127_354557_66 META domain K03668 - - 0.000001831 61.0
HKD2_k127_354557_67 AAA ATPase domain - - - 0.00003487 52.0
HKD2_k127_354557_68 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000418 49.0
HKD2_k127_354557_69 lactoylglutathione lyase activity - - - 0.00004461 47.0
HKD2_k127_354557_7 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 458.0
HKD2_k127_354557_70 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03817 - - 0.0001233 46.0
HKD2_k127_354557_71 AAA ATPase domain - - - 0.0009135 49.0
HKD2_k127_354557_8 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 414.0
HKD2_k127_354557_9 Dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 403.0
HKD2_k127_3676205_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.911e-251 784.0
HKD2_k127_3676205_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.095e-195 628.0
HKD2_k127_3676205_10 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006817 286.0
HKD2_k127_3676205_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000229 273.0
HKD2_k127_3676205_12 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000003645 272.0
HKD2_k127_3676205_13 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000001639 251.0
HKD2_k127_3676205_14 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000003836 248.0
HKD2_k127_3676205_15 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000002337 235.0
HKD2_k127_3676205_16 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000004833 224.0
HKD2_k127_3676205_17 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000009162 211.0
HKD2_k127_3676205_18 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000453 201.0
HKD2_k127_3676205_19 cytochrome p450 - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - 0.000000000000000000000000000000000000000000000004571 189.0
HKD2_k127_3676205_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 501.0
HKD2_k127_3676205_20 zinc transporter K07238 - - 0.00000000000000000000000000000000000000000001518 170.0
HKD2_k127_3676205_21 - - - - 0.00000000000000000000000000000000000000000008877 168.0
HKD2_k127_3676205_22 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000003413 165.0
HKD2_k127_3676205_23 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000003444 127.0
HKD2_k127_3676205_24 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000006422 127.0
HKD2_k127_3676205_25 Transcriptional regulator PadR-like family - - - 0.0000000000000000000003629 100.0
HKD2_k127_3676205_26 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000357 98.0
HKD2_k127_3676205_27 Putative zinc-finger - - - 0.00000000001207 69.0
HKD2_k127_3676205_28 Phosphate acyltransferases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000001941 68.0
HKD2_k127_3676205_3 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 463.0
HKD2_k127_3676205_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 451.0
HKD2_k127_3676205_5 Pfam:Zinicin_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 343.0
HKD2_k127_3676205_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 322.0
HKD2_k127_3676205_7 Polyprenyl synthetase K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 303.0
HKD2_k127_3676205_8 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002003 289.0
HKD2_k127_3676205_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005738 278.0
HKD2_k127_3700977_0 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 492.0
HKD2_k127_3700977_1 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 429.0
HKD2_k127_3700977_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004143 253.0
HKD2_k127_3700977_11 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000001084 196.0
HKD2_k127_3700977_12 SnoaL-like domain K01822 - 5.3.3.1 0.00000000000000000000000000000000000000000000000001194 195.0
HKD2_k127_3700977_13 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000001125 145.0
HKD2_k127_3700977_14 Short C-terminal domain - - - 0.00000000000000000000000000000004053 128.0
HKD2_k127_3700977_15 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000008864 68.0
HKD2_k127_3700977_16 Involved in sulfation activity towards typical ceramide glycolipids and trehalose glycolipids K01014 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576 2.8.2.1 0.0000000005923 67.0
HKD2_k127_3700977_17 - - - - 0.00000005002 66.0
HKD2_k127_3700977_18 Homocysteine S-methyltransferase - - - 0.0000008834 50.0
HKD2_k127_3700977_19 Short repeat of unknown function (DUF308) - - - 0.0000009586 58.0
HKD2_k127_3700977_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
HKD2_k127_3700977_20 - - - - 0.0000691 53.0
HKD2_k127_3700977_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 376.0
HKD2_k127_3700977_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 379.0
HKD2_k127_3700977_5 Protein of unknown function (DUF1298) K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 330.0
HKD2_k127_3700977_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 313.0
HKD2_k127_3700977_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 316.0
HKD2_k127_3700977_8 Domain of unknown function (DUF1996) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003146 288.0
HKD2_k127_3700977_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
HKD2_k127_3744853_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32 3.863e-285 887.0
HKD2_k127_3744853_1 Fibronectin type III-like domain K05349 - 3.2.1.21 3.858e-206 667.0
HKD2_k127_3744853_10 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000002515 253.0
HKD2_k127_3744853_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000002843 212.0
HKD2_k127_3744853_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000002103 201.0
HKD2_k127_3744853_13 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000003548 194.0
HKD2_k127_3744853_14 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000000000003658 196.0
HKD2_k127_3744853_15 - K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000001224 171.0
HKD2_k127_3744853_16 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000001206 170.0
HKD2_k127_3744853_17 - - - - 0.0000000000000000000000000000000000000001668 161.0
HKD2_k127_3744853_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000001496 134.0
HKD2_k127_3744853_19 peptidase C60 sortase A and B - - - 0.00000000000000000000000000000003977 134.0
HKD2_k127_3744853_2 decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 518.0
HKD2_k127_3744853_20 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000001256 124.0
HKD2_k127_3744853_21 Anti-sigma-K factor rskA - - - 0.000000000000000000000000004004 123.0
HKD2_k127_3744853_22 AAA domain - - - 0.00000000000000000000000002316 117.0
HKD2_k127_3744853_23 AsnC family - - - 0.0000000000000000000000001182 113.0
HKD2_k127_3744853_24 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000007718 106.0
HKD2_k127_3744853_25 - - - - 0.000000000000000000000001447 107.0
HKD2_k127_3744853_26 Acyl-homoserine-lactone synthase - - - 0.000000000008333 79.0
HKD2_k127_3744853_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 484.0
HKD2_k127_3744853_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 444.0
HKD2_k127_3744853_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 417.0
HKD2_k127_3744853_6 DNA helicase K03657 GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 421.0
HKD2_k127_3744853_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 392.0
HKD2_k127_3744853_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 278.0
HKD2_k127_3744853_9 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003092 274.0
HKD2_k127_3885829_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.246e-269 850.0
HKD2_k127_3885829_1 Belongs to the thiolase family K00626 - 2.3.1.9 9.472e-199 624.0
HKD2_k127_3885829_10 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 401.0
HKD2_k127_3885829_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 397.0
HKD2_k127_3885829_12 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 269.0
HKD2_k127_3885829_13 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005869 255.0
HKD2_k127_3885829_14 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000000000000000000000000000000000000000000000009104 247.0
HKD2_k127_3885829_15 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 243.0
HKD2_k127_3885829_16 RNA polymerase K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000513 234.0
HKD2_k127_3885829_17 membrane - - - 0.00000000000000000000000000000000000000000000000000000002813 205.0
HKD2_k127_3885829_18 Abhydrolase family - - - 0.000000000000000000000000000000000000000000000000000001157 211.0
HKD2_k127_3885829_19 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000004299 204.0
HKD2_k127_3885829_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 623.0
HKD2_k127_3885829_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000001791 199.0
HKD2_k127_3885829_21 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000001551 195.0
HKD2_k127_3885829_22 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000009205 191.0
HKD2_k127_3885829_23 Cytochrome c - - - 0.00000000000000000000000000000000000000003545 161.0
HKD2_k127_3885829_24 ChaB - - - 0.000000000000000000000000000000000003531 141.0
HKD2_k127_3885829_25 endoribonuclease - - - 0.00000000000000000000000000000000001394 143.0
HKD2_k127_3885829_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000008978 136.0
HKD2_k127_3885829_27 Flavin reductase like domain - - - 0.000000000000000000000000000000001329 138.0
HKD2_k127_3885829_28 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000703 136.0
HKD2_k127_3885829_29 - - - - 0.00000000000000000000000000000001077 147.0
HKD2_k127_3885829_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 582.0
HKD2_k127_3885829_30 SnoaL-like domain - - - 0.000000000000000000000000000000412 135.0
HKD2_k127_3885829_31 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000007486 133.0
HKD2_k127_3885829_32 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000001045 121.0
HKD2_k127_3885829_33 - - - - 0.0000000000000000000000003967 115.0
HKD2_k127_3885829_34 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.00000000000000000000001788 106.0
HKD2_k127_3885829_35 PFAM Uncharacterised BCR, COG1649 K01179,K04618,K07346,K12685,K17734 - 1.1.3.9,3.2.1.4 0.0000000000000000000008889 111.0
HKD2_k127_3885829_36 negative regulation of transcription, DNA-templated - - - 0.00000000000000000004843 93.0
HKD2_k127_3885829_37 Domain of unknown function (DUF4383) - - - 0.000000000000000000107 95.0
HKD2_k127_3885829_38 Transmembrane secretion effector - - - 0.000000000000000002029 98.0
HKD2_k127_3885829_39 STAS domain K04749 - - 0.00000000004906 69.0
HKD2_k127_3885829_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 546.0
HKD2_k127_3885829_40 molybdenum cofactor guanylyltransferase activity K03752 - 2.7.7.77 0.0000000001093 74.0
HKD2_k127_3885829_41 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000002962 61.0
HKD2_k127_3885829_42 Universal stress protein family - - - 0.0000008791 58.0
HKD2_k127_3885829_43 Universal stress protein family - - - 0.00004455 53.0
HKD2_k127_3885829_5 CoA-transferase family III K07544 - 2.8.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 507.0
HKD2_k127_3885829_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 468.0
HKD2_k127_3885829_7 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 470.0
HKD2_k127_3885829_8 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 445.0
HKD2_k127_3885829_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 428.0
HKD2_k127_4032166_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.966e-272 863.0
HKD2_k127_4032166_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.21e-268 844.0
HKD2_k127_4032166_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 454.0
HKD2_k127_4032166_11 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 452.0
HKD2_k127_4032166_12 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 448.0
HKD2_k127_4032166_13 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 442.0
HKD2_k127_4032166_14 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 407.0
HKD2_k127_4032166_15 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 421.0
HKD2_k127_4032166_16 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
HKD2_k127_4032166_17 PFAM molybdopterin dehydrogenase, FAD-binding K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 357.0
HKD2_k127_4032166_18 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 345.0
HKD2_k127_4032166_19 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 330.0
HKD2_k127_4032166_2 General secretory system II, protein E domain protein K02652 - - 1.729e-228 720.0
HKD2_k127_4032166_20 Glycosyltransferase Family 4 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 331.0
HKD2_k127_4032166_21 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
HKD2_k127_4032166_22 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 327.0
HKD2_k127_4032166_23 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 307.0
HKD2_k127_4032166_24 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000006394 268.0
HKD2_k127_4032166_25 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002314 270.0
HKD2_k127_4032166_26 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005778 246.0
HKD2_k127_4032166_27 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000008734 228.0
HKD2_k127_4032166_28 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000268 217.0
HKD2_k127_4032166_29 carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000000000000000000000000000000000001737 225.0
HKD2_k127_4032166_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.265e-220 700.0
HKD2_k127_4032166_30 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000002949 228.0
HKD2_k127_4032166_31 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000003759 196.0
HKD2_k127_4032166_32 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000007168 189.0
HKD2_k127_4032166_33 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000002764 184.0
HKD2_k127_4032166_34 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000006935 173.0
HKD2_k127_4032166_35 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000007763 169.0
HKD2_k127_4032166_36 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000004496 179.0
HKD2_k127_4032166_37 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 - 1.1.1.328,2.7.7.76 0.000000000000000000000000000000000000003298 160.0
HKD2_k127_4032166_38 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.00000000000000000000000000000000608 137.0
HKD2_k127_4032166_39 - - - - 0.00000000000000000000000000000003042 142.0
HKD2_k127_4032166_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.197e-216 682.0
HKD2_k127_4032166_40 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000003211 112.0
HKD2_k127_4032166_41 Redoxin K03564 - 1.11.1.15 0.00000000000000000001844 94.0
HKD2_k127_4032166_42 Preprotein translocase subunit K03210 - - 0.00000000002262 70.0
HKD2_k127_4032166_43 Redoxin K03564 - 1.11.1.15 0.0000000005948 63.0
HKD2_k127_4032166_5 elongation factor Tu domain 2 protein K02355 - - 4.335e-200 643.0
HKD2_k127_4032166_6 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 496.0
HKD2_k127_4032166_7 Type II IV secretion system protein K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 490.0
HKD2_k127_4032166_8 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 479.0
HKD2_k127_4032166_9 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 469.0
HKD2_k127_4088076_0 Glutamate synthase K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2161.0
HKD2_k127_4088076_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.864e-284 895.0
HKD2_k127_4088076_10 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 543.0
HKD2_k127_4088076_11 D-arabinono-1,4-lactone oxidase K16653 - 1.1.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 527.0
HKD2_k127_4088076_12 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 507.0
HKD2_k127_4088076_13 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 496.0
HKD2_k127_4088076_14 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 486.0
HKD2_k127_4088076_15 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 487.0
HKD2_k127_4088076_16 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 461.0
HKD2_k127_4088076_17 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 456.0
HKD2_k127_4088076_18 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 459.0
HKD2_k127_4088076_19 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 440.0
HKD2_k127_4088076_2 ABC transporter K01995 - - 4.814e-245 821.0
HKD2_k127_4088076_20 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 436.0
HKD2_k127_4088076_21 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 434.0
HKD2_k127_4088076_22 Aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 424.0
HKD2_k127_4088076_23 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 430.0
HKD2_k127_4088076_24 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
HKD2_k127_4088076_25 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 387.0
HKD2_k127_4088076_26 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 400.0
HKD2_k127_4088076_27 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 377.0
HKD2_k127_4088076_28 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 356.0
HKD2_k127_4088076_29 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 355.0
HKD2_k127_4088076_3 N-acyl-D-aspartate D-glutamate deacylase - - - 5.669e-242 767.0
HKD2_k127_4088076_30 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 345.0
HKD2_k127_4088076_31 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 335.0
HKD2_k127_4088076_32 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 319.0
HKD2_k127_4088076_33 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 319.0
HKD2_k127_4088076_34 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 318.0
HKD2_k127_4088076_35 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000419 303.0
HKD2_k127_4088076_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 299.0
HKD2_k127_4088076_37 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K16652 - 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 286.0
HKD2_k127_4088076_38 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007709 271.0
HKD2_k127_4088076_39 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004859 266.0
HKD2_k127_4088076_4 glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.396e-240 751.0
HKD2_k127_4088076_40 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 263.0
HKD2_k127_4088076_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
HKD2_k127_4088076_42 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001453 259.0
HKD2_k127_4088076_43 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
HKD2_k127_4088076_44 UbiA prenyltransferase family K14136 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016763,GO:0031224,GO:0031226,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046872,GO:0052636,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000003531 257.0
HKD2_k127_4088076_45 Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006796 263.0
HKD2_k127_4088076_46 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000002292 235.0
HKD2_k127_4088076_47 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000005197 229.0
HKD2_k127_4088076_48 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000743 233.0
HKD2_k127_4088076_49 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000004043 231.0
HKD2_k127_4088076_5 PFAM AMP-dependent synthetase and ligase K18687 - 6.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 616.0
HKD2_k127_4088076_50 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000009614 222.0
HKD2_k127_4088076_51 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000006313 208.0
HKD2_k127_4088076_52 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.0000000000000000000000000000000000000000000000000000001905 201.0
HKD2_k127_4088076_53 acyl-CoA hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000002781 205.0
HKD2_k127_4088076_54 Replication protein - - - 0.00000000000000000000000000000000000000000000000000009996 193.0
HKD2_k127_4088076_55 haloacid dehalogenase-like hydrolase K18697 - 3.1.3.27 0.0000000000000000000000000000000000000000000003179 183.0
HKD2_k127_4088076_56 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000009471 168.0
HKD2_k127_4088076_57 acetyltransferase - - - 0.00000000000000000000000000000000000002761 158.0
HKD2_k127_4088076_58 Adenylyl- / guanylyl cyclase, catalytic domain K01768 GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000000000000000000000000004313 156.0
HKD2_k127_4088076_59 Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000001648 150.0
HKD2_k127_4088076_6 AMP-binding enzyme K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 567.0
HKD2_k127_4088076_60 transcriptional regulator K22107 - - 0.00000000000000000000000000000000004394 141.0
HKD2_k127_4088076_61 Oxidoreductase FAD-binding domain K00529,K02613 GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.18.1.3 0.000000000000000000000000000000002389 138.0
HKD2_k127_4088076_62 Nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000001925 128.0
HKD2_k127_4088076_63 ArsC family - - - 0.000000000000000000000000000003916 130.0
HKD2_k127_4088076_64 Transcriptional regulator - - - 0.0000000000000000000000000008635 120.0
HKD2_k127_4088076_65 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000005293 113.0
HKD2_k127_4088076_66 Rieske 2Fe-2S - - - 0.0000000000000000000002592 104.0
HKD2_k127_4088076_67 Domain of unknown function (DU1801) - - - 0.0000000000000000000008917 111.0
HKD2_k127_4088076_68 Secreted repeat of unknown function - - - 0.00000000000000000002413 100.0
HKD2_k127_4088076_69 - - - - 0.00000000000000006754 91.0
HKD2_k127_4088076_7 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 558.0
HKD2_k127_4088076_70 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.00000000000002013 88.0
HKD2_k127_4088076_71 - - - - 0.000000001453 69.0
HKD2_k127_4088076_72 Cytochrome D1 heme domain - - - 0.000000008622 64.0
HKD2_k127_4088076_73 - - - - 0.0001543 52.0
HKD2_k127_4088076_8 acyl-CoA dehydrogenase K00257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 552.0
HKD2_k127_4088076_9 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 554.0
HKD2_k127_4105072_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 1.406e-227 740.0
HKD2_k127_4105072_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 431.0
HKD2_k127_4105072_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 417.0
HKD2_k127_4105072_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 394.0
HKD2_k127_4105072_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 325.0
HKD2_k127_4105072_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000007533 142.0
HKD2_k127_4105072_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000005628 128.0
HKD2_k127_4105072_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000002175 126.0
HKD2_k127_4105072_8 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0007284 46.0
HKD2_k127_4128978_0 COG2015 Alkyl sulfatase and related hydrolases - - - 2.805e-282 887.0
HKD2_k127_4128978_1 transferase activity, transferring glycosyl groups - - - 1.147e-277 884.0
HKD2_k127_4128978_10 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 321.0
HKD2_k127_4128978_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000553 274.0
HKD2_k127_4128978_12 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005088 268.0
HKD2_k127_4128978_13 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004025 233.0
HKD2_k127_4128978_14 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000003065 227.0
HKD2_k127_4128978_15 - - - - 0.000000000000000000000000000000000000000000000000000000000007161 224.0
HKD2_k127_4128978_16 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000008592 211.0
HKD2_k127_4128978_17 Formamidopyrimidine-DNA glycosylase H2TH domain K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000001624 209.0
HKD2_k127_4128978_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000239 174.0
HKD2_k127_4128978_19 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000001684 146.0
HKD2_k127_4128978_2 PFAM Major Facilitator Superfamily - - - 6.955e-194 635.0
HKD2_k127_4128978_20 - - - - 0.000000000000000000000000000002069 136.0
HKD2_k127_4128978_21 - - - - 0.000000000000000000000000000002619 125.0
HKD2_k127_4128978_22 Ion channel - - - 0.000000000000000000000000844 113.0
HKD2_k127_4128978_23 RDD family - - - 0.00000000000000000003389 106.0
HKD2_k127_4128978_24 Virulence factor BrkB - - - 0.000000000000003142 87.0
HKD2_k127_4128978_25 - - - - 0.000000009096 65.0
HKD2_k127_4128978_26 Sap, sulfolipid-1-addressing protein - - - 0.00000003374 64.0
HKD2_k127_4128978_27 Endonuclease/Exonuclease/phosphatase family K18353 - - 0.00000003551 65.0
HKD2_k127_4128978_28 Xylose isomerase-like TIM barrel - - - 0.00000386 51.0
HKD2_k127_4128978_3 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 449.0
HKD2_k127_4128978_4 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 418.0
HKD2_k127_4128978_5 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 411.0
HKD2_k127_4128978_6 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 372.0
HKD2_k127_4128978_7 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 364.0
HKD2_k127_4128978_8 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 345.0
HKD2_k127_4128978_9 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 341.0
HKD2_k127_4138106_0 B12 binding domain K00548 - 2.1.1.13 0.0 1478.0
HKD2_k127_4138106_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.705e-246 777.0
HKD2_k127_4138106_10 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 521.0
HKD2_k127_4138106_11 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 488.0
HKD2_k127_4138106_12 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K18912 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 501.0
HKD2_k127_4138106_13 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 479.0
HKD2_k127_4138106_14 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 470.0
HKD2_k127_4138106_15 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 443.0
HKD2_k127_4138106_16 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008213,GO:0008276,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0019439,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0036211,GO:0042398,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052707,GO:0052708,GO:0052709,GO:0052803,GO:0052805,GO:0071704,GO:0071944,GO:0097164,GO:0140096,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 423.0
HKD2_k127_4138106_17 Flp pilus assembly protein ATPase CpaF K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 414.0
HKD2_k127_4138106_18 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 387.0
HKD2_k127_4138106_19 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 368.0
HKD2_k127_4138106_2 Uncharacterized protein family (UPF0051) K09014 - - 3.855e-236 745.0
HKD2_k127_4138106_20 ubiquinone biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 363.0
HKD2_k127_4138106_21 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 344.0
HKD2_k127_4138106_22 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 355.0
HKD2_k127_4138106_23 tRNA methyl transferase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 342.0
HKD2_k127_4138106_24 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
HKD2_k127_4138106_25 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 326.0
HKD2_k127_4138106_26 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 294.0
HKD2_k127_4138106_27 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 285.0
HKD2_k127_4138106_28 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD2_k127_4138106_29 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003245 285.0
HKD2_k127_4138106_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 7.905e-229 750.0
HKD2_k127_4138106_30 response regulator, receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008493 273.0
HKD2_k127_4138106_31 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001751 278.0
HKD2_k127_4138106_32 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001064 288.0
HKD2_k127_4138106_33 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003727 272.0
HKD2_k127_4138106_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 274.0
HKD2_k127_4138106_35 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008365 273.0
HKD2_k127_4138106_36 Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000009318 268.0
HKD2_k127_4138106_37 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001997 270.0
HKD2_k127_4138106_38 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
HKD2_k127_4138106_39 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000003737 256.0
HKD2_k127_4138106_4 Uncharacterised protein family (UPF0182) K09118 - - 1.317e-221 720.0
HKD2_k127_4138106_40 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000004674 213.0
HKD2_k127_4138106_41 PFAM Type II secretion system F domain K12510 - - 0.000000000000000000000000000000000000000000000000000000000002841 226.0
HKD2_k127_4138106_42 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001452 218.0
HKD2_k127_4138106_43 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000000000000000000000000000000000000000000000001391 211.0
HKD2_k127_4138106_44 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000001691 215.0
HKD2_k127_4138106_45 Major facilitator Superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000008631 214.0
HKD2_k127_4138106_46 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.000000000000000000000000000000000000000000000000001796 205.0
HKD2_k127_4138106_47 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000001485 186.0
HKD2_k127_4138106_48 Pfam:Zinicin_2 - - - 0.00000000000000000000000000000000000000000000000007027 194.0
HKD2_k127_4138106_49 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000001272 188.0
HKD2_k127_4138106_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 9.466e-211 674.0
HKD2_k127_4138106_50 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000003334 196.0
HKD2_k127_4138106_51 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000006114 197.0
HKD2_k127_4138106_52 Type ii secretion system K12511 - - 0.000000000000000000000000000000000000000000000001159 186.0
HKD2_k127_4138106_53 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000002623 185.0
HKD2_k127_4138106_54 - - - - 0.0000000000000000000000000000000000000000000005053 186.0
HKD2_k127_4138106_55 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000002485 172.0
HKD2_k127_4138106_56 Domain present in PSD-95, Dlg, and ZO-1/2. K07177 - - 0.0000000000000000000000000000000000000000009503 171.0
HKD2_k127_4138106_57 MaoC like domain - - - 0.000000000000000000000000000000000000000001394 165.0
HKD2_k127_4138106_58 Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K07008 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368 3.5.1.118 0.000000000000000000000000000000000000000006102 173.0
HKD2_k127_4138106_59 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000008557 155.0
HKD2_k127_4138106_6 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 544.0
HKD2_k127_4138106_60 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000001883 159.0
HKD2_k127_4138106_61 Domain of unknown function (DUF1802) - - - 0.00000000000000000000000000000000000003479 156.0
HKD2_k127_4138106_62 Epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000008627 161.0
HKD2_k127_4138106_63 - - - - 0.00000000000000000000000000000000004596 142.0
HKD2_k127_4138106_64 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000252 142.0
HKD2_k127_4138106_65 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000005669 138.0
HKD2_k127_4138106_66 regulation of cell shape K04074 - - 0.00000000000000000000000000000005404 144.0
HKD2_k127_4138106_67 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000001431 127.0
HKD2_k127_4138106_68 Rieske 2Fe-2S domain K05710 - - 0.00000000000000000000000001813 111.0
HKD2_k127_4138106_69 Sterol carrier protein - - - 0.0000000000000000000000006693 111.0
HKD2_k127_4138106_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 527.0
HKD2_k127_4138106_70 - - - - 0.0000000000000000000001524 108.0
HKD2_k127_4138106_71 - - - - 0.00000000000000000001352 104.0
HKD2_k127_4138106_72 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000008809 102.0
HKD2_k127_4138106_73 Ferredoxin K05337 - - 0.0000000000000000005004 89.0
HKD2_k127_4138106_74 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000005181 95.0
HKD2_k127_4138106_76 LysM domain - - - 0.000000000001705 78.0
HKD2_k127_4138106_77 Helix-turn-helix domain - - - 0.00000001446 66.0
HKD2_k127_4138106_78 - - - - 0.00002588 55.0
HKD2_k127_4138106_79 - - - - 0.00006038 51.0
HKD2_k127_4138106_8 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 527.0
HKD2_k127_4138106_80 TadE-like protein - - - 0.00008218 50.0
HKD2_k127_4138106_81 - - - - 0.00008771 53.0
HKD2_k127_4138106_82 Pilus assembly protein CpaB K02279 - - 0.0003048 51.0
HKD2_k127_4138106_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 533.0
HKD2_k127_4196174_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 3.738e-313 983.0
HKD2_k127_4196174_1 von Willebrand factor (vWF) type A domain - - - 2.208e-242 766.0
HKD2_k127_4196174_10 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 323.0
HKD2_k127_4196174_11 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 311.0
HKD2_k127_4196174_12 Phosphate transport system permease K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 289.0
HKD2_k127_4196174_13 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007697 267.0
HKD2_k127_4196174_14 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000005207 231.0
HKD2_k127_4196174_15 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000001447 235.0
HKD2_k127_4196174_16 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000003603 195.0
HKD2_k127_4196174_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000001437 195.0
HKD2_k127_4196174_18 RNA polymerase sigma factor, sigma-70 family K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000003401 174.0
HKD2_k127_4196174_19 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000003844 161.0
HKD2_k127_4196174_2 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 4.707e-211 671.0
HKD2_k127_4196174_20 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000306 159.0
HKD2_k127_4196174_21 Major facilitator superfamily - - - 0.0000000000000000000000000000000000003485 158.0
HKD2_k127_4196174_23 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000001718 149.0
HKD2_k127_4196174_24 isomerase activity - - - 0.00000000000000000000000000000000003566 154.0
HKD2_k127_4196174_25 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000001001 136.0
HKD2_k127_4196174_27 - - - - 0.00000000000000000000000000000004727 138.0
HKD2_k127_4196174_28 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000002071 114.0
HKD2_k127_4196174_29 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000084 114.0
HKD2_k127_4196174_3 Cystathionine beta-synthase K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 547.0
HKD2_k127_4196174_30 lactoylglutathione lyase activity - - - 0.0000000000000000000000001282 111.0
HKD2_k127_4196174_31 - - - - 0.0000000000000000000000001689 115.0
HKD2_k127_4196174_32 response regulator K07668,K07775 - - 0.000000000000000000000003423 109.0
HKD2_k127_4196174_34 SnoaL-like domain - - - 0.0000000000000000000007511 105.0
HKD2_k127_4196174_36 antisigma factor binding K03598 - - 0.000000004145 68.0
HKD2_k127_4196174_37 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00001374 58.0
HKD2_k127_4196174_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 510.0
HKD2_k127_4196174_5 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 517.0
HKD2_k127_4196174_6 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 409.0
HKD2_k127_4196174_7 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 368.0
HKD2_k127_4196174_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 381.0
HKD2_k127_4196174_9 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 340.0
HKD2_k127_4363975_0 Pfam Amidohydrolase - - - 5.473e-237 738.0
HKD2_k127_4363975_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 612.0
HKD2_k127_4363975_10 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 496.0
HKD2_k127_4363975_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 511.0
HKD2_k127_4363975_12 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 497.0
HKD2_k127_4363975_13 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 442.0
HKD2_k127_4363975_14 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 418.0
HKD2_k127_4363975_15 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 379.0
HKD2_k127_4363975_16 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 386.0
HKD2_k127_4363975_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 371.0
HKD2_k127_4363975_18 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
HKD2_k127_4363975_19 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 385.0
HKD2_k127_4363975_2 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 601.0
HKD2_k127_4363975_20 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 348.0
HKD2_k127_4363975_21 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 334.0
HKD2_k127_4363975_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 334.0
HKD2_k127_4363975_23 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 339.0
HKD2_k127_4363975_24 Phosphoglycerate mutase family K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 332.0
HKD2_k127_4363975_25 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 319.0
HKD2_k127_4363975_26 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 296.0
HKD2_k127_4363975_27 AMP-binding enzyme C-terminal domain K01897,K12508 - 6.2.1.3,6.2.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001261 292.0
HKD2_k127_4363975_28 capsule polysaccharide biosynthetic process K13687 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001953 294.0
HKD2_k127_4363975_29 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001262 257.0
HKD2_k127_4363975_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 596.0
HKD2_k127_4363975_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
HKD2_k127_4363975_31 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005376 247.0
HKD2_k127_4363975_32 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003804 245.0
HKD2_k127_4363975_33 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004501 241.0
HKD2_k127_4363975_34 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001047 249.0
HKD2_k127_4363975_35 Enoyl-(Acyl carrier protein) reductase K19811 - 1.1.1.357 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
HKD2_k127_4363975_36 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000000000000207 197.0
HKD2_k127_4363975_37 KR domain - - - 0.00000000000000000000000000000000000000000000000000001498 212.0
HKD2_k127_4363975_38 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000005241 197.0
HKD2_k127_4363975_39 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000245 205.0
HKD2_k127_4363975_4 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity K08080,K14952 - 1.14.18.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 586.0
HKD2_k127_4363975_40 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001516 196.0
HKD2_k127_4363975_41 peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000008251 193.0
HKD2_k127_4363975_42 Bax inhibitor 1 like - - - 0.0000000000000000000000000000000000000000000001025 195.0
HKD2_k127_4363975_43 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000003533 176.0
HKD2_k127_4363975_44 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000001193 168.0
HKD2_k127_4363975_45 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000003758 155.0
HKD2_k127_4363975_46 Methyltransferase domain - - - 0.000000000000000000000000000000000003681 146.0
HKD2_k127_4363975_47 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.000000000000000000000000000000001266 130.0
HKD2_k127_4363975_48 transcriptional regulator - - - 0.000000000000000000000000000003324 133.0
HKD2_k127_4363975_49 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000004182 133.0
HKD2_k127_4363975_5 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00146 - 1.2.1.3,1.2.1.39,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 575.0
HKD2_k127_4363975_50 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000003094 126.0
HKD2_k127_4363975_51 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000005352 123.0
HKD2_k127_4363975_52 N-terminal half of MaoC dehydratase - - - 0.0000000000000000004468 92.0
HKD2_k127_4363975_53 PHP domain - - - 0.0000000000000000006915 96.0
HKD2_k127_4363975_54 Transmembrane protein 260 - - - 0.000000001417 71.0
HKD2_k127_4363975_6 AMP-binding enzyme K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 578.0
HKD2_k127_4363975_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 562.0
HKD2_k127_4363975_8 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 537.0
HKD2_k127_4363975_9 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 533.0
HKD2_k127_4579078_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 592.0
HKD2_k127_4579078_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000002363 224.0
HKD2_k127_4579078_2 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000006179 220.0
HKD2_k127_4579078_3 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000003128 155.0
HKD2_k127_4579078_4 Transcriptional regulator - - - 0.000000000000000000000000000048 128.0
HKD2_k127_4614566_0 Ftsk_gamma K03466 - - 3.526e-200 663.0
HKD2_k127_4614566_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 5.773e-196 625.0
HKD2_k127_4614566_10 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 371.0
HKD2_k127_4614566_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 379.0
HKD2_k127_4614566_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 360.0
HKD2_k127_4614566_13 Peptidase family M28 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 341.0
HKD2_k127_4614566_14 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007785 276.0
HKD2_k127_4614566_15 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000001072 264.0
HKD2_k127_4614566_16 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000003586 251.0
HKD2_k127_4614566_17 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000001775 254.0
HKD2_k127_4614566_18 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0008150,GO:0040007 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000117 232.0
HKD2_k127_4614566_19 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.00000000000000000000000000000000000000000000000000000000006853 220.0
HKD2_k127_4614566_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 552.0
HKD2_k127_4614566_20 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000668 208.0
HKD2_k127_4614566_21 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000001436 194.0
HKD2_k127_4614566_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000009682 191.0
HKD2_k127_4614566_23 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000002551 191.0
HKD2_k127_4614566_24 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000002828 154.0
HKD2_k127_4614566_25 membrane transporter protein K07090 - - 0.000000000000000000000000000000000005424 159.0
HKD2_k127_4614566_26 sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000006431 143.0
HKD2_k127_4614566_27 GAF domain - - - 0.000000000000000000000000000000000009075 155.0
HKD2_k127_4614566_28 Chromate transporter K07240 - - 0.000000000000000000000000000000006376 130.0
HKD2_k127_4614566_29 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000002952 131.0
HKD2_k127_4614566_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 466.0
HKD2_k127_4614566_30 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007892 131.0
HKD2_k127_4614566_31 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000001641 120.0
HKD2_k127_4614566_32 helix_turn_helix, mercury resistance - - - 0.000000000000000000000856 105.0
HKD2_k127_4614566_33 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000003116 91.0
HKD2_k127_4614566_34 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000001108 78.0
HKD2_k127_4614566_35 - - - - 0.00000007755 59.0
HKD2_k127_4614566_36 Lysin motif - - - 0.00000108 58.0
HKD2_k127_4614566_37 - - - - 0.000002676 58.0
HKD2_k127_4614566_4 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 452.0
HKD2_k127_4614566_5 Enoyl-CoA hydratase/isomerase K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 422.0
HKD2_k127_4614566_6 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 416.0
HKD2_k127_4614566_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 415.0
HKD2_k127_4614566_8 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 408.0
HKD2_k127_4614566_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 383.0
HKD2_k127_476588_0 Flavin containing amine oxidoreductase - - - 6.895e-216 696.0
HKD2_k127_476588_1 PFAM Copper amine oxidase K00276 - 1.4.3.21 3.947e-212 685.0
HKD2_k127_476588_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 363.0
HKD2_k127_476588_11 KR domain K00059 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 363.0
HKD2_k127_476588_12 Belongs to the MenA family. Type 1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 356.0
HKD2_k127_476588_13 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 362.0
HKD2_k127_476588_14 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 330.0
HKD2_k127_476588_15 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 319.0
HKD2_k127_476588_16 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 302.0
HKD2_k127_476588_17 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
HKD2_k127_476588_18 Monogalactosyldiacylglycerol (MGDG) synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001291 276.0
HKD2_k127_476588_19 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 255.0
HKD2_k127_476588_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 586.0
HKD2_k127_476588_20 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004585 276.0
HKD2_k127_476588_21 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 254.0
HKD2_k127_476588_22 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001059 256.0
HKD2_k127_476588_23 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000001611 239.0
HKD2_k127_476588_24 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000323 233.0
HKD2_k127_476588_25 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000004606 195.0
HKD2_k127_476588_26 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000009621 196.0
HKD2_k127_476588_27 cAMP biosynthetic process K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000002304 191.0
HKD2_k127_476588_28 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000001553 177.0
HKD2_k127_476588_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000002135 162.0
HKD2_k127_476588_3 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 580.0
HKD2_k127_476588_30 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000001654 158.0
HKD2_k127_476588_31 Glycosyltransferase family 28 C-terminal domain K16039 - - 0.0000000000000000000000000000000000000002018 165.0
HKD2_k127_476588_32 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000002423 162.0
HKD2_k127_476588_33 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000005699 158.0
HKD2_k127_476588_34 YhhN family - - - 0.000000000000000000000000000000005856 136.0
HKD2_k127_476588_35 Lipocalin-like domain - - - 0.00000000000000000000000000003846 121.0
HKD2_k127_476588_36 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000008909 126.0
HKD2_k127_476588_37 arsR family - - - 0.000000000000000000000000001257 115.0
HKD2_k127_476588_38 - - - - 0.000000000000000000000000009676 115.0
HKD2_k127_476588_39 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000002965 117.0
HKD2_k127_476588_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 527.0
HKD2_k127_476588_40 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.0000000000000000000000009535 113.0
HKD2_k127_476588_41 FMN binding - - - 0.0000000000000000000000132 116.0
HKD2_k127_476588_42 Belongs to the 'phage' integrase family - - - 0.00000000000000000000005038 109.0
HKD2_k127_476588_43 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000001664 103.0
HKD2_k127_476588_44 Transcriptional regulator - - - 0.000000000000000003401 97.0
HKD2_k127_476588_45 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000007428 84.0
HKD2_k127_476588_46 - - - - 0.0000000000000105 81.0
HKD2_k127_476588_5 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 511.0
HKD2_k127_476588_6 CoA-transferase family III K07749,K18313 - 2.8.3.16,2.8.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 479.0
HKD2_k127_476588_7 PFAM Conserved region in glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 451.0
HKD2_k127_476588_8 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 432.0
HKD2_k127_476588_9 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 380.0
HKD2_k127_4840949_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.8 2.713e-304 953.0
HKD2_k127_4840949_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.174e-246 788.0
HKD2_k127_4840949_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 327.0
HKD2_k127_4840949_11 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
HKD2_k127_4840949_12 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 312.0
HKD2_k127_4840949_13 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
HKD2_k127_4840949_14 DHH family K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 292.0
HKD2_k127_4840949_15 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000002296 237.0
HKD2_k127_4840949_16 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000358 226.0
HKD2_k127_4840949_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000001073 186.0
HKD2_k127_4840949_18 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000006385 185.0
HKD2_k127_4840949_19 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000002376 166.0
HKD2_k127_4840949_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 556.0
HKD2_k127_4840949_20 Pfam:DUF385 - - - 0.000000000000000000000000000000000000000004598 159.0
HKD2_k127_4840949_21 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000003322 171.0
HKD2_k127_4840949_22 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000003863 143.0
HKD2_k127_4840949_23 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000542 128.0
HKD2_k127_4840949_25 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000006145 98.0
HKD2_k127_4840949_26 protein conserved in bacteria K09764 - - 0.00000000000000000006211 95.0
HKD2_k127_4840949_27 Fatty acid desaturase - - - 0.000000000000000006877 98.0
HKD2_k127_4840949_28 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000003846 90.0
HKD2_k127_4840949_29 Protein of unknown function (DUF448) K07742 - - 0.000000005646 64.0
HKD2_k127_4840949_3 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 522.0
HKD2_k127_4840949_30 Pentapeptide repeats (9 copies) - - - 0.00000002877 61.0
HKD2_k127_4840949_4 Participates in both transcription termination and antitermination K02600 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 488.0
HKD2_k127_4840949_5 DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 461.0
HKD2_k127_4840949_6 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 440.0
HKD2_k127_4840949_7 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 407.0
HKD2_k127_4840949_8 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 379.0
HKD2_k127_4840949_9 3-demethylubiquinone-9 3-O-methyltransferase activity K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 349.0
HKD2_k127_4925065_0 ATP-dependent Clp protease K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1253.0
HKD2_k127_4925065_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 432.0
HKD2_k127_4925065_10 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000936 174.0
HKD2_k127_4925065_11 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000006685 165.0
HKD2_k127_4925065_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000005592 151.0
HKD2_k127_4925065_13 Polyprenyl synthetase K00805 - 2.5.1.30 0.000000000000000000000000000000000000006759 169.0
HKD2_k127_4925065_15 - - - - 0.000321 51.0
HKD2_k127_4925065_2 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 390.0
HKD2_k127_4925065_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 355.0
HKD2_k127_4925065_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 309.0
HKD2_k127_4925065_5 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000003665 244.0
HKD2_k127_4925065_6 helix_turn_helix, cAMP Regulatory protein K01420,K10914,K21561,K21564 - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
HKD2_k127_4925065_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000001922 212.0
HKD2_k127_4925065_8 nuclease activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000005841 197.0
HKD2_k127_4925065_9 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000001129 198.0
HKD2_k127_4980774_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 527.0
HKD2_k127_4980774_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 407.0
HKD2_k127_4980774_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000002511 99.0
HKD2_k127_4980774_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000001108 75.0
HKD2_k127_4980774_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 336.0
HKD2_k127_4980774_3 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002087 268.0
HKD2_k127_4980774_4 ATPases associated with a variety of cellular activities K01990,K09691,K09693 - 3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000003381 243.0
HKD2_k127_4980774_5 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000003768 235.0
HKD2_k127_4980774_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000772 205.0
HKD2_k127_4980774_7 transferase activity, transferring glycosyl groups K12994,K21002 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000487 192.0
HKD2_k127_4980774_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000002068 188.0
HKD2_k127_4980774_9 ATPase MipZ - - - 0.0000000000000000000000000000001885 139.0
HKD2_k127_5057261_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 404.0
HKD2_k127_5057261_1 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 364.0
HKD2_k127_5057261_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000003125 73.0
HKD2_k127_5057261_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
HKD2_k127_5057261_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 265.0
HKD2_k127_5057261_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001969 228.0
HKD2_k127_5057261_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
HKD2_k127_5057261_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001969 195.0
HKD2_k127_5057261_7 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000000000001312 164.0
HKD2_k127_5057261_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000008232 138.0
HKD2_k127_5057261_9 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000007921 74.0
HKD2_k127_5136978_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1114.0
HKD2_k127_5136978_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 6.962e-261 827.0
HKD2_k127_5136978_10 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 580.0
HKD2_k127_5136978_100 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000003358 179.0
HKD2_k127_5136978_101 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000004034 171.0
HKD2_k127_5136978_102 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000003774 164.0
HKD2_k127_5136978_103 Nitroreductase family - - - 0.000000000000000000000000000000000000000004348 165.0
HKD2_k127_5136978_104 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000007752 160.0
HKD2_k127_5136978_105 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000008782 161.0
HKD2_k127_5136978_106 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 - 2.7.8.24 0.000000000000000000000000000000000000000008865 175.0
HKD2_k127_5136978_107 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000006542 156.0
HKD2_k127_5136978_108 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000003211 160.0
HKD2_k127_5136978_109 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000006402 148.0
HKD2_k127_5136978_11 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016651,GO:0016655,GO:0036094,GO:0043167,GO:0043168,GO:0044419,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0051704,GO:0055114,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 583.0
HKD2_k127_5136978_110 Peptidase M23 K21471 - - 0.00000000000000000000000000000000000001399 159.0
HKD2_k127_5136978_112 Beta-lactamase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000008794 156.0
HKD2_k127_5136978_113 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000317 141.0
HKD2_k127_5136978_114 Ring hydroxylating beta subunit - - - 0.0000000000000000000000000000000008191 148.0
HKD2_k127_5136978_115 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000004734 148.0
HKD2_k127_5136978_116 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000002383 133.0
HKD2_k127_5136978_117 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00000000000000000000000000000007581 130.0
HKD2_k127_5136978_119 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA K08299 - 4.2.1.149 0.00000000000000000000000000001582 129.0
HKD2_k127_5136978_12 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 555.0
HKD2_k127_5136978_120 thiolester hydrolase activity K01186 - 3.2.1.18 0.00000000000000000000000000005432 129.0
HKD2_k127_5136978_121 YCII-related domain K09780 - - 0.0000000000000000000000000002708 120.0
HKD2_k127_5136978_122 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000191 116.0
HKD2_k127_5136978_123 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000003845 112.0
HKD2_k127_5136978_124 - - - - 0.00000000000000000000000003693 111.0
HKD2_k127_5136978_125 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000006747 108.0
HKD2_k127_5136978_126 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000117 109.0
HKD2_k127_5136978_127 COGs COG0694 Thioredoxin-like protein and domains - - - 0.000000000000000000000002377 104.0
HKD2_k127_5136978_128 competence protein K03654 - 3.6.4.12 0.000000000000000000000004253 119.0
HKD2_k127_5136978_129 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000004617 107.0
HKD2_k127_5136978_13 Belongs to the DegT DnrJ EryC1 family K12452,K13328 - 1.17.1.1,4.2.1.164 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 530.0
HKD2_k127_5136978_130 Protein of unknown function (DUF3039) - - - 0.0000000000000000000003764 99.0
HKD2_k127_5136978_131 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000004006 101.0
HKD2_k127_5136978_132 Protein of unknown function (DUF4239) - - - 0.000000000000000005505 94.0
HKD2_k127_5136978_133 peptidase inhibitor activity - - - 0.000000000000000006149 97.0
HKD2_k127_5136978_134 Thioesterase superfamily - - - 0.0000000001438 72.0
HKD2_k127_5136978_135 Thioesterase superfamily - - - 0.00000000276 69.0
HKD2_k127_5136978_136 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.000000003263 70.0
HKD2_k127_5136978_137 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000003856 59.0
HKD2_k127_5136978_138 SnoaL-like domain - - - 0.00000004329 65.0
HKD2_k127_5136978_139 - - - - 0.0000002084 64.0
HKD2_k127_5136978_14 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 504.0
HKD2_k127_5136978_141 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000004035 51.0
HKD2_k127_5136978_143 POZ domain binding K10454 GO:0000151,GO:0003674,GO:0003779,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006996,GO:0007010,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008092,GO:0008150,GO:0009987,GO:0014069,GO:0015629,GO:0016043,GO:0019904,GO:0030029,GO:0030036,GO:0030425,GO:0031208,GO:0031461,GO:0031463,GO:0032279,GO:0032501,GO:0032502,GO:0032838,GO:0032839,GO:0032947,GO:0032991,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044297,GO:0044424,GO:0044444,GO:0044456,GO:0044463,GO:0044464,GO:0044877,GO:0045202,GO:0048513,GO:0048731,GO:0048856,GO:0051015,GO:0060322,GO:0071840,GO:0097447,GO:0097458,GO:0098794,GO:0098984,GO:0099568,GO:0099572,GO:0120025,GO:0120038,GO:0120111,GO:1902494,GO:1990234 - 0.0001008 54.0
HKD2_k127_5136978_144 EthD domain - - - 0.0004656 52.0
HKD2_k127_5136978_145 - - - - 0.0009684 46.0
HKD2_k127_5136978_15 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 508.0
HKD2_k127_5136978_16 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 501.0
HKD2_k127_5136978_17 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 475.0
HKD2_k127_5136978_18 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 458.0
HKD2_k127_5136978_19 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 454.0
HKD2_k127_5136978_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.312e-249 792.0
HKD2_k127_5136978_20 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 477.0
HKD2_k127_5136978_21 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 438.0
HKD2_k127_5136978_22 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 447.0
HKD2_k127_5136978_23 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 436.0
HKD2_k127_5136978_24 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 441.0
HKD2_k127_5136978_25 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 431.0
HKD2_k127_5136978_26 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 434.0
HKD2_k127_5136978_27 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 423.0
HKD2_k127_5136978_28 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0008150,GO:0040007 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 428.0
HKD2_k127_5136978_29 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 402.0
HKD2_k127_5136978_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.058e-239 748.0
HKD2_k127_5136978_30 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 394.0
HKD2_k127_5136978_31 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
HKD2_k127_5136978_32 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 390.0
HKD2_k127_5136978_33 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 406.0
HKD2_k127_5136978_34 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 387.0
HKD2_k127_5136978_35 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HKD2_k127_5136978_36 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 377.0
HKD2_k127_5136978_37 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007933 390.0
HKD2_k127_5136978_38 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 390.0
HKD2_k127_5136978_39 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 353.0
HKD2_k127_5136978_4 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.414e-239 749.0
HKD2_k127_5136978_40 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 384.0
HKD2_k127_5136978_41 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 356.0
HKD2_k127_5136978_42 ATPases associated with a variety of cellular activities K09812 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 347.0
HKD2_k127_5136978_43 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 346.0
HKD2_k127_5136978_44 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 341.0
HKD2_k127_5136978_45 NADP-dependent oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 338.0
HKD2_k127_5136978_46 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 324.0
HKD2_k127_5136978_47 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 325.0
HKD2_k127_5136978_48 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 324.0
HKD2_k127_5136978_49 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 316.0
HKD2_k127_5136978_5 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 8.2e-233 736.0
HKD2_k127_5136978_50 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 320.0
HKD2_k127_5136978_51 epimerase dehydratase K01710,K01784 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 319.0
HKD2_k127_5136978_52 SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 305.0
HKD2_k127_5136978_53 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 306.0
HKD2_k127_5136978_54 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 298.0
HKD2_k127_5136978_55 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 308.0
HKD2_k127_5136978_56 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 327.0
HKD2_k127_5136978_57 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 292.0
HKD2_k127_5136978_58 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 296.0
HKD2_k127_5136978_59 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 308.0
HKD2_k127_5136978_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.403e-228 724.0
HKD2_k127_5136978_60 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000178 290.0
HKD2_k127_5136978_61 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 293.0
HKD2_k127_5136978_62 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 288.0
HKD2_k127_5136978_63 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001142 285.0
HKD2_k127_5136978_64 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
HKD2_k127_5136978_65 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000421 278.0
HKD2_k127_5136978_66 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000025 279.0
HKD2_k127_5136978_67 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000921 281.0
HKD2_k127_5136978_68 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001373 276.0
HKD2_k127_5136978_69 Bacterial phospho-glucose isomerase C-terminal SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
HKD2_k127_5136978_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 2.874e-209 661.0
HKD2_k127_5136978_70 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007435 263.0
HKD2_k127_5136978_71 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003508 268.0
HKD2_k127_5136978_72 PFAM chorismate K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000006131 267.0
HKD2_k127_5136978_73 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002382 272.0
HKD2_k127_5136978_74 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001162 273.0
HKD2_k127_5136978_75 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000326 251.0
HKD2_k127_5136978_76 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000004536 251.0
HKD2_k127_5136978_77 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008162 257.0
HKD2_k127_5136978_78 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000009716 246.0
HKD2_k127_5136978_79 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000007025 253.0
HKD2_k127_5136978_8 Circularly permuted ATP-grasp type 2 K06048 - - 1.823e-207 661.0
HKD2_k127_5136978_80 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002108 255.0
HKD2_k127_5136978_81 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007744 252.0
HKD2_k127_5136978_83 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001792 228.0
HKD2_k127_5136978_84 Major Facilitator Superfamily K03535 - - 0.00000000000000000000000000000000000000000000000000000000000002044 239.0
HKD2_k127_5136978_85 LURP-one-related - - - 0.00000000000000000000000000000000000000000000000000000000002242 218.0
HKD2_k127_5136978_86 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000001405 207.0
HKD2_k127_5136978_87 hydrolase K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000008861 203.0
HKD2_k127_5136978_88 - - - - 0.000000000000000000000000000000000000000000000000000007244 196.0
HKD2_k127_5136978_89 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001607 202.0
HKD2_k127_5136978_9 Belongs to the group II decarboxylase family K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 621.0
HKD2_k127_5136978_90 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000007867 207.0
HKD2_k127_5136978_91 Enoyl-CoA hydratase/isomerase K01692,K15866 - 4.2.1.17,5.3.3.18 0.0000000000000000000000000000000000000000000000000006385 195.0
HKD2_k127_5136978_92 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000005454 195.0
HKD2_k127_5136978_93 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000003024 181.0
HKD2_k127_5136978_94 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000003448 173.0
HKD2_k127_5136978_95 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000007973 178.0
HKD2_k127_5136978_96 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001442 171.0
HKD2_k127_5136978_97 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000002049 177.0
HKD2_k127_5136978_98 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000002426 182.0
HKD2_k127_5136978_99 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000003022 174.0
HKD2_k127_5189209_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 527.0
HKD2_k127_5189209_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 477.0
HKD2_k127_5189209_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 431.0
HKD2_k127_5189209_3 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 409.0
HKD2_k127_5189209_4 PFAM Rieske 2Fe-2S K16937 - 1.8.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000003737 255.0
HKD2_k127_5189209_5 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003769 234.0
HKD2_k127_5189209_6 - - - - 0.0000000000000000003989 94.0
HKD2_k127_5189209_7 - - - - 0.000000000000002022 79.0
HKD2_k127_5323523_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1283.0
HKD2_k127_5323523_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1069.0
HKD2_k127_5323523_10 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 392.0
HKD2_k127_5323523_11 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 287.0
HKD2_k127_5323523_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002123 285.0
HKD2_k127_5323523_13 Lipopolysaccharide biosynthesis protein K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 289.0
HKD2_k127_5323523_14 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004432 264.0
HKD2_k127_5323523_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006147 265.0
HKD2_k127_5323523_16 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003569 253.0
HKD2_k127_5323523_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001748 238.0
HKD2_k127_5323523_18 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000004749 238.0
HKD2_k127_5323523_19 Methionine aminopeptidase K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016020,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000007949 248.0
HKD2_k127_5323523_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 4.946e-218 680.0
HKD2_k127_5323523_20 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003 233.0
HKD2_k127_5323523_21 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000002062 226.0
HKD2_k127_5323523_22 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HKD2_k127_5323523_23 transferase activity, transferring glycosyl groups K16703 - - 0.000000000000000000000000000000000000000000000000000000000000005941 231.0
HKD2_k127_5323523_24 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000007278 225.0
HKD2_k127_5323523_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001109 209.0
HKD2_k127_5323523_26 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002605 221.0
HKD2_k127_5323523_27 - - - - 0.0000000000000000000000000000000000000000000000000000002155 218.0
HKD2_k127_5323523_28 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001559 189.0
HKD2_k127_5323523_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000804 173.0
HKD2_k127_5323523_3 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 570.0
HKD2_k127_5323523_30 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000002019 196.0
HKD2_k127_5323523_31 Adenylate kinase K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000007854 175.0
HKD2_k127_5323523_32 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000008079 183.0
HKD2_k127_5323523_33 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000009798 163.0
HKD2_k127_5323523_34 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000005457 169.0
HKD2_k127_5323523_35 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000001191 184.0
HKD2_k127_5323523_36 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000001843 176.0
HKD2_k127_5323523_37 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000003516 169.0
HKD2_k127_5323523_38 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000004802 163.0
HKD2_k127_5323523_39 AAA domain - - - 0.00000000000000000000000000000000006782 153.0
HKD2_k127_5323523_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 518.0
HKD2_k127_5323523_40 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000002011 147.0
HKD2_k127_5323523_41 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001095 132.0
HKD2_k127_5323523_42 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000001111 139.0
HKD2_k127_5323523_43 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000001863 137.0
HKD2_k127_5323523_44 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002894 124.0
HKD2_k127_5323523_45 Glycosyl transferase family 4 - - - 0.00000000000000000000000000000314 138.0
HKD2_k127_5323523_46 - - - - 0.000000000000000000000000000003337 138.0
HKD2_k127_5323523_47 Glycosyl transferases group 1 - - - 0.00000000000000000000000000001058 135.0
HKD2_k127_5323523_48 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001498 120.0
HKD2_k127_5323523_49 Tetratricopeptide repeat - - - 0.000000000000000000000000002964 121.0
HKD2_k127_5323523_5 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 497.0
HKD2_k127_5323523_50 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000005388 110.0
HKD2_k127_5323523_51 Sulfotransferase family - - - 0.0000000000000000000000001026 117.0
HKD2_k127_5323523_52 carbohydrate metabolic process K21014 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009311,GO:0009987,GO:0016020,GO:0016740,GO:0016782,GO:0017076,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044272,GO:0044281,GO:0044464,GO:0046483,GO:0046505,GO:0046506,GO:0046983,GO:0050427,GO:0050656,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901681 2.8.2.37 0.0000000000000000000003144 107.0
HKD2_k127_5323523_53 Sulfotransferase family - - - 0.00000000000000000001339 103.0
HKD2_k127_5323523_54 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000734 82.0
HKD2_k127_5323523_55 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000008451 77.0
HKD2_k127_5323523_56 Acetyltransferase (GNAT) family - - - 0.00000000002171 77.0
HKD2_k127_5323523_6 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 457.0
HKD2_k127_5323523_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 446.0
HKD2_k127_5323523_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 401.0
HKD2_k127_5323523_9 ATPases associated with a variety of cellular activities K01990,K09691,K09693 - 3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 396.0
HKD2_k127_5511224_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.428e-240 757.0
HKD2_k127_5511224_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.03e-238 752.0
HKD2_k127_5511224_10 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 392.0
HKD2_k127_5511224_11 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 378.0
HKD2_k127_5511224_12 Evidence 5 No homology to any previously reported sequences K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 383.0
HKD2_k127_5511224_13 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 367.0
HKD2_k127_5511224_14 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
HKD2_k127_5511224_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 330.0
HKD2_k127_5511224_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 315.0
HKD2_k127_5511224_17 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 320.0
HKD2_k127_5511224_18 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 296.0
HKD2_k127_5511224_19 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 306.0
HKD2_k127_5511224_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.68e-203 655.0
HKD2_k127_5511224_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006691 278.0
HKD2_k127_5511224_21 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006122 277.0
HKD2_k127_5511224_22 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 268.0
HKD2_k127_5511224_23 branched-chain amino acid transmembrane transporter activity K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004786 261.0
HKD2_k127_5511224_24 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000009985 250.0
HKD2_k127_5511224_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000173 232.0
HKD2_k127_5511224_26 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000007901 231.0
HKD2_k127_5511224_27 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001814 224.0
HKD2_k127_5511224_28 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000002209 230.0
HKD2_k127_5511224_29 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000001577 201.0
HKD2_k127_5511224_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 587.0
HKD2_k127_5511224_30 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000817 184.0
HKD2_k127_5511224_31 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000006176 163.0
HKD2_k127_5511224_32 Nitroreductase family - - - 0.0000000000000000000000000000000000000004031 164.0
HKD2_k127_5511224_33 - - - - 0.0000000000000000000000000000000000000009207 156.0
HKD2_k127_5511224_34 phosphatase activity K07025 - - 0.0000000000000000000000000000000000001404 153.0
HKD2_k127_5511224_35 MaoC domain-containing protein dehydratase - - - 0.000000000000000000000000000000000354 143.0
HKD2_k127_5511224_36 RF-1 domain K15034 - - 0.000000000000000000000000000000003556 133.0
HKD2_k127_5511224_37 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000001588 134.0
HKD2_k127_5511224_38 transcriptional regulator - GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001536 116.0
HKD2_k127_5511224_39 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000001508 117.0
HKD2_k127_5511224_4 synthetase K00666 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 527.0
HKD2_k127_5511224_40 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000001814 115.0
HKD2_k127_5511224_42 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000002196 99.0
HKD2_k127_5511224_43 Domain of unknown function (DUF1330) - - - 0.000000000000000006088 91.0
HKD2_k127_5511224_44 transcriptional regulator - - - 0.00000000000000001495 91.0
HKD2_k127_5511224_46 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000009533 74.0
HKD2_k127_5511224_47 peptidyl-tyrosine sulfation - - - 0.000000006198 69.0
HKD2_k127_5511224_48 Transcriptional regulator, MarR family - - - 0.000001425 57.0
HKD2_k127_5511224_49 mercury ion transmembrane transporter activity K07213 - - 0.00004608 55.0
HKD2_k127_5511224_5 belongs to the aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 518.0
HKD2_k127_5511224_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 490.0
HKD2_k127_5511224_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 489.0
HKD2_k127_5511224_8 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 424.0
HKD2_k127_5511224_9 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 413.0
HKD2_k127_5533071_0 UvrD/REP helicase N-terminal domain - - - 8.915e-257 845.0
HKD2_k127_5533071_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K10676 - 1.14.13.20 3.107e-217 689.0
HKD2_k127_5533071_10 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 473.0
HKD2_k127_5533071_11 PFAM monooxygenase FAD-binding K16022,K20943 - 1.14.13.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 450.0
HKD2_k127_5533071_12 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
HKD2_k127_5533071_13 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 421.0
HKD2_k127_5533071_14 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 400.0
HKD2_k127_5533071_15 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 375.0
HKD2_k127_5533071_16 Electron transfer flavoprotein FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 357.0
HKD2_k127_5533071_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 334.0
HKD2_k127_5533071_18 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 345.0
HKD2_k127_5533071_19 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 339.0
HKD2_k127_5533071_2 PFAM Amidohydrolase 2 - - - 3.055e-209 658.0
HKD2_k127_5533071_20 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 323.0
HKD2_k127_5533071_21 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 315.0
HKD2_k127_5533071_22 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 311.0
HKD2_k127_5533071_23 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 306.0
HKD2_k127_5533071_24 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 319.0
HKD2_k127_5533071_25 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001548 273.0
HKD2_k127_5533071_26 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004133 284.0
HKD2_k127_5533071_27 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
HKD2_k127_5533071_28 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004412 259.0
HKD2_k127_5533071_29 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
HKD2_k127_5533071_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 600.0
HKD2_k127_5533071_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000414 249.0
HKD2_k127_5533071_31 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009682 257.0
HKD2_k127_5533071_32 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002325 264.0
HKD2_k127_5533071_33 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000004154 241.0
HKD2_k127_5533071_34 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
HKD2_k127_5533071_35 - - - - 0.000000000000000000000000000000000000000000002693 182.0
HKD2_k127_5533071_36 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000001123 183.0
HKD2_k127_5533071_37 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000209 169.0
HKD2_k127_5533071_38 - - - - 0.0000000000000000000000000000000000000000004046 183.0
HKD2_k127_5533071_39 hmm pf02397 - - - 0.0000000000000000000000000000000000000000007577 166.0
HKD2_k127_5533071_4 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 556.0
HKD2_k127_5533071_40 transcriptional regulator - - - 0.000000000000000000000000000000000000000006869 162.0
HKD2_k127_5533071_41 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000005508 156.0
HKD2_k127_5533071_43 integral membrane protein - - - 0.00000000000000000000000000000000000008281 154.0
HKD2_k127_5533071_44 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000122 148.0
HKD2_k127_5533071_45 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000000004831 128.0
HKD2_k127_5533071_46 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000001268 137.0
HKD2_k127_5533071_47 - - - - 0.00000000000000000000000000000242 132.0
HKD2_k127_5533071_48 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000006277 127.0
HKD2_k127_5533071_49 Dodecin K09165 - - 0.0000000000000000000000000002147 116.0
HKD2_k127_5533071_5 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 520.0
HKD2_k127_5533071_50 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000000000000005043 121.0
HKD2_k127_5533071_51 C4-type zinc ribbon domain K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000006306 119.0
HKD2_k127_5533071_52 - - - - 0.0000000000000000008226 89.0
HKD2_k127_5533071_53 - - - - 0.00000000000000001685 87.0
HKD2_k127_5533071_54 Transcription factor WhiB - - - 0.00000000000000004855 86.0
HKD2_k127_5533071_55 - - - - 0.0000000000000009697 87.0
HKD2_k127_5533071_56 2TM domain - - - 0.0000000007859 65.0
HKD2_k127_5533071_58 - - - - 0.000002895 52.0
HKD2_k127_5533071_59 Endonuclease Exonuclease phosphatase - - - 0.00001029 57.0
HKD2_k127_5533071_6 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 479.0
HKD2_k127_5533071_60 Pectate lyase superfamily protein - - - 0.000157 55.0
HKD2_k127_5533071_61 Helix-turn-helix domain - - - 0.0007881 51.0
HKD2_k127_5533071_62 - - - - 0.0009448 50.0
HKD2_k127_5533071_7 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 479.0
HKD2_k127_5533071_8 NADH:flavin oxidoreductase / NADH oxidase family K22347 - 1.8.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 475.0
HKD2_k127_5533071_9 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 473.0
HKD2_k127_586918_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
HKD2_k127_586918_1 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 585.0
HKD2_k127_586918_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000312 271.0
HKD2_k127_586918_11 ABC-type sugar transport system, periplasmic component K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004402 276.0
HKD2_k127_586918_12 ABC transporter (Permease K02025,K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003039 256.0
HKD2_k127_586918_13 ABC-type sugar transport system, periplasmic component K05813 - - 0.000000000000000000000000000000000000000000000000000000000000001706 250.0
HKD2_k127_586918_14 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000006704 226.0
HKD2_k127_586918_15 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000009194 215.0
HKD2_k127_586918_16 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000007353 207.0
HKD2_k127_586918_17 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000003225 211.0
HKD2_k127_586918_18 - - - - 0.0000000000000000000000000002202 132.0
HKD2_k127_586918_19 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000001041 117.0
HKD2_k127_586918_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 504.0
HKD2_k127_586918_20 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000006028 96.0
HKD2_k127_586918_21 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.0000000000000000001484 104.0
HKD2_k127_586918_22 - K20276 - - 0.00000000002442 78.0
HKD2_k127_586918_23 - - - - 0.0000000005022 72.0
HKD2_k127_586918_24 Phage integrase family - - - 0.00003002 48.0
HKD2_k127_586918_3 Belongs to the ABC transporter superfamily K05816,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 373.0
HKD2_k127_586918_4 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 368.0
HKD2_k127_586918_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 345.0
HKD2_k127_586918_6 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 331.0
HKD2_k127_586918_7 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 304.0
HKD2_k127_586918_8 AMP-binding enzyme C-terminal domain K04116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005504 290.0
HKD2_k127_586918_9 COG0395 ABC-type sugar transport system, permease component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003182 274.0
HKD2_k127_6079009_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 467.0
HKD2_k127_6079009_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002572 280.0
HKD2_k127_6079009_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000000000000000000000000001561 144.0
HKD2_k127_6079009_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000002959 110.0
HKD2_k127_6079009_4 lactoylglutathione lyase activity - - - 0.00000000000000000002988 95.0
HKD2_k127_6079009_5 positive regulation of growth - - - 0.00000000007033 68.0
HKD2_k127_6079009_6 Chlorite dismutase - - - 0.00000003774 64.0
HKD2_k127_6079009_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00006777 50.0
HKD2_k127_6079009_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0001011 44.0
HKD2_k127_6521318_0 Beta galactosidase small chain K01190 - 3.2.1.23 8.356e-268 859.0
HKD2_k127_6521318_1 Beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 510.0
HKD2_k127_6521318_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
HKD2_k127_6521318_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 395.0
HKD2_k127_6521318_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 327.0
HKD2_k127_6521318_5 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000001094 177.0
HKD2_k127_6521318_6 Acetyltransferase (GNAT) family K06976 - - 0.00000000000000000000000000000000000000003003 164.0
HKD2_k127_6521318_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000004111 50.0
HKD2_k127_6577842_0 Amidohydrolase family - - - 3.027e-250 782.0
HKD2_k127_6577842_1 2-nitropropane dioxygenase - - - 4.756e-219 683.0
HKD2_k127_6577842_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 304.0
HKD2_k127_6577842_11 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009573 293.0
HKD2_k127_6577842_12 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
HKD2_k127_6577842_13 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
HKD2_k127_6577842_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000001555 216.0
HKD2_k127_6577842_15 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000154 184.0
HKD2_k127_6577842_16 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000004012 177.0
HKD2_k127_6577842_17 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000001683 174.0
HKD2_k127_6577842_18 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000002669 160.0
HKD2_k127_6577842_19 response to heat K07090 - - 0.000000000000000000000000000000000000006488 154.0
HKD2_k127_6577842_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.751e-199 633.0
HKD2_k127_6577842_20 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000003042 159.0
HKD2_k127_6577842_21 TOBE domain - - - 0.0000000000000000000000000000000000006063 147.0
HKD2_k127_6577842_22 - - - - 0.000000000000000000000000003313 117.0
HKD2_k127_6577842_23 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000004356 104.0
HKD2_k127_6577842_24 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000905 99.0
HKD2_k127_6577842_25 - - - - 0.000000000000005468 84.0
HKD2_k127_6577842_26 - - - - 0.0000000000005198 76.0
HKD2_k127_6577842_27 Domain of unknown function (DUF222) K07451 - - 0.00000635 55.0
HKD2_k127_6577842_3 PFAM glycoside hydrolase, family 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 534.0
HKD2_k127_6577842_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 538.0
HKD2_k127_6577842_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 499.0
HKD2_k127_6577842_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 401.0
HKD2_k127_6577842_7 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 366.0
HKD2_k127_6577842_8 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 356.0
HKD2_k127_6577842_9 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 304.0
HKD2_k127_666837_0 Sulfatase - - - 5.413e-269 847.0
HKD2_k127_666837_1 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 2.956e-245 796.0
HKD2_k127_666837_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 475.0
HKD2_k127_666837_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000461 272.0
HKD2_k127_666837_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 239.0
HKD2_k127_666837_5 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000002777 224.0
HKD2_k127_666837_6 cytochrome - - - 0.000000000000000000000000000000002322 135.0
HKD2_k127_666837_7 SnoaL-like domain - - - 0.0000000000000000001277 97.0
HKD2_k127_666837_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000004475 69.0
HKD2_k127_666837_9 Sporulation and spore germination - - - 0.000000004645 67.0
HKD2_k127_6794045_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1370.0
HKD2_k127_6794045_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 2.166e-296 923.0
HKD2_k127_6794045_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 439.0
HKD2_k127_6794045_11 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 431.0
HKD2_k127_6794045_12 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 421.0
HKD2_k127_6794045_13 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
HKD2_k127_6794045_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 414.0
HKD2_k127_6794045_15 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 406.0
HKD2_k127_6794045_16 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 363.0
HKD2_k127_6794045_17 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 374.0
HKD2_k127_6794045_18 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 347.0
HKD2_k127_6794045_19 Enoyl- acyl-carrier-protein reductase NADH K00208,K11611 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 357.0
HKD2_k127_6794045_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.998e-270 857.0
HKD2_k127_6794045_20 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 343.0
HKD2_k127_6794045_21 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
HKD2_k127_6794045_22 Displays ATPase and GTPase activities K06958 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 338.0
HKD2_k127_6794045_23 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 347.0
HKD2_k127_6794045_24 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 322.0
HKD2_k127_6794045_25 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 308.0
HKD2_k127_6794045_26 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 306.0
HKD2_k127_6794045_27 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 290.0
HKD2_k127_6794045_28 Sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002288 272.0
HKD2_k127_6794045_29 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000554 278.0
HKD2_k127_6794045_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.408e-238 766.0
HKD2_k127_6794045_30 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001969 262.0
HKD2_k127_6794045_31 ANTAR K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000000008961 233.0
HKD2_k127_6794045_32 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000001463 250.0
HKD2_k127_6794045_33 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000008238 233.0
HKD2_k127_6794045_34 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000001328 243.0
HKD2_k127_6794045_35 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000002828 228.0
HKD2_k127_6794045_36 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000006014 217.0
HKD2_k127_6794045_37 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000007887 226.0
HKD2_k127_6794045_38 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.00000000000000000000000000000000000000000000000000000007046 210.0
HKD2_k127_6794045_39 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000003585 202.0
HKD2_k127_6794045_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.988e-214 687.0
HKD2_k127_6794045_40 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000005363 201.0
HKD2_k127_6794045_41 Major facilitator Superfamily K08369 - - 0.000000000000000000000000000000000000000000000000008055 204.0
HKD2_k127_6794045_42 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000002067 202.0
HKD2_k127_6794045_43 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000005709 170.0
HKD2_k127_6794045_44 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000281 166.0
HKD2_k127_6794045_45 - - - - 0.00000000000000000000001296 112.0
HKD2_k127_6794045_46 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000211 92.0
HKD2_k127_6794045_47 - - - - 0.00000000000000004156 85.0
HKD2_k127_6794045_48 Preprotein translocase SecG subunit K03075 - - 0.00000000000000262 78.0
HKD2_k127_6794045_49 - - - - 0.000000000000007466 78.0
HKD2_k127_6794045_5 Ribosomal protein S1-like RNA-binding domain K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 4.165e-194 627.0
HKD2_k127_6794045_50 O-Antigen ligase - - - 0.00000000003301 76.0
HKD2_k127_6794045_51 membrane protein (DUF2078) K08982 - - 0.00000000005507 66.0
HKD2_k127_6794045_52 ester cyclase - - - 0.00000001712 61.0
HKD2_k127_6794045_53 - - - - 0.000002045 57.0
HKD2_k127_6794045_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 548.0
HKD2_k127_6794045_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 514.0
HKD2_k127_6794045_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 517.0
HKD2_k127_6794045_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 460.0
HKD2_k127_6815562_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.965e-319 1012.0
HKD2_k127_6815562_1 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 2.686e-276 867.0
HKD2_k127_6815562_10 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 469.0
HKD2_k127_6815562_11 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 471.0
HKD2_k127_6815562_12 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 426.0
HKD2_k127_6815562_13 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 421.0
HKD2_k127_6815562_14 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 416.0
HKD2_k127_6815562_15 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 404.0
HKD2_k127_6815562_16 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 399.0
HKD2_k127_6815562_17 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 386.0
HKD2_k127_6815562_18 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 381.0
HKD2_k127_6815562_19 Phosphate acyltransferases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 358.0
HKD2_k127_6815562_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.528e-235 745.0
HKD2_k127_6815562_20 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 357.0
HKD2_k127_6815562_21 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 363.0
HKD2_k127_6815562_22 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 366.0
HKD2_k127_6815562_23 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 357.0
HKD2_k127_6815562_24 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 329.0
HKD2_k127_6815562_25 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 321.0
HKD2_k127_6815562_26 PFAM MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 295.0
HKD2_k127_6815562_27 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 301.0
HKD2_k127_6815562_28 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 287.0
HKD2_k127_6815562_29 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005186 286.0
HKD2_k127_6815562_3 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 4.856e-206 661.0
HKD2_k127_6815562_30 transport, permease protein K01992,K18233 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003565 292.0
HKD2_k127_6815562_31 Epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000429 303.0
HKD2_k127_6815562_32 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005375 274.0
HKD2_k127_6815562_33 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007896 273.0
HKD2_k127_6815562_34 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009013 281.0
HKD2_k127_6815562_35 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 265.0
HKD2_k127_6815562_36 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009775 265.0
HKD2_k127_6815562_37 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005764 254.0
HKD2_k127_6815562_38 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000785 253.0
HKD2_k127_6815562_39 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000004362 237.0
HKD2_k127_6815562_4 ABC transporter transmembrane region K06147 - - 7.413e-203 654.0
HKD2_k127_6815562_40 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000002843 240.0
HKD2_k127_6815562_41 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000002655 225.0
HKD2_k127_6815562_42 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000002837 227.0
HKD2_k127_6815562_43 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000002903 223.0
HKD2_k127_6815562_44 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000003573 211.0
HKD2_k127_6815562_45 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000002228 220.0
HKD2_k127_6815562_46 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
HKD2_k127_6815562_47 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000007199 217.0
HKD2_k127_6815562_48 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000001163 203.0
HKD2_k127_6815562_49 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000005321 210.0
HKD2_k127_6815562_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 612.0
HKD2_k127_6815562_50 Acetoacetate decarboxylase (ADC) - - - 0.00000000000000000000000000000000000000000000000000002082 203.0
HKD2_k127_6815562_51 - - - - 0.00000000000000000000000000000000000000000000000000007363 206.0
HKD2_k127_6815562_52 PFAM flavin reductase K16048 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016645,GO:0016646,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000000000000000000000000000000000002895 188.0
HKD2_k127_6815562_53 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000001799 184.0
HKD2_k127_6815562_54 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000003179 188.0
HKD2_k127_6815562_55 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000000000000000000000000000001667 175.0
HKD2_k127_6815562_56 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000002056 171.0
HKD2_k127_6815562_57 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000002311 171.0
HKD2_k127_6815562_58 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000001219 157.0
HKD2_k127_6815562_59 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000326 145.0
HKD2_k127_6815562_6 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 600.0
HKD2_k127_6815562_60 GHMP kinases N terminal domain K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000417 150.0
HKD2_k127_6815562_61 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000003495 143.0
HKD2_k127_6815562_62 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000004037 144.0
HKD2_k127_6815562_63 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000001064 135.0
HKD2_k127_6815562_64 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000008792 142.0
HKD2_k127_6815562_65 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004659 126.0
HKD2_k127_6815562_66 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000000007302 123.0
HKD2_k127_6815562_67 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000003505 114.0
HKD2_k127_6815562_68 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000004456 112.0
HKD2_k127_6815562_69 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000009084 123.0
HKD2_k127_6815562_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 539.0
HKD2_k127_6815562_70 SnoaL-like domain - - - 0.0000000000000000000000003039 109.0
HKD2_k127_6815562_71 NlpC/P60 family K21471 - - 0.000000000000000000000000339 119.0
HKD2_k127_6815562_72 - - - - 0.000000000000000000000103 105.0
HKD2_k127_6815562_73 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000001083 108.0
HKD2_k127_6815562_74 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000002477 98.0
HKD2_k127_6815562_75 AbrB family transcriptional regulator K06284 - - 0.00000000000000003831 84.0
HKD2_k127_6815562_76 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.0000000000000006669 89.0
HKD2_k127_6815562_77 - - - - 0.00000000000005434 79.0
HKD2_k127_6815562_78 G5 domain protein - - - 0.0000000000003305 83.0
HKD2_k127_6815562_79 endonuclease exonuclease phosphatase - - - 0.000000000001045 80.0
HKD2_k127_6815562_8 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 515.0
HKD2_k127_6815562_80 peptidase S1 and S6, chymotrypsin Hap K08372 - - 0.0000000002379 71.0
HKD2_k127_6815562_81 - - - - 0.00000004765 63.0
HKD2_k127_6815562_83 Lytic transglycolase - - - 0.000004522 59.0
HKD2_k127_6815562_9 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 470.0
HKD2_k127_6821017_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 7.272e-304 945.0
HKD2_k127_6821017_1 Glycosyl Transferase - - - 2.437e-288 912.0
HKD2_k127_6821017_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 565.0
HKD2_k127_6821017_11 belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 560.0
HKD2_k127_6821017_12 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 553.0
HKD2_k127_6821017_13 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 499.0
HKD2_k127_6821017_14 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 383.0
HKD2_k127_6821017_15 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 378.0
HKD2_k127_6821017_16 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 377.0
HKD2_k127_6821017_17 response regulator, receiver K02483,K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 344.0
HKD2_k127_6821017_18 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 327.0
HKD2_k127_6821017_19 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 336.0
HKD2_k127_6821017_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.825e-287 903.0
HKD2_k127_6821017_20 PFAM Type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 329.0
HKD2_k127_6821017_21 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 314.0
HKD2_k127_6821017_22 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 312.0
HKD2_k127_6821017_23 haloacid dehalogenase-like hydrolase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
HKD2_k127_6821017_25 Transmembrane secretion effector K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 308.0
HKD2_k127_6821017_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005645 266.0
HKD2_k127_6821017_27 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002578 256.0
HKD2_k127_6821017_28 Pfam SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
HKD2_k127_6821017_29 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004679 244.0
HKD2_k127_6821017_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097 5.99.1.2 9.869e-286 906.0
HKD2_k127_6821017_30 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000009218 248.0
HKD2_k127_6821017_31 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000001065 249.0
HKD2_k127_6821017_32 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000005406 233.0
HKD2_k127_6821017_33 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000008484 214.0
HKD2_k127_6821017_34 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
HKD2_k127_6821017_35 - - - - 0.0000000000000000000000000000000000000000000000000000008434 201.0
HKD2_k127_6821017_36 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000009955 211.0
HKD2_k127_6821017_37 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000009393 194.0
HKD2_k127_6821017_38 FMN binding - - - 0.00000000000000000000000000000000000000000000000002563 185.0
HKD2_k127_6821017_39 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000004707 191.0
HKD2_k127_6821017_4 His Kinase A (phosphoacceptor) domain - - - 2.285e-271 858.0
HKD2_k127_6821017_40 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000003783 176.0
HKD2_k127_6821017_41 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000001445 167.0
HKD2_k127_6821017_42 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000001457 176.0
HKD2_k127_6821017_43 Right handed beta helix region - - - 0.0000000000000000000000000000000000001322 159.0
HKD2_k127_6821017_44 Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000001642 147.0
HKD2_k127_6821017_45 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000001319 151.0
HKD2_k127_6821017_46 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000002778 147.0
HKD2_k127_6821017_47 EamA-like transporter family - - - 0.0000000000000000000000000000007747 139.0
HKD2_k127_6821017_48 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.000000000000000000000001215 113.0
HKD2_k127_6821017_49 DNA polymerase III K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000002236 102.0
HKD2_k127_6821017_5 DEAH box helicase K06877 - - 2.4e-219 706.0
HKD2_k127_6821017_50 Amino acid permease - - - 0.0000000000000000002486 92.0
HKD2_k127_6821017_53 - - - - 0.00000000000000001119 94.0
HKD2_k127_6821017_54 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000001953 88.0
HKD2_k127_6821017_55 - - - - 0.000000000000006868 78.0
HKD2_k127_6821017_56 Pentapeptide repeat protein - - - 0.000000002912 67.0
HKD2_k127_6821017_57 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000114 63.0
HKD2_k127_6821017_58 4Fe-4S dicluster domain - - - 0.0000002472 63.0
HKD2_k127_6821017_59 Glycosyl hydrolase family 71 - - - 0.0000007504 62.0
HKD2_k127_6821017_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 5.582e-217 688.0
HKD2_k127_6821017_60 TadE-like protein - - - 0.00002967 53.0
HKD2_k127_6821017_62 Scramblase - - - 0.0001093 54.0
HKD2_k127_6821017_63 Type II secretion system K12510 - - 0.0002877 53.0
HKD2_k127_6821017_64 PFAM Type II secretion system F K12511 - - 0.0008517 52.0
HKD2_k127_6821017_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 6.747e-210 687.0
HKD2_k127_6821017_8 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 582.0
HKD2_k127_6821017_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 539.0
HKD2_k127_6883536_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.715e-200 629.0
HKD2_k127_6883536_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 594.0
HKD2_k127_6883536_10 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002887 258.0
HKD2_k127_6883536_11 cyclic nucleotide-binding - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000001533 219.0
HKD2_k127_6883536_12 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000001013 205.0
HKD2_k127_6883536_13 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000002937 160.0
HKD2_k127_6883536_14 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000003553 176.0
HKD2_k127_6883536_15 Domain of unknown function (DUF4114) - - - 0.0000000000000001077 96.0
HKD2_k127_6883536_16 helix_turn_helix, Lux Regulon - - - 0.00000000001309 74.0
HKD2_k127_6883536_17 IgGFc binding protein - - - 0.00000000215 72.0
HKD2_k127_6883536_2 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 586.0
HKD2_k127_6883536_3 AMP-binding enzyme K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 569.0
HKD2_k127_6883536_4 IMP dehydrogenase / GMP reductase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 428.0
HKD2_k127_6883536_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 387.0
HKD2_k127_6883536_6 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 367.0
HKD2_k127_6883536_7 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
HKD2_k127_6883536_8 Short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 333.0
HKD2_k127_6883536_9 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 327.0
HKD2_k127_7169360_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1442.0
HKD2_k127_7169360_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.236e-298 936.0
HKD2_k127_7169360_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 559.0
HKD2_k127_7169360_100 Glycosyltransferase family 87 - - - 0.000000003834 71.0
HKD2_k127_7169360_101 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000004146 64.0
HKD2_k127_7169360_102 Acyltransferase family - - - 0.000000005224 65.0
HKD2_k127_7169360_103 - - - - 0.000000007847 58.0
HKD2_k127_7169360_104 Putative zinc-finger - - - 0.00000001509 65.0
HKD2_k127_7169360_106 Polyketide cyclase / dehydrase and lipid transport - - - 0.000001692 56.0
HKD2_k127_7169360_107 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000002845 57.0
HKD2_k127_7169360_108 YceI-like domain - - - 0.00002829 53.0
HKD2_k127_7169360_11 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 507.0
HKD2_k127_7169360_110 chitin binding K01183 - 3.2.1.14 0.0006419 52.0
HKD2_k127_7169360_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 503.0
HKD2_k127_7169360_13 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
HKD2_k127_7169360_14 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 490.0
HKD2_k127_7169360_15 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 464.0
HKD2_k127_7169360_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 449.0
HKD2_k127_7169360_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 407.0
HKD2_k127_7169360_18 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 412.0
HKD2_k127_7169360_19 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 426.0
HKD2_k127_7169360_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.901e-254 831.0
HKD2_k127_7169360_20 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 412.0
HKD2_k127_7169360_21 cytochrome p450 K16046 - 1.14.13.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 402.0
HKD2_k127_7169360_22 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 425.0
HKD2_k127_7169360_23 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 400.0
HKD2_k127_7169360_24 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 410.0
HKD2_k127_7169360_25 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 390.0
HKD2_k127_7169360_26 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 373.0
HKD2_k127_7169360_27 FAD dependent oxidoreductase K16051 - 1.3.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 380.0
HKD2_k127_7169360_28 PFAM Taurine catabolism dioxygenase TauD TfdA K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 353.0
HKD2_k127_7169360_29 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 351.0
HKD2_k127_7169360_3 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.772e-249 796.0
HKD2_k127_7169360_30 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 357.0
HKD2_k127_7169360_31 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 344.0
HKD2_k127_7169360_32 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 344.0
HKD2_k127_7169360_33 Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
HKD2_k127_7169360_34 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 333.0
HKD2_k127_7169360_35 aldo keto reductase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 335.0
HKD2_k127_7169360_36 Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
HKD2_k127_7169360_37 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 333.0
HKD2_k127_7169360_38 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 317.0
HKD2_k127_7169360_39 Wax ester synthase-like Acyl-CoA acyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 327.0
HKD2_k127_7169360_4 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 5.386e-242 773.0
HKD2_k127_7169360_40 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 325.0
HKD2_k127_7169360_41 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 310.0
HKD2_k127_7169360_42 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 306.0
HKD2_k127_7169360_43 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 311.0
HKD2_k127_7169360_44 Male sterility protein K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 298.0
HKD2_k127_7169360_45 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 286.0
HKD2_k127_7169360_46 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 286.0
HKD2_k127_7169360_47 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001689 281.0
HKD2_k127_7169360_48 L-lysine catabolic process to acetate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002213 257.0
HKD2_k127_7169360_49 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000293 262.0
HKD2_k127_7169360_5 Retinal pigment epithelial membrane protein K11159 - - 1.117e-218 709.0
HKD2_k127_7169360_50 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003277 263.0
HKD2_k127_7169360_51 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001823 250.0
HKD2_k127_7169360_52 PFAM Protein kinase K08282,K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002613 269.0
HKD2_k127_7169360_53 ABC transporter substrate-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000113 259.0
HKD2_k127_7169360_54 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002201 241.0
HKD2_k127_7169360_55 LGFP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 242.0
HKD2_k127_7169360_56 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008051 232.0
HKD2_k127_7169360_57 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
HKD2_k127_7169360_58 Amino acid kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005367 237.0
HKD2_k127_7169360_59 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001062 244.0
HKD2_k127_7169360_6 Alpha-glucan phosphorylase K00688 - 2.4.1.1 2.098e-201 685.0
HKD2_k127_7169360_60 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
HKD2_k127_7169360_61 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000006472 221.0
HKD2_k127_7169360_62 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001167 231.0
HKD2_k127_7169360_63 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000009815 229.0
HKD2_k127_7169360_64 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003301 227.0
HKD2_k127_7169360_65 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000002782 220.0
HKD2_k127_7169360_66 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000001348 187.0
HKD2_k127_7169360_67 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000002393 203.0
HKD2_k127_7169360_68 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000003307 200.0
HKD2_k127_7169360_69 chitinase activity - - - 0.000000000000000000000000000000000000000000002941 182.0
HKD2_k127_7169360_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 582.0
HKD2_k127_7169360_70 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000007768 178.0
HKD2_k127_7169360_71 Flavodoxin domain - - - 0.00000000000000000000000000000000000000000001715 169.0
HKD2_k127_7169360_72 sirohydrochlorin ferrochelatase K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.00000000000000000000000000000000000000004047 156.0
HKD2_k127_7169360_73 MgtC family K07507 - - 0.000000000000000000000000000000000000002175 152.0
HKD2_k127_7169360_75 Guanosine polyphosphate - - - 0.000000000000000000000000000000000291 141.0
HKD2_k127_7169360_76 PAS domain - - - 0.000000000000000000000000000000004169 136.0
HKD2_k127_7169360_77 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.000000000000000000000000000000008162 134.0
HKD2_k127_7169360_78 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000002661 135.0
HKD2_k127_7169360_8 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 569.0
HKD2_k127_7169360_80 - - - - 0.0000000000000000000000000000001325 130.0
HKD2_k127_7169360_81 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000668 131.0
HKD2_k127_7169360_82 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001382 130.0
HKD2_k127_7169360_83 cellulase activity - - - 0.00000000000000000000000000009072 135.0
HKD2_k127_7169360_84 Domain of unknown function (DUF4234) - - - 0.000000000000000000000000001607 119.0
HKD2_k127_7169360_85 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000002976 117.0
HKD2_k127_7169360_86 - - - - 0.0000000000000000000000001221 120.0
HKD2_k127_7169360_87 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000001627 109.0
HKD2_k127_7169360_89 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001979 99.0
HKD2_k127_7169360_9 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 579.0
HKD2_k127_7169360_90 2TM domain - - - 0.00000000000000000003331 93.0
HKD2_k127_7169360_91 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000002679 100.0
HKD2_k127_7169360_92 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000003099 94.0
HKD2_k127_7169360_93 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000005563 84.0
HKD2_k127_7169360_94 DoxX K15977 - - 0.0000000000001463 83.0
HKD2_k127_7169360_95 PAS domain - - - 0.0000000000001716 77.0
HKD2_k127_7169360_98 PFAM blue (type 1) copper domain protein - - - 0.0000000001421 70.0
HKD2_k127_7169360_99 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000001447 74.0
HKD2_k127_7240676_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1058.0
HKD2_k127_7240676_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.475e-221 713.0
HKD2_k127_7240676_10 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 541.0
HKD2_k127_7240676_11 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 534.0
HKD2_k127_7240676_12 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 530.0
HKD2_k127_7240676_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 524.0
HKD2_k127_7240676_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 487.0
HKD2_k127_7240676_15 Acyl-CoA dehydrogenase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 489.0
HKD2_k127_7240676_16 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 455.0
HKD2_k127_7240676_17 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 456.0
HKD2_k127_7240676_18 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 456.0
HKD2_k127_7240676_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 458.0
HKD2_k127_7240676_2 PFAM AMP-dependent synthetase and ligase - - - 2.213e-221 703.0
HKD2_k127_7240676_20 protein conserved in bacteria K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 445.0
HKD2_k127_7240676_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 439.0
HKD2_k127_7240676_22 Dihydrodipicolinate reductase, N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 415.0
HKD2_k127_7240676_23 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 403.0
HKD2_k127_7240676_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 387.0
HKD2_k127_7240676_25 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 381.0
HKD2_k127_7240676_26 ThiJ/PfpI family-like K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 372.0
HKD2_k127_7240676_27 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 378.0
HKD2_k127_7240676_28 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 378.0
HKD2_k127_7240676_29 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 351.0
HKD2_k127_7240676_3 Belongs to the thiolase family - - - 1.496e-216 681.0
HKD2_k127_7240676_30 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 340.0
HKD2_k127_7240676_31 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
HKD2_k127_7240676_32 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 339.0
HKD2_k127_7240676_33 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 305.0
HKD2_k127_7240676_34 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 296.0
HKD2_k127_7240676_35 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 310.0
HKD2_k127_7240676_36 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 300.0
HKD2_k127_7240676_37 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 304.0
HKD2_k127_7240676_38 PFAM Wyosine base formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD2_k127_7240676_39 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005532 285.0
HKD2_k127_7240676_4 Pfam Sulfatase - - - 6.041e-213 672.0
HKD2_k127_7240676_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 275.0
HKD2_k127_7240676_41 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 278.0
HKD2_k127_7240676_42 ubiquinone biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009316 273.0
HKD2_k127_7240676_43 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
HKD2_k127_7240676_44 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001605 259.0
HKD2_k127_7240676_45 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002617 254.0
HKD2_k127_7240676_46 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 243.0
HKD2_k127_7240676_47 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005942 247.0
HKD2_k127_7240676_48 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007685 252.0
HKD2_k127_7240676_49 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000003729 224.0
HKD2_k127_7240676_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 601.0
HKD2_k127_7240676_50 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000000001099 209.0
HKD2_k127_7240676_51 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
HKD2_k127_7240676_52 polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HKD2_k127_7240676_53 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000002117 205.0
HKD2_k127_7240676_54 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000002918 206.0
HKD2_k127_7240676_55 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000007662 190.0
HKD2_k127_7240676_56 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000003178 197.0
HKD2_k127_7240676_57 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000000000000000003744 180.0
HKD2_k127_7240676_58 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000001633 185.0
HKD2_k127_7240676_59 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000225 171.0
HKD2_k127_7240676_6 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 588.0
HKD2_k127_7240676_60 MaoC like domain - - - 0.00000000000000000000000000000000000000000003436 175.0
HKD2_k127_7240676_61 - - - - 0.0000000000000000000000000000000000000000001025 175.0
HKD2_k127_7240676_62 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000514 146.0
HKD2_k127_7240676_63 PFAM LmbE family protein - - - 0.00000000000000000000000000000000006394 153.0
HKD2_k127_7240676_64 Pfam Response regulator receiver K07689 - - 0.000000000000000000000000000000006365 133.0
HKD2_k127_7240676_65 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000006333 134.0
HKD2_k127_7240676_66 - - - - 0.0000000000000000000000000000004661 130.0
HKD2_k127_7240676_67 - - - - 0.0000000000000000000000000000266 134.0
HKD2_k127_7240676_68 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000006069 122.0
HKD2_k127_7240676_69 transcriptional regulator - - - 0.0000000000000000000000001845 111.0
HKD2_k127_7240676_7 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 564.0
HKD2_k127_7240676_70 - - - - 0.000000000000000000000001083 112.0
HKD2_k127_7240676_71 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001522 115.0
HKD2_k127_7240676_72 Adenylate cyclase regulatory domain K01768 - 4.6.1.1 0.000000000000000000000235 111.0
HKD2_k127_7240676_73 Belongs to the P(II) protein family K04751,K04752 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000002172 94.0
HKD2_k127_7240676_74 - - - - 0.00000000000000000022 89.0
HKD2_k127_7240676_75 - - - - 0.000000000000000007625 96.0
HKD2_k127_7240676_76 FtsX-like permease family K02004 - - 0.0000000000000008476 92.0
HKD2_k127_7240676_77 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000004263 67.0
HKD2_k127_7240676_78 - - - - 0.0000000009663 70.0
HKD2_k127_7240676_79 4Fe-4S binding domain - - - 0.000000001357 64.0
HKD2_k127_7240676_8 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 564.0
HKD2_k127_7240676_80 Endonuclease/Exonuclease/phosphatase family - - - 0.000000002083 68.0
HKD2_k127_7240676_81 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000002783 61.0
HKD2_k127_7240676_82 - - - - 0.0001281 50.0
HKD2_k127_7240676_83 - - - - 0.000212 51.0
HKD2_k127_7240676_9 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 544.0
HKD2_k127_7293020_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1748.0
HKD2_k127_7293020_1 PFAM transcriptional regulator domain protein - - - 0.0 1237.0
HKD2_k127_7293020_10 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 533.0
HKD2_k127_7293020_11 PFAM Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 494.0
HKD2_k127_7293020_12 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 497.0
HKD2_k127_7293020_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 486.0
HKD2_k127_7293020_14 cytochrome P450 K20497 - 1.14.15.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 479.0
HKD2_k127_7293020_15 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 428.0
HKD2_k127_7293020_16 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 422.0
HKD2_k127_7293020_17 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 416.0
HKD2_k127_7293020_18 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 390.0
HKD2_k127_7293020_19 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 407.0
HKD2_k127_7293020_2 Thiamine pyrophosphate enzyme, central domain - - - 2.211e-276 865.0
HKD2_k127_7293020_20 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 352.0
HKD2_k127_7293020_21 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 342.0
HKD2_k127_7293020_22 COG0402 Cytosine deaminase and related metal-dependent hydrolases K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 348.0
HKD2_k127_7293020_23 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 338.0
HKD2_k127_7293020_24 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 322.0
HKD2_k127_7293020_25 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 310.0
HKD2_k127_7293020_26 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 288.0
HKD2_k127_7293020_27 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000878 286.0
HKD2_k127_7293020_28 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005056 289.0
HKD2_k127_7293020_29 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007813 282.0
HKD2_k127_7293020_3 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.631e-273 852.0
HKD2_k127_7293020_30 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000126 261.0
HKD2_k127_7293020_31 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001803 239.0
HKD2_k127_7293020_32 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
HKD2_k127_7293020_33 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001138 220.0
HKD2_k127_7293020_34 Phenylacetic acid-responsive transcriptional repressor K02616 - - 0.000000000000000000000000000000000000000000000000000000000002233 220.0
HKD2_k127_7293020_35 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K10794 - 1.21.4.1,1.21.4.2 0.0000000000000000000000000000000000000000000000000000000001177 211.0
HKD2_k127_7293020_36 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000001802 217.0
HKD2_k127_7293020_37 Ferritin-like - - - 0.000000000000000000000000000000000000000000000000000000006318 206.0
HKD2_k127_7293020_38 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K19696 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28,2.4.2.44 0.0000000000000000000000000000000000000000000000000000003144 206.0
HKD2_k127_7293020_39 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000002347 195.0
HKD2_k127_7293020_4 Dehydratase family K01687 - 4.2.1.9 4.725e-251 806.0
HKD2_k127_7293020_40 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000003984 188.0
HKD2_k127_7293020_41 FR47-like protein - - - 0.000000000000000000000000000000000000000000000009582 179.0
HKD2_k127_7293020_42 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000004643 174.0
HKD2_k127_7293020_43 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000005212 183.0
HKD2_k127_7293020_44 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.000000000000000000000000000000000000000000002239 166.0
HKD2_k127_7293020_45 Pfam Cation efflux - - - 0.0000000000000000000000000000000000001203 153.0
HKD2_k127_7293020_46 - - - - 0.00000000000000000000000000000000002215 155.0
HKD2_k127_7293020_47 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000002065 150.0
HKD2_k127_7293020_48 - - - - 0.00000000000000000000000000009757 121.0
HKD2_k127_7293020_49 - - - - 0.0000000000000000000000000006571 126.0
HKD2_k127_7293020_5 Lysylphosphatidylglycerol synthase TM region - - - 4.379e-212 685.0
HKD2_k127_7293020_50 pyridoxamine 5-phosphate K05558 - - 0.000000000000000000000000002447 117.0
HKD2_k127_7293020_51 - - - - 0.00000000000000000000000001897 111.0
HKD2_k127_7293020_52 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.0000000000000000000000009095 108.0
HKD2_k127_7293020_54 Endoribonuclease L-PSP - - - 0.000000000000000000000246 102.0
HKD2_k127_7293020_55 NADPH-dependent FMN reductase - - - 0.000000000000000000007435 100.0
HKD2_k127_7293020_56 d-proline reductase K10793 - 1.21.4.1 0.00000000000000000003625 104.0
HKD2_k127_7293020_57 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000135 91.0
HKD2_k127_7293020_58 - - - - 0.00000000000000003274 89.0
HKD2_k127_7293020_59 Putative zinc-finger - - - 0.0000000000000005399 82.0
HKD2_k127_7293020_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 593.0
HKD2_k127_7293020_60 - - - - 0.0000000002188 72.0
HKD2_k127_7293020_61 Domain of unknown function (DUF4328) - - - 0.00000004747 65.0
HKD2_k127_7293020_62 PFAM transcriptional regulator domain protein - - - 0.0000103 59.0
HKD2_k127_7293020_7 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 606.0
HKD2_k127_7293020_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 580.0
HKD2_k127_7293020_9 acetyl-CoA hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 541.0
HKD2_k127_7401425_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1198.0
HKD2_k127_7401425_1 E1-E2 ATPase K12952 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 - 1.073e-244 782.0
HKD2_k127_7401425_10 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 416.0
HKD2_k127_7401425_11 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 347.0
HKD2_k127_7401425_12 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 338.0
HKD2_k127_7401425_13 GlcNAc-PI de-N-acetylase K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 317.0
HKD2_k127_7401425_14 Catalase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 334.0
HKD2_k127_7401425_15 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 302.0
HKD2_k127_7401425_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 307.0
HKD2_k127_7401425_17 phospholipase C K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 313.0
HKD2_k127_7401425_18 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004531 288.0
HKD2_k127_7401425_19 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001609 293.0
HKD2_k127_7401425_2 AAA ATPase domain - - - 3.844e-205 693.0
HKD2_k127_7401425_20 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003351 287.0
HKD2_k127_7401425_21 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003449 274.0
HKD2_k127_7401425_22 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001601 269.0
HKD2_k127_7401425_23 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 256.0
HKD2_k127_7401425_24 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007281 244.0
HKD2_k127_7401425_25 vancomycin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008846 259.0
HKD2_k127_7401425_26 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000006578 235.0
HKD2_k127_7401425_27 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000004429 241.0
HKD2_k127_7401425_28 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000008546 211.0
HKD2_k127_7401425_29 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000233 227.0
HKD2_k127_7401425_3 Ammonium Transporter Family K03320 - - 7.512e-195 623.0
HKD2_k127_7401425_30 Adenylate cyclase regulatory domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000004592 198.0
HKD2_k127_7401425_31 - - - - 0.00000000000000000000000000000000000000000000000001395 201.0
HKD2_k127_7401425_32 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000003516 182.0
HKD2_k127_7401425_33 Acyltransferase - - - 0.000000000000000000000000000000000000000004596 164.0
HKD2_k127_7401425_34 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000007931 158.0
HKD2_k127_7401425_35 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000002761 158.0
HKD2_k127_7401425_37 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000004528 132.0
HKD2_k127_7401425_39 Cupin 2, conserved barrel domain protein K03490 - - 0.000000000000000000000000000002609 124.0
HKD2_k127_7401425_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 623.0
HKD2_k127_7401425_40 L-methionine salvage from methylthioadenosine K00058,K08966 - 1.1.1.399,1.1.1.95,3.1.3.87 0.00000000000000000000008654 115.0
HKD2_k127_7401425_41 GYD domain - - - 0.0000000000000000000004105 101.0
HKD2_k127_7401425_42 SCP-2 sterol transfer family - - - 0.000000000000000000004531 103.0
HKD2_k127_7401425_43 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000002914 93.0
HKD2_k127_7401425_44 PFAM blue (type 1) copper domain protein - - - 0.0000000000002731 76.0
HKD2_k127_7401425_45 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000001408 69.0
HKD2_k127_7401425_46 - - - - 0.000000195 59.0
HKD2_k127_7401425_47 - - - - 0.000002552 60.0
HKD2_k127_7401425_48 Evidence 4 Homologs of previously reported genes of - - - 0.00006632 53.0
HKD2_k127_7401425_5 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 615.0
HKD2_k127_7401425_6 peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 507.0
HKD2_k127_7401425_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 492.0
HKD2_k127_7401425_8 impB/mucB/samB family K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 464.0
HKD2_k127_7401425_9 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 442.0
HKD2_k127_7728471_0 Flavin containing amine oxidoreductase - - - 7.058e-227 723.0
HKD2_k127_7728471_1 Adenylate cyclase - - - 9.111e-227 740.0
HKD2_k127_7728471_10 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 532.0
HKD2_k127_7728471_11 dioxygenase K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 464.0
HKD2_k127_7728471_12 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 444.0
HKD2_k127_7728471_13 Belongs to the FPP GGPP synthase family K13787,K13789 GO:0000287,GO:0003674,GO:0003824,GO:0004161,GO:0004659,GO:0005488,GO:0005506,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0030145,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045337,GO:0045338,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 433.0
HKD2_k127_7728471_14 lipid-transfer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 415.0
HKD2_k127_7728471_15 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 417.0
HKD2_k127_7728471_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 386.0
HKD2_k127_7728471_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HKD2_k127_7728471_18 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 359.0
HKD2_k127_7728471_19 Serine aminopeptidase, S33 K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 353.0
HKD2_k127_7728471_2 amidohydrolase - - - 9.759e-217 686.0
HKD2_k127_7728471_20 Protein of unknown function (DUF2855) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 343.0
HKD2_k127_7728471_21 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 332.0
HKD2_k127_7728471_22 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 321.0
HKD2_k127_7728471_23 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 328.0
HKD2_k127_7728471_24 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006908 276.0
HKD2_k127_7728471_25 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001519 267.0
HKD2_k127_7728471_26 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000001285 241.0
HKD2_k127_7728471_28 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000003127 239.0
HKD2_k127_7728471_29 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000004925 228.0
HKD2_k127_7728471_3 Nitronate monooxygenase - - - 6.357e-216 674.0
HKD2_k127_7728471_30 - - - - 0.000000000000000000000000000000000000000000000000000000000006375 222.0
HKD2_k127_7728471_31 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000005494 182.0
HKD2_k127_7728471_32 clavaminate synthase activity K18058 - 1.14.11.39 0.000000000000000000000000000000000002733 150.0
HKD2_k127_7728471_33 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000421 154.0
HKD2_k127_7728471_34 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000002061 152.0
HKD2_k127_7728471_35 NIPSNAP family containing protein - - - 0.00000000000000000000000000001217 132.0
HKD2_k127_7728471_36 Stress responsive A/B Barrel Domain - - - 0.00000000000000000000000000001981 128.0
HKD2_k127_7728471_37 Thioesterase superfamily - - - 0.000000000000000000000004214 114.0
HKD2_k127_7728471_38 transcriptional regulator - - - 0.00000000000000000000001094 111.0
HKD2_k127_7728471_39 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000004515 103.0
HKD2_k127_7728471_4 amidohydrolase - - - 3.516e-215 676.0
HKD2_k127_7728471_40 Ion transport protein K10716 GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000005136 96.0
HKD2_k127_7728471_41 Helix-turn-helix domain, rpiR family - - - 0.000000000000001922 90.0
HKD2_k127_7728471_42 - - - - 0.000000000000003671 90.0
HKD2_k127_7728471_43 Transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000003394 77.0
HKD2_k127_7728471_5 N-terminal half of MaoC dehydratase - - - 1.892e-198 631.0
HKD2_k127_7728471_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 604.0
HKD2_k127_7728471_7 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 571.0
HKD2_k127_7728471_8 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 551.0
HKD2_k127_7728471_9 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 550.0
HKD2_k127_7774576_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.54e-276 871.0
HKD2_k127_7774576_1 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.802e-271 846.0
HKD2_k127_7774576_10 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 400.0
HKD2_k127_7774576_11 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 396.0
HKD2_k127_7774576_12 Peptidase M1 membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 358.0
HKD2_k127_7774576_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 313.0
HKD2_k127_7774576_14 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 297.0
HKD2_k127_7774576_15 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
HKD2_k127_7774576_16 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000003559 243.0
HKD2_k127_7774576_17 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000002175 230.0
HKD2_k127_7774576_18 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000003565 234.0
HKD2_k127_7774576_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000002344 201.0
HKD2_k127_7774576_2 Oligopeptidase F K08602 - - 2.677e-255 803.0
HKD2_k127_7774576_20 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000001123 189.0
HKD2_k127_7774576_21 Belongs to the phosphoglycerate mutase family K15640 - - 0.00000000000000000000000000000000000000000004933 175.0
HKD2_k127_7774576_22 SnoaL-like domain - - - 0.000000000000000000000000000000000000000001635 165.0
HKD2_k127_7774576_23 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000123 145.0
HKD2_k127_7774576_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 5.058e-215 679.0
HKD2_k127_7774576_4 ATPase component of ABC transporters with duplicated ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 545.0
HKD2_k127_7774576_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 516.0
HKD2_k127_7774576_6 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 492.0
HKD2_k127_7774576_7 DNA helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 514.0
HKD2_k127_7774576_8 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 467.0
HKD2_k127_7774576_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 426.0
HKD2_k127_7794731_0 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 443.0
HKD2_k127_7794731_1 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 344.0
HKD2_k127_7794731_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 340.0
HKD2_k127_7794731_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 331.0
HKD2_k127_7794731_4 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000002412 210.0
HKD2_k127_7794731_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000005002 105.0
HKD2_k127_7794731_6 Domain of unknown function (DUF1905) - - - 0.00000000000006437 78.0
HKD2_k127_7794731_7 Domain of unknown function (DUF1905) - - - 0.00007035 49.0
HKD2_k127_7831392_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1289.0
HKD2_k127_7831392_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1172.0
HKD2_k127_7831392_10 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 592.0
HKD2_k127_7831392_11 Acyl-CoA dehydrogenase N terminal K20035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 557.0
HKD2_k127_7831392_12 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 530.0
HKD2_k127_7831392_13 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 507.0
HKD2_k127_7831392_14 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 486.0
HKD2_k127_7831392_15 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 462.0
HKD2_k127_7831392_16 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 447.0
HKD2_k127_7831392_17 DEAD-like helicases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 451.0
HKD2_k127_7831392_18 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 453.0
HKD2_k127_7831392_19 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 441.0
HKD2_k127_7831392_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1120.0
HKD2_k127_7831392_20 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 436.0
HKD2_k127_7831392_21 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 429.0
HKD2_k127_7831392_22 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
HKD2_k127_7831392_23 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 427.0
HKD2_k127_7831392_24 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 405.0
HKD2_k127_7831392_25 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
HKD2_k127_7831392_26 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 409.0
HKD2_k127_7831392_27 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 422.0
HKD2_k127_7831392_28 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 391.0
HKD2_k127_7831392_29 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
HKD2_k127_7831392_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1018.0
HKD2_k127_7831392_30 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 383.0
HKD2_k127_7831392_31 PFAM ATPase associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 355.0
HKD2_k127_7831392_32 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 349.0
HKD2_k127_7831392_33 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 352.0
HKD2_k127_7831392_34 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 335.0
HKD2_k127_7831392_35 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 344.0
HKD2_k127_7831392_36 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 339.0
HKD2_k127_7831392_37 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 362.0
HKD2_k127_7831392_38 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
HKD2_k127_7831392_39 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003256 292.0
HKD2_k127_7831392_4 radical SAM domain protein - - - 5.13e-296 923.0
HKD2_k127_7831392_40 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001136 289.0
HKD2_k127_7831392_41 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
HKD2_k127_7831392_42 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006593 287.0
HKD2_k127_7831392_43 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
HKD2_k127_7831392_44 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001366 254.0
HKD2_k127_7831392_45 Dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000004109 245.0
HKD2_k127_7831392_46 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000007924 244.0
HKD2_k127_7831392_47 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000001019 243.0
HKD2_k127_7831392_48 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002587 231.0
HKD2_k127_7831392_49 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000002513 242.0
HKD2_k127_7831392_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.635e-282 887.0
HKD2_k127_7831392_50 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000008097 233.0
HKD2_k127_7831392_51 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000002351 228.0
HKD2_k127_7831392_52 Glutamine amidotransferase class-I K02501 - - 0.00000000000000000000000000000000000000000000000000000000000005551 219.0
HKD2_k127_7831392_53 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000178 205.0
HKD2_k127_7831392_54 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000001629 194.0
HKD2_k127_7831392_55 beta-glucosidase K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000001957 197.0
HKD2_k127_7831392_56 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000273 181.0
HKD2_k127_7831392_57 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001893 174.0
HKD2_k127_7831392_58 Belongs to the NUDIX hydrolase family - - - 0.0000000000000000000000000000000000000000004996 165.0
HKD2_k127_7831392_59 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000004628 160.0
HKD2_k127_7831392_6 Cytochrome C and Quinol oxidase polypeptide I K02274,K02827 - 1.10.3.12,1.9.3.1 4.244e-222 705.0
HKD2_k127_7831392_60 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000004871 165.0
HKD2_k127_7831392_61 PFAM helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000008763 164.0
HKD2_k127_7831392_62 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000002837 153.0
HKD2_k127_7831392_63 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000822 152.0
HKD2_k127_7831392_64 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000003175 147.0
HKD2_k127_7831392_65 competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.0000000000000000000000000000000008297 140.0
HKD2_k127_7831392_66 iron dependent repressor - - - 0.0000000000000000000000000000002173 131.0
HKD2_k127_7831392_67 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000001192 122.0
HKD2_k127_7831392_68 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.000000000000000000000000000002378 138.0
HKD2_k127_7831392_69 DNA-directed DNA polymerase activity K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000007874 133.0
HKD2_k127_7831392_7 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 611.0
HKD2_k127_7831392_70 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000008777 123.0
HKD2_k127_7831392_71 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000001664 127.0
HKD2_k127_7831392_72 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001167 127.0
HKD2_k127_7831392_73 tetR family - - - 0.00000000000000000000000006522 115.0
HKD2_k127_7831392_74 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000001426 106.0
HKD2_k127_7831392_75 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000008882 92.0
HKD2_k127_7831392_76 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000734 98.0
HKD2_k127_7831392_77 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139,K01752,K01754 - 2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19 0.000000000000000009251 91.0
HKD2_k127_7831392_78 - - - - 0.0000000000000000297 88.0
HKD2_k127_7831392_79 metallopeptidase activity K01387,K20276 - 3.4.24.3 0.0000000000000002453 95.0
HKD2_k127_7831392_8 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 605.0
HKD2_k127_7831392_80 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000001973 79.0
HKD2_k127_7831392_81 alpha/beta hydrolase fold K07214 - - 0.00000000007369 67.0
HKD2_k127_7831392_82 Copper binding proteins, plastocyanin/azurin family - - - 0.000000005972 68.0
HKD2_k127_7831392_83 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000121 61.0
HKD2_k127_7831392_84 RDD family - - - 0.00000003424 64.0
HKD2_k127_7831392_85 LytR cell envelope-related transcriptional attenuator - - - 0.000000161 65.0
HKD2_k127_7831392_86 DnaJ molecular chaperone homology domain K05516 - - 0.000003392 58.0
HKD2_k127_7831392_87 - - - - 0.000009893 50.0
HKD2_k127_7831392_88 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00002534 52.0
HKD2_k127_7831392_9 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 595.0
HKD2_k127_7831392_92 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.0008666 51.0
HKD2_k127_7960004_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 593.0
HKD2_k127_7960004_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 507.0
HKD2_k127_7960004_10 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 368.0
HKD2_k127_7960004_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 339.0
HKD2_k127_7960004_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 314.0
HKD2_k127_7960004_13 PFAM Sulfotransferase K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 301.0
HKD2_k127_7960004_14 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007898 279.0
HKD2_k127_7960004_15 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001289 278.0
HKD2_k127_7960004_16 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007636 248.0
HKD2_k127_7960004_17 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001532 239.0
HKD2_k127_7960004_18 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000002733 241.0
HKD2_k127_7960004_19 Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000002729 227.0
HKD2_k127_7960004_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 504.0
HKD2_k127_7960004_20 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000006715 223.0
HKD2_k127_7960004_21 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000172 221.0
HKD2_k127_7960004_22 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000005569 203.0
HKD2_k127_7960004_23 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000008427 197.0
HKD2_k127_7960004_24 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000004782 202.0
HKD2_k127_7960004_25 nitrogen regulatory protein P-II K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000003999 182.0
HKD2_k127_7960004_26 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000005942 179.0
HKD2_k127_7960004_27 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000002944 154.0
HKD2_k127_7960004_28 LysR substrate binding domain K19338 - - 0.0000000000000000000000000000000006367 143.0
HKD2_k127_7960004_29 HAD-superfamily hydrolase subfamily IA, variant 3 K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000742 133.0
HKD2_k127_7960004_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 461.0
HKD2_k127_7960004_31 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000584 102.0
HKD2_k127_7960004_32 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000003669 105.0
HKD2_k127_7960004_33 Thioesterase - - - 0.00000000000000000001341 107.0
HKD2_k127_7960004_34 - - - - 0.00000000000000000006942 100.0
HKD2_k127_7960004_35 Regulatory protein, FmdB family - - - 0.000000000000000005302 87.0
HKD2_k127_7960004_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000632 88.0
HKD2_k127_7960004_37 NIL - - - 0.000000000008587 68.0
HKD2_k127_7960004_38 Pfam SAF domain - - - 0.00000003774 64.0
HKD2_k127_7960004_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 392.0
HKD2_k127_7960004_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 406.0
HKD2_k127_7960004_6 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 392.0
HKD2_k127_7960004_7 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 381.0
HKD2_k127_7960004_8 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 394.0
HKD2_k127_7960004_9 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 367.0
HKD2_k127_7981034_0 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 6.11e-262 832.0
HKD2_k127_7981034_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.505e-215 679.0
HKD2_k127_7981034_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000817 175.0
HKD2_k127_7981034_11 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000003627 114.0
HKD2_k127_7981034_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000001178 76.0
HKD2_k127_7981034_13 - - - - 0.0000000004044 64.0
HKD2_k127_7981034_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 550.0
HKD2_k127_7981034_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 518.0
HKD2_k127_7981034_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
HKD2_k127_7981034_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 486.0
HKD2_k127_7981034_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 437.0
HKD2_k127_7981034_7 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000674 273.0
HKD2_k127_7981034_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000001241 226.0
HKD2_k127_7981034_9 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000005172 215.0
HKD2_k127_8033443_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.441e-284 888.0
HKD2_k127_8033443_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.719e-249 779.0
HKD2_k127_8033443_10 AMP-binding enzyme - - - 1.132e-196 633.0
HKD2_k127_8033443_11 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 587.0
HKD2_k127_8033443_12 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 561.0
HKD2_k127_8033443_13 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 546.0
HKD2_k127_8033443_14 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 551.0
HKD2_k127_8033443_15 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 537.0
HKD2_k127_8033443_16 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 512.0
HKD2_k127_8033443_17 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 507.0
HKD2_k127_8033443_18 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 465.0
HKD2_k127_8033443_19 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 456.0
HKD2_k127_8033443_2 Heavy-metal-associated domain K17686 - 3.6.3.54 1.347e-238 759.0
HKD2_k127_8033443_20 Penicillin amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 473.0
HKD2_k127_8033443_21 Peptidase S15 K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 455.0
HKD2_k127_8033443_22 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 441.0
HKD2_k127_8033443_23 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 444.0
HKD2_k127_8033443_24 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 437.0
HKD2_k127_8033443_25 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 436.0
HKD2_k127_8033443_26 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 427.0
HKD2_k127_8033443_27 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 440.0
HKD2_k127_8033443_28 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 445.0
HKD2_k127_8033443_29 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 426.0
HKD2_k127_8033443_3 Belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 1.437e-229 721.0
HKD2_k127_8033443_30 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
HKD2_k127_8033443_31 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 419.0
HKD2_k127_8033443_32 Aminotransferase class I and II K00652,K01906 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 386.0
HKD2_k127_8033443_33 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 395.0
HKD2_k127_8033443_34 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 371.0
HKD2_k127_8033443_35 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 356.0
HKD2_k127_8033443_36 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 364.0
HKD2_k127_8033443_37 COG1176 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 343.0
HKD2_k127_8033443_38 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 329.0
HKD2_k127_8033443_39 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 339.0
HKD2_k127_8033443_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 4.203e-226 709.0
HKD2_k127_8033443_40 Anion-transporting ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 344.0
HKD2_k127_8033443_41 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 334.0
HKD2_k127_8033443_42 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 315.0
HKD2_k127_8033443_43 inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 310.0
HKD2_k127_8033443_44 chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 301.0
HKD2_k127_8033443_45 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 296.0
HKD2_k127_8033443_46 COG0687 Spermidine putrescine-binding periplasmic protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 296.0
HKD2_k127_8033443_47 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
HKD2_k127_8033443_48 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001929 287.0
HKD2_k127_8033443_49 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
HKD2_k127_8033443_5 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.34e-217 683.0
HKD2_k127_8033443_50 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009662 296.0
HKD2_k127_8033443_51 Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001026 294.0
HKD2_k127_8033443_52 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 269.0
HKD2_k127_8033443_53 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006995 261.0
HKD2_k127_8033443_54 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003755 265.0
HKD2_k127_8033443_55 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000005525 254.0
HKD2_k127_8033443_56 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0008150,GO:0040007 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
HKD2_k127_8033443_57 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
HKD2_k127_8033443_58 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000006402 211.0
HKD2_k127_8033443_59 alpha beta - - - 0.00000000000000000000000000000000000000000000000000002735 203.0
HKD2_k127_8033443_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.858e-201 651.0
HKD2_k127_8033443_60 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000009759 201.0
HKD2_k127_8033443_61 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000001545 200.0
HKD2_k127_8033443_62 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000001645 181.0
HKD2_k127_8033443_63 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000005932 176.0
HKD2_k127_8033443_64 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.00000000000000000000000000000000000000000000001727 175.0
HKD2_k127_8033443_65 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000007506 168.0
HKD2_k127_8033443_66 Thioesterase - - - 0.00000000000000000000000000000000000000000003074 183.0
HKD2_k127_8033443_67 AAA domain - - - 0.0000000000000000000000000000000000000000001166 179.0
HKD2_k127_8033443_68 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000004071 170.0
HKD2_k127_8033443_69 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000005807 167.0
HKD2_k127_8033443_7 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.398e-200 629.0
HKD2_k127_8033443_70 - - - - 0.000000000000000000000000000000000000000002164 168.0
HKD2_k127_8033443_71 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000000000000000000000000000000000001193 159.0
HKD2_k127_8033443_72 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000002548 156.0
HKD2_k127_8033443_73 Protein of unknown function (DUF3151) - - - 0.00000000000000000000000000000000000002438 151.0
HKD2_k127_8033443_74 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000002407 147.0
HKD2_k127_8033443_75 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000006146 139.0
HKD2_k127_8033443_76 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.00000000000000000000000000000007581 130.0
HKD2_k127_8033443_77 Zn-ribbon protein possibly nucleic acid-binding - - - 0.00000000000000000000000000000008928 134.0
HKD2_k127_8033443_78 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000007088 135.0
HKD2_k127_8033443_79 - - - - 0.0000000000000000000000000004322 131.0
HKD2_k127_8033443_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.002e-199 634.0
HKD2_k127_8033443_80 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000001771 121.0
HKD2_k127_8033443_81 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000008866 103.0
HKD2_k127_8033443_82 cheY-homologous receiver domain - - - 0.00000000000000000000001164 109.0
HKD2_k127_8033443_83 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000001633 107.0
HKD2_k127_8033443_85 Protein of unknown function (DUF1232) - - - 0.0000000000000000001031 91.0
HKD2_k127_8033443_86 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000003802 102.0
HKD2_k127_8033443_88 Protein of unknown function (DUF2752) - - - 0.000000000002284 79.0
HKD2_k127_8033443_89 diguanylate cyclase - - - 0.000000000004437 76.0
HKD2_k127_8033443_9 Zinc-binding dehydrogenase K17829 - 1.3.1.86 5.465e-199 658.0
HKD2_k127_8033443_90 Copper chaperone PCu(A)C K09796 - - 0.000000000009871 72.0
HKD2_k127_823304_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.009e-230 745.0
HKD2_k127_823304_1 Belongs to the UPF0753 family K09822 - - 4.825e-230 740.0
HKD2_k127_823304_10 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 399.0
HKD2_k127_823304_11 Alpha/beta-hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 383.0
HKD2_k127_823304_12 PFAM transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 376.0
HKD2_k127_823304_13 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 353.0
HKD2_k127_823304_14 histidine kinase, dimerisation and phosphoacceptor region K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 335.0
HKD2_k127_823304_15 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 333.0
HKD2_k127_823304_16 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 356.0
HKD2_k127_823304_17 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 331.0
HKD2_k127_823304_18 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 320.0
HKD2_k127_823304_19 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 297.0
HKD2_k127_823304_2 Belongs to the thiolase family K00626,K00632 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 2.3.1.16,2.3.1.9 6.077e-224 700.0
HKD2_k127_823304_20 FMN-dependent dehydrogenase K00101,K15054,K16422 - 1.1.2.3,1.1.3.46,1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000922 293.0
HKD2_k127_823304_21 Product type t transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002023 248.0
HKD2_k127_823304_22 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008335 263.0
HKD2_k127_823304_23 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000435 252.0
HKD2_k127_823304_24 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
HKD2_k127_823304_25 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000007917 249.0
HKD2_k127_823304_26 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003285 244.0
HKD2_k127_823304_27 Staphylococcal nuclease homologues K01174,K01286 - 3.1.31.1,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000008939 234.0
HKD2_k127_823304_28 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000002813 228.0
HKD2_k127_823304_29 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000002317 205.0
HKD2_k127_823304_3 Conserved region in glutamate synthase K00284 - 1.4.7.1 1.99e-203 647.0
HKD2_k127_823304_30 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000004071 199.0
HKD2_k127_823304_31 Cellulose biosynthesis protein BcsQ - - - 0.00000000000000000000000000000000000000000000000006436 192.0
HKD2_k127_823304_32 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000000000000000005778 169.0
HKD2_k127_823304_33 Phosphoesterase family - - - 0.000000000000000000000000000000000000000004957 168.0
HKD2_k127_823304_34 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000006139 173.0
HKD2_k127_823304_35 pfam ammecr1 K09141 - - 0.0000000000000000000000000000000000000022 157.0
HKD2_k127_823304_36 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000134 147.0
HKD2_k127_823304_37 - - - - 0.000000000000000000000000000000002645 140.0
HKD2_k127_823304_38 Transcriptional regulator - - - 0.00000000000000000000000000000005195 134.0
HKD2_k127_823304_39 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000002149 126.0
HKD2_k127_823304_4 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 565.0
HKD2_k127_823304_40 Belongs to the peptidase S26 family - - - 0.00000000000000000000000000007636 121.0
HKD2_k127_823304_41 - - - - 0.000000000000000000000001216 110.0
HKD2_k127_823304_42 MarR family - - - 0.000000000000000000001405 103.0
HKD2_k127_823304_43 Abortive infection protein K07052 - - 0.0000000000000000003184 98.0
HKD2_k127_823304_44 Predicted membrane protein (DUF2157) - - - 0.0000000000000000005722 94.0
HKD2_k127_823304_45 - - - - 0.0000000000000000009518 90.0
HKD2_k127_823304_46 MarR family - - - 0.000000000000000004264 94.0
HKD2_k127_823304_47 - - - - 0.00000000000001908 79.0
HKD2_k127_823304_48 SnoaL-like polyketide cyclase - - - 0.000000002871 70.0
HKD2_k127_823304_5 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 515.0
HKD2_k127_823304_50 - - - - 0.00004873 56.0
HKD2_k127_823304_6 diacylglycerol O-acyltransferase K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 498.0
HKD2_k127_823304_7 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 440.0
HKD2_k127_823304_8 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 451.0
HKD2_k127_823304_9 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 424.0
HKD2_k127_8344043_0 Proteasomal ATPase OB/ID domain K13527 - - 9.827e-253 794.0
HKD2_k127_8344043_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.722e-234 735.0
HKD2_k127_8344043_10 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005455 251.0
HKD2_k127_8344043_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
HKD2_k127_8344043_12 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000006411 218.0
HKD2_k127_8344043_13 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000005509 192.0
HKD2_k127_8344043_14 WYL domain - - - 0.0000000000000000000000000000000000000000000000000008993 195.0
HKD2_k127_8344043_15 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000002053 184.0
HKD2_k127_8344043_16 WYL domain K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001055 179.0
HKD2_k127_8344043_17 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000346 168.0
HKD2_k127_8344043_18 ferredoxin K05337 - - 0.0000000000000000000000000000000000001877 141.0
HKD2_k127_8344043_19 Acetyltransferase (GNAT) family - - - 0.000000000000000000000006601 109.0
HKD2_k127_8344043_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 2.637e-233 736.0
HKD2_k127_8344043_21 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.0000000000002489 71.0
HKD2_k127_8344043_22 lipid kinase activity - - - 0.0000000000009745 81.0
HKD2_k127_8344043_23 Cytochrome C biogenesis protein K05516 - - 0.000000000002424 74.0
HKD2_k127_8344043_24 protein secretion K03116,K03117,K03646 - - 0.00000000003476 69.0
HKD2_k127_8344043_3 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.487e-231 749.0
HKD2_k127_8344043_4 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 554.0
HKD2_k127_8344043_5 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 436.0
HKD2_k127_8344043_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 302.0
HKD2_k127_8344043_7 Protein of unknown function (DUF3866) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 308.0
HKD2_k127_8344043_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 276.0
HKD2_k127_8344043_9 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
HKD2_k127_8405856_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 619.0
HKD2_k127_8405856_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 611.0
HKD2_k127_8405856_10 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 376.0
HKD2_k127_8405856_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 344.0
HKD2_k127_8405856_12 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 334.0
HKD2_k127_8405856_13 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
HKD2_k127_8405856_14 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 305.0
HKD2_k127_8405856_15 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 308.0
HKD2_k127_8405856_16 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 300.0
HKD2_k127_8405856_17 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 299.0
HKD2_k127_8405856_18 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 288.0
HKD2_k127_8405856_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002689 282.0
HKD2_k127_8405856_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 578.0
HKD2_k127_8405856_20 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
HKD2_k127_8405856_21 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005348 269.0
HKD2_k127_8405856_22 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004909 270.0
HKD2_k127_8405856_23 fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005256 265.0
HKD2_k127_8405856_24 Copper resistance protein CopC K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003697 266.0
HKD2_k127_8405856_25 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000007906 248.0
HKD2_k127_8405856_26 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
HKD2_k127_8405856_27 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002004 225.0
HKD2_k127_8405856_28 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000006801 224.0
HKD2_k127_8405856_29 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
HKD2_k127_8405856_3 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 550.0
HKD2_k127_8405856_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000008623 228.0
HKD2_k127_8405856_31 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000001964 218.0
HKD2_k127_8405856_32 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
HKD2_k127_8405856_33 ABC transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000007348 212.0
HKD2_k127_8405856_34 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000001457 199.0
HKD2_k127_8405856_35 KR domain - - - 0.00000000000000000000000000000000000000000000000000001949 197.0
HKD2_k127_8405856_36 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000002045 196.0
HKD2_k127_8405856_37 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000003327 179.0
HKD2_k127_8405856_38 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000002161 183.0
HKD2_k127_8405856_39 - - - - 0.000000000000000000000000000000000000000002713 171.0
HKD2_k127_8405856_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 535.0
HKD2_k127_8405856_40 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000008075 162.0
HKD2_k127_8405856_41 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000001287 159.0
HKD2_k127_8405856_42 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000003784 168.0
HKD2_k127_8405856_43 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000001437 160.0
HKD2_k127_8405856_44 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000001269 148.0
HKD2_k127_8405856_45 PFAM Helix-turn-helix - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002217 139.0
HKD2_k127_8405856_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000001492 129.0
HKD2_k127_8405856_47 polysaccharide deacetylase - - - 0.00000000000000000000000000001722 132.0
HKD2_k127_8405856_48 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000255 128.0
HKD2_k127_8405856_49 belongs to the Fur family K03711 - - 0.0000000000000000000000000001125 124.0
HKD2_k127_8405856_5 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 468.0
HKD2_k127_8405856_50 - - - - 0.00000000000000000000001651 108.0
HKD2_k127_8405856_51 G5 K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.00000000000000009618 87.0
HKD2_k127_8405856_52 peptidase inhibitor activity - - - 0.0000000000000001864 89.0
HKD2_k127_8405856_53 Domain of unkown function (DUF1775) - - - 0.0000000000000006537 86.0
HKD2_k127_8405856_54 Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells - - - 0.0000000000006334 76.0
HKD2_k127_8405856_56 - - - - 0.00000000000598 76.0
HKD2_k127_8405856_57 - - - - 0.000000000008076 73.0
HKD2_k127_8405856_58 Putative bacterial sensory transduction regulator - - - 0.00000000007252 72.0
HKD2_k127_8405856_59 amine dehydrogenase activity - - - 0.000000006974 66.0
HKD2_k127_8405856_6 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 466.0
HKD2_k127_8405856_60 - - - - 0.000000007619 67.0
HKD2_k127_8405856_61 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0005298 45.0
HKD2_k127_8405856_7 Cytochrome b K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 437.0
HKD2_k127_8405856_8 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 434.0
HKD2_k127_8405856_9 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 379.0
HKD2_k127_8478513_0 Belongs to the GPI family K01810 - 5.3.1.9 6.684e-238 760.0
HKD2_k127_8478513_1 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 2.348e-208 680.0
HKD2_k127_8478513_10 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000001458 217.0
HKD2_k127_8478513_11 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000005909 205.0
HKD2_k127_8478513_12 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000003668 130.0
HKD2_k127_8478513_13 Cobalt transport protein K16785 - - 0.000000000000000000000000000601 131.0
HKD2_k127_8478513_14 PFAM Prenyltransferase squalene oxidase - - - 0.00000001655 66.0
HKD2_k127_8478513_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 565.0
HKD2_k127_8478513_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 521.0
HKD2_k127_8478513_4 6-phosphogluconate dehydrogenase (Decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 498.0
HKD2_k127_8478513_5 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 402.0
HKD2_k127_8478513_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 389.0
HKD2_k127_8478513_7 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 295.0
HKD2_k127_8478513_8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000003321 262.0
HKD2_k127_8478513_9 AAA domain, putative AbiEii toxin, Type IV TA system K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000004699 246.0
HKD2_k127_8559502_0 Domain of unknown function (DUF3367) - - - 1.049e-272 887.0
HKD2_k127_8559502_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 2.873e-196 636.0
HKD2_k127_8559502_10 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 432.0
HKD2_k127_8559502_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 414.0
HKD2_k127_8559502_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 380.0
HKD2_k127_8559502_13 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 379.0
HKD2_k127_8559502_14 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
HKD2_k127_8559502_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 355.0
HKD2_k127_8559502_16 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 317.0
HKD2_k127_8559502_17 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 316.0
HKD2_k127_8559502_18 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 314.0
HKD2_k127_8559502_19 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 297.0
HKD2_k127_8559502_2 PFAM amine oxidase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 641.0
HKD2_k127_8559502_20 PFAM Inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 288.0
HKD2_k127_8559502_21 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 271.0
HKD2_k127_8559502_22 Catalyzes the synthesis of activated sulfate K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
HKD2_k127_8559502_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 262.0
HKD2_k127_8559502_24 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000006374 246.0
HKD2_k127_8559502_25 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000001013 259.0
HKD2_k127_8559502_26 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002855 230.0
HKD2_k127_8559502_27 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000001322 223.0
HKD2_k127_8559502_28 Aldolase K01628,K03077,K22130 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576 4.1.1.104,4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000000000000005423 213.0
HKD2_k127_8559502_29 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000003136 174.0
HKD2_k127_8559502_3 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 475.0
HKD2_k127_8559502_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000009053 155.0
HKD2_k127_8559502_31 PFAM Methyltransferase domain K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.00000000006032 74.0
HKD2_k127_8559502_32 - - - - 0.000000001964 59.0
HKD2_k127_8559502_33 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000003365 63.0
HKD2_k127_8559502_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 500.0
HKD2_k127_8559502_5 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 476.0
HKD2_k127_8559502_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 445.0
HKD2_k127_8559502_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 429.0
HKD2_k127_8559502_8 Oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 419.0
HKD2_k127_8559502_9 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 421.0
HKD2_k127_8666028_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1133.0
HKD2_k127_8666028_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 8.428e-196 616.0
HKD2_k127_8666028_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000281 190.0
HKD2_k127_8666028_11 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000003817 196.0
HKD2_k127_8666028_12 Glycoprotease family K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000001958 181.0
HKD2_k127_8666028_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000003586 161.0
HKD2_k127_8666028_14 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003421 158.0
HKD2_k127_8666028_15 FR47-like protein K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000000000000000000000006646 155.0
HKD2_k127_8666028_16 Alpha beta hydrolase - - - 0.000000000000000000000000000000000009016 150.0
HKD2_k127_8666028_17 NUDIX domain - - - 0.0000000000000000000000000000001847 135.0
HKD2_k127_8666028_18 MASE1 domain protein K21084 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.7.65 0.0000000000000000000000000000001954 141.0
HKD2_k127_8666028_19 tRNA threonylcarbamoyladenosine modification K06925,K07102,K07452 - 2.7.1.221 0.00000000000000000000000000001102 128.0
HKD2_k127_8666028_2 type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 566.0
HKD2_k127_8666028_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000009775 118.0
HKD2_k127_8666028_21 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000005674 82.0
HKD2_k127_8666028_22 PFAM CBS domain K07182 - - 0.0000000000000000976 88.0
HKD2_k127_8666028_23 general secretion pathway protein G K02456 - - 0.0009651 49.0
HKD2_k127_8666028_3 synthetase K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 524.0
HKD2_k127_8666028_4 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 413.0
HKD2_k127_8666028_5 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 410.0
HKD2_k127_8666028_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 395.0
HKD2_k127_8666028_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 369.0
HKD2_k127_8666028_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 341.0
HKD2_k127_8666028_9 Carbohydrate kinase K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000007359 274.0
HKD2_k127_9059121_0 Flavoprotein involved in K transport K14520 - 1.14.13.84 2.109e-308 955.0
HKD2_k127_9059121_1 hydrolase, family 3 K05349 - 3.2.1.21 1.062e-196 659.0
HKD2_k127_9059121_10 PHP domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 413.0
HKD2_k127_9059121_11 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 415.0
HKD2_k127_9059121_12 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 390.0
HKD2_k127_9059121_13 SEC-C motif K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 394.0
HKD2_k127_9059121_14 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 418.0
HKD2_k127_9059121_15 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 381.0
HKD2_k127_9059121_16 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 375.0
HKD2_k127_9059121_17 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 354.0
HKD2_k127_9059121_18 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 352.0
HKD2_k127_9059121_19 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
HKD2_k127_9059121_2 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 606.0
HKD2_k127_9059121_20 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 321.0
HKD2_k127_9059121_21 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 314.0
HKD2_k127_9059121_22 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 319.0
HKD2_k127_9059121_23 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 317.0
HKD2_k127_9059121_24 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002747 293.0
HKD2_k127_9059121_25 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000005252 271.0
HKD2_k127_9059121_26 DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009058 243.0
HKD2_k127_9059121_27 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000002347 241.0
HKD2_k127_9059121_28 Evidence 5 No homology to any previously reported sequences K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000004792 250.0
HKD2_k127_9059121_29 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000774 246.0
HKD2_k127_9059121_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 524.0
HKD2_k127_9059121_30 Thioesterase-like superfamily K10805 - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HKD2_k127_9059121_31 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000002614 225.0
HKD2_k127_9059121_32 Aldolase/RraA K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000005789 175.0
HKD2_k127_9059121_33 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000002854 183.0
HKD2_k127_9059121_34 pantothenate kinase activity K00867 - 2.7.1.33 0.000000000000000000000000000000000000000000004903 188.0
HKD2_k127_9059121_35 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000001036 165.0
HKD2_k127_9059121_36 serine threonine protein kinase K03587,K08884,K12132 - 2.7.11.1,3.4.16.4 0.00000000000000000000000000000000000000007883 166.0
HKD2_k127_9059121_37 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000001737 168.0
HKD2_k127_9059121_38 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000008914 158.0
HKD2_k127_9059121_39 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000000000001155 161.0
HKD2_k127_9059121_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 500.0
HKD2_k127_9059121_40 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000001244 142.0
HKD2_k127_9059121_41 - - - - 0.00000000000000000000000000000000004649 152.0
HKD2_k127_9059121_42 Cupin 2, conserved barrel domain protein K03490 - - 0.000000000000000000000000000000001268 134.0
HKD2_k127_9059121_43 collagen metabolic process - - - 0.0000000000000000000004367 109.0
HKD2_k127_9059121_44 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000004069 105.0
HKD2_k127_9059121_46 gluconolactonase activity K14274 - - 0.000000000002085 79.0
HKD2_k127_9059121_47 PFAM blue (type 1) copper domain protein - - - 0.00000000001266 75.0
HKD2_k127_9059121_48 PFAM YCII-related domain - - - 0.0000000001439 73.0
HKD2_k127_9059121_49 Protein of unknown function (DUF2510) - - - 0.00001187 54.0
HKD2_k127_9059121_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 504.0
HKD2_k127_9059121_50 Ureidoglycolate lyase - - - 0.00002938 53.0
HKD2_k127_9059121_51 Major facilitator Superfamily - - - 0.0009183 48.0
HKD2_k127_9059121_6 Domain of unknown function (DUF3459) K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 484.0
HKD2_k127_9059121_7 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 475.0
HKD2_k127_9059121_8 Belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 475.0
HKD2_k127_9059121_9 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 417.0
HKD2_k127_9067630_0 Domain of unknown function (DUF3367) - - - 2e-323 1050.0
HKD2_k127_9067630_1 Elongation factor G C-terminus K06207 - - 1.417e-273 867.0
HKD2_k127_9067630_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 304.0
HKD2_k127_9067630_11 Evidence 5 No homology to any previously reported sequences K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002356 287.0
HKD2_k127_9067630_12 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008556 288.0
HKD2_k127_9067630_13 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006273 252.0
HKD2_k127_9067630_14 PFAM NAD-dependent epimerase dehydratase K12453 - 1.1.1.342 0.00000000000000000000000000000000000000000000000000000000000000002515 235.0
HKD2_k127_9067630_15 Predicted membrane protein (DUF2142) - - - 0.000000000000000000000000000000000000000000000000000000000009385 228.0
HKD2_k127_9067630_16 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000001815 215.0
HKD2_k127_9067630_17 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000005653 209.0
HKD2_k127_9067630_18 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000009552 192.0
HKD2_k127_9067630_19 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000001595 202.0
HKD2_k127_9067630_2 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.807e-222 706.0
HKD2_k127_9067630_20 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000003901 163.0
HKD2_k127_9067630_21 SpoIIAA-like - - - 0.0000000000000000000000000001853 118.0
HKD2_k127_9067630_23 COG0500 SAM-dependent methyltransferases - - - 0.00000000000007306 80.0
HKD2_k127_9067630_24 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.0000000000001596 83.0
HKD2_k127_9067630_25 - - - - 0.00000000001378 74.0
HKD2_k127_9067630_26 Carboxymuconolactone decarboxylase family - - - 0.00000005252 61.0
HKD2_k127_9067630_27 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000006094 63.0
HKD2_k127_9067630_3 PFAM acyl-CoA dehydrogenase domain protein - - - 8.73e-216 694.0
HKD2_k127_9067630_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 562.0
HKD2_k127_9067630_5 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 492.0
HKD2_k127_9067630_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 468.0
HKD2_k127_9067630_7 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 447.0
HKD2_k127_9067630_8 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 411.0
HKD2_k127_9067630_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 310.0
HKD2_k127_9423318_0 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.0 1316.0
HKD2_k127_9423318_1 Arylsulfatase K01130 - 3.1.6.1 0.0 1300.0
HKD2_k127_9423318_10 Sulfatase K01130 - 3.1.6.1 2.837e-228 718.0
HKD2_k127_9423318_100 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001079 284.0
HKD2_k127_9423318_101 Type ii secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001751 301.0
HKD2_k127_9423318_102 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 280.0
HKD2_k127_9423318_103 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007273 276.0
HKD2_k127_9423318_104 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 277.0
HKD2_k127_9423318_105 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 275.0
HKD2_k127_9423318_106 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000971 270.0
HKD2_k127_9423318_107 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001039 265.0
HKD2_k127_9423318_108 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003008 267.0
HKD2_k127_9423318_109 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000003591 269.0
HKD2_k127_9423318_11 Acyl-CoA dehydrogenase, N-terminal domain - - - 3.913e-225 704.0
HKD2_k127_9423318_110 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003617 263.0
HKD2_k127_9423318_111 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009303 262.0
HKD2_k127_9423318_112 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000124 255.0
HKD2_k127_9423318_113 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003484 255.0
HKD2_k127_9423318_114 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
HKD2_k127_9423318_115 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001527 257.0
HKD2_k127_9423318_116 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001629 244.0
HKD2_k127_9423318_117 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002088 247.0
HKD2_k127_9423318_118 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006178 255.0
HKD2_k127_9423318_119 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001989 248.0
HKD2_k127_9423318_12 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 1.95e-224 717.0
HKD2_k127_9423318_120 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
HKD2_k127_9423318_121 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 238.0
HKD2_k127_9423318_122 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
HKD2_k127_9423318_123 Sulfotransferase K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000001903 237.0
HKD2_k127_9423318_124 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000004417 253.0
HKD2_k127_9423318_125 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001037 237.0
HKD2_k127_9423318_126 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000001324 233.0
HKD2_k127_9423318_127 ThiJ PfpI - - - 0.00000000000000000000000000000000000000000000000000000000000000002831 230.0
HKD2_k127_9423318_128 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008382 229.0
HKD2_k127_9423318_129 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000013 235.0
HKD2_k127_9423318_13 MMPL family K06994 - - 2.918e-201 649.0
HKD2_k127_9423318_130 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000007845 226.0
HKD2_k127_9423318_131 Type ii secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000006543 222.0
HKD2_k127_9423318_132 - - - - 0.000000000000000000000000000000000000000000000000000000000003913 233.0
HKD2_k127_9423318_133 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000183 217.0
HKD2_k127_9423318_134 Evidence 5 No homology to any previously reported sequences K13687 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000004043 216.0
HKD2_k127_9423318_135 - - - - 0.000000000000000000000000000000000000000000000000000000004389 225.0
HKD2_k127_9423318_136 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000001984 196.0
HKD2_k127_9423318_137 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000378 200.0
HKD2_k127_9423318_138 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000001239 207.0
HKD2_k127_9423318_139 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000002109 194.0
HKD2_k127_9423318_14 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 6.945e-201 647.0
HKD2_k127_9423318_140 HD domain - - - 0.000000000000000000000000000000000000000000000000002056 199.0
HKD2_k127_9423318_141 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000003171 188.0
HKD2_k127_9423318_142 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000002031 199.0
HKD2_k127_9423318_143 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000002373 187.0
HKD2_k127_9423318_144 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000004518 184.0
HKD2_k127_9423318_145 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000001505 186.0
HKD2_k127_9423318_146 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000000000000000000000000000000003985 183.0
HKD2_k127_9423318_147 NifU-like domain K07400 - - 0.0000000000000000000000000000000000000000000000005131 181.0
HKD2_k127_9423318_148 Low temperature requirement - - - 0.0000000000000000000000000000000000000000000000009165 189.0
HKD2_k127_9423318_149 KaiC - - - 0.000000000000000000000000000000000000000000000008537 185.0
HKD2_k127_9423318_15 Carboxyl transferase domain - - - 2.543e-198 645.0
HKD2_k127_9423318_150 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000002238 175.0
HKD2_k127_9423318_151 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000003341 175.0
HKD2_k127_9423318_152 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000005457 188.0
HKD2_k127_9423318_153 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000000000009684 175.0
HKD2_k127_9423318_154 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000002098 176.0
HKD2_k127_9423318_155 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000007574 190.0
HKD2_k127_9423318_156 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000304 181.0
HKD2_k127_9423318_157 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000002918 169.0
HKD2_k127_9423318_158 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000002505 164.0
HKD2_k127_9423318_159 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000002669 165.0
HKD2_k127_9423318_16 - - - - 4.219e-198 643.0
HKD2_k127_9423318_160 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000001723 162.0
HKD2_k127_9423318_161 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000004647 165.0
HKD2_k127_9423318_162 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000001963 160.0
HKD2_k127_9423318_163 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000211 154.0
HKD2_k127_9423318_164 SnoaL-like domain - - - 0.0000000000000000000000000000000000000002543 161.0
HKD2_k127_9423318_165 regulation of cellular protein catabolic process - GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000005166 154.0
HKD2_k127_9423318_166 Pilus assembly protein K02279 - - 0.0000000000000000000000000000000000000006336 158.0
HKD2_k127_9423318_167 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000007906 154.0
HKD2_k127_9423318_168 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000004654 159.0
HKD2_k127_9423318_169 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000000000000007722 154.0
HKD2_k127_9423318_17 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.301e-194 629.0
HKD2_k127_9423318_170 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000003812 160.0
HKD2_k127_9423318_171 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000004424 152.0
HKD2_k127_9423318_172 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000001775 139.0
HKD2_k127_9423318_173 GAF domain - - - 0.0000000000000000000000000000000002137 150.0
HKD2_k127_9423318_174 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002816 139.0
HKD2_k127_9423318_175 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000181 138.0
HKD2_k127_9423318_176 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000003004 149.0
HKD2_k127_9423318_177 Nitrate and nitrite sensing - - - 0.00000000000000000000000000000004997 146.0
HKD2_k127_9423318_178 Belongs to the NUDIX hydrolase family - - - 0.00000000000000000000000000000006644 135.0
HKD2_k127_9423318_179 Required for disulfide bond formation in some proteins K03611 - - 0.0000000000000000000000000000002239 131.0
HKD2_k127_9423318_18 Sulfate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 616.0
HKD2_k127_9423318_180 - - - - 0.0000000000000000000000000000006031 136.0
HKD2_k127_9423318_181 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000001801 123.0
HKD2_k127_9423318_182 Acid phosphatase homologues - - - 0.000000000000000000000000000002002 136.0
HKD2_k127_9423318_183 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000002086 139.0
HKD2_k127_9423318_184 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000002713 139.0
HKD2_k127_9423318_185 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000005971 131.0
HKD2_k127_9423318_186 ribonuclease BN K07058 - - 0.0000000000000000000000000002374 128.0
HKD2_k127_9423318_187 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000005533 124.0
HKD2_k127_9423318_188 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000003025 123.0
HKD2_k127_9423318_189 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K03215,K06969,K14292 - 2.1.1.190,2.1.1.191 0.00000000000000000000000001144 121.0
HKD2_k127_9423318_19 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 600.0
HKD2_k127_9423318_190 arsR family - - - 0.00000000000000000000000003724 111.0
HKD2_k127_9423318_191 Binds the 23S rRNA K02909 - - 0.00000000000000000000000004343 108.0
HKD2_k127_9423318_192 Protein of unknown function (DUF983) - - - 0.0000000000000000000000001451 119.0
HKD2_k127_9423318_193 DNA-binding transcription factor activity - - - 0.0000000000000000000000004738 110.0
HKD2_k127_9423318_194 thiolester hydrolase activity - - - 0.000000000000000000000004906 111.0
HKD2_k127_9423318_195 Universal stress protein family - - - 0.000000000000000000000009158 111.0
HKD2_k127_9423318_196 Polysaccharide deacetylase - - - 0.0000000000000000000004727 109.0
HKD2_k127_9423318_197 - - - - 0.000000000000000000001402 105.0
HKD2_k127_9423318_198 Redoxin - - - 0.000000000000000000001702 111.0
HKD2_k127_9423318_199 - - - - 0.000000000000000000001884 104.0
HKD2_k127_9423318_2 ABC transporter related K06147,K18894 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0015562,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030312,GO:0033036,GO:0034040,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042891,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0 1234.0
HKD2_k127_9423318_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 599.0
HKD2_k127_9423318_200 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000282 109.0
HKD2_k127_9423318_201 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000002632 106.0
HKD2_k127_9423318_202 interspecies interaction between organisms - - - 0.00000000000000000003745 102.0
HKD2_k127_9423318_203 Cupin 2, conserved barrel - - - 0.00000000000000000005042 98.0
HKD2_k127_9423318_204 protein histidine kinase activity K07642 - 2.7.13.3 0.00000000000000000007022 104.0
HKD2_k127_9423318_205 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0000000000000000001679 90.0
HKD2_k127_9423318_206 cell redox homeostasis - - - 0.000000000000000000379 98.0
HKD2_k127_9423318_207 other phosphorylase family 1 K01243 - 3.2.2.9 0.0000000000000000004638 96.0
HKD2_k127_9423318_208 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000001552 93.0
HKD2_k127_9423318_209 subunit of a heme lyase K02200 - - 0.000000000000000002992 93.0
HKD2_k127_9423318_21 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 601.0
HKD2_k127_9423318_210 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000002021 90.0
HKD2_k127_9423318_211 DUF167 - - - 0.00000000000000004406 92.0
HKD2_k127_9423318_212 response regulator - - - 0.000000000000001877 89.0
HKD2_k127_9423318_213 dienelactone hydrolase - - - 0.000000000000005373 87.0
HKD2_k127_9423318_214 - - - - 0.000000000000005789 82.0
HKD2_k127_9423318_215 TadE-like protein - - - 0.000000000000006053 81.0
HKD2_k127_9423318_216 ATP-binding protein - - - 0.0000000000001341 77.0
HKD2_k127_9423318_217 Antibiotic biosynthesis monooxygenase - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000562 70.0
HKD2_k127_9423318_218 Flp Fap pilin component K02651 - - 0.0000000001722 64.0
HKD2_k127_9423318_219 G-D-S-L family - - - 0.0000000004647 70.0
HKD2_k127_9423318_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02021,K06147,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 608.0
HKD2_k127_9423318_221 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.0000002343 58.0
HKD2_k127_9423318_222 Protein of unknown function (DUF3054) - - - 0.0000002533 60.0
HKD2_k127_9423318_223 Belongs to the glycosyl hydrolase 43 family - - - 0.000001612 51.0
HKD2_k127_9423318_224 PD-(D/E)XK nuclease superfamily K07465 - - 0.00003029 56.0
HKD2_k127_9423318_225 peptidyl-tyrosine sulfation - - - 0.00004593 55.0
HKD2_k127_9423318_226 Family of unknown function (DUF5317) - - - 0.0002387 52.0
HKD2_k127_9423318_227 AAA ATPase domain - - - 0.0008496 48.0
HKD2_k127_9423318_228 Band 7 protein - - - 0.0009427 53.0
HKD2_k127_9423318_23 Class-II DAHP synthetase family K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 585.0
HKD2_k127_9423318_24 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 581.0
HKD2_k127_9423318_25 Secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 589.0
HKD2_k127_9423318_26 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 578.0
HKD2_k127_9423318_27 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 598.0
HKD2_k127_9423318_28 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 572.0
HKD2_k127_9423318_29 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 564.0
HKD2_k127_9423318_3 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 0.0 1085.0
HKD2_k127_9423318_30 Pyridoxal-dependent decarboxylase conserved domain K01580,K01634 - 4.1.1.15,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 557.0
HKD2_k127_9423318_31 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 543.0
HKD2_k127_9423318_32 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 515.0
HKD2_k127_9423318_33 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 550.0
HKD2_k127_9423318_34 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 513.0
HKD2_k127_9423318_35 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 511.0
HKD2_k127_9423318_36 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 507.0
HKD2_k127_9423318_37 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 509.0
HKD2_k127_9423318_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 496.0
HKD2_k127_9423318_39 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 491.0
HKD2_k127_9423318_4 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 5e-324 1012.0
HKD2_k127_9423318_40 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 485.0
HKD2_k127_9423318_41 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 491.0
HKD2_k127_9423318_42 DNA primase, small subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 478.0
HKD2_k127_9423318_43 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 472.0
HKD2_k127_9423318_44 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 487.0
HKD2_k127_9423318_45 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 460.0
HKD2_k127_9423318_46 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
HKD2_k127_9423318_47 COG2015 Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 441.0
HKD2_k127_9423318_48 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 435.0
HKD2_k127_9423318_49 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 447.0
HKD2_k127_9423318_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 4.387e-284 891.0
HKD2_k127_9423318_50 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 458.0
HKD2_k127_9423318_51 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 439.0
HKD2_k127_9423318_52 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 428.0
HKD2_k127_9423318_53 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 422.0
HKD2_k127_9423318_54 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 426.0
HKD2_k127_9423318_55 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 424.0
HKD2_k127_9423318_56 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 405.0
HKD2_k127_9423318_57 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 406.0
HKD2_k127_9423318_58 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 410.0
HKD2_k127_9423318_59 anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 407.0
HKD2_k127_9423318_6 Glycosyl hydrolases family 15 - - - 1.166e-252 794.0
HKD2_k127_9423318_60 UDP binding domain K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 407.0
HKD2_k127_9423318_61 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 410.0
HKD2_k127_9423318_62 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 400.0
HKD2_k127_9423318_63 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 393.0
HKD2_k127_9423318_64 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
HKD2_k127_9423318_65 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00055 - 1.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 381.0
HKD2_k127_9423318_66 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 372.0
HKD2_k127_9423318_67 Belongs to the group II decarboxylase family K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 373.0
HKD2_k127_9423318_68 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 366.0
HKD2_k127_9423318_69 Histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 374.0
HKD2_k127_9423318_7 ABC transporter K06147 - - 3.716e-249 802.0
HKD2_k127_9423318_70 Glycosyl transferase family 21 K00752 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 383.0
HKD2_k127_9423318_71 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 376.0
HKD2_k127_9423318_72 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 357.0
HKD2_k127_9423318_73 Alcohol dehydrogenase GroES-like domain K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 351.0
HKD2_k127_9423318_74 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 345.0
HKD2_k127_9423318_75 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 340.0
HKD2_k127_9423318_76 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
HKD2_k127_9423318_77 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 339.0
HKD2_k127_9423318_78 uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 331.0
HKD2_k127_9423318_79 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 330.0
HKD2_k127_9423318_8 Sulfatase - - - 2.317e-236 772.0
HKD2_k127_9423318_80 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 332.0
HKD2_k127_9423318_81 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
HKD2_k127_9423318_82 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 317.0
HKD2_k127_9423318_83 Pfam Anion-transporting ATPase - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 315.0
HKD2_k127_9423318_84 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 330.0
HKD2_k127_9423318_85 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 317.0
HKD2_k127_9423318_86 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 310.0
HKD2_k127_9423318_87 ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 320.0
HKD2_k127_9423318_88 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 304.0
HKD2_k127_9423318_89 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 309.0
HKD2_k127_9423318_9 ABC transporter transmembrane region K06147 - - 7.151e-235 740.0
HKD2_k127_9423318_90 pilus assembly protein K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 308.0
HKD2_k127_9423318_91 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 308.0
HKD2_k127_9423318_92 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 303.0
HKD2_k127_9423318_93 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 302.0
HKD2_k127_9423318_94 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
HKD2_k127_9423318_95 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 290.0
HKD2_k127_9423318_96 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 292.0
HKD2_k127_9423318_97 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
HKD2_k127_9423318_98 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006509 292.0
HKD2_k127_9423318_99 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000966 279.0
HKD2_k127_9521107_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K22424 - 2.7.3.13 6.572e-242 783.0
HKD2_k127_9521107_1 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008155 260.0
HKD2_k127_9521107_2 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007787 252.0
HKD2_k127_9521107_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000006224 190.0
HKD2_k127_9521107_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000001214 161.0
HKD2_k127_9521107_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000003489 163.0
HKD2_k127_9521107_6 Formyl transferase - - - 0.0000000000000000000000002491 123.0
HKD2_k127_9521107_7 Unextendable partial coding region - - - 0.00000000000000000013 88.0
HKD2_k127_9521107_8 - - - - 0.00006551 49.0
HKD2_k127_9521107_9 - - - - 0.0002368 47.0
HKD2_k127_9596286_0 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 496.0
HKD2_k127_9596286_1 phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 398.0
HKD2_k127_9596286_10 Sigma-70 region 2 - - - 0.0000000000000000000000004262 118.0
HKD2_k127_9596286_12 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000001633 100.0
HKD2_k127_9596286_13 Protein of unknown function (DUF2505) - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000001378 69.0
HKD2_k127_9596286_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 385.0
HKD2_k127_9596286_3 acid phosphatase activity K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 369.0
HKD2_k127_9596286_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 327.0
HKD2_k127_9596286_5 Peptidase family M48 K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001686 268.0
HKD2_k127_9596286_6 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000004317 203.0
HKD2_k127_9596286_7 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000000003699 164.0
HKD2_k127_9596286_8 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000001942 156.0
HKD2_k127_9596286_9 Oxidoreductase family, C-terminal alpha/beta domain K00010,K16044 - 1.1.1.18,1.1.1.369,1.1.1.371 0.0000000000000000000000000000453 130.0
HKD2_k127_9721711_0 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 502.0
HKD2_k127_9721711_1 xylulose kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 486.0
HKD2_k127_9721711_10 lactoylglutathione lyase activity - - - 0.0000000000000000000000002274 116.0
HKD2_k127_9721711_11 - - - - 0.00000000000000000001106 95.0
HKD2_k127_9721711_12 COGs COG2380 conserved - - - 0.00000000000001558 74.0
HKD2_k127_9721711_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 481.0
HKD2_k127_9721711_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 436.0
HKD2_k127_9721711_4 Glycoside hydrolase, family 20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 403.0
HKD2_k127_9721711_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 338.0
HKD2_k127_9721711_6 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 334.0
HKD2_k127_9721711_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 314.0
HKD2_k127_9721711_8 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000009113 201.0
HKD2_k127_9721711_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000002324 130.0
HKD2_k127_9775419_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.44e-303 941.0
HKD2_k127_9775419_1 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 8.405e-214 675.0
HKD2_k127_9775419_10 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 320.0
HKD2_k127_9775419_11 Peptidase family M48 K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 317.0
HKD2_k127_9775419_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 301.0
HKD2_k127_9775419_13 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HKD2_k127_9775419_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 268.0
HKD2_k127_9775419_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 271.0
HKD2_k127_9775419_16 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007389 248.0
HKD2_k127_9775419_17 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
HKD2_k127_9775419_18 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000003568 196.0
HKD2_k127_9775419_19 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000002316 194.0
HKD2_k127_9775419_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00341 - 1.6.5.3 2.795e-213 682.0
HKD2_k127_9775419_20 Protein of unknown function (DUF520) K09767 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000002003 190.0
HKD2_k127_9775419_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000003787 187.0
HKD2_k127_9775419_22 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000002906 183.0
HKD2_k127_9775419_23 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000132 157.0
HKD2_k127_9775419_24 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000001061 144.0
HKD2_k127_9775419_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000002802 128.0
HKD2_k127_9775419_26 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000000000002666 136.0
HKD2_k127_9775419_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000003837 118.0
HKD2_k127_9775419_28 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008137,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0015979,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000008142 102.0
HKD2_k127_9775419_29 Ribosomal protein L33 K02913 - - 0.000000000000000001469 90.0
HKD2_k127_9775419_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 583.0
HKD2_k127_9775419_31 phosphatidylinositol transporter activity - - - 0.000000000000008656 84.0
HKD2_k127_9775419_32 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000003313 75.0
HKD2_k127_9775419_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 600.0
HKD2_k127_9775419_5 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 562.0
HKD2_k127_9775419_6 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 502.0
HKD2_k127_9775419_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 492.0
HKD2_k127_9775419_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 397.0
HKD2_k127_9775419_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 374.0
HKD2_k127_9790055_0 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.0 1200.0
HKD2_k127_9790055_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.476e-242 753.0
HKD2_k127_9790055_10 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 377.0
HKD2_k127_9790055_11 NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 365.0
HKD2_k127_9790055_12 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 353.0
HKD2_k127_9790055_13 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 348.0
HKD2_k127_9790055_14 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 342.0
HKD2_k127_9790055_15 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 337.0
HKD2_k127_9790055_16 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 345.0
HKD2_k127_9790055_17 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 319.0
HKD2_k127_9790055_18 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 294.0
HKD2_k127_9790055_19 Protein of unknown function (DUF3097) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002678 269.0
HKD2_k127_9790055_2 DNA primase, small subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 540.0
HKD2_k127_9790055_20 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000003072 246.0
HKD2_k127_9790055_21 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000004961 248.0
HKD2_k127_9790055_22 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000001231 219.0
HKD2_k127_9790055_23 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000004207 214.0
HKD2_k127_9790055_24 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000004425 216.0
HKD2_k127_9790055_25 Survival protein SurE K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000001509 216.0
HKD2_k127_9790055_26 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000001056 206.0
HKD2_k127_9790055_27 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000001096 196.0
HKD2_k127_9790055_28 MaoC like domain - - - 0.00000000000000000000000000000000000000000000001296 189.0
HKD2_k127_9790055_29 chlorophyll binding - - - 0.00000000000000000000000000000000000000000001206 190.0
HKD2_k127_9790055_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 543.0
HKD2_k127_9790055_30 Starch binding domain - - - 0.000000000000000000000000000000000000000006603 181.0
HKD2_k127_9790055_31 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000007177 144.0
HKD2_k127_9790055_33 ABC transporter (Permease) K01992 - - 0.000000000000000000000000000000002206 147.0
HKD2_k127_9790055_34 Pfam:DUF385 - - - 0.00000000000000000000000000348 119.0
HKD2_k127_9790055_35 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000001574 123.0
HKD2_k127_9790055_36 - - - - 0.00000000000000000000003576 102.0
HKD2_k127_9790055_37 PFAM glycoside hydrolase, family 18 - - - 0.00000000000000000001702 108.0
HKD2_k127_9790055_38 - - - - 0.000000000000000008302 91.0
HKD2_k127_9790055_39 PFAM FecR protein K01179,K03933 - 3.2.1.4 0.00000000000000005746 94.0
HKD2_k127_9790055_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 522.0
HKD2_k127_9790055_40 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.000000000000002492 89.0
HKD2_k127_9790055_41 Belongs to the bacterial histone-like protein family K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000004023 87.0
HKD2_k127_9790055_42 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000000002466 87.0
HKD2_k127_9790055_43 cellulase activity - - - 0.000000000003822 83.0
HKD2_k127_9790055_44 involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000485 76.0
HKD2_k127_9790055_45 - - - - 0.000003212 54.0
HKD2_k127_9790055_47 electron transfer activity K05337 - - 0.0002794 47.0
HKD2_k127_9790055_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 501.0
HKD2_k127_9790055_6 Epoxide hydrolase N terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 511.0
HKD2_k127_9790055_7 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 531.0
HKD2_k127_9790055_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 442.0
HKD2_k127_9790055_9 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 396.0