logo

Overview

ID MAG01830
Name HKD2_bin.95
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus RBG-13-68-16
Species
Assembly information
Completeness (%) 90.48
Contamination (%) 2.24
GC content (%) 68.0
N50 (bp) 14,523
Genome size (bp) 2,845,821

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2426

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10114968_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000003692 190.0
HKD2_k127_10114968_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000008119 171.0
HKD2_k127_10114968_3 Protein of unknown function (DUF1232) - - - 0.000000000000000007766 90.0
HKD2_k127_102442_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 593.0
HKD2_k127_102442_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000003716 138.0
HKD2_k127_1047747_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 452.0
HKD2_k127_1047747_1 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 424.0
HKD2_k127_1047747_2 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
HKD2_k127_1047747_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000002511 162.0
HKD2_k127_1047747_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000001659 121.0
HKD2_k127_1047747_5 Domain of unknown function (DUF374) - - - 0.0000000000000000000000001605 114.0
HKD2_k127_1047747_6 Stage II sporulation protein - - - 0.00000000000000002192 94.0
HKD2_k127_1047747_7 - - - - 0.0000000000000006088 89.0
HKD2_k127_1047747_8 lysyltransferase activity K07027 - - 0.000000004088 63.0
HKD2_k127_110006_0 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 468.0
HKD2_k127_110006_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 380.0
HKD2_k127_110006_10 PFAM Tetratricopeptide repeat - - - 0.0000222 57.0
HKD2_k127_110006_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 301.0
HKD2_k127_110006_3 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 267.0
HKD2_k127_110006_4 mitochondrial electron transport, NADH to ubiquinone K10353 - 2.7.1.76 0.000000000000000000000000000000000000000000000000000000000000000000003532 255.0
HKD2_k127_110006_5 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001556 244.0
HKD2_k127_110006_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000004566 248.0
HKD2_k127_110006_7 ABC transporter, (ATP-binding protein) K01990 - - 0.00000000000000000000000000000000000000000000000000004498 192.0
HKD2_k127_110006_8 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000346 158.0
HKD2_k127_110006_9 DNA mismatch repair protein MutT - - - 0.0000000000000000000000000000001486 134.0
HKD2_k127_118114_0 Elongation factor G, domain IV K02355 - - 8.857e-200 647.0
HKD2_k127_118114_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 587.0
HKD2_k127_118114_11 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000002759 253.0
HKD2_k127_118114_12 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000128 238.0
HKD2_k127_118114_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
HKD2_k127_118114_14 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000009442 220.0
HKD2_k127_118114_15 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000003505 218.0
HKD2_k127_118114_16 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000002808 198.0
HKD2_k127_118114_17 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000004584 193.0
HKD2_k127_118114_18 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000001458 182.0
HKD2_k127_118114_19 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000003406 174.0
HKD2_k127_118114_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 590.0
HKD2_k127_118114_20 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000001643 168.0
HKD2_k127_118114_21 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000428 166.0
HKD2_k127_118114_22 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001647 151.0
HKD2_k127_118114_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000003941 154.0
HKD2_k127_118114_24 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001808 143.0
HKD2_k127_118114_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000003924 153.0
HKD2_k127_118114_26 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000006823 141.0
HKD2_k127_118114_27 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000003101 140.0
HKD2_k127_118114_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000003059 143.0
HKD2_k127_118114_29 Alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000005884 136.0
HKD2_k127_118114_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 592.0
HKD2_k127_118114_30 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000006267 139.0
HKD2_k127_118114_31 DinB superfamily - - - 0.0000000000000000000000000000006123 130.0
HKD2_k127_118114_32 CHASE K11444 - 2.7.7.65 0.000000000000000000000000000002988 139.0
HKD2_k127_118114_33 Cold shock protein K03704 - - 0.0000000000000000000000000002249 116.0
HKD2_k127_118114_34 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000001632 122.0
HKD2_k127_118114_35 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000003328 114.0
HKD2_k127_118114_36 Outer membrane lipoprotein - - - 0.000000000000000000000000335 120.0
HKD2_k127_118114_37 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000009584 108.0
HKD2_k127_118114_38 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000007536 109.0
HKD2_k127_118114_39 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000009754 100.0
HKD2_k127_118114_4 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 419.0
HKD2_k127_118114_40 Smr domain - - - 0.00000000000000000002426 104.0
HKD2_k127_118114_41 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001523 74.0
HKD2_k127_118114_42 Forkhead associated domain - - - 0.000000000008377 75.0
HKD2_k127_118114_43 - - - - 0.0000000004285 65.0
HKD2_k127_118114_44 TonB C terminal K03832 - - 0.000000085 63.0
HKD2_k127_118114_45 RDD family - - - 0.000004451 57.0
HKD2_k127_118114_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 354.0
HKD2_k127_118114_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 335.0
HKD2_k127_118114_7 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 305.0
HKD2_k127_118114_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 301.0
HKD2_k127_118114_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
HKD2_k127_1304721_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 3.054e-235 750.0
HKD2_k127_1308446_0 von Willebrand factor, type A K07114 - - 3.253e-265 843.0
HKD2_k127_1308446_1 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 603.0
HKD2_k127_1308446_10 - - - - 0.000000001316 71.0
HKD2_k127_1308446_2 5' nucleotidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 599.0
HKD2_k127_1308446_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 489.0
HKD2_k127_1308446_4 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 469.0
HKD2_k127_1308446_5 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000004276 160.0
HKD2_k127_1308446_6 Domain of Unknown Function with PDB structure (DUF3858) - - - 0.000000000000000000000000000037 136.0
HKD2_k127_1308446_7 PFAM membrane protein of K08972 - - 0.0000000000000000000000007386 108.0
HKD2_k127_1308446_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000005027 108.0
HKD2_k127_1308446_9 Aldehyde dehydrogenase family - - - 0.000000000000000000002078 95.0
HKD2_k127_1309696_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 293.0
HKD2_k127_1309696_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000004218 239.0
HKD2_k127_1309696_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000008755 199.0
HKD2_k127_1309696_3 - - - - 0.00000009118 64.0
HKD2_k127_1329840_0 PFAM Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 381.0
HKD2_k127_1329840_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 347.0
HKD2_k127_1329840_2 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 335.0
HKD2_k127_1329840_3 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001729 273.0
HKD2_k127_1329840_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000005372 144.0
HKD2_k127_1329840_5 - - - - 0.000000002033 66.0
HKD2_k127_1329840_6 Belongs to the UPF0761 family K07058 - - 0.000002368 58.0
HKD2_k127_1329840_7 Domain of unknown function (DUF4136) - - - 0.00001739 54.0
HKD2_k127_1329840_8 Calcineurin-like phosphoesterase - - - 0.0003775 52.0
HKD2_k127_1332379_0 AcrB/AcrD/AcrF family - - - 0.0 1234.0
HKD2_k127_1332379_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
HKD2_k127_1332379_2 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001698 249.0
HKD2_k127_1332379_3 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000002418 250.0
HKD2_k127_1332379_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000006254 198.0
HKD2_k127_1332379_5 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000001163 160.0
HKD2_k127_1332379_6 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000165 149.0
HKD2_k127_1332379_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000002899 61.0
HKD2_k127_1349944_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 286.0
HKD2_k127_1349944_1 PFAM peptidase - - - 0.0000000000000000000000000000000000001338 160.0
HKD2_k127_1349944_2 Thiamine-binding protein - - - 0.00000000000000000000000000000000008583 135.0
HKD2_k127_1349944_3 ABC transporter K02003 - - 0.00000000000000000000000000000000009088 135.0
HKD2_k127_1349944_4 - - - - 0.0000000000000000357 82.0
HKD2_k127_1349944_5 ACT domain K09707 - - 0.00000004942 60.0
HKD2_k127_1358258_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 598.0
HKD2_k127_1358258_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005441 254.0
HKD2_k127_1358258_2 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000004871 238.0
HKD2_k127_1358258_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.000000000000000000000000000000000000000000001273 169.0
HKD2_k127_1358258_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.00000000000000000000000000000000000002109 152.0
HKD2_k127_1358258_5 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000001047 122.0
HKD2_k127_1359991_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 537.0
HKD2_k127_1359991_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 489.0
HKD2_k127_1359991_3 Domain of unknown function (DUF4156) - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00004835 51.0
HKD2_k127_1361875_0 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000023 139.0
HKD2_k127_1361875_1 AsmA family K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000001877 122.0
HKD2_k127_1361875_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000000001776 111.0
HKD2_k127_1366212_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 339.0
HKD2_k127_1366212_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000009187 138.0
HKD2_k127_1366212_2 tryptophanase activity K01667 - 4.1.99.1 0.0000000000000000000000000002708 119.0
HKD2_k127_1366212_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002096 83.0
HKD2_k127_1417203_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 385.0
HKD2_k127_1417203_1 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 373.0
HKD2_k127_1417203_10 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000001525 66.0
HKD2_k127_1417203_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 351.0
HKD2_k127_1417203_3 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 307.0
HKD2_k127_1417203_4 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000005739 235.0
HKD2_k127_1417203_5 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000008845 195.0
HKD2_k127_1417203_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000002002 199.0
HKD2_k127_1417203_7 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002512 204.0
HKD2_k127_1417203_8 Putative regulatory protein - - - 0.0000000000000000000000007745 111.0
HKD2_k127_1417203_9 - - - - 0.0000000000000000005449 93.0
HKD2_k127_1491786_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 598.0
HKD2_k127_1491786_1 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 417.0
HKD2_k127_1491786_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000044 222.0
HKD2_k127_1491786_3 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000001724 198.0
HKD2_k127_1491786_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000546 157.0
HKD2_k127_1491786_5 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000000000001831 149.0
HKD2_k127_1496283_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003005 269.0
HKD2_k127_1508433_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
HKD2_k127_1508433_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 336.0
HKD2_k127_1508433_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000002006 117.0
HKD2_k127_1508433_11 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000002156 77.0
HKD2_k127_1508433_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
HKD2_k127_1508433_3 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 264.0
HKD2_k127_1508433_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
HKD2_k127_1508433_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000001003 239.0
HKD2_k127_1508433_6 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001004 217.0
HKD2_k127_1508433_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000791 196.0
HKD2_k127_1508433_8 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000002199 182.0
HKD2_k127_1508433_9 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000003229 127.0
HKD2_k127_1580558_0 tagaturonate epimerase - - - 3.145e-208 666.0
HKD2_k127_1580558_1 PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 607.0
HKD2_k127_1580558_2 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 583.0
HKD2_k127_1580558_3 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 496.0
HKD2_k127_1580558_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 348.0
HKD2_k127_1596909_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 453.0
HKD2_k127_1596909_1 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 439.0
HKD2_k127_1596909_2 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004891 278.0
HKD2_k127_1596909_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008756 248.0
HKD2_k127_1596909_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000001278 244.0
HKD2_k127_1596909_5 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000004845 207.0
HKD2_k127_1596909_6 PA domain K14647 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000001175 159.0
HKD2_k127_1596909_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000006275 128.0
HKD2_k127_1596909_8 - - - - 0.00001705 54.0
HKD2_k127_1632307_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 472.0
HKD2_k127_1632307_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 389.0
HKD2_k127_1632307_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 334.0
HKD2_k127_1632307_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 302.0
HKD2_k127_1632307_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HKD2_k127_1632307_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000005125 179.0
HKD2_k127_1632307_6 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.000000000000000000000000000000005943 139.0
HKD2_k127_1667436_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.946e-265 835.0
HKD2_k127_1667436_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 531.0
HKD2_k127_1667436_10 Universal stress protein - - - 0.000000000000000000000000000001512 132.0
HKD2_k127_1667436_11 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000004803 113.0
HKD2_k127_1667436_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 412.0
HKD2_k127_1667436_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 336.0
HKD2_k127_1667436_4 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
HKD2_k127_1667436_5 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000005019 226.0
HKD2_k127_1667436_6 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000002678 202.0
HKD2_k127_1667436_7 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.000000000000000000000000000000000000000000001261 181.0
HKD2_k127_1667436_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000002273 165.0
HKD2_k127_1667436_9 Protein tyrosine kinase - - - 0.0000000000000000000000000000000001584 143.0
HKD2_k127_16775_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 591.0
HKD2_k127_16775_1 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 435.0
HKD2_k127_16775_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
HKD2_k127_16775_3 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 336.0
HKD2_k127_16775_4 mandelate racemase muconate lactonizing K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 302.0
HKD2_k127_16775_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000005041 200.0
HKD2_k127_16775_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000005728 212.0
HKD2_k127_16775_7 GYD domain - - - 0.000000000000000000000000000002243 126.0
HKD2_k127_16775_8 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000004596 56.0
HKD2_k127_16775_9 Calcineurin-like phosphoesterase - - - 0.0000005391 61.0
HKD2_k127_1689518_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009016 282.0
HKD2_k127_1689518_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001089 269.0
HKD2_k127_1689518_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD2_k127_1689518_3 TonB-dependent receptor plug - - - 0.0000000000000000000000000000000000000000000000000000000000007873 216.0
HKD2_k127_1689518_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000003461 134.0
HKD2_k127_1689518_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000272 106.0
HKD2_k127_1689518_6 peptidase M36 - - - 0.000005587 58.0
HKD2_k127_1689518_7 FR47-like protein - - - 0.0001671 51.0
HKD2_k127_1690882_0 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 487.0
HKD2_k127_1690882_1 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 412.0
HKD2_k127_1690882_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 318.0
HKD2_k127_1690882_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD2_k127_1690882_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
HKD2_k127_1690882_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000008649 194.0
HKD2_k127_1690882_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000029 192.0
HKD2_k127_1690882_7 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000001634 176.0
HKD2_k127_1704036_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 310.0
HKD2_k127_1766080_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 329.0
HKD2_k127_1766080_1 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 303.0
HKD2_k127_1766080_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 291.0
HKD2_k127_1766080_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000263 223.0
HKD2_k127_1766080_4 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000001869 181.0
HKD2_k127_1789615_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 450.0
HKD2_k127_1789615_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
HKD2_k127_1789615_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000453 57.0
HKD2_k127_1789615_11 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0003834 51.0
HKD2_k127_1789615_2 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000005481 194.0
HKD2_k127_1789615_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000001381 165.0
HKD2_k127_1789615_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000006884 159.0
HKD2_k127_1789615_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000002356 127.0
HKD2_k127_1789615_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001728 106.0
HKD2_k127_1789615_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000006385 96.0
HKD2_k127_1789615_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000009491 95.0
HKD2_k127_1789615_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000006832 88.0
HKD2_k127_1799517_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.19e-277 876.0
HKD2_k127_1799517_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.306e-204 651.0
HKD2_k127_1799517_10 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000001886 75.0
HKD2_k127_1799517_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 472.0
HKD2_k127_1799517_3 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 452.0
HKD2_k127_1799517_4 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 305.0
HKD2_k127_1799517_5 Alpha beta - - - 0.00000000000000000000000000000000000000000000000000000006487 206.0
HKD2_k127_1799517_6 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000002464 165.0
HKD2_k127_1799517_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000388 153.0
HKD2_k127_1799517_8 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000005217 127.0
HKD2_k127_1799517_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000002544 96.0
HKD2_k127_180654_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 543.0
HKD2_k127_180654_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002801 225.0
HKD2_k127_180654_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001649 142.0
HKD2_k127_180654_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000004385 105.0
HKD2_k127_180654_4 ig-like, plexins, transcription factors - - - 0.00000000000000001923 95.0
HKD2_k127_180654_5 Tetratricopeptide repeat - - - 0.000000006027 68.0
HKD2_k127_180654_6 Roadblock/LC7 domain - - - 0.00000002186 62.0
HKD2_k127_18222_0 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000002579 138.0
HKD2_k127_18222_1 - - - - 0.00000000001078 73.0
HKD2_k127_1833932_0 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 3.654e-268 843.0
HKD2_k127_1833932_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 336.0
HKD2_k127_1833932_2 Calcineurin-like phosphoesterase K07098 - - 0.0001238 49.0
HKD2_k127_1979524_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003112 255.0
HKD2_k127_1979524_1 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000333 190.0
HKD2_k127_1979524_2 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000000000000000000000000000000000006517 156.0
HKD2_k127_2043146_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 312.0
HKD2_k127_2043146_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000009776 203.0
HKD2_k127_2043146_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000003424 179.0
HKD2_k127_2043146_3 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000001029 149.0
HKD2_k127_2043146_4 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.000000000000000000001763 108.0
HKD2_k127_2043146_5 antisigma factor binding - - - 0.00000000000000008439 85.0
HKD2_k127_2043146_6 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000002919 84.0
HKD2_k127_2094770_0 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000003979 179.0
HKD2_k127_2094770_1 PFAM Surface antigen - - - 0.000000001838 68.0
HKD2_k127_211061_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 340.0
HKD2_k127_211061_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000001169 201.0
HKD2_k127_211061_2 - - - - 0.000000000000000000000000000000000000001622 157.0
HKD2_k127_211061_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.000000000000004191 76.0
HKD2_k127_2184150_0 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.000000000000000001426 99.0
HKD2_k127_2184150_1 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.00000000000000001166 97.0
HKD2_k127_2184150_2 PFAM Glycosyl transferases group 1 - - - 0.000000000001903 76.0
HKD2_k127_226356_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.158e-198 625.0
HKD2_k127_226356_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000001114 121.0
HKD2_k127_2266321_0 PFAM Prolyl oligopeptidase family - - - 1.505e-230 730.0
HKD2_k127_2266321_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
HKD2_k127_2560739_1 gluconolactonase activity - - - 0.00000000000000000000000000000002305 139.0
HKD2_k127_2562957_0 hydrogenase large subunit K14126 - 1.8.98.5 5.237e-237 739.0
HKD2_k127_2562957_1 Heat shock 70 kDa protein K04043 - - 1.434e-225 715.0
HKD2_k127_2562957_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000006789 141.0
HKD2_k127_2562957_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000002259 134.0
HKD2_k127_2562957_12 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000005799 95.0
HKD2_k127_2562957_13 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000001839 106.0
HKD2_k127_2562957_14 Domain of unknown function (DUF2520) - - - 0.0000000000000001472 91.0
HKD2_k127_2562957_15 - - - - 0.0000003293 58.0
HKD2_k127_2562957_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 474.0
HKD2_k127_2562957_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 453.0
HKD2_k127_2562957_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
HKD2_k127_2562957_5 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001454 281.0
HKD2_k127_2562957_6 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006676 253.0
HKD2_k127_2562957_7 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000001265 245.0
HKD2_k127_2562957_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000001052 208.0
HKD2_k127_2562957_9 Hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000009788 160.0
HKD2_k127_2568014_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 1.114e-284 904.0
HKD2_k127_2568014_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 547.0
HKD2_k127_2568014_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
HKD2_k127_2568014_3 Acid phosphatase - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000002661 132.0
HKD2_k127_2568014_4 Iodothyronine deiodinase - - - 0.0000006041 61.0
HKD2_k127_2568014_5 Oar protein - - - 0.0000234 56.0
HKD2_k127_2570268_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.936e-231 731.0
HKD2_k127_2570268_1 Ami_2 - - - 0.00000000002971 74.0
HKD2_k127_2575045_0 Carbohydrate phosphorylase K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 1.105e-264 832.0
HKD2_k127_2575045_1 Phosphoglycerol transferase family protein, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 509.0
HKD2_k127_2575829_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1082.0
HKD2_k127_2575829_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 1.022e-265 841.0
HKD2_k127_2575829_2 Involved in the tonB-independent uptake of proteins - - - 2.424e-224 723.0
HKD2_k127_2575829_3 C4-dicarboxylate anaerobic carrier - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 406.0
HKD2_k127_2575829_4 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000008832 223.0
HKD2_k127_2575829_5 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000003992 76.0
HKD2_k127_257676_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 455.0
HKD2_k127_257676_1 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.0000000002508 64.0
HKD2_k127_2578481_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 561.0
HKD2_k127_2578481_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 536.0
HKD2_k127_2578481_2 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 407.0
HKD2_k127_2578481_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003022 267.0
HKD2_k127_2578481_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000009846 205.0
HKD2_k127_2578481_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000001588 190.0
HKD2_k127_2578481_6 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000004561 170.0
HKD2_k127_2586842_0 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 511.0
HKD2_k127_2586842_1 glycosyltransferase 36 associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 490.0
HKD2_k127_2588483_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.528e-249 783.0
HKD2_k127_2588483_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000001656 186.0
HKD2_k127_2588483_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000001476 168.0
HKD2_k127_2588483_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000009957 130.0
HKD2_k127_2588483_4 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000001457 111.0
HKD2_k127_2588483_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000002507 116.0
HKD2_k127_2588483_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000007621 99.0
HKD2_k127_2588483_7 GGDEF domain - - - 0.000000000001661 75.0
HKD2_k127_2589931_0 ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
HKD2_k127_2589931_1 SWI complex, BAF60b domains - - - 0.00000000000000000002488 91.0
HKD2_k127_2592343_0 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 465.0
HKD2_k127_2592343_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 400.0
HKD2_k127_2592343_10 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000001265 106.0
HKD2_k127_2592343_11 - - - - 0.0000000000000000000001663 100.0
HKD2_k127_2592343_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 335.0
HKD2_k127_2592343_3 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 296.0
HKD2_k127_2592343_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000672 278.0
HKD2_k127_2592343_5 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000644 239.0
HKD2_k127_2592343_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
HKD2_k127_2592343_7 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000007444 175.0
HKD2_k127_2592343_8 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000004976 171.0
HKD2_k127_2592343_9 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000002005 120.0
HKD2_k127_2596411_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 313.0
HKD2_k127_2596411_1 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000003424 196.0
HKD2_k127_2596411_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000002399 147.0
HKD2_k127_2615804_0 Belongs to the ClpA ClpB family K03696 - - 1.221e-265 844.0
HKD2_k127_2615804_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 535.0
HKD2_k127_2615804_10 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 309.0
HKD2_k127_2615804_11 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008527 271.0
HKD2_k127_2615804_12 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001548 280.0
HKD2_k127_2615804_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
HKD2_k127_2615804_14 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
HKD2_k127_2615804_15 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002269 229.0
HKD2_k127_2615804_16 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000005837 241.0
HKD2_k127_2615804_17 - - - - 0.0000000000000000000000000000000000000000000000000000000007248 228.0
HKD2_k127_2615804_18 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000001667 220.0
HKD2_k127_2615804_19 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000008684 211.0
HKD2_k127_2615804_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 524.0
HKD2_k127_2615804_20 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000744 173.0
HKD2_k127_2615804_21 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000001947 184.0
HKD2_k127_2615804_22 spore germination K03298 - - 0.00000000000000000000000000000000000000001018 164.0
HKD2_k127_2615804_23 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000006093 134.0
HKD2_k127_2615804_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000005874 117.0
HKD2_k127_2615804_25 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000004752 124.0
HKD2_k127_2615804_26 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000008082 106.0
HKD2_k127_2615804_27 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002446 87.0
HKD2_k127_2615804_28 ribonuclease BN K07058 - - 0.0000000000008337 81.0
HKD2_k127_2615804_29 snoRNA binding - - - 0.000002213 55.0
HKD2_k127_2615804_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 471.0
HKD2_k127_2615804_30 alkaline phosphatase - - - 0.0008175 45.0
HKD2_k127_2615804_4 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
HKD2_k127_2615804_5 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 429.0
HKD2_k127_2615804_6 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 411.0
HKD2_k127_2615804_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 374.0
HKD2_k127_2615804_8 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 395.0
HKD2_k127_2615804_9 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 349.0
HKD2_k127_2631488_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000003201 147.0
HKD2_k127_2631488_1 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000009153 118.0
HKD2_k127_2631488_2 - - - - 0.00000000000000000001735 101.0
HKD2_k127_2637192_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 536.0
HKD2_k127_2637192_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000004768 83.0
HKD2_k127_2637192_2 Subtilase family - - - 0.0000000052 65.0
HKD2_k127_2637192_3 Tetratricopeptide repeat - - - 0.0002743 54.0
HKD2_k127_2637192_4 transcriptional activator K03765 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0004914 50.0
HKD2_k127_2650601_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 542.0
HKD2_k127_2650601_1 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
HKD2_k127_2650601_2 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 456.0
HKD2_k127_2650601_3 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 396.0
HKD2_k127_2650601_4 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 350.0
HKD2_k127_2650601_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 336.0
HKD2_k127_2650601_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
HKD2_k127_2650601_7 PFAM Ferritin Dps family protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000243 181.0
HKD2_k127_2650601_8 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000007981 150.0
HKD2_k127_2650601_9 Transcription factor zinc-finger K09981 - - 0.00000000000000000000002957 106.0
HKD2_k127_2652922_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 307.0
HKD2_k127_2652922_1 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000003047 227.0
HKD2_k127_2652922_2 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000000000002228 205.0
HKD2_k127_2664431_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 579.0
HKD2_k127_2664431_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 533.0
HKD2_k127_2664431_10 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000001304 123.0
HKD2_k127_2664431_11 DoxX - - - 0.00000000000000000000000003252 113.0
HKD2_k127_2664431_12 PFAM Peptidase M23 - - - 0.0000000000000000008187 99.0
HKD2_k127_2664431_13 Rhodanese Homology Domain - - - 0.0000008957 58.0
HKD2_k127_2664431_15 Protease prsW family - - - 0.0006236 52.0
HKD2_k127_2664431_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 426.0
HKD2_k127_2664431_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 399.0
HKD2_k127_2664431_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 400.0
HKD2_k127_2664431_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000004127 234.0
HKD2_k127_2664431_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
HKD2_k127_2664431_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002284 164.0
HKD2_k127_2664431_8 ApaG domain K06195 - - 0.0000000000000000000000000000000000000338 166.0
HKD2_k127_2664431_9 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000007069 148.0
HKD2_k127_2664549_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 612.0
HKD2_k127_2664549_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 589.0
HKD2_k127_2664549_10 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002816 289.0
HKD2_k127_2664549_11 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
HKD2_k127_2664549_12 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003895 270.0
HKD2_k127_2664549_13 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HKD2_k127_2664549_14 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004544 242.0
HKD2_k127_2664549_15 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000001139 215.0
HKD2_k127_2664549_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000603 195.0
HKD2_k127_2664549_17 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K15876 - - 0.000000000000000000000000000000000000000000003853 169.0
HKD2_k127_2664549_18 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000006762 158.0
HKD2_k127_2664549_19 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000006948 161.0
HKD2_k127_2664549_2 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 521.0
HKD2_k127_2664549_20 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000001603 151.0
HKD2_k127_2664549_21 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000002413 159.0
HKD2_k127_2664549_22 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000001517 155.0
HKD2_k127_2664549_23 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000006962 150.0
HKD2_k127_2664549_24 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000001638 142.0
HKD2_k127_2664549_25 The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis K13830 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 1.1.1.25,2.5.1.19,2.7.1.71,4.2.1.10,4.2.3.4 0.0000000000000000000000000000000000244 153.0
HKD2_k127_2664549_26 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000155 134.0
HKD2_k127_2664549_27 cytochrome c - - - 0.000000000000000000000000000008555 126.0
HKD2_k127_2664549_28 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000581 121.0
HKD2_k127_2664549_29 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000002816 115.0
HKD2_k127_2664549_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 489.0
HKD2_k127_2664549_30 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000002303 119.0
HKD2_k127_2664549_31 Serine aminopeptidase, S33 - - - 0.000000000000000000004609 104.0
HKD2_k127_2664549_32 Protein of unknown function (DUF3341) - - - 0.00000000007262 69.0
HKD2_k127_2664549_33 DinB family - - - 0.0000000001614 70.0
HKD2_k127_2664549_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 488.0
HKD2_k127_2664549_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 430.0
HKD2_k127_2664549_6 Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 387.0
HKD2_k127_2664549_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 319.0
HKD2_k127_2664549_8 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 317.0
HKD2_k127_2664549_9 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 309.0
HKD2_k127_26672_0 WD40-like Beta Propeller Repeat - - - 0.0000000002603 73.0
HKD2_k127_2687631_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 522.0
HKD2_k127_2687631_1 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000002313 229.0
HKD2_k127_2687631_2 nickel cation binding K04651 - - 0.00000000000005516 83.0
HKD2_k127_2691414_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.661e-229 721.0
HKD2_k127_2691414_1 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 520.0
HKD2_k127_2691414_2 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
HKD2_k127_2691414_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000001333 218.0
HKD2_k127_2691414_4 protein conserved in bacteria - - - 0.0000000000000000000000000005433 117.0
HKD2_k127_2691414_5 spore coat K01790 - 5.1.3.13 0.00000000000000000000000002657 115.0
HKD2_k127_2691414_6 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000008277 61.0
HKD2_k127_2691414_7 Family with sequence similarity 174, member A - - - 0.0001208 53.0
HKD2_k127_2691610_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
HKD2_k127_2691610_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000004859 186.0
HKD2_k127_2691610_2 light absorption K06893 - - 0.000000000000000000000000000000002097 133.0
HKD2_k127_2691610_3 DinB superfamily - - - 0.000009353 48.0
HKD2_k127_2694493_0 Phosphotransferase enzyme family - - - 6.226e-281 898.0
HKD2_k127_2694493_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 631.0
HKD2_k127_2694493_10 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
HKD2_k127_2694493_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000005779 171.0
HKD2_k127_2694493_13 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000002958 89.0
HKD2_k127_2694493_14 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000001234 78.0
HKD2_k127_2694493_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 387.0
HKD2_k127_2694493_3 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
HKD2_k127_2694493_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 352.0
HKD2_k127_2694493_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 322.0
HKD2_k127_2694493_6 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 297.0
HKD2_k127_2694493_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000711 260.0
HKD2_k127_2694493_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
HKD2_k127_2705952_0 aconitate hydratase K01681 - 4.2.1.3 2.042e-317 990.0
HKD2_k127_2705952_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 441.0
HKD2_k127_2705952_10 Putative adhesin - - - 0.0000001398 63.0
HKD2_k127_2705952_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 299.0
HKD2_k127_2705952_3 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008031 263.0
HKD2_k127_2705952_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001659 225.0
HKD2_k127_2705952_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001366 183.0
HKD2_k127_2705952_6 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000000000001441 134.0
HKD2_k127_2705952_7 Domain of unknown function (DUF4340) - - - 0.0000000000000000001752 104.0
HKD2_k127_2705952_8 symporter activity K11928 - - 0.000000000000001103 79.0
HKD2_k127_2705952_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000009105 70.0
HKD2_k127_2706316_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009501 267.0
HKD2_k127_2706316_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000003068 198.0
HKD2_k127_2706316_2 aldo keto reductase family K07079 - - 0.000000000000000000000000000000135 140.0
HKD2_k127_2706316_3 - - - - 0.00000000000000000724 94.0
HKD2_k127_2706316_4 enterobactin catabolic process K07214 - - 0.000000002129 69.0
HKD2_k127_2706316_5 - - - - 0.0002681 51.0
HKD2_k127_2721847_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 421.0
HKD2_k127_2721847_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 371.0
HKD2_k127_2721847_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000003421 203.0
HKD2_k127_2747627_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 346.0
HKD2_k127_2747627_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 330.0
HKD2_k127_2753729_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1049.0
HKD2_k127_2753729_1 Oligopeptide transporter OPT - - - 5.33e-247 782.0
HKD2_k127_2753729_10 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 339.0
HKD2_k127_2753729_11 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 328.0
HKD2_k127_2753729_12 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 301.0
HKD2_k127_2753729_13 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006537 287.0
HKD2_k127_2753729_14 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000004391 215.0
HKD2_k127_2753729_15 ABC transporter, ATP-binding protein K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000008658 201.0
HKD2_k127_2753729_16 transmembrane transport - - - 0.00000000000000000000000000000000000000001344 164.0
HKD2_k127_2753729_17 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000002626 142.0
HKD2_k127_2753729_18 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000005128 139.0
HKD2_k127_2753729_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000002024 146.0
HKD2_k127_2753729_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 572.0
HKD2_k127_2753729_20 hydrolase (HAD superfamily) K07026 - 3.1.3.70 0.00000000000000000000000000000003018 137.0
HKD2_k127_2753729_21 histidine kinase A domain protein - - - 0.000000000000000000000000000001272 132.0
HKD2_k127_2753729_22 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000004357 121.0
HKD2_k127_2753729_23 Tetratricopeptide repeat K08309 - - 0.000000000000000000000007733 119.0
HKD2_k127_2753729_24 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001726 86.0
HKD2_k127_2753729_25 nuclear chromosome segregation - - - 0.0000000000002526 82.0
HKD2_k127_2753729_26 DivIVA domain K04074 - - 0.0000000003702 67.0
HKD2_k127_2753729_27 C4-type zinc ribbon domain K07164 - - 0.000000001543 68.0
HKD2_k127_2753729_28 ABC transporter K02013 - 3.6.3.34 0.0000003933 63.0
HKD2_k127_2753729_29 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00001745 55.0
HKD2_k127_2753729_3 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 512.0
HKD2_k127_2753729_4 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 516.0
HKD2_k127_2753729_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 503.0
HKD2_k127_2753729_6 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 491.0
HKD2_k127_2753729_7 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 394.0
HKD2_k127_2753729_8 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 385.0
HKD2_k127_2753729_9 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 356.0
HKD2_k127_2768780_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 4.218e-210 669.0
HKD2_k127_2768780_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 425.0
HKD2_k127_2768780_10 Intracellular proteinase inhibitor - - - 0.00000000000006438 84.0
HKD2_k127_2768780_11 - - - - 0.000000001665 59.0
HKD2_k127_2768780_12 - - - - 0.000001994 54.0
HKD2_k127_2768780_13 Psort location CytoplasmicMembrane, score - - - 0.000007325 57.0
HKD2_k127_2768780_2 Zinc-binding dehydrogenase K12957 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 332.0
HKD2_k127_2768780_3 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 260.0
HKD2_k127_2768780_4 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001134 241.0
HKD2_k127_2768780_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000003283 237.0
HKD2_k127_2768780_6 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000001237 235.0
HKD2_k127_2768780_7 epimerase - - - 0.000000000000000000000000000000000000000000000000000008523 196.0
HKD2_k127_2768780_8 Protein tyrosine kinase - - - 0.00000000000000000000000000002709 134.0
HKD2_k127_277426_0 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 375.0
HKD2_k127_277426_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005979 256.0
HKD2_k127_277426_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000002371 227.0
HKD2_k127_2783910_0 Domain of unknown function (DUF1846) - - - 1.461e-213 674.0
HKD2_k127_2783910_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000007146 164.0
HKD2_k127_2800988_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 455.0
HKD2_k127_2800988_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 428.0
HKD2_k127_2800988_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 380.0
HKD2_k127_2800988_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000009825 215.0
HKD2_k127_2800988_4 - - - - 0.00000000000000000000000000000000000000000000000000003361 199.0
HKD2_k127_2800988_5 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000000001694 179.0
HKD2_k127_2800988_6 oxidoreductase activity - - - 0.000000000000000000009568 107.0
HKD2_k127_2800988_7 bacterial OsmY and nodulation domain - - - 0.00000000000000133 85.0
HKD2_k127_2800988_8 oxidoreductase activity - - - 0.000000000000004892 90.0
HKD2_k127_2800988_9 Transcriptional regulator K03724 - - 0.0000000002409 70.0
HKD2_k127_2853028_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 484.0
HKD2_k127_2853028_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 337.0
HKD2_k127_2853028_2 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000849 212.0
HKD2_k127_2853028_3 secreted acid phosphatase - - - 0.00000000000000000000000001136 119.0
HKD2_k127_2853028_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000002945 62.0
HKD2_k127_2867104_0 Sulfatase K01130 - 3.1.6.1 1.861e-199 638.0
HKD2_k127_2867104_1 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004036 271.0
HKD2_k127_2867104_2 Protein of unknown function (DUF2490) - - - 0.00001351 55.0
HKD2_k127_2870723_0 alanine dehydrogenase K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 304.0
HKD2_k127_2870723_1 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000007103 251.0
HKD2_k127_2885392_0 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 477.0
HKD2_k127_2885392_1 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
HKD2_k127_288987_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 503.0
HKD2_k127_288987_1 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 488.0
HKD2_k127_288987_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002954 246.0
HKD2_k127_288987_11 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
HKD2_k127_288987_12 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
HKD2_k127_288987_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000003346 175.0
HKD2_k127_288987_14 HD domain - - - 0.00000000000000000000000000000000000000002094 173.0
HKD2_k127_288987_15 response to abiotic stimulus - - - 0.0000000000000000000000000000000000001285 160.0
HKD2_k127_288987_16 - - - - 0.000000000001091 80.0
HKD2_k127_288987_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 461.0
HKD2_k127_288987_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 412.0
HKD2_k127_288987_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 377.0
HKD2_k127_288987_5 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 396.0
HKD2_k127_288987_6 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
HKD2_k127_288987_7 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 334.0
HKD2_k127_288987_8 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 321.0
HKD2_k127_288987_9 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD2_k127_2922761_0 Belongs to the 'phage' integrase family - - - 2.346e-200 639.0
HKD2_k127_2922761_1 PFAM IS66 Orf2 family protein K07484 - - 0.00000000000000000000000000000000000000000000000000507 190.0
HKD2_k127_2922761_2 Transposase - - - 0.000000000000003777 75.0
HKD2_k127_2922761_3 - - - - 0.00000002821 61.0
HKD2_k127_2922761_4 Rhodopirellula transposase DDE domain - - - 0.000009229 49.0
HKD2_k127_2922761_5 SWIM zinc finger - - - 0.0006898 49.0
HKD2_k127_2947639_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 9.598e-218 690.0
HKD2_k127_2947639_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000749 294.0
HKD2_k127_2947639_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000001128 185.0
HKD2_k127_2947639_3 phosphonate ABC transporter, periplasmic phosphonate binding protein K02044 - - 0.0000000000000000000000000000000000000000000007053 177.0
HKD2_k127_2947639_4 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000003451 73.0
HKD2_k127_2947639_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000855 72.0
HKD2_k127_2947639_6 Redoxin K03386 - 1.11.1.15 0.0002089 49.0
HKD2_k127_2962158_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000001045 202.0
HKD2_k127_2962158_1 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000000000001854 207.0
HKD2_k127_2962158_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000002531 169.0
HKD2_k127_2996745_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 340.0
HKD2_k127_3008104_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.63e-286 916.0
HKD2_k127_3008104_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.111e-220 693.0
HKD2_k127_3008104_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.144e-210 666.0
HKD2_k127_3008104_3 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 597.0
HKD2_k127_3008104_4 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 338.0
HKD2_k127_3008104_5 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 291.0
HKD2_k127_3008104_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000003379 233.0
HKD2_k127_3008104_7 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000137 196.0
HKD2_k127_3008104_8 Thioesterase superfamily - - - 0.0000000000000009818 83.0
HKD2_k127_3024179_0 hydrogenase large subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 342.0
HKD2_k127_3024179_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 320.0
HKD2_k127_3024179_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 298.0
HKD2_k127_3024179_3 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
HKD2_k127_3024179_4 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002221 299.0
HKD2_k127_3024179_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD2_k127_3024179_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000001229 209.0
HKD2_k127_3024179_7 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000005334 116.0
HKD2_k127_3024179_8 hydrogenase maturation protease K03605 - - 0.0000000000000007576 91.0
HKD2_k127_3024179_9 Radical SAM K06871 - - 0.000000001246 70.0
HKD2_k127_3063003_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 420.0
HKD2_k127_3063003_1 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003974 279.0
HKD2_k127_3063003_10 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000003536 100.0
HKD2_k127_3063003_11 Bacterial membrane protein, YfhO - - - 0.0000000000000000000004057 113.0
HKD2_k127_3063003_12 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000005083 98.0
HKD2_k127_3063003_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000583 278.0
HKD2_k127_3063003_3 Esterase-like activity of phytase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000003313 280.0
HKD2_k127_3063003_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000005003 226.0
HKD2_k127_3063003_5 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000001948 149.0
HKD2_k127_3063003_6 BMC K04027 - - 0.000000000000000000000000000000001797 132.0
HKD2_k127_3063003_7 Tetratricopeptide repeat - - - 0.000000000000000000000001059 115.0
HKD2_k127_3063003_8 TIGRFAM TonB K03832 - - 0.000000000000000000000001435 113.0
HKD2_k127_3063003_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000273 106.0
HKD2_k127_3098866_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 441.0
HKD2_k127_3098866_1 Outer membrane protein beta-barrel family K16087,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000003715 236.0
HKD2_k127_3098866_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000001518 73.0
HKD2_k127_3098866_3 aminopeptidase - - - 0.00000008984 57.0
HKD2_k127_3197548_0 transferase activity, transferring acyl groups - - - 0.0000000000000000000009085 107.0
HKD2_k127_3224880_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 5.865e-216 695.0
HKD2_k127_3224880_1 Carboxypeptidase regulatory-like domain - - - 3.489e-207 677.0
HKD2_k127_3224880_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 418.0
HKD2_k127_3224880_3 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003159 228.0
HKD2_k127_3224880_4 Acetyltransferase (GNAT) domain - - - 0.000000000000004783 87.0
HKD2_k127_3254433_0 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001109 273.0
HKD2_k127_3254433_1 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001422 252.0
HKD2_k127_3254433_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000009887 210.0
HKD2_k127_3254433_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000013 142.0
HKD2_k127_3254433_4 Aminotransferase, class I - - - 0.0002544 44.0
HKD2_k127_329500_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 497.0
HKD2_k127_329500_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 311.0
HKD2_k127_329500_10 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000003445 116.0
HKD2_k127_329500_11 Membrane - - - 0.0000002456 62.0
HKD2_k127_329500_12 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.00001161 59.0
HKD2_k127_329500_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 306.0
HKD2_k127_329500_3 Belongs to the LTA synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001618 303.0
HKD2_k127_329500_4 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003676 287.0
HKD2_k127_329500_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD2_k127_329500_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000005556 177.0
HKD2_k127_329500_7 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000005751 165.0
HKD2_k127_329500_8 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions K01519 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000002041 137.0
HKD2_k127_329500_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000002513 129.0
HKD2_k127_336569_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 419.0
HKD2_k127_336569_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 319.0
HKD2_k127_336569_2 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004158 288.0
HKD2_k127_336569_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000004913 236.0
HKD2_k127_336569_4 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000001901 178.0
HKD2_k127_336569_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000001708 168.0
HKD2_k127_337024_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 392.0
HKD2_k127_337024_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 357.0
HKD2_k127_337024_2 anaphase-promoting complex binding - - - 0.000000002028 63.0
HKD2_k127_3391041_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 475.0
HKD2_k127_3391041_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
HKD2_k127_3391041_2 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 350.0
HKD2_k127_3391041_3 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001888 282.0
HKD2_k127_3391041_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000006802 148.0
HKD2_k127_3391041_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000881 108.0
HKD2_k127_3407490_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 300.0
HKD2_k127_3407490_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000004968 119.0
HKD2_k127_3407490_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000004411 125.0
HKD2_k127_351625_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 312.0
HKD2_k127_351625_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HKD2_k127_351625_2 - - - - 0.000000008812 67.0
HKD2_k127_351625_3 - - - - 0.000002289 61.0
HKD2_k127_38299_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.271e-246 798.0
HKD2_k127_38299_1 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 437.0
HKD2_k127_38299_2 peptidase inhibitor activity - - - 0.00000000000000001486 92.0
HKD2_k127_38299_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000363 75.0
HKD2_k127_3844781_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1272.0
HKD2_k127_3844781_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1076.0
HKD2_k127_3844781_10 Allophanate hydrolase subunit 2 K01457,K01941 - 3.5.1.54,6.3.4.6 0.000000000000000000000000000000002284 133.0
HKD2_k127_3844781_11 Protease prsW family - - - 0.000000000000000000000000000000199 138.0
HKD2_k127_3844781_12 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000001305 117.0
HKD2_k127_3844781_13 transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.000000000000000000005728 97.0
HKD2_k127_3844781_14 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002091 104.0
HKD2_k127_3844781_15 pfam yhs - - - 0.000000000005794 68.0
HKD2_k127_3844781_17 - - - - 0.00005327 53.0
HKD2_k127_3844781_2 amine dehydrogenase activity - - - 7.174e-245 789.0
HKD2_k127_3844781_3 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 505.0
HKD2_k127_3844781_4 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
HKD2_k127_3844781_5 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009672 274.0
HKD2_k127_3844781_6 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.00000000000000000000000000000000000000000000000000000000000001673 232.0
HKD2_k127_3844781_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000008848 216.0
HKD2_k127_3844781_8 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD2_k127_3844781_9 DegV family - - - 0.00000000000000000000000000000000000000000000000001898 201.0
HKD2_k127_3844786_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 359.0
HKD2_k127_3844786_1 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000004044 180.0
HKD2_k127_3844786_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000001449 102.0
HKD2_k127_3849304_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.77e-239 749.0
HKD2_k127_3849304_1 Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 493.0
HKD2_k127_3849304_2 Zn-dependent proteases and their inactivated homologs K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000004505 81.0
HKD2_k127_3907334_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 581.0
HKD2_k127_3907334_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 404.0
HKD2_k127_3907334_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000006015 140.0
HKD2_k127_3907334_11 Protein of unknown function (DUF4013) - - - 0.00001877 56.0
HKD2_k127_3907334_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 336.0
HKD2_k127_3907334_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 351.0
HKD2_k127_3907334_4 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
HKD2_k127_3907334_5 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000001604 237.0
HKD2_k127_3907334_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000008093 233.0
HKD2_k127_3907334_7 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD2_k127_3907334_8 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000005594 174.0
HKD2_k127_3907334_9 oxidase subunit K08738 - - 0.00000000000000000000000000000000000000000001849 175.0
HKD2_k127_3914096_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000008845 191.0
HKD2_k127_3914096_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000774 165.0
HKD2_k127_3925219_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 398.0
HKD2_k127_3925219_1 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
HKD2_k127_3925219_2 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000001244 173.0
HKD2_k127_3925219_3 O-antigen ligase like membrane protein - - - 0.000000000000000000000000692 120.0
HKD2_k127_3985719_0 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 423.0
HKD2_k127_4002654_0 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 469.0
HKD2_k127_4016568_0 SMART Elongator protein 3 MiaB NifB - - - 2.827e-238 762.0
HKD2_k127_4016568_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.111e-228 737.0
HKD2_k127_4016568_10 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001963 262.0
HKD2_k127_4016568_11 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000006523 235.0
HKD2_k127_4016568_12 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
HKD2_k127_4016568_13 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000003031 176.0
HKD2_k127_4016568_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000002679 171.0
HKD2_k127_4016568_15 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000001979 166.0
HKD2_k127_4016568_16 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000004765 140.0
HKD2_k127_4016568_17 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000006225 93.0
HKD2_k127_4016568_18 Fibronectin type 3 domain - - - 0.0000000000000001747 92.0
HKD2_k127_4016568_2 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 500.0
HKD2_k127_4016568_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 477.0
HKD2_k127_4016568_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 466.0
HKD2_k127_4016568_5 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 394.0
HKD2_k127_4016568_6 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 289.0
HKD2_k127_4016568_7 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001039 306.0
HKD2_k127_4016568_8 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 264.0
HKD2_k127_4016568_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003043 265.0
HKD2_k127_4044052_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 593.0
HKD2_k127_4049860_0 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 610.0
HKD2_k127_4049860_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 614.0
HKD2_k127_4049860_10 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000009344 274.0
HKD2_k127_4049860_11 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
HKD2_k127_4049860_12 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000006009 233.0
HKD2_k127_4049860_13 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000008964 227.0
HKD2_k127_4049860_14 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000001011 214.0
HKD2_k127_4049860_15 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000244 173.0
HKD2_k127_4049860_16 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000002233 138.0
HKD2_k127_4049860_17 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000001399 137.0
HKD2_k127_4049860_18 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000034 116.0
HKD2_k127_4049860_19 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000008559 112.0
HKD2_k127_4049860_2 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 504.0
HKD2_k127_4049860_20 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000477 111.0
HKD2_k127_4049860_21 Protein of unknown function (DUF2721) - - - 0.00000000000000005848 94.0
HKD2_k127_4049860_22 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.0000000000000005561 78.0
HKD2_k127_4049860_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 434.0
HKD2_k127_4049860_4 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
HKD2_k127_4049860_5 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 401.0
HKD2_k127_4049860_6 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 398.0
HKD2_k127_4049860_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 402.0
HKD2_k127_4049860_8 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 383.0
HKD2_k127_4049860_9 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 290.0
HKD2_k127_4102128_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 415.0
HKD2_k127_4102128_2 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000005654 164.0
HKD2_k127_4102128_3 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000247 126.0
HKD2_k127_412830_0 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 468.0
HKD2_k127_412830_1 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 353.0
HKD2_k127_412830_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000001959 136.0
HKD2_k127_412830_3 - - - - 0.00000000000000000000000002268 125.0
HKD2_k127_412830_4 - - - - 0.00000000000000007621 83.0
HKD2_k127_417768_0 COG1606 ATP-utilizing enzymes of the PP-loop superfamily K06864 - - 0.00000000000000000000000000000000000000000000000000000001231 203.0
HKD2_k127_417768_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000001389 194.0
HKD2_k127_4182019_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 497.0
HKD2_k127_4182019_1 oligopeptide transport K03305 - - 0.00000000000000000000000000000000001248 139.0
HKD2_k127_4182019_2 - - - - 0.000000000002773 81.0
HKD2_k127_4234744_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 562.0
HKD2_k127_4234744_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 309.0
HKD2_k127_4234744_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
HKD2_k127_4234744_3 isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000001702 232.0
HKD2_k127_4234744_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000003348 189.0
HKD2_k127_4234744_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000009703 86.0
HKD2_k127_4234744_6 Outer membrane lipoprotein carrier protein LolA - - - 0.00001949 54.0
HKD2_k127_4239997_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.556e-264 842.0
HKD2_k127_4239997_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 563.0
HKD2_k127_4239997_2 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000003218 228.0
HKD2_k127_4239997_3 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000006353 188.0
HKD2_k127_4239997_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000002264 94.0
HKD2_k127_4239997_5 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000004843 92.0
HKD2_k127_4239997_6 involved in lipopolysaccharide - - - 0.000000003721 57.0
HKD2_k127_4259887_0 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 497.0
HKD2_k127_4259887_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 437.0
HKD2_k127_4259887_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 374.0
HKD2_k127_4259887_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 381.0
HKD2_k127_4259887_4 Putative esterase - - - 0.0004795 46.0
HKD2_k127_4332041_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 296.0
HKD2_k127_4332041_1 Bacterial membrane protein YfhO - - - 0.0000000000000000356 95.0
HKD2_k127_4332041_2 Alpha/beta hydrolase family - - - 0.0008731 44.0
HKD2_k127_4363206_0 N,N-dimethylaniline monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 521.0
HKD2_k127_4363206_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000004966 172.0
HKD2_k127_4363206_2 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000001055 168.0
HKD2_k127_4363206_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000003284 78.0
HKD2_k127_4425370_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 422.0
HKD2_k127_4425370_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 366.0
HKD2_k127_4425370_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000003375 122.0
HKD2_k127_4425370_11 transporter K07238,K11021 - - 0.00000000000000000000005939 108.0
HKD2_k127_4425370_12 Peptidase family M23 K21471 - - 0.0000000000000000000006758 111.0
HKD2_k127_4425370_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000002322 94.0
HKD2_k127_4425370_14 Neuraminyllactose-binding hemagglutinin precursor (NLBH) K15846 - - 0.0000000005242 70.0
HKD2_k127_4425370_15 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit K04762 - - 0.000000002103 69.0
HKD2_k127_4425370_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 310.0
HKD2_k127_4425370_3 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000667 288.0
HKD2_k127_4425370_4 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000001727 186.0
HKD2_k127_4425370_5 Beta-lactamase - - - 0.0000000000000000000000000000000000000000001612 182.0
HKD2_k127_4425370_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000264 175.0
HKD2_k127_4425370_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000007883 166.0
HKD2_k127_4425370_8 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000007589 162.0
HKD2_k127_4425370_9 OsmC-like protein K07397 - - 0.000000000000000000000000001513 117.0
HKD2_k127_4427279_0 Cation transporter/ATPase, N-terminus K01531,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 2.724e-258 803.0
HKD2_k127_4427279_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 465.0
HKD2_k127_4427279_2 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 370.0
HKD2_k127_4427279_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 295.0
HKD2_k127_4427279_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000003818 113.0
HKD2_k127_4427279_5 Beta-lactamase superfamily domain - - - 0.000000000000000000004117 106.0
HKD2_k127_4474458_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 363.0
HKD2_k127_4474458_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000001506 231.0
HKD2_k127_4474458_2 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000001382 193.0
HKD2_k127_4474458_3 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000003922 151.0
HKD2_k127_4497735_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 476.0
HKD2_k127_4497735_1 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000001033 176.0
HKD2_k127_4497735_2 Predicted permease K07089 - - 0.0000000000000003907 81.0
HKD2_k127_4497735_3 regulatory protein, arsR K03892 - - 0.00000000000008852 78.0
HKD2_k127_4497735_4 - - - - 0.0000000003083 68.0
HKD2_k127_4516645_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.664e-217 697.0
HKD2_k127_4516645_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 499.0
HKD2_k127_4516645_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
HKD2_k127_4516645_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 319.0
HKD2_k127_4516645_4 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 317.0
HKD2_k127_4516645_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008218 286.0
HKD2_k127_4516645_6 Pilus assembly protein, PilO K02664 - - 0.000000000000000000002533 105.0
HKD2_k127_4516645_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000003513 86.0
HKD2_k127_4516645_8 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000008223 86.0
HKD2_k127_4516645_9 Fimbrial assembly protein (PilN) K02663 - - 0.00000000264 66.0
HKD2_k127_4558519_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.866e-194 629.0
HKD2_k127_4558519_1 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HKD2_k127_4558519_2 PFAM DNA repair protein RadC K03630 - - 0.0000000000000000000000000000000000000000000000001101 186.0
HKD2_k127_4558519_3 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000007442 171.0
HKD2_k127_4558519_4 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000007214 142.0
HKD2_k127_4558519_5 Psort location CytoplasmicMembrane, score K07088 - - 0.000000000000000000000000000004493 134.0
HKD2_k127_4558519_6 - - - - 0.0000000000000000000001113 100.0
HKD2_k127_4558519_7 Transglycosylase associated protein - - - 0.000000000000000000001022 97.0
HKD2_k127_4558519_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000007684 78.0
HKD2_k127_4623537_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
HKD2_k127_4623537_1 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 401.0
HKD2_k127_4623537_10 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000002386 145.0
HKD2_k127_4623537_11 metal-sulfur cluster biosynthetic - - - 0.000000000000000000000009214 105.0
HKD2_k127_4623537_12 PFAM YbbR family protein - - - 0.00000000000000000000545 105.0
HKD2_k127_4623537_13 Belongs to the universal stress protein A family - - - 0.0000000000000000000829 96.0
HKD2_k127_4623537_14 DSBA-like thioredoxin domain - - - 0.00000000000000002023 95.0
HKD2_k127_4623537_15 protein kinase activity - - - 0.0000000000000003725 93.0
HKD2_k127_4623537_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 342.0
HKD2_k127_4623537_3 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 295.0
HKD2_k127_4623537_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000004528 255.0
HKD2_k127_4623537_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000005227 214.0
HKD2_k127_4623537_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000002196 220.0
HKD2_k127_4623537_7 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000001691 196.0
HKD2_k127_4623537_8 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000001439 180.0
HKD2_k127_4623537_9 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000001821 157.0
HKD2_k127_464763_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 565.0
HKD2_k127_464763_1 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 554.0
HKD2_k127_464763_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 477.0
HKD2_k127_464763_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
HKD2_k127_464763_4 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 449.0
HKD2_k127_464763_5 Glycosyl transferases group 1 - - - 0.000000000000000000000003809 106.0
HKD2_k127_489229_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 498.0
HKD2_k127_4933819_0 translation release factor activity - - - 0.000000000000000000000000000000000000000000000883 180.0
HKD2_k127_4982610_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 460.0
HKD2_k127_4982610_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000002321 225.0
HKD2_k127_4982610_10 Domain of unknown function (DUF4398) - - - 0.00002196 55.0
HKD2_k127_4982610_2 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000001759 234.0
HKD2_k127_4982610_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000192 181.0
HKD2_k127_4982610_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000003105 178.0
HKD2_k127_4982610_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004945 184.0
HKD2_k127_4982610_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001147 169.0
HKD2_k127_4982610_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000000001748 129.0
HKD2_k127_4982610_8 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000001318 110.0
HKD2_k127_4982610_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000002613 80.0
HKD2_k127_503817_0 oxidoreductase activity - - - 0.0000000000002477 83.0
HKD2_k127_503817_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000003291 63.0
HKD2_k127_507325_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 433.0
HKD2_k127_507325_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007479 279.0
HKD2_k127_507325_2 Chaperone of endosialidase - - - 0.000000000000000000000000000000000000000000000009545 194.0
HKD2_k127_507325_3 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000001308 144.0
HKD2_k127_5115142_0 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 561.0
HKD2_k127_5115142_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 446.0
HKD2_k127_5115142_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000004269 243.0
HKD2_k127_5115142_3 response to abiotic stimulus - - - 0.000000000000000000000000000000000000001255 160.0
HKD2_k127_5115142_4 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000001937 104.0
HKD2_k127_5115142_5 CotH kinase protein - - - 0.000004728 58.0
HKD2_k127_5115142_6 peptide catabolic process K01256 - 3.4.11.2 0.0004005 51.0
HKD2_k127_5141773_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 347.0
HKD2_k127_5141773_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
HKD2_k127_5141773_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000002094 124.0
HKD2_k127_5150897_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
HKD2_k127_5150897_1 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 344.0
HKD2_k127_5150897_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
HKD2_k127_5150897_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001556 229.0
HKD2_k127_5150897_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000006046 211.0
HKD2_k127_5150897_5 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.0000000000000000003095 97.0
HKD2_k127_5150897_6 PspC domain K03973 - - 0.0000000002572 68.0
HKD2_k127_5152877_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.168e-239 747.0
HKD2_k127_5152877_1 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 388.0
HKD2_k127_5152877_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000008418 59.0
HKD2_k127_5152877_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00003329 51.0
HKD2_k127_5152949_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000001381 241.0
HKD2_k127_5152949_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000764 226.0
HKD2_k127_5152949_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000002162 206.0
HKD2_k127_5152949_3 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.0000000004998 71.0
HKD2_k127_5161671_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 627.0
HKD2_k127_5161671_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 554.0
HKD2_k127_5172207_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001749 203.0
HKD2_k127_5172207_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000006915 200.0
HKD2_k127_5172207_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000001334 98.0
HKD2_k127_5179412_0 pyrophosphate-energized membrane proton pump K01507 - 3.6.1.1 2.891e-286 897.0
HKD2_k127_5179412_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.339e-265 848.0
HKD2_k127_5179412_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 335.0
HKD2_k127_5179412_11 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD2_k127_5179412_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 329.0
HKD2_k127_5179412_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003652 294.0
HKD2_k127_5179412_14 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000005936 234.0
HKD2_k127_5179412_15 Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000009323 174.0
HKD2_k127_5179412_16 - - - - 0.0000000000000000000000000000000000000009887 158.0
HKD2_k127_5179412_17 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000004097 156.0
HKD2_k127_5179412_18 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000001519 122.0
HKD2_k127_5179412_19 Transport and Golgi organisation 2 - - - 0.000000000000000000000000002273 121.0
HKD2_k127_5179412_2 carboxypeptidase - - - 1.046e-209 684.0
HKD2_k127_5179412_20 NifU-like domain - - - 0.0000000000000000003807 94.0
HKD2_k127_5179412_21 - - - - 0.00000003348 62.0
HKD2_k127_5179412_22 Protein of unknown function (DUF2905) - - - 0.00000003593 61.0
HKD2_k127_5179412_23 Modulates RecA activity K03565 - - 0.00000006013 61.0
HKD2_k127_5179412_24 ECF sigma factor K03088 - - 0.0000001206 59.0
HKD2_k127_5179412_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000579 59.0
HKD2_k127_5179412_26 Domain of unknown function (DUF4412) - - - 0.000002305 59.0
HKD2_k127_5179412_27 Acetyltransferase (GNAT) domain - - - 0.00003979 53.0
HKD2_k127_5179412_3 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 571.0
HKD2_k127_5179412_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
HKD2_k127_5179412_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 485.0
HKD2_k127_5179412_6 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 437.0
HKD2_k127_5179412_7 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 424.0
HKD2_k127_5179412_8 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 400.0
HKD2_k127_5179412_9 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 353.0
HKD2_k127_5199655_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 366.0
HKD2_k127_5199655_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 358.0
HKD2_k127_5208622_0 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 459.0
HKD2_k127_5208622_1 TIGRFAM maf protein K06287 - - 0.0000000000000000000000000000000000000007505 157.0
HKD2_k127_5208622_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001373 140.0
HKD2_k127_5208622_3 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000002305 136.0
HKD2_k127_5208622_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000002714 134.0
HKD2_k127_5208622_5 - - - - 0.000000000000000000000000002701 113.0
HKD2_k127_5208622_6 family UPF0066 K01628 - 4.1.2.17 0.00000000000000002447 89.0
HKD2_k127_5208622_7 Outer membrane efflux protein - - - 0.00000000000000003206 93.0
HKD2_k127_5208622_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000002712 81.0
HKD2_k127_5208622_9 - - - - 0.00002731 55.0
HKD2_k127_5227706_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 2.253e-198 629.0
HKD2_k127_5227706_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 385.0
HKD2_k127_5227706_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001321 237.0
HKD2_k127_5227706_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
HKD2_k127_5227706_12 Ribosomal protein L16p/L10e K02878 - - 0.000000000000000000000000000000000000000000000000000000000000002184 223.0
HKD2_k127_5227706_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001035 203.0
HKD2_k127_5227706_14 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000235 191.0
HKD2_k127_5227706_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002091 192.0
HKD2_k127_5227706_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000006152 195.0
HKD2_k127_5227706_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000008579 178.0
HKD2_k127_5227706_18 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000123 181.0
HKD2_k127_5227706_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000001455 176.0
HKD2_k127_5227706_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 369.0
HKD2_k127_5227706_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000006196 174.0
HKD2_k127_5227706_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000001063 165.0
HKD2_k127_5227706_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000003839 148.0
HKD2_k127_5227706_23 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000004642 169.0
HKD2_k127_5227706_24 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004225 139.0
HKD2_k127_5227706_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000001308 136.0
HKD2_k127_5227706_26 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001709 133.0
HKD2_k127_5227706_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000002558 129.0
HKD2_k127_5227706_28 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000005369 131.0
HKD2_k127_5227706_29 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000002369 130.0
HKD2_k127_5227706_3 Dihydroxyacetone kinase family K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 367.0
HKD2_k127_5227706_30 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000486 124.0
HKD2_k127_5227706_31 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000008245 115.0
HKD2_k127_5227706_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000001779 107.0
HKD2_k127_5227706_33 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000001207 100.0
HKD2_k127_5227706_34 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000004407 101.0
HKD2_k127_5227706_35 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000003026 93.0
HKD2_k127_5227706_36 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000009021 76.0
HKD2_k127_5227706_37 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000118 73.0
HKD2_k127_5227706_38 Ribosomal protein L36 K02919 - - 0.0000000000002467 70.0
HKD2_k127_5227706_4 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 363.0
HKD2_k127_5227706_40 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000001319 59.0
HKD2_k127_5227706_41 TIGRFAM TonB family C-terminal domain K03832 - - 0.000004479 59.0
HKD2_k127_5227706_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HKD2_k127_5227706_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 293.0
HKD2_k127_5227706_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 304.0
HKD2_k127_5227706_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
HKD2_k127_5227706_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001422 245.0
HKD2_k127_5232023_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 598.0
HKD2_k127_5232023_1 Peptidase dimerisation domain K01451 - 3.5.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 492.0
HKD2_k127_5232023_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000001421 149.0
HKD2_k127_5232023_11 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000002615 147.0
HKD2_k127_5232023_12 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000004331 139.0
HKD2_k127_5232023_13 Protein of unknown function DUF58 - - - 0.00000000000000000000000001507 122.0
HKD2_k127_5232023_14 PAP2 superfamily - - - 0.0000000000000000000000003405 117.0
HKD2_k127_5232023_15 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000001005 106.0
HKD2_k127_5232023_16 Pilus assembly protein, PilP - - - 0.00000000000000842 79.0
HKD2_k127_5232023_17 Bacterial SH3 domain K01876 - 6.1.1.12 0.00006317 55.0
HKD2_k127_5232023_18 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00038 53.0
HKD2_k127_5232023_2 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 505.0
HKD2_k127_5232023_3 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 339.0
HKD2_k127_5232023_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 327.0
HKD2_k127_5232023_5 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 297.0
HKD2_k127_5232023_6 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
HKD2_k127_5232023_7 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000799 190.0
HKD2_k127_5232023_8 DoxX K15977 - - 0.00000000000000000000000000000000000000000000001822 175.0
HKD2_k127_5232023_9 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000709 156.0
HKD2_k127_5234868_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 454.0
HKD2_k127_5234868_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 425.0
HKD2_k127_5234868_10 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.0000000000000000000000006938 111.0
HKD2_k127_5234868_11 Glycine cleavage H-protein - - - 0.000000000000000000019 100.0
HKD2_k127_5234868_12 zinc metalloprotease whose natural substrate is K06974 - - 0.0000000000000000000614 96.0
HKD2_k127_5234868_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 387.0
HKD2_k127_5234868_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 374.0
HKD2_k127_5234868_4 Transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003197 289.0
HKD2_k127_5234868_5 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003794 248.0
HKD2_k127_5234868_6 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000648 216.0
HKD2_k127_5234868_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000005387 192.0
HKD2_k127_5234868_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000001968 170.0
HKD2_k127_5234868_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000004039 110.0
HKD2_k127_5235163_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 355.0
HKD2_k127_5235163_1 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 302.0
HKD2_k127_5235163_2 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003729 286.0
HKD2_k127_5235163_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000009736 265.0
HKD2_k127_5235163_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004078 264.0
HKD2_k127_5235163_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000007101 244.0
HKD2_k127_5235163_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000001409 213.0
HKD2_k127_5235361_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1148.0
HKD2_k127_5235361_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1063.0
HKD2_k127_5235361_10 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000002328 166.0
HKD2_k127_5235361_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000293 157.0
HKD2_k127_5235361_12 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000002466 142.0
HKD2_k127_5235361_13 DRTGG domain - - - 0.00000000000000000008283 103.0
HKD2_k127_5235361_14 B3/4 domain - - - 0.000000000000000001632 97.0
HKD2_k127_5235361_16 - - - - 0.00000000003087 70.0
HKD2_k127_5235361_17 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000661 61.0
HKD2_k127_5235361_18 DRTGG domain - - - 0.00000004236 59.0
HKD2_k127_5235361_2 Response regulator, receiver K01007 - 2.7.9.2 2.099e-245 791.0
HKD2_k127_5235361_3 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.212e-243 773.0
HKD2_k127_5235361_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.685e-210 663.0
HKD2_k127_5235361_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.205e-194 624.0
HKD2_k127_5235361_6 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 556.0
HKD2_k127_5235361_7 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 319.0
HKD2_k127_5235361_8 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 310.0
HKD2_k127_5235361_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000007115 181.0
HKD2_k127_5245165_0 mannose metabolic process K01191 - 3.2.1.24 1.773e-291 940.0
HKD2_k127_5245165_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 436.0
HKD2_k127_5253505_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 7.123e-201 636.0
HKD2_k127_5253505_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 364.0
HKD2_k127_5253505_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000004421 139.0
HKD2_k127_5276151_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 572.0
HKD2_k127_5276151_1 KR domain - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000002598 101.0
HKD2_k127_5287699_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.836e-289 908.0
HKD2_k127_5287699_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.46e-197 624.0
HKD2_k127_5287699_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 553.0
HKD2_k127_5287699_3 Ferrous iron transport protein B K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000009105 151.0
HKD2_k127_5287699_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000009532 86.0
HKD2_k127_5326589_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 297.0
HKD2_k127_5326589_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K03561,K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000007879 265.0
HKD2_k127_532874_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 2.304e-295 929.0
HKD2_k127_532874_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000007446 196.0
HKD2_k127_5329576_0 PFAM ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003589 286.0
HKD2_k127_5329576_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000002434 145.0
HKD2_k127_5329576_2 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000009857 105.0
HKD2_k127_533925_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 511.0
HKD2_k127_533925_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000003097 157.0
HKD2_k127_533925_2 PFAM glycosyl transferase family 39 - - - 0.000003249 55.0
HKD2_k127_533925_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001061 55.0
HKD2_k127_5370593_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000005404 216.0
HKD2_k127_5370593_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000001082 154.0
HKD2_k127_5387174_0 Oligopeptidase F K08602 - - 1.15e-206 663.0
HKD2_k127_5387174_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000009325 242.0
HKD2_k127_5396872_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 425.0
HKD2_k127_5396872_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000004908 107.0
HKD2_k127_5407207_0 Polysulphide reductase K00185 - - 2.217e-216 684.0
HKD2_k127_5407207_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 383.0
HKD2_k127_5407207_2 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 362.0
HKD2_k127_5407207_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 290.0
HKD2_k127_5407207_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HKD2_k127_5407207_5 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000194 211.0
HKD2_k127_5407207_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000003671 139.0
HKD2_k127_5407207_7 - - - - 0.0000009537 55.0
HKD2_k127_5459573_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 324.0
HKD2_k127_5459573_1 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000001449 178.0
HKD2_k127_5459573_2 Domain of unknown function (DUF4214) K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000226 153.0
HKD2_k127_54702_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 429.0
HKD2_k127_54702_1 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 403.0
HKD2_k127_54702_2 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
HKD2_k127_54702_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000002931 118.0
HKD2_k127_54702_4 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000003596 94.0
HKD2_k127_54702_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000005773 100.0
HKD2_k127_5475146_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000009406 146.0
HKD2_k127_5475146_1 - - - - 0.0000000000000000000000000000000005513 134.0
HKD2_k127_5475146_2 Transposase IS200 like - - - 0.00000000000000000000000000002037 130.0
HKD2_k127_5475146_3 PAP2 superfamily - - - 0.00000000000000000000000000006029 132.0
HKD2_k127_5480343_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005622 289.0
HKD2_k127_5480343_1 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003523 246.0
HKD2_k127_5480343_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.00000000001711 66.0
HKD2_k127_5480343_11 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000004425 61.0
HKD2_k127_5480343_12 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0001059 54.0
HKD2_k127_5480343_13 PFAM response regulator receiver - - - 0.0009052 47.0
HKD2_k127_5480343_2 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
HKD2_k127_5480343_3 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000008401 198.0
HKD2_k127_5480343_4 AP endonuclease family 2 K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000006472 179.0
HKD2_k127_5480343_5 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000003308 180.0
HKD2_k127_5480343_6 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000008107 143.0
HKD2_k127_5480343_7 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000421 105.0
HKD2_k127_5480343_8 phosphotransferase related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000003093 108.0
HKD2_k127_5480343_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000002862 98.0
HKD2_k127_5538638_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 412.0
HKD2_k127_5583198_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 428.0
HKD2_k127_5592820_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 495.0
HKD2_k127_5592820_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 481.0
HKD2_k127_5592820_10 - - - - 0.000000000008834 76.0
HKD2_k127_5592820_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 398.0
HKD2_k127_5592820_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009762 264.0
HKD2_k127_5592820_4 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000002644 250.0
HKD2_k127_5592820_5 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000512 226.0
HKD2_k127_5592820_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000002438 195.0
HKD2_k127_5592820_7 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000658 187.0
HKD2_k127_5592820_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000269 178.0
HKD2_k127_5594918_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 1.983e-209 668.0
HKD2_k127_5594918_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 359.0
HKD2_k127_5594918_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 326.0
HKD2_k127_5594918_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 308.0
HKD2_k127_5594918_4 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 258.0
HKD2_k127_5594918_5 Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000003089 248.0
HKD2_k127_5594918_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
HKD2_k127_5594918_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000005315 96.0
HKD2_k127_5594918_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000006816 87.0
HKD2_k127_5606325_0 - - - - 4.617e-258 814.0
HKD2_k127_5606325_1 Alpha-amylase domain K01176 - 3.2.1.1 8.669e-218 691.0
HKD2_k127_5606325_10 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000007011 136.0
HKD2_k127_5606325_11 - - - - 0.0000000000000000000005279 105.0
HKD2_k127_5606325_2 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 428.0
HKD2_k127_5606325_3 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 295.0
HKD2_k127_5606325_4 C-terminal binding-module, SLH-like, of glucodextranase K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002144 272.0
HKD2_k127_5606325_5 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005362 275.0
HKD2_k127_5606325_6 Ras family - - - 0.00000000000000000000000000000000000000000000000000000000002776 230.0
HKD2_k127_5606325_7 DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000003459 216.0
HKD2_k127_5606325_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000007447 198.0
HKD2_k127_5606325_9 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000006877 162.0
HKD2_k127_5618266_0 ArgK protein K11942 - 5.4.99.13 0.0 1243.0
HKD2_k127_5618266_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 531.0
HKD2_k127_5618266_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
HKD2_k127_5618266_3 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 291.0
HKD2_k127_5618266_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000009054 251.0
HKD2_k127_5618266_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000001145 229.0
HKD2_k127_5618266_6 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000001758 166.0
HKD2_k127_5626223_0 Doxx family K15977 - - 0.00000000000000000000000000000000000000000000006773 173.0
HKD2_k127_5626223_1 L-malate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000003051 179.0
HKD2_k127_5626223_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000007615 124.0
HKD2_k127_5626223_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000003718 104.0
HKD2_k127_5626223_4 Cytidylyltransferase-like - - - 0.0000000000000003818 87.0
HKD2_k127_5628881_0 lysine biosynthetic process via aminoadipic acid - - - 8e-225 719.0
HKD2_k127_5628881_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 443.0
HKD2_k127_5628881_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000001601 123.0
HKD2_k127_5780250_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 8.223e-238 751.0
HKD2_k127_5780250_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 614.0
HKD2_k127_5780250_10 O-Antigen ligase K18814 - - 0.00000000000000000000000000002061 131.0
HKD2_k127_5780250_11 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.000000000000003003 87.0
HKD2_k127_5780250_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000166 88.0
HKD2_k127_5780250_13 Bacterial Ig-like domain - - - 0.0000000000000166 88.0
HKD2_k127_5780250_14 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000001424 84.0
HKD2_k127_5780250_15 Belongs to the UPF0434 family K09791 - - 0.000000000428 68.0
HKD2_k127_5780250_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001195 59.0
HKD2_k127_5780250_2 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 550.0
HKD2_k127_5780250_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 497.0
HKD2_k127_5780250_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 304.0
HKD2_k127_5780250_5 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001025 259.0
HKD2_k127_5780250_6 - - - - 0.00000000000000000000000000000000000000000000000000000000009475 227.0
HKD2_k127_5780250_7 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000006271 198.0
HKD2_k127_5780250_8 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000002414 196.0
HKD2_k127_5780250_9 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000007608 193.0
HKD2_k127_5839552_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 1.796e-249 782.0
HKD2_k127_5839552_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 532.0
HKD2_k127_5839552_2 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002553 296.0
HKD2_k127_5839552_3 DinB family - - - 0.000000000000000000000000000000000000000009398 160.0
HKD2_k127_5839552_4 beta-lactamase - - - 0.00000000000000000000000000001766 130.0
HKD2_k127_5839552_5 GYD domain - - - 0.000000000000000000000003871 108.0
HKD2_k127_5839552_6 - - - - 0.000000000000000000000004087 115.0
HKD2_k127_5839552_7 Sulfatase - - - 0.000000000000000000009912 108.0
HKD2_k127_5839552_8 Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source K05396,K17950 GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0034011,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.4.1.15,4.4.1.25 0.000000002439 61.0
HKD2_k127_5840982_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
HKD2_k127_5840982_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.00006146 55.0
HKD2_k127_589035_0 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 373.0
HKD2_k127_589035_1 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 342.0
HKD2_k127_589035_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000005203 117.0
HKD2_k127_627866_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.4e-221 697.0
HKD2_k127_627866_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 500.0
HKD2_k127_629511_0 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003065 234.0
HKD2_k127_629511_1 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000001243 190.0
HKD2_k127_629511_2 LppP/LprE lipoprotein - - - 0.0000000000000000000000000000000000000000003709 179.0
HKD2_k127_629511_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000001974 111.0
HKD2_k127_629511_4 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000001861 84.0
HKD2_k127_629511_5 Protein of unknown function, DUF481 - - - 0.000000007604 68.0
HKD2_k127_6380615_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 528.0
HKD2_k127_6380615_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000007033 68.0
HKD2_k127_6380615_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001097 66.0
HKD2_k127_6385566_0 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 511.0
HKD2_k127_6385566_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 352.0
HKD2_k127_6385566_2 transport protein CorA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 325.0
HKD2_k127_6385566_3 - - - - 0.0000000000000000000000000001747 127.0
HKD2_k127_6385566_4 Dodecin K09165 - - 0.000000000000000002521 91.0
HKD2_k127_6389165_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HKD2_k127_6389165_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 452.0
HKD2_k127_6389165_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000008888 79.0
HKD2_k127_6389165_11 PFAM Outer membrane efflux protein - - - 0.000000005372 69.0
HKD2_k127_6389165_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 413.0
HKD2_k127_6389165_3 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 343.0
HKD2_k127_6389165_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 311.0
HKD2_k127_6389165_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002379 245.0
HKD2_k127_6389165_6 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000328 250.0
HKD2_k127_6389165_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000001415 119.0
HKD2_k127_6389165_8 Regulatory protein, FmdB - - - 0.000000000000000000000327 99.0
HKD2_k127_6389165_9 Domain of unknown function (DUF4388) - - - 0.0000000000003659 79.0
HKD2_k127_6397242_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1672.0
HKD2_k127_6397242_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1438.0
HKD2_k127_6397242_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002299 118.0
HKD2_k127_6397242_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000009021 76.0
HKD2_k127_6397242_12 Ribosomal protein L33 K02913 - - 0.00000000000002891 75.0
HKD2_k127_6397242_13 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000003468 55.0
HKD2_k127_6397242_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 459.0
HKD2_k127_6397242_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 305.0
HKD2_k127_6397242_4 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HKD2_k127_6397242_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
HKD2_k127_6397242_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD2_k127_6397242_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
HKD2_k127_6397242_8 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000001267 199.0
HKD2_k127_6397242_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000001007 151.0
HKD2_k127_6405387_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 435.0
HKD2_k127_6405387_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 422.0
HKD2_k127_6405387_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006429 300.0
HKD2_k127_6405387_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000006256 238.0
HKD2_k127_6405387_4 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000281 189.0
HKD2_k127_6405387_5 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000003679 78.0
HKD2_k127_6412103_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K04020,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 352.0
HKD2_k127_6412103_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 327.0
HKD2_k127_6412103_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000005619 113.0
HKD2_k127_6420890_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 523.0
HKD2_k127_6420890_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 289.0
HKD2_k127_6420890_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007057 290.0
HKD2_k127_6420890_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
HKD2_k127_6420890_4 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000001406 142.0
HKD2_k127_6420890_5 - - - - 0.0000000000000000000000000000000004234 136.0
HKD2_k127_6420890_6 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000006019 100.0
HKD2_k127_6420890_7 Resolvase - - - 0.0009521 49.0
HKD2_k127_6435481_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 434.0
HKD2_k127_6435481_1 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.00000000000000000000000000000000000000000000000000000000000000001045 233.0
HKD2_k127_6435481_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003624 214.0
HKD2_k127_6435481_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000007517 197.0
HKD2_k127_6435481_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000001097 188.0
HKD2_k127_6435481_5 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000002445 141.0
HKD2_k127_6435481_6 Binds the 23S rRNA K02909 - - 0.000000000000000000000000105 108.0
HKD2_k127_6442745_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 9.434e-255 822.0
HKD2_k127_6442745_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 501.0
HKD2_k127_6442745_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000002713 197.0
HKD2_k127_6442745_3 - - - - 0.000000000000000000000000000000000000000001327 162.0
HKD2_k127_6450060_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1305.0
HKD2_k127_6450060_1 FAD dependent oxidoreductase - - - 2.534e-209 663.0
HKD2_k127_6450060_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 415.0
HKD2_k127_6461795_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 507.0
HKD2_k127_6461795_1 PFAM Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 524.0
HKD2_k127_6461795_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
HKD2_k127_6464424_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1343.0
HKD2_k127_6464424_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000002358 228.0
HKD2_k127_6464424_2 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000006959 179.0
HKD2_k127_6480556_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 2.264e-272 855.0
HKD2_k127_6480556_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 380.0
HKD2_k127_6480556_2 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 330.0
HKD2_k127_6480556_3 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
HKD2_k127_6480556_4 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000006112 207.0
HKD2_k127_6480556_5 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000005114 124.0
HKD2_k127_6480556_6 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000000000000000006507 101.0
HKD2_k127_6480556_7 STAS domain K04749 - - 0.0000000000000001867 83.0
HKD2_k127_6480556_8 - - - - 0.00000000004599 74.0
HKD2_k127_6480556_9 PFAM GGDEF domain containing protein K18968 - 2.7.7.65 0.00008506 49.0
HKD2_k127_6483704_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000002745 168.0
HKD2_k127_6483704_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000008671 124.0
HKD2_k127_6483859_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 431.0
HKD2_k127_6483859_1 NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
HKD2_k127_6483859_10 - - - - 0.00001072 57.0
HKD2_k127_6483859_2 phosphorelay signal transduction system K14987 - - 0.0000000000000000000000000000000000000000000000000000000000002867 224.0
HKD2_k127_6483859_3 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000001298 190.0
HKD2_k127_6483859_4 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000002172 173.0
HKD2_k127_6483859_5 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000008249 143.0
HKD2_k127_6483859_6 PAP2 superfamily - - - 0.00000000000000000000000000000003265 138.0
HKD2_k127_6483859_7 cheY-homologous receiver domain - - - 0.00000000000000000000002146 104.0
HKD2_k127_6483859_9 CAAX protease self-immunity - - - 0.000001771 59.0
HKD2_k127_648598_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
HKD2_k127_648598_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000004753 192.0
HKD2_k127_648598_2 - - - - 0.000000000000002453 82.0
HKD2_k127_6494585_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 564.0
HKD2_k127_6494585_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 428.0
HKD2_k127_6494585_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 404.0
HKD2_k127_6494585_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
HKD2_k127_6494585_4 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
HKD2_k127_6494585_5 Fumarase C-terminus K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
HKD2_k127_6494585_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 244.0
HKD2_k127_6494585_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000000000721 106.0
HKD2_k127_6494585_8 NTPase - - - 0.000000000000000004408 87.0
HKD2_k127_6506144_0 Transposase - - - 7.249e-196 625.0
HKD2_k127_6506144_1 - - - - 0.00000003136 59.0
HKD2_k127_6538944_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
HKD2_k127_6538944_1 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000006127 127.0
HKD2_k127_6538944_2 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000003648 101.0
HKD2_k127_6538944_3 - - - - 0.000000000000003305 82.0
HKD2_k127_6540634_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.548e-281 893.0
HKD2_k127_6540634_1 iron-nicotianamine transmembrane transporter activity - - - 1.711e-220 703.0
HKD2_k127_6540634_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 307.0
HKD2_k127_6540634_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
HKD2_k127_6540634_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
HKD2_k127_6540634_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000004267 270.0
HKD2_k127_6540634_14 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
HKD2_k127_6540634_15 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000002014 262.0
HKD2_k127_6540634_16 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000005367 235.0
HKD2_k127_6540634_17 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000001601 229.0
HKD2_k127_6540634_18 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000005179 227.0
HKD2_k127_6540634_19 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000002987 181.0
HKD2_k127_6540634_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 5.137e-218 691.0
HKD2_k127_6540634_20 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000001526 191.0
HKD2_k127_6540634_21 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000003703 191.0
HKD2_k127_6540634_22 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000004272 168.0
HKD2_k127_6540634_23 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000002691 158.0
HKD2_k127_6540634_24 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000007565 157.0
HKD2_k127_6540634_25 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000001363 162.0
HKD2_k127_6540634_26 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000003908 158.0
HKD2_k127_6540634_27 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000001827 156.0
HKD2_k127_6540634_28 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000004897 139.0
HKD2_k127_6540634_29 von Willebrand factor, type A - - - 0.000000000000000000000000001851 130.0
HKD2_k127_6540634_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 562.0
HKD2_k127_6540634_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000005763 119.0
HKD2_k127_6540634_31 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000001011 112.0
HKD2_k127_6540634_32 Thioredoxin-like - - - 0.0000000000000000001339 96.0
HKD2_k127_6540634_33 PFAM FecR protein - - - 0.0000000000000000006436 100.0
HKD2_k127_6540634_34 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000007326 72.0
HKD2_k127_6540634_35 Involved in formation and maintenance of cell shape K03570 - - 0.000000000001217 79.0
HKD2_k127_6540634_36 Protein of unknown function (DUF2914) - - - 0.000000000002406 78.0
HKD2_k127_6540634_37 outer membrane autotransporter barrel domain protein - - - 0.000000000004079 75.0
HKD2_k127_6540634_38 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000005512 67.0
HKD2_k127_6540634_39 chaperone-mediated protein folding - - - 0.00000004211 67.0
HKD2_k127_6540634_4 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 496.0
HKD2_k127_6540634_40 Belongs to the ompA family K03286 - - 0.0002602 51.0
HKD2_k127_6540634_5 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 472.0
HKD2_k127_6540634_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 426.0
HKD2_k127_6540634_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
HKD2_k127_6540634_8 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 421.0
HKD2_k127_6540634_9 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
HKD2_k127_6541201_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
HKD2_k127_6541201_1 PHP domain protein K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 435.0
HKD2_k127_6541201_10 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001233 280.0
HKD2_k127_6541201_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001103 276.0
HKD2_k127_6541201_12 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HKD2_k127_6541201_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008131 256.0
HKD2_k127_6541201_14 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000007719 243.0
HKD2_k127_6541201_15 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
HKD2_k127_6541201_16 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
HKD2_k127_6541201_17 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000001261 192.0
HKD2_k127_6541201_18 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000005474 196.0
HKD2_k127_6541201_19 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000004744 188.0
HKD2_k127_6541201_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 377.0
HKD2_k127_6541201_20 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000001246 183.0
HKD2_k127_6541201_21 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000001246 172.0
HKD2_k127_6541201_22 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890,K04566,K06878 - 6.1.1.10,6.1.1.20,6.1.1.6 0.00000000000000000000000000000000000000001695 157.0
HKD2_k127_6541201_23 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000001702 156.0
HKD2_k127_6541201_24 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000002608 144.0
HKD2_k127_6541201_25 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000007945 154.0
HKD2_k127_6541201_26 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000009019 117.0
HKD2_k127_6541201_27 Pfam AhpC TSA family - - - 0.0000000000000000000002086 106.0
HKD2_k127_6541201_28 - - - - 0.00000000000000003797 91.0
HKD2_k127_6541201_29 Glycosyl transferase, family 2 - - - 0.0000000000000003774 90.0
HKD2_k127_6541201_3 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 340.0
HKD2_k127_6541201_30 - - - - 0.0000000002407 64.0
HKD2_k127_6541201_31 Pilus assembly protein PilW K02656 - - 0.000001752 59.0
HKD2_k127_6541201_32 Roadblock/LC7 domain - - - 0.00002192 53.0
HKD2_k127_6541201_33 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000105 50.0
HKD2_k127_6541201_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HKD2_k127_6541201_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 322.0
HKD2_k127_6541201_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 325.0
HKD2_k127_6541201_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 291.0
HKD2_k127_6541201_8 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001995 281.0
HKD2_k127_6541201_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009655 273.0
HKD2_k127_6552401_0 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 359.0
HKD2_k127_6552401_1 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000004274 112.0
HKD2_k127_6555434_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.65e-254 799.0
HKD2_k127_6555434_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 434.0
HKD2_k127_6555434_10 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000002045 186.0
HKD2_k127_6555434_11 Radical SAM superfamily - - - 0.0000000000000000000000000000000004158 149.0
HKD2_k127_6555434_12 von Willebrand factor, type A - - - 0.00000000000000000000000000000009746 142.0
HKD2_k127_6555434_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000001509 92.0
HKD2_k127_6555434_14 Glycosyl transferase, family 2 - - - 0.00000000000000000417 96.0
HKD2_k127_6555434_15 Glycosyl transferase K20444 - - 0.0000000000000001659 93.0
HKD2_k127_6555434_16 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000003812 72.0
HKD2_k127_6555434_17 unfolded protein binding K06142 - - 0.000000002797 70.0
HKD2_k127_6555434_18 PFAM peptidase - - - 0.0005376 53.0
HKD2_k127_6555434_19 domain, Protein - - - 0.0007088 53.0
HKD2_k127_6555434_2 PFAM glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 365.0
HKD2_k127_6555434_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 316.0
HKD2_k127_6555434_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003054 281.0
HKD2_k127_6555434_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
HKD2_k127_6555434_6 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002475 231.0
HKD2_k127_6555434_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000001721 209.0
HKD2_k127_6555434_8 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000008776 194.0
HKD2_k127_6555434_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000001663 183.0
HKD2_k127_6578478_0 Heat shock 70 kDa protein K04043 - - 6.175e-289 899.0
HKD2_k127_6578478_1 symporter activity K03307,K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 512.0
HKD2_k127_6578478_10 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000009861 182.0
HKD2_k127_6578478_11 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000000000000946 132.0
HKD2_k127_6578478_12 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000003531 131.0
HKD2_k127_6578478_13 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000003084 125.0
HKD2_k127_6578478_14 NUDIX domain K03574 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000008983 113.0
HKD2_k127_6578478_15 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000116 103.0
HKD2_k127_6578478_16 COG3209 Rhs family protein - - - 0.000000000000000001158 101.0
HKD2_k127_6578478_17 - - - - 0.000000000000000005508 91.0
HKD2_k127_6578478_18 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000007458 95.0
HKD2_k127_6578478_19 Tetratricopeptide repeat - - - 0.0000000000001034 85.0
HKD2_k127_6578478_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 467.0
HKD2_k127_6578478_20 Hsp20/alpha crystallin family K13993 - - 0.000000000000749 76.0
HKD2_k127_6578478_21 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000008491 72.0
HKD2_k127_6578478_22 Domain of unknown function (DUF1844) - - - 0.000005234 54.0
HKD2_k127_6578478_3 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 405.0
HKD2_k127_6578478_4 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001019 272.0
HKD2_k127_6578478_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
HKD2_k127_6578478_6 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000178 259.0
HKD2_k127_6578478_7 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000007353 247.0
HKD2_k127_6578478_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD2_k127_6578478_9 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000001984 195.0
HKD2_k127_6584523_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 545.0
HKD2_k127_6584523_1 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000001162 162.0
HKD2_k127_6584523_2 TIGRFAM methyltransferase FkbM - - - 0.0000000000000000000000000000000000000001775 164.0
HKD2_k127_6584523_3 pfam abc K09691 - - 0.000000000000000006902 90.0
HKD2_k127_658764_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 396.0
HKD2_k127_658764_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 370.0
HKD2_k127_658764_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000003173 157.0
HKD2_k127_658764_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000001502 114.0
HKD2_k127_658764_4 Protein of unknown function (DUF1109) - - - 0.00001905 55.0
HKD2_k127_6658040_0 butyrate kinase activity K00625,K00929,K04020,K13788 GO:0003674,GO:0003824,GO:0006950,GO:0008150,GO:0008959,GO:0009266,GO:0009408,GO:0009628,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0050896 2.3.1.8,2.7.2.7 3.522e-272 849.0
HKD2_k127_6658040_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000005632 213.0
HKD2_k127_6658040_2 Rubrerythrin - - - 0.000002066 54.0
HKD2_k127_6683418_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 392.0
HKD2_k127_6683418_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008829 244.0
HKD2_k127_6683418_2 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000008101 233.0
HKD2_k127_6683418_3 Peptidase family M28 K19702 - 3.4.11.24 0.00000000000001505 88.0
HKD2_k127_6683418_4 peptidyl-tyrosine sulfation - - - 0.00000000002843 76.0
HKD2_k127_6715103_0 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 325.0
HKD2_k127_6715103_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000005946 119.0
HKD2_k127_6720991_0 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 487.0
HKD2_k127_6720991_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
HKD2_k127_6720991_3 AMP-binding enzyme - - - 0.00000000000000000000000000000000007283 140.0
HKD2_k127_6720991_4 Tetratricopeptide repeat - - - 0.0000000000000000003859 97.0
HKD2_k127_6720991_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000001553 70.0
HKD2_k127_6753790_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 8.041e-251 803.0
HKD2_k127_6753790_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
HKD2_k127_6753790_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000634 58.0
HKD2_k127_6753790_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000001799 55.0
HKD2_k127_6753790_12 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00008004 54.0
HKD2_k127_6753790_2 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002371 292.0
HKD2_k127_6753790_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000005264 194.0
HKD2_k127_6753790_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000006701 184.0
HKD2_k127_6753790_5 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000005899 173.0
HKD2_k127_6753790_6 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000003258 167.0
HKD2_k127_6753790_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000002539 160.0
HKD2_k127_6753790_8 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000002625 155.0
HKD2_k127_6753790_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000002105 74.0
HKD2_k127_6792542_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 328.0
HKD2_k127_6792542_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 276.0
HKD2_k127_6792542_2 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
HKD2_k127_6792542_3 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000001645 223.0
HKD2_k127_6792542_4 Belongs to the pirin family K06911 - - 0.000000000000004425 74.0
HKD2_k127_6844443_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.513e-198 645.0
HKD2_k127_6844443_1 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 345.0
HKD2_k127_6844443_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000006222 175.0
HKD2_k127_6844443_3 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.00000745 54.0
HKD2_k127_6855391_0 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000001223 212.0
HKD2_k127_6855391_1 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000001695 213.0
HKD2_k127_6855391_2 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000005153 159.0
HKD2_k127_6855391_3 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000000000000000000000000000000002502 153.0
HKD2_k127_6855391_4 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000002915 132.0
HKD2_k127_6855391_5 methyltransferase activity - - - 0.000000000000000000007025 100.0
HKD2_k127_6855391_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000001322 93.0
HKD2_k127_6855391_7 Peptidase family M28 - - - 0.00000002198 61.0
HKD2_k127_6895540_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 486.0
HKD2_k127_6895540_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 478.0
HKD2_k127_6904459_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 461.0
HKD2_k127_6904459_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 373.0
HKD2_k127_6904459_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD2_k127_6904459_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000001971 160.0
HKD2_k127_6904459_4 Tetratricopeptide repeat - - - 0.0000000000000000000000003117 119.0
HKD2_k127_6904459_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000009913 61.0
HKD2_k127_6908533_0 Na H antiporter K03315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 401.0
HKD2_k127_6908533_1 Proton-conducting membrane transporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 381.0
HKD2_k127_6908533_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000001699 226.0
HKD2_k127_6908533_3 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000006365 169.0
HKD2_k127_6908533_4 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000002106 126.0
HKD2_k127_6960075_0 ABC transporter transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 494.0
HKD2_k127_6960075_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 459.0
HKD2_k127_6960075_10 domain, Protein - - - 0.00000000000000000000000000000000006006 154.0
HKD2_k127_6960075_11 Protein of unknown function, DUF547 - - - 0.00007066 54.0
HKD2_k127_6960075_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 442.0
HKD2_k127_6960075_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 394.0
HKD2_k127_6960075_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 353.0
HKD2_k127_6960075_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HKD2_k127_6960075_6 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009479 247.0
HKD2_k127_6960075_7 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000003858 234.0
HKD2_k127_6960075_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain - - - 0.000000000000000000000000000000000000000002556 160.0
HKD2_k127_6960075_9 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.000000000000000000000000000000000000000663 156.0
HKD2_k127_6962880_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 2.532e-219 709.0
HKD2_k127_6962880_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 6.74e-203 648.0
HKD2_k127_6962880_10 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000002063 216.0
HKD2_k127_6962880_11 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
HKD2_k127_6962880_12 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000001736 202.0
HKD2_k127_6962880_13 Pfam:TPM K08988 - - 0.000000000000000000000000000000000007609 156.0
HKD2_k127_6962880_14 chain release factor K15034 - - 0.000000000000000000000000000000002148 134.0
HKD2_k127_6962880_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000004084 147.0
HKD2_k127_6962880_16 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000001937 132.0
HKD2_k127_6962880_17 - - - - 0.00000000000000000000000000001974 120.0
HKD2_k127_6962880_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000001414 113.0
HKD2_k127_6962880_19 Transcriptional regulator - - - 0.0000000000000000000000008516 110.0
HKD2_k127_6962880_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 572.0
HKD2_k127_6962880_20 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000001433 118.0
HKD2_k127_6962880_21 family UPF0029 - - - 0.00000000000000000000002687 104.0
HKD2_k127_6962880_22 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000001413 101.0
HKD2_k127_6962880_23 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000006106 84.0
HKD2_k127_6962880_24 TIGRFAM TonB K03832 - - 0.00000000000000007644 91.0
HKD2_k127_6962880_25 - - - - 0.000000000000001583 89.0
HKD2_k127_6962880_26 photosystem II stabilization - - - 0.000000000000004718 89.0
HKD2_k127_6962880_28 acyl carrier protein - - - 0.000000001866 63.0
HKD2_k127_6962880_29 - - - - 0.00005183 54.0
HKD2_k127_6962880_3 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 535.0
HKD2_k127_6962880_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 519.0
HKD2_k127_6962880_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 449.0
HKD2_k127_6962880_6 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 314.0
HKD2_k127_6962880_7 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
HKD2_k127_6962880_8 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000002353 222.0
HKD2_k127_6962880_9 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000004072 209.0
HKD2_k127_6968145_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 328.0
HKD2_k127_6968145_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HKD2_k127_6968145_2 - - - - 0.00000000000000000000000000000000000002225 152.0
HKD2_k127_6968145_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000005462 127.0
HKD2_k127_6968145_4 Secretion protein K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.0000000000006351 81.0
HKD2_k127_6968145_5 DUF218 domain - - - 0.000000007245 63.0
HKD2_k127_7013984_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HKD2_k127_7013984_1 kinase activity K02850 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000000000000000000000000000000000000002025 194.0
HKD2_k127_7013984_2 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000002347 149.0
HKD2_k127_7024444_0 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004299 260.0
HKD2_k127_7024444_2 lyase activity - - - 0.0000003904 61.0
HKD2_k127_7086867_0 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002904 113.0
HKD2_k127_7086867_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000002961 74.0
HKD2_k127_7086867_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000001315 59.0
HKD2_k127_7086867_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000002392 52.0
HKD2_k127_7086867_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00002835 52.0
HKD2_k127_712803_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 301.0
HKD2_k127_712803_1 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000001038 259.0
HKD2_k127_712803_2 DinB family - - - 0.00000000000000000000000000000000000000000000002596 176.0
HKD2_k127_712803_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000002527 103.0
HKD2_k127_712803_4 protein conserved in bacteria K07028 - - 0.00000000000000000005793 91.0
HKD2_k127_712803_5 RESPONSE REGULATOR receiver - - - 0.00002678 52.0
HKD2_k127_7165579_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 449.0
HKD2_k127_717233_0 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003109 250.0
HKD2_k127_717233_1 - - - - 0.0000000000000006015 86.0
HKD2_k127_7223927_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
HKD2_k127_7223927_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 404.0
HKD2_k127_7223927_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000001415 247.0
HKD2_k127_7223927_3 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000148 73.0
HKD2_k127_7223927_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000003756 71.0
HKD2_k127_730120_0 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
HKD2_k127_730120_1 PFAM glycosyl transferase family 39 K14340 - - 0.000000000000000000000000000000000000002668 166.0
HKD2_k127_730120_2 DAK2 domain fusion protein YloV K07030 - - 0.00000000008397 64.0
HKD2_k127_730120_3 Psort location CytoplasmicMembrane, score - - - 0.0002812 53.0
HKD2_k127_7456_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1070.0
HKD2_k127_7456_1 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 5.371e-201 635.0
HKD2_k127_7456_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 316.0
HKD2_k127_7456_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
HKD2_k127_7456_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001316 121.0
HKD2_k127_7456_5 peptidase U32 - - - 0.00000000000000000001644 95.0
HKD2_k127_7456_6 - - - - 0.0000000000000007709 90.0
HKD2_k127_7686813_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 441.0
HKD2_k127_7686813_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 441.0
HKD2_k127_7686813_10 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000001803 191.0
HKD2_k127_7686813_11 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000009326 154.0
HKD2_k127_7686813_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000339 139.0
HKD2_k127_7686813_13 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000002692 120.0
HKD2_k127_7686813_14 PFAM phosphoryl transfer system HPr K11189 - - 0.000000000000000000000008473 103.0
HKD2_k127_7686813_15 - - - - 0.00000000000000000000001902 113.0
HKD2_k127_7686813_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000006122 100.0
HKD2_k127_7686813_17 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000007929 92.0
HKD2_k127_7686813_18 - - - - 0.000000000000001215 86.0
HKD2_k127_7686813_19 Mannose-6-phosphate isomerase - - - 0.00000000000003985 79.0
HKD2_k127_7686813_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 372.0
HKD2_k127_7686813_20 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000284 78.0
HKD2_k127_7686813_21 Putative zinc- or iron-chelating domain - - - 0.000000000003539 69.0
HKD2_k127_7686813_22 Domain of unknown function (DUF4115) K15539 - - 0.0000000002104 71.0
HKD2_k127_7686813_23 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0003671 54.0
HKD2_k127_7686813_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 350.0
HKD2_k127_7686813_4 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 323.0
HKD2_k127_7686813_5 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 306.0
HKD2_k127_7686813_6 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000008389 247.0
HKD2_k127_7686813_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000001384 225.0
HKD2_k127_7686813_8 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000001579 215.0
HKD2_k127_7686813_9 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000004968 197.0
HKD2_k127_7687626_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 505.0
HKD2_k127_7687626_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 334.0
HKD2_k127_7688142_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.345e-247 773.0
HKD2_k127_7688142_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 533.0
HKD2_k127_7688142_10 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000001695 175.0
HKD2_k127_7688142_11 Cytochrome oxidase assembly protein K02259,K03110 - - 0.000000000000000000000000000000000000001584 166.0
HKD2_k127_7688142_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000226 146.0
HKD2_k127_7688142_13 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000004726 117.0
HKD2_k127_7688142_14 Alg9-like mannosyltransferase family K05286 - - 0.00000000000000000239 98.0
HKD2_k127_7688142_15 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000009633 89.0
HKD2_k127_7688142_16 MarR family - - - 0.00002835 52.0
HKD2_k127_7688142_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 467.0
HKD2_k127_7688142_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 469.0
HKD2_k127_7688142_4 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 362.0
HKD2_k127_7688142_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 316.0
HKD2_k127_7688142_6 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004573 304.0
HKD2_k127_7688142_7 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
HKD2_k127_7688142_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000006126 224.0
HKD2_k127_7688142_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000001057 225.0
HKD2_k127_7701449_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 304.0
HKD2_k127_7701449_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000004037 191.0
HKD2_k127_7701449_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000003451 169.0
HKD2_k127_7701449_3 PQQ-like domain - - - 0.0000000000003019 80.0
HKD2_k127_7701449_4 PQQ enzyme repeat - - - 0.00000000000115 73.0
HKD2_k127_7701449_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000001389 75.0
HKD2_k127_7703061_0 Glycosyltransferase like family 2 - - - 7.31e-198 642.0
HKD2_k127_7703061_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HKD2_k127_7703061_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
HKD2_k127_7703061_3 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005833 294.0
HKD2_k127_7703061_4 ABC transporter, permease protein K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004233 258.0
HKD2_k127_7703061_5 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000001324 245.0
HKD2_k127_7703061_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002922 247.0
HKD2_k127_7703061_7 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000009319 129.0
HKD2_k127_7703061_8 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000001073 130.0
HKD2_k127_7703061_9 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000008374 91.0
HKD2_k127_7704298_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.89e-232 745.0
HKD2_k127_7704298_1 PFAM Type II secretion system protein E K02652 - - 1.362e-213 677.0
HKD2_k127_7704298_10 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000006335 207.0
HKD2_k127_7704298_11 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000001451 193.0
HKD2_k127_7704298_12 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000007736 190.0
HKD2_k127_7704298_13 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000001546 177.0
HKD2_k127_7704298_14 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000003667 127.0
HKD2_k127_7704298_15 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000001664 127.0
HKD2_k127_7704298_16 - - - - 0.00000000000000000003632 94.0
HKD2_k127_7704298_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000236 83.0
HKD2_k127_7704298_18 general secretion pathway protein K02456,K02650 - - 0.000000000000001665 86.0
HKD2_k127_7704298_19 Pilus assembly protein K02662 - - 0.00000001079 67.0
HKD2_k127_7704298_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 562.0
HKD2_k127_7704298_20 PFAM Fimbrial assembly family protein K02663 - - 0.0000002301 61.0
HKD2_k127_7704298_3 glycosyl hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 555.0
HKD2_k127_7704298_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 362.0
HKD2_k127_7704298_5 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 328.0
HKD2_k127_7704298_6 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 301.0
HKD2_k127_7704298_7 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000129 298.0
HKD2_k127_7704298_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001306 268.0
HKD2_k127_7704298_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
HKD2_k127_7709050_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
HKD2_k127_7709050_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000007383 161.0
HKD2_k127_7709050_2 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000005334 115.0
HKD2_k127_7709050_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000004278 98.0
HKD2_k127_7709050_4 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000000000008793 102.0
HKD2_k127_7709050_5 glycoprotease K14742 - - 0.0000000000003113 79.0
HKD2_k127_7709050_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000006771 73.0
HKD2_k127_7709050_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000844 64.0
HKD2_k127_7714240_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000002884 149.0
HKD2_k127_7714240_1 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000003198 57.0
HKD2_k127_7724234_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.856e-282 884.0
HKD2_k127_7724234_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.432e-199 627.0
HKD2_k127_7724234_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
HKD2_k127_7724234_11 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 339.0
HKD2_k127_7724234_12 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 328.0
HKD2_k127_7724234_13 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 335.0
HKD2_k127_7724234_14 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 330.0
HKD2_k127_7724234_15 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002887 287.0
HKD2_k127_7724234_16 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007706 289.0
HKD2_k127_7724234_17 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 271.0
HKD2_k127_7724234_18 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000001956 264.0
HKD2_k127_7724234_19 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002735 239.0
HKD2_k127_7724234_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 612.0
HKD2_k127_7724234_20 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000001258 229.0
HKD2_k127_7724234_21 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000003535 182.0
HKD2_k127_7724234_22 Signal peptidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000002496 167.0
HKD2_k127_7724234_23 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000004617 164.0
HKD2_k127_7724234_24 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000004944 165.0
HKD2_k127_7724234_25 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000002794 147.0
HKD2_k127_7724234_26 amidohydrolase - - - 0.000000000000000000000000000000000001788 158.0
HKD2_k127_7724234_27 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000002417 151.0
HKD2_k127_7724234_28 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000001897 148.0
HKD2_k127_7724234_29 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000001265 139.0
HKD2_k127_7724234_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 540.0
HKD2_k127_7724234_30 FMN binding - - - 0.0000000000000000000000000000818 122.0
HKD2_k127_7724234_31 Hfq protein - - - 0.000000000000000000000000007205 116.0
HKD2_k127_7724234_32 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000001211 106.0
HKD2_k127_7724234_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004699 70.0
HKD2_k127_7724234_35 Methionine biosynthesis protein MetW - - - 0.000001348 59.0
HKD2_k127_7724234_36 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000857 59.0
HKD2_k127_7724234_37 Transcriptional regulator - - - 0.00005315 55.0
HKD2_k127_7724234_4 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 458.0
HKD2_k127_7724234_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 452.0
HKD2_k127_7724234_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 434.0
HKD2_k127_7724234_7 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 421.0
HKD2_k127_7724234_8 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 406.0
HKD2_k127_7724234_9 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
HKD2_k127_7780096_0 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 398.0
HKD2_k127_7780096_1 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 382.0
HKD2_k127_7780096_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 355.0
HKD2_k127_7780096_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001415 196.0
HKD2_k127_7780715_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.844e-293 929.0
HKD2_k127_7780715_1 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 506.0
HKD2_k127_7780715_10 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001213 227.0
HKD2_k127_7780715_11 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000006406 205.0
HKD2_k127_7780715_12 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000002289 196.0
HKD2_k127_7780715_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000001476 176.0
HKD2_k127_7780715_14 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000005932 175.0
HKD2_k127_7780715_15 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000008639 158.0
HKD2_k127_7780715_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000003201 124.0
HKD2_k127_7780715_17 cheY-homologous receiver domain - - - 0.000000000000000000000284 102.0
HKD2_k127_7780715_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000002296 93.0
HKD2_k127_7780715_19 overlaps another CDS with the same product name K16091 - - 0.0000000000000000009413 100.0
HKD2_k127_7780715_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 495.0
HKD2_k127_7780715_20 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000009337 94.0
HKD2_k127_7780715_22 SH3 type 3 domain protein K01447 - 3.5.1.28 0.000000000839 68.0
HKD2_k127_7780715_3 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 469.0
HKD2_k127_7780715_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 410.0
HKD2_k127_7780715_5 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 389.0
HKD2_k127_7780715_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 301.0
HKD2_k127_7780715_7 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 294.0
HKD2_k127_7780715_8 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
HKD2_k127_7780715_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HKD2_k127_7799733_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1762.0
HKD2_k127_7799733_1 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 614.0
HKD2_k127_7799733_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 331.0
HKD2_k127_7799733_11 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 292.0
HKD2_k127_7799733_12 COGs COG0790 FOG TPR repeat SEL1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HKD2_k127_7799733_13 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000002962 160.0
HKD2_k127_7799733_14 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000003472 143.0
HKD2_k127_7799733_15 - - - - 0.0000000000000000000000000000001662 133.0
HKD2_k127_7799733_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000001791 120.0
HKD2_k127_7799733_17 Belongs to the 'phage' integrase family - - - 0.00006612 46.0
HKD2_k127_7799733_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 591.0
HKD2_k127_7799733_3 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 507.0
HKD2_k127_7799733_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 430.0
HKD2_k127_7799733_5 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 451.0
HKD2_k127_7799733_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 402.0
HKD2_k127_7799733_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 405.0
HKD2_k127_7799733_8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 385.0
HKD2_k127_7799733_9 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 337.0
HKD2_k127_7809403_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 473.0
HKD2_k127_7820188_0 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000001083 112.0
HKD2_k127_7820188_1 Helix-hairpin-helix motif K02237 - - 0.00000000000000002815 83.0
HKD2_k127_7832796_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000009215 172.0
HKD2_k127_7832796_1 CGNR zinc finger - - - 0.0000000000000000000000000000000000003256 147.0
HKD2_k127_7846189_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 550.0
HKD2_k127_7851649_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 331.0
HKD2_k127_7851649_1 Carboxypeptidase regulatory-like domain - - - 0.0000008334 55.0
HKD2_k127_7881308_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.186e-285 893.0
HKD2_k127_7881308_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 389.0
HKD2_k127_7881308_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
HKD2_k127_7881308_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003978 232.0
HKD2_k127_7881308_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000006914 185.0
HKD2_k127_7881308_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000849 128.0
HKD2_k127_7881308_6 - - - - 0.0000000000003049 72.0
HKD2_k127_7881308_7 Putative regulatory protein - - - 0.0000001856 60.0
HKD2_k127_7883503_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 391.0
HKD2_k127_7883503_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000002767 188.0
HKD2_k127_7883503_2 ABC-type multidrug transport system ATPase component K01990,K09695 - - 0.00000000000000000000000000000000000000000000001876 190.0
HKD2_k127_7883503_3 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000000004804 100.0
HKD2_k127_7883503_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000654 86.0
HKD2_k127_7916031_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.453e-225 709.0
HKD2_k127_7916031_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
HKD2_k127_7916031_10 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000002716 149.0
HKD2_k127_7916031_11 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000299 70.0
HKD2_k127_7916031_12 TonB-dependent siderophore receptor K02014 - - 0.00008661 46.0
HKD2_k127_7916031_2 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 434.0
HKD2_k127_7916031_3 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 365.0
HKD2_k127_7916031_4 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001198 237.0
HKD2_k127_7916031_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
HKD2_k127_7916031_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000001319 210.0
HKD2_k127_7916031_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000006345 210.0
HKD2_k127_7916031_8 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000107 169.0
HKD2_k127_7916031_9 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000001111 168.0
HKD2_k127_7934311_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 481.0
HKD2_k127_7934311_1 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
HKD2_k127_7934311_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000002536 179.0
HKD2_k127_7934311_3 Putative adhesin - - - 0.000000000000000000000000001283 121.0
HKD2_k127_7934311_4 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000001076 109.0
HKD2_k127_7934311_5 Domain of unknown function (DUF4349) - - - 0.000002529 59.0
HKD2_k127_7949234_0 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000000001609 183.0
HKD2_k127_7949234_1 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000002835 165.0
HKD2_k127_7949234_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000002514 117.0
HKD2_k127_7957823_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 321.0
HKD2_k127_7957823_1 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000378 169.0
HKD2_k127_7957823_2 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000003396 142.0
HKD2_k127_7973978_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
HKD2_k127_7973978_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000006722 222.0
HKD2_k127_7973978_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.000000000000000000000000000000000002393 154.0
HKD2_k127_7973978_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000001606 121.0
HKD2_k127_7973978_4 ATPase or kinase K06925 - - 0.0000000000000000008953 100.0
HKD2_k127_8013945_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 348.0
HKD2_k127_8013945_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001078 268.0
HKD2_k127_8046079_0 Porin subfamily - - - 0.000000000000000000000000000000000000000000000001648 188.0
HKD2_k127_8061939_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.679e-276 872.0
HKD2_k127_8061939_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.686e-271 856.0
HKD2_k127_8061939_10 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
HKD2_k127_8061939_11 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000006471 221.0
HKD2_k127_8061939_12 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000001573 200.0
HKD2_k127_8061939_13 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000006269 192.0
HKD2_k127_8061939_14 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000002644 179.0
HKD2_k127_8061939_15 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000002176 187.0
HKD2_k127_8061939_16 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000001783 151.0
HKD2_k127_8061939_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000009691 150.0
HKD2_k127_8061939_18 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000626 139.0
HKD2_k127_8061939_19 Lipoate-protein ligase - - - 0.0000000000000000000000000006268 127.0
HKD2_k127_8061939_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 416.0
HKD2_k127_8061939_20 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001857 113.0
HKD2_k127_8061939_21 Sporulation and spore germination - - - 0.0000000000000007425 87.0
HKD2_k127_8061939_22 Polymer-forming cytoskeletal - - - 0.00000000000003336 81.0
HKD2_k127_8061939_23 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000431 72.0
HKD2_k127_8061939_24 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000001002 79.0
HKD2_k127_8061939_25 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000004234 68.0
HKD2_k127_8061939_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 379.0
HKD2_k127_8061939_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
HKD2_k127_8061939_5 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
HKD2_k127_8061939_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004399 273.0
HKD2_k127_8061939_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000004653 268.0
HKD2_k127_8061939_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005406 269.0
HKD2_k127_8061939_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000005768 259.0
HKD2_k127_8086758_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 514.0
HKD2_k127_8086758_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 344.0
HKD2_k127_8086758_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001253 280.0
HKD2_k127_8086758_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000849 224.0
HKD2_k127_8086758_4 Zn peptidase - - - 0.000000000000000000000003773 115.0
HKD2_k127_8103157_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000001322 166.0
HKD2_k127_8103157_1 cheY-homologous receiver domain - - - 0.000000000004607 72.0
HKD2_k127_8103157_2 Diguanylate cyclase, GGDEF domain - - - 0.0000000000371 69.0
HKD2_k127_8103157_3 oxidation-reduction process - - - 0.000000382 52.0
HKD2_k127_8112442_0 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 390.0
HKD2_k127_8112442_1 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000001678 109.0
HKD2_k127_8115805_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 2.318e-194 632.0
HKD2_k127_8115805_1 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 558.0
HKD2_k127_8115805_10 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000002983 243.0
HKD2_k127_8115805_11 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000609 184.0
HKD2_k127_8115805_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000004238 173.0
HKD2_k127_8115805_13 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001075 159.0
HKD2_k127_8115805_14 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000002136 164.0
HKD2_k127_8115805_15 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000006649 165.0
HKD2_k127_8115805_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000001053 155.0
HKD2_k127_8115805_17 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000005596 151.0
HKD2_k127_8115805_18 - K01992 - - 0.0000000000000000000000000006129 128.0
HKD2_k127_8115805_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000002765 116.0
HKD2_k127_8115805_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 542.0
HKD2_k127_8115805_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000061 96.0
HKD2_k127_8115805_21 - - - - 0.0000003161 54.0
HKD2_k127_8115805_22 Domain of unknown function (DUF4440) - - - 0.0000008077 60.0
HKD2_k127_8115805_23 - - - - 0.0001034 53.0
HKD2_k127_8115805_3 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 503.0
HKD2_k127_8115805_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 447.0
HKD2_k127_8115805_5 Amino-transferase class IV K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
HKD2_k127_8115805_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007729 292.0
HKD2_k127_8115805_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003457 269.0
HKD2_k127_8115805_8 Competence-damaged protein K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000007419 265.0
HKD2_k127_8115805_9 Protein export membrane protein K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001296 269.0
HKD2_k127_8118050_0 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001112 236.0
HKD2_k127_8118050_1 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001309 196.0
HKD2_k127_8118050_2 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000003359 199.0
HKD2_k127_8118050_3 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000004754 159.0
HKD2_k127_8118050_4 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000009934 138.0
HKD2_k127_8118050_5 - - - - 0.0000000000000000000000000000002141 128.0
HKD2_k127_8118050_6 Phospholipid methyltransferase - - - 0.0002103 45.0
HKD2_k127_8133771_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 404.0
HKD2_k127_8133771_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000001678 99.0
HKD2_k127_8133771_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000004294 96.0
HKD2_k127_8154484_0 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 496.0
HKD2_k127_8154484_1 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 368.0
HKD2_k127_8154484_2 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
HKD2_k127_8154484_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000003369 226.0
HKD2_k127_8154484_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001731 182.0
HKD2_k127_8154484_5 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000001448 95.0
HKD2_k127_8158714_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 447.0
HKD2_k127_8158714_1 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 399.0
HKD2_k127_8158714_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000003086 190.0
HKD2_k127_8158714_3 - - - - 0.000000000000000000417 91.0
HKD2_k127_8158714_4 oxidoreductase activity - - - 0.0000001452 64.0
HKD2_k127_8165492_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 453.0
HKD2_k127_8165492_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 376.0
HKD2_k127_8165492_2 - - - - 0.000000000000000000000000000000000009976 147.0
HKD2_k127_8165492_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000002532 91.0
HKD2_k127_8165492_4 Oligopeptidase F K08602 - - 0.00001661 47.0
HKD2_k127_8182946_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 392.0
HKD2_k127_8182946_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001798 261.0
HKD2_k127_8182946_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000007058 180.0
HKD2_k127_8182946_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000001407 160.0
HKD2_k127_8182946_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001448 155.0
HKD2_k127_8182946_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000006662 139.0
HKD2_k127_8182946_6 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000668 131.0
HKD2_k127_8182946_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003889 99.0
HKD2_k127_8182946_8 Could be involved in septation K06412 - - 0.000000000000000000006683 96.0
HKD2_k127_8182946_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000007134 85.0
HKD2_k127_8232028_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1587.0
HKD2_k127_8232028_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 605.0
HKD2_k127_8232028_2 HlyD membrane-fusion protein of T1SS K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 461.0
HKD2_k127_8232028_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000005502 68.0
HKD2_k127_8234748_0 Zinc-binding dehydrogenase K22231 - - 4.244e-200 630.0
HKD2_k127_8234748_1 ATPases associated with a variety of cellular activities K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 484.0
HKD2_k127_8234748_2 Belongs to the binding-protein-dependent transport system permease family K10439,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 423.0
HKD2_k127_8234748_3 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 334.0
HKD2_k127_8234748_4 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000000000000000000000000000000000000001517 192.0
HKD2_k127_8264873_0 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
HKD2_k127_8264873_1 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 301.0
HKD2_k127_8264873_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000002345 83.0
HKD2_k127_8282882_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1038.0
HKD2_k127_8282882_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.87e-205 649.0
HKD2_k127_8282882_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 430.0
HKD2_k127_8282882_3 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 326.0
HKD2_k127_8282882_4 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 313.0
HKD2_k127_8282882_5 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000002284 203.0
HKD2_k127_8282882_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.0000000000000000000000000000000002028 141.0
HKD2_k127_8282882_7 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000005187 129.0
HKD2_k127_8282882_8 DinB family - - - 0.000000000000000000000001627 109.0
HKD2_k127_8331987_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000005491 190.0
HKD2_k127_8331987_1 TonB-dependent Receptor Plug K02014,K16089 - - 0.000008095 54.0
HKD2_k127_8390001_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 356.0
HKD2_k127_8390001_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000003668 241.0
HKD2_k127_8390001_2 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000002118 196.0
HKD2_k127_8390001_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000004204 117.0
HKD2_k127_8533400_0 acetyltransferase - - - 0.00000000000000000000000000000000000006858 156.0
HKD2_k127_8533400_1 TIGRFAM hemolysin TlyA family protein K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.0000000000000000000000000006116 115.0
HKD2_k127_8533400_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000005025 81.0
HKD2_k127_8533400_3 membrane - - - 0.0008481 45.0
HKD2_k127_8649320_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005825 259.0
HKD2_k127_8649320_1 Inositol monophosphatase K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000002741 86.0
HKD2_k127_8649320_2 - - - - 0.0000000001394 66.0
HKD2_k127_889029_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 338.0
HKD2_k127_893475_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 465.0
HKD2_k127_893475_1 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000579 203.0
HKD2_k127_893475_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000007337 159.0
HKD2_k127_893475_3 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.000000000000000005864 98.0
HKD2_k127_8958853_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000003208 254.0
HKD2_k127_8958853_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000001942 56.0
HKD2_k127_8958853_2 - - - - 0.000007896 51.0
HKD2_k127_8970309_0 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008292 266.0
HKD2_k127_8970309_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
HKD2_k127_8970309_2 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000001545 162.0
HKD2_k127_8970309_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000005205 117.0
HKD2_k127_8970309_4 AAA domain K01939 - 6.3.4.4 0.000000000004291 77.0
HKD2_k127_8970309_5 Chloramphenicol phosphotransferase-like protein - - - 0.00000000007473 69.0
HKD2_k127_8970309_6 SNARE associated Golgi protein - - - 0.0000001626 53.0
HKD2_k127_8970309_7 NTPase K06928 - 3.6.1.15 0.000006251 51.0
HKD2_k127_897259_0 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HKD2_k127_897259_1 Transposase - - - 0.0000000000000000000000000000000000000000000000005947 193.0
HKD2_k127_897259_2 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000002247 133.0
HKD2_k127_897259_3 PFAM Transposase IS66 family - - - 0.000000000000000000000000000002153 123.0
HKD2_k127_8984458_0 Tricorn protease homolog - - - 0.0 1433.0
HKD2_k127_8984458_1 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 545.0
HKD2_k127_8984458_2 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 444.0
HKD2_k127_8984458_3 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
HKD2_k127_8984458_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 340.0
HKD2_k127_8984458_5 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
HKD2_k127_8984458_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000001217 168.0
HKD2_k127_8984458_7 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000004099 166.0
HKD2_k127_8984458_8 response regulator K13599 - - 0.000000000000000000000000000000018 129.0
HKD2_k127_8984458_9 4Fe-4S binding domain - - - 0.000000000005559 77.0
HKD2_k127_9026381_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1180.0
HKD2_k127_9026381_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 552.0
HKD2_k127_9026381_10 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000001014 72.0
HKD2_k127_9026381_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 308.0
HKD2_k127_9026381_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000004627 217.0
HKD2_k127_9026381_4 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000001141 172.0
HKD2_k127_9026381_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000001205 180.0
HKD2_k127_9026381_6 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000001406 149.0
HKD2_k127_9026381_7 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000003251 134.0
HKD2_k127_9026381_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001465 89.0
HKD2_k127_9026381_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000008435 87.0
HKD2_k127_9052140_0 Sugar phosphate permease K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 585.0
HKD2_k127_9052140_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 337.0
HKD2_k127_9056533_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 5.439e-206 655.0
HKD2_k127_9056533_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 526.0
HKD2_k127_9056533_10 General transcription factor 3C polypeptide K15201 - - 0.0002769 49.0
HKD2_k127_9056533_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 493.0
HKD2_k127_9056533_3 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 373.0
HKD2_k127_9056533_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 326.0
HKD2_k127_9056533_5 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 308.0
HKD2_k127_9056533_6 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001153 291.0
HKD2_k127_9056533_7 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001147 200.0
HKD2_k127_9056533_8 transcription factor binding - - - 0.000000000000000000000000000007891 124.0
HKD2_k127_9056533_9 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.000000000001094 68.0
HKD2_k127_9070089_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HKD2_k127_9070089_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 277.0
HKD2_k127_9070089_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000105 253.0
HKD2_k127_9100331_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000001236 261.0
HKD2_k127_9100331_1 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000005091 136.0
HKD2_k127_9100331_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000002026 125.0
HKD2_k127_9100331_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000002432 133.0
HKD2_k127_9100331_4 general secretion pathway protein K08084,K08085 - - 0.000001945 55.0
HKD2_k127_9145877_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 4.602e-219 693.0
HKD2_k127_9145877_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000002255 181.0
HKD2_k127_9147641_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 3.013e-218 701.0
HKD2_k127_9147641_1 B12 binding domain - - - 1.074e-203 645.0
HKD2_k127_9147641_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000007613 191.0
HKD2_k127_9147641_11 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000002141 141.0
HKD2_k127_9147641_12 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000008768 100.0
HKD2_k127_9147641_13 Rubrerythrin - - - 0.0009897 48.0
HKD2_k127_9147641_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 436.0
HKD2_k127_9147641_3 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 425.0
HKD2_k127_9147641_4 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 407.0
HKD2_k127_9147641_5 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 333.0
HKD2_k127_9147641_6 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
HKD2_k127_9147641_7 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 316.0
HKD2_k127_9147641_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
HKD2_k127_9147641_9 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000001441 228.0
HKD2_k127_9161398_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 334.0
HKD2_k127_9161398_1 Bacterial regulatory proteins, tetR family - - - 0.0000002203 60.0
HKD2_k127_9161398_2 Psort location Cytoplasmic, score - - - 0.00009078 55.0
HKD2_k127_9161929_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 1.13e-234 739.0
HKD2_k127_9161929_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.127e-225 720.0
HKD2_k127_9161929_10 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000006013 230.0
HKD2_k127_9161929_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000002533 218.0
HKD2_k127_9161929_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000002069 154.0
HKD2_k127_9161929_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001633 128.0
HKD2_k127_9161929_14 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000303 133.0
HKD2_k127_9161929_15 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000004164 121.0
HKD2_k127_9161929_16 Transcriptional regulator K03710,K07978,K07979 - - 0.0000000000000000000000002073 111.0
HKD2_k127_9161929_17 Ribosome-binding factor A - - - 0.00000000000000002964 89.0
HKD2_k127_9161929_18 succinate dehydrogenase activity K00242,K00246 - - 0.0000000000006978 73.0
HKD2_k127_9161929_19 Protein conserved in bacteria K09764 - - 0.0000000006086 64.0
HKD2_k127_9161929_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.868e-198 647.0
HKD2_k127_9161929_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
HKD2_k127_9161929_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 374.0
HKD2_k127_9161929_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000311 278.0
HKD2_k127_9161929_6 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD2_k127_9161929_7 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
HKD2_k127_9161929_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD2_k127_9161929_9 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000003455 239.0
HKD2_k127_9172821_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 463.0
HKD2_k127_9172821_1 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 426.0
HKD2_k127_9172821_2 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 370.0
HKD2_k127_9172821_3 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HKD2_k127_9172821_4 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000247 205.0
HKD2_k127_9172821_5 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000003843 96.0
HKD2_k127_9173946_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 3.561e-210 659.0
HKD2_k127_9173946_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 336.0
HKD2_k127_9173946_10 COGs COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00001864 57.0
HKD2_k127_9173946_2 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000001522 160.0
HKD2_k127_9173946_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000009736 116.0
HKD2_k127_9173946_4 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000004202 101.0
HKD2_k127_9173946_5 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000273 85.0
HKD2_k127_9173946_6 translation initiation factor activity K12065,K13671 - - 0.00000000000008827 83.0
HKD2_k127_9173946_7 PFAM glycosyl transferase group 1 - - - 0.000000000005233 78.0
HKD2_k127_9173946_8 - - - - 0.0000000006483 72.0
HKD2_k127_9173946_9 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000005843 59.0
HKD2_k127_9175492_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 566.0
HKD2_k127_9175492_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 458.0
HKD2_k127_9175492_10 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 363.0
HKD2_k127_9175492_11 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 362.0
HKD2_k127_9175492_12 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HKD2_k127_9175492_13 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 336.0
HKD2_k127_9175492_14 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 350.0
HKD2_k127_9175492_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 333.0
HKD2_k127_9175492_16 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 327.0
HKD2_k127_9175492_17 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 319.0
HKD2_k127_9175492_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
HKD2_k127_9175492_19 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
HKD2_k127_9175492_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 464.0
HKD2_k127_9175492_20 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001861 282.0
HKD2_k127_9175492_21 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 253.0
HKD2_k127_9175492_22 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HKD2_k127_9175492_23 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000004868 233.0
HKD2_k127_9175492_24 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000006558 224.0
HKD2_k127_9175492_25 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000000000000000000003539 216.0
HKD2_k127_9175492_26 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000002661 207.0
HKD2_k127_9175492_27 GAF domain - - - 0.00000000000000000000000000000000000000000000000004586 192.0
HKD2_k127_9175492_28 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000003034 181.0
HKD2_k127_9175492_29 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000002859 163.0
HKD2_k127_9175492_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 439.0
HKD2_k127_9175492_30 protein kinase activity - - - 0.00000000000000000000000000000000000259 158.0
HKD2_k127_9175492_31 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000001688 144.0
HKD2_k127_9175492_33 - - - - 0.000000000000000000000000003706 121.0
HKD2_k127_9175492_34 Belongs to the MraZ family K03925 - - 0.000000000000000000000000004256 118.0
HKD2_k127_9175492_35 YMGG-like Gly-zipper - - - 0.000000000000000000000000006119 119.0
HKD2_k127_9175492_36 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000001939 125.0
HKD2_k127_9175492_39 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000005614 98.0
HKD2_k127_9175492_4 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 436.0
HKD2_k127_9175492_40 BatB protein K07114 - - 0.000000000000006296 89.0
HKD2_k127_9175492_41 Pfam Uncharacterised protein family UPF0047 - - - 0.00000000000002518 75.0
HKD2_k127_9175492_42 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000004522 79.0
HKD2_k127_9175492_43 - - - - 0.000000002263 64.0
HKD2_k127_9175492_44 Essential cell division protein K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000007413 63.0
HKD2_k127_9175492_45 - - - - 0.0000006251 57.0
HKD2_k127_9175492_47 Oxygen tolerance - - - 0.000002559 60.0
HKD2_k127_9175492_48 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000005014 58.0
HKD2_k127_9175492_49 Multicopper oxidase - - - 0.00007199 55.0
HKD2_k127_9175492_5 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 428.0
HKD2_k127_9175492_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 421.0
HKD2_k127_9175492_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 395.0
HKD2_k127_9175492_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 386.0
HKD2_k127_9175492_9 PFAM HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 363.0
HKD2_k127_9181310_0 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 545.0
HKD2_k127_9181310_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
HKD2_k127_9181310_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000003357 123.0
HKD2_k127_9181310_3 lyase activity - - - 0.000000000000000000000563 112.0
HKD2_k127_9181310_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000008406 84.0
HKD2_k127_9187029_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 443.0
HKD2_k127_9187029_1 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 322.0
HKD2_k127_9187029_2 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006565 254.0
HKD2_k127_9187029_3 - - - - 0.00001595 57.0
HKD2_k127_918841_0 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 331.0
HKD2_k127_918841_1 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 324.0
HKD2_k127_918841_2 Serine threonine protein kinase K07282,K12132,K15539 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003387 235.0
HKD2_k127_918841_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000003729 155.0
HKD2_k127_9189293_0 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003146 239.0
HKD2_k127_9189293_1 Periplasmic or secreted lipoprotein - - - 0.00000000000000006725 89.0
HKD2_k127_9189293_2 COG2407 L-fucose isomerase and related - - - 0.0000001271 55.0
HKD2_k127_9196941_0 Stress-induced protein - - - 0.0000000000000000000000000000000000000005744 162.0
HKD2_k127_9196941_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000006956 76.0
HKD2_k127_9196941_2 Protein of unknown function (DUF2723) - - - 0.0000000001866 73.0
HKD2_k127_9199828_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 9.487e-254 809.0
HKD2_k127_9199828_1 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 417.0
HKD2_k127_9199828_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 334.0
HKD2_k127_9199828_3 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 323.0
HKD2_k127_9199828_4 hydrolase of the alpha beta superfamily K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007636 273.0
HKD2_k127_9199828_5 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000005857 219.0
HKD2_k127_9199828_6 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000543 207.0
HKD2_k127_9199828_7 Major Facilitator Superfamily - - - 0.000000000000000000003801 106.0
HKD2_k127_9199828_8 Protein conserved in bacteria - - - 0.00000000000000002307 91.0
HKD2_k127_9208319_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 8.2e-268 852.0
HKD2_k127_9208319_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 601.0
HKD2_k127_9208319_10 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002763 254.0
HKD2_k127_9208319_11 PDGLE domain K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000001741 243.0
HKD2_k127_9208319_12 - - - - 0.00000000000000000000000000000000000000000000000000000000186 221.0
HKD2_k127_9208319_13 YhhN family - - - 0.00000000000000000000000000002961 135.0
HKD2_k127_9208319_14 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.0000000000000000000000002253 109.0
HKD2_k127_9208319_15 Cobalt ABC transporter K02008 - - 0.000000000000000000000002242 110.0
HKD2_k127_9208319_16 von Willebrand factor (vWF) type A domain K07114 - - 0.00000004452 57.0
HKD2_k127_9208319_17 long-chain fatty acid transporting porin activity K06076 - - 0.0001753 53.0
HKD2_k127_9208319_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 594.0
HKD2_k127_9208319_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 442.0
HKD2_k127_9208319_4 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 416.0
HKD2_k127_9208319_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 401.0
HKD2_k127_9208319_6 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 328.0
HKD2_k127_9208319_7 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 321.0
HKD2_k127_9208319_8 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001789 269.0
HKD2_k127_9208319_9 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000006286 258.0
HKD2_k127_9217279_0 Carbon starvation protein K06200 - - 1.573e-215 686.0
HKD2_k127_9217279_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 514.0
HKD2_k127_9217279_2 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 429.0
HKD2_k127_9217279_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 304.0
HKD2_k127_9217279_4 oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000002 151.0
HKD2_k127_9217279_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000004591 95.0
HKD2_k127_9217279_6 TPR repeat-containing protein - - - 0.00000001275 62.0
HKD2_k127_9225638_0 PFAM Aldehyde dehydrogenase K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 1.488e-237 745.0
HKD2_k127_9225638_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.166e-202 648.0
HKD2_k127_9225638_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000002117 116.0
HKD2_k127_9225638_11 Outer membrane efflux protein K12340 - - 0.0000000000006243 78.0
HKD2_k127_9225638_12 membrane protein domain - - - 0.000000000002148 79.0
HKD2_k127_9225638_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 430.0
HKD2_k127_9225638_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 394.0
HKD2_k127_9225638_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 335.0
HKD2_k127_9225638_5 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 310.0
HKD2_k127_9225638_6 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 314.0
HKD2_k127_9225638_7 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009206 278.0
HKD2_k127_9225638_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002965 241.0
HKD2_k127_9225638_9 4Fe-4S binding domain - - - 0.000000000000000000000000000003923 121.0
HKD2_k127_9231405_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 587.0
HKD2_k127_9231405_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 543.0
HKD2_k127_9231405_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
HKD2_k127_9231405_11 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000001514 184.0
HKD2_k127_9231405_12 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000004629 173.0
HKD2_k127_9231405_13 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000009962 142.0
HKD2_k127_9231405_14 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000005694 133.0
HKD2_k127_9231405_15 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000001752 131.0
HKD2_k127_9231405_16 RNA-binding protein - - - 0.000000000000000003565 94.0
HKD2_k127_9231405_17 - - - - 0.00000000000005606 86.0
HKD2_k127_9231405_18 Rdx family K07401 - - 0.000000000002485 68.0
HKD2_k127_9231405_19 serine threonine protein kinase - - - 0.000000002812 69.0
HKD2_k127_9231405_2 PFAM Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 524.0
HKD2_k127_9231405_20 Peptidase M56 - - - 0.000000006271 68.0
HKD2_k127_9231405_21 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0006375 52.0
HKD2_k127_9231405_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 533.0
HKD2_k127_9231405_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 359.0
HKD2_k127_9231405_5 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 362.0
HKD2_k127_9231405_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 310.0
HKD2_k127_9231405_7 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 254.0
HKD2_k127_9231405_9 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000001055 231.0
HKD2_k127_9243004_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000002813 263.0
HKD2_k127_9250503_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1021.0
HKD2_k127_9250503_1 PFAM peptidase U34 dipeptidase - - - 0.000000000000000000000000000000000000183 146.0
HKD2_k127_9250503_2 Winged helix-turn-helix domain (DUF2582) - - - 0.000000000003674 69.0
HKD2_k127_9261342_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.241e-288 903.0
HKD2_k127_9261342_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.027e-202 637.0
HKD2_k127_9261342_10 spore germination - - - 0.00000000000000000000000000000000000000000000000000005662 198.0
HKD2_k127_9261342_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000001026 170.0
HKD2_k127_9261342_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000006347 132.0
HKD2_k127_9261342_16 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0002224 46.0
HKD2_k127_9261342_2 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 429.0
HKD2_k127_9261342_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
HKD2_k127_9261342_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 311.0
HKD2_k127_9261342_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD2_k127_9261342_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007138 279.0
HKD2_k127_9261342_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002911 257.0
HKD2_k127_9261342_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HKD2_k127_9261342_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006958 192.0
HKD2_k127_9321826_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 6.872e-217 685.0
HKD2_k127_9321826_1 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 596.0
HKD2_k127_9321826_10 - - - - 0.00000000000000000000005047 103.0
HKD2_k127_9321826_11 long-chain fatty acid transport protein - - - 0.0000000000000000002252 95.0
HKD2_k127_9321826_12 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000001225 85.0
HKD2_k127_9321826_2 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 558.0
HKD2_k127_9321826_3 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 442.0
HKD2_k127_9321826_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 277.0
HKD2_k127_9321826_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000002406 201.0
HKD2_k127_9321826_6 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000007269 180.0
HKD2_k127_9321826_7 ECF sigma factor K03088 - - 0.00000000000000000000000000000000003927 142.0
HKD2_k127_9321826_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000002068 104.0
HKD2_k127_9321826_9 Domain of unknown function (DUF4136) - - - 0.00000000000000000000003773 106.0
HKD2_k127_9326092_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 474.0
HKD2_k127_9326092_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HKD2_k127_9326092_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000001751 168.0
HKD2_k127_9326092_3 Helix-turn-helix domain - - - 0.000000000003171 76.0
HKD2_k127_9354050_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.182e-235 735.0
HKD2_k127_9354050_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.71e-220 696.0
HKD2_k127_9354050_10 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000003805 104.0
HKD2_k127_9354050_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000001826 98.0
HKD2_k127_9354050_12 Protein of unknown function (DUF1573) - - - 0.000000000000001033 92.0
HKD2_k127_9354050_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000259 68.0
HKD2_k127_9354050_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00005299 55.0
HKD2_k127_9354050_2 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 517.0
HKD2_k127_9354050_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 351.0
HKD2_k127_9354050_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002054 252.0
HKD2_k127_9354050_5 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
HKD2_k127_9354050_6 receptor K16092 - - 0.000000000000000000000000000000000000000000000001394 195.0
HKD2_k127_9354050_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000008113 156.0
HKD2_k127_9354050_8 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000002687 153.0
HKD2_k127_9354050_9 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.0000000000000000000000001216 123.0
HKD2_k127_9354685_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 473.0
HKD2_k127_9354685_1 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000001729 219.0
HKD2_k127_9354685_2 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000004389 177.0
HKD2_k127_9354685_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000001016 150.0
HKD2_k127_9355820_0 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1118.0
HKD2_k127_9355820_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 4.934e-230 729.0
HKD2_k127_9355820_10 Hydrogenase maturation protease - - - 0.00000000000001304 80.0
HKD2_k127_9355820_2 hydrogenase large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 570.0
HKD2_k127_9355820_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 451.0
HKD2_k127_9355820_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 361.0
HKD2_k127_9355820_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 294.0
HKD2_k127_9355820_6 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
HKD2_k127_9355820_7 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
HKD2_k127_9355820_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001496 247.0
HKD2_k127_9355820_9 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000001431 116.0
HKD2_k127_9368184_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.09e-293 921.0
HKD2_k127_9368184_1 GTP-binding protein TypA K06207 - - 2.726e-258 810.0
HKD2_k127_9368184_10 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
HKD2_k127_9368184_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 329.0
HKD2_k127_9368184_12 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009475 296.0
HKD2_k127_9368184_13 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009179 284.0
HKD2_k127_9368184_14 PFAM Uracil DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001249 249.0
HKD2_k127_9368184_15 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000001412 220.0
HKD2_k127_9368184_16 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000005796 190.0
HKD2_k127_9368184_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000008218 171.0
HKD2_k127_9368184_18 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000003601 164.0
HKD2_k127_9368184_19 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000001099 151.0
HKD2_k127_9368184_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.454e-216 688.0
HKD2_k127_9368184_20 Ubiquinone biosynthesis protein UbiA K02548 - 2.5.1.74 0.0000000000000000000000000000005633 138.0
HKD2_k127_9368184_21 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001097 126.0
HKD2_k127_9368184_22 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000000001194 115.0
HKD2_k127_9368184_23 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.000000000002974 79.0
HKD2_k127_9368184_24 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000003203 76.0
HKD2_k127_9368184_25 DNA polymerase III subunit chi K02339 - 2.7.7.7 0.000000002956 64.0
HKD2_k127_9368184_26 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000009379 66.0
HKD2_k127_9368184_27 Cyclic nucleotide-monophosphate binding domain - - - 0.00000009175 65.0
HKD2_k127_9368184_28 Outer membrane protein (OmpH-like) K06142 - - 0.0000003791 59.0
HKD2_k127_9368184_29 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000004792 57.0
HKD2_k127_9368184_3 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 538.0
HKD2_k127_9368184_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
HKD2_k127_9368184_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 404.0
HKD2_k127_9368184_7 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 392.0
HKD2_k127_9368184_8 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 370.0
HKD2_k127_9368184_9 abc transporter atp-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 360.0
HKD2_k127_9375057_0 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 535.0
HKD2_k127_9375057_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.00000000000000000000000000000000000000001013 165.0
HKD2_k127_9375057_2 TIM barrel - - - 0.0000002502 61.0
HKD2_k127_9433618_0 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000001496 136.0
HKD2_k127_9433618_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000009869 125.0
HKD2_k127_9433618_2 Heavy-metal resistance - - - 0.00000000000002835 79.0
HKD2_k127_9456028_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.539e-294 941.0
HKD2_k127_9456028_1 MmgE/PrpD family K01720 - 4.2.1.79 3.746e-213 686.0
HKD2_k127_9456028_2 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 358.0
HKD2_k127_9456028_3 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000851 277.0
HKD2_k127_9456028_4 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000001823 205.0
HKD2_k127_9456028_5 TIGRFAM TonB K03832 - - 0.00000000000001093 80.0
HKD2_k127_9496510_0 Major Facilitator Superfamily - - - 1.962e-199 632.0
HKD2_k127_9496510_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 477.0
HKD2_k127_9496510_10 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000001133 186.0
HKD2_k127_9496510_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000166 165.0
HKD2_k127_9496510_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002396 149.0
HKD2_k127_9496510_13 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000001881 132.0
HKD2_k127_9496510_14 PDZ domain - - - 0.0000000000000004444 92.0
HKD2_k127_9496510_15 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000001414 81.0
HKD2_k127_9496510_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 398.0
HKD2_k127_9496510_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 378.0
HKD2_k127_9496510_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 376.0
HKD2_k127_9496510_5 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 331.0
HKD2_k127_9496510_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 311.0
HKD2_k127_9496510_7 Psort location CytoplasmicMembrane, score K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
HKD2_k127_9496510_8 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000001616 256.0
HKD2_k127_9496510_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000006406 227.0
HKD2_k127_9522654_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 467.0
HKD2_k127_9522654_1 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
HKD2_k127_9522654_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000005767 173.0
HKD2_k127_9522654_3 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000003224 154.0
HKD2_k127_9522654_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000004026 121.0
HKD2_k127_9522654_5 Protein of unknown function (DUF2723) - - - 0.0000000001689 74.0
HKD2_k127_9528761_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 335.0
HKD2_k127_9528761_1 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000002452 268.0
HKD2_k127_9528761_2 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000002628 183.0
HKD2_k127_9528761_3 response regulator - - - 0.000000000000000000000000001524 116.0
HKD2_k127_9528761_4 Histidine kinase - - - 0.000000000000000000001964 109.0
HKD2_k127_9558739_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 521.0
HKD2_k127_9558739_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 514.0
HKD2_k127_9558739_2 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000003301 190.0
HKD2_k127_9558739_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000002613 170.0
HKD2_k127_9558739_4 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000003305 133.0
HKD2_k127_9558739_5 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000437 102.0
HKD2_k127_9558739_7 PFAM Forkhead-associated protein - - - 0.000000006974 66.0
HKD2_k127_9558739_8 Cytochrome C biogenesis protein K05516 - - 0.000004938 59.0
HKD2_k127_9616613_0 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 331.0
HKD2_k127_9616613_1 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 264.0
HKD2_k127_9627053_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 2.341e-264 827.0
HKD2_k127_9627053_1 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 1.275e-205 649.0
HKD2_k127_9627053_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 439.0
HKD2_k127_9630278_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204 1.2.4.1 0.0 1069.0
HKD2_k127_9630278_1 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 5.668e-197 619.0
HKD2_k127_9630278_10 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 306.0
HKD2_k127_9630278_11 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 313.0
HKD2_k127_9630278_12 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
HKD2_k127_9630278_13 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HKD2_k127_9630278_14 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 275.0
HKD2_k127_9630278_15 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006055 259.0
HKD2_k127_9630278_16 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
HKD2_k127_9630278_17 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000002877 252.0
HKD2_k127_9630278_18 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000004862 220.0
HKD2_k127_9630278_19 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000001197 211.0
HKD2_k127_9630278_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 546.0
HKD2_k127_9630278_20 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000001325 171.0
HKD2_k127_9630278_21 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000003435 163.0
HKD2_k127_9630278_22 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000001364 163.0
HKD2_k127_9630278_23 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000002702 163.0
HKD2_k127_9630278_24 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000003165 154.0
HKD2_k127_9630278_25 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000000000001997 145.0
HKD2_k127_9630278_26 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000001035 137.0
HKD2_k127_9630278_27 Receptor family ligand binding region - - - 0.000000000000000000000000000001197 135.0
HKD2_k127_9630278_28 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000555 109.0
HKD2_k127_9630278_29 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000001309 115.0
HKD2_k127_9630278_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 508.0
HKD2_k127_9630278_30 Glycosyl transferase K20444 - - 0.00000000000000000004038 106.0
HKD2_k127_9630278_31 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000000001445 86.0
HKD2_k127_9630278_32 Bacterial membrane protein, YfhO - - - 0.00000000000008853 85.0
HKD2_k127_9630278_33 Protein of unknown function (DUF3891) - - - 0.000000000003289 76.0
HKD2_k127_9630278_34 Bacterial membrane protein, YfhO - - - 0.0000000000273 77.0
HKD2_k127_9630278_35 Bacterial membrane protein YfhO - - - 0.000000001697 71.0
HKD2_k127_9630278_36 general secretion pathway protein K02456 - - 0.000000001916 66.0
HKD2_k127_9630278_37 -O-antigen K02847,K13009 - - 0.00000005886 66.0
HKD2_k127_9630278_38 Glycosyl transferase family 41 - - - 0.0000007715 62.0
HKD2_k127_9630278_39 Bacterial membrane protein YfhO - - - 0.000005161 60.0
HKD2_k127_9630278_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 426.0
HKD2_k127_9630278_41 -O-antigen K07234 - - 0.000006796 59.0
HKD2_k127_9630278_42 Alpha beta - - - 0.00002147 56.0
HKD2_k127_9630278_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 415.0
HKD2_k127_9630278_6 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 402.0
HKD2_k127_9630278_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 353.0
HKD2_k127_9630278_8 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 338.0
HKD2_k127_9630278_9 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 316.0
HKD2_k127_9769498_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.012e-287 906.0
HKD2_k127_9769498_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 9.876e-255 823.0
HKD2_k127_9769498_10 Lipopolysaccharide-assembly - - - 0.00000000000002333 81.0
HKD2_k127_9769498_11 Helix-turn-helix XRE-family like proteins - - - 0.0000002301 62.0
HKD2_k127_9769498_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000005794 59.0
HKD2_k127_9769498_13 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000006854 57.0
HKD2_k127_9769498_14 Peptidase S24-like - - - 0.00002286 55.0
HKD2_k127_9769498_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.699e-251 788.0
HKD2_k127_9769498_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 6.431e-217 681.0
HKD2_k127_9769498_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000005508 207.0
HKD2_k127_9769498_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD2_k127_9769498_6 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000001481 206.0
HKD2_k127_9769498_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000002607 128.0
HKD2_k127_9769498_8 recA bacterial DNA recombination protein - - - 0.0000000000000000000002105 109.0
HKD2_k127_9769498_9 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000001347 106.0
HKD2_k127_9860407_0 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 541.0
HKD2_k127_9860407_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 422.0
HKD2_k127_9860407_10 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000007482 135.0
HKD2_k127_9860407_11 Domain of unknown function (DUF4198) - - - 0.000000000002923 78.0
HKD2_k127_9860407_2 TIGRFAM phage plasmid-related protein TIGR03299 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 363.0
HKD2_k127_9860407_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 298.0
HKD2_k127_9860407_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
HKD2_k127_9860407_5 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000001012 226.0
HKD2_k127_9860407_6 DNA recombination - - - 0.00000000000000000000000000000000000000000000000000000005471 205.0
HKD2_k127_9860407_7 Virulence-associated protein E - - - 0.00000000000000000000000000000000000000000000000000001155 212.0
HKD2_k127_9860407_8 response to copper ion K16915 - - 0.000000000000000000000000000000000000002692 151.0
HKD2_k127_9860407_9 Bifunctional DNA primase/polymerase, N-terminal - - - 0.00000000000000000000000000006595 130.0