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Overview

ID MAG01829
Name HKD2_bin.91
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus JAQBQB01
Species
Assembly information
Completeness (%) 86.88
Contamination (%) 2.5
GC content (%) 67.0
N50 (bp) 35,394
Genome size (bp) 4,873,699

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3905

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10020338_0 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 419.0
HKD2_k127_10020338_1 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 377.0
HKD2_k127_10020338_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000985 259.0
HKD2_k127_10020338_3 PFAM metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
HKD2_k127_10020338_5 PrcB C-terminal - - - 0.00000000000007489 79.0
HKD2_k127_10020338_6 - - - - 0.0000000000001158 74.0
HKD2_k127_10045363_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.906e-234 735.0
HKD2_k127_10045363_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
HKD2_k127_10045363_2 Carboxypeptidase regulatory-like domain - - - 0.0000000008038 67.0
HKD2_k127_115042_0 amine dehydrogenase activity K17285 - - 1.552e-242 757.0
HKD2_k127_115042_1 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000007896 161.0
HKD2_k127_115042_2 - - - - 0.000000005777 59.0
HKD2_k127_118753_0 Putative modulator of DNA gyrase K03568 - - 3.681e-233 733.0
HKD2_k127_118753_1 Putative modulator of DNA gyrase - - - 7.391e-194 619.0
HKD2_k127_118753_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 527.0
HKD2_k127_118753_3 proteinase inhibitor I4 serpin K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
HKD2_k127_118753_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000188 143.0
HKD2_k127_118753_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000032 122.0
HKD2_k127_118753_6 - - - - 0.0000000000000000000001261 106.0
HKD2_k127_118753_7 - - - - 0.0000000000000000000008153 108.0
HKD2_k127_1279426_0 Major Facilitator Superfamily - - - 1.383e-194 622.0
HKD2_k127_1279426_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 460.0
HKD2_k127_1279426_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 322.0
HKD2_k127_1279426_3 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 304.0
HKD2_k127_1279426_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 295.0
HKD2_k127_1279426_5 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000002391 131.0
HKD2_k127_1279426_6 ATP-dependent helicase nuclease subunit A K16898 - 3.6.4.12 0.00000000000000000000001409 109.0
HKD2_k127_1279426_7 - - - - 0.0000000000000000001714 94.0
HKD2_k127_1279426_8 DoxX-like family - - - 0.000000000000000004513 93.0
HKD2_k127_1279426_9 - - - - 0.00000000002898 73.0
HKD2_k127_1283446_0 metal-dependent hydrolase with the TIM-barrel fold - - - 4.859e-299 924.0
HKD2_k127_1283446_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 606.0
HKD2_k127_1283446_2 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 493.0
HKD2_k127_1283446_3 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 353.0
HKD2_k127_1283446_4 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000000000000000000000000000000000009174 186.0
HKD2_k127_1283446_5 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000414 176.0
HKD2_k127_1283446_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000006161 160.0
HKD2_k127_1283446_7 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000002972 159.0
HKD2_k127_1283446_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000002077 142.0
HKD2_k127_1290249_0 Carboxypeptidase regulatory-like domain - - - 0.0 1399.0
HKD2_k127_1290249_1 cellulose binding - - - 0.0 1364.0
HKD2_k127_1290249_10 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 619.0
HKD2_k127_1290249_11 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 588.0
HKD2_k127_1290249_12 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 572.0
HKD2_k127_1290249_13 thymidine phosphorylase K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 576.0
HKD2_k127_1290249_14 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K14257 - 1.14.19.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 566.0
HKD2_k127_1290249_15 FMN-dependent dehydrogenase K00101,K00467 - 1.1.2.3,1.13.12.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 556.0
HKD2_k127_1290249_16 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 567.0
HKD2_k127_1290249_17 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 539.0
HKD2_k127_1290249_18 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 505.0
HKD2_k127_1290249_19 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 445.0
HKD2_k127_1290249_2 Acetyl xylan esterase (AXE1) - - - 0.0 1086.0
HKD2_k127_1290249_20 PFAM Major Facilitator Superfamily K08224 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 437.0
HKD2_k127_1290249_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 444.0
HKD2_k127_1290249_22 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 408.0
HKD2_k127_1290249_23 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 410.0
HKD2_k127_1290249_24 alginic acid biosynthetic process K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 409.0
HKD2_k127_1290249_25 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 378.0
HKD2_k127_1290249_26 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 360.0
HKD2_k127_1290249_27 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 367.0
HKD2_k127_1290249_28 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 346.0
HKD2_k127_1290249_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 342.0
HKD2_k127_1290249_3 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 2.249e-312 970.0
HKD2_k127_1290249_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 321.0
HKD2_k127_1290249_31 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 317.0
HKD2_k127_1290249_32 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 309.0
HKD2_k127_1290249_33 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HKD2_k127_1290249_34 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 298.0
HKD2_k127_1290249_35 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 300.0
HKD2_k127_1290249_36 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000104 299.0
HKD2_k127_1290249_37 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000214 228.0
HKD2_k127_1290249_38 ATPase activity K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000002353 233.0
HKD2_k127_1290249_39 nitrous oxide K19341 - - 0.00000000000000000000000000000000000000000000000000000000000002599 225.0
HKD2_k127_1290249_4 Spermine/spermidine synthase domain - - - 2.634e-275 871.0
HKD2_k127_1290249_40 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000001636 222.0
HKD2_k127_1290249_41 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006854 236.0
HKD2_k127_1290249_42 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000000000000000000000000000009611 220.0
HKD2_k127_1290249_43 - - - - 0.000000000000000000000000000000000000000000000000000000001939 212.0
HKD2_k127_1290249_44 lipoprotein involved in nitrous oxide reduction K19342 - - 0.000000000000000000000000000000000000000000000000000000002867 206.0
HKD2_k127_1290249_45 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000001334 181.0
HKD2_k127_1290249_46 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000001972 184.0
HKD2_k127_1290249_47 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000002568 173.0
HKD2_k127_1290249_48 Universal stress protein family - - - 0.00000000000000000000000000000000000000001363 169.0
HKD2_k127_1290249_49 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000001649 161.0
HKD2_k127_1290249_5 Amidase K01426 - 3.5.1.4 5.214e-247 776.0
HKD2_k127_1290249_50 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000001528 154.0
HKD2_k127_1290249_51 Glyoxalase-like domain - - - 0.000000000000000000000000000000000001179 143.0
HKD2_k127_1290249_52 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001392 134.0
HKD2_k127_1290249_53 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0000000000000000000000000000003367 129.0
HKD2_k127_1290249_54 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000003836 128.0
HKD2_k127_1290249_55 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000002387 127.0
HKD2_k127_1290249_56 Belongs to the UPF0312 family - - - 0.000000000000000000000000007624 118.0
HKD2_k127_1290249_57 NosL K19342 - - 0.000000000000000002608 96.0
HKD2_k127_1290249_58 nuclear chromosome segregation - - - 0.0000000000000001793 90.0
HKD2_k127_1290249_59 - - - - 0.000000000000007032 85.0
HKD2_k127_1290249_6 cysteine protease - - - 2.521e-235 746.0
HKD2_k127_1290249_61 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000002218 83.0
HKD2_k127_1290249_62 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000001279 74.0
HKD2_k127_1290249_63 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000001183 77.0
HKD2_k127_1290249_64 Polymer-forming cytoskeletal - - - 0.0000000000194 70.0
HKD2_k127_1290249_66 PFAM CBS domain K04767 - - 0.00003558 54.0
HKD2_k127_1290249_68 - - - - 0.0008754 49.0
HKD2_k127_1290249_7 peptidase K01415,K07386 - 3.4.24.71 1.305e-227 725.0
HKD2_k127_1290249_8 Amidase K01426 - 3.5.1.4 2.072e-216 682.0
HKD2_k127_1290249_9 Carboxypeptidase regulatory-like domain - - - 7.635e-203 675.0
HKD2_k127_1343841_0 efflux transmembrane transporter activity - - - 4.893e-213 690.0
HKD2_k127_1343841_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 595.0
HKD2_k127_1343841_10 Aldehyde dehydrogenase family K00138 - - 0.00000000000000000000000000000000000000000000000000000000000006289 216.0
HKD2_k127_1343841_11 aminotransferase K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000001239 211.0
HKD2_k127_1343841_12 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000001629 205.0
HKD2_k127_1343841_13 - - - - 0.00000000000000000000000000000000000000000000000003026 185.0
HKD2_k127_1343841_14 cobalamin-transporting ATPase activity K02014 - - 0.0000000000000000000000000000000000000000004829 181.0
HKD2_k127_1343841_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000002541 171.0
HKD2_k127_1343841_16 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000001983 153.0
HKD2_k127_1343841_17 - - - - 0.000000000000000000000000000000000000001101 163.0
HKD2_k127_1343841_18 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000000000000000000004893 134.0
HKD2_k127_1343841_19 - - - - 0.00000000000000000000000000483 119.0
HKD2_k127_1343841_2 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 485.0
HKD2_k127_1343841_20 Forkhead associated domain - - - 0.00000000000000000000003694 108.0
HKD2_k127_1343841_21 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000002971 103.0
HKD2_k127_1343841_22 - - - - 0.000000000000000001767 86.0
HKD2_k127_1343841_23 PFAM AhpC TSA family - - - 0.0000000000000003822 89.0
HKD2_k127_1343841_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 461.0
HKD2_k127_1343841_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 434.0
HKD2_k127_1343841_5 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 375.0
HKD2_k127_1343841_6 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 339.0
HKD2_k127_1343841_7 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 348.0
HKD2_k127_1343841_8 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 294.0
HKD2_k127_1343841_9 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003859 258.0
HKD2_k127_1360128_0 TonB dependent receptor - - - 0.0 1036.0
HKD2_k127_1360128_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 6.544e-254 793.0
HKD2_k127_1360128_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000008182 246.0
HKD2_k127_1360128_11 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000021 174.0
HKD2_k127_1360128_12 - - - - 0.00000000000000000000000000000006662 128.0
HKD2_k127_1360128_13 Molybdopterin oxidoreductase - - - 0.0000000000000000000000000000001497 127.0
HKD2_k127_1360128_14 hydroperoxide reductase activity K01607 - 4.1.1.44 0.0000000000000000000000002594 108.0
HKD2_k127_1360128_2 Molybdopterin oxidoreductase K00123 - 1.17.1.9 7.406e-246 770.0
HKD2_k127_1360128_3 Peptidase family M28 - - - 5.58e-230 726.0
HKD2_k127_1360128_4 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335,K18005 - 1.12.1.2,1.6.5.3 2.003e-229 734.0
HKD2_k127_1360128_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 550.0
HKD2_k127_1360128_6 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 505.0
HKD2_k127_1360128_7 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 425.0
HKD2_k127_1360128_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 425.0
HKD2_k127_1360128_9 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 370.0
HKD2_k127_1405469_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.844e-260 814.0
HKD2_k127_1405469_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.888e-257 802.0
HKD2_k127_1405469_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 488.0
HKD2_k127_1405469_11 Polysaccharide biosynthesis C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 484.0
HKD2_k127_1405469_12 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
HKD2_k127_1405469_13 endo-1,4-beta-xylanase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 452.0
HKD2_k127_1405469_14 GIY-YIG type nucleases (URI domain) K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 434.0
HKD2_k127_1405469_15 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 386.0
HKD2_k127_1405469_16 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
HKD2_k127_1405469_17 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 353.0
HKD2_k127_1405469_18 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 357.0
HKD2_k127_1405469_19 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 334.0
HKD2_k127_1405469_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.673e-240 751.0
HKD2_k127_1405469_20 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
HKD2_k127_1405469_21 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 301.0
HKD2_k127_1405469_22 lipopolysaccharide transmembrane transporter activity K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006418 276.0
HKD2_k127_1405469_23 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000002456 276.0
HKD2_k127_1405469_24 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005078 248.0
HKD2_k127_1405469_25 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000009674 226.0
HKD2_k127_1405469_26 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000004655 217.0
HKD2_k127_1405469_27 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000004977 210.0
HKD2_k127_1405469_28 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000008361 222.0
HKD2_k127_1405469_29 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000001172 187.0
HKD2_k127_1405469_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.427e-237 747.0
HKD2_k127_1405469_30 - - - - 0.000000000000000000000000000000000000000000000002587 184.0
HKD2_k127_1405469_31 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000001666 175.0
HKD2_k127_1405469_32 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000001117 167.0
HKD2_k127_1405469_33 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000001249 160.0
HKD2_k127_1405469_34 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000001367 158.0
HKD2_k127_1405469_35 - - - - 0.0000000000000000000000000000000000000002474 156.0
HKD2_k127_1405469_38 - - - - 0.0000000000000000000000000002428 121.0
HKD2_k127_1405469_39 Lysine methyltransferase - - - 0.0000000000000000000000001574 111.0
HKD2_k127_1405469_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 8.176e-219 687.0
HKD2_k127_1405469_40 transcriptional regulator - - - 0.0000000004633 66.0
HKD2_k127_1405469_5 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 9.548e-210 659.0
HKD2_k127_1405469_6 C-terminus of AA_permease K03294 - - 6.619e-205 650.0
HKD2_k127_1405469_7 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 524.0
HKD2_k127_1405469_8 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 524.0
HKD2_k127_1405469_9 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 505.0
HKD2_k127_1413541_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1052.0
HKD2_k127_1413541_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 9.488e-293 920.0
HKD2_k127_1413541_10 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 525.0
HKD2_k127_1413541_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 535.0
HKD2_k127_1413541_12 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 488.0
HKD2_k127_1413541_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 491.0
HKD2_k127_1413541_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 492.0
HKD2_k127_1413541_15 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 499.0
HKD2_k127_1413541_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 473.0
HKD2_k127_1413541_17 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 461.0
HKD2_k127_1413541_18 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 453.0
HKD2_k127_1413541_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 462.0
HKD2_k127_1413541_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 5.092e-241 764.0
HKD2_k127_1413541_20 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 408.0
HKD2_k127_1413541_21 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 401.0
HKD2_k127_1413541_22 4Fe-4S binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 389.0
HKD2_k127_1413541_23 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
HKD2_k127_1413541_24 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 352.0
HKD2_k127_1413541_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 351.0
HKD2_k127_1413541_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HKD2_k127_1413541_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 322.0
HKD2_k127_1413541_28 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD2_k127_1413541_29 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005602 279.0
HKD2_k127_1413541_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.274e-235 744.0
HKD2_k127_1413541_30 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000005974 256.0
HKD2_k127_1413541_31 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000005993 231.0
HKD2_k127_1413541_32 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000000006874 220.0
HKD2_k127_1413541_33 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000002134 227.0
HKD2_k127_1413541_34 NDK K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000001157 211.0
HKD2_k127_1413541_35 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000001773 187.0
HKD2_k127_1413541_36 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000008074 151.0
HKD2_k127_1413541_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000002068 142.0
HKD2_k127_1413541_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000006004 132.0
HKD2_k127_1413541_39 Ribosomal L32p protein family K02911 - - 0.00000000000000000000001569 105.0
HKD2_k127_1413541_4 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 3.409e-212 667.0
HKD2_k127_1413541_40 NDH shuttles electrons from NAD(P)H plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05574,K05582 - 1.6.5.3 0.00000000000000953 79.0
HKD2_k127_1413541_41 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000007774 56.0
HKD2_k127_1413541_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 2.729e-195 618.0
HKD2_k127_1413541_6 Elongator protein 3, MiaB family, Radical SAM K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 595.0
HKD2_k127_1413541_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 588.0
HKD2_k127_1413541_8 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 559.0
HKD2_k127_1413541_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 542.0
HKD2_k127_1422869_0 DALR_2 K01883 - 6.1.1.16 1.931e-218 691.0
HKD2_k127_1422869_1 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 574.0
HKD2_k127_1422869_10 - - - - 0.000000005228 63.0
HKD2_k127_1422869_12 - - - - 0.00004089 51.0
HKD2_k127_1422869_2 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 457.0
HKD2_k127_1422869_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 422.0
HKD2_k127_1422869_4 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 334.0
HKD2_k127_1422869_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 289.0
HKD2_k127_1422869_6 - - - - 0.000000000000000000000000000000000000000000000000000000000585 204.0
HKD2_k127_1422869_7 Ribosomal protein L33 K02913 - - 0.0000000000000000000000005607 106.0
HKD2_k127_1422869_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000004967 86.0
HKD2_k127_1422869_9 - - - - 0.00000000009859 69.0
HKD2_k127_1425286_0 ASPIC and UnbV - - - 0.0 1335.0
HKD2_k127_1425286_1 ASPIC and UnbV - - - 0.0 1204.0
HKD2_k127_1425286_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 516.0
HKD2_k127_1425286_11 epimerase K00491,K21572 - 1.14.14.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 491.0
HKD2_k127_1425286_12 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 439.0
HKD2_k127_1425286_13 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 417.0
HKD2_k127_1425286_14 electron transport chain K00347,K03614 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 355.0
HKD2_k127_1425286_15 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 343.0
HKD2_k127_1425286_16 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001336 265.0
HKD2_k127_1425286_17 Membrane protein involved in cytochrome C biogenesis - - - 0.00000000000000000000000000000000000000000000008811 174.0
HKD2_k127_1425286_18 Transcriptional regulator K07979 - - 0.0000000000000000000000000000000000000000000002372 171.0
HKD2_k127_1425286_19 transport - - - 0.000000000000000000000000000000000008204 141.0
HKD2_k127_1425286_2 TonB dependent receptor - - - 0.0 1133.0
HKD2_k127_1425286_20 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000002602 135.0
HKD2_k127_1425286_21 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000001825 88.0
HKD2_k127_1425286_22 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000112 58.0
HKD2_k127_1425286_3 N-Acetylmuramoyl-L-alanine amidase K01187 - 3.2.1.20 4.919e-279 874.0
HKD2_k127_1425286_4 - - - - 2.096e-266 849.0
HKD2_k127_1425286_5 geranylgeranyl reductase activity K14257 - 1.14.19.49 2.538e-230 729.0
HKD2_k127_1425286_6 asparagine synthase K01953 - 6.3.5.4 4.86e-229 715.0
HKD2_k127_1425286_7 Trehalase K01194 - 3.2.1.28 1.044e-212 676.0
HKD2_k127_1425286_8 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 610.0
HKD2_k127_1425286_9 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 592.0
HKD2_k127_1435507_0 succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 494.0
HKD2_k127_1435507_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 350.0
HKD2_k127_1435507_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000002514 250.0
HKD2_k127_1435507_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001412 236.0
HKD2_k127_1435507_4 - - - - 0.0000000000000000000000000000000000000001363 168.0
HKD2_k127_1435507_5 Periplasmic or secreted lipoprotein - - - 0.00006495 53.0
HKD2_k127_1442963_0 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 351.0
HKD2_k127_1467689_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1032.0
HKD2_k127_1467689_1 4Fe-4S dicluster domain - - - 5.924e-313 972.0
HKD2_k127_1467689_10 Selenoprotein, putative - - - 0.00000000007331 75.0
HKD2_k127_1467689_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.871e-208 662.0
HKD2_k127_1467689_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 599.0
HKD2_k127_1467689_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 557.0
HKD2_k127_1467689_5 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 404.0
HKD2_k127_1467689_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 409.0
HKD2_k127_1467689_7 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 308.0
HKD2_k127_1467689_8 SprT-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000003467 238.0
HKD2_k127_1472076_0 Peptidase family M1 domain - - - 0.0 1036.0
HKD2_k127_1472076_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 1.515e-307 962.0
HKD2_k127_1472076_10 calcium:proton antiporter activity K07300 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015085,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015368,GO:0015369,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051139,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 359.0
HKD2_k127_1472076_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
HKD2_k127_1472076_12 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 301.0
HKD2_k127_1472076_13 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 297.0
HKD2_k127_1472076_14 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
HKD2_k127_1472076_15 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001453 276.0
HKD2_k127_1472076_16 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004989 273.0
HKD2_k127_1472076_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
HKD2_k127_1472076_18 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
HKD2_k127_1472076_19 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000889 188.0
HKD2_k127_1472076_2 Prolyl oligopeptidase family - - - 1.902e-249 800.0
HKD2_k127_1472076_20 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000816 181.0
HKD2_k127_1472076_21 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000003704 175.0
HKD2_k127_1472076_22 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000002526 179.0
HKD2_k127_1472076_23 DoxX K15977 - - 0.00000000000000000000000000000000000000005311 162.0
HKD2_k127_1472076_24 - - - - 0.000000000000000000000000000000000000007121 163.0
HKD2_k127_1472076_25 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000003334 149.0
HKD2_k127_1472076_26 Wd-40 repeat - - - 0.0000000000000000000000000000608 130.0
HKD2_k127_1472076_28 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000001769 95.0
HKD2_k127_1472076_29 - K02671 - - 0.000000005748 63.0
HKD2_k127_1472076_3 GMC oxidoreductase K03333 - 1.1.3.6 7.407e-208 670.0
HKD2_k127_1472076_30 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000009377 65.0
HKD2_k127_1472076_31 PFAM Photosynthetic reaction centre cytochrome C subunit K13992 - - 0.0000002183 63.0
HKD2_k127_1472076_32 - - - - 0.000004496 55.0
HKD2_k127_1472076_33 - - - - 0.000009376 56.0
HKD2_k127_1472076_4 response to antibiotic K00573 - 2.1.1.77 1.586e-207 655.0
HKD2_k127_1472076_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 598.0
HKD2_k127_1472076_6 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 558.0
HKD2_k127_1472076_7 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 500.0
HKD2_k127_1472076_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 462.0
HKD2_k127_1472076_9 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 392.0
HKD2_k127_1512680_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 601.0
HKD2_k127_1512680_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 559.0
HKD2_k127_1512680_10 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 453.0
HKD2_k127_1512680_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 437.0
HKD2_k127_1512680_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 401.0
HKD2_k127_1512680_13 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 351.0
HKD2_k127_1512680_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 334.0
HKD2_k127_1512680_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 329.0
HKD2_k127_1512680_16 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 287.0
HKD2_k127_1512680_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 258.0
HKD2_k127_1512680_18 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000001627 186.0
HKD2_k127_1512680_19 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000002796 185.0
HKD2_k127_1512680_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 551.0
HKD2_k127_1512680_20 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000113 191.0
HKD2_k127_1512680_21 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000001929 187.0
HKD2_k127_1512680_22 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000002624 179.0
HKD2_k127_1512680_23 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000001717 149.0
HKD2_k127_1512680_24 Dodecin K09165 - - 0.0000000000000000000000005354 106.0
HKD2_k127_1512680_25 PFAM CheW domain protein K03408 - - 0.000000000000000000000001839 113.0
HKD2_k127_1512680_26 Domain of unknown function (DUF4388) - - - 0.0000000000000000001597 95.0
HKD2_k127_1512680_27 - - - - 0.000000000000007323 76.0
HKD2_k127_1512680_28 Two component signalling adaptor domain - - - 0.000000000002887 76.0
HKD2_k127_1512680_29 - - - - 0.000000000009713 77.0
HKD2_k127_1512680_3 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 552.0
HKD2_k127_1512680_30 Roadblock/LC7 domain - - - 0.00006355 52.0
HKD2_k127_1512680_31 Tetratricopeptide repeat - - - 0.00008683 54.0
HKD2_k127_1512680_32 Roadblock/LC7 domain K07131 - - 0.0002077 53.0
HKD2_k127_1512680_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 521.0
HKD2_k127_1512680_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 515.0
HKD2_k127_1512680_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 515.0
HKD2_k127_1512680_7 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 504.0
HKD2_k127_1512680_8 Bacterial dnaA protein K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 507.0
HKD2_k127_1512680_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 481.0
HKD2_k127_1539157_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 575.0
HKD2_k127_1539157_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 573.0
HKD2_k127_1539157_10 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006972 289.0
HKD2_k127_1539157_11 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
HKD2_k127_1539157_12 Aminotransferase, class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001451 261.0
HKD2_k127_1539157_13 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002383 271.0
HKD2_k127_1539157_14 ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000002857 246.0
HKD2_k127_1539157_15 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000001623 228.0
HKD2_k127_1539157_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000003165 236.0
HKD2_k127_1539157_17 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K06956 - - 0.000000000000000000000000000000000000000000000000000000000005692 234.0
HKD2_k127_1539157_18 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000007797 216.0
HKD2_k127_1539157_19 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD2_k127_1539157_2 Domain of unknown function (DUF2172) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 551.0
HKD2_k127_1539157_20 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001289 210.0
HKD2_k127_1539157_21 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000005516 198.0
HKD2_k127_1539157_22 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000001477 186.0
HKD2_k127_1539157_23 - - - - 0.0000000000000000000000000000000000000000000003569 192.0
HKD2_k127_1539157_24 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000001742 166.0
HKD2_k127_1539157_25 YCII-related domain - - - 0.00000000000000000000000000000000000000009196 153.0
HKD2_k127_1539157_26 - - - - 0.000000000000000000000000000000000002085 139.0
HKD2_k127_1539157_27 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000008746 130.0
HKD2_k127_1539157_28 chlorophyll binding K03286,K03640 - - 0.0000000000000000000000000000005631 138.0
HKD2_k127_1539157_29 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000003577 124.0
HKD2_k127_1539157_3 peptidase K01415,K07386 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 557.0
HKD2_k127_1539157_30 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000001735 101.0
HKD2_k127_1539157_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000004064 72.0
HKD2_k127_1539157_32 Domain of unknown function (DUF4412) - - - 0.00000005019 63.0
HKD2_k127_1539157_33 - - - - 0.000003515 57.0
HKD2_k127_1539157_34 lipid glycosylation K16444 - 2.4.1.310 0.00008862 53.0
HKD2_k127_1539157_35 - - - - 0.0006617 51.0
HKD2_k127_1539157_4 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 562.0
HKD2_k127_1539157_5 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 492.0
HKD2_k127_1539157_6 ABC-type antimicrobial peptide transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 503.0
HKD2_k127_1539157_7 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 430.0
HKD2_k127_1539157_8 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 370.0
HKD2_k127_1539157_9 SMART helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 318.0
HKD2_k127_1551482_0 efflux transmembrane transporter activity - - - 1.593e-295 929.0
HKD2_k127_1551482_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000009784 122.0
HKD2_k127_1551482_2 LysR substrate binding domain - - - 0.000000000000000000000000005069 120.0
HKD2_k127_1551482_3 acetyltransferase - - - 0.00000000000000000005745 99.0
HKD2_k127_1551482_4 DinB superfamily - - - 0.0000000000000000001568 89.0
HKD2_k127_1558407_0 GMC oxidoreductase - - - 2.019e-292 904.0
HKD2_k127_1558407_1 Major Facilitator Superfamily - - - 3.034e-204 646.0
HKD2_k127_1558407_10 PFAM alpha beta hydrolase fold - - - 0.00000898 54.0
HKD2_k127_1558407_3 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 410.0
HKD2_k127_1558407_4 Transcriptional regulator - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 423.0
HKD2_k127_1558407_5 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003141 297.0
HKD2_k127_1558407_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002174 263.0
HKD2_k127_1558407_7 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000001963 197.0
HKD2_k127_1558407_8 PUCC protein - - - 0.0000000000000000000000000000000000000000000004404 184.0
HKD2_k127_1558407_9 - - - - 0.0000002039 63.0
HKD2_k127_1576394_0 Carboxypeptidase regulatory-like domain - - - 0.0 1112.0
HKD2_k127_1576394_1 Protein kinase domain K12132 - 2.7.11.1 3.128e-247 800.0
HKD2_k127_1576394_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000004101 169.0
HKD2_k127_1576394_11 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000007295 124.0
HKD2_k127_1576394_13 cysteine-type peptidase activity K19224,K21471 - - 0.00000002013 63.0
HKD2_k127_1576394_14 MacB-like periplasmic core domain - - - 0.00002939 48.0
HKD2_k127_1576394_15 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00006322 51.0
HKD2_k127_1576394_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 568.0
HKD2_k127_1576394_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 569.0
HKD2_k127_1576394_4 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 581.0
HKD2_k127_1576394_5 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001049 285.0
HKD2_k127_1576394_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
HKD2_k127_1576394_7 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000007008 201.0
HKD2_k127_1576394_8 - - - - 0.000000000000000000000000000000000000000000000000000001611 198.0
HKD2_k127_1576394_9 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000001949 184.0
HKD2_k127_1593551_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 598.0
HKD2_k127_1593551_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 527.0
HKD2_k127_1593551_10 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003702 303.0
HKD2_k127_1593551_11 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001975 269.0
HKD2_k127_1593551_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000343 261.0
HKD2_k127_1593551_13 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004211 271.0
HKD2_k127_1593551_15 protein methyltransferase activity K02687 - - 0.0000000000000000000000000000000006789 141.0
HKD2_k127_1593551_16 HAD-superfamily phosphatase, subfamily IIIC - - - 0.0000000000000000000003284 109.0
HKD2_k127_1593551_17 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.0000000000000000000007121 100.0
HKD2_k127_1593551_18 O-Antigen ligase - - - 0.00000000000000000003655 104.0
HKD2_k127_1593551_2 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 516.0
HKD2_k127_1593551_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 488.0
HKD2_k127_1593551_4 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 494.0
HKD2_k127_1593551_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 362.0
HKD2_k127_1593551_6 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 355.0
HKD2_k127_1593551_7 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 337.0
HKD2_k127_1593551_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 315.0
HKD2_k127_1593551_9 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 305.0
HKD2_k127_1615103_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000005608 233.0
HKD2_k127_1615103_1 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000001318 180.0
HKD2_k127_1645867_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 547.0
HKD2_k127_1645867_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 364.0
HKD2_k127_1645867_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 325.0
HKD2_k127_1645867_3 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001713 252.0
HKD2_k127_1645867_4 - - - - 0.000000000000000000000000000000000000000000000000000000006919 218.0
HKD2_k127_1645867_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000001234 196.0
HKD2_k127_1645867_6 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000002663 162.0
HKD2_k127_1737358_0 Luciferase-like monooxygenase - - - 1.304e-194 614.0
HKD2_k127_1737358_1 MacB-like periplasmic core domain - - - 0.00000000005894 65.0
HKD2_k127_1737358_2 - - - - 0.0000000003963 63.0
HKD2_k127_1737358_3 WD40-like Beta Propeller Repeat - - - 0.000000000955 70.0
HKD2_k127_1737358_4 Esterase PHB depolymerase - - - 0.00004254 55.0
HKD2_k127_179346_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.473e-207 655.0
HKD2_k127_179346_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 539.0
HKD2_k127_179346_2 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 476.0
HKD2_k127_179346_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000339 140.0
HKD2_k127_18372_0 cellulose binding - - - 3.221e-234 759.0
HKD2_k127_18372_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 325.0
HKD2_k127_18372_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 310.0
HKD2_k127_18372_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000892 247.0
HKD2_k127_18372_4 Methyltransferase domain - - - 0.00000000000000000000000000000008956 130.0
HKD2_k127_18372_5 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000005918 80.0
HKD2_k127_1865483_0 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 391.0
HKD2_k127_1865483_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000001033 120.0
HKD2_k127_1865483_2 Cupin domain - - - 0.000000000000001999 76.0
HKD2_k127_186579_0 Fructose-bisphosphate aldolase class-II - - - 5.034e-215 676.0
HKD2_k127_186579_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 9.356e-215 683.0
HKD2_k127_186579_10 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
HKD2_k127_186579_11 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 354.0
HKD2_k127_186579_12 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 295.0
HKD2_k127_186579_13 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 301.0
HKD2_k127_186579_14 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001606 299.0
HKD2_k127_186579_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006004 267.0
HKD2_k127_186579_16 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003568 246.0
HKD2_k127_186579_17 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007144 241.0
HKD2_k127_186579_18 YjbR - - - 0.0000000000000000000000000000000000000008689 154.0
HKD2_k127_186579_19 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000006296 138.0
HKD2_k127_186579_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 2.613e-197 625.0
HKD2_k127_186579_20 YtxH-like protein - - - 0.0000000000000000000000000000004086 127.0
HKD2_k127_186579_21 - - - - 0.0000000000009652 72.0
HKD2_k127_186579_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 607.0
HKD2_k127_186579_4 Phosphoglucose isomerase K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 584.0
HKD2_k127_186579_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 557.0
HKD2_k127_186579_6 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 493.0
HKD2_k127_186579_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 480.0
HKD2_k127_186579_8 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 445.0
HKD2_k127_186579_9 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 396.0
HKD2_k127_1869863_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1364.0
HKD2_k127_1869863_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1137.0
HKD2_k127_1869863_10 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004565 286.0
HKD2_k127_1869863_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000007773 271.0
HKD2_k127_1869863_13 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000001581 171.0
HKD2_k127_1869863_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000006986 125.0
HKD2_k127_1869863_15 COGs COG5439 conserved - - - 0.0000000000000000000000001162 119.0
HKD2_k127_1869863_16 ThiF family - - - 0.000000000000000002484 101.0
HKD2_k127_1869863_17 COGs COG5439 conserved - - - 0.000000000000001029 85.0
HKD2_k127_1869863_18 Nitroreductase - - - 0.00000000008089 74.0
HKD2_k127_1869863_19 - - - - 0.00000004005 59.0
HKD2_k127_1869863_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.487e-250 790.0
HKD2_k127_1869863_20 Universal stress protein family - - - 0.000006047 57.0
HKD2_k127_1869863_21 Trypsin-like peptidase domain - - - 0.0000817 47.0
HKD2_k127_1869863_22 6-phosphogluconolactonase activity - - - 0.0001756 51.0
HKD2_k127_1869863_23 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000655 52.0
HKD2_k127_1869863_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.431e-236 736.0
HKD2_k127_1869863_4 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 1.127e-218 689.0
HKD2_k127_1869863_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 459.0
HKD2_k127_1869863_6 phosphoserine phosphatase activity K04757,K07315,K11928,K16928 GO:0000287,GO:0003674,GO:0003824,GO:0004035,GO:0005488,GO:0005515,GO:0006355,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019219,GO:0019222,GO:0030145,GO:0031323,GO:0031326,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 2.7.11.1,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 381.0
HKD2_k127_1869863_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 363.0
HKD2_k127_1869863_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 314.0
HKD2_k127_1869863_9 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 299.0
HKD2_k127_1902654_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 501.0
HKD2_k127_1902654_1 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 473.0
HKD2_k127_1902654_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 272.0
HKD2_k127_1902654_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000001081 181.0
HKD2_k127_1902654_4 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000458 174.0
HKD2_k127_1902654_5 Glycosyl transferase 4-like domain K20444 - - 0.0000000000000000000000000001626 129.0
HKD2_k127_1902654_6 PFAM Glycosyl transferases group 1 - - - 0.000000000000001612 89.0
HKD2_k127_1913061_0 Zinc carboxypeptidase - - - 8.988e-309 966.0
HKD2_k127_1913061_1 FAD binding domain K07077 - - 1.164e-300 929.0
HKD2_k127_1913061_10 PRC-barrel domain - - - 0.000001508 59.0
HKD2_k127_1913061_11 phosphorelay signal transduction system - - - 0.00001726 51.0
HKD2_k127_1913061_12 Transposase - - - 0.00002858 55.0
HKD2_k127_1913061_2 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 7.25e-282 889.0
HKD2_k127_1913061_3 cellulose binding - - - 5.838e-206 653.0
HKD2_k127_1913061_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 509.0
HKD2_k127_1913061_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 435.0
HKD2_k127_1913061_6 Cytochrome c K12263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
HKD2_k127_1913061_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 359.0
HKD2_k127_1913061_8 Matrixin - - - 0.00000000000000000000000000000000000000000000004389 179.0
HKD2_k127_1913061_9 - - - - 0.0000005571 63.0
HKD2_k127_1998077_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.296e-320 992.0
HKD2_k127_1998077_1 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 1.191e-287 912.0
HKD2_k127_1998077_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 524.0
HKD2_k127_1998077_11 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 522.0
HKD2_k127_1998077_12 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 521.0
HKD2_k127_1998077_13 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 494.0
HKD2_k127_1998077_14 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 490.0
HKD2_k127_1998077_15 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 473.0
HKD2_k127_1998077_16 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 475.0
HKD2_k127_1998077_17 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 466.0
HKD2_k127_1998077_18 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 460.0
HKD2_k127_1998077_19 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 452.0
HKD2_k127_1998077_2 Uncharacterized protein family (UPF0051) K09014 - - 7.829e-270 835.0
HKD2_k127_1998077_20 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 413.0
HKD2_k127_1998077_21 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 394.0
HKD2_k127_1998077_22 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 371.0
HKD2_k127_1998077_23 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 377.0
HKD2_k127_1998077_24 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 363.0
HKD2_k127_1998077_25 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 348.0
HKD2_k127_1998077_26 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
HKD2_k127_1998077_27 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000335 285.0
HKD2_k127_1998077_28 ATPase-coupled sulfate transmembrane transporter activity K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
HKD2_k127_1998077_29 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000791 271.0
HKD2_k127_1998077_3 TonB-dependent receptor - - - 5.326e-256 826.0
HKD2_k127_1998077_30 protein homotetramerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001352 267.0
HKD2_k127_1998077_31 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005713 265.0
HKD2_k127_1998077_32 Ndr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007044 266.0
HKD2_k127_1998077_33 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005752 258.0
HKD2_k127_1998077_34 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000003655 249.0
HKD2_k127_1998077_35 tungstate binding K15495 - - 0.0000000000000000000000000000000000000000000000000000000000000000006727 239.0
HKD2_k127_1998077_36 Domain of unknown function (DUF4403) - - - 0.000000000000000000000000000000000000000000000000000000000000000006328 255.0
HKD2_k127_1998077_37 Matrixin - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD2_k127_1998077_38 PFAM ABC transporter related K02017,K15497 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000002266 246.0
HKD2_k127_1998077_39 Uncharacterized protein conserved in bacteria (DUF2239) K09965 - - 0.000000000000000000000000000000000000000000000000000000000000000752 224.0
HKD2_k127_1998077_4 repeat protein - - - 7.783e-248 781.0
HKD2_k127_1998077_40 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000000000000000000000000001428 209.0
HKD2_k127_1998077_41 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000001701 186.0
HKD2_k127_1998077_42 TIGRFAM SUF system FeS K04488 - - 0.000000000000000000000000000000000000000000000000001971 187.0
HKD2_k127_1998077_43 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000000000000000009022 183.0
HKD2_k127_1998077_44 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000009225 183.0
HKD2_k127_1998077_45 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000002578 186.0
HKD2_k127_1998077_46 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000003385 162.0
HKD2_k127_1998077_47 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000002237 164.0
HKD2_k127_1998077_48 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000007199 157.0
HKD2_k127_1998077_49 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000001316 156.0
HKD2_k127_1998077_5 Protein kinase domain K12132 - 2.7.11.1 1.037e-213 703.0
HKD2_k127_1998077_50 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000003987 139.0
HKD2_k127_1998077_51 Surface antigen - - - 0.000000000000000000000000000000000004148 152.0
HKD2_k127_1998077_52 - - - - 0.0000000000000000000000000000000000402 143.0
HKD2_k127_1998077_53 YCII-related domain K09780 - - 0.0000000000000000000000000000000001436 136.0
HKD2_k127_1998077_54 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000001544 153.0
HKD2_k127_1998077_55 Matrixin - - - 0.00000000000000000000000000001317 128.0
HKD2_k127_1998077_56 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000004359 123.0
HKD2_k127_1998077_57 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000003884 108.0
HKD2_k127_1998077_58 Iron-sulfur cluster assembly protein - - - 0.000000000000000000005088 97.0
HKD2_k127_1998077_59 - - - - 0.00000000000000001837 92.0
HKD2_k127_1998077_6 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.652e-208 673.0
HKD2_k127_1998077_60 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000001602 88.0
HKD2_k127_1998077_62 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000005579 66.0
HKD2_k127_1998077_7 Voltage gated chloride channel - - - 4.944e-200 639.0
HKD2_k127_1998077_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 578.0
HKD2_k127_1998077_9 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 545.0
HKD2_k127_2025464_0 GMC oxidoreductase - - - 6.481e-221 705.0
HKD2_k127_2025464_1 chaperone-mediated protein folding - - - 3.755e-211 668.0
HKD2_k127_2025464_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000002927 98.0
HKD2_k127_2025464_3 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000037 90.0
HKD2_k127_2056948_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 392.0
HKD2_k127_2056948_1 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002609 280.0
HKD2_k127_2056948_2 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000001735 193.0
HKD2_k127_2056948_3 ASCH - - - 0.0000000000000000000000000001005 120.0
HKD2_k127_2056948_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000138 98.0
HKD2_k127_2098641_0 cellulose binding - - - 0.0 1196.0
HKD2_k127_2098641_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.364e-256 805.0
HKD2_k127_2098641_2 PFAM RES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 307.0
HKD2_k127_2098641_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
HKD2_k127_2098641_4 Protein of unknown function (DUF4199) - - - 0.0000000000000000000000000000000000000000000000000000007097 199.0
HKD2_k127_2098641_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD2_k127_2098641_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000001015 173.0
HKD2_k127_2098641_8 - - - - 0.00000000000000001558 93.0
HKD2_k127_2098641_9 Protein of unknown function (DUF2384) - - - 0.0000000004318 65.0
HKD2_k127_221534_0 protein related to plant photosystem II stability assembly factor - - - 2.701e-219 686.0
HKD2_k127_221534_1 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 1.128e-211 668.0
HKD2_k127_221534_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 584.0
HKD2_k127_221534_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 494.0
HKD2_k127_221534_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 435.0
HKD2_k127_221534_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000002579 194.0
HKD2_k127_221534_6 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.000000000000000000000000000000000000000000000001283 193.0
HKD2_k127_221534_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000000000002307 138.0
HKD2_k127_2265013_0 ASPIC UnbV domain protein - - - 0.0 1700.0
HKD2_k127_2265013_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 573.0
HKD2_k127_2265013_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 518.0
HKD2_k127_2265013_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 367.0
HKD2_k127_2265013_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 336.0
HKD2_k127_2265013_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 319.0
HKD2_k127_2265013_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000005198 147.0
HKD2_k127_2265013_7 HD domain - - - 0.00000000000000000000000000000000001238 146.0
HKD2_k127_2265013_8 - - - - 0.000000000000000000000000000000008492 135.0
HKD2_k127_2265013_9 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000008833 97.0
HKD2_k127_22993_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1042.0
HKD2_k127_22993_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.059e-291 904.0
HKD2_k127_22993_10 domain, Protein - - - 0.0000000001396 70.0
HKD2_k127_22993_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 8.023e-240 749.0
HKD2_k127_22993_3 TonB dependent receptor - - - 1.01e-237 765.0
HKD2_k127_22993_4 Protein kinase domain K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 452.0
HKD2_k127_22993_5 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 395.0
HKD2_k127_22993_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 286.0
HKD2_k127_22993_7 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000004899 224.0
HKD2_k127_22993_8 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000000001374 201.0
HKD2_k127_22993_9 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000009347 188.0
HKD2_k127_2318166_0 Pfam:SusD K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 456.0
HKD2_k127_2318166_1 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000176 279.0
HKD2_k127_2318166_2 transport - - - 0.00000000000000000000000000000000000000000000000000000001896 207.0
HKD2_k127_2318166_3 Amidohydrolase family - - - 0.000000000000000000000000006039 111.0
HKD2_k127_2343570_0 efflux transmembrane transporter activity - - - 1.523e-229 735.0
HKD2_k127_2343570_1 Multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 445.0
HKD2_k127_2343570_2 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005142 261.0
HKD2_k127_246148_0 MMPL family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 607.0
HKD2_k127_246148_1 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 544.0
HKD2_k127_246148_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000001481 257.0
HKD2_k127_246148_3 23S rRNA-intervening sequence protein - - - 0.000004765 50.0
HKD2_k127_2594235_0 efflux transmembrane transporter activity - - - 1.786e-305 957.0
HKD2_k127_2594235_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 508.0
HKD2_k127_2594235_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 428.0
HKD2_k127_260767_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 5.084e-271 874.0
HKD2_k127_260767_1 Protein kinase domain K12132 - 2.7.11.1 8.172e-234 738.0
HKD2_k127_260767_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 567.0
HKD2_k127_260767_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 562.0
HKD2_k127_260767_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000006231 177.0
HKD2_k127_260767_5 - - - - 0.00000000000000000000000000000000000000001714 157.0
HKD2_k127_260767_6 Protein conserved in bacteria - - - 0.0000000000000000000000000001572 123.0
HKD2_k127_260767_7 - - - - 0.0000002511 56.0
HKD2_k127_2616869_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1728.0
HKD2_k127_2616869_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1280.0
HKD2_k127_2616869_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 594.0
HKD2_k127_2616869_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 562.0
HKD2_k127_2616869_12 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 529.0
HKD2_k127_2616869_13 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 507.0
HKD2_k127_2616869_14 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 477.0
HKD2_k127_2616869_15 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 466.0
HKD2_k127_2616869_16 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 466.0
HKD2_k127_2616869_17 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 451.0
HKD2_k127_2616869_18 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 421.0
HKD2_k127_2616869_19 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 411.0
HKD2_k127_2616869_2 Phosphate acetyl/butaryl transferase K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0 1197.0
HKD2_k127_2616869_20 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 433.0
HKD2_k127_2616869_21 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 398.0
HKD2_k127_2616869_22 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 404.0
HKD2_k127_2616869_23 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 351.0
HKD2_k127_2616869_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 316.0
HKD2_k127_2616869_25 Part of the ABC transporter FtsEX involved in K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HKD2_k127_2616869_26 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 298.0
HKD2_k127_2616869_27 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000004598 256.0
HKD2_k127_2616869_28 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004126 244.0
HKD2_k127_2616869_29 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000004034 229.0
HKD2_k127_2616869_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.565e-305 949.0
HKD2_k127_2616869_30 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000007807 205.0
HKD2_k127_2616869_31 - - - - 0.000000000000000000000000000000000000000000000000000002219 196.0
HKD2_k127_2616869_32 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000008264 177.0
HKD2_k127_2616869_33 - - - - 0.000000000000000000000000000000000000000000004017 169.0
HKD2_k127_2616869_34 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000002138 168.0
HKD2_k127_2616869_35 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000039 160.0
HKD2_k127_2616869_36 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000006683 154.0
HKD2_k127_2616869_37 - - - - 0.00000000000000000000000000009519 115.0
HKD2_k127_2616869_38 BioY family K03523 - - 0.00000000000000000000000004928 124.0
HKD2_k127_2616869_39 - - - - 0.0000000000000000004725 93.0
HKD2_k127_2616869_4 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.69e-266 852.0
HKD2_k127_2616869_40 - - - - 0.0000000000009115 79.0
HKD2_k127_2616869_42 AI-2E family transporter - - - 0.000003791 59.0
HKD2_k127_2616869_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 4.486e-236 743.0
HKD2_k127_2616869_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.444e-211 670.0
HKD2_k127_2616869_7 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 632.0
HKD2_k127_2616869_8 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 612.0
HKD2_k127_2616869_9 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 604.0
HKD2_k127_2619900_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 4.705e-209 664.0
HKD2_k127_2619900_1 Gluconate K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 529.0
HKD2_k127_2619900_10 Putative restriction endonuclease - - - 0.00000000000000000001169 102.0
HKD2_k127_2619900_11 PFAM blue (type 1) copper domain protein - - - 0.0000000000000001933 85.0
HKD2_k127_2619900_13 Bacterial Ig-like domain 2 - - - 0.00000000000001341 85.0
HKD2_k127_2619900_15 Domain of unknown function (DUF4143) K07133 - - 0.00000001613 60.0
HKD2_k127_2619900_2 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 394.0
HKD2_k127_2619900_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 333.0
HKD2_k127_2619900_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 308.0
HKD2_k127_2619900_5 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000002708 239.0
HKD2_k127_2619900_6 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000001306 176.0
HKD2_k127_2619900_7 DinB superfamily - - - 0.0000000000000000000000000000000000000000001431 174.0
HKD2_k127_2619900_8 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000113 128.0
HKD2_k127_2619900_9 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.0000000000000000000000005827 121.0
HKD2_k127_2623137_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3e-323 1068.0
HKD2_k127_2623137_1 protein secretion by the type I secretion system K11085 - - 6.783e-233 750.0
HKD2_k127_2623137_2 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 529.0
HKD2_k127_2623137_3 Surface antigen K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 519.0
HKD2_k127_2623137_4 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000001869 199.0
HKD2_k127_2623137_5 Carboxypeptidase regulatory-like domain - - - 0.00000001201 69.0
HKD2_k127_2643969_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0 1058.0
HKD2_k127_2643969_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1045.0
HKD2_k127_2643969_10 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000001064 241.0
HKD2_k127_2643969_11 Globin - - - 0.0000000000000000000000000000000000000000000000004265 184.0
HKD2_k127_2643969_12 MgtC SapB transporter K07507 - - 0.000000000000000000000000000000006501 137.0
HKD2_k127_2643969_13 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000001953 133.0
HKD2_k127_2643969_14 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000002289 123.0
HKD2_k127_2643969_17 alpha-ribazole phosphatase activity - - - 0.00000293 53.0
HKD2_k127_2643969_2 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 6.873e-215 677.0
HKD2_k127_2643969_3 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 569.0
HKD2_k127_2643969_4 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 535.0
HKD2_k127_2643969_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 519.0
HKD2_k127_2643969_6 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 491.0
HKD2_k127_2643969_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 377.0
HKD2_k127_2643969_8 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
HKD2_k127_2643969_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 275.0
HKD2_k127_2650_0 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 527.0
HKD2_k127_2650_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 490.0
HKD2_k127_2650_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HKD2_k127_2650_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 438.0
HKD2_k127_2650_4 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 413.0
HKD2_k127_2650_5 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 373.0
HKD2_k127_2650_6 creatininase K01470,K22232 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005008 284.0
HKD2_k127_2650_7 - - - - 0.0000000000000000000000000002191 123.0
HKD2_k127_2675909_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1028.0
HKD2_k127_2675909_1 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 3.781e-233 756.0
HKD2_k127_2675909_11 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000005571 201.0
HKD2_k127_2675909_12 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000000000000005077 186.0
HKD2_k127_2675909_13 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000622 180.0
HKD2_k127_2675909_14 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000004665 157.0
HKD2_k127_2675909_15 DinB family - - - 0.0000000000000000000000000000000000001252 149.0
HKD2_k127_2675909_16 nUDIX hydrolase K03574,K08320 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55,3.6.1.65 0.00000000000000000000000000000007278 130.0
HKD2_k127_2675909_17 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000001124 123.0
HKD2_k127_2675909_18 - - - - 0.0000007457 62.0
HKD2_k127_2675909_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00003306 53.0
HKD2_k127_2675909_2 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 547.0
HKD2_k127_2675909_20 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00008138 53.0
HKD2_k127_2675909_3 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 528.0
HKD2_k127_2675909_4 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
HKD2_k127_2675909_5 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 471.0
HKD2_k127_2675909_6 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 438.0
HKD2_k127_2675909_7 Serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 429.0
HKD2_k127_2675909_8 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 412.0
HKD2_k127_2675909_9 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000008157 229.0
HKD2_k127_2688063_0 Carbohydrate family 9 binding domain-like - - - 2.188e-255 816.0
HKD2_k127_2688063_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 6.019e-214 672.0
HKD2_k127_2688063_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 381.0
HKD2_k127_2688063_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HKD2_k127_2688063_12 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 392.0
HKD2_k127_2688063_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 363.0
HKD2_k127_2688063_14 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 312.0
HKD2_k127_2688063_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
HKD2_k127_2688063_16 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 293.0
HKD2_k127_2688063_17 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 288.0
HKD2_k127_2688063_18 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009345 286.0
HKD2_k127_2688063_19 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
HKD2_k127_2688063_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.199e-208 666.0
HKD2_k127_2688063_20 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
HKD2_k127_2688063_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004811 253.0
HKD2_k127_2688063_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000423 239.0
HKD2_k127_2688063_23 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000004669 202.0
HKD2_k127_2688063_24 SURF1 family K14998 - - 0.00000000000000000000000000000000000000000000000000001106 212.0
HKD2_k127_2688063_25 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000003196 190.0
HKD2_k127_2688063_26 NUDIX domain - - - 0.00000000000000000000000000000000000000000004571 167.0
HKD2_k127_2688063_28 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000006939 149.0
HKD2_k127_2688063_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 614.0
HKD2_k127_2688063_30 Penicillinase repressor - - - 0.000000000000000000000000000000000953 140.0
HKD2_k127_2688063_31 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000001636 132.0
HKD2_k127_2688063_32 Rhodanese Homology Domain - - - 0.00000000000000000000000000000003453 139.0
HKD2_k127_2688063_33 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000117 119.0
HKD2_k127_2688063_34 General stress protein K06884 - - 0.00000000000000000002538 100.0
HKD2_k127_2688063_35 Domain of unknown function (DUF4383) - - - 0.0000000000000000005895 94.0
HKD2_k127_2688063_36 - - - - 0.000000000000000002067 98.0
HKD2_k127_2688063_37 Domain of unknown function (DUF4383) - - - 0.000000000000000003649 98.0
HKD2_k127_2688063_39 Heavy-metal-associated domain K07213 - - 0.000000000001358 70.0
HKD2_k127_2688063_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 570.0
HKD2_k127_2688063_40 Heavy-metal-associated domain - - - 0.000000000748 62.0
HKD2_k127_2688063_41 PBS lyase HEAT-like repeat - - - 0.00007612 53.0
HKD2_k127_2688063_5 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 557.0
HKD2_k127_2688063_6 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 514.0
HKD2_k127_2688063_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 445.0
HKD2_k127_2688063_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 432.0
HKD2_k127_2688063_9 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 406.0
HKD2_k127_2724233_0 aminopeptidase activity K07004 - - 2.051e-299 930.0
HKD2_k127_2724233_1 LVIVD repeat - - - 3.492e-290 911.0
HKD2_k127_2724233_2 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
HKD2_k127_2724233_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000002389 138.0
HKD2_k127_2724233_5 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 0.00000000000001747 72.0
HKD2_k127_2744019_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1181.0
HKD2_k127_2744019_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.242e-223 712.0
HKD2_k127_2744019_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 291.0
HKD2_k127_2744019_11 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000008118 193.0
HKD2_k127_2744019_12 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000002318 171.0
HKD2_k127_2744019_13 - - - - 0.00000000000000000000000000000000000003664 162.0
HKD2_k127_2744019_14 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000006561 162.0
HKD2_k127_2744019_15 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000002821 144.0
HKD2_k127_2744019_16 - - - - 0.000000000000000000000000000001149 136.0
HKD2_k127_2744019_17 - - - - 0.00000000000000000000000000422 125.0
HKD2_k127_2744019_19 Protein of unknown function (DUF494) K03747 - - 0.00000000000000001095 87.0
HKD2_k127_2744019_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 1.239e-220 693.0
HKD2_k127_2744019_20 Putative restriction endonuclease - - - 0.000000007223 59.0
HKD2_k127_2744019_21 - - - - 0.0000001492 64.0
HKD2_k127_2744019_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 603.0
HKD2_k127_2744019_4 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 469.0
HKD2_k127_2744019_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 488.0
HKD2_k127_2744019_6 AMIN domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 478.0
HKD2_k127_2744019_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
HKD2_k127_2744019_8 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 423.0
HKD2_k127_2744019_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 312.0
HKD2_k127_2744151_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1240.0
HKD2_k127_2744151_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.971e-312 968.0
HKD2_k127_2744151_10 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 448.0
HKD2_k127_2744151_11 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 431.0
HKD2_k127_2744151_12 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 422.0
HKD2_k127_2744151_13 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 378.0
HKD2_k127_2744151_14 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 378.0
HKD2_k127_2744151_15 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 376.0
HKD2_k127_2744151_16 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 346.0
HKD2_k127_2744151_17 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 353.0
HKD2_k127_2744151_18 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 323.0
HKD2_k127_2744151_19 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 292.0
HKD2_k127_2744151_2 Fumarase C C-terminus K01744 - 4.3.1.1 2.169e-285 887.0
HKD2_k127_2744151_20 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 293.0
HKD2_k127_2744151_21 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 271.0
HKD2_k127_2744151_22 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001503 259.0
HKD2_k127_2744151_23 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004849 260.0
HKD2_k127_2744151_24 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006222 277.0
HKD2_k127_2744151_25 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000004422 213.0
HKD2_k127_2744151_26 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000000000000000000000000000000000000000000000009463 198.0
HKD2_k127_2744151_27 negative regulation of transcription, DNA-templated - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000004973 173.0
HKD2_k127_2744151_28 - - - - 0.000000000000000000000000000000000548 136.0
HKD2_k127_2744151_29 PFAM chemotaxis sensory transducer, histidine kinase HAMP region domain protein, Cache domain protein K03406 - - 0.0000000000000000000000000000006309 141.0
HKD2_k127_2744151_3 Transport of potassium into the cell K03549 - - 2.318e-247 784.0
HKD2_k127_2744151_30 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000000002467 111.0
HKD2_k127_2744151_31 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000007379 109.0
HKD2_k127_2744151_32 DNA polymerase alpha chain like domain K02347 - - 0.000000000000001328 78.0
HKD2_k127_2744151_33 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000009549 84.0
HKD2_k127_2744151_34 - - - - 0.00000007755 59.0
HKD2_k127_2744151_35 Belongs to the UPF0337 (CsbD) family - - - 0.000001989 54.0
HKD2_k127_2744151_4 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 547.0
HKD2_k127_2744151_5 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 526.0
HKD2_k127_2744151_6 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 511.0
HKD2_k127_2744151_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 486.0
HKD2_k127_2744151_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 454.0
HKD2_k127_2744151_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 451.0
HKD2_k127_2788640_0 Sortilin, neurotensin receptor 3, - - - 0.0 1288.0
HKD2_k127_2788640_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 552.0
HKD2_k127_2788640_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 519.0
HKD2_k127_2788640_3 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 347.0
HKD2_k127_2788640_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 322.0
HKD2_k127_2788640_5 glyoxalase III activity K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000007005 172.0
HKD2_k127_2788640_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000006332 169.0
HKD2_k127_2788640_7 CarboxypepD_reg-like domain - - - 0.00000000000000000000000339 113.0
HKD2_k127_2788640_8 Serine threonine protein kinase - - - 0.000000005949 69.0
HKD2_k127_2788640_9 OsmC-like protein - - - 0.0000001868 61.0
HKD2_k127_2796237_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 466.0
HKD2_k127_2796237_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 303.0
HKD2_k127_2796237_2 Putative lumazine-binding - - - 0.0000000000000000005094 93.0
HKD2_k127_2796237_3 Nitroreductase family - - - 0.0000000000000003113 85.0
HKD2_k127_2798425_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1717.0
HKD2_k127_2798425_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1611.0
HKD2_k127_2798425_10 Fumarase C C-terminus K01744 - 4.3.1.1 3.455e-247 772.0
HKD2_k127_2798425_11 Sodium:solute symporter family - - - 6.368e-227 712.0
HKD2_k127_2798425_12 C-terminus of AA_permease K03294 - - 2.427e-221 696.0
HKD2_k127_2798425_13 UDP binding domain K13015 - 1.1.1.136 2.986e-212 667.0
HKD2_k127_2798425_14 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.869e-205 657.0
HKD2_k127_2798425_15 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.065e-204 649.0
HKD2_k127_2798425_16 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 612.0
HKD2_k127_2798425_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 594.0
HKD2_k127_2798425_18 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 597.0
HKD2_k127_2798425_19 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 580.0
HKD2_k127_2798425_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1164.0
HKD2_k127_2798425_20 Sodium:dicarboxylate symporter family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 574.0
HKD2_k127_2798425_21 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 552.0
HKD2_k127_2798425_22 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 549.0
HKD2_k127_2798425_23 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 545.0
HKD2_k127_2798425_24 PFAM Bile acid sodium symporter K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 522.0
HKD2_k127_2798425_25 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 492.0
HKD2_k127_2798425_26 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 465.0
HKD2_k127_2798425_27 Mo-molybdopterin cofactor metabolic process K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 453.0
HKD2_k127_2798425_28 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 449.0
HKD2_k127_2798425_29 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 443.0
HKD2_k127_2798425_3 TonB-dependent receptor - - - 0.0 1148.0
HKD2_k127_2798425_30 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 392.0
HKD2_k127_2798425_31 Transcriptional regulatory protein, C terminal K02483,K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 385.0
HKD2_k127_2798425_32 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 393.0
HKD2_k127_2798425_33 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 400.0
HKD2_k127_2798425_34 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 386.0
HKD2_k127_2798425_35 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 403.0
HKD2_k127_2798425_36 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 374.0
HKD2_k127_2798425_37 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HKD2_k127_2798425_38 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 336.0
HKD2_k127_2798425_39 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 346.0
HKD2_k127_2798425_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1109.0
HKD2_k127_2798425_40 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 324.0
HKD2_k127_2798425_41 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 335.0
HKD2_k127_2798425_42 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 328.0
HKD2_k127_2798425_43 FAD dependent oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 315.0
HKD2_k127_2798425_44 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 300.0
HKD2_k127_2798425_45 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003931 297.0
HKD2_k127_2798425_46 Psort location Cytoplasmic, score 8.96 K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008592 295.0
HKD2_k127_2798425_47 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
HKD2_k127_2798425_48 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
HKD2_k127_2798425_49 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 277.0
HKD2_k127_2798425_5 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1108.0
HKD2_k127_2798425_50 Outer membrane lipoprotein K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003259 261.0
HKD2_k127_2798425_51 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002208 257.0
HKD2_k127_2798425_52 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001363 253.0
HKD2_k127_2798425_53 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 247.0
HKD2_k127_2798425_54 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001271 247.0
HKD2_k127_2798425_55 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD2_k127_2798425_56 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HKD2_k127_2798425_57 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000131 225.0
HKD2_k127_2798425_58 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000002368 227.0
HKD2_k127_2798425_59 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004821 231.0
HKD2_k127_2798425_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1032.0
HKD2_k127_2798425_60 - - - - 0.000000000000000000000000000000000000000000000000000000000000003828 227.0
HKD2_k127_2798425_61 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD2_k127_2798425_62 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
HKD2_k127_2798425_63 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000002895 208.0
HKD2_k127_2798425_64 Thioredoxin-like domain K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000001444 205.0
HKD2_k127_2798425_65 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000001477 202.0
HKD2_k127_2798425_66 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HKD2_k127_2798425_67 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000001763 198.0
HKD2_k127_2798425_68 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000001032 191.0
HKD2_k127_2798425_69 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000000000000001203 189.0
HKD2_k127_2798425_7 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 6.218e-302 938.0
HKD2_k127_2798425_70 - - - - 0.00000000000000000000000000000000000000000000000001395 185.0
HKD2_k127_2798425_71 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000000000005029 172.0
HKD2_k127_2798425_72 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000000000000000000002586 169.0
HKD2_k127_2798425_73 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000000000004544 168.0
HKD2_k127_2798425_74 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000008317 171.0
HKD2_k127_2798425_75 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000005387 162.0
HKD2_k127_2798425_76 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000005288 149.0
HKD2_k127_2798425_77 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000001745 140.0
HKD2_k127_2798425_78 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000008641 127.0
HKD2_k127_2798425_79 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000008646 134.0
HKD2_k127_2798425_8 Penicillin amidase K01434 - 3.5.1.11 1.58e-291 915.0
HKD2_k127_2798425_80 - - - - 0.00000000000000000000000000000002641 127.0
HKD2_k127_2798425_81 - - - - 0.000000000000000000000000000009668 119.0
HKD2_k127_2798425_82 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000001752 120.0
HKD2_k127_2798425_84 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000002624 119.0
HKD2_k127_2798425_85 - - - - 0.00000000000000000000000017 111.0
HKD2_k127_2798425_87 peptidyl-tyrosine sulfation - - - 0.00000000000000000008282 100.0
HKD2_k127_2798425_88 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000003884 100.0
HKD2_k127_2798425_89 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000007561 96.0
HKD2_k127_2798425_9 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 6.887e-251 790.0
HKD2_k127_2798425_90 Cytochrome C assembly protein - - - 0.000000000000000001057 96.0
HKD2_k127_2798425_91 Ribosomal protein L36 K02919 - - 0.0000000000000003651 78.0
HKD2_k127_2798425_92 - - - - 0.0000002264 57.0
HKD2_k127_2855640_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 544.0
HKD2_k127_2855640_1 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 349.0
HKD2_k127_2855640_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000003287 260.0
HKD2_k127_2855640_3 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000000000000000000001421 199.0
HKD2_k127_2855640_4 Phenylacetic acid degradation B K02610 - - 0.00000000000000000000000000000000000000000000004063 176.0
HKD2_k127_2855640_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000001338 117.0
HKD2_k127_2862794_0 WD40-like Beta Propeller Repeat - - - 7.767e-321 1013.0
HKD2_k127_2862794_1 CarboxypepD_reg-like domain - - - 3.199e-311 1001.0
HKD2_k127_2862794_10 Pfam:SusD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 422.0
HKD2_k127_2862794_11 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 405.0
HKD2_k127_2862794_12 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 378.0
HKD2_k127_2862794_13 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 365.0
HKD2_k127_2862794_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 353.0
HKD2_k127_2862794_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001953 285.0
HKD2_k127_2862794_16 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007398 260.0
HKD2_k127_2862794_17 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 239.0
HKD2_k127_2862794_18 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
HKD2_k127_2862794_19 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000000000000000003234 198.0
HKD2_k127_2862794_2 Acetyl xylan esterase (AXE1) - - - 1.101e-282 887.0
HKD2_k127_2862794_20 Serine hydrolase (FSH1) - - - 0.000000000000000000000000000000000000000000000000001741 194.0
HKD2_k127_2862794_21 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009753 177.0
HKD2_k127_2862794_22 lytic transglycosylase activity K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000006401 177.0
HKD2_k127_2862794_23 RF-1 domain K15034 - - 0.0000000000000000000000000000000000000003238 155.0
HKD2_k127_2862794_24 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000008838 148.0
HKD2_k127_2862794_25 PFAM RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000001913 141.0
HKD2_k127_2862794_26 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000002832 119.0
HKD2_k127_2862794_27 - - - - 0.0000000000000000000002517 107.0
HKD2_k127_2862794_28 - - - - 0.000000000002724 74.0
HKD2_k127_2862794_29 - - - - 0.00000000001538 75.0
HKD2_k127_2862794_3 Sugar (and other) transporter K03446 - - 1.885e-231 727.0
HKD2_k127_2862794_30 Prokaryotic N-terminal methylation motif - - - 0.000000008753 69.0
HKD2_k127_2862794_4 Bacterial regulatory protein, Fis family - - - 4.357e-215 690.0
HKD2_k127_2862794_5 PAS domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 491.0
HKD2_k127_2862794_6 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 483.0
HKD2_k127_2862794_7 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 461.0
HKD2_k127_2862794_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 422.0
HKD2_k127_2862794_9 Biotin-lipoyl like K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 414.0
HKD2_k127_2867386_0 Heat shock 70 kDa protein K04043 - - 0.0 1064.0
HKD2_k127_2867386_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 8.194e-228 726.0
HKD2_k127_2867386_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005425 268.0
HKD2_k127_2867386_11 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000004471 230.0
HKD2_k127_2867386_12 CYTH - - - 0.0000000000000000000000000000000000000006404 161.0
HKD2_k127_2867386_14 - - - - 0.000003332 56.0
HKD2_k127_2867386_15 Cna B domain protein - - - 0.0001533 51.0
HKD2_k127_2867386_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 611.0
HKD2_k127_2867386_3 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 576.0
HKD2_k127_2867386_4 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 526.0
HKD2_k127_2867386_5 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 465.0
HKD2_k127_2867386_6 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 451.0
HKD2_k127_2867386_7 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 346.0
HKD2_k127_2867386_8 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 337.0
HKD2_k127_2867386_9 Cytidylate kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 312.0
HKD2_k127_2932857_0 protein histidine kinase activity K03407,K07678 - 2.7.13.3 1.448e-284 893.0
HKD2_k127_2932857_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 511.0
HKD2_k127_2932857_10 Gas vesicle protein K - - - 0.00000000000000000000000000000000000000002246 154.0
HKD2_k127_2932857_11 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000429 157.0
HKD2_k127_2932857_12 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.000000000000000000000000000000000000001053 151.0
HKD2_k127_2932857_13 - - - - 0.00000000000000000000000000000000000001122 150.0
HKD2_k127_2932857_15 - - - - 0.000000000000000000000000000000008115 134.0
HKD2_k127_2932857_17 Rieske [2Fe-2S] domain - - - 0.0000000005243 66.0
HKD2_k127_2932857_2 PFAM Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 474.0
HKD2_k127_2932857_3 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 422.0
HKD2_k127_2932857_4 Deoxynucleoside kinase K15519 - 2.7.1.74,2.7.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 344.0
HKD2_k127_2932857_5 coenzyme binding K07071 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
HKD2_k127_2932857_6 Gas vesicle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
HKD2_k127_2932857_7 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009171 268.0
HKD2_k127_2932857_8 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000009263 229.0
HKD2_k127_2932857_9 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.0000000000000000000000000000000000000000005151 158.0
HKD2_k127_3012103_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1120.0
HKD2_k127_3012103_1 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 2.2e-322 1011.0
HKD2_k127_3012103_2 TonB dependent receptor - - - 4.984e-294 935.0
HKD2_k127_3012103_3 Beta-L-arabinofuranosidase, GH127 K09955 - - 4.029e-235 758.0
HKD2_k127_3012103_4 Pfam L-fucose isomerase, C-terminal domain - - - 2.785e-211 672.0
HKD2_k127_3012103_5 RagB SusD domain protein K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 567.0
HKD2_k127_3012103_6 Tfp pilus assembly protein tip-associated adhesin - - - 0.00000000000000000000000000000000000000000000000000000000008607 225.0
HKD2_k127_3012103_7 L-ribulose-5-phosphate 4-epimerase K03077 - 5.1.3.4 0.00000000000000000000000000000000000000000000000000006064 190.0
HKD2_k127_3012103_8 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000005189 136.0
HKD2_k127_3012103_9 TonB dependent receptor - - - 0.00000000000000000000000765 108.0
HKD2_k127_303680_0 Amidohydrolase family - - - 0.0 1159.0
HKD2_k127_303680_1 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 4.089e-269 844.0
HKD2_k127_303680_10 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000000003482 199.0
HKD2_k127_303680_11 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000001155 156.0
HKD2_k127_303680_12 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000001757 97.0
HKD2_k127_303680_13 MacB-like periplasmic core domain - - - 0.00000000000000000005797 101.0
HKD2_k127_303680_2 Peptidase family M28 - - - 1.668e-239 753.0
HKD2_k127_303680_3 Peptidase family M28 - - - 9.758e-195 627.0
HKD2_k127_303680_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 595.0
HKD2_k127_303680_5 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 503.0
HKD2_k127_303680_6 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 471.0
HKD2_k127_303680_7 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 475.0
HKD2_k127_303680_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003106 297.0
HKD2_k127_303680_9 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007366 246.0
HKD2_k127_3062980_0 DEAD/H associated K03724 - - 0.0 1884.0
HKD2_k127_3062980_1 - - - - 0.0000000000000000000000000000001173 130.0
HKD2_k127_3062980_2 Protein of unknown function (DUF2723) - - - 0.000000000000000004177 89.0
HKD2_k127_3102991_0 Peptidase dimerisation domain - - - 1.648e-248 790.0
HKD2_k127_3102991_1 carbohydrate transmembrane transporter activity K05340,K06216 GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 403.0
HKD2_k127_3102991_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000001461 243.0
HKD2_k127_3102991_3 - - - - 0.00000000000000000000000000000000000000002926 158.0
HKD2_k127_3102991_4 Amidohydrolase family - - - 0.0000000000000000000000000006758 122.0
HKD2_k127_3102991_5 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000001485 111.0
HKD2_k127_3106155_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1309.0
HKD2_k127_3106155_1 Elongation factor G, domain IV K02355 - - 6.58e-321 999.0
HKD2_k127_3106155_10 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 479.0
HKD2_k127_3106155_11 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 466.0
HKD2_k127_3106155_12 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 434.0
HKD2_k127_3106155_13 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 403.0
HKD2_k127_3106155_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
HKD2_k127_3106155_15 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 319.0
HKD2_k127_3106155_16 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 312.0
HKD2_k127_3106155_17 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
HKD2_k127_3106155_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 311.0
HKD2_k127_3106155_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
HKD2_k127_3106155_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 4.55e-271 854.0
HKD2_k127_3106155_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001544 275.0
HKD2_k127_3106155_21 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002942 226.0
HKD2_k127_3106155_22 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000027 198.0
HKD2_k127_3106155_23 trehalose biosynthetic process K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000004911 192.0
HKD2_k127_3106155_24 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000001415 192.0
HKD2_k127_3106155_25 - - - - 0.00000000000000000000000000000000000000000000942 173.0
HKD2_k127_3106155_26 - - - - 0.000000000000000000000000000000002319 138.0
HKD2_k127_3106155_27 Histone deacetylase - - - 0.00000000000000000000000000001205 127.0
HKD2_k127_3106155_28 - - - - 0.0000000000000000000000000006212 120.0
HKD2_k127_3106155_29 - - - - 0.00000000000000000000000001158 119.0
HKD2_k127_3106155_3 Serine hydrolase (FSH1) - - - 2.329e-256 807.0
HKD2_k127_3106155_30 - - - - 0.0000000000000000000000001425 109.0
HKD2_k127_3106155_31 - - - - 0.0000000000000000006464 92.0
HKD2_k127_3106155_32 - - - - 0.0000000000001582 78.0
HKD2_k127_3106155_33 Acetyltransferase (GNAT) domain - - - 0.000001808 57.0
HKD2_k127_3106155_34 Protein of unknown function DUF72 - - - 0.0001754 45.0
HKD2_k127_3106155_4 N-Acyl-D-aspartate D-glutamate deacylase K01465,K06015 - 3.5.1.81,3.5.2.3 2.467e-216 686.0
HKD2_k127_3106155_5 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 8.429e-204 646.0
HKD2_k127_3106155_6 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 594.0
HKD2_k127_3106155_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 529.0
HKD2_k127_3106155_8 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 506.0
HKD2_k127_3106155_9 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 500.0
HKD2_k127_322027_0 lipopolysaccharide transport K22110 - - 0.0 1187.0
HKD2_k127_322027_1 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003625 272.0
HKD2_k127_3303883_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 597.0
HKD2_k127_3303883_1 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 532.0
HKD2_k127_3303883_2 histidine kinase HAMP region domain protein - - - 0.00000008543 63.0
HKD2_k127_3313637_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 580.0
HKD2_k127_3313637_1 Transcription factor zinc-finger - - - 0.000000000000000000000000000000000000000002542 169.0
HKD2_k127_3313637_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000001426 138.0
HKD2_k127_3313637_3 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000003402 145.0
HKD2_k127_3313637_4 PFAM Helix-turn-helix K07729 - - 0.00000000000000007705 84.0
HKD2_k127_3313637_6 Regulator of cell autolysis - - - 0.00000003191 67.0
HKD2_k127_3360200_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 475.0
HKD2_k127_3360200_1 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 332.0
HKD2_k127_3360200_2 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000000000000000000000000000000000000002057 218.0
HKD2_k127_3360200_3 Bacterial Ig-like domain 2 - - - 0.00000000000000000000000000002669 137.0
HKD2_k127_3360200_4 - - - - 0.000000000009117 75.0
HKD2_k127_3364383_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1348.0
HKD2_k127_3364383_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1137.0
HKD2_k127_3364383_10 Arginosuccinate synthase K01940 - 6.3.4.5 2.311e-207 651.0
HKD2_k127_3364383_100 - - - - 0.0000000000000000000004243 101.0
HKD2_k127_3364383_101 - - - - 0.000000000000000000001705 103.0
HKD2_k127_3364383_102 acetyltransferase - - - 0.00000000000000000231 92.0
HKD2_k127_3364383_103 Outer membrane protein beta-barrel domain - - - 0.00000000000000006043 89.0
HKD2_k127_3364383_104 - - - - 0.0000000007086 61.0
HKD2_k127_3364383_105 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000007844 62.0
HKD2_k127_3364383_106 - - - - 0.0000000009743 61.0
HKD2_k127_3364383_108 Metallo-beta-lactamase superfamily - - - 0.0000005729 58.0
HKD2_k127_3364383_109 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.000001221 61.0
HKD2_k127_3364383_11 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.856e-201 633.0
HKD2_k127_3364383_112 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0009135 49.0
HKD2_k127_3364383_12 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 2.953e-200 628.0
HKD2_k127_3364383_13 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 6.155e-199 631.0
HKD2_k127_3364383_14 Insulinase (Peptidase family M16) - - - 1.284e-198 626.0
HKD2_k127_3364383_15 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 580.0
HKD2_k127_3364383_16 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 553.0
HKD2_k127_3364383_17 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 554.0
HKD2_k127_3364383_18 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 549.0
HKD2_k127_3364383_19 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 536.0
HKD2_k127_3364383_2 CarboxypepD_reg-like domain - - - 2e-323 1033.0
HKD2_k127_3364383_20 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 541.0
HKD2_k127_3364383_21 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 526.0
HKD2_k127_3364383_22 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 523.0
HKD2_k127_3364383_23 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 510.0
HKD2_k127_3364383_24 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 509.0
HKD2_k127_3364383_25 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 496.0
HKD2_k127_3364383_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 495.0
HKD2_k127_3364383_27 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 470.0
HKD2_k127_3364383_28 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 457.0
HKD2_k127_3364383_29 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 462.0
HKD2_k127_3364383_3 Nicastrin K01301 - 3.4.17.21 2.503e-312 970.0
HKD2_k127_3364383_30 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 446.0
HKD2_k127_3364383_31 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 457.0
HKD2_k127_3364383_32 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 434.0
HKD2_k127_3364383_33 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 439.0
HKD2_k127_3364383_34 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 416.0
HKD2_k127_3364383_35 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 412.0
HKD2_k127_3364383_36 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 402.0
HKD2_k127_3364383_37 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
HKD2_k127_3364383_38 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 395.0
HKD2_k127_3364383_39 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 395.0
HKD2_k127_3364383_4 Peptidase family M1 domain - - - 2.796e-294 918.0
HKD2_k127_3364383_40 Bacterial dnaA protein helix-turn-helix domain K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 407.0
HKD2_k127_3364383_41 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
HKD2_k127_3364383_42 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 386.0
HKD2_k127_3364383_43 Replication initiator protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 387.0
HKD2_k127_3364383_44 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 366.0
HKD2_k127_3364383_45 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 374.0
HKD2_k127_3364383_46 Aldo Keto reductase K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 365.0
HKD2_k127_3364383_47 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 368.0
HKD2_k127_3364383_48 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 353.0
HKD2_k127_3364383_49 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 363.0
HKD2_k127_3364383_5 ABC transporter K06158 - - 5.437e-259 820.0
HKD2_k127_3364383_50 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 354.0
HKD2_k127_3364383_51 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 346.0
HKD2_k127_3364383_52 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 333.0
HKD2_k127_3364383_53 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
HKD2_k127_3364383_54 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
HKD2_k127_3364383_55 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 304.0
HKD2_k127_3364383_56 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 295.0
HKD2_k127_3364383_57 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001097 280.0
HKD2_k127_3364383_58 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 286.0
HKD2_k127_3364383_59 protein tyrosine kinase activity K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008275 290.0
HKD2_k127_3364383_6 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.295e-242 770.0
HKD2_k127_3364383_60 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006341 271.0
HKD2_k127_3364383_61 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003937 259.0
HKD2_k127_3364383_62 cyclic nucleotide binding K07001,K10914 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007326 256.0
HKD2_k127_3364383_63 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
HKD2_k127_3364383_64 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000393 248.0
HKD2_k127_3364383_65 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000001966 254.0
HKD2_k127_3364383_66 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002326 252.0
HKD2_k127_3364383_67 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006914 236.0
HKD2_k127_3364383_68 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000008491 245.0
HKD2_k127_3364383_69 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000000000001463 222.0
HKD2_k127_3364383_7 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 9.491e-238 741.0
HKD2_k127_3364383_70 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000282 216.0
HKD2_k127_3364383_71 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000002795 235.0
HKD2_k127_3364383_72 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
HKD2_k127_3364383_73 - - - - 0.0000000000000000000000000000000000000000000000000000000008576 210.0
HKD2_k127_3364383_74 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000001743 205.0
HKD2_k127_3364383_75 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000003941 209.0
HKD2_k127_3364383_76 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000003139 195.0
HKD2_k127_3364383_77 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.000000000000000000000000000000000000000000000002594 179.0
HKD2_k127_3364383_78 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000003051 178.0
HKD2_k127_3364383_79 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000003451 162.0
HKD2_k127_3364383_8 l-lactate permease K02550,K03303 - - 3.857e-220 696.0
HKD2_k127_3364383_80 ArsC family - - - 0.0000000000000000000000000000000000000000002977 160.0
HKD2_k127_3364383_81 - - - - 0.000000000000000000000000000000000000001507 157.0
HKD2_k127_3364383_82 - - - - 0.000000000000000000000000000000000000004508 147.0
HKD2_k127_3364383_83 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000001235 149.0
HKD2_k127_3364383_84 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000001351 150.0
HKD2_k127_3364383_85 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000002179 143.0
HKD2_k127_3364383_86 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000000000001295 156.0
HKD2_k127_3364383_87 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000001738 130.0
HKD2_k127_3364383_88 Cold shock K03704 - - 0.000000000000000000000000000000007807 129.0
HKD2_k127_3364383_89 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000002462 136.0
HKD2_k127_3364383_9 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 5.805e-220 690.0
HKD2_k127_3364383_90 Cold shock protein domain K03704 - - 0.0000000000000000000000000000003296 131.0
HKD2_k127_3364383_91 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.000000000000000000000000000001058 140.0
HKD2_k127_3364383_92 - - - - 0.000000000000000000000000000001951 122.0
HKD2_k127_3364383_94 - - - - 0.00000000000000000000000000001003 121.0
HKD2_k127_3364383_95 Cold shock K03704 - - 0.00000000000000000000000000002657 124.0
HKD2_k127_3364383_96 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000005145 123.0
HKD2_k127_3364383_97 of the alpha beta superfamily K06889 - - 0.00000000000000000000000001408 121.0
HKD2_k127_3364383_98 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000003522 106.0
HKD2_k127_3364383_99 - - - - 0.0000000000000000000001621 108.0
HKD2_k127_3375152_0 amine dehydrogenase activity K17285 - - 4.011e-242 754.0
HKD2_k127_3375152_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 589.0
HKD2_k127_3375152_10 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000001067 205.0
HKD2_k127_3375152_11 - - - - 0.00000000000000000000000000000000000000000000000000009731 197.0
HKD2_k127_3375152_12 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD2_k127_3375152_13 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.00000000000000000000000000000004402 143.0
HKD2_k127_3375152_2 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 550.0
HKD2_k127_3375152_3 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 362.0
HKD2_k127_3375152_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
HKD2_k127_3375152_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 330.0
HKD2_k127_3375152_6 metallochaperone-like domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 259.0
HKD2_k127_3375152_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006338 249.0
HKD2_k127_3375152_8 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000004063 230.0
HKD2_k127_3375152_9 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000004237 221.0
HKD2_k127_3384596_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.487e-239 745.0
HKD2_k127_3384596_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 5.888e-202 638.0
HKD2_k127_3384596_10 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 323.0
HKD2_k127_3384596_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 332.0
HKD2_k127_3384596_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
HKD2_k127_3384596_13 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
HKD2_k127_3384596_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003186 283.0
HKD2_k127_3384596_15 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001532 263.0
HKD2_k127_3384596_16 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000007401 222.0
HKD2_k127_3384596_17 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000000000000000000000004982 183.0
HKD2_k127_3384596_18 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000006952 139.0
HKD2_k127_3384596_19 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000025 119.0
HKD2_k127_3384596_2 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 4.59e-199 627.0
HKD2_k127_3384596_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.000000000000000000000006286 102.0
HKD2_k127_3384596_21 ThiS family K03636 - - 0.00003306 53.0
HKD2_k127_3384596_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 584.0
HKD2_k127_3384596_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 591.0
HKD2_k127_3384596_5 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 557.0
HKD2_k127_3384596_6 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 543.0
HKD2_k127_3384596_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 531.0
HKD2_k127_3384596_8 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 397.0
HKD2_k127_3384596_9 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 341.0
HKD2_k127_3411552_0 MacB-like periplasmic core domain - - - 0.0 1018.0
HKD2_k127_3411552_1 YHYH protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 297.0
HKD2_k127_3411552_2 Domain of unknown function (DUF305) - - - 0.000000000000000002234 89.0
HKD2_k127_3411552_3 Domain of unknown function (DUF4412) - - - 0.0000000000001082 82.0
HKD2_k127_3676385_0 Dienelactone hydrolase family - - - 2.35e-295 927.0
HKD2_k127_3676385_1 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 612.0
HKD2_k127_3676385_2 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007049 267.0
HKD2_k127_3676385_3 NUDIX hydrolase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
HKD2_k127_3676385_4 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000009428 197.0
HKD2_k127_3676385_5 DinB family - - - 0.0000000000000000000000000000000000000000000000000131 186.0
HKD2_k127_3676385_6 - - - - 0.000000000000000000000000000000000000000000004259 169.0
HKD2_k127_3676385_7 DinB family - - - 0.0000000000000000000000000000000000004809 146.0
HKD2_k127_3676385_8 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000038 84.0
HKD2_k127_3686485_0 PFAM Prenyltransferase squalene oxidase K01077,K11751 - 3.1.3.1,3.1.3.5,3.6.1.45 5.125e-226 722.0
HKD2_k127_3686485_1 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 471.0
HKD2_k127_3686485_10 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000358 247.0
HKD2_k127_3686485_11 DoxX - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
HKD2_k127_3686485_12 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000459 198.0
HKD2_k127_3686485_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000004877 192.0
HKD2_k127_3686485_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000004419 157.0
HKD2_k127_3686485_15 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000001585 138.0
HKD2_k127_3686485_16 - - - - 0.000000000000000000000001748 113.0
HKD2_k127_3686485_17 Lysin motif - - - 0.0000000000000000002962 99.0
HKD2_k127_3686485_18 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000583 74.0
HKD2_k127_3686485_19 lyase activity - - - 0.000002038 61.0
HKD2_k127_3686485_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 436.0
HKD2_k127_3686485_20 HEAT repeats - - - 0.00001072 59.0
HKD2_k127_3686485_21 - - - - 0.0004972 46.0
HKD2_k127_3686485_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 402.0
HKD2_k127_3686485_4 M61 glycyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 399.0
HKD2_k127_3686485_5 peptidase S10 serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 352.0
HKD2_k127_3686485_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003508 292.0
HKD2_k127_3686485_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
HKD2_k127_3686485_8 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001553 259.0
HKD2_k127_3686485_9 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008813 253.0
HKD2_k127_3708351_0 Domain of unknown function (DUF5118) - - - 0.0 1107.0
HKD2_k127_3708351_1 Bacterial regulatory protein, Fis family - - - 9.212e-224 706.0
HKD2_k127_3708351_10 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004782 243.0
HKD2_k127_3708351_11 - - - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
HKD2_k127_3708351_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.0000000000000000000000000000000000001244 143.0
HKD2_k127_3708351_14 Redoxin K03564 - 1.11.1.15 0.0000000003624 63.0
HKD2_k127_3708351_2 lysine biosynthetic process via aminoadipic acid - - - 3.923e-217 704.0
HKD2_k127_3708351_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 558.0
HKD2_k127_3708351_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 479.0
HKD2_k127_3708351_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 335.0
HKD2_k127_3708351_6 cyclic nucleotide binding K12132,K20074 - 2.7.11.1,3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 331.0
HKD2_k127_3708351_7 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000387 274.0
HKD2_k127_3708351_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008007 274.0
HKD2_k127_3708351_9 Bacterial protein of unknown function (DUF839) K07093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000143 278.0
HKD2_k127_3731026_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.154e-302 941.0
HKD2_k127_3731026_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.275e-202 637.0
HKD2_k127_3731026_2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 2.417e-201 645.0
HKD2_k127_3731026_3 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 460.0
HKD2_k127_3731026_4 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
HKD2_k127_3731026_5 protein conserved in bacteria - - - 0.00000000000000000000000001707 121.0
HKD2_k127_3731026_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0001524 53.0
HKD2_k127_3731026_7 Protein of unknown function (DUF2442) - - - 0.0005026 49.0
HKD2_k127_383871_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.844e-290 904.0
HKD2_k127_383871_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.708e-257 806.0
HKD2_k127_383871_10 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 427.0
HKD2_k127_383871_11 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 424.0
HKD2_k127_383871_12 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 428.0
HKD2_k127_383871_13 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 424.0
HKD2_k127_383871_14 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 424.0
HKD2_k127_383871_15 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 411.0
HKD2_k127_383871_16 Belongs to the DapA family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 360.0
HKD2_k127_383871_17 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 355.0
HKD2_k127_383871_18 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 348.0
HKD2_k127_383871_19 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
HKD2_k127_383871_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.843e-237 759.0
HKD2_k127_383871_20 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001424 272.0
HKD2_k127_383871_21 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
HKD2_k127_383871_22 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
HKD2_k127_383871_23 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 254.0
HKD2_k127_383871_24 methyltransferase K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000003653 242.0
HKD2_k127_383871_25 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004469 250.0
HKD2_k127_383871_26 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000003221 236.0
HKD2_k127_383871_27 - - - - 0.000000000000000000000000000000000000000000000000000000003131 217.0
HKD2_k127_383871_28 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HKD2_k127_383871_29 - K07112 - - 0.0000000000000000000000000000000000000000000000000000003725 202.0
HKD2_k127_383871_3 Phosphopantetheine attachment site - - - 7.025e-226 731.0
HKD2_k127_383871_30 - K07112 - - 0.0000000000000000000000000000000000000000000000000001051 192.0
HKD2_k127_383871_31 Transcriptional regulator, gntR family - - - 0.0000000000000000000000000000000000000000000000000001378 201.0
HKD2_k127_383871_32 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000005485 196.0
HKD2_k127_383871_33 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.00000000000000000000000000000000000000000002025 170.0
HKD2_k127_383871_34 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000003743 158.0
HKD2_k127_383871_35 Response regulator receiver K02477 - - 0.000000000000000000000000000000000000000005813 171.0
HKD2_k127_383871_36 nitric oxide dioxygenase activity K17247 - - 0.00000000000000000000000000000000000000004758 164.0
HKD2_k127_383871_37 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000001382 148.0
HKD2_k127_383871_38 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000003655 141.0
HKD2_k127_383871_39 Histidine kinase K11527 - 2.7.13.3 0.00000000000000000000000000000000009536 136.0
HKD2_k127_383871_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 4.337e-194 627.0
HKD2_k127_383871_40 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000001882 129.0
HKD2_k127_383871_41 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000002645 131.0
HKD2_k127_383871_43 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000001347 112.0
HKD2_k127_383871_44 peptidase - - - 0.0000000000000003111 83.0
HKD2_k127_383871_45 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.000000000000005371 89.0
HKD2_k127_383871_46 Phosphopantetheine attachment site - - - 0.00000000000001662 85.0
HKD2_k127_383871_47 - - - - 0.000000000000255 79.0
HKD2_k127_383871_5 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 561.0
HKD2_k127_383871_6 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 506.0
HKD2_k127_383871_7 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 488.0
HKD2_k127_383871_8 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 477.0
HKD2_k127_383871_9 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 474.0
HKD2_k127_3838925_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1126.0
HKD2_k127_3838925_1 Amidohydrolase family - - - 8.845e-267 831.0
HKD2_k127_3838925_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 435.0
HKD2_k127_3838925_11 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 450.0
HKD2_k127_3838925_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 433.0
HKD2_k127_3838925_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 433.0
HKD2_k127_3838925_14 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 372.0
HKD2_k127_3838925_15 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 348.0
HKD2_k127_3838925_16 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003295 274.0
HKD2_k127_3838925_17 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000008478 260.0
HKD2_k127_3838925_18 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001916 255.0
HKD2_k127_3838925_19 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
HKD2_k127_3838925_2 NAD synthase K01916 - 6.3.1.5 1.408e-259 812.0
HKD2_k127_3838925_20 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
HKD2_k127_3838925_21 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
HKD2_k127_3838925_22 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
HKD2_k127_3838925_23 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000003806 228.0
HKD2_k127_3838925_24 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000001914 168.0
HKD2_k127_3838925_25 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000006854 168.0
HKD2_k127_3838925_26 HNH nucleases - - - 0.00000000000000000000000000000000000001886 152.0
HKD2_k127_3838925_27 HNH nucleases - - - 0.00000000000000000000000000000000000004037 145.0
HKD2_k127_3838925_28 - - - - 0.00000000000000000000000000000000000005771 149.0
HKD2_k127_3838925_29 tRNA-binding protein K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000003256 136.0
HKD2_k127_3838925_3 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.298e-256 820.0
HKD2_k127_3838925_30 - - - - 0.0000000000000000000000000000004404 126.0
HKD2_k127_3838925_31 - - - - 0.00000000000000000000000000003432 118.0
HKD2_k127_3838925_32 - - - - 0.000000000000000000000001265 117.0
HKD2_k127_3838925_33 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000008157 85.0
HKD2_k127_3838925_34 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000009097 85.0
HKD2_k127_3838925_4 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 1.185e-239 759.0
HKD2_k127_3838925_5 Thiolase, C-terminal domain K00632 - 2.3.1.16 1.448e-195 624.0
HKD2_k127_3838925_6 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 584.0
HKD2_k127_3838925_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 552.0
HKD2_k127_3838925_8 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 536.0
HKD2_k127_3838925_9 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 475.0
HKD2_k127_3844492_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.0 1116.0
HKD2_k127_3844492_1 Protein kinase domain K12132 - 2.7.11.1 9.254e-252 812.0
HKD2_k127_3844492_2 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000001602 209.0
HKD2_k127_3844492_3 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000007174 184.0
HKD2_k127_3844492_4 luxR family - - - 0.000000000000000000000000000000000000000000005503 169.0
HKD2_k127_3844492_5 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000001733 133.0
HKD2_k127_3844492_6 - - - - 0.00000000000000000001225 100.0
HKD2_k127_3859760_0 PA14 domain K05349 - 3.2.1.21 0.0 1051.0
HKD2_k127_3859760_1 lysine biosynthetic process via aminoadipic acid - - - 1.045e-269 855.0
HKD2_k127_3859760_2 Peptidase family M1 domain - - - 6.522e-256 800.0
HKD2_k127_3859760_3 Alpha-L-fucosidase K01206 - 3.2.1.51 1.458e-227 715.0
HKD2_k127_3859760_4 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 610.0
HKD2_k127_3859760_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000175 242.0
HKD2_k127_3859760_6 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000001289 163.0
HKD2_k127_3859760_7 - - - - 0.000000000000000000232 91.0
HKD2_k127_3865209_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 5.571e-254 797.0
HKD2_k127_3865209_1 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000000005326 184.0
HKD2_k127_3865209_10 Periplasmic Protein - - - 0.000000563 61.0
HKD2_k127_3865209_2 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000243 166.0
HKD2_k127_3865209_3 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000000000008556 146.0
HKD2_k127_3865209_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000001134 130.0
HKD2_k127_3865209_5 Methyltransferase - - - 0.0000000000000000000000003143 112.0
HKD2_k127_3865209_7 Uncharacterized conserved protein (DUF2164) - - - 0.000000000000003859 79.0
HKD2_k127_3865209_8 Domain of unknown function (DUF378) K09779 - - 0.00000000000003265 76.0
HKD2_k127_3865209_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000002709 66.0
HKD2_k127_3871830_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0 1195.0
HKD2_k127_3871830_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1157.0
HKD2_k127_3871830_10 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 369.0
HKD2_k127_3871830_11 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 349.0
HKD2_k127_3871830_12 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 340.0
HKD2_k127_3871830_13 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 334.0
HKD2_k127_3871830_14 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 338.0
HKD2_k127_3871830_15 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 291.0
HKD2_k127_3871830_16 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000002567 265.0
HKD2_k127_3871830_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000001022 211.0
HKD2_k127_3871830_18 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000000000000006166 202.0
HKD2_k127_3871830_19 Phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000278 188.0
HKD2_k127_3871830_2 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 1.289e-293 916.0
HKD2_k127_3871830_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000002406 190.0
HKD2_k127_3871830_21 phosphorelay signal transduction system K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000002139 196.0
HKD2_k127_3871830_22 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000001611 176.0
HKD2_k127_3871830_23 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000000000004278 157.0
HKD2_k127_3871830_24 Methyltransferase - - - 0.00000000000000000000000000000000000000002067 162.0
HKD2_k127_3871830_25 - - - - 0.000000000000000000000000000000000005447 142.0
HKD2_k127_3871830_26 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000003822 128.0
HKD2_k127_3871830_27 Heat shock protein DnaJ domain protein - - - 0.000000000000000008081 98.0
HKD2_k127_3871830_29 response regulator, receiver - - - 0.00000003026 59.0
HKD2_k127_3871830_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 2.405e-260 817.0
HKD2_k127_3871830_30 SIS domain K03271 - 5.3.1.28 0.0000002746 53.0
HKD2_k127_3871830_31 - - - - 0.0001978 49.0
HKD2_k127_3871830_32 Belongs to the glycosyl hydrolase 43 family - - - 0.0003497 47.0
HKD2_k127_3871830_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 6.649e-201 641.0
HKD2_k127_3871830_5 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 554.0
HKD2_k127_3871830_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 451.0
HKD2_k127_3871830_7 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 434.0
HKD2_k127_3871830_8 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 413.0
HKD2_k127_3871830_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 379.0
HKD2_k127_3881468_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 6.684e-318 1003.0
HKD2_k127_3881468_1 GMC oxidoreductase - - - 1.235e-220 698.0
HKD2_k127_3881468_10 Globin - - - 0.0000000000000000000000000000000000000000000005454 171.0
HKD2_k127_3881468_11 SnoaL-like domain - - - 0.000000000000000000000000000001022 127.0
HKD2_k127_3881468_12 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000001256 92.0
HKD2_k127_3881468_13 alpha-L-arabinofuranosidase - - - 0.00000000000000001081 93.0
HKD2_k127_3881468_14 - - - - 0.00000000127 63.0
HKD2_k127_3881468_15 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.000003938 55.0
HKD2_k127_3881468_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 417.0
HKD2_k127_3881468_3 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 379.0
HKD2_k127_3881468_4 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 358.0
HKD2_k127_3881468_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 308.0
HKD2_k127_3881468_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 295.0
HKD2_k127_3881468_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
HKD2_k127_3881468_8 - K21429 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004782 267.0
HKD2_k127_3881468_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000001114 224.0
HKD2_k127_3888133_0 efflux transmembrane transporter activity - - - 0.0 1155.0
HKD2_k127_3888133_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 562.0
HKD2_k127_3888133_10 glyoxalase III activity - - - 0.00000000000000000000000000000003343 132.0
HKD2_k127_3888133_11 PFAM amidohydrolase - - - 0.0000007245 51.0
HKD2_k127_3888133_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 408.0
HKD2_k127_3888133_3 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 398.0
HKD2_k127_3888133_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 309.0
HKD2_k127_3888133_5 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003094 294.0
HKD2_k127_3888133_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000006574 191.0
HKD2_k127_3888133_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000001216 195.0
HKD2_k127_3888133_8 Histidine kinase - - - 0.0000000000000000000000000000000000005634 158.0
HKD2_k127_3888133_9 - - - - 0.0000000000000000000000000000000002386 139.0
HKD2_k127_3895050_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 334.0
HKD2_k127_3895050_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 304.0
HKD2_k127_3895050_2 transferase activity, transferring glycosyl groups K09691 - - 0.00000000000000000000000000000000000000000000001002 184.0
HKD2_k127_3902786_0 Carbohydrate family 9 binding domain-like - - - 0.0 1364.0
HKD2_k127_3902786_1 Amidase K02433 - 6.3.5.6,6.3.5.7 4.387e-300 936.0
HKD2_k127_3902786_10 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000001797 170.0
HKD2_k127_3902786_11 WxcM-like, C-terminal - - - 0.0000000000000000000000000000000963 128.0
HKD2_k127_3902786_12 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000001761 89.0
HKD2_k127_3902786_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 524.0
HKD2_k127_3902786_3 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 394.0
HKD2_k127_3902786_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003146 282.0
HKD2_k127_3902786_5 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008563 268.0
HKD2_k127_3902786_6 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001954 255.0
HKD2_k127_3902786_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006206 238.0
HKD2_k127_3902786_8 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000001253 215.0
HKD2_k127_3902786_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000003261 163.0
HKD2_k127_3966540_0 MMPL family K03296 - - 0.0 1167.0
HKD2_k127_3966540_1 TonB dependent receptor - - - 2.033e-315 998.0
HKD2_k127_3966540_10 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 344.0
HKD2_k127_3966540_11 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 328.0
HKD2_k127_3966540_12 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004941 285.0
HKD2_k127_3966540_13 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003099 284.0
HKD2_k127_3966540_14 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
HKD2_k127_3966540_15 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 268.0
HKD2_k127_3966540_16 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000001094 251.0
HKD2_k127_3966540_17 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000399 218.0
HKD2_k127_3966540_18 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000001822 210.0
HKD2_k127_3966540_19 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000006415 211.0
HKD2_k127_3966540_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 576.0
HKD2_k127_3966540_20 virion core protein, lumpy skin disease virus - - - 0.0000000000000000000000000000000000000000000000000000001091 202.0
HKD2_k127_3966540_21 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000009882 194.0
HKD2_k127_3966540_22 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000008096 196.0
HKD2_k127_3966540_23 - - - - 0.0000000000000000000000000000000000000000000001446 188.0
HKD2_k127_3966540_24 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000004495 170.0
HKD2_k127_3966540_25 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000002014 169.0
HKD2_k127_3966540_26 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000005021 165.0
HKD2_k127_3966540_28 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000002125 145.0
HKD2_k127_3966540_29 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000006608 145.0
HKD2_k127_3966540_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 500.0
HKD2_k127_3966540_30 Tellurite resistance protein TerB - - - 0.000000000000000000000000003339 116.0
HKD2_k127_3966540_31 - - - - 0.00000000000000000003039 93.0
HKD2_k127_3966540_32 Type II secretion system protein K K02460 - - 0.000000000000000001906 100.0
HKD2_k127_3966540_33 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000002095 86.0
HKD2_k127_3966540_34 PFAM Fimbrial assembly family protein K02461 - - 0.00002712 57.0
HKD2_k127_3966540_35 Peptidase propeptide and YPEB domain - - - 0.00006775 53.0
HKD2_k127_3966540_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 489.0
HKD2_k127_3966540_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 471.0
HKD2_k127_3966540_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 467.0
HKD2_k127_3966540_7 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 410.0
HKD2_k127_3966540_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 391.0
HKD2_k127_3966540_9 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
HKD2_k127_3967961_0 polysaccharide deacetylase K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 580.0
HKD2_k127_3967961_1 Glycosyl hydrolase family 3 C-terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 573.0
HKD2_k127_3967961_2 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000004167 66.0
HKD2_k127_3990654_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1146.0
HKD2_k127_3990654_1 Hsp70 protein K03569 - - 5.879e-205 640.0
HKD2_k127_3990654_10 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000008518 51.0
HKD2_k127_3990654_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.103e-197 644.0
HKD2_k127_3990654_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 1.582e-195 615.0
HKD2_k127_3990654_4 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 556.0
HKD2_k127_3990654_5 Cell cycle protein K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 524.0
HKD2_k127_3990654_6 rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001618 258.0
HKD2_k127_3990654_7 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000005907 176.0
HKD2_k127_3990654_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000001048 144.0
HKD2_k127_3990654_9 23S rRNA-intervening sequence protein - - - 0.000000000000000000642 91.0
HKD2_k127_3995608_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 0.0 1538.0
HKD2_k127_3995608_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1094.0
HKD2_k127_3995608_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 510.0
HKD2_k127_3995608_11 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 504.0
HKD2_k127_3995608_12 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 505.0
HKD2_k127_3995608_13 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 471.0
HKD2_k127_3995608_14 Glucose inhibited division protein A K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 454.0
HKD2_k127_3995608_15 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 439.0
HKD2_k127_3995608_16 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 425.0
HKD2_k127_3995608_17 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 413.0
HKD2_k127_3995608_18 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 404.0
HKD2_k127_3995608_19 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 369.0
HKD2_k127_3995608_2 Insulinase (Peptidase family M16) K07263 - - 4e-323 1013.0
HKD2_k127_3995608_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 366.0
HKD2_k127_3995608_21 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 333.0
HKD2_k127_3995608_22 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 334.0
HKD2_k127_3995608_23 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 332.0
HKD2_k127_3995608_24 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
HKD2_k127_3995608_25 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
HKD2_k127_3995608_26 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007089 271.0
HKD2_k127_3995608_27 mannonate dehydratase activity K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003159 262.0
HKD2_k127_3995608_28 2-dehydro-3-deoxy-phosphogluconate aldolase activity K00874,K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.1.45,4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000005324 277.0
HKD2_k127_3995608_29 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 269.0
HKD2_k127_3995608_3 ABC transporter transmembrane region - - - 1.021e-242 779.0
HKD2_k127_3995608_30 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001564 265.0
HKD2_k127_3995608_31 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000146 258.0
HKD2_k127_3995608_32 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008816 249.0
HKD2_k127_3995608_33 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004004 258.0
HKD2_k127_3995608_34 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HKD2_k127_3995608_35 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000003101 243.0
HKD2_k127_3995608_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 228.0
HKD2_k127_3995608_37 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000001747 238.0
HKD2_k127_3995608_38 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000962 223.0
HKD2_k127_3995608_39 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000001963 213.0
HKD2_k127_3995608_4 glucuronate isomerase K01812 - 5.3.1.12 4.491e-212 669.0
HKD2_k127_3995608_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001781 205.0
HKD2_k127_3995608_41 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
HKD2_k127_3995608_42 Peptidase, M28 family - - - 0.0000000000000000000000000000000000000000000000000000003282 221.0
HKD2_k127_3995608_43 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000009579 194.0
HKD2_k127_3995608_44 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001648 172.0
HKD2_k127_3995608_45 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000501 160.0
HKD2_k127_3995608_46 - - - - 0.00000000000000000000000000000000000000001118 158.0
HKD2_k127_3995608_48 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000305 139.0
HKD2_k127_3995608_49 Pathogenicity locus - - - 0.00000000000000000000000000000006063 127.0
HKD2_k127_3995608_5 Amino acid permease K03294 - - 2.664e-199 631.0
HKD2_k127_3995608_50 - - - - 0.000000000000000000000000001291 113.0
HKD2_k127_3995608_51 Vitamin K epoxide reductase family - - - 0.0000000000000000000000008829 110.0
HKD2_k127_3995608_52 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000004703 100.0
HKD2_k127_3995608_54 Helix-hairpin-helix motif K02237 - - 0.000000000000000002627 92.0
HKD2_k127_3995608_56 Domain of unknown function (DUF1707) - - - 0.00000000000003056 80.0
HKD2_k127_3995608_57 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000003763 69.0
HKD2_k127_3995608_58 Transcriptional regulator PadR family protein - - - 0.00007714 53.0
HKD2_k127_3995608_59 - - - - 0.0002564 48.0
HKD2_k127_3995608_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 605.0
HKD2_k127_3995608_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 581.0
HKD2_k127_3995608_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 565.0
HKD2_k127_3995608_9 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 550.0
HKD2_k127_4018190_0 Zinc carboxypeptidase - - - 0.0 1408.0
HKD2_k127_4018190_1 Peptidase family M1 domain - - - 3.502e-295 918.0
HKD2_k127_4018190_10 RDD family K06384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 505.0
HKD2_k127_4018190_11 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 503.0
HKD2_k127_4018190_12 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 465.0
HKD2_k127_4018190_13 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 460.0
HKD2_k127_4018190_14 PFAM ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 424.0
HKD2_k127_4018190_15 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 400.0
HKD2_k127_4018190_16 DNA polymerase LigD, ligase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 405.0
HKD2_k127_4018190_17 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 383.0
HKD2_k127_4018190_18 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 342.0
HKD2_k127_4018190_19 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 333.0
HKD2_k127_4018190_2 Spermine/spermidine synthase domain - - - 3.38e-292 919.0
HKD2_k127_4018190_20 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001795 274.0
HKD2_k127_4018190_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001306 278.0
HKD2_k127_4018190_22 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003701 260.0
HKD2_k127_4018190_23 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HKD2_k127_4018190_24 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001255 271.0
HKD2_k127_4018190_25 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001087 268.0
HKD2_k127_4018190_26 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000001662 243.0
HKD2_k127_4018190_27 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
HKD2_k127_4018190_28 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HKD2_k127_4018190_29 Belongs to the TPP enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000008661 219.0
HKD2_k127_4018190_3 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.807e-287 916.0
HKD2_k127_4018190_30 Participates in the control of copper homeostasis K06201 - - 0.0000000000000000000000000000000000000000000000001979 192.0
HKD2_k127_4018190_32 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000001796 166.0
HKD2_k127_4018190_33 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000424 168.0
HKD2_k127_4018190_34 Penicillinase repressor - - - 0.000000000000000000000000000000000000000001736 158.0
HKD2_k127_4018190_35 -acetyltransferase - - - 0.0000000000000000000000000000001003 142.0
HKD2_k127_4018190_36 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000003242 129.0
HKD2_k127_4018190_37 Protein of unknown function (DUF3565) - - - 0.000000000000000000000008591 111.0
HKD2_k127_4018190_38 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000001237 104.0
HKD2_k127_4018190_39 DEAD-like helicases superfamily - - - 0.0000000000000000000001684 109.0
HKD2_k127_4018190_4 cellulose binding - - - 1.166e-276 884.0
HKD2_k127_4018190_40 - - - - 0.00000000000000004441 83.0
HKD2_k127_4018190_42 pathogenesis K02417,K02519 - - 0.000000000009713 77.0
HKD2_k127_4018190_43 Bacterial Ig-like domain 2 - - - 0.000002973 57.0
HKD2_k127_4018190_44 Putative MetA-pathway of phenol degradation - - - 0.000005605 59.0
HKD2_k127_4018190_5 PFAM ABC transporter transmembrane K06147 - - 1.605e-266 835.0
HKD2_k127_4018190_6 MacB-like periplasmic core domain - - - 7.274e-232 746.0
HKD2_k127_4018190_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 587.0
HKD2_k127_4018190_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 583.0
HKD2_k127_4018190_9 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 537.0
HKD2_k127_4018830_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.11e-290 902.0
HKD2_k127_4018830_1 Bacterial membrane protein YfhO - - - 2.634e-261 828.0
HKD2_k127_4018830_10 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 313.0
HKD2_k127_4018830_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 324.0
HKD2_k127_4018830_12 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 291.0
HKD2_k127_4018830_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
HKD2_k127_4018830_14 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000946 212.0
HKD2_k127_4018830_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000004933 185.0
HKD2_k127_4018830_16 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000002968 107.0
HKD2_k127_4018830_17 ribosomal protein - - - 0.000000000000000000399 93.0
HKD2_k127_4018830_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 2.876e-259 806.0
HKD2_k127_4018830_3 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 490.0
HKD2_k127_4018830_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
HKD2_k127_4018830_5 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 427.0
HKD2_k127_4018830_6 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 406.0
HKD2_k127_4018830_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 378.0
HKD2_k127_4018830_8 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 365.0
HKD2_k127_4022117_0 cellulose binding - - - 0.0 1480.0
HKD2_k127_4022117_1 MacB-like periplasmic core domain - - - 2.03e-322 1006.0
HKD2_k127_4022117_10 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 451.0
HKD2_k127_4022117_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 444.0
HKD2_k127_4022117_12 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 402.0
HKD2_k127_4022117_13 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 374.0
HKD2_k127_4022117_14 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 357.0
HKD2_k127_4022117_15 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 342.0
HKD2_k127_4022117_16 competence protein COMEC K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 357.0
HKD2_k127_4022117_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 316.0
HKD2_k127_4022117_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000001026 231.0
HKD2_k127_4022117_19 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000168 216.0
HKD2_k127_4022117_2 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 1.037e-240 761.0
HKD2_k127_4022117_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000001653 203.0
HKD2_k127_4022117_21 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000001857 190.0
HKD2_k127_4022117_22 - - - - 0.00000000000000000000000000000000000000000000000000664 196.0
HKD2_k127_4022117_23 aminopeptidase activity K07004 - - 0.00000000000000000000000001893 111.0
HKD2_k127_4022117_24 Cysteine-rich CPXCG - - - 0.00000000000000000000000002798 117.0
HKD2_k127_4022117_25 - - - - 0.000000000000000008313 88.0
HKD2_k127_4022117_28 energy transducer activity K03832 - - 0.000005201 55.0
HKD2_k127_4022117_29 Protein with unknown function (DUF469) - - - 0.0000355 51.0
HKD2_k127_4022117_3 Peptidase family M28 - - - 2.158e-218 691.0
HKD2_k127_4022117_4 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 591.0
HKD2_k127_4022117_5 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 554.0
HKD2_k127_4022117_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 524.0
HKD2_k127_4022117_7 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 516.0
HKD2_k127_4022117_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 521.0
HKD2_k127_4022117_9 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 469.0
HKD2_k127_4033926_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 595.0
HKD2_k127_4033926_1 PglZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 552.0
HKD2_k127_4033926_10 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 317.0
HKD2_k127_4033926_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
HKD2_k127_4033926_12 Cytochrome c K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002272 289.0
HKD2_k127_4033926_13 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000001204 248.0
HKD2_k127_4033926_14 DnaB-like helicase C terminal domain K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000003194 235.0
HKD2_k127_4033926_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000002628 228.0
HKD2_k127_4033926_16 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000586 212.0
HKD2_k127_4033926_17 UPF0316 protein - - - 0.000000000000000000000000000000000000008798 151.0
HKD2_k127_4033926_18 Preprotein translocase subunit K03210 - - 0.00000000000000000000000001957 116.0
HKD2_k127_4033926_19 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001371 108.0
HKD2_k127_4033926_2 Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 560.0
HKD2_k127_4033926_20 - - - - 0.00000000000000000007033 95.0
HKD2_k127_4033926_22 - - - - 0.000000000002695 71.0
HKD2_k127_4033926_23 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000007605 59.0
HKD2_k127_4033926_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 540.0
HKD2_k127_4033926_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 541.0
HKD2_k127_4033926_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 457.0
HKD2_k127_4033926_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 456.0
HKD2_k127_4033926_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 403.0
HKD2_k127_4033926_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 353.0
HKD2_k127_4033926_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 336.0
HKD2_k127_4057763_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.659e-289 908.0
HKD2_k127_4057763_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 583.0
HKD2_k127_4057763_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 494.0
HKD2_k127_4057763_3 2-dehydropantoate 2-reductase activity K00077,K01295 - 1.1.1.169,3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 447.0
HKD2_k127_4057763_4 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 405.0
HKD2_k127_4057763_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 366.0
HKD2_k127_4057763_6 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 349.0
HKD2_k127_4057763_7 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006842 286.0
HKD2_k127_4057763_8 - - - - 0.000000000000000000000000000000000001356 151.0
HKD2_k127_4082008_0 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 563.0
HKD2_k127_4082008_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 543.0
HKD2_k127_4082008_2 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000001141 253.0
HKD2_k127_4082008_3 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000003825 136.0
HKD2_k127_4082008_4 Isochorismatase family - - - 0.00000000000000000000000000000000004382 142.0
HKD2_k127_419452_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 8.929e-210 655.0
HKD2_k127_419452_1 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.0000000000000000000000000000000000000003339 157.0
HKD2_k127_419452_2 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000000000000001896 134.0
HKD2_k127_419452_3 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000001557 80.0
HKD2_k127_419452_4 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000001142 59.0
HKD2_k127_4218093_0 protein kinase activity K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 559.0
HKD2_k127_4218093_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 534.0
HKD2_k127_4218093_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 500.0
HKD2_k127_4218093_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 497.0
HKD2_k127_4218093_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 421.0
HKD2_k127_4218093_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000267 277.0
HKD2_k127_4218093_6 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006841 276.0
HKD2_k127_4218093_7 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001948 222.0
HKD2_k127_4218093_8 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000008014 151.0
HKD2_k127_4218093_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000005612 85.0
HKD2_k127_425071_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005886 251.0
HKD2_k127_425071_1 Bacterial Ig-like domain 2 - - - 0.000000000000000000006547 108.0
HKD2_k127_425071_2 Helix-turn-helix domain - - - 0.000000000003297 74.0
HKD2_k127_425071_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00009022 55.0
HKD2_k127_4253405_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1328.0
HKD2_k127_4253405_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.003e-290 914.0
HKD2_k127_4253405_10 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 604.0
HKD2_k127_4253405_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 573.0
HKD2_k127_4253405_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 563.0
HKD2_k127_4253405_13 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 564.0
HKD2_k127_4253405_14 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 555.0
HKD2_k127_4253405_15 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 536.0
HKD2_k127_4253405_16 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 538.0
HKD2_k127_4253405_17 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 535.0
HKD2_k127_4253405_18 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 534.0
HKD2_k127_4253405_19 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 496.0
HKD2_k127_4253405_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.807e-288 892.0
HKD2_k127_4253405_20 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 486.0
HKD2_k127_4253405_21 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 481.0
HKD2_k127_4253405_22 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 462.0
HKD2_k127_4253405_23 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
HKD2_k127_4253405_24 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 442.0
HKD2_k127_4253405_25 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 442.0
HKD2_k127_4253405_26 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 454.0
HKD2_k127_4253405_27 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 448.0
HKD2_k127_4253405_28 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 412.0
HKD2_k127_4253405_29 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 402.0
HKD2_k127_4253405_3 Ftsk_gamma K03466 - - 1.353e-273 863.0
HKD2_k127_4253405_30 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 398.0
HKD2_k127_4253405_31 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 379.0
HKD2_k127_4253405_32 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 384.0
HKD2_k127_4253405_33 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 370.0
HKD2_k127_4253405_34 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 356.0
HKD2_k127_4253405_35 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 338.0
HKD2_k127_4253405_36 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 327.0
HKD2_k127_4253405_37 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 318.0
HKD2_k127_4253405_38 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001092 283.0
HKD2_k127_4253405_39 Met-10+ like-protein K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001834 289.0
HKD2_k127_4253405_4 B3/4 domain K01890 - 6.1.1.20 5.166e-263 835.0
HKD2_k127_4253405_40 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004333 266.0
HKD2_k127_4253405_41 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
HKD2_k127_4253405_42 Arginine K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 265.0
HKD2_k127_4253405_43 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000003445 265.0
HKD2_k127_4253405_44 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001428 250.0
HKD2_k127_4253405_45 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
HKD2_k127_4253405_46 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000001113 247.0
HKD2_k127_4253405_47 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
HKD2_k127_4253405_48 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004761 232.0
HKD2_k127_4253405_49 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000006887 224.0
HKD2_k127_4253405_5 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.561e-253 786.0
HKD2_k127_4253405_50 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
HKD2_k127_4253405_51 transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000404 231.0
HKD2_k127_4253405_52 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD2_k127_4253405_53 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000006881 217.0
HKD2_k127_4253405_54 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000006341 207.0
HKD2_k127_4253405_55 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000003829 220.0
HKD2_k127_4253405_56 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000009163 196.0
HKD2_k127_4253405_57 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000001831 187.0
HKD2_k127_4253405_58 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000002938 196.0
HKD2_k127_4253405_59 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000007798 177.0
HKD2_k127_4253405_6 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 1.251e-219 726.0
HKD2_k127_4253405_60 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000000000000000002787 175.0
HKD2_k127_4253405_61 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000956 167.0
HKD2_k127_4253405_62 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000000000003415 163.0
HKD2_k127_4253405_63 HIT domain K02503 - - 0.00000000000000000000000000000000000000004398 161.0
HKD2_k127_4253405_64 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000002412 163.0
HKD2_k127_4253405_65 OmpA family K03640 - - 0.0000000000000000000000000000000000000006692 159.0
HKD2_k127_4253405_66 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000001523 151.0
HKD2_k127_4253405_67 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000009827 148.0
HKD2_k127_4253405_68 Domain of unknown function (DUF4321) - - - 0.0000000000000000000000000000000157 129.0
HKD2_k127_4253405_69 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000000000000000815 132.0
HKD2_k127_4253405_7 Aromatic amino acid lyase K01745 - 4.3.1.3 7.334e-215 679.0
HKD2_k127_4253405_70 Ribosomal protein S21 K02970 - - 0.0000000000000000000000000014 116.0
HKD2_k127_4253405_72 Ribosomal protein L35 K02916 - - 0.0000000000000000009276 95.0
HKD2_k127_4253405_73 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000135 91.0
HKD2_k127_4253405_74 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000005435 86.0
HKD2_k127_4253405_75 - - - - 0.000000002282 66.0
HKD2_k127_4253405_76 cellulase activity K06882 - - 0.00000001805 66.0
HKD2_k127_4253405_8 DHH family K07462 - - 3.491e-199 635.0
HKD2_k127_4253405_9 SurA N-terminal domain K03770 - 5.2.1.8 9.948e-194 622.0
HKD2_k127_4262302_0 Peptidase S46 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 530.0
HKD2_k127_4262302_1 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 426.0
HKD2_k127_4262302_2 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000003165 130.0
HKD2_k127_4262302_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K16216 - 1.1.1.320 0.000000000000000001512 96.0
HKD2_k127_4262302_6 Protein of unknown function (DUF2892) - - - 0.00000000009095 71.0
HKD2_k127_4262302_7 Protein of unknown function (DUF1697) - - - 0.00000193 57.0
HKD2_k127_4265709_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 3.903e-258 801.0
HKD2_k127_4265709_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 461.0
HKD2_k127_4265709_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 404.0
HKD2_k127_4265709_4 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000003856 103.0
HKD2_k127_4333481_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 344.0
HKD2_k127_4333481_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 291.0
HKD2_k127_4333481_2 Domain of unknown function (DUF2382) - - - 0.00000000000000000000000000000000000000000000000000000000000000006218 238.0
HKD2_k127_4333481_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001638 131.0
HKD2_k127_4333481_4 Domain of unknown function (DUF2382) - - - 0.00000000000000005967 87.0
HKD2_k127_4333481_5 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.0000000002157 75.0
HKD2_k127_4381667_0 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 332.0
HKD2_k127_4381667_1 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 317.0
HKD2_k127_4381667_2 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 309.0
HKD2_k127_4381667_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 310.0
HKD2_k127_4381667_4 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00005191 55.0
HKD2_k127_444172_0 Amidohydrolase family - - - 0.0 1648.0
HKD2_k127_444172_1 ERAP1-like C-terminal domain K01256 - 3.4.11.2 1.667e-304 957.0
HKD2_k127_444172_10 BFD domain protein 2Fe-2S -binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 359.0
HKD2_k127_444172_11 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 323.0
HKD2_k127_444172_12 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 275.0
HKD2_k127_444172_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008966 259.0
HKD2_k127_444172_14 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
HKD2_k127_444172_15 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
HKD2_k127_444172_16 COG1125 ABC-type proline glycine betaine transport systems ATPase components K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000002079 236.0
HKD2_k127_444172_17 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001634 225.0
HKD2_k127_444172_18 PFAM regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000003357 211.0
HKD2_k127_444172_19 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus K00125,K00441 - 1.12.98.1,1.17.1.9 0.000000000000000000000000000000000000000000000000000001319 210.0
HKD2_k127_444172_2 phosphoribosylamine-glycine ligase activity K01945 - 6.3.4.13 1.58e-201 635.0
HKD2_k127_444172_20 Nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000001539 183.0
HKD2_k127_444172_21 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000006377 181.0
HKD2_k127_444172_22 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000000000002691 119.0
HKD2_k127_444172_23 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000008907 109.0
HKD2_k127_444172_25 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000489 63.0
HKD2_k127_444172_26 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.0005362 51.0
HKD2_k127_444172_27 Nitronate monooxygenase - - - 0.0006531 44.0
HKD2_k127_444172_3 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 589.0
HKD2_k127_444172_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 536.0
HKD2_k127_444172_5 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 529.0
HKD2_k127_444172_6 stress-induced mitochondrial fusion - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 476.0
HKD2_k127_444172_7 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 396.0
HKD2_k127_444172_8 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 370.0
HKD2_k127_444172_9 transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
HKD2_k127_4449437_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 2.274e-315 985.0
HKD2_k127_4449437_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.689e-287 924.0
HKD2_k127_4449437_10 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 514.0
HKD2_k127_4449437_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 495.0
HKD2_k127_4449437_12 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 495.0
HKD2_k127_4449437_13 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 479.0
HKD2_k127_4449437_14 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 473.0
HKD2_k127_4449437_15 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 465.0
HKD2_k127_4449437_16 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 422.0
HKD2_k127_4449437_17 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 423.0
HKD2_k127_4449437_18 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 406.0
HKD2_k127_4449437_19 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 405.0
HKD2_k127_4449437_2 Surface antigen K07277 - - 7.049e-283 891.0
HKD2_k127_4449437_20 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 399.0
HKD2_k127_4449437_21 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 362.0
HKD2_k127_4449437_22 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 351.0
HKD2_k127_4449437_23 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 327.0
HKD2_k127_4449437_24 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
HKD2_k127_4449437_25 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 304.0
HKD2_k127_4449437_26 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001734 265.0
HKD2_k127_4449437_27 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
HKD2_k127_4449437_28 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000001906 213.0
HKD2_k127_4449437_29 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000006789 207.0
HKD2_k127_4449437_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 2.144e-249 773.0
HKD2_k127_4449437_30 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000002958 207.0
HKD2_k127_4449437_31 UvrB/uvrC motif K19411 - - 0.0000000000000000000000000000000000000000000000000000000232 207.0
HKD2_k127_4449437_32 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000006347 203.0
HKD2_k127_4449437_33 - - - - 0.000000000000000000000000000000000000000000000000000002624 205.0
HKD2_k127_4449437_34 acr, cog1993 K09137 - - 0.0000000000000000000000000000000000000000000002363 173.0
HKD2_k127_4449437_35 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000005195 165.0
HKD2_k127_4449437_36 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000005158 161.0
HKD2_k127_4449437_37 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000005575 145.0
HKD2_k127_4449437_38 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000573 134.0
HKD2_k127_4449437_39 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - 0.00000000000000000000000000000003761 138.0
HKD2_k127_4449437_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.271e-229 730.0
HKD2_k127_4449437_40 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000000004643 124.0
HKD2_k127_4449437_41 - - - - 0.0000000000000000000000000000004678 134.0
HKD2_k127_4449437_42 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000001006 119.0
HKD2_k127_4449437_43 Trm112p-like protein K09791 - - 0.00000000000000000000007265 103.0
HKD2_k127_4449437_44 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000008049 83.0
HKD2_k127_4449437_45 COG NOG15344 non supervised orthologous group - - - 0.0000000000415 64.0
HKD2_k127_4449437_46 COG NOG15344 non supervised orthologous group - - - 0.00003947 48.0
HKD2_k127_4449437_5 Protein of unknown function (DUF512) - - - 1.29e-213 671.0
HKD2_k127_4449437_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.386e-212 668.0
HKD2_k127_4449437_7 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 581.0
HKD2_k127_4449437_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 563.0
HKD2_k127_4449437_9 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 559.0
HKD2_k127_4472683_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 360.0
HKD2_k127_4472683_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000003877 222.0
HKD2_k127_4472683_2 YceI-like domain - - - 0.0001702 54.0
HKD2_k127_4490270_0 PQQ enzyme repeat K00117 - 1.1.5.2 8.117e-261 819.0
HKD2_k127_4490270_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 6.937e-251 804.0
HKD2_k127_4490270_10 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 345.0
HKD2_k127_4490270_11 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 329.0
HKD2_k127_4490270_12 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 329.0
HKD2_k127_4490270_13 Domain of unknown function (DUF4974) K07165 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD2_k127_4490270_14 Disulphide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD2_k127_4490270_15 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000000000005693 196.0
HKD2_k127_4490270_16 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000001317 195.0
HKD2_k127_4490270_17 - - - - 0.0000000000000000000000000000000000000000000000000005734 195.0
HKD2_k127_4490270_18 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000001414 192.0
HKD2_k127_4490270_19 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter - - - 0.00000000000000000000000000000000000000000003718 180.0
HKD2_k127_4490270_2 GMC oxidoreductase K19813 - 1.1.5.9 2.679e-240 755.0
HKD2_k127_4490270_20 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000001134 162.0
HKD2_k127_4490270_21 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000001584 161.0
HKD2_k127_4490270_22 glyoxalase III activity - - - 0.000000000000000000000000000000000000001784 159.0
HKD2_k127_4490270_23 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000001261 144.0
HKD2_k127_4490270_24 - - - - 0.00000000000000000000000000000000001165 143.0
HKD2_k127_4490270_25 - - - - 0.0000000000000000000000000000000002993 143.0
HKD2_k127_4490270_26 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000142 127.0
HKD2_k127_4490270_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000003757 131.0
HKD2_k127_4490270_28 - - - - 0.00000000000000000000000001705 116.0
HKD2_k127_4490270_29 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000001457 100.0
HKD2_k127_4490270_3 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.836e-218 688.0
HKD2_k127_4490270_30 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000002378 96.0
HKD2_k127_4490270_31 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000001417 84.0
HKD2_k127_4490270_33 zinc metalloprotease K11749 - - 0.000321 51.0
HKD2_k127_4490270_4 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 610.0
HKD2_k127_4490270_5 Rieske (2fe-2S) K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 564.0
HKD2_k127_4490270_6 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 520.0
HKD2_k127_4490270_7 amino acid K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 404.0
HKD2_k127_4490270_8 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 366.0
HKD2_k127_4490270_9 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
HKD2_k127_45611_0 MacB-like periplasmic core domain - - - 2.214e-214 691.0
HKD2_k127_45611_1 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 361.0
HKD2_k127_45611_2 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000001398 168.0
HKD2_k127_45611_3 YCII-related domain - - - 0.000000000000000000000000008577 120.0
HKD2_k127_4678063_0 4Fe-4S dicluster domain K00184 - - 0.0 1262.0
HKD2_k127_4678063_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1010.0
HKD2_k127_4678063_10 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 434.0
HKD2_k127_4678063_11 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 410.0
HKD2_k127_4678063_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 402.0
HKD2_k127_4678063_13 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 392.0
HKD2_k127_4678063_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 389.0
HKD2_k127_4678063_15 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 391.0
HKD2_k127_4678063_16 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 359.0
HKD2_k127_4678063_17 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 357.0
HKD2_k127_4678063_18 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 321.0
HKD2_k127_4678063_19 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 317.0
HKD2_k127_4678063_2 Prolyl oligopeptidase family - - - 6.861e-318 1002.0
HKD2_k127_4678063_20 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 317.0
HKD2_k127_4678063_21 SpoU rRNA Methylase family K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
HKD2_k127_4678063_22 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
HKD2_k127_4678063_23 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
HKD2_k127_4678063_24 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
HKD2_k127_4678063_25 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000957 245.0
HKD2_k127_4678063_26 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001978 218.0
HKD2_k127_4678063_27 - - - - 0.0000000000000000000000000000000000000184 161.0
HKD2_k127_4678063_29 - - - - 0.00000000002067 66.0
HKD2_k127_4678063_3 Alpha mannosidase, middle domain K01191 - 3.2.1.24 1.069e-274 871.0
HKD2_k127_4678063_4 Heparinase II/III-like protein - - - 4.705e-267 874.0
HKD2_k127_4678063_5 Polysulphide reductase, NrfD K00185 - - 8.258e-247 768.0
HKD2_k127_4678063_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.068e-206 676.0
HKD2_k127_4678063_7 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 536.0
HKD2_k127_4678063_8 Rhodanese Homology Domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 500.0
HKD2_k127_4678063_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 443.0
HKD2_k127_4729432_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.523e-209 660.0
HKD2_k127_4729432_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 501.0
HKD2_k127_4729432_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000002095 101.0
HKD2_k127_4878748_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001421 257.0
HKD2_k127_4878748_1 Putative Ig domain - - - 0.000000000000000004305 98.0
HKD2_k127_4878748_2 ABC transporter substrate-binding protein K15580 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000035 58.0
HKD2_k127_4988760_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1328.0
HKD2_k127_4988760_1 Involved in the tonB-independent uptake of proteins - - - 0.0 1200.0
HKD2_k127_4988760_10 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 578.0
HKD2_k127_4988760_11 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 536.0
HKD2_k127_4988760_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 515.0
HKD2_k127_4988760_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 499.0
HKD2_k127_4988760_14 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 508.0
HKD2_k127_4988760_15 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 483.0
HKD2_k127_4988760_16 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 482.0
HKD2_k127_4988760_17 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 408.0
HKD2_k127_4988760_18 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 399.0
HKD2_k127_4988760_19 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 389.0
HKD2_k127_4988760_2 HELICc2 K03722 - 3.6.4.12 0.0 1149.0
HKD2_k127_4988760_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 374.0
HKD2_k127_4988760_21 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 358.0
HKD2_k127_4988760_22 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 368.0
HKD2_k127_4988760_23 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 341.0
HKD2_k127_4988760_24 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 337.0
HKD2_k127_4988760_25 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 359.0
HKD2_k127_4988760_26 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 343.0
HKD2_k127_4988760_27 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
HKD2_k127_4988760_28 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 332.0
HKD2_k127_4988760_29 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 322.0
HKD2_k127_4988760_3 nuclear chromosome segregation - - - 1.274e-246 802.0
HKD2_k127_4988760_30 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 307.0
HKD2_k127_4988760_31 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 319.0
HKD2_k127_4988760_32 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 311.0
HKD2_k127_4988760_33 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 286.0
HKD2_k127_4988760_34 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001535 289.0
HKD2_k127_4988760_35 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009883 273.0
HKD2_k127_4988760_36 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003449 261.0
HKD2_k127_4988760_37 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000558 271.0
HKD2_k127_4988760_38 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
HKD2_k127_4988760_39 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003298 253.0
HKD2_k127_4988760_4 (ABC) transporter K06147,K06148 - - 8.413e-214 680.0
HKD2_k127_4988760_40 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008045 251.0
HKD2_k127_4988760_41 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000002401 238.0
HKD2_k127_4988760_42 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000244 229.0
HKD2_k127_4988760_43 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000002062 226.0
HKD2_k127_4988760_44 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000001656 244.0
HKD2_k127_4988760_45 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000002931 233.0
HKD2_k127_4988760_46 - - - - 0.00000000000000000000000000000000000000000000000000000000000003884 228.0
HKD2_k127_4988760_47 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000004113 232.0
HKD2_k127_4988760_48 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000008398 209.0
HKD2_k127_4988760_49 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000008793 199.0
HKD2_k127_4988760_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.273e-213 676.0
HKD2_k127_4988760_50 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000000000000000004051 195.0
HKD2_k127_4988760_51 - - - - 0.0000000000000000000000000000000000000000000000008514 185.0
HKD2_k127_4988760_52 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000004291 169.0
HKD2_k127_4988760_53 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000001854 166.0
HKD2_k127_4988760_54 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000005133 167.0
HKD2_k127_4988760_55 - - - - 0.00000000000000000000000000000000000000002391 172.0
HKD2_k127_4988760_56 Control of competence regulator ComK, YlbF/YmcA - - - 0.00000000000000000000000000000000000005726 147.0
HKD2_k127_4988760_57 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000001852 109.0
HKD2_k127_4988760_58 - - - - 0.0000000000000000000000001217 122.0
HKD2_k127_4988760_59 Binds the 23S rRNA K02909 - - 0.000000000000000000000003604 110.0
HKD2_k127_4988760_6 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.514e-203 642.0
HKD2_k127_4988760_60 DUF218 domain - - - 0.000000000000000000000009013 114.0
HKD2_k127_4988760_62 - - - - 0.000000000000000002652 95.0
HKD2_k127_4988760_63 - - - - 0.000000000000000009459 89.0
HKD2_k127_4988760_66 - - - - 0.0004795 50.0
HKD2_k127_4988760_7 - - - - 1.596e-196 622.0
HKD2_k127_4988760_8 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 9.825e-194 608.0
HKD2_k127_4988760_9 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 597.0
HKD2_k127_5112042_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009 373.0
HKD2_k127_5112042_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 294.0
HKD2_k127_5134538_0 transmembrane transporter activity K03296 - - 0.0 1442.0
HKD2_k127_5134538_1 MMPL family K03296 - - 0.0 1124.0
HKD2_k127_5134538_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 282.0
HKD2_k127_5134538_11 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000805 240.0
HKD2_k127_5134538_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003887 242.0
HKD2_k127_5134538_13 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000000003199 228.0
HKD2_k127_5134538_14 SNARE associated Golgi protein K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000002784 199.0
HKD2_k127_5134538_15 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000398 162.0
HKD2_k127_5134538_16 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000005523 145.0
HKD2_k127_5134538_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000001979 133.0
HKD2_k127_5134538_18 - - - - 0.00000000000000000003702 98.0
HKD2_k127_5134538_19 S23 ribosomal protein - - - 0.000000000000001401 82.0
HKD2_k127_5134538_2 FtsX-like permease family K02004 - - 1.229e-254 822.0
HKD2_k127_5134538_20 - - - - 0.00000000001378 67.0
HKD2_k127_5134538_21 - - - - 0.0000000007464 67.0
HKD2_k127_5134538_22 Glucose / Sorbosone dehydrogenase - - - 0.000001531 56.0
HKD2_k127_5134538_3 IMP dehydrogenase activity K03281 - - 2.887e-237 751.0
HKD2_k127_5134538_4 Chlorophyllase enzyme - - - 2.357e-215 694.0
HKD2_k127_5134538_5 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 378.0
HKD2_k127_5134538_6 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid K00101,K16422 - 1.1.2.3,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 364.0
HKD2_k127_5134538_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 344.0
HKD2_k127_5134538_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 308.0
HKD2_k127_5134538_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
HKD2_k127_5135719_0 TonB dependent receptor - - - 0.0 1248.0
HKD2_k127_5135719_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
HKD2_k127_5135719_10 - - - - 0.000004306 55.0
HKD2_k127_5135719_11 - - - - 0.00006572 54.0
HKD2_k127_5135719_2 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 411.0
HKD2_k127_5135719_3 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000007896 200.0
HKD2_k127_5135719_4 SusD family K21572 - - 0.0000000000000000000000000000000000000000000000000008466 205.0
HKD2_k127_5135719_5 PFAM YCII-related domain - - - 0.000000000000000000000000000000000000000000000007812 175.0
HKD2_k127_5135719_6 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000003053 151.0
HKD2_k127_5135719_7 - - - - 0.000000000000000000001676 102.0
HKD2_k127_5135719_8 - - - - 0.000000000000009775 87.0
HKD2_k127_5167569_0 ABC transporter transmembrane region K18889 - - 6.131e-239 754.0
HKD2_k127_5167569_1 Neutral/alkaline non-lysosomal ceramidase, C-terminal K12349 - 3.5.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 515.0
HKD2_k127_5167569_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 377.0
HKD2_k127_5167569_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 345.0
HKD2_k127_5167569_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000367 257.0
HKD2_k127_5167569_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000001927 236.0
HKD2_k127_5167569_6 phosphorelay signal transduction system - - - 0.0000000000000000000006079 100.0
HKD2_k127_5167569_7 - - - - 0.000000000001758 78.0
HKD2_k127_5196302_0 Gamma-glutamyltranspeptidase - - - 0.0 1121.0
HKD2_k127_5196302_1 MacB-like periplasmic core domain - - - 1.549e-240 773.0
HKD2_k127_5196302_10 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 544.0
HKD2_k127_5196302_11 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 505.0
HKD2_k127_5196302_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 517.0
HKD2_k127_5196302_13 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 447.0
HKD2_k127_5196302_14 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 433.0
HKD2_k127_5196302_15 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 422.0
HKD2_k127_5196302_16 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 409.0
HKD2_k127_5196302_17 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
HKD2_k127_5196302_18 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 379.0
HKD2_k127_5196302_19 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 354.0
HKD2_k127_5196302_2 PFAM Circadian clock protein KaiC central region K08482 - - 4.786e-227 721.0
HKD2_k127_5196302_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 317.0
HKD2_k127_5196302_21 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 306.0
HKD2_k127_5196302_22 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 302.0
HKD2_k127_5196302_23 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
HKD2_k127_5196302_24 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
HKD2_k127_5196302_25 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000007677 258.0
HKD2_k127_5196302_26 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000001257 190.0
HKD2_k127_5196302_27 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000000000000000002785 176.0
HKD2_k127_5196302_29 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000002487 163.0
HKD2_k127_5196302_3 Amidohydrolase family K06015 - 3.5.1.81 7.441e-216 691.0
HKD2_k127_5196302_30 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000002842 159.0
HKD2_k127_5196302_31 COG3668 Plasmid stabilization system protein - - - 0.0000000000000000000000000000000000000002176 161.0
HKD2_k127_5196302_32 - - - - 0.0000000000000000000000000000004856 138.0
HKD2_k127_5196302_33 KaiB K08481 - - 0.00000000000000000000000000001108 123.0
HKD2_k127_5196302_34 - - - - 0.0000000000000000832 83.0
HKD2_k127_5196302_35 - - - - 0.00000000000004811 79.0
HKD2_k127_5196302_37 Helix-turn-helix domain - - - 0.000000000008799 69.0
HKD2_k127_5196302_38 - - - - 0.00000002131 62.0
HKD2_k127_5196302_4 efflux transmembrane transporter activity K02004 - - 8.921e-194 636.0
HKD2_k127_5196302_41 Protein kinase domain K12132 - 2.7.11.1 0.0005076 46.0
HKD2_k127_5196302_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 611.0
HKD2_k127_5196302_6 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 596.0
HKD2_k127_5196302_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 604.0
HKD2_k127_5196302_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 582.0
HKD2_k127_5196302_9 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 587.0
HKD2_k127_5199984_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1543.0
HKD2_k127_5199984_1 Sortilin, neurotensin receptor 3, - - - 0.0 1513.0
HKD2_k127_5199984_10 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 408.0
HKD2_k127_5199984_11 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 391.0
HKD2_k127_5199984_12 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 387.0
HKD2_k127_5199984_13 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 349.0
HKD2_k127_5199984_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 350.0
HKD2_k127_5199984_15 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
HKD2_k127_5199984_16 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
HKD2_k127_5199984_17 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 314.0
HKD2_k127_5199984_18 Domain of unknown function (DUF1906) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 308.0
HKD2_k127_5199984_19 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000003044 220.0
HKD2_k127_5199984_2 AcrB/AcrD/AcrF family K03296 - - 0.0 1416.0
HKD2_k127_5199984_20 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
HKD2_k127_5199984_21 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000000000000000000000000000001078 190.0
HKD2_k127_5199984_22 MOSC domain - - - 0.000000000000000000000000000000000000000000000007331 184.0
HKD2_k127_5199984_23 unfolded protein binding K18481 - - 0.00000000000000000000000000000000000000000000002497 180.0
HKD2_k127_5199984_24 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.00000000000000000000000000000000000000000000009126 185.0
HKD2_k127_5199984_25 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000001201 174.0
HKD2_k127_5199984_26 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000004217 166.0
HKD2_k127_5199984_27 - - - - 0.0000000000000000000000000000000000000000002138 169.0
HKD2_k127_5199984_28 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000007425 164.0
HKD2_k127_5199984_29 Transcriptional regulator - - - 0.00000000000000000000000000000001515 131.0
HKD2_k127_5199984_3 ABC transporter K06020 - 3.6.3.25 1.948e-257 805.0
HKD2_k127_5199984_30 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000007974 129.0
HKD2_k127_5199984_31 Erythromycin esterase K06880 - - 0.00000000000000000000006914 113.0
HKD2_k127_5199984_33 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000001659 93.0
HKD2_k127_5199984_35 - - - - 0.0000000000005679 79.0
HKD2_k127_5199984_36 Domain of unknown function (DUF4142) K08995 - - 0.0001502 52.0
HKD2_k127_5199984_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 577.0
HKD2_k127_5199984_5 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 556.0
HKD2_k127_5199984_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 520.0
HKD2_k127_5199984_7 phosphorelay signal transduction system K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 464.0
HKD2_k127_5199984_8 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 451.0
HKD2_k127_5199984_9 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 442.0
HKD2_k127_521800_0 Dehydrogenase - - - 3.073e-318 984.0
HKD2_k127_521800_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 474.0
HKD2_k127_521800_10 DinB family - - - 0.0000000000000000009854 96.0
HKD2_k127_521800_2 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 354.0
HKD2_k127_521800_3 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007915 299.0
HKD2_k127_521800_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002857 256.0
HKD2_k127_521800_5 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000217 209.0
HKD2_k127_521800_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000009297 206.0
HKD2_k127_521800_7 Yip1 domain - - - 0.000000000000000000000000000005402 129.0
HKD2_k127_521800_8 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.0000000000000000000004056 100.0
HKD2_k127_525653_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.491e-298 930.0
HKD2_k127_525653_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 6.725e-294 940.0
HKD2_k127_525653_10 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 416.0
HKD2_k127_525653_11 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 397.0
HKD2_k127_525653_12 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 386.0
HKD2_k127_525653_13 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 387.0
HKD2_k127_525653_14 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006572 279.0
HKD2_k127_525653_15 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002511 254.0
HKD2_k127_525653_16 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000002117 233.0
HKD2_k127_525653_17 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000001319 222.0
HKD2_k127_525653_18 EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000002996 226.0
HKD2_k127_525653_19 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000004266 204.0
HKD2_k127_525653_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.362e-288 891.0
HKD2_k127_525653_20 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000001392 204.0
HKD2_k127_525653_21 Thioredoxin - - - 0.000000000000000000000000000000000000000009103 162.0
HKD2_k127_525653_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000009823 121.0
HKD2_k127_525653_23 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000002871 102.0
HKD2_k127_525653_25 MotA/TolQ/ExbB proton channel family - - - 0.00000002559 66.0
HKD2_k127_525653_27 - - - - 0.00001271 48.0
HKD2_k127_525653_28 23S rRNA-intervening sequence protein - - - 0.00005615 53.0
HKD2_k127_525653_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.405e-270 837.0
HKD2_k127_525653_30 - - - - 0.0001665 45.0
HKD2_k127_525653_4 tRNA synthetases class I (M) K01874 - 6.1.1.10 9.127e-249 779.0
HKD2_k127_525653_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 553.0
HKD2_k127_525653_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 515.0
HKD2_k127_525653_7 EAL domain K13950,K21025 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 487.0
HKD2_k127_525653_8 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 458.0
HKD2_k127_525653_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
HKD2_k127_5264706_0 amino acid activation for nonribosomal peptide biosynthetic process K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 431.0
HKD2_k127_5264706_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
HKD2_k127_5264706_2 - - - - 0.000000000000000000000000000000005084 134.0
HKD2_k127_5264706_3 ABC-2 family transporter protein - - - 0.000000000000000000000000006912 124.0
HKD2_k127_5291291_0 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 547.0
HKD2_k127_5291291_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 465.0
HKD2_k127_5291291_2 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 290.0
HKD2_k127_5291291_3 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD2_k127_5291291_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000004322 202.0
HKD2_k127_5291291_5 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000001061 194.0
HKD2_k127_5291291_6 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000005446 171.0
HKD2_k127_5291291_7 - - - - 0.000000000001014 79.0
HKD2_k127_5316509_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 555.0
HKD2_k127_5316509_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 315.0
HKD2_k127_5316509_2 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 322.0
HKD2_k127_5316509_3 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000002621 214.0
HKD2_k127_5316509_4 - - - - 0.00000000000000000000000000000000000000000000000000000008724 203.0
HKD2_k127_5316509_5 - - - - 0.000000000000000000000000000000000000000000008065 172.0
HKD2_k127_5351935_0 domain, Protein K01212,K12287,K20276 - 3.2.1.65 9.792e-319 1032.0
HKD2_k127_5351935_1 domain, Protein K01212,K12287,K20276 - 3.2.1.65 2.871e-261 855.0
HKD2_k127_5351935_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 379.0
HKD2_k127_5351935_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 376.0
HKD2_k127_5351935_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 363.0
HKD2_k127_5351935_13 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000009852 233.0
HKD2_k127_5351935_14 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000004729 227.0
HKD2_k127_5351935_15 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000003263 225.0
HKD2_k127_5351935_16 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000001834 207.0
HKD2_k127_5351935_17 Methyltransferase domain - - - 0.0000000000000000000278 102.0
HKD2_k127_5351935_19 SMART Tetratricopeptide domain protein - - - 0.00000752 52.0
HKD2_k127_5351935_2 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 523.0
HKD2_k127_5351935_20 regulator - - - 0.0001122 52.0
HKD2_k127_5351935_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 519.0
HKD2_k127_5351935_4 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 506.0
HKD2_k127_5351935_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 505.0
HKD2_k127_5351935_6 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 497.0
HKD2_k127_5351935_7 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 491.0
HKD2_k127_5351935_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 438.0
HKD2_k127_5351935_9 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 375.0
HKD2_k127_5477785_0 Protein export membrane protein - - - 0.0 1589.0
HKD2_k127_5477785_1 esterase - - - 2.732e-263 817.0
HKD2_k127_5477785_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001535 167.0
HKD2_k127_5477785_11 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000000000004937 135.0
HKD2_k127_5477785_12 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000001557 124.0
HKD2_k127_5477785_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000034 116.0
HKD2_k127_5477785_14 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000000003794 118.0
HKD2_k127_5477785_15 transcriptional regulator - - - 0.0000000000000000000000000265 116.0
HKD2_k127_5477785_16 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001102 104.0
HKD2_k127_5477785_17 NADH dehydrogenase - - - 0.000000000000000001981 96.0
HKD2_k127_5477785_18 Ribosomal protein S21 K02970 - - 0.00000000000002088 75.0
HKD2_k127_5477785_2 Protein kinase domain K12132 - 2.7.11.1 3.388e-248 804.0
HKD2_k127_5477785_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 481.0
HKD2_k127_5477785_4 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 484.0
HKD2_k127_5477785_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 363.0
HKD2_k127_5477785_6 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 319.0
HKD2_k127_5477785_7 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 302.0
HKD2_k127_5477785_8 - - - - 0.0000000000000000000000000000000000000000000000000003545 196.0
HKD2_k127_5477785_9 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000125 186.0
HKD2_k127_5508536_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 395.0
HKD2_k127_5508536_1 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 329.0
HKD2_k127_5508536_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001802 268.0
HKD2_k127_5508536_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001009 273.0
HKD2_k127_5508536_4 - - - - 0.0000000000000000000000000002356 116.0
HKD2_k127_5523295_0 TonB-dependent receptor - - - 4.826e-231 751.0
HKD2_k127_5523295_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 307.0
HKD2_k127_5523295_2 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003777 290.0
HKD2_k127_5523295_3 sequence-specific DNA binding K01239,K02855,K07506,K18199 - 3.2.2.1,4.2.1.103 0.00000000000000000000000000000000000003004 148.0
HKD2_k127_5532542_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 604.0
HKD2_k127_5532542_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 510.0
HKD2_k127_5532542_2 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 311.0
HKD2_k127_5532542_3 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 284.0
HKD2_k127_5532542_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000003013 76.0
HKD2_k127_5532542_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000002984 76.0
HKD2_k127_5532542_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000213 72.0
HKD2_k127_5532542_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0002902 51.0
HKD2_k127_5561012_0 Dehydrogenase K00117 - 1.1.5.2 1.147e-313 973.0
HKD2_k127_5561012_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001023 111.0
HKD2_k127_5572555_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 337.0
HKD2_k127_5572555_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001868 288.0
HKD2_k127_5572555_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000006951 257.0
HKD2_k127_5572555_3 C-terminal region of band_7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003839 246.0
HKD2_k127_5572555_4 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000004384 169.0
HKD2_k127_5572555_5 PIN domain K07063 - - 0.0000000000000000001818 95.0
HKD2_k127_5572555_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000001046 77.0
HKD2_k127_565018_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 7.082e-243 762.0
HKD2_k127_565018_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.564e-232 745.0
HKD2_k127_565018_10 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000002741 251.0
HKD2_k127_565018_11 ABC 3 transport family K09819,K11606,K11708,K11709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HKD2_k127_565018_12 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
HKD2_k127_565018_13 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000004077 228.0
HKD2_k127_565018_14 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000006238 179.0
HKD2_k127_565018_15 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000001383 173.0
HKD2_k127_565018_16 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000004129 137.0
HKD2_k127_565018_17 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000022 113.0
HKD2_k127_565018_18 Hydrogenase expression formation protein K04653 - - 0.000000000000000000000464 108.0
HKD2_k127_565018_19 heat shock protein binding - - - 0.00000000000000000299 96.0
HKD2_k127_565018_2 Acylphosphatase K04656 - - 2.849e-194 641.0
HKD2_k127_565018_20 Thiamine-binding protein - - - 0.00000000000022 79.0
HKD2_k127_565018_21 Domain of unknown function (DUF4342) - - - 0.0000000000003054 78.0
HKD2_k127_565018_22 BON domain - - - 0.000000002555 67.0
HKD2_k127_565018_23 Domain of unknown function (DUF4136) - - - 0.0000001112 61.0
HKD2_k127_565018_24 Archease protein family (MTH1598/TM1083) - - - 0.0000007311 57.0
HKD2_k127_565018_25 Universal stress protein family - - - 0.000006343 58.0
HKD2_k127_565018_26 nickel cation binding K04651 - - 0.00006764 51.0
HKD2_k127_565018_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 544.0
HKD2_k127_565018_4 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 527.0
HKD2_k127_565018_5 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 502.0
HKD2_k127_565018_6 small subunit K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 445.0
HKD2_k127_565018_7 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 383.0
HKD2_k127_565018_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 350.0
HKD2_k127_565018_9 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
HKD2_k127_5663472_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 435.0
HKD2_k127_5663472_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 423.0
HKD2_k127_5663472_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003122 281.0
HKD2_k127_5663472_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000002073 227.0
HKD2_k127_5675703_0 PQQ-like domain K00117 - 1.1.5.2 0.0 1118.0
HKD2_k127_5675703_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 396.0
HKD2_k127_5675703_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000002627 222.0
HKD2_k127_5675703_3 Cytochrome c - - - 0.0000000000000000000000000000000000009205 153.0
HKD2_k127_5711664_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1454.0
HKD2_k127_5711664_1 CarboxypepD_reg-like domain K02014 - - 0.0 1166.0
HKD2_k127_5711664_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 340.0
HKD2_k127_5711664_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 328.0
HKD2_k127_5711664_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 300.0
HKD2_k127_5711664_13 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 306.0
HKD2_k127_5711664_14 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004431 276.0
HKD2_k127_5711664_15 CheC-like family K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001112 272.0
HKD2_k127_5711664_16 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000076 259.0
HKD2_k127_5711664_17 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
HKD2_k127_5711664_18 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000004526 214.0
HKD2_k127_5711664_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000001702 191.0
HKD2_k127_5711664_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1010.0
HKD2_k127_5711664_20 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000000000000004265 192.0
HKD2_k127_5711664_21 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000004995 175.0
HKD2_k127_5711664_22 PFAM CheW domain protein K03408 - - 0.0000000000000002093 86.0
HKD2_k127_5711664_3 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 1.438e-218 712.0
HKD2_k127_5711664_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 493.0
HKD2_k127_5711664_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 488.0
HKD2_k127_5711664_6 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 461.0
HKD2_k127_5711664_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 429.0
HKD2_k127_5711664_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 403.0
HKD2_k127_5711664_9 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 396.0
HKD2_k127_5722108_0 GDSL-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 396.0
HKD2_k127_5722108_1 beta-galactosidase activity K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000809 212.0
HKD2_k127_5722108_2 ABC transporter K10441 - 3.6.3.17 0.000000000000002461 76.0
HKD2_k127_5817699_0 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001367 274.0
HKD2_k127_5817699_1 self proteolysis - - - 0.000000000000009073 90.0
HKD2_k127_5817699_2 -acetyltransferase - - - 0.000000000009346 68.0
HKD2_k127_5864197_0 Amidohydrolase family - - - 1.605e-236 747.0
HKD2_k127_5864197_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 629.0
HKD2_k127_5864197_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 490.0
HKD2_k127_5864197_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 428.0
HKD2_k127_5864197_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 334.0
HKD2_k127_5864197_5 - - - - 0.0000000000000000000000000000000000000000000000001347 190.0
HKD2_k127_5867324_0 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 636.0
HKD2_k127_5867324_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 448.0
HKD2_k127_5867324_2 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 320.0
HKD2_k127_5867324_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003073 286.0
HKD2_k127_5938081_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.12e-211 665.0
HKD2_k127_5938081_1 4Fe-4S binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 543.0
HKD2_k127_5938081_10 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000008043 169.0
HKD2_k127_5938081_2 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 517.0
HKD2_k127_5938081_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 482.0
HKD2_k127_5938081_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 382.0
HKD2_k127_5938081_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
HKD2_k127_5938081_6 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 329.0
HKD2_k127_5938081_7 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 316.0
HKD2_k127_5938081_8 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000012 275.0
HKD2_k127_5938081_9 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003255 243.0
HKD2_k127_596700_0 Collagenase K08303 - - 0.0 1133.0
HKD2_k127_596700_1 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 2.063e-300 930.0
HKD2_k127_596700_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 536.0
HKD2_k127_596700_11 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 516.0
HKD2_k127_596700_12 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 503.0
HKD2_k127_596700_13 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 478.0
HKD2_k127_596700_14 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 450.0
HKD2_k127_596700_15 ribonuclease E activity K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 414.0
HKD2_k127_596700_16 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 390.0
HKD2_k127_596700_17 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 392.0
HKD2_k127_596700_18 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 392.0
HKD2_k127_596700_19 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 398.0
HKD2_k127_596700_2 RecQ zinc-binding K03654 - 3.6.4.12 6.157e-283 884.0
HKD2_k127_596700_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 353.0
HKD2_k127_596700_21 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 333.0
HKD2_k127_596700_22 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 337.0
HKD2_k127_596700_23 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 314.0
HKD2_k127_596700_24 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 306.0
HKD2_k127_596700_25 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008159 276.0
HKD2_k127_596700_26 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006403 286.0
HKD2_k127_596700_27 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006031 247.0
HKD2_k127_596700_28 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001296 229.0
HKD2_k127_596700_29 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000205 208.0
HKD2_k127_596700_3 Carboxyl transferase domain - - - 9.559e-276 875.0
HKD2_k127_596700_30 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000001045 210.0
HKD2_k127_596700_31 - - - - 0.0000000000000000000000000000000000000000000000000000003484 195.0
HKD2_k127_596700_32 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.0000000000000000000000000000000000000000000000000005948 196.0
HKD2_k127_596700_33 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000006146 183.0
HKD2_k127_596700_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000007604 170.0
HKD2_k127_596700_35 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000004328 183.0
HKD2_k127_596700_36 Ribosomal L27 protein K02899 - - 0.00000000000000000000000000000000000000003395 153.0
HKD2_k127_596700_37 - - - - 0.000000000000000000000000000000000001347 153.0
HKD2_k127_596700_38 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000001026 139.0
HKD2_k127_596700_39 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.000000000000000000000000005427 118.0
HKD2_k127_596700_4 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 2.834e-263 822.0
HKD2_k127_596700_40 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000051 108.0
HKD2_k127_596700_41 - - - - 0.000000000000000006309 88.0
HKD2_k127_596700_42 - - - - 0.00000000000000007447 89.0
HKD2_k127_596700_43 PAP2 superfamily - - - 0.0000000001883 72.0
HKD2_k127_596700_44 - - - - 0.0005356 50.0
HKD2_k127_596700_5 Acyclic terpene utilisation family protein AtuA - - - 1.097e-243 765.0
HKD2_k127_596700_6 7TM receptor with intracellular HD hydrolase K07037 - - 9.415e-237 752.0
HKD2_k127_596700_7 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 3.32e-206 650.0
HKD2_k127_596700_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.279e-201 634.0
HKD2_k127_596700_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 535.0
HKD2_k127_6116971_0 peptidase - - - 5.535e-288 904.0
HKD2_k127_6116971_1 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 542.0
HKD2_k127_6116971_2 Starch-binding associating with outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005367 261.0
HKD2_k127_63230_0 amine dehydrogenase activity K17285 - - 1.13e-260 809.0
HKD2_k127_63230_1 Protein kinase domain K12132 - 2.7.11.1 3.605e-225 730.0
HKD2_k127_63230_10 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 394.0
HKD2_k127_63230_11 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 376.0
HKD2_k127_63230_12 Pyridine nucleotide-disulphide oxidoreductase K03885 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 352.0
HKD2_k127_63230_13 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 273.0
HKD2_k127_63230_14 tRNA m6t6A37 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000182 234.0
HKD2_k127_63230_15 HAD-hyrolase-like K19270 - 3.1.3.23 0.000000000000000000000000000000000000000000000000000000000001241 220.0
HKD2_k127_63230_16 - - - - 0.00000000000000000000000000000000000000000000000000000001265 208.0
HKD2_k127_63230_17 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000435 208.0
HKD2_k127_63230_18 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000002485 191.0
HKD2_k127_63230_19 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000003413 192.0
HKD2_k127_63230_2 Tetratricopeptide repeat K12132 - 2.7.11.1 6.451e-222 728.0
HKD2_k127_63230_20 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000894 174.0
HKD2_k127_63230_21 - - - - 0.000000000000000000000000000000000005676 145.0
HKD2_k127_63230_22 DinB family - - - 0.00000000000000000000000000001039 124.0
HKD2_k127_63230_24 Protein of unknown function (DUF3455) - - - 0.00000000000000000000006292 107.0
HKD2_k127_63230_25 RDD family - - - 0.000000000000000007379 89.0
HKD2_k127_63230_26 RNA polymerase sigma factor K03088 - - 0.000000000000002318 83.0
HKD2_k127_63230_28 SnoaL-like domain - - - 0.00000000004504 71.0
HKD2_k127_63230_3 Sugar (and other) transporter - - - 2.904e-206 653.0
HKD2_k127_63230_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 597.0
HKD2_k127_63230_5 PFAM AMP-dependent synthetase and ligase K12429,K18660,K18661,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 600.0
HKD2_k127_63230_6 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 559.0
HKD2_k127_63230_7 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 549.0
HKD2_k127_63230_8 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 540.0
HKD2_k127_63230_9 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 467.0
HKD2_k127_6352725_0 Highly conserved protein containing a thioredoxin domain K06888 - - 1.906e-243 769.0
HKD2_k127_6352725_1 Peptidase dimerisation domain - - - 4.108e-213 675.0
HKD2_k127_6352725_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 391.0
HKD2_k127_6352725_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002331 258.0
HKD2_k127_6352725_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000004857 146.0
HKD2_k127_6388403_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.164e-235 734.0
HKD2_k127_6388403_1 Dehydrogenase K00117 - 1.1.5.2 2.675e-229 731.0
HKD2_k127_6388403_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
HKD2_k127_6388403_11 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002791 265.0
HKD2_k127_6388403_12 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000001339 239.0
HKD2_k127_6388403_13 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000001178 223.0
HKD2_k127_6388403_14 - - - - 0.00000000000000000000000000000000000000000000000000000000003925 221.0
HKD2_k127_6388403_15 - - - - 0.00000000000000000000000000000000000000000000000000003345 203.0
HKD2_k127_6388403_16 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000008169 170.0
HKD2_k127_6388403_17 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000003875 148.0
HKD2_k127_6388403_19 - - - - 0.00000000000000000002663 98.0
HKD2_k127_6388403_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.596e-221 692.0
HKD2_k127_6388403_20 - - - - 0.0000000000000000005554 94.0
HKD2_k127_6388403_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000001596 78.0
HKD2_k127_6388403_22 - - - - 0.00003577 55.0
HKD2_k127_6388403_3 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 576.0
HKD2_k127_6388403_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
HKD2_k127_6388403_5 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 459.0
HKD2_k127_6388403_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 440.0
HKD2_k127_6388403_7 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 456.0
HKD2_k127_6388403_8 Belongs to the bacterial solute-binding protein 9 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 433.0
HKD2_k127_6388403_9 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 351.0
HKD2_k127_6390061_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 2025.0
HKD2_k127_6390061_1 cellulose binding - - - 0.0 1436.0
HKD2_k127_6390061_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 565.0
HKD2_k127_6390061_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 528.0
HKD2_k127_6390061_12 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 530.0
HKD2_k127_6390061_13 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 465.0
HKD2_k127_6390061_14 Protein of unknown function (DUF445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 442.0
HKD2_k127_6390061_15 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 440.0
HKD2_k127_6390061_16 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 437.0
HKD2_k127_6390061_17 response to heat K03695,K03696,K03697,K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 421.0
HKD2_k127_6390061_18 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 430.0
HKD2_k127_6390061_19 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 404.0
HKD2_k127_6390061_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1296.0
HKD2_k127_6390061_20 - K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 398.0
HKD2_k127_6390061_21 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 377.0
HKD2_k127_6390061_22 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 379.0
HKD2_k127_6390061_23 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 341.0
HKD2_k127_6390061_24 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 337.0
HKD2_k127_6390061_25 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 331.0
HKD2_k127_6390061_26 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 324.0
HKD2_k127_6390061_27 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 302.0
HKD2_k127_6390061_28 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 295.0
HKD2_k127_6390061_29 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
HKD2_k127_6390061_3 TonB dependent receptor - - - 0.0 1058.0
HKD2_k127_6390061_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006036 276.0
HKD2_k127_6390061_32 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002798 263.0
HKD2_k127_6390061_33 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000006369 228.0
HKD2_k127_6390061_34 heme binding - - - 0.00000000000000000000000000000000000000000000000000000000000000608 228.0
HKD2_k127_6390061_35 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000007301 223.0
HKD2_k127_6390061_36 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000008346 207.0
HKD2_k127_6390061_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000001382 200.0
HKD2_k127_6390061_38 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000009255 186.0
HKD2_k127_6390061_39 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000002108 179.0
HKD2_k127_6390061_4 TonB-dependent receptor - - - 5e-324 1023.0
HKD2_k127_6390061_40 CYTH - - - 0.00000000000000000000000000000000000000000005355 168.0
HKD2_k127_6390061_41 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000005307 156.0
HKD2_k127_6390061_42 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000000000000003498 150.0
HKD2_k127_6390061_43 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000007746 132.0
HKD2_k127_6390061_44 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000004615 120.0
HKD2_k127_6390061_46 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000005659 60.0
HKD2_k127_6390061_47 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.00002032 55.0
HKD2_k127_6390061_48 Carboxypeptidase regulatory-like domain - - - 0.0006684 51.0
HKD2_k127_6390061_5 TonB dependent receptor - - - 2.586e-304 968.0
HKD2_k127_6390061_6 TonB dependent receptor - - - 3.417e-293 935.0
HKD2_k127_6390061_7 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 4.227e-280 887.0
HKD2_k127_6390061_8 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.143e-228 724.0
HKD2_k127_6390061_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.006e-205 685.0
HKD2_k127_6397791_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 407.0
HKD2_k127_6397791_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 322.0
HKD2_k127_6397791_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
HKD2_k127_6397791_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
HKD2_k127_6397791_4 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000001939 184.0
HKD2_k127_6397791_5 Parallel beta-helix repeats - - - 0.00008475 53.0
HKD2_k127_6412449_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 447.0
HKD2_k127_6412449_1 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
HKD2_k127_6412449_2 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000004816 194.0
HKD2_k127_6412449_3 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000001241 132.0
HKD2_k127_6413568_0 WD40-like Beta Propeller Repeat - - - 1.019e-233 754.0
HKD2_k127_6413568_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 440.0
HKD2_k127_6413568_2 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 346.0
HKD2_k127_6413568_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000006856 196.0
HKD2_k127_6437934_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1394.0
HKD2_k127_6437934_1 Aldehyde dehydrogenase family K00138 - - 3.942e-235 729.0
HKD2_k127_6437934_10 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 480.0
HKD2_k127_6437934_11 cystathionine K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 498.0
HKD2_k127_6437934_12 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 482.0
HKD2_k127_6437934_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 455.0
HKD2_k127_6437934_14 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 455.0
HKD2_k127_6437934_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 459.0
HKD2_k127_6437934_16 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 454.0
HKD2_k127_6437934_17 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 435.0
HKD2_k127_6437934_18 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 431.0
HKD2_k127_6437934_19 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 421.0
HKD2_k127_6437934_2 Amidohydrolase family - - - 5.165e-222 700.0
HKD2_k127_6437934_20 4Fe-4S single cluster domain K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 411.0
HKD2_k127_6437934_21 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 423.0
HKD2_k127_6437934_22 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 422.0
HKD2_k127_6437934_23 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 411.0
HKD2_k127_6437934_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 387.0
HKD2_k127_6437934_25 PFAM ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 372.0
HKD2_k127_6437934_26 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 398.0
HKD2_k127_6437934_27 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HKD2_k127_6437934_28 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 351.0
HKD2_k127_6437934_29 ACT domain K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 374.0
HKD2_k127_6437934_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 630.0
HKD2_k127_6437934_30 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 363.0
HKD2_k127_6437934_31 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 324.0
HKD2_k127_6437934_32 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 342.0
HKD2_k127_6437934_33 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 327.0
HKD2_k127_6437934_34 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 306.0
HKD2_k127_6437934_35 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
HKD2_k127_6437934_36 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001652 285.0
HKD2_k127_6437934_37 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005535 254.0
HKD2_k127_6437934_38 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
HKD2_k127_6437934_39 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000002305 209.0
HKD2_k127_6437934_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 599.0
HKD2_k127_6437934_40 NlpC/P60 family - - - 0.000000000000000000000000000000000000000003716 162.0
HKD2_k127_6437934_41 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000002097 166.0
HKD2_k127_6437934_42 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000005197 166.0
HKD2_k127_6437934_43 OmpA family K03640 - - 0.000000000000000000000000000000000000002115 162.0
HKD2_k127_6437934_45 Belongs to the globin family - - - 0.00000000000000000000000000000000000001693 150.0
HKD2_k127_6437934_46 ketosteroid isomerase - - - 0.00000000000000000000000000000242 132.0
HKD2_k127_6437934_47 YMGG-like Gly-zipper - - - 0.00000000000000000000000253 108.0
HKD2_k127_6437934_48 Redoxin - - - 0.00000000000000000004927 93.0
HKD2_k127_6437934_49 - - - - 0.0000000000000001852 86.0
HKD2_k127_6437934_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 605.0
HKD2_k127_6437934_50 efflux transmembrane transporter activity - - - 0.000000000000007939 81.0
HKD2_k127_6437934_51 Alpha beta hydrolase K01066 - - 0.0000000000002133 76.0
HKD2_k127_6437934_53 Redoxin - - - 0.00000000008326 66.0
HKD2_k127_6437934_54 efflux transmembrane transporter activity - - - 0.000000001012 66.0
HKD2_k127_6437934_55 - - - - 0.0001627 53.0
HKD2_k127_6437934_6 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 547.0
HKD2_k127_6437934_7 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 526.0
HKD2_k127_6437934_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 507.0
HKD2_k127_6437934_9 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 495.0
HKD2_k127_6462258_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1145.0
HKD2_k127_6462258_1 alpha-glucuronidase activity K01235 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886 3.2.1.139 0.0 1082.0
HKD2_k127_6462258_10 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 289.0
HKD2_k127_6462258_2 GlcNAc-PI de-N-acetylase - - - 1.155e-237 770.0
HKD2_k127_6462258_3 xylulokinase activity K00848,K00854 - 2.7.1.17,2.7.1.5 5.928e-231 725.0
HKD2_k127_6462258_4 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 2.169e-225 703.0
HKD2_k127_6462258_5 ABC transporter K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 599.0
HKD2_k127_6462258_6 transmembrane transporter activity K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 571.0
HKD2_k127_6462258_7 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 545.0
HKD2_k127_6462258_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 430.0
HKD2_k127_6462258_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 359.0
HKD2_k127_64718_0 FAD dependent oxidoreductase - - - 1.435e-214 679.0
HKD2_k127_64718_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 452.0
HKD2_k127_64718_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 411.0
HKD2_k127_64718_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 423.0
HKD2_k127_64718_5 23S rRNA-intervening sequence protein - - - 0.00001112 54.0
HKD2_k127_64718_6 S23 ribosomal protein - - - 0.00004705 51.0
HKD2_k127_6475190_0 Sortilin, neurotensin receptor 3, - - - 0.0 1312.0
HKD2_k127_6475190_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1105.0
HKD2_k127_6475190_10 Glycine D-amino acid oxidase (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 578.0
HKD2_k127_6475190_11 Beta-eliminating lyase K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 535.0
HKD2_k127_6475190_12 4-alpha-glucanotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 495.0
HKD2_k127_6475190_13 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 418.0
HKD2_k127_6475190_14 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 392.0
HKD2_k127_6475190_15 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 365.0
HKD2_k127_6475190_16 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
HKD2_k127_6475190_17 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 307.0
HKD2_k127_6475190_18 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000202 293.0
HKD2_k127_6475190_19 trehalose biosynthetic process K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000129 296.0
HKD2_k127_6475190_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1103.0
HKD2_k127_6475190_20 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
HKD2_k127_6475190_21 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HKD2_k127_6475190_22 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
HKD2_k127_6475190_23 dTDP-4-dehydrorhamnose reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 265.0
HKD2_k127_6475190_24 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002749 275.0
HKD2_k127_6475190_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001551 265.0
HKD2_k127_6475190_26 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004681 267.0
HKD2_k127_6475190_27 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000003942 236.0
HKD2_k127_6475190_29 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000002925 225.0
HKD2_k127_6475190_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.636e-308 957.0
HKD2_k127_6475190_30 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000000000000000000002122 215.0
HKD2_k127_6475190_31 MerR family regulatory protein K19591 - - 0.0000000000000000000000000000000000000000000000000000000008825 222.0
HKD2_k127_6475190_32 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000001845 209.0
HKD2_k127_6475190_33 peptidase S8 - - - 0.00000000000000000000000000000000000000000000000000003543 204.0
HKD2_k127_6475190_34 Putative lumazine-binding - - - 0.0000000000000000000000000000000000000000001045 166.0
HKD2_k127_6475190_35 - - - - 0.0000000000000000000000000000000000000000001158 163.0
HKD2_k127_6475190_36 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000005108 170.0
HKD2_k127_6475190_37 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000698 153.0
HKD2_k127_6475190_38 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000006182 157.0
HKD2_k127_6475190_39 polysaccharide export K01991 - - 0.0000000000000000000000000000000005794 139.0
HKD2_k127_6475190_4 hydrolase activity, hydrolyzing O-glycosyl compounds K05343 - 3.2.1.1,5.4.99.16 8.942e-297 917.0
HKD2_k127_6475190_40 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000002061 132.0
HKD2_k127_6475190_41 - - - - 0.000000000000000000000000000009507 126.0
HKD2_k127_6475190_42 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000001109 114.0
HKD2_k127_6475190_5 Domain of unknown function (DUF5117) - - - 1.378e-257 833.0
HKD2_k127_6475190_6 Carbohydrate phosphorylase K00688 - 2.4.1.1 4.044e-246 771.0
HKD2_k127_6475190_7 Domain of unknown function (DUF3416) K16147 - 2.4.99.16 9.049e-210 674.0
HKD2_k127_6475190_8 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 1.603e-209 686.0
HKD2_k127_6475190_9 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 635.0
HKD2_k127_6489692_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 512.0
HKD2_k127_6489692_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 475.0
HKD2_k127_6489692_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 419.0
HKD2_k127_6489692_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
HKD2_k127_6489692_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 363.0
HKD2_k127_6489692_5 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 364.0
HKD2_k127_6489692_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 352.0
HKD2_k127_6489692_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 346.0
HKD2_k127_6489692_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 308.0
HKD2_k127_6489692_9 - - - - 0.000000009759 62.0
HKD2_k127_6507642_0 peptidyl-tyrosine sulfation - - - 8.749e-265 832.0
HKD2_k127_6507642_1 Putative glucoamylase - - - 8.93e-228 713.0
HKD2_k127_6507642_10 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000005137 182.0
HKD2_k127_6507642_11 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000002234 143.0
HKD2_k127_6507642_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000004371 126.0
HKD2_k127_6507642_14 hydroperoxide reductase activity - - - 0.0000000000000000000000000000731 122.0
HKD2_k127_6507642_16 - - - - 0.0000000000000000000000009137 121.0
HKD2_k127_6507642_17 - - - - 0.00000000001961 76.0
HKD2_k127_6507642_2 peptidyl-tyrosine sulfation - - - 2.807e-225 725.0
HKD2_k127_6507642_3 sigma factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 551.0
HKD2_k127_6507642_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 554.0
HKD2_k127_6507642_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 360.0
HKD2_k127_6507642_6 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 351.0
HKD2_k127_6507642_7 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 302.0
HKD2_k127_6507642_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 310.0
HKD2_k127_6507642_9 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000001109 212.0
HKD2_k127_6517299_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 8.551e-219 692.0
HKD2_k127_6517299_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 474.0
HKD2_k127_6517299_10 Sigma-70 region 2 K03088 - - 0.0000000000000000000000001835 111.0
HKD2_k127_6517299_11 Protein conserved in bacteria - - - 0.000000000000002156 90.0
HKD2_k127_6517299_12 Domain of Unknown Function (DUF350) - - - 0.00000000007678 66.0
HKD2_k127_6517299_13 Carboxypeptidase regulatory-like domain - - - 0.0000000002452 75.0
HKD2_k127_6517299_14 - - - - 0.0000000005323 64.0
HKD2_k127_6517299_15 - - - - 0.0000002981 59.0
HKD2_k127_6517299_2 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 444.0
HKD2_k127_6517299_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 396.0
HKD2_k127_6517299_4 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 396.0
HKD2_k127_6517299_5 Helix-turn-helix domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 352.0
HKD2_k127_6517299_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 335.0
HKD2_k127_6517299_7 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003436 260.0
HKD2_k127_6517299_8 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000000000003913 139.0
HKD2_k127_6517299_9 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000004006 147.0
HKD2_k127_6541409_0 Sortilin, neurotensin receptor 3, - - - 0.0 1400.0
HKD2_k127_6541409_1 siderophore transport K02014 - - 0.0 1114.0
HKD2_k127_6541409_2 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 1.905e-309 956.0
HKD2_k127_6541409_3 N-acetyldiaminopimelate deacetylase activity K12941 - - 1.28e-224 709.0
HKD2_k127_6541409_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 508.0
HKD2_k127_6541409_5 homoserine kinase K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000002885 213.0
HKD2_k127_6569591_0 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000002993 169.0
HKD2_k127_6569591_1 Type II secretion system K02455 - - 0.000000000000000000000000000000000000002379 162.0
HKD2_k127_6569591_2 Type II secretion system (T2SS), protein E, N-terminal domain K02243,K02652 - - 0.0000000000000000000000000000000000001776 145.0
HKD2_k127_6569591_3 Type II secretion system (T2SS), protein K K02460 - - 0.00000004386 66.0
HKD2_k127_6580388_0 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 593.0
HKD2_k127_6580388_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 584.0
HKD2_k127_6580388_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 577.0
HKD2_k127_6580388_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 303.0
HKD2_k127_6580388_4 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000009089 211.0
HKD2_k127_6580388_5 Autotransporter beta-domain - - - 0.00001451 55.0
HKD2_k127_6599810_0 Zinc carboxypeptidase - - - 0.0 1136.0
HKD2_k127_6599810_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 383.0
HKD2_k127_6599810_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003092 282.0
HKD2_k127_6635231_0 Proprotein convertase P-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 581.0
HKD2_k127_6635231_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 382.0
HKD2_k127_6635231_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000004328 228.0
HKD2_k127_6635231_3 AAA ATPase domain - - - 0.0000001142 59.0
HKD2_k127_6635231_4 Putative restriction endonuclease - - - 0.00003433 48.0
HKD2_k127_6667122_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1451.0
HKD2_k127_6667122_1 COG0433 Predicted ATPase K06915 - - 5e-324 1001.0
HKD2_k127_6667122_10 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
HKD2_k127_6667122_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 489.0
HKD2_k127_6667122_12 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 494.0
HKD2_k127_6667122_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 473.0
HKD2_k127_6667122_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 439.0
HKD2_k127_6667122_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 413.0
HKD2_k127_6667122_16 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 408.0
HKD2_k127_6667122_17 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 349.0
HKD2_k127_6667122_18 COGs COG2380 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 340.0
HKD2_k127_6667122_19 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 335.0
HKD2_k127_6667122_2 AAA domain K03546 - - 1.222e-262 831.0
HKD2_k127_6667122_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 318.0
HKD2_k127_6667122_21 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 301.0
HKD2_k127_6667122_22 Glycosyl transferase family 2 K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 289.0
HKD2_k127_6667122_23 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 289.0
HKD2_k127_6667122_24 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003805 279.0
HKD2_k127_6667122_25 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
HKD2_k127_6667122_26 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 268.0
HKD2_k127_6667122_27 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 259.0
HKD2_k127_6667122_28 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
HKD2_k127_6667122_29 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
HKD2_k127_6667122_3 MacB-like periplasmic core domain - - - 2.064e-244 782.0
HKD2_k127_6667122_30 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003884 248.0
HKD2_k127_6667122_31 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000001608 220.0
HKD2_k127_6667122_32 PFAM O-methyltransferase, family 3 K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000004431 208.0
HKD2_k127_6667122_33 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000004198 187.0
HKD2_k127_6667122_34 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000002087 178.0
HKD2_k127_6667122_35 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000001905 183.0
HKD2_k127_6667122_36 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000004505 173.0
HKD2_k127_6667122_37 - - - - 0.000000000000000000000000000000000000001334 154.0
HKD2_k127_6667122_39 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000004225 133.0
HKD2_k127_6667122_4 POT family K03305 - - 2.606e-214 676.0
HKD2_k127_6667122_40 - - - - 0.0000000000000000000000000000004955 130.0
HKD2_k127_6667122_41 - - - - 0.0000000000000000000000000001257 127.0
HKD2_k127_6667122_42 Carboxypeptidase regulatory-like domain - - - 0.00000000000000001587 86.0
HKD2_k127_6667122_5 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 580.0
HKD2_k127_6667122_6 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 558.0
HKD2_k127_6667122_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HKD2_k127_6667122_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 539.0
HKD2_k127_6667122_9 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 524.0
HKD2_k127_6688031_0 efflux transmembrane transporter activity - - - 1.991e-291 918.0
HKD2_k127_6688031_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 589.0
HKD2_k127_6688031_10 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000001482 70.0
HKD2_k127_6688031_11 - - - - 0.00000002167 65.0
HKD2_k127_6688031_2 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 593.0
HKD2_k127_6688031_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 304.0
HKD2_k127_6688031_4 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 293.0
HKD2_k127_6688031_5 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000006898 232.0
HKD2_k127_6688031_6 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000001659 199.0
HKD2_k127_6688031_7 Single Cache domain 2 K07647 - 2.7.13.3 0.000000000000000000000000000000000000000000000005206 193.0
HKD2_k127_6688031_8 SnoaL-like domain - - - 0.00000000000000000000000000003375 123.0
HKD2_k127_6688031_9 Domain of unknown function (DUF4442) - - - 0.0000000000000000000001675 99.0
HKD2_k127_6718670_0 Glycogen debranching enzyme - - - 0.0 1287.0
HKD2_k127_6718670_1 carbohydrate binding K21298 - 2.4.1.333 0.0 1204.0
HKD2_k127_6718670_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 304.0
HKD2_k127_677585_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 451.0
HKD2_k127_677585_1 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 423.0
HKD2_k127_677585_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000002078 137.0
HKD2_k127_677585_4 SusD family K21572 - - 0.000003097 59.0
HKD2_k127_677585_5 Copper binding proteins, plastocyanin/azurin family - - - 0.00002192 55.0
HKD2_k127_6785616_0 Sortilin, neurotensin receptor 3, - - - 0.0 1336.0
HKD2_k127_6785616_1 TonB dependent receptor K02014 - - 1.986e-201 649.0
HKD2_k127_6785616_10 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 507.0
HKD2_k127_6785616_11 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009973 460.0
HKD2_k127_6785616_12 chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 439.0
HKD2_k127_6785616_13 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 345.0
HKD2_k127_6785616_14 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 338.0
HKD2_k127_6785616_15 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 340.0
HKD2_k127_6785616_16 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 317.0
HKD2_k127_6785616_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 316.0
HKD2_k127_6785616_18 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 298.0
HKD2_k127_6785616_19 ErfK ybiS ycfS ynhG family protein K19234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
HKD2_k127_6785616_2 Amidase K01426 - 3.5.1.4 3.921e-201 644.0
HKD2_k127_6785616_20 phosphorelay signal transduction system K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000004315 242.0
HKD2_k127_6785616_21 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
HKD2_k127_6785616_22 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HKD2_k127_6785616_23 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000000000000000001577 218.0
HKD2_k127_6785616_24 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000004582 212.0
HKD2_k127_6785616_25 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000005944 189.0
HKD2_k127_6785616_26 Nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000009579 179.0
HKD2_k127_6785616_27 - K09700 - - 0.0000000000000000000000000000000000000000001905 162.0
HKD2_k127_6785616_28 Histidine kinase - - - 0.000000000000000000000000000000000000000394 167.0
HKD2_k127_6785616_29 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00220,K00800 - 1.3.1.12,1.3.1.43,2.5.1.19 0.0000000000000000000000000000002824 137.0
HKD2_k127_6785616_3 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 591.0
HKD2_k127_6785616_30 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000003554 126.0
HKD2_k127_6785616_31 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001225 122.0
HKD2_k127_6785616_32 Protein of unknown function (DUF1634) - - - 0.00000000000000000000000001507 115.0
HKD2_k127_6785616_33 Outer membrane efflux protein - - - 0.000000000000000000000001059 106.0
HKD2_k127_6785616_34 - - - - 0.0000000000000000000004243 101.0
HKD2_k127_6785616_35 Protein of unknown function (DUF1569) - - - 0.000000000000000000006145 101.0
HKD2_k127_6785616_37 - - - - 0.00000000000001093 84.0
HKD2_k127_6785616_38 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000003702 67.0
HKD2_k127_6785616_39 phosphate-selective porin O and P - - - 0.0000000003713 72.0
HKD2_k127_6785616_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 591.0
HKD2_k127_6785616_40 Chorismate mutase type II K04516 - 5.4.99.5 0.00000002131 61.0
HKD2_k127_6785616_5 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 549.0
HKD2_k127_6785616_6 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 530.0
HKD2_k127_6785616_7 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 520.0
HKD2_k127_6785616_8 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 516.0
HKD2_k127_6785616_9 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 528.0
HKD2_k127_6803158_0 belongs to the thioredoxin family K20543 - - 1.162e-295 926.0
HKD2_k127_6803158_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.151e-198 629.0
HKD2_k127_6803158_10 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 398.0
HKD2_k127_6803158_11 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 342.0
HKD2_k127_6803158_12 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 312.0
HKD2_k127_6803158_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
HKD2_k127_6803158_14 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 303.0
HKD2_k127_6803158_15 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 293.0
HKD2_k127_6803158_16 PFAM glycoside hydrolase, family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003638 285.0
HKD2_k127_6803158_17 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
HKD2_k127_6803158_18 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006104 253.0
HKD2_k127_6803158_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
HKD2_k127_6803158_2 COG2303 Choline dehydrogenase and related flavoproteins K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 623.0
HKD2_k127_6803158_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
HKD2_k127_6803158_21 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
HKD2_k127_6803158_22 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000135 220.0
HKD2_k127_6803158_23 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003567 243.0
HKD2_k127_6803158_24 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001207 206.0
HKD2_k127_6803158_25 PFAM GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000001294 204.0
HKD2_k127_6803158_26 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000001646 205.0
HKD2_k127_6803158_27 acetyltransferase K22441 - 2.3.1.57 0.000000000000000000000000000000000000000000000000006023 187.0
HKD2_k127_6803158_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002081 183.0
HKD2_k127_6803158_3 ThiF family K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 562.0
HKD2_k127_6803158_30 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000001387 178.0
HKD2_k127_6803158_31 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000001018 197.0
HKD2_k127_6803158_32 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000001712 179.0
HKD2_k127_6803158_33 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000003609 169.0
HKD2_k127_6803158_34 DinB family - - - 0.00000000000000000000000000000000000000000006281 166.0
HKD2_k127_6803158_35 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000004511 162.0
HKD2_k127_6803158_36 YjbR - - - 0.000000000000000000000000000000000000000001259 160.0
HKD2_k127_6803158_37 acetyltransferase K03827 - - 0.000000000000000000000000000000000000000003758 160.0
HKD2_k127_6803158_38 - - - - 0.00000000000000000000000000000000000000001033 173.0
HKD2_k127_6803158_39 Protein of unknown function, DUF481 K07283 - - 0.00000000000000000000000000000000000000001798 162.0
HKD2_k127_6803158_4 Glycosyl hydrolase family 30 beta sandwich domain K01201 - 3.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 565.0
HKD2_k127_6803158_40 PFAM DsrE DsrF-like family K09004 - - 0.000000000000000000000000000000000000154 145.0
HKD2_k127_6803158_41 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000001238 145.0
HKD2_k127_6803158_42 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000001952 139.0
HKD2_k127_6803158_43 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000003296 133.0
HKD2_k127_6803158_44 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000001472 130.0
HKD2_k127_6803158_45 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000004112 129.0
HKD2_k127_6803158_46 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000002026 123.0
HKD2_k127_6803158_48 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004576 116.0
HKD2_k127_6803158_49 Domain of unknown function (DUF1508) K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000007697 114.0
HKD2_k127_6803158_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 529.0
HKD2_k127_6803158_50 hydroperoxide reductase activity - - - 0.0000000000000000000000007518 105.0
HKD2_k127_6803158_51 - - - - 0.0000000000000000000000027 109.0
HKD2_k127_6803158_52 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000006319 110.0
HKD2_k127_6803158_53 domain, Protein - - - 0.00000000000000000000112 109.0
HKD2_k127_6803158_54 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000007763 95.0
HKD2_k127_6803158_55 phospho-2-dehydro-3-deoxyheptonate aldolase - - - 0.00000000000000001285 88.0
HKD2_k127_6803158_56 Poly(ADP-ribose) polymerase catalytic domain K10799 GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000723,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042393,GO:0042592,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901360,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252 2.4.2.30 0.000000000000003142 87.0
HKD2_k127_6803158_58 - - - - 0.00000000001645 68.0
HKD2_k127_6803158_59 lactoylglutathione lyase activity - - - 0.00000003199 62.0
HKD2_k127_6803158_6 beta-1,4-mannooligosaccharide phosphorylase K21065 - 3.2.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 437.0
HKD2_k127_6803158_60 Serine aminopeptidase, S33 K01055,K10216,K18092 - 3.1.1.24,3.7.1.9 0.0000001309 60.0
HKD2_k127_6803158_61 Predicted membrane protein (DUF2339) - - - 0.000001888 61.0
HKD2_k127_6803158_62 - - - - 0.00004407 50.0
HKD2_k127_6803158_63 - - - - 0.0001091 49.0
HKD2_k127_6803158_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 441.0
HKD2_k127_6803158_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 403.0
HKD2_k127_6803158_9 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 384.0
HKD2_k127_6824298_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.417e-219 727.0
HKD2_k127_6824298_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 583.0
HKD2_k127_6824298_10 - - - - 0.00000000000001992 75.0
HKD2_k127_6824298_11 cell adhesion involved in biofilm formation - - - 0.00002817 57.0
HKD2_k127_6824298_2 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 515.0
HKD2_k127_6824298_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
HKD2_k127_6824298_4 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 393.0
HKD2_k127_6824298_5 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 353.0
HKD2_k127_6824298_6 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 324.0
HKD2_k127_6824298_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 324.0
HKD2_k127_6824298_8 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 317.0
HKD2_k127_6824298_9 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000001205 255.0
HKD2_k127_6873801_0 Sortilin, neurotensin receptor 3, - - - 0.0 1667.0
HKD2_k127_6873801_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1392.0
HKD2_k127_6873801_10 FES K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002525 282.0
HKD2_k127_6873801_11 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
HKD2_k127_6873801_12 PFAM Cache K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000169 242.0
HKD2_k127_6873801_13 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000002918 213.0
HKD2_k127_6873801_14 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000000000000000000000000000000000000000000000000009523 196.0
HKD2_k127_6873801_15 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000004583 176.0
HKD2_k127_6873801_16 Ubiquinol--cytochrome c reductase - - - 0.00000000000000000000000000000000000000000000487 173.0
HKD2_k127_6873801_18 copper resistance D domain protein K14166 - - 0.000000000000000000000000000007185 136.0
HKD2_k127_6873801_19 membrane K15977 - - 0.000000000000000000000000001629 124.0
HKD2_k127_6873801_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 8.655e-289 900.0
HKD2_k127_6873801_20 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000002243 112.0
HKD2_k127_6873801_21 NUDIX domain K00077,K01092,K03574,K03795 - 1.1.1.169,3.1.3.25,3.6.1.55,4.99.1.3 0.000000000000000000008461 99.0
HKD2_k127_6873801_22 DUF167 K09131 - - 0.00000000000000007426 91.0
HKD2_k127_6873801_23 transmembrane signaling receptor activity K03406 - - 0.00000001289 68.0
HKD2_k127_6873801_24 - - - - 0.000006916 54.0
HKD2_k127_6873801_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 2.615e-249 776.0
HKD2_k127_6873801_4 von Willebrand factor (vWF) type A domain - - - 8.25e-219 686.0
HKD2_k127_6873801_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 543.0
HKD2_k127_6873801_6 peptidase S9 prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 553.0
HKD2_k127_6873801_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 392.0
HKD2_k127_6873801_8 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 355.0
HKD2_k127_6873801_9 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 323.0
HKD2_k127_6955850_0 Hydrolase Family 16 - - - 1.726e-232 732.0
HKD2_k127_6955850_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 332.0
HKD2_k127_6955850_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 306.0
HKD2_k127_6955850_3 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000004118 214.0
HKD2_k127_6955850_4 helix_turn_helix, Deoxyribose operon repressor - - - 0.0000000000000000000000000000000000000000000001573 177.0
HKD2_k127_6955850_5 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000003404 150.0
HKD2_k127_6955850_6 - - - - 0.0000000000000000000000000000001524 131.0
HKD2_k127_6955850_8 - - - - 0.00000000007948 67.0
HKD2_k127_6955850_9 heat shock protein binding - - - 0.0000000211 61.0
HKD2_k127_6996235_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 9.021e-282 881.0
HKD2_k127_6996235_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 8.714e-235 730.0
HKD2_k127_6996235_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002045 285.0
HKD2_k127_6996235_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 260.0
HKD2_k127_6996235_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000001694 237.0
HKD2_k127_6996235_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003652 224.0
HKD2_k127_6996235_14 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000003512 228.0
HKD2_k127_6996235_15 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000002819 210.0
HKD2_k127_6996235_16 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000005251 192.0
HKD2_k127_6996235_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000007882 183.0
HKD2_k127_6996235_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000001566 172.0
HKD2_k127_6996235_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000003099 169.0
HKD2_k127_6996235_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.608e-204 644.0
HKD2_k127_6996235_20 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001993 165.0
HKD2_k127_6996235_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000001143 160.0
HKD2_k127_6996235_22 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000000002141 153.0
HKD2_k127_6996235_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000008309 147.0
HKD2_k127_6996235_24 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000007276 147.0
HKD2_k127_6996235_25 Ribosomal protein L30p/L7e K02907 - - 0.00000000000000000000000000001572 128.0
HKD2_k127_6996235_26 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004276 104.0
HKD2_k127_6996235_27 Ribosomal L29 protein K02904 - - 0.0000000000000003117 81.0
HKD2_k127_6996235_28 PFAM blue (type 1) copper domain protein - - - 0.000001064 60.0
HKD2_k127_6996235_29 TonB dependent receptor - - - 0.00002518 55.0
HKD2_k127_6996235_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 479.0
HKD2_k127_6996235_30 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0003443 44.0
HKD2_k127_6996235_4 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
HKD2_k127_6996235_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 374.0
HKD2_k127_6996235_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 320.0
HKD2_k127_6996235_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 317.0
HKD2_k127_6996235_8 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 312.0
HKD2_k127_6996235_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 283.0
HKD2_k127_7007938_0 FtsX-like permease family K02004 - - 2.303e-208 674.0
HKD2_k127_7007938_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 436.0
HKD2_k127_7007938_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
HKD2_k127_7007938_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 275.0
HKD2_k127_7007938_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003931 263.0
HKD2_k127_7020090_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.026e-235 730.0
HKD2_k127_7020090_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 525.0
HKD2_k127_7020090_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 322.0
HKD2_k127_7020090_3 pilus organization K07346 - - 0.0000000000000000000000000000000000000000001032 170.0
HKD2_k127_7020090_4 - - - - 0.000000000000001252 85.0
HKD2_k127_7061244_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 567.0
HKD2_k127_7061244_1 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 515.0
HKD2_k127_7061244_2 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 455.0
HKD2_k127_7061244_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 399.0
HKD2_k127_7061244_4 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 392.0
HKD2_k127_7061244_5 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 375.0
HKD2_k127_7061244_6 DNA recombination - GO:0001101,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009269,GO:0009314,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010212,GO:0010332,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042631,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071465,GO:0071478,GO:0071479,GO:0071480,GO:0071496,GO:0071704,GO:0090304,GO:0104004,GO:1901360,GO:1901700,GO:1901701 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 347.0
HKD2_k127_7061244_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000009463 248.0
HKD2_k127_7103644_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.727e-314 981.0
HKD2_k127_7103644_1 Putative modulator of DNA gyrase K03568 - - 1.913e-239 752.0
HKD2_k127_7103644_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 482.0
HKD2_k127_7103644_11 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 432.0
HKD2_k127_7103644_12 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 421.0
HKD2_k127_7103644_13 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 411.0
HKD2_k127_7103644_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 381.0
HKD2_k127_7103644_15 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 368.0
HKD2_k127_7103644_16 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 325.0
HKD2_k127_7103644_17 PglZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 313.0
HKD2_k127_7103644_18 zinc ion binding K04477,K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 301.0
HKD2_k127_7103644_19 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 293.0
HKD2_k127_7103644_2 ABC transporter transmembrane region K11085 - - 2.981e-218 692.0
HKD2_k127_7103644_20 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001208 282.0
HKD2_k127_7103644_21 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001803 279.0
HKD2_k127_7103644_22 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004058 263.0
HKD2_k127_7103644_23 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000001479 253.0
HKD2_k127_7103644_24 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005382 258.0
HKD2_k127_7103644_25 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000002692 224.0
HKD2_k127_7103644_26 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000002418 211.0
HKD2_k127_7103644_27 - - - - 0.0000000000000000000000000000000000000002502 159.0
HKD2_k127_7103644_3 Sigma-54 interaction domain - - - 1.203e-215 677.0
HKD2_k127_7103644_30 Outer membrane protein beta-barrel domain - - - 0.000000000000002894 85.0
HKD2_k127_7103644_31 Outer membrane protein beta-barrel domain - - - 0.0000000000001052 81.0
HKD2_k127_7103644_32 - - - - 0.00000000000142 75.0
HKD2_k127_7103644_4 Beta-eliminating lyase K00639 - 2.3.1.29 2.665e-203 639.0
HKD2_k127_7103644_5 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 612.0
HKD2_k127_7103644_6 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 577.0
HKD2_k127_7103644_7 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 563.0
HKD2_k127_7103644_8 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 542.0
HKD2_k127_7103644_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 503.0
HKD2_k127_7151192_0 Zinc carboxypeptidase - - - 9.635e-283 898.0
HKD2_k127_7151192_1 TonB dependent receptor - - - 4.752e-257 831.0
HKD2_k127_7151192_10 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002881 260.0
HKD2_k127_7151192_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003278 258.0
HKD2_k127_7151192_12 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000003056 263.0
HKD2_k127_7151192_13 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000001074 207.0
HKD2_k127_7151192_2 Dienelactone hydrolase family - - - 1.262e-215 705.0
HKD2_k127_7151192_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 565.0
HKD2_k127_7151192_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 509.0
HKD2_k127_7151192_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 382.0
HKD2_k127_7151192_6 Inositol monophosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 348.0
HKD2_k127_7151192_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 339.0
HKD2_k127_7151192_8 - K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 326.0
HKD2_k127_7151192_9 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004606 281.0
HKD2_k127_7377618_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1176.0
HKD2_k127_7377618_1 TonB dependent receptor - - - 1.513e-234 760.0
HKD2_k127_7377618_2 beta-galactosidase activity K05970 - 3.1.1.53 6.822e-195 622.0
HKD2_k127_7377618_3 Aminotransferase K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 336.0
HKD2_k127_7377618_4 MFS/sugar transport protein K03292 - - 0.00000002672 55.0
HKD2_k127_7461118_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.037e-316 978.0
HKD2_k127_7461118_1 efflux transmembrane transporter activity - - - 2.206e-223 720.0
HKD2_k127_7461118_10 FRG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 334.0
HKD2_k127_7461118_11 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 321.0
HKD2_k127_7461118_12 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004747 246.0
HKD2_k127_7461118_13 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 238.0
HKD2_k127_7461118_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002654 235.0
HKD2_k127_7461118_15 Putative adhesin - - - 0.00000000000000000000000000000000000000000000000000000006864 208.0
HKD2_k127_7461118_16 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
HKD2_k127_7461118_17 Haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000004816 194.0
HKD2_k127_7461118_18 - - - - 0.0000000000000000000000000000000000000000004244 163.0
HKD2_k127_7461118_19 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000006428 157.0
HKD2_k127_7461118_2 Helix-hairpin-helix motif K14162 - 2.7.7.7 1.317e-196 651.0
HKD2_k127_7461118_20 - - - - 0.000000000000000000000000000000000002988 149.0
HKD2_k127_7461118_21 Barstar (barnase inhibitor) - - - 0.000000000000000000000000000000000005711 143.0
HKD2_k127_7461118_22 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000000001493 136.0
HKD2_k127_7461118_23 protein homotetramerization - - - 0.000000000000000000000000000000002198 139.0
HKD2_k127_7461118_24 PFAM GlcNAc-PI de-N-acetylase K22135 - - 0.000000000000000000000000000000007503 136.0
HKD2_k127_7461118_25 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000000001656 132.0
HKD2_k127_7461118_26 - - - - 0.00000000000000000000000000000005555 136.0
HKD2_k127_7461118_27 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000002149 125.0
HKD2_k127_7461118_28 - - - - 0.000000000000000000000000000001388 127.0
HKD2_k127_7461118_29 - - - - 0.00000000000000000000000002206 113.0
HKD2_k127_7461118_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 572.0
HKD2_k127_7461118_30 - - - - 0.000000000000000006731 94.0
HKD2_k127_7461118_31 Flavin containing amine oxidoreductase - - - 0.0000000000008535 73.0
HKD2_k127_7461118_32 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000002371 73.0
HKD2_k127_7461118_33 energy transducer activity K03832 - - 0.0000000006638 71.0
HKD2_k127_7461118_34 Rad51 - - - 0.000000003017 67.0
HKD2_k127_7461118_35 - - - - 0.000000003201 64.0
HKD2_k127_7461118_36 Acid phosphatase homologues - - - 0.0000003776 62.0
HKD2_k127_7461118_37 Flavin containing amine oxidoreductase - - - 0.000404 47.0
HKD2_k127_7461118_4 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 454.0
HKD2_k127_7461118_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 413.0
HKD2_k127_7461118_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 413.0
HKD2_k127_7461118_7 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 391.0
HKD2_k127_7461118_8 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 374.0
HKD2_k127_7461118_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 342.0
HKD2_k127_750323_0 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 613.0
HKD2_k127_750323_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 502.0
HKD2_k127_750323_2 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 346.0
HKD2_k127_750323_3 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000008609 223.0
HKD2_k127_750323_4 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000001148 147.0
HKD2_k127_750323_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000006603 124.0
HKD2_k127_7572798_0 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1565.0
HKD2_k127_7572798_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.684e-305 948.0
HKD2_k127_7572798_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 536.0
HKD2_k127_7572798_11 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 518.0
HKD2_k127_7572798_12 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 499.0
HKD2_k127_7572798_13 regulation of response to stimulus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 455.0
HKD2_k127_7572798_14 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 427.0
HKD2_k127_7572798_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 369.0
HKD2_k127_7572798_16 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 337.0
HKD2_k127_7572798_17 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 308.0
HKD2_k127_7572798_18 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 308.0
HKD2_k127_7572798_2 copper-translocating P-type ATPase K01533 - 3.6.3.4 1.782e-283 889.0
HKD2_k127_7572798_20 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 251.0
HKD2_k127_7572798_21 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005519 239.0
HKD2_k127_7572798_22 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000811 207.0
HKD2_k127_7572798_23 sensor histidine kinase response - - - 0.000000000000000000000001599 116.0
HKD2_k127_7572798_24 SNARE associated Golgi protein - - - 0.00000000000000000000004341 107.0
HKD2_k127_7572798_25 Domain of unknown function (DUF4142) - - - 0.0000000001325 70.0
HKD2_k127_7572798_26 - - - - 0.0000000005091 72.0
HKD2_k127_7572798_27 V4R K07013 - - 0.0000235 53.0
HKD2_k127_7572798_3 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 3.14e-262 825.0
HKD2_k127_7572798_4 AMP-binding enzyme K01897 - 6.2.1.3 6.198e-256 803.0
HKD2_k127_7572798_5 Belongs to the glycosyl hydrolase 43 family - - - 1.323e-240 752.0
HKD2_k127_7572798_6 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 1.87e-203 642.0
HKD2_k127_7572798_7 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 621.0
HKD2_k127_7572798_8 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 581.0
HKD2_k127_7572798_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 554.0
HKD2_k127_7666309_0 Tricorn protease homolog K08676 - - 0.0 1452.0
HKD2_k127_7666309_1 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1100.0
HKD2_k127_7666309_10 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 9.981e-205 654.0
HKD2_k127_7666309_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 7.119e-204 648.0
HKD2_k127_7666309_12 hydrolase activity, hydrolyzing O-glycosyl compounds K00689 GO:0005575,GO:0005576 2.4.1.5 4.33e-201 647.0
HKD2_k127_7666309_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 601.0
HKD2_k127_7666309_14 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 597.0
HKD2_k127_7666309_15 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 586.0
HKD2_k127_7666309_16 Nucleoside H+ symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 559.0
HKD2_k127_7666309_17 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 571.0
HKD2_k127_7666309_18 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 522.0
HKD2_k127_7666309_19 PFAM peptidase M24 K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 470.0
HKD2_k127_7666309_2 Glutamine synthetase type III N terminal K01915 - 6.3.1.2 0.0 1075.0
HKD2_k127_7666309_20 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
HKD2_k127_7666309_21 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 433.0
HKD2_k127_7666309_22 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 398.0
HKD2_k127_7666309_23 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
HKD2_k127_7666309_24 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 322.0
HKD2_k127_7666309_25 PFAM Class II aldolase K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 311.0
HKD2_k127_7666309_26 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009601 290.0
HKD2_k127_7666309_27 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001007 263.0
HKD2_k127_7666309_28 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000000000000000000000000000000000000001858 261.0
HKD2_k127_7666309_29 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000001611 224.0
HKD2_k127_7666309_3 Involved in the tonB-independent uptake of proteins K03641 - - 3.425e-311 983.0
HKD2_k127_7666309_30 Bacteriocin-protection protein - - - 0.00000000000000000000000000000000000000000000000000000000212 208.0
HKD2_k127_7666309_31 - - - - 0.00000000000000000000000000000000000000000000000000002185 197.0
HKD2_k127_7666309_32 gluconokinase activity K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000007674 192.0
HKD2_k127_7666309_33 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000002135 189.0
HKD2_k127_7666309_34 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000000000001329 152.0
HKD2_k127_7666309_35 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001437 158.0
HKD2_k127_7666309_36 COG1247 Sortase and related acyltransferases K03823 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 2.3.1.183 0.0000000000000000000000000000000004451 137.0
HKD2_k127_7666309_38 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000405 123.0
HKD2_k127_7666309_39 Transglycosylase associated protein - - - 0.000000000000000000000000007666 113.0
HKD2_k127_7666309_4 GMC oxidoreductase - - - 3.089e-308 950.0
HKD2_k127_7666309_42 arabinan catabolic process K17624 - 3.2.1.97 0.000005312 50.0
HKD2_k127_7666309_43 Domain of Unknown Function (DUF350) - - - 0.0001162 50.0
HKD2_k127_7666309_5 Insulinase (Peptidase family M16) K07263 - - 1.824e-287 913.0
HKD2_k127_7666309_6 glucan 1,4-alpha-glucosidase activity - - - 3.658e-286 889.0
HKD2_k127_7666309_7 Dienelactone hydrolase family - - - 3.227e-284 894.0
HKD2_k127_7666309_8 aminopeptidase N - - - 2.241e-280 876.0
HKD2_k127_7666309_9 PFAM Carbohydrate kinase K00853 - 2.7.1.16 1.612e-244 767.0
HKD2_k127_7693066_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 1.683e-241 775.0
HKD2_k127_7693066_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 524.0
HKD2_k127_7693066_10 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000107 163.0
HKD2_k127_7693066_11 Prolyl oligopeptidase K01322 - 3.4.21.26 0.00000000000000000000000000000000000001013 145.0
HKD2_k127_7693066_12 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000009842 143.0
HKD2_k127_7693066_13 domain, Protein - - - 0.000000000000000000000000000958 120.0
HKD2_k127_7693066_14 cobalamin-transporting ATPase activity K02014,K16092 - - 0.0000000000000000000000204 117.0
HKD2_k127_7693066_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 335.0
HKD2_k127_7693066_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 308.0
HKD2_k127_7693066_4 Histidine kinase K07644,K18351 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 314.0
HKD2_k127_7693066_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004657 284.0
HKD2_k127_7693066_6 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000002093 254.0
HKD2_k127_7693066_7 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000001858 201.0
HKD2_k127_7693066_9 Bacterial virulence protein (VirJ) - - - 0.00000000000000000000000000000000000000000000009208 186.0
HKD2_k127_7707013_0 Major facilitator Superfamily K08369 - - 1.368e-217 687.0
HKD2_k127_7707013_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 467.0
HKD2_k127_7707013_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000002105 136.0
HKD2_k127_7721261_0 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 336.0
HKD2_k127_7721261_1 Uncharacterized conserved protein (COG2071) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 311.0
HKD2_k127_7721261_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008997 271.0
HKD2_k127_7721261_3 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000004289 221.0
HKD2_k127_7721261_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006887 224.0
HKD2_k127_7721261_5 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000002603 163.0
HKD2_k127_7721261_6 - - - - 0.0000000000000000000000000000000000000001342 160.0
HKD2_k127_7721261_7 cyclic nucleotide binding K10914,K21563 - - 0.0000000000000000000000000000000000000005941 158.0
HKD2_k127_7721261_8 Cyclic nucleotide-monophosphate binding domain - - - 0.0000006864 51.0
HKD2_k127_7721261_9 Protein of unknown function (DUF3828) - - - 0.0004218 51.0
HKD2_k127_7726280_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 7.458e-306 945.0
HKD2_k127_7726280_1 Peptidase family M28 - - - 1.026e-273 856.0
HKD2_k127_7726280_10 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 433.0
HKD2_k127_7726280_11 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 434.0
HKD2_k127_7726280_12 Polysaccharide biosynthesis protein K02473 - 5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 425.0
HKD2_k127_7726280_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 399.0
HKD2_k127_7726280_14 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 399.0
HKD2_k127_7726280_15 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 396.0
HKD2_k127_7726280_16 phosphopantetheine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
HKD2_k127_7726280_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 373.0
HKD2_k127_7726280_18 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 372.0
HKD2_k127_7726280_19 Protein of unknown function (DUF979) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 365.0
HKD2_k127_7726280_2 Multicopper oxidase K22348 - 1.16.3.3 8.146e-234 741.0
HKD2_k127_7726280_20 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 325.0
HKD2_k127_7726280_21 Protein of unknown function (DUF969) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
HKD2_k127_7726280_22 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000036 278.0
HKD2_k127_7726280_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000158 275.0
HKD2_k127_7726280_24 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006753 289.0
HKD2_k127_7726280_25 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000094 287.0
HKD2_k127_7726280_26 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000005164 251.0
HKD2_k127_7726280_27 guanyl-nucleotide exchange factor activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000007482 245.0
HKD2_k127_7726280_28 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000007188 231.0
HKD2_k127_7726280_29 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000000006366 228.0
HKD2_k127_7726280_3 lysine biosynthetic process via aminoadipic acid - - - 3.019e-233 746.0
HKD2_k127_7726280_30 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000003201 208.0
HKD2_k127_7726280_32 Copper chaperone PCu(A)C K03619,K07152,K09796 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.00000000000000000000000000000000000000000002652 171.0
HKD2_k127_7726280_33 protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000000009096 169.0
HKD2_k127_7726280_34 - - - - 0.00000000000000000000000000000000000000004481 156.0
HKD2_k127_7726280_35 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000002072 154.0
HKD2_k127_7726280_36 polysaccharide export - - - 0.000000000000000000000000001445 125.0
HKD2_k127_7726280_37 Histidine kinase - - - 0.0000000000000000009136 91.0
HKD2_k127_7726280_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 614.0
HKD2_k127_7726280_40 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000007102 69.0
HKD2_k127_7726280_41 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000898 66.0
HKD2_k127_7726280_5 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 575.0
HKD2_k127_7726280_6 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 580.0
HKD2_k127_7726280_7 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 529.0
HKD2_k127_7726280_8 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 519.0
HKD2_k127_7726280_9 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 475.0
HKD2_k127_7764621_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.021e-264 820.0
HKD2_k127_7764621_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 495.0
HKD2_k127_7764621_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 459.0
HKD2_k127_7764621_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 452.0
HKD2_k127_7764621_4 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 417.0
HKD2_k127_7764621_5 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 344.0
HKD2_k127_7764621_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 247.0
HKD2_k127_7766661_0 Tricorn protease PDZ domain K08676 - - 0.0 1068.0
HKD2_k127_7766661_1 carboxylic ester hydrolase activity K03929 - - 3.619e-269 836.0
HKD2_k127_7766661_10 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.0000001578 61.0
HKD2_k127_7766661_2 FMN-dependent dehydrogenase K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 542.0
HKD2_k127_7766661_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 364.0
HKD2_k127_7766661_4 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.0000000000000000000000000000000000001175 159.0
HKD2_k127_7766661_5 - - - - 0.000000000000000000000000000001418 136.0
HKD2_k127_7766661_7 Transcriptional regulator - - - 0.0000000000000000000007918 107.0
HKD2_k127_7766661_8 Sh3 type 3 domain protein - - - 0.0000000000001529 81.0
HKD2_k127_776809_0 DNA restriction-modification system - - - 2.821e-260 831.0
HKD2_k127_776809_1 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.000001952 52.0
HKD2_k127_7774643_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1034.0
HKD2_k127_7774643_1 protein histidine kinase activity K03407,K07678 - 2.7.13.3 7.142e-279 878.0
HKD2_k127_7774643_10 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 255.0
HKD2_k127_7774643_11 Domain of unknown function (DUF4249) - - - 0.000000000000000000000000000000000000000000000000000000000002307 224.0
HKD2_k127_7774643_12 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000137 169.0
HKD2_k127_7774643_14 - - - - 0.0000000000000000000002223 109.0
HKD2_k127_7774643_2 Carboxypeptidase regulatory-like domain - - - 6.172e-207 694.0
HKD2_k127_7774643_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 553.0
HKD2_k127_7774643_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 497.0
HKD2_k127_7774643_5 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 475.0
HKD2_k127_7774643_6 heat shock protein binding K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 439.0
HKD2_k127_7774643_7 Protein kinase domain K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 401.0
HKD2_k127_7774643_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 371.0
HKD2_k127_7774643_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 323.0
HKD2_k127_7806955_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.14e-241 754.0
HKD2_k127_7806955_1 ABC transporter K02056 - 3.6.3.17 1.036e-200 653.0
HKD2_k127_7806955_10 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 393.0
HKD2_k127_7806955_11 lipolytic protein G-D-S-L family K01126,K01181,K01186 - 3.1.4.46,3.2.1.18,3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 297.0
HKD2_k127_7806955_12 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000006043 232.0
HKD2_k127_7806955_13 ANTAR K22010 - - 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
HKD2_k127_7806955_14 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000003131 147.0
HKD2_k127_7806955_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 513.0
HKD2_k127_7806955_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 519.0
HKD2_k127_7806955_4 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 501.0
HKD2_k127_7806955_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 511.0
HKD2_k127_7806955_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 491.0
HKD2_k127_7806955_7 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 492.0
HKD2_k127_7806955_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
HKD2_k127_7806955_9 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 392.0
HKD2_k127_7826674_0 TonB-dependent receptor K02014 - - 3.244e-281 891.0
HKD2_k127_7826674_1 efflux transmembrane transporter activity - - - 6.93e-272 859.0
HKD2_k127_7826674_2 serine-type peptidase activity - - - 1.051e-240 768.0
HKD2_k127_7826674_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.65e-216 688.0
HKD2_k127_7826674_4 Amidohydrolase - - - 5.767e-214 669.0
HKD2_k127_7826674_5 Sigma-70 region 2 - - - 1.998e-198 626.0
HKD2_k127_7826674_6 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
HKD2_k127_7826674_7 Protein of unknown function (DUF3761) - - - 0.00002441 53.0
HKD2_k127_783185_0 Prolyl oligopeptidase family - - - 0.0 1249.0
HKD2_k127_783185_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.689e-277 867.0
HKD2_k127_783185_10 Squalene--hopene cyclase - - - 0.000000000000000000000000000000000000000008661 160.0
HKD2_k127_783185_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000002525 152.0
HKD2_k127_783185_12 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000008458 143.0
HKD2_k127_783185_13 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000003769 137.0
HKD2_k127_783185_14 negative regulation of transcription, DNA-templated - - - 0.0000000000000000000000000000002404 131.0
HKD2_k127_783185_15 - - - - 0.0000000000000000000000000007921 124.0
HKD2_k127_783185_16 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000001055 105.0
HKD2_k127_783185_17 acetyltransferase - - - 0.00000000000000000000005887 111.0
HKD2_k127_783185_18 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000001561 82.0
HKD2_k127_783185_19 Rhodanese Homology Domain - - - 0.0000000002616 68.0
HKD2_k127_783185_2 Major facilitator Superfamily K08178 - - 2.807e-196 620.0
HKD2_k127_783185_3 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 558.0
HKD2_k127_783185_4 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 576.0
HKD2_k127_783185_5 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
HKD2_k127_783185_6 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001498 275.0
HKD2_k127_783185_7 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000002137 208.0
HKD2_k127_783185_8 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000000000000000000000000000000000000000002412 194.0
HKD2_k127_783185_9 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000007803 189.0
HKD2_k127_7842644_0 Domain of unknown function (DUF5117) - - - 2.749e-294 915.0
HKD2_k127_7842644_1 Amidohydrolase family - - - 5.737e-249 780.0
HKD2_k127_7842644_2 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
HKD2_k127_7842644_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 443.0
HKD2_k127_7842644_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 423.0
HKD2_k127_7842644_5 Peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000002289 243.0
HKD2_k127_7842644_6 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000004285 131.0
HKD2_k127_7842644_7 Prokaryotic N-terminal methylation motif - - - 0.000000000009785 66.0
HKD2_k127_7866439_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 6.748e-255 822.0
HKD2_k127_7866439_1 alpha-galactosidase - - - 5.036e-237 751.0
HKD2_k127_7866439_10 BadF/BadG/BcrA/BcrD ATPase family K04114 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 482.0
HKD2_k127_7866439_11 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 464.0
HKD2_k127_7866439_12 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 462.0
HKD2_k127_7866439_13 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 432.0
HKD2_k127_7866439_14 benzoyl-CoA reductase K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 435.0
HKD2_k127_7866439_15 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009127 404.0
HKD2_k127_7866439_16 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 404.0
HKD2_k127_7866439_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 347.0
HKD2_k127_7866439_18 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 341.0
HKD2_k127_7866439_19 polyketide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 321.0
HKD2_k127_7866439_2 Sodium:solute symporter family - - - 7.46e-230 739.0
HKD2_k127_7866439_20 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 310.0
HKD2_k127_7866439_21 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 311.0
HKD2_k127_7866439_22 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000002678 270.0
HKD2_k127_7866439_23 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
HKD2_k127_7866439_24 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000006166 252.0
HKD2_k127_7866439_25 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002132 251.0
HKD2_k127_7866439_26 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000001032 208.0
HKD2_k127_7866439_27 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000001114 228.0
HKD2_k127_7866439_28 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000001051 213.0
HKD2_k127_7866439_3 PFAM Enoyl-CoA hydratase isomerase - - - 2.24e-215 691.0
HKD2_k127_7866439_30 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000001347 189.0
HKD2_k127_7866439_31 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000008183 174.0
HKD2_k127_7866439_32 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000009053 181.0
HKD2_k127_7866439_33 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000001547 172.0
HKD2_k127_7866439_34 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000313 156.0
HKD2_k127_7866439_35 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000007087 149.0
HKD2_k127_7866439_36 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000001488 134.0
HKD2_k127_7866439_37 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000001614 127.0
HKD2_k127_7866439_38 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000001438 126.0
HKD2_k127_7866439_39 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000001655 125.0
HKD2_k127_7866439_4 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 2.622e-205 655.0
HKD2_k127_7866439_40 AraC-like ligand binding domain - - - 0.0000000000000000000000000009166 115.0
HKD2_k127_7866439_41 UPF0182 protein K09118 - - 0.000000000000000000000000002257 123.0
HKD2_k127_7866439_42 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000002033 119.0
HKD2_k127_7866439_43 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000007711 79.0
HKD2_k127_7866439_44 metal cluster binding K06940,K18475 - - 0.00000000002681 72.0
HKD2_k127_7866439_45 Protein of unknown function (DUF2934) - - - 0.0002789 50.0
HKD2_k127_7866439_5 Peptidase dimerisation domain - - - 4.499e-202 643.0
HKD2_k127_7866439_6 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 3.043e-194 613.0
HKD2_k127_7866439_7 benzoyl-CoA reductase K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 595.0
HKD2_k127_7866439_8 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 600.0
HKD2_k127_7866439_9 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 515.0
HKD2_k127_7868935_0 LVIVD repeat - - - 1.951e-225 721.0
HKD2_k127_7868935_1 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000000000000001978 149.0
HKD2_k127_7868935_2 Helix-turn-helix domain - - - 0.000000000000000000000002434 113.0
HKD2_k127_7868935_3 phosphorelay signal transduction system - - - 0.0000000008996 67.0
HKD2_k127_7946892_0 Tetratricopeptide repeat K12132 - 2.7.11.1 1.651e-249 784.0
HKD2_k127_7946892_1 protein kinase activity - - - 0.0000000000000000000000000000000000000003479 169.0
HKD2_k127_7946892_2 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000003607 95.0
HKD2_k127_7952689_0 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 375.0
HKD2_k127_7952689_1 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 372.0
HKD2_k127_7952689_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 355.0
HKD2_k127_7952689_3 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.000000000000000000000000000000000000000000000000000008296 206.0
HKD2_k127_7952689_4 - - - - 0.00000000000000000000000000000001611 141.0
HKD2_k127_7952689_5 RDD family - - - 0.0000000000000000000000000000002668 134.0
HKD2_k127_7952689_6 - - - - 0.0000000000000000000000007883 118.0
HKD2_k127_7952689_8 Protein of unknown function (DUF3592) - - - 0.00000001013 67.0
HKD2_k127_7952689_9 Protein kinase domain K12132 - 2.7.11.1 0.00001688 53.0
HKD2_k127_7966401_0 efflux transmembrane transporter activity - - - 0.0 1395.0
HKD2_k127_7966401_1 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 487.0
HKD2_k127_7966401_2 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 358.0
HKD2_k127_7966401_3 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000000000000000000000961 182.0
HKD2_k127_7966401_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000003716 143.0
HKD2_k127_7966401_5 ABC transporter K01990 - - 0.000000000000000000000000003075 128.0
HKD2_k127_7966401_6 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000003477 99.0
HKD2_k127_7966401_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000003787 93.0
HKD2_k127_8010367_0 peptidyl-tyrosine sulfation - - - 0.0 1437.0
HKD2_k127_8010367_1 Bacterial transcriptional activator domain - - - 0.0 1129.0
HKD2_k127_8010367_2 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 5.684e-243 781.0
HKD2_k127_8010367_3 MFS/sugar transport protein K16211 - - 4.473e-221 696.0
HKD2_k127_8010367_4 hydrolase activity, hydrolyzing O-glycosyl compounds K01176 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.1 9.374e-202 645.0
HKD2_k127_8010367_5 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 465.0
HKD2_k127_8010367_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000009714 192.0
HKD2_k127_8010367_7 - - - - 0.0000000000000000000000000000000000000000002556 174.0
HKD2_k127_8010367_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000007438 57.0
HKD2_k127_8066671_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 507.0
HKD2_k127_8066671_1 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 457.0
HKD2_k127_8066671_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 267.0
HKD2_k127_8066671_3 Tetratricopeptide repeat - - - 0.00000000004702 76.0
HKD2_k127_8066671_4 KaiC - - - 0.0000007824 61.0
HKD2_k127_8091683_0 - - - - 0.0 1155.0
HKD2_k127_8091683_1 succinyl-diaminopimelate desuccinylase activity - - - 1.497e-196 623.0
HKD2_k127_8091683_10 Protein of unknown function (DUF3224) - - - 0.0000000000000000000000000000002413 136.0
HKD2_k127_8091683_11 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000001025 109.0
HKD2_k127_8091683_12 - - - - 0.00000000000000915 84.0
HKD2_k127_8091683_13 Protein of unknown function (DUF3592) - - - 0.000000003603 64.0
HKD2_k127_8091683_2 PFAM General substrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 550.0
HKD2_k127_8091683_3 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 455.0
HKD2_k127_8091683_4 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 426.0
HKD2_k127_8091683_5 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 354.0
HKD2_k127_8091683_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005014 298.0
HKD2_k127_8091683_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000001807 214.0
HKD2_k127_8091683_8 YCII-related domain - - - 0.000000000000000000000000000000000000000000007944 167.0
HKD2_k127_8091683_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000004363 140.0
HKD2_k127_8139692_0 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 542.0
HKD2_k127_8139692_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 524.0
HKD2_k127_8139692_10 Cupin domain - - - 0.00000000000000000000000000000000000000000000000001473 190.0
HKD2_k127_8139692_11 Protein of unknown function (DUF2878) - - - 0.0000000000000000000000000000000000000000001497 170.0
HKD2_k127_8139692_12 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000009789 161.0
HKD2_k127_8139692_13 membrane - - - 0.000000000000000000000000000000000000001178 152.0
HKD2_k127_8139692_14 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000001649 158.0
HKD2_k127_8139692_15 Protein of unknown function (DUF3606) - - - 0.000000000000006655 76.0
HKD2_k127_8139692_16 - - - - 0.00002943 54.0
HKD2_k127_8139692_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 470.0
HKD2_k127_8139692_3 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 429.0
HKD2_k127_8139692_4 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 294.0
HKD2_k127_8139692_5 LysR family transcription regulator protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 280.0
HKD2_k127_8139692_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008579 289.0
HKD2_k127_8139692_7 AntiSigma factor K07167 - - 0.00000000000000000000000000000000000000000000000000000000000002146 231.0
HKD2_k127_8139692_8 anaphase-promoting complex-dependent catabolic process - - - 0.00000000000000000000000000000000000000000000000000000001057 201.0
HKD2_k127_8139692_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000003985 200.0
HKD2_k127_8148324_0 Aminotransferase class-III K00822 - 2.6.1.18 2.026e-194 625.0
HKD2_k127_8148324_1 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 571.0
HKD2_k127_8148324_10 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000008498 99.0
HKD2_k127_8148324_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 567.0
HKD2_k127_8148324_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 569.0
HKD2_k127_8148324_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 548.0
HKD2_k127_8148324_5 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 484.0
HKD2_k127_8148324_6 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 302.0
HKD2_k127_8148324_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849,K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
HKD2_k127_8148324_8 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000007139 181.0
HKD2_k127_8148324_9 Domain of unknown function (DUF1906) - - - 0.0000000000000000000000000000000000000001154 153.0
HKD2_k127_8341372_0 protein histidine kinase activity K03407,K12257 - 2.7.13.3 0.0 2077.0
HKD2_k127_8341372_1 COG NOG06097 non supervised orthologous group - - - 0.0 1320.0
HKD2_k127_8341372_10 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 351.0
HKD2_k127_8341372_11 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 338.0
HKD2_k127_8341372_12 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 326.0
HKD2_k127_8341372_13 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 298.0
HKD2_k127_8341372_14 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002131 271.0
HKD2_k127_8341372_15 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
HKD2_k127_8341372_16 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000003685 196.0
HKD2_k127_8341372_17 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000002989 193.0
HKD2_k127_8341372_18 - - - - 0.000000000000000000000000000000000000000000000005613 178.0
HKD2_k127_8341372_19 Cupin domain - - - 0.0000000000000000000000000000000000000000000001604 171.0
HKD2_k127_8341372_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1272.0
HKD2_k127_8341372_20 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000003416 166.0
HKD2_k127_8341372_21 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000009012 149.0
HKD2_k127_8341372_22 redox protein regulator of disulfide bond formation K04063 - - 0.00000000000000000000000000000000001862 140.0
HKD2_k127_8341372_23 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000453 124.0
HKD2_k127_8341372_25 transport - - - 0.000000000001297 78.0
HKD2_k127_8341372_26 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia - - - 0.00000000003479 70.0
HKD2_k127_8341372_3 RecQ zinc-binding K03654 - 3.6.4.12 2.563e-238 744.0
HKD2_k127_8341372_4 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 471.0
HKD2_k127_8341372_5 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 432.0
HKD2_k127_8341372_6 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 424.0
HKD2_k127_8341372_7 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 426.0
HKD2_k127_8341372_8 Putative RNA methylase family UPF0020 K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 384.0
HKD2_k127_8341372_9 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 355.0
HKD2_k127_8482399_0 efflux transmembrane transporter activity - - - 2.252e-220 713.0
HKD2_k127_8482399_1 chlorophyll binding K02557,K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 352.0
HKD2_k127_8482399_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000001582 229.0
HKD2_k127_8482399_3 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000001509 216.0
HKD2_k127_8482399_5 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000009207 171.0
HKD2_k127_8482399_6 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000003355 126.0
HKD2_k127_8482399_7 Protein conserved in bacteria - - - 0.00000000000000000001153 99.0
HKD2_k127_8482399_8 YjbR - - - 0.000000000000004369 81.0
HKD2_k127_8482399_9 Serine aminopeptidase, S33 - - - 0.0005704 48.0
HKD2_k127_8590309_0 lysine biosynthetic process via aminoadipic acid - - - 8.028e-287 904.0
HKD2_k127_8590309_1 efflux transmembrane transporter activity - - - 4.178e-237 762.0
HKD2_k127_8590309_10 CHAT domain - - - 0.0000000000000000000000000000005604 143.0
HKD2_k127_8590309_11 Domain of unknown function (DUF4386) - - - 0.000000000000009763 85.0
HKD2_k127_8590309_2 PFAM major facilitator superfamily MFS_1 K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 512.0
HKD2_k127_8590309_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 431.0
HKD2_k127_8590309_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 348.0
HKD2_k127_8590309_5 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 324.0
HKD2_k127_8590309_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005697 258.0
HKD2_k127_8590309_7 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001704 247.0
HKD2_k127_8590309_8 sigma factor activity K02405 - - 0.0000000000000000000000000000000000004146 151.0
HKD2_k127_8590309_9 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000004049 134.0
HKD2_k127_8779669_0 Elongation factor G C-terminus K06207 - - 2.23e-315 977.0
HKD2_k127_8779669_1 LVIVD repeat - - - 4.144e-285 889.0
HKD2_k127_8779669_2 ABC transporter transmembrane region K11085 - - 2.398e-202 647.0
HKD2_k127_8779669_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 367.0
HKD2_k127_8779669_4 Domain of unknown function (DUF4142) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
HKD2_k127_8779669_6 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000001626 133.0
HKD2_k127_8779669_8 - - - - 0.0000000001822 73.0
HKD2_k127_8841154_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1212.0
HKD2_k127_8841154_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 5.222e-311 972.0
HKD2_k127_8841154_10 FixH - - - 0.00000000000000000000000000002149 136.0
HKD2_k127_8841154_11 SMART cyclic nucleotide-binding K10914 - - 0.000000000000000000000000005334 121.0
HKD2_k127_8841154_12 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0000000000000000000000002155 111.0
HKD2_k127_8841154_13 membrane transporter protein K07090 - - 0.00000000000000000000000105 114.0
HKD2_k127_8841154_14 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000000004586 69.0
HKD2_k127_8841154_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 579.0
HKD2_k127_8841154_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 470.0
HKD2_k127_8841154_4 metallopeptidase activity K01993,K13408,K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 469.0
HKD2_k127_8841154_5 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000007888 235.0
HKD2_k127_8841154_6 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000004924 204.0
HKD2_k127_8841154_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000008759 201.0
HKD2_k127_8841154_8 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000002084 212.0
HKD2_k127_8841154_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000002767 194.0
HKD2_k127_8915074_0 secondary active sulfate transmembrane transporter activity - - - 1.257e-311 974.0
HKD2_k127_8915074_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 463.0
HKD2_k127_8915074_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 314.0
HKD2_k127_8915074_3 CoA binding domain - - - 0.00000000000000000000000000000000004762 138.0
HKD2_k127_8948377_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 531.0
HKD2_k127_8948377_1 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 426.0
HKD2_k127_8948377_10 - - - - 0.00000000000000000000000000000272 129.0
HKD2_k127_8948377_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 368.0
HKD2_k127_8948377_3 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
HKD2_k127_8948377_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 312.0
HKD2_k127_8948377_5 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002121 296.0
HKD2_k127_8948377_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005448 251.0
HKD2_k127_8948377_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001348 260.0
HKD2_k127_8948377_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000009682 234.0
HKD2_k127_8948377_9 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000000003062 213.0
HKD2_k127_8965860_0 phospholipase C - - - 0.0 1133.0
HKD2_k127_8965860_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 545.0
HKD2_k127_8985403_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 612.0
HKD2_k127_8985403_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 433.0
HKD2_k127_8985403_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 296.0
HKD2_k127_8985403_3 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
HKD2_k127_8985403_4 ECF sigma factor - - - 0.0000000000000000000000000000000000001064 149.0
HKD2_k127_8985403_5 Subtilase family - - - 0.000000000000000000000000000000006656 140.0
HKD2_k127_8985403_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000006787 115.0
HKD2_k127_8985403_7 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000003226 105.0
HKD2_k127_8985403_8 Metal-sensitive transcriptional repressor - - - 0.000003978 51.0
HKD2_k127_8995171_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1373.0
HKD2_k127_8995171_1 Atp-dependent helicase - - - 0.0 1213.0
HKD2_k127_8995171_10 - - - - 0.0000000000000000000000000000000001543 149.0
HKD2_k127_8995171_11 Universal stress protein family - - - 0.000000000000000000000000000000002225 140.0
HKD2_k127_8995171_12 acetyltransferase - - - 0.000000000000000000000000000001124 123.0
HKD2_k127_8995171_13 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000000000118 120.0
HKD2_k127_8995171_14 permease - - - 0.000000000000000000000000003848 124.0
HKD2_k127_8995171_15 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K04108 - 1.3.7.9 0.00000000000000000000000006413 110.0
HKD2_k127_8995171_16 - - - - 0.00000000000000000004539 94.0
HKD2_k127_8995171_17 Universal stress protein family - - - 0.00000000000000000006178 102.0
HKD2_k127_8995171_18 Tfp pilus assembly protein FimT - - - 0.000000000000008309 80.0
HKD2_k127_8995171_19 - - - - 0.0000000000104 74.0
HKD2_k127_8995171_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 1.351e-197 635.0
HKD2_k127_8995171_20 Rdx family K07401 - - 0.0000009819 52.0
HKD2_k127_8995171_21 - - - - 0.00002606 52.0
HKD2_k127_8995171_3 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 587.0
HKD2_k127_8995171_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 574.0
HKD2_k127_8995171_5 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 508.0
HKD2_k127_8995171_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 349.0
HKD2_k127_8995171_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 325.0
HKD2_k127_8995171_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000004324 179.0
HKD2_k127_8995171_9 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000003716 152.0
HKD2_k127_8998039_0 Peptidase M14, carboxypeptidase A - - - 0.0 1218.0
HKD2_k127_8998039_1 cellulose binding - - - 3.701e-237 748.0
HKD2_k127_8998039_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000000003675 228.0
HKD2_k127_8998039_3 GrpB protein - - - 0.00000000000000000000000000000000003095 141.0
HKD2_k127_8998039_4 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000004504 96.0
HKD2_k127_8998039_5 efflux transmembrane transporter activity - - - 0.00000003742 61.0
HKD2_k127_9001810_0 esterase - - - 2.86e-282 875.0
HKD2_k127_9001810_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 630.0
HKD2_k127_9001810_10 cysteine-type peptidase activity K19224,K21471 - - 0.00000000000000000000000000000000000000004941 159.0
HKD2_k127_9001810_11 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.0000000333 59.0
HKD2_k127_9001810_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 567.0
HKD2_k127_9001810_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 578.0
HKD2_k127_9001810_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 543.0
HKD2_k127_9001810_5 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 465.0
HKD2_k127_9001810_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 429.0
HKD2_k127_9001810_7 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 352.0
HKD2_k127_9001810_8 Flavin-binding monooxygenase-like K07222,K18277 - 1.14.13.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 353.0
HKD2_k127_9001810_9 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000004903 233.0
HKD2_k127_9008396_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0 1197.0
HKD2_k127_9008396_1 Glycogen debranching enzyme - - - 1.654e-272 857.0
HKD2_k127_9008396_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 494.0
HKD2_k127_9008396_11 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 447.0
HKD2_k127_9008396_12 Copper amine oxidase, N2 domain K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 411.0
HKD2_k127_9008396_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 374.0
HKD2_k127_9008396_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 306.0
HKD2_k127_9008396_15 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001331 303.0
HKD2_k127_9008396_16 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007508 280.0
HKD2_k127_9008396_17 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001438 276.0
HKD2_k127_9008396_18 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HKD2_k127_9008396_19 NADPH-dependent FMN reductase K19784 - - 0.0000000000000000000000000000000000000000000000000000000005803 216.0
HKD2_k127_9008396_2 secondary active sulfate transmembrane transporter activity - - - 6.785e-270 852.0
HKD2_k127_9008396_20 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000001026 209.0
HKD2_k127_9008396_21 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000001595 202.0
HKD2_k127_9008396_23 - - - - 0.0000000000000000000000000000000000000843 151.0
HKD2_k127_9008396_24 Penicillinase repressor - - - 0.000000000000000000000000000000000005617 141.0
HKD2_k127_9008396_25 - - - - 0.00000000000000000000000000000004153 144.0
HKD2_k127_9008396_26 - - - - 0.00000000000000000000000000003646 128.0
HKD2_k127_9008396_27 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000769 126.0
HKD2_k127_9008396_3 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.647e-241 762.0
HKD2_k127_9008396_4 MacB-like periplasmic core domain - - - 1.017e-212 687.0
HKD2_k127_9008396_5 Rieske-like [2Fe-2S] domain - - - 2.092e-202 642.0
HKD2_k127_9008396_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 584.0
HKD2_k127_9008396_7 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 589.0
HKD2_k127_9008396_8 NAD(P) transhydrogenase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 535.0
HKD2_k127_9008396_9 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 493.0
HKD2_k127_9031779_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 400.0
HKD2_k127_9031779_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 260.0
HKD2_k127_9031779_2 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000009373 263.0
HKD2_k127_9031779_3 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006352 243.0
HKD2_k127_9031779_4 - - - - 0.000000000000000000000000000000000000000002671 161.0
HKD2_k127_9032782_0 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 542.0
HKD2_k127_9032782_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 483.0
HKD2_k127_9032782_10 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000008263 161.0
HKD2_k127_9032782_11 Protein of unknown function (DUF2878) - - - 0.00000000000000000000000000000000009356 147.0
HKD2_k127_9032782_12 - - - - 0.000000000000000000000000000000003709 133.0
HKD2_k127_9032782_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 450.0
HKD2_k127_9032782_3 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 407.0
HKD2_k127_9032782_4 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000001464 236.0
HKD2_k127_9032782_5 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000004021 241.0
HKD2_k127_9032782_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
HKD2_k127_9032782_7 AntiSigma factor K07167 - - 0.000000000000000000000000000000000000000000000000000000000000000213 229.0
HKD2_k127_9032782_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000005039 195.0
HKD2_k127_9032782_9 COG2771 DNA-binding HTH domain-containing proteins - - - 0.000000000000000000000000000000000000000001014 171.0
HKD2_k127_9034420_0 ASPIC UnbV domain protein - - - 0.0 1131.0
HKD2_k127_9034420_1 TonB-dependent receptor - - - 1.292e-256 827.0
HKD2_k127_9034420_2 CarboxypepD_reg-like domain - - - 2.858e-220 705.0
HKD2_k127_9034420_3 phosphorelay signal transduction system K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 570.0
HKD2_k127_9034420_4 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 511.0
HKD2_k127_9034420_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 312.0
HKD2_k127_9034420_6 transport - - - 0.000000000000000000000000000000000000000000000000000002535 200.0
HKD2_k127_9034420_7 TonB-linked outer membrane protein, SusC RagA family - - - 0.00026 51.0
HKD2_k127_9052478_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 8.431e-196 616.0
HKD2_k127_9052478_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 565.0
HKD2_k127_9052478_2 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 532.0
HKD2_k127_9052478_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 511.0
HKD2_k127_9052478_4 Competence-damaged protein K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 484.0
HKD2_k127_9052478_5 tryptophan 2,3-dioxygenase activity K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 356.0
HKD2_k127_9052478_6 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 326.0
HKD2_k127_9052478_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005955 254.0
HKD2_k127_9052478_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000001184 205.0
HKD2_k127_9052478_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000001985 154.0
HKD2_k127_9072740_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 500.0
HKD2_k127_9072740_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 365.0
HKD2_k127_9072740_2 AhpC/TSA family K02199 - - 0.00000000000000000000000000000005586 141.0
HKD2_k127_9072740_3 subunit of a heme lyase K02200 - - 0.0000000000000000000000002933 116.0
HKD2_k127_9072740_4 PFAM OsmC family protein - - - 0.000000000000000000001718 101.0
HKD2_k127_9104831_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 595.0
HKD2_k127_9104831_1 3-carboxy-cis,cis-muconate cycloisomerase K01857 - 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 542.0
HKD2_k127_9104831_2 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005782 284.0
HKD2_k127_9105861_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.284e-320 992.0
HKD2_k127_9105861_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.563e-259 809.0
HKD2_k127_9105861_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 447.0
HKD2_k127_9105861_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 392.0
HKD2_k127_9105861_4 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 341.0
HKD2_k127_9105861_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 352.0
HKD2_k127_9105861_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 327.0
HKD2_k127_9105861_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000016 74.0
HKD2_k127_9109275_0 Domain of unknown function (DUF5118) - - - 0.0 1185.0
HKD2_k127_9109275_1 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 452.0
HKD2_k127_9109275_10 SnoaL-like polyketide cyclase - - - 0.0000000000000000001447 95.0
HKD2_k127_9109275_11 Aminotransferase class I and II K00639 - 2.3.1.29 0.00000000007693 63.0
HKD2_k127_9109275_12 VanZ like family - - - 0.0003019 53.0
HKD2_k127_9109275_13 PFAM VanZ family protein - - - 0.0009203 51.0
HKD2_k127_9109275_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 346.0
HKD2_k127_9109275_3 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 286.0
HKD2_k127_9109275_4 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000258 252.0
HKD2_k127_9109275_5 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000005897 217.0
HKD2_k127_9109275_6 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000003581 175.0
HKD2_k127_9109275_7 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000005142 147.0
HKD2_k127_9109275_8 - - - - 0.00000000000000000000000000000001067 138.0
HKD2_k127_9109275_9 transport - - - 0.000000000000000000000000002003 128.0
HKD2_k127_9123647_0 cellulose binding - - - 2.17e-312 993.0
HKD2_k127_9123647_1 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009699 255.0
HKD2_k127_9123647_2 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000001187 130.0
HKD2_k127_9123647_3 MacB-like periplasmic core domain - - - 0.00000000000000000000000000002204 128.0
HKD2_k127_9123647_4 Cysteine dioxygenase type I - - - 0.000001328 51.0
HKD2_k127_9123647_5 Beta-lactamase - - - 0.00009502 54.0
HKD2_k127_9123647_6 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0001056 49.0
HKD2_k127_9126763_0 FAD binding domain - - - 2.917e-226 731.0
HKD2_k127_9126763_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 1.223e-217 685.0
HKD2_k127_9126763_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000001771 167.0
HKD2_k127_9126763_12 Glycosyltransferase WbsX - - - 0.00000000000000000000001184 102.0
HKD2_k127_9126763_14 Methionine biosynthesis protein MetW - - - 0.00000000005981 72.0
HKD2_k127_9126763_15 - - - - 0.0000002656 63.0
HKD2_k127_9126763_16 long-chain-acyl-CoA dehydrogenase activity K09479 GO:0000038,GO:0000062,GO:0000166,GO:0001659,GO:0003674,GO:0003824,GO:0003995,GO:0004466,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010565,GO:0015980,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0017099,GO:0019216,GO:0019217,GO:0019218,GO:0019222,GO:0019395,GO:0019752,GO:0019866,GO:0023052,GO:0030154,GO:0030258,GO:0030554,GO:0030855,GO:0030968,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033554,GO:0034440,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036094,GO:0036498,GO:0042221,GO:0042304,GO:0042592,GO:0042645,GO:0042760,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0046395,GO:0046890,GO:0048037,GO:0048519,GO:0048523,GO:0048856,GO:0048869,GO:0048871,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051055,GO:0051716,GO:0055114,GO:0060429,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:0072329,GO:0080090,GO:0090181,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.9 0.0000004075 55.0
HKD2_k127_9126763_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 482.0
HKD2_k127_9126763_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 422.0
HKD2_k127_9126763_4 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 424.0
HKD2_k127_9126763_5 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 382.0
HKD2_k127_9126763_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 339.0
HKD2_k127_9126763_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000007318 261.0
HKD2_k127_9126763_8 macromolecule localization K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000001163 236.0
HKD2_k127_9126763_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000004144 222.0
HKD2_k127_9137053_0 MacB-like periplasmic core domain - - - 0.0 1034.0
HKD2_k127_9137053_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 346.0
HKD2_k127_9137053_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001423 237.0
HKD2_k127_9146207_0 Peptidase family M28 - - - 2.09e-251 787.0
HKD2_k127_9146207_1 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 379.0
HKD2_k127_9157399_0 Erythromycin esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 477.0
HKD2_k127_9157399_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 316.0
HKD2_k127_9157399_10 ErfK ybiS ycfS ynhG family protein K19234 - - 0.0000000000000000000001426 109.0
HKD2_k127_9157399_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000009916 96.0
HKD2_k127_9157399_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
HKD2_k127_9157399_3 Helix-hairpin-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
HKD2_k127_9157399_4 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
HKD2_k127_9157399_5 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000001264 254.0
HKD2_k127_9157399_6 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003962 244.0
HKD2_k127_9157399_7 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000001664 163.0
HKD2_k127_9157399_8 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02003,K05685 - - 0.0000000000000000000000000000000002494 145.0
HKD2_k127_9157399_9 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000006976 131.0
HKD2_k127_9162949_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 600.0
HKD2_k127_9162949_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
HKD2_k127_9162949_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000001239 106.0
HKD2_k127_9162949_3 NapC/NirT cytochrome c family, N-terminal region K03532 - - 0.00006702 52.0
HKD2_k127_9200797_0 Sortilin, neurotensin receptor 3, - - - 3.266e-249 784.0
HKD2_k127_9200797_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 288.0
HKD2_k127_9200797_2 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003331 263.0
HKD2_k127_9200797_3 YCII-related domain - - - 0.0000000000000000000000000002209 121.0
HKD2_k127_9200797_4 - - - - 0.00000000002012 74.0
HKD2_k127_9248294_0 protein conserved in bacteria - - - 2.744e-254 802.0
HKD2_k127_9248294_1 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003029 279.0
HKD2_k127_9248294_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000007843 229.0
HKD2_k127_9248294_3 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000002116 214.0
HKD2_k127_9248294_4 Protein of unknown function (DUF4199) - - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
HKD2_k127_9248294_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000002423 194.0
HKD2_k127_9248294_6 - - - - 0.000000000000000000000000000001313 124.0
HKD2_k127_9248294_7 acetyltransferase - - - 0.0000000000000000001949 93.0
HKD2_k127_9248294_8 GNAT acetyltransferase - - - 0.0000003013 54.0
HKD2_k127_9248294_9 M61 glycyl aminopeptidase - - - 0.000488 48.0
HKD2_k127_9261886_0 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 478.0
HKD2_k127_9261886_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 398.0
HKD2_k127_9261886_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 424.0
HKD2_k127_9261886_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 348.0
HKD2_k127_9261886_4 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000001322 134.0
HKD2_k127_9261886_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000001299 126.0
HKD2_k127_9261886_6 - - - - 0.0000000000000000000000000001702 129.0
HKD2_k127_9261886_7 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000009612 115.0
HKD2_k127_9261886_8 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000004384 100.0
HKD2_k127_9284684_0 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 589.0
HKD2_k127_9284684_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001471 263.0
HKD2_k127_9284684_2 cellulase activity - - - 0.000000000001893 80.0
HKD2_k127_9284684_3 Ricin-type beta-trefoil - - - 0.0000000006569 71.0
HKD2_k127_9284684_4 Ricin-type beta-trefoil - - - 0.00000001459 67.0
HKD2_k127_9287712_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1095.0
HKD2_k127_9287712_1 Thiolase, C-terminal domain K02615 - 2.3.1.174,2.3.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 603.0
HKD2_k127_9287712_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 464.0
HKD2_k127_9287712_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
HKD2_k127_9287712_4 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 308.0
HKD2_k127_9287712_5 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
HKD2_k127_9287712_6 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000005811 174.0
HKD2_k127_9287712_7 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000001896 162.0
HKD2_k127_9387643_0 glucan 1,4-alpha-glucosidase activity - - - 1.185e-250 785.0
HKD2_k127_9387643_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 473.0
HKD2_k127_9387643_3 - - - - 0.000000000000000000000000000000000392 152.0
HKD2_k127_9387643_4 transport - - - 0.000000000000000001274 95.0
HKD2_k127_9387643_5 - - - - 0.00000000001213 71.0
HKD2_k127_9495113_0 Penicillin amidase - - - 0.0 1044.0
HKD2_k127_9495113_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 3.447e-207 667.0
HKD2_k127_9495113_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 355.0
HKD2_k127_9495113_11 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009226 239.0
HKD2_k127_9495113_12 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000003929 258.0
HKD2_k127_9495113_13 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
HKD2_k127_9495113_14 - - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD2_k127_9495113_15 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.000000000000000000000000000000000000000000000000000000002936 204.0
HKD2_k127_9495113_16 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000216 181.0
HKD2_k127_9495113_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000004185 191.0
HKD2_k127_9495113_18 - - - - 0.0000000000000000000000000000000000000000000001486 179.0
HKD2_k127_9495113_19 - - - - 0.00000000000000000000000000000000000001202 148.0
HKD2_k127_9495113_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 622.0
HKD2_k127_9495113_20 DsrC like protein K11179 - - 0.0000000000000000000000000000000002241 134.0
HKD2_k127_9495113_21 Histidine kinase - - - 0.0000000000000000000000000001144 133.0
HKD2_k127_9495113_22 - - - - 0.0000000000000000000000008586 111.0
HKD2_k127_9495113_23 transport - - - 0.00000000000000001251 97.0
HKD2_k127_9495113_24 Protein of Unknown function (DUF2784) - - - 0.000000000008448 66.0
HKD2_k127_9495113_27 Bacterial Ig-like domain 2 - - - 0.000009134 59.0
HKD2_k127_9495113_28 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00003055 53.0
HKD2_k127_9495113_3 pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 534.0
HKD2_k127_9495113_4 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 525.0
HKD2_k127_9495113_5 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 503.0
HKD2_k127_9495113_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 460.0
HKD2_k127_9495113_7 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 409.0
HKD2_k127_9495113_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HKD2_k127_9495113_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 411.0
HKD2_k127_9553500_0 Prolyl oligopeptidase family - - - 2.784e-288 913.0
HKD2_k127_9553500_1 ABC1 family - - - 1.502e-282 878.0
HKD2_k127_9553500_10 HAMP domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 450.0
HKD2_k127_9553500_11 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 417.0
HKD2_k127_9553500_12 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
HKD2_k127_9553500_13 Bacterial extracellular solute-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 370.0
HKD2_k127_9553500_14 Bacterial extracellular solute-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 369.0
HKD2_k127_9553500_15 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
HKD2_k127_9553500_16 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 338.0
HKD2_k127_9553500_17 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 333.0
HKD2_k127_9553500_18 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 331.0
HKD2_k127_9553500_19 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
HKD2_k127_9553500_2 Aldehyde dehydrogenase family K22187 - - 7.305e-271 852.0
HKD2_k127_9553500_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 304.0
HKD2_k127_9553500_21 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 304.0
HKD2_k127_9553500_22 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 293.0
HKD2_k127_9553500_23 negative regulation of phosphate transmembrane transport K02039 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004726 258.0
HKD2_k127_9553500_24 Putative ABC exporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005063 274.0
HKD2_k127_9553500_25 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000272 199.0
HKD2_k127_9553500_26 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HKD2_k127_9553500_27 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001197 198.0
HKD2_k127_9553500_28 - - - - 0.0000000000000000000000000000000000000000002789 165.0
HKD2_k127_9553500_29 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000002295 162.0
HKD2_k127_9553500_3 Bacterial regulatory protein, Fis family - - - 4.702e-220 694.0
HKD2_k127_9553500_30 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000001347 149.0
HKD2_k127_9553500_31 Intracellular proteinase inhibitor - - - 0.0000000000000000000000000000000001061 140.0
HKD2_k127_9553500_32 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000002963 123.0
HKD2_k127_9553500_33 - - - - 0.00000000000000000000000000009115 134.0
HKD2_k127_9553500_34 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000955 96.0
HKD2_k127_9553500_35 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000009825 78.0
HKD2_k127_9553500_36 Selenoprotein, putative - - - 0.0000000002351 61.0
HKD2_k127_9553500_37 - - - - 0.000000001192 67.0
HKD2_k127_9553500_38 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00001904 58.0
HKD2_k127_9553500_4 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 572.0
HKD2_k127_9553500_5 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 504.0
HKD2_k127_9553500_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 498.0
HKD2_k127_9553500_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 490.0
HKD2_k127_9553500_8 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 487.0
HKD2_k127_9553500_9 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 462.0
HKD2_k127_9567438_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1485.0
HKD2_k127_9567438_1 His Kinase A (phosphoacceptor) domain - - - 1.265e-309 987.0
HKD2_k127_9567438_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 447.0
HKD2_k127_9567438_11 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 433.0
HKD2_k127_9567438_12 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 437.0
HKD2_k127_9567438_13 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 441.0
HKD2_k127_9567438_14 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 421.0
HKD2_k127_9567438_15 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
HKD2_k127_9567438_16 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 344.0
HKD2_k127_9567438_17 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
HKD2_k127_9567438_18 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 325.0
HKD2_k127_9567438_19 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 320.0
HKD2_k127_9567438_2 serine-type peptidase activity - - - 1.013e-283 897.0
HKD2_k127_9567438_20 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 301.0
HKD2_k127_9567438_21 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001337 278.0
HKD2_k127_9567438_22 Cytochrome C oxidase, cbb3-type, subunit III K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000034 268.0
HKD2_k127_9567438_23 Uncharacterized protein conserved in bacteria (DUF2225) K09766 - - 0.000000000000000000000000000000000000000000000000000000000000000000000759 253.0
HKD2_k127_9567438_24 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000004607 252.0
HKD2_k127_9567438_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000002258 228.0
HKD2_k127_9567438_26 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000009845 235.0
HKD2_k127_9567438_27 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000007535 216.0
HKD2_k127_9567438_28 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
HKD2_k127_9567438_29 cytochrome c oxidase (Subunit II) - - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
HKD2_k127_9567438_3 ABC transporter transmembrane region K18890 - - 1.16e-238 752.0
HKD2_k127_9567438_30 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000000001567 194.0
HKD2_k127_9567438_31 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000001624 189.0
HKD2_k127_9567438_32 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000001014 186.0
HKD2_k127_9567438_33 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000001556 185.0
HKD2_k127_9567438_34 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000007815 178.0
HKD2_k127_9567438_35 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000001735 176.0
HKD2_k127_9567438_36 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000002667 156.0
HKD2_k127_9567438_37 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000006069 152.0
HKD2_k127_9567438_38 - - - - 0.00000000000000000000000000000000000001432 152.0
HKD2_k127_9567438_39 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000002261 144.0
HKD2_k127_9567438_4 PFAM Protein kinase domain - - - 1.267e-218 713.0
HKD2_k127_9567438_40 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000000000199 146.0
HKD2_k127_9567438_41 Protein conserved in bacteria - - - 0.0000000000000000000000000000000001285 152.0
HKD2_k127_9567438_42 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000001979 133.0
HKD2_k127_9567438_43 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000003199 117.0
HKD2_k127_9567438_44 DNA-binding transcription factor activity - - - 0.000000000000000000000000004582 123.0
HKD2_k127_9567438_45 Transcriptional regulator - - - 0.000000000000000000000000005103 122.0
HKD2_k127_9567438_46 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000009432 119.0
HKD2_k127_9567438_47 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002641 103.0
HKD2_k127_9567438_48 Transglycosylase associated protein - - - 0.00000000000000000000003453 115.0
HKD2_k127_9567438_49 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000005859 101.0
HKD2_k127_9567438_5 Nitronate monooxygenase - - - 1.734e-204 655.0
HKD2_k127_9567438_50 PFAM Transglycosylase-associated protein - - - 0.000000000000000000007138 95.0
HKD2_k127_9567438_51 Universal stress protein - - - 0.0000000000000000002799 99.0
HKD2_k127_9567438_52 Iron-sulfur cluster assembly protein - - - 0.000000000000000002998 94.0
HKD2_k127_9567438_53 Cupin 2, conserved barrel domain protein - - - 0.00000000000000008424 86.0
HKD2_k127_9567438_54 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits - - - 0.000000000003105 78.0
HKD2_k127_9567438_55 - - - - 0.0000000000075 73.0
HKD2_k127_9567438_56 Domain of Unknown function (DUF542) K07322 - - 0.0000000002422 65.0
HKD2_k127_9567438_57 SCO1/SenC K07152 - - 0.00000002007 68.0
HKD2_k127_9567438_6 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 613.0
HKD2_k127_9567438_7 domain, Protein K03980,K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 502.0
HKD2_k127_9567438_8 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 497.0
HKD2_k127_9567438_9 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 444.0
HKD2_k127_9578424_0 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 2.198e-315 997.0
HKD2_k127_9578424_1 TonB-dependent receptor K02014 - - 1.089e-288 914.0
HKD2_k127_9578424_10 SusD family K21572 - - 0.00000000000000000000000000000000000000000000000000000000000000000008008 252.0
HKD2_k127_9578424_11 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000001566 206.0
HKD2_k127_9578424_12 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000009209 179.0
HKD2_k127_9578424_13 - - - - 0.0000000000000000000000000000000000000195 153.0
HKD2_k127_9578424_14 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000004756 148.0
HKD2_k127_9578424_15 - - - - 0.0000000000007915 76.0
HKD2_k127_9578424_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 7.344e-268 832.0
HKD2_k127_9578424_3 TonB dependent receptor - - - 2.574e-236 766.0
HKD2_k127_9578424_4 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 584.0
HKD2_k127_9578424_5 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 505.0
HKD2_k127_9578424_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 449.0
HKD2_k127_9578424_7 Sodium:dicarboxylate symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 344.0
HKD2_k127_9578424_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 315.0
HKD2_k127_9578424_9 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001707 252.0
HKD2_k127_9623981_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 577.0
HKD2_k127_9623981_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 286.0
HKD2_k127_9623981_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000008015 209.0
HKD2_k127_9623981_3 - - - - 0.000000000000000006038 85.0
HKD2_k127_9623981_4 Cytochrome c K17760 - 1.1.9.1 0.000000008525 66.0
HKD2_k127_9623981_5 - - - - 0.00000003692 57.0
HKD2_k127_9653564_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2462.0
HKD2_k127_9653564_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2389.0
HKD2_k127_9653564_2 TonB-linked outer membrane protein, SusC RagA family - - - 7.048e-298 928.0
HKD2_k127_9653564_3 Starch-binding associating with outer membrane - - - 4.223e-221 709.0
HKD2_k127_9653564_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
HKD2_k127_9653564_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009789 255.0
HKD2_k127_9653564_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000003286 237.0
HKD2_k127_9653564_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
HKD2_k127_9653564_8 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000971 190.0
HKD2_k127_9680251_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 514.0
HKD2_k127_9680251_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 294.0
HKD2_k127_9680251_2 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000000007716 165.0
HKD2_k127_981778_0 ABC transporter transmembrane region K11085 - - 1.179e-295 925.0
HKD2_k127_981778_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 3.272e-253 800.0
HKD2_k127_981778_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 629.0
HKD2_k127_981778_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 611.0
HKD2_k127_981778_4 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 542.0
HKD2_k127_981778_5 response to abiotic stimulus K03086,K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 512.0
HKD2_k127_981778_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 372.0
HKD2_k127_981778_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 329.0
HKD2_k127_981778_8 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 241.0
HKD2_k127_981778_9 - - - - 0.00006773 51.0
HKD2_k127_9828536_0 TonB-dependent receptor K02014 - - 9.483e-206 666.0
HKD2_k127_9828536_1 Carboxypeptidase regulatory-like domain - - - 1.045e-202 674.0
HKD2_k127_9968333_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 565.0
HKD2_k127_9968333_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000004621 143.0
HKD2_k127_9968333_2 glyoxalase III activity K01259 - 3.4.11.5 0.0000000000000000000000000000000000007859 151.0
HKD2_k127_9968333_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002254 118.0
HKD2_k127_9968333_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000004156 94.0