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Overview

ID MAG01834
Name HKD3_bin.11
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus
Species
Assembly information
Completeness (%) 92.73
Contamination (%) 5.96
GC content (%) 74.0
N50 (bp) 13,264
Genome size (bp) 3,395,068

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2970

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_101337_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.227e-293 908.0
HKD3_k127_101337_1 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 494.0
HKD3_k127_101337_2 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000009932 178.0
HKD3_k127_101337_3 OmpA family K03286 - - 0.000000000001436 78.0
HKD3_k127_114031_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1263.0
HKD3_k127_114031_1 Cation transporter/ATPase, N-terminus K01537,K01539 - 3.6.3.8,3.6.3.9 7.261e-277 880.0
HKD3_k127_114031_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000003594 263.0
HKD3_k127_114031_11 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000007427 210.0
HKD3_k127_114031_12 Adenylylsulfate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000007067 208.0
HKD3_k127_114031_13 Response regulator, receiver - - - 0.00000000000000000000000004405 116.0
HKD3_k127_114031_15 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000001506 112.0
HKD3_k127_114031_16 BON domain - - - 0.000000000000004509 76.0
HKD3_k127_114031_2 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 4.042e-233 748.0
HKD3_k127_114031_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 509.0
HKD3_k127_114031_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 522.0
HKD3_k127_114031_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 458.0
HKD3_k127_114031_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 426.0
HKD3_k127_114031_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 354.0
HKD3_k127_114031_8 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 344.0
HKD3_k127_114031_9 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
HKD3_k127_1208266_0 Homospermidine synthase K00808 - 2.5.1.44 2.947e-253 789.0
HKD3_k127_1208266_1 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 7.567e-199 625.0
HKD3_k127_1208266_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 3.758e-196 653.0
HKD3_k127_1208266_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 554.0
HKD3_k127_1208266_4 Domain of unknown function(DUF2779) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 373.0
HKD3_k127_1208266_5 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 327.0
HKD3_k127_1208266_6 Major facilitator superfamily MFS_1 K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000009729 249.0
HKD3_k127_1208266_7 acyl-coa-binding protein - - - 0.0000000000000000000000124 112.0
HKD3_k127_1208266_8 Domain of unknown function (DUF4912) K09942 - - 0.00000000000003112 86.0
HKD3_k127_1208266_9 fibroblast growth factor binding - - - 0.00000000000003301 81.0
HKD3_k127_1211936_0 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 8.701e-236 740.0
HKD3_k127_1211936_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.677e-199 625.0
HKD3_k127_1211936_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 586.0
HKD3_k127_1211936_3 COG2826 Transposase and inactivated derivatives, IS30 family K07482 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 503.0
HKD3_k127_1211936_4 Biotin-requiring enzyme - - - 0.000000000000000000000000000000000000000000000000004094 209.0
HKD3_k127_1215143_0 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 452.0
HKD3_k127_1215143_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 428.0
HKD3_k127_1215143_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 375.0
HKD3_k127_1215143_3 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 322.0
HKD3_k127_1215143_4 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000005558 233.0
HKD3_k127_1215143_5 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000006072 224.0
HKD3_k127_1215143_6 cobalamin binding K03496,K22491 - - 0.00000000000000000000000000000000000000000000000002359 188.0
HKD3_k127_1226890_0 Large family of predicted nucleotide-binding domains K07175 - - 1.177e-241 752.0
HKD3_k127_1226890_1 diguanylate cyclase - - - 1.527e-221 710.0
HKD3_k127_1226890_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 499.0
HKD3_k127_1226890_3 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 458.0
HKD3_k127_1226890_4 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000002778 201.0
HKD3_k127_1226890_5 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000003418 104.0
HKD3_k127_1226890_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000003997 70.0
HKD3_k127_1253895_0 repeat protein - - - 0.0 4333.0
HKD3_k127_1253895_1 Tetratricopeptide repeat - - - 0.0 1305.0
HKD3_k127_1253895_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 394.0
HKD3_k127_1253895_11 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007332 289.0
HKD3_k127_1253895_12 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
HKD3_k127_1253895_13 RDD family K18481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004012 277.0
HKD3_k127_1253895_14 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000448 277.0
HKD3_k127_1253895_15 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
HKD3_k127_1253895_16 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 289.0
HKD3_k127_1253895_18 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000000000000000000000000001822 229.0
HKD3_k127_1253895_2 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1107.0
HKD3_k127_1253895_20 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000000001215 182.0
HKD3_k127_1253895_22 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000299 155.0
HKD3_k127_1253895_23 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000001745 158.0
HKD3_k127_1253895_24 - - - - 0.0000000000000000000000000000000078 133.0
HKD3_k127_1253895_3 FHA domain - - - 3.061e-241 764.0
HKD3_k127_1253895_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 618.0
HKD3_k127_1253895_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 612.0
HKD3_k127_1253895_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 581.0
HKD3_k127_1253895_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 584.0
HKD3_k127_1253895_8 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 514.0
HKD3_k127_1253895_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 421.0
HKD3_k127_1255772_0 FAD linked oxidase domain protein - - - 0.0 1721.0
HKD3_k127_1255772_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.216e-234 745.0
HKD3_k127_1255772_10 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000001399 139.0
HKD3_k127_1255772_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.175e-213 685.0
HKD3_k127_1255772_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
HKD3_k127_1255772_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001985 250.0
HKD3_k127_1255772_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003692 254.0
HKD3_k127_1255772_6 epimerase K00091,K01007,K02377,K07118,K19073,K19267 - 1.1.1.219,1.1.1.271,1.3.1.75,1.6.5.2,2.7.9.2 0.0000000000000000000000000000000000000000000000000000003306 208.0
HKD3_k127_1255772_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000003519 151.0
HKD3_k127_1255772_8 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000001014 141.0
HKD3_k127_1255772_9 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000000008357 127.0
HKD3_k127_1256941_0 Belongs to the ClpA ClpB family K03694 - - 1.069e-264 839.0
HKD3_k127_1256941_1 Dienelactone hydrolase family - - - 2.132e-256 806.0
HKD3_k127_1256941_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
HKD3_k127_1256941_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000003505 139.0
HKD3_k127_1260072_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.308e-251 783.0
HKD3_k127_1260072_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 388.0
HKD3_k127_1260072_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000009382 163.0
HKD3_k127_1260072_3 zinc transporter K07238 - - 0.0000000000000000000000000000000000000171 154.0
HKD3_k127_1269277_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1690.0
HKD3_k127_1269277_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0 1054.0
HKD3_k127_1269277_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 411.0
HKD3_k127_1269277_11 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 421.0
HKD3_k127_1269277_12 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 397.0
HKD3_k127_1269277_13 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 443.0
HKD3_k127_1269277_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 377.0
HKD3_k127_1269277_15 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 389.0
HKD3_k127_1269277_16 Acyltransferase, ws dgat mgat K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 381.0
HKD3_k127_1269277_17 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 383.0
HKD3_k127_1269277_18 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 391.0
HKD3_k127_1269277_19 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 358.0
HKD3_k127_1269277_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1018.0
HKD3_k127_1269277_20 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 345.0
HKD3_k127_1269277_21 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 344.0
HKD3_k127_1269277_22 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 302.0
HKD3_k127_1269277_23 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 259.0
HKD3_k127_1269277_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000001166 248.0
HKD3_k127_1269277_25 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000454 251.0
HKD3_k127_1269277_26 Methyl-transferase K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000275 233.0
HKD3_k127_1269277_27 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000008672 190.0
HKD3_k127_1269277_29 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000005614 173.0
HKD3_k127_1269277_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 3.163e-217 679.0
HKD3_k127_1269277_30 Scavenger mRNA decapping enzyme C-term binding - - - 0.000000000000000000000000000000000000000001982 162.0
HKD3_k127_1269277_31 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000007136 156.0
HKD3_k127_1269277_32 Cold-shock protein K03704 - - 0.000000000000000000000000000000000001806 139.0
HKD3_k127_1269277_33 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000001295 117.0
HKD3_k127_1269277_34 - - - - 0.0000000000000000003057 97.0
HKD3_k127_1269277_35 PilZ domain - - - 0.000000000000001029 85.0
HKD3_k127_1269277_37 Hsp33 protein K04083 - - 0.0000000000004662 70.0
HKD3_k127_1269277_39 Collagen type IX alpha 3 K08131 GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0005581,GO:0005593,GO:0005594,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030020,GO:0030198,GO:0031974,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071840 - 0.000000000003128 78.0
HKD3_k127_1269277_4 zinc-ribbon domain - - - 4.669e-203 672.0
HKD3_k127_1269277_41 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000001762 58.0
HKD3_k127_1269277_5 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 563.0
HKD3_k127_1269277_6 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 530.0
HKD3_k127_1269277_7 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 507.0
HKD3_k127_1269277_8 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 511.0
HKD3_k127_1269277_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 428.0
HKD3_k127_12732_0 transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 492.0
HKD3_k127_12732_1 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 330.0
HKD3_k127_12732_11 Protein of unknown function (DUF3617) - - - 0.00000000000000000000006141 110.0
HKD3_k127_12732_12 Domain of unknown function (DUF4340) - - - 0.0000002703 64.0
HKD3_k127_12732_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002383 293.0
HKD3_k127_12732_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
HKD3_k127_12732_4 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001168 252.0
HKD3_k127_12732_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000008137 252.0
HKD3_k127_12732_6 Belongs to the peptidase S11 family K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000009238 235.0
HKD3_k127_12732_7 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000368 211.0
HKD3_k127_12732_8 - - - - 0.000000000000000000000000000000000000000000000001898 199.0
HKD3_k127_12732_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000001069 164.0
HKD3_k127_129257_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1423.0
HKD3_k127_129257_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.458e-315 977.0
HKD3_k127_129257_2 Patatin-like phospholipase - - - 8.105e-213 679.0
HKD3_k127_129257_3 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 499.0
HKD3_k127_129257_4 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
HKD3_k127_129257_5 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 330.0
HKD3_k127_129257_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001738 241.0
HKD3_k127_129257_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0001024 46.0
HKD3_k127_1321039_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 543.0
HKD3_k127_1321039_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
HKD3_k127_1321039_2 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000003035 148.0
HKD3_k127_1324149_0 ABC transporter C-terminal domain K06158 - - 1.393e-290 905.0
HKD3_k127_1324149_1 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 542.0
HKD3_k127_1324149_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 423.0
HKD3_k127_1324149_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
HKD3_k127_1324149_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001754 290.0
HKD3_k127_1324149_5 Outer Membrane Lipoprotein K03098 - - 0.0000000000000000000000000000000000000000000000000044 189.0
HKD3_k127_1324149_6 - - - - 0.0000000000000000000000000000000000000000000001017 182.0
HKD3_k127_1324149_7 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000286 141.0
HKD3_k127_1342980_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 5.216e-243 770.0
HKD3_k127_1342980_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
HKD3_k127_1342980_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004024 194.0
HKD3_k127_1342980_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000006146 196.0
HKD3_k127_1342980_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000002334 136.0
HKD3_k127_1342980_6 response regulator - - - 0.000000000000000000000000000006384 121.0
HKD3_k127_1357726_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.59e-228 733.0
HKD3_k127_1357726_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.389e-195 626.0
HKD3_k127_1357726_10 TPR repeat - - - 0.0000000000000000000000000000000000000000000003567 188.0
HKD3_k127_1357726_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000004726 84.0
HKD3_k127_1357726_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 604.0
HKD3_k127_1357726_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 445.0
HKD3_k127_1357726_4 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 475.0
HKD3_k127_1357726_5 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 423.0
HKD3_k127_1357726_6 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 415.0
HKD3_k127_1357726_7 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 280.0
HKD3_k127_1357726_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000001148 231.0
HKD3_k127_1357726_9 TPR repeat - - - 0.000000000000000000000000000000000000000000000000007156 191.0
HKD3_k127_1397629_0 Sulfatase K01130 - 3.1.6.1 0.0 1470.0
HKD3_k127_1397629_1 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 291.0
HKD3_k127_1397629_2 - - - - 0.000000000009996 70.0
HKD3_k127_1397629_3 - - - - 0.00000007391 63.0
HKD3_k127_1434763_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.513e-218 691.0
HKD3_k127_1434763_1 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 415.0
HKD3_k127_1434763_10 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000004971 138.0
HKD3_k127_1434763_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 374.0
HKD3_k127_1434763_3 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 353.0
HKD3_k127_1434763_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
HKD3_k127_1434763_5 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009581 259.0
HKD3_k127_1434763_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003646 252.0
HKD3_k127_1434763_7 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000009558 248.0
HKD3_k127_1434763_8 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002557 222.0
HKD3_k127_1434763_9 - - - - 0.000000000000000000000000000000000000000000000000009451 183.0
HKD3_k127_1452061_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 6.522e-205 659.0
HKD3_k127_1452061_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000004663 181.0
HKD3_k127_1452061_2 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000003122 139.0
HKD3_k127_1452061_3 RarD protein K05786 - - 0.000000000000000000007743 94.0
HKD3_k127_1459785_0 Amino acid permease - - - 2.139e-283 886.0
HKD3_k127_1459785_1 ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 531.0
HKD3_k127_1459785_2 PBP superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 395.0
HKD3_k127_1459785_3 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 359.0
HKD3_k127_1459785_4 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 331.0
HKD3_k127_1459785_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 324.0
HKD3_k127_1459785_6 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 312.0
HKD3_k127_1459785_7 transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 251.0
HKD3_k127_1459785_8 Domain of unknown function (DUF4136) - - - 0.00001492 55.0
HKD3_k127_1474194_0 Signal transduction histidine kinase - - - 9.344e-305 945.0
HKD3_k127_1474194_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 1.561e-252 784.0
HKD3_k127_1508681_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1047.0
HKD3_k127_1508681_1 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000000000000000000000000000000000000000000000000001397 228.0
HKD3_k127_1508681_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000005046 220.0
HKD3_k127_1508681_4 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000004262 164.0
HKD3_k127_154835_0 Histidine kinase HAMP - - - 6.607e-209 661.0
HKD3_k127_154835_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 507.0
HKD3_k127_154835_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 413.0
HKD3_k127_154835_3 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 422.0
HKD3_k127_154835_4 PhoQ Sensor - - - 0.0000000000000000000000000103 114.0
HKD3_k127_154837_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 300.0
HKD3_k127_154837_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003944 258.0
HKD3_k127_154837_2 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HKD3_k127_154837_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009425 255.0
HKD3_k127_154837_4 Receptor family ligand binding region K01999 - - 0.00000000000000000001176 94.0
HKD3_k127_160140_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
HKD3_k127_160140_1 Pfam:Methyltransf_26 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 313.0
HKD3_k127_160140_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002159 286.0
HKD3_k127_160140_3 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000001492 190.0
HKD3_k127_160140_4 transcriptional regulator K13643 - - 0.00000000000000000000001055 105.0
HKD3_k127_160140_5 Glycosyltransferase family 87 - - - 0.0000000000000000000002202 110.0
HKD3_k127_1612230_0 secondary active sulfate transmembrane transporter activity K06901 - - 4.712e-201 635.0
HKD3_k127_1612230_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 643.0
HKD3_k127_1612230_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 310.0
HKD3_k127_1621103_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1083.0
HKD3_k127_1621103_1 FtsX-like permease family K02004 - - 1.073e-281 903.0
HKD3_k127_1621103_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.532e-277 856.0
HKD3_k127_1621103_3 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 385.0
HKD3_k127_1621103_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 304.0
HKD3_k127_1621103_5 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 286.0
HKD3_k127_1621103_6 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007923 274.0
HKD3_k127_1621103_7 short-chain dehydrogenase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000005995 242.0
HKD3_k127_1621103_9 - - - - 0.000000000000000000000000000001121 141.0
HKD3_k127_1622057_0 hydrolase activity, acting on ester bonds K01563,K11991 - 3.5.4.33,3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 289.0
HKD3_k127_1622057_1 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000334 142.0
HKD3_k127_1622057_2 Ion channel - - - 0.000000000000000000002156 105.0
HKD3_k127_1668217_0 Periplasmic binding protein domain K01999 - - 2.846e-205 655.0
HKD3_k127_1668217_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 512.0
HKD3_k127_1668217_10 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 379.0
HKD3_k127_1668217_11 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000807 309.0
HKD3_k127_1668217_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000001665 171.0
HKD3_k127_1668217_13 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000001265 187.0
HKD3_k127_1668217_14 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000141 160.0
HKD3_k127_1668217_16 Nuclease-related domain - - - 0.000000000000000000000000000000000002145 158.0
HKD3_k127_1668217_17 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000009396 138.0
HKD3_k127_1668217_19 geranylgeranyl reductase - - - 0.000000000000000000000000000218 133.0
HKD3_k127_1668217_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 491.0
HKD3_k127_1668217_21 Ammonium Transporter K03320 - - 0.0000000000000000000003101 98.0
HKD3_k127_1668217_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 489.0
HKD3_k127_1668217_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 492.0
HKD3_k127_1668217_5 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 466.0
HKD3_k127_1668217_6 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 455.0
HKD3_k127_1668217_7 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
HKD3_k127_1668217_8 S-adenosylmethionine synthetase, C-terminal domain K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 445.0
HKD3_k127_1668217_9 ABC transporter K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 374.0
HKD3_k127_167789_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 399.0
HKD3_k127_167789_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009217 265.0
HKD3_k127_167789_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000002876 195.0
HKD3_k127_167789_3 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000002017 198.0
HKD3_k127_167789_4 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000001822 162.0
HKD3_k127_167789_6 Transcriptional regulator - - - 0.00000002274 59.0
HKD3_k127_1738844_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 493.0
HKD3_k127_1738844_1 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 310.0
HKD3_k127_1738844_2 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
HKD3_k127_1738844_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004834 274.0
HKD3_k127_1796034_0 Tetratricopeptide repeat - - - 2.314e-255 856.0
HKD3_k127_1796034_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 369.0
HKD3_k127_1796034_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 344.0
HKD3_k127_1796034_3 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 341.0
HKD3_k127_1796034_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
HKD3_k127_1796034_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004978 268.0
HKD3_k127_1796034_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000365 254.0
HKD3_k127_1796034_7 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008577 224.0
HKD3_k127_1796034_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000004909 104.0
HKD3_k127_179809_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.722e-215 705.0
HKD3_k127_179809_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.012e-196 614.0
HKD3_k127_179809_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 528.0
HKD3_k127_179809_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 328.0
HKD3_k127_179809_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001958 248.0
HKD3_k127_179809_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000001675 64.0
HKD3_k127_1807111_0 DNA helicase K03656,K03657 - 3.6.4.12 8.142e-305 947.0
HKD3_k127_1807111_1 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 551.0
HKD3_k127_1807111_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 481.0
HKD3_k127_1807111_3 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 308.0
HKD3_k127_1807111_4 iron ion binding - - - 0.000000000000000000000000000000000000000001297 181.0
HKD3_k127_1807111_5 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000008333 139.0
HKD3_k127_1807111_6 Dodecin K09165 - - 0.000000000000000000000000105 109.0
HKD3_k127_1807111_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000005095 81.0
HKD3_k127_1812586_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1092.0
HKD3_k127_1812586_1 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 421.0
HKD3_k127_1812586_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 319.0
HKD3_k127_1812586_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 294.0
HKD3_k127_1812586_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000004375 233.0
HKD3_k127_1812586_6 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000009362 207.0
HKD3_k127_1812586_7 peptidase M23 - - - 0.00000000000000000000000000000000007494 142.0
HKD3_k127_1839280_0 acyl-CoA dehydrogenase K06446 - - 2.055e-291 904.0
HKD3_k127_1839280_1 AsmA family K07289 - - 2.049e-212 689.0
HKD3_k127_1839280_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 479.0
HKD3_k127_1839280_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 436.0
HKD3_k127_1839280_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001205 233.0
HKD3_k127_1839280_5 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000004113 243.0
HKD3_k127_1839280_6 META domain - - - 0.0000000000000000000000000000000000000001537 172.0
HKD3_k127_1839280_7 WHG domain - - - 0.0000000000000000000000000000002641 134.0
HKD3_k127_1839280_8 Nitroreductase family - - - 0.0000000000000000000001209 102.0
HKD3_k127_1852146_0 - - - - 0.0 1007.0
HKD3_k127_1852146_1 CoA-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 567.0
HKD3_k127_1852146_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 350.0
HKD3_k127_1852146_3 KR domain K07124 - - 0.00000000000000000000000000000001547 131.0
HKD3_k127_1852146_4 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000006099 114.0
HKD3_k127_1957149_0 uridine kinase K00876 - 2.7.1.48 1.529e-301 941.0
HKD3_k127_1957149_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.013e-254 790.0
HKD3_k127_1957149_10 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 467.0
HKD3_k127_1957149_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 458.0
HKD3_k127_1957149_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 437.0
HKD3_k127_1957149_13 ABC transporter, ATP-binding protein K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 428.0
HKD3_k127_1957149_14 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 431.0
HKD3_k127_1957149_15 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 343.0
HKD3_k127_1957149_16 Oligoendopeptidase f - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 345.0
HKD3_k127_1957149_17 Response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000762 282.0
HKD3_k127_1957149_18 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
HKD3_k127_1957149_19 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001521 207.0
HKD3_k127_1957149_2 serine threonine protein kinase K12132 - 2.7.11.1 3.801e-238 749.0
HKD3_k127_1957149_20 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000001722 194.0
HKD3_k127_1957149_21 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000008055 179.0
HKD3_k127_1957149_23 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000008882 128.0
HKD3_k127_1957149_25 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.000000000000000000002773 104.0
HKD3_k127_1957149_26 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000234 105.0
HKD3_k127_1957149_3 penicillin-binding protein K03587 - 3.4.16.4 4.166e-225 726.0
HKD3_k127_1957149_4 Histidine kinase - - - 4.675e-196 626.0
HKD3_k127_1957149_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 613.0
HKD3_k127_1957149_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 607.0
HKD3_k127_1957149_7 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 533.0
HKD3_k127_1957149_8 PFAM NMT1 THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 499.0
HKD3_k127_1957149_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 484.0
HKD3_k127_2084073_0 glutaminyl-tRNA K01886 - 6.1.1.18 3.092e-273 844.0
HKD3_k127_2084073_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 484.0
HKD3_k127_2084073_2 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000002794 243.0
HKD3_k127_2084073_3 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000000000000000000000000000000000000003653 184.0
HKD3_k127_2132031_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 620.0
HKD3_k127_2132031_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 480.0
HKD3_k127_2132031_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000678 215.0
HKD3_k127_2132031_4 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000001652 168.0
HKD3_k127_2132031_5 Chemotaxis protein CheY K03413 - - 0.000000000000000000000000000000000002179 145.0
HKD3_k127_2132031_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000009748 139.0
HKD3_k127_215347_0 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 402.0
HKD3_k127_215347_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 407.0
HKD3_k127_215347_2 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 385.0
HKD3_k127_215347_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001046 274.0
HKD3_k127_215347_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
HKD3_k127_215347_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000182 246.0
HKD3_k127_215347_6 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000000003458 229.0
HKD3_k127_215347_7 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000000004456 196.0
HKD3_k127_215347_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000009283 93.0
HKD3_k127_215347_9 PFAM response regulator receiver - - - 0.00002914 51.0
HKD3_k127_2247966_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1705.0
HKD3_k127_2247966_1 Heat shock 70 kDa protein K04043 - - 6.912e-318 983.0
HKD3_k127_2247966_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 515.0
HKD3_k127_2247966_11 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 512.0
HKD3_k127_2247966_12 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 412.0
HKD3_k127_2247966_13 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 396.0
HKD3_k127_2247966_14 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
HKD3_k127_2247966_15 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 372.0
HKD3_k127_2247966_16 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 389.0
HKD3_k127_2247966_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 361.0
HKD3_k127_2247966_18 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 336.0
HKD3_k127_2247966_19 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 321.0
HKD3_k127_2247966_2 SMART helicase c2 K03722 - 3.6.4.12 2.406e-294 924.0
HKD3_k127_2247966_20 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000001494 244.0
HKD3_k127_2247966_21 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000258 229.0
HKD3_k127_2247966_22 ATP synthesis coupled proton transport K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000752 224.0
HKD3_k127_2247966_23 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000005107 225.0
HKD3_k127_2247966_24 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000004727 219.0
HKD3_k127_2247966_25 chemotaxis K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.000000000000000000000000000000000000000000000000000005184 216.0
HKD3_k127_2247966_27 chemotaxis K02659,K03408 - - 0.000000000000000000000000000000000000000932 168.0
HKD3_k127_2247966_29 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000002594 110.0
HKD3_k127_2247966_3 ABC-type branched-chain amino acid transport K07121 - - 2.399e-225 717.0
HKD3_k127_2247966_30 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000005485 61.0
HKD3_k127_2247966_4 Histidine kinase - - - 2.098e-215 687.0
HKD3_k127_2247966_5 PFAM ATP-binding region ATPase domain protein - - - 1.735e-201 659.0
HKD3_k127_2247966_6 histidine kinase HAMP region domain protein K03406 - - 3.961e-198 627.0
HKD3_k127_2247966_7 P2 response regulator binding domain K03407 - 2.7.13.3 8.897e-197 633.0
HKD3_k127_2247966_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 602.0
HKD3_k127_2247966_9 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 527.0
HKD3_k127_225714_0 Protein of unknown function, DUF255 K06888 - - 0.0 1036.0
HKD3_k127_225714_1 Belongs to the RtcB family K14415 - 6.5.1.3 3.718e-243 766.0
HKD3_k127_225714_10 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000004247 177.0
HKD3_k127_225714_11 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000006563 175.0
HKD3_k127_225714_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 591.0
HKD3_k127_225714_3 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 526.0
HKD3_k127_225714_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 511.0
HKD3_k127_225714_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 470.0
HKD3_k127_225714_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 422.0
HKD3_k127_225714_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002012 280.0
HKD3_k127_225714_8 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000002322 237.0
HKD3_k127_225714_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000663 203.0
HKD3_k127_229545_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 9.683e-194 614.0
HKD3_k127_229545_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 537.0
HKD3_k127_229545_2 DUF1704 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 504.0
HKD3_k127_229545_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 321.0
HKD3_k127_229545_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 323.0
HKD3_k127_229545_5 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 303.0
HKD3_k127_229545_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000006035 234.0
HKD3_k127_231740_0 helicase - - - 0.0 1150.0
HKD3_k127_231740_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0 1109.0
HKD3_k127_231740_11 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 320.0
HKD3_k127_231740_12 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000004173 254.0
HKD3_k127_231740_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000002571 241.0
HKD3_k127_231740_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000003914 224.0
HKD3_k127_231740_15 fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000008787 222.0
HKD3_k127_231740_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000001426 182.0
HKD3_k127_231740_17 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000004932 177.0
HKD3_k127_231740_18 PFAM DoxX family protein - - - 0.000000000000000000000000000000000002895 151.0
HKD3_k127_231740_19 Transporter associated domain K03699 - - 0.0000000000000000000000000000004335 131.0
HKD3_k127_231740_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1084.0
HKD3_k127_231740_20 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000000176 110.0
HKD3_k127_231740_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 3.2e-276 858.0
HKD3_k127_231740_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.885e-273 849.0
HKD3_k127_231740_5 exonuclease activity K16899 - 3.6.4.12 1.51e-249 804.0
HKD3_k127_231740_6 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 503.0
HKD3_k127_231740_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 456.0
HKD3_k127_231740_8 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 468.0
HKD3_k127_231740_9 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 395.0
HKD3_k127_2351940_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2125.0
HKD3_k127_2351940_1 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 9.323e-255 792.0
HKD3_k127_2351940_2 PFAM major facilitator superfamily MFS_1 K02575 - - 3.428e-216 694.0
HKD3_k127_2351940_3 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 438.0
HKD3_k127_2351940_4 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000006463 237.0
HKD3_k127_2351940_5 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000006088 225.0
HKD3_k127_2351940_6 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000001482 147.0
HKD3_k127_2351940_7 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000008496 144.0
HKD3_k127_2351940_8 Cytochrome c - - - 0.00000000000000000000000000002015 124.0
HKD3_k127_2351940_9 PFAM Uncharacterised ArCR, COG2043 - - - 0.0006648 44.0
HKD3_k127_2422174_0 FeS assembly protein SufB K09014 - - 1.168e-279 871.0
HKD3_k127_2422174_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 3.571e-268 830.0
HKD3_k127_2422174_10 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 383.0
HKD3_k127_2422174_11 Methyltransferase type 11 K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
HKD3_k127_2422174_12 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 363.0
HKD3_k127_2422174_13 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 318.0
HKD3_k127_2422174_14 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 314.0
HKD3_k127_2422174_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 283.0
HKD3_k127_2422174_16 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 285.0
HKD3_k127_2422174_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000561 274.0
HKD3_k127_2422174_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004216 274.0
HKD3_k127_2422174_19 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000936 266.0
HKD3_k127_2422174_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 621.0
HKD3_k127_2422174_20 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004278 283.0
HKD3_k127_2422174_21 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004796 258.0
HKD3_k127_2422174_22 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000003922 220.0
HKD3_k127_2422174_23 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000292 217.0
HKD3_k127_2422174_24 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000000000000000000000000000000000000000000000004584 198.0
HKD3_k127_2422174_26 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000001329 194.0
HKD3_k127_2422174_27 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000001206 160.0
HKD3_k127_2422174_28 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000008263 154.0
HKD3_k127_2422174_29 histone H2A K63-linked ubiquitination K02283 - - 0.000000000000000000000000000000000000009995 162.0
HKD3_k127_2422174_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 595.0
HKD3_k127_2422174_30 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000009481 137.0
HKD3_k127_2422174_31 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000014 136.0
HKD3_k127_2422174_33 YMGG-like Gly-zipper - - - 0.0000000000000001304 93.0
HKD3_k127_2422174_4 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 520.0
HKD3_k127_2422174_5 Aldo keto reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 458.0
HKD3_k127_2422174_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 459.0
HKD3_k127_2422174_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 383.0
HKD3_k127_2422174_8 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 398.0
HKD3_k127_2422174_9 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 379.0
HKD3_k127_242788_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.435e-227 713.0
HKD3_k127_242788_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 564.0
HKD3_k127_242788_10 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000006752 204.0
HKD3_k127_242788_11 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000406 200.0
HKD3_k127_242788_12 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000296 173.0
HKD3_k127_242788_14 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000001181 117.0
HKD3_k127_242788_15 Protein of unknown function (DUF3106) - - - 0.000000000000007876 86.0
HKD3_k127_242788_16 Putative zinc-finger - - - 0.0000000001368 73.0
HKD3_k127_242788_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 524.0
HKD3_k127_242788_3 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 522.0
HKD3_k127_242788_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 400.0
HKD3_k127_242788_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 377.0
HKD3_k127_242788_6 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 324.0
HKD3_k127_242788_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
HKD3_k127_242788_8 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000004836 249.0
HKD3_k127_242788_9 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000129 204.0
HKD3_k127_2447968_0 CoA binding domain K09181 - - 4.438e-314 995.0
HKD3_k127_2447968_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.044e-242 755.0
HKD3_k127_2447968_10 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 566.0
HKD3_k127_2447968_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 527.0
HKD3_k127_2447968_12 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 508.0
HKD3_k127_2447968_13 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 467.0
HKD3_k127_2447968_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 406.0
HKD3_k127_2447968_15 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 390.0
HKD3_k127_2447968_16 Enoyl-CoA hydratase/isomerase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 410.0
HKD3_k127_2447968_17 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 364.0
HKD3_k127_2447968_18 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 350.0
HKD3_k127_2447968_19 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 341.0
HKD3_k127_2447968_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.553e-231 734.0
HKD3_k127_2447968_20 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 324.0
HKD3_k127_2447968_21 Alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 333.0
HKD3_k127_2447968_22 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HKD3_k127_2447968_23 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 302.0
HKD3_k127_2447968_24 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009261 292.0
HKD3_k127_2447968_25 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001771 293.0
HKD3_k127_2447968_26 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000005822 223.0
HKD3_k127_2447968_27 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000001323 230.0
HKD3_k127_2447968_28 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001048 203.0
HKD3_k127_2447968_29 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000001412 138.0
HKD3_k127_2447968_3 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 2.728e-229 721.0
HKD3_k127_2447968_4 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 6.953e-224 711.0
HKD3_k127_2447968_5 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 1.628e-209 659.0
HKD3_k127_2447968_6 acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.333e-201 634.0
HKD3_k127_2447968_7 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 7.985e-196 623.0
HKD3_k127_2447968_8 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 1.176e-194 634.0
HKD3_k127_2447968_9 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 622.0
HKD3_k127_244913_0 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 542.0
HKD3_k127_244913_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 503.0
HKD3_k127_244913_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 515.0
HKD3_k127_244913_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 468.0
HKD3_k127_244913_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000001865 247.0
HKD3_k127_2460266_0 PFAM MMPL family K07003 - - 0.0 1014.0
HKD3_k127_2460266_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 331.0
HKD3_k127_2460266_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 293.0
HKD3_k127_2460266_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002479 274.0
HKD3_k127_2460266_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000006479 215.0
HKD3_k127_2460266_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000004097 169.0
HKD3_k127_2460266_6 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000818 163.0
HKD3_k127_2460266_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000003319 132.0
HKD3_k127_2460266_8 - - - - 0.0000000000000000000001034 106.0
HKD3_k127_2466525_0 PFAM response regulator receiver K07713 - - 6.404e-231 723.0
HKD3_k127_2466525_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 565.0
HKD3_k127_2466525_10 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 354.0
HKD3_k127_2466525_11 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HKD3_k127_2466525_12 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000715 281.0
HKD3_k127_2466525_13 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001532 235.0
HKD3_k127_2466525_14 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000000225 207.0
HKD3_k127_2466525_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 580.0
HKD3_k127_2466525_3 HAMP domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 553.0
HKD3_k127_2466525_4 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 496.0
HKD3_k127_2466525_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 424.0
HKD3_k127_2466525_6 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 412.0
HKD3_k127_2466525_7 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 364.0
HKD3_k127_2466525_8 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 362.0
HKD3_k127_2466525_9 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 338.0
HKD3_k127_2478966_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 516.0
HKD3_k127_2478966_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 266.0
HKD3_k127_2478966_2 - - - - 0.00000000000002273 78.0
HKD3_k127_2478966_3 Domain of unknown function (DUF4136) - - - 0.000000007842 66.0
HKD3_k127_2489079_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.837e-315 987.0
HKD3_k127_2489079_1 2 heme-binding sites K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 519.0
HKD3_k127_2489079_2 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 349.0
HKD3_k127_2513173_0 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005902 269.0
HKD3_k127_2513173_1 chlorophyll binding - - - 0.0000000000000000000000000001437 127.0
HKD3_k127_2513173_2 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.00000000000000000000008933 110.0
HKD3_k127_2513700_0 Rod shape-determining protein K03569 - - 1.632e-200 632.0
HKD3_k127_2513700_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 564.0
HKD3_k127_2513700_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 525.0
HKD3_k127_2513700_3 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
HKD3_k127_2522404_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1138.0
HKD3_k127_2522404_1 ABC transporter K06147,K06148 - - 2.183e-297 922.0
HKD3_k127_2522404_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000287 260.0
HKD3_k127_2522404_11 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009907 267.0
HKD3_k127_2522404_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000001163 219.0
HKD3_k127_2522404_13 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000000004656 196.0
HKD3_k127_2522404_14 - - - - 0.0000000000000000000000000000000000000000837 154.0
HKD3_k127_2522404_15 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000226 146.0
HKD3_k127_2522404_2 Transglycosylase SLT domain K08309 - - 6.197e-215 690.0
HKD3_k127_2522404_3 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000979 486.0
HKD3_k127_2522404_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 496.0
HKD3_k127_2522404_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 464.0
HKD3_k127_2522404_6 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 366.0
HKD3_k127_2522404_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 366.0
HKD3_k127_2522404_8 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 326.0
HKD3_k127_2522404_9 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003667 280.0
HKD3_k127_2525023_0 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 632.0
HKD3_k127_2525023_1 Phosphate acyltransferases K00655,K15781 - 2.3.1.51,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 451.0
HKD3_k127_2525023_2 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000415 154.0
HKD3_k127_2525023_3 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000001214 92.0
HKD3_k127_2545827_0 Thioredoxin - - - 7.635e-249 785.0
HKD3_k127_2545827_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 404.0
HKD3_k127_2545827_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000006739 243.0
HKD3_k127_2545827_3 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001169 246.0
HKD3_k127_2545827_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000003843 132.0
HKD3_k127_255821_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1304.0
HKD3_k127_255821_1 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 1.221e-230 730.0
HKD3_k127_255821_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.412e-227 712.0
HKD3_k127_255821_3 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 598.0
HKD3_k127_255821_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 436.0
HKD3_k127_255821_5 protein import - - - 0.00000000000000000000000000000001219 139.0
HKD3_k127_2576899_0 Heat shock 70 kDa protein - - - 5.049e-258 819.0
HKD3_k127_2576899_1 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 316.0
HKD3_k127_2576899_2 Asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 306.0
HKD3_k127_2576899_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000003921 235.0
HKD3_k127_2576899_4 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000000009627 188.0
HKD3_k127_2576899_5 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000006985 139.0
HKD3_k127_2576899_6 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000008996 110.0
HKD3_k127_2576899_7 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000004736 121.0
HKD3_k127_2576899_8 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000002236 105.0
HKD3_k127_2600683_0 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 474.0
HKD3_k127_2600683_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002632 283.0
HKD3_k127_2600683_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001272 288.0
HKD3_k127_2600683_3 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000001152 208.0
HKD3_k127_2600683_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000008936 185.0
HKD3_k127_2610473_0 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 400.0
HKD3_k127_2610473_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000006286 181.0
HKD3_k127_2610473_2 - - - - 0.00000000000000000000000004793 114.0
HKD3_k127_2610473_3 - - - - 0.0000000000000000001155 103.0
HKD3_k127_2610473_4 PFAM polysaccharide deacetylase - - - 0.0000006916 61.0
HKD3_k127_2610473_5 CoA-substrate-specific enzyme activase - - - 0.00005047 47.0
HKD3_k127_2623216_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.053e-302 934.0
HKD3_k127_2623216_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 9.79e-222 709.0
HKD3_k127_2623216_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000001927 139.0
HKD3_k127_2623216_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 489.0
HKD3_k127_2623216_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 362.0
HKD3_k127_2623216_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 316.0
HKD3_k127_2623216_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 304.0
HKD3_k127_2623216_6 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000002437 228.0
HKD3_k127_2623216_7 Gaf domain K21009 - - 0.000000000000000000000000000000000000000000000000000001876 216.0
HKD3_k127_2623216_8 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000002921 184.0
HKD3_k127_2623216_9 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000003971 197.0
HKD3_k127_2625015_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 383.0
HKD3_k127_2625015_1 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
HKD3_k127_2625015_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 339.0
HKD3_k127_2625015_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 320.0
HKD3_k127_2625015_4 PFAM thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000001432 152.0
HKD3_k127_2625015_5 - - - - 0.0000000000000000000000000002931 122.0
HKD3_k127_2628737_0 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 3.104e-260 811.0
HKD3_k127_2628737_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.206e-217 696.0
HKD3_k127_2628737_10 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008941 287.0
HKD3_k127_2628737_11 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005508 288.0
HKD3_k127_2628737_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000007622 245.0
HKD3_k127_2628737_13 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000001061 213.0
HKD3_k127_2628737_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000001185 198.0
HKD3_k127_2628737_15 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000003152 166.0
HKD3_k127_2628737_16 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000001431 107.0
HKD3_k127_2628737_17 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000008036 101.0
HKD3_k127_2628737_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 613.0
HKD3_k127_2628737_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 551.0
HKD3_k127_2628737_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 506.0
HKD3_k127_2628737_5 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 404.0
HKD3_k127_2628737_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 358.0
HKD3_k127_2628737_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 364.0
HKD3_k127_2628737_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 348.0
HKD3_k127_2628737_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 307.0
HKD3_k127_2633496_0 Type III secretion protein K03230 - - 2.232e-212 706.0
HKD3_k127_2633496_1 DUF1704 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 388.0
HKD3_k127_2633496_2 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417,K03225 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000002704 252.0
HKD3_k127_2633496_3 type iii secretion K03226 - - 0.00000000000000000000000000000000000000000000000000000000000000000004122 243.0
HKD3_k127_2633496_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.0000000000000000000000000000000000000000000000000000000000000000000585 254.0
HKD3_k127_2633496_5 protein targeting K02421,K03228 - - 0.00000000000000000000000000000000000000000000000000000000000000706 229.0
HKD3_k127_2633496_6 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000000000000000000000000000000000000000007909 221.0
HKD3_k127_2633496_8 Flagellar biosynthetic protein FliQ K02420,K03227 - - 0.0000000000000000004907 90.0
HKD3_k127_2636218_0 HAMP domain K02482 - 2.7.13.3 1.226e-201 653.0
HKD3_k127_2636218_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 601.0
HKD3_k127_2636218_3 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000002572 96.0
HKD3_k127_2670_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.69e-255 813.0
HKD3_k127_2670_1 chaperone-mediated protein folding K21007 - - 2.413e-205 663.0
HKD3_k127_2670_2 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 491.0
HKD3_k127_2670_3 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 365.0
HKD3_k127_2670_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000006905 155.0
HKD3_k127_2670_6 OmpW family K07275 - - 0.0000000000000142 82.0
HKD3_k127_2670_7 Domain of unknown function (DUF4136) - - - 0.00000000001309 74.0
HKD3_k127_2676047_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 584.0
HKD3_k127_2676047_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 535.0
HKD3_k127_2676047_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 357.0
HKD3_k127_2676047_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 369.0
HKD3_k127_2676047_4 PAP2 superfamily C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006557 265.0
HKD3_k127_2676047_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000003265 149.0
HKD3_k127_2676047_6 Outer membrane efflux protein - - - 0.00000000000000000002008 105.0
HKD3_k127_2676047_7 AcrB/AcrD/AcrF family - - - 0.000000001024 60.0
HKD3_k127_267827_0 WD40-like Beta Propeller Repeat - - - 2.889e-283 920.0
HKD3_k127_267827_1 Aminotransferase K00812 - 2.6.1.1 2.558e-199 628.0
HKD3_k127_267827_10 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 289.0
HKD3_k127_267827_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 284.0
HKD3_k127_267827_12 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000004588 244.0
HKD3_k127_267827_13 Allophanate hydrolase subunit 1 K06351 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005547 250.0
HKD3_k127_267827_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001077 266.0
HKD3_k127_267827_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
HKD3_k127_267827_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005755 227.0
HKD3_k127_267827_19 Domain of unknown function (DUF4382) - - - 0.000116 53.0
HKD3_k127_267827_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 556.0
HKD3_k127_267827_3 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 475.0
HKD3_k127_267827_4 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 398.0
HKD3_k127_267827_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 394.0
HKD3_k127_267827_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 380.0
HKD3_k127_267827_7 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 363.0
HKD3_k127_267827_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 335.0
HKD3_k127_267827_9 TIGRFAM urea amidolyase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 332.0
HKD3_k127_2688549_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.339e-196 620.0
HKD3_k127_2688549_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 341.0
HKD3_k127_2688549_3 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
HKD3_k127_2688549_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000006015 188.0
HKD3_k127_2714706_0 PFAM Alpha amylase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 466.0
HKD3_k127_2714706_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 367.0
HKD3_k127_2714706_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001738 277.0
HKD3_k127_2714706_3 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000003126 227.0
HKD3_k127_2714706_4 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000005345 229.0
HKD3_k127_2714706_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000003889 149.0
HKD3_k127_2714706_7 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.000000000000000000000000000000000001491 147.0
HKD3_k127_2714706_8 Domain of unknown function (DUF4198) K10094 - - 0.000000000000000000001664 103.0
HKD3_k127_2725109_0 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 446.0
HKD3_k127_2725109_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 379.0
HKD3_k127_2725109_2 branched-chain amino acid K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 362.0
HKD3_k127_2725109_3 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 364.0
HKD3_k127_2725109_4 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000001367 200.0
HKD3_k127_2725109_5 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000003598 78.0
HKD3_k127_2727019_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 515.0
HKD3_k127_2727019_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 260.0
HKD3_k127_2727019_2 chaperone-mediated protein complex assembly - - - 0.00000000000000000000001094 111.0
HKD3_k127_2727019_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000001326 89.0
HKD3_k127_2727019_4 chaperone-mediated protein complex assembly - - - 0.00007811 55.0
HKD3_k127_2747580_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.898e-276 898.0
HKD3_k127_2747580_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.416e-224 702.0
HKD3_k127_2747580_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 595.0
HKD3_k127_2747580_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 471.0
HKD3_k127_2747580_4 Dyp-type peroxidase family K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 310.0
HKD3_k127_2747580_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000348 265.0
HKD3_k127_2747580_6 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000006061 205.0
HKD3_k127_2758745_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.456e-277 861.0
HKD3_k127_2758745_1 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 588.0
HKD3_k127_2758745_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 509.0
HKD3_k127_2758745_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003529 257.0
HKD3_k127_2758745_4 PFAM response regulator receiver K11384 - - 0.00000000000000002839 82.0
HKD3_k127_2817405_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1204.0
HKD3_k127_2817405_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1099.0
HKD3_k127_2817405_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 5.377e-300 940.0
HKD3_k127_2817405_3 pfam abc1 K03688 - - 7.703e-235 741.0
HKD3_k127_2817405_5 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 400.0
HKD3_k127_2817405_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 395.0
HKD3_k127_2817405_9 PFAM UspA - - - 0.00000000000000000002869 108.0
HKD3_k127_2876591_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 3.576e-273 860.0
HKD3_k127_2876591_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 379.0
HKD3_k127_2876591_2 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 389.0
HKD3_k127_2876591_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005231 244.0
HKD3_k127_2876591_4 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000006446 234.0
HKD3_k127_2876591_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000005585 204.0
HKD3_k127_2876591_6 lipopolysaccharide transport K09774 - - 0.000000000000000000000000000001172 135.0
HKD3_k127_2885697_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 5.05e-205 642.0
HKD3_k127_2885697_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 601.0
HKD3_k127_2885697_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
HKD3_k127_2885697_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 314.0
HKD3_k127_2885697_4 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000006071 194.0
HKD3_k127_2909227_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 5e-324 1032.0
HKD3_k127_2909227_1 Tetratricopeptide repeats - - - 8.245e-245 784.0
HKD3_k127_2909227_2 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 6.564e-242 752.0
HKD3_k127_2909227_3 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 507.0
HKD3_k127_2909227_4 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 449.0
HKD3_k127_2909227_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 361.0
HKD3_k127_2909227_6 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000001416 183.0
HKD3_k127_2909227_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000001509 183.0
HKD3_k127_2915527_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 306.0
HKD3_k127_2915527_1 response regulator K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000008543 251.0
HKD3_k127_2915527_3 Glutaredoxin K03676 - - 0.00000000000000002698 82.0
HKD3_k127_2922095_0 Cytochrome c554 and c-prime - - - 2.265e-220 707.0
HKD3_k127_2922095_1 Beta-Casp domain K07576 - - 3.304e-209 659.0
HKD3_k127_2922095_10 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000001854 241.0
HKD3_k127_2922095_11 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001958 257.0
HKD3_k127_2922095_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000008622 242.0
HKD3_k127_2922095_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000004793 212.0
HKD3_k127_2922095_16 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000000000000000001599 161.0
HKD3_k127_2922095_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.285e-197 621.0
HKD3_k127_2922095_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 576.0
HKD3_k127_2922095_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 484.0
HKD3_k127_2922095_5 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
HKD3_k127_2922095_6 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 355.0
HKD3_k127_2922095_7 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 340.0
HKD3_k127_2922095_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
HKD3_k127_2922095_9 dimethylhistidine N-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001266 261.0
HKD3_k127_2926606_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 3.486e-253 790.0
HKD3_k127_2926606_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.326e-227 717.0
HKD3_k127_2926606_2 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 565.0
HKD3_k127_2926606_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 539.0
HKD3_k127_2926606_4 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 304.0
HKD3_k127_2926606_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006299 241.0
HKD3_k127_2926606_6 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000001119 149.0
HKD3_k127_2926606_7 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.00000000000000000000005762 112.0
HKD3_k127_2926606_8 Protein of unknown function (DUF2905) - - - 0.00000000000000000001407 92.0
HKD3_k127_2969315_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1310.0
HKD3_k127_2969315_1 Fad linked oxidase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 538.0
HKD3_k127_2969315_2 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 483.0
HKD3_k127_2969315_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
HKD3_k127_2969315_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
HKD3_k127_2969315_5 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 340.0
HKD3_k127_2969315_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 288.0
HKD3_k127_2969315_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000003689 143.0
HKD3_k127_2972261_0 AAA domain K10742 - 3.6.4.12 3.528e-289 899.0
HKD3_k127_2972261_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 428.0
HKD3_k127_2972261_2 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 367.0
HKD3_k127_2972261_3 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000002061 168.0
HKD3_k127_2972261_4 arsenate reductase K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000007069 119.0
HKD3_k127_2972261_5 - - - - 0.00000000000000007621 83.0
HKD3_k127_2972261_6 Smr domain - - - 0.00006293 55.0
HKD3_k127_3026056_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 501.0
HKD3_k127_3026056_1 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 428.0
HKD3_k127_3026056_10 Biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000003895 177.0
HKD3_k127_3026056_11 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000001014 186.0
HKD3_k127_3026056_12 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000001563 155.0
HKD3_k127_3026056_2 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 408.0
HKD3_k127_3026056_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 304.0
HKD3_k127_3026056_4 Dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004912 279.0
HKD3_k127_3026056_5 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000002457 255.0
HKD3_k127_3026056_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000007411 220.0
HKD3_k127_3026056_7 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000000004984 200.0
HKD3_k127_3026056_8 gamma-glutamylcyclotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000309 200.0
HKD3_k127_3026056_9 Protein of unknown function (DUF423) - - - 0.0000000000000000000000000000000000000000000000003447 178.0
HKD3_k127_3032508_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 2.034e-201 651.0
HKD3_k127_3032508_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 567.0
HKD3_k127_3032508_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 422.0
HKD3_k127_3032508_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 390.0
HKD3_k127_3032508_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 299.0
HKD3_k127_3032508_5 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000000000000000000006688 171.0
HKD3_k127_3088333_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.305e-237 745.0
HKD3_k127_3088333_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 573.0
HKD3_k127_3088333_10 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005812 273.0
HKD3_k127_3088333_13 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000002884 180.0
HKD3_k127_3088333_14 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000002542 142.0
HKD3_k127_3088333_15 Redoxin K03564 - 1.11.1.15 0.00000000000000000003173 102.0
HKD3_k127_3088333_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009386 499.0
HKD3_k127_3088333_3 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 494.0
HKD3_k127_3088333_4 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 482.0
HKD3_k127_3088333_5 domain protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 477.0
HKD3_k127_3088333_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 372.0
HKD3_k127_3088333_7 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 358.0
HKD3_k127_3088333_8 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 345.0
HKD3_k127_3088333_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 347.0
HKD3_k127_309550_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 576.0
HKD3_k127_309550_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 483.0
HKD3_k127_309550_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 410.0
HKD3_k127_309550_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 346.0
HKD3_k127_3134099_0 UvrD/REP helicase N-terminal domain - - - 7.93e-276 870.0
HKD3_k127_3134099_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 527.0
HKD3_k127_3134099_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004077 277.0
HKD3_k127_3134099_3 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000000000000000000000000002472 205.0
HKD3_k127_3134099_4 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000003187 179.0
HKD3_k127_3134099_5 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000000000000000000000000000004454 157.0
HKD3_k127_3134099_6 - - - - 0.00000000000000000000000000000003572 140.0
HKD3_k127_3134099_7 Haem-degrading - - - 0.00000000000000000000000000000008394 135.0
HKD3_k127_3134099_8 hydratase decarboxylase - - - 0.000000000000000000000002348 102.0
HKD3_k127_31399_0 UDP binding domain K00012 - 1.1.1.22 1.592e-206 649.0
HKD3_k127_31399_1 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003461 277.0
HKD3_k127_31399_2 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000001505 129.0
HKD3_k127_3208862_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 4.041e-195 612.0
HKD3_k127_3208862_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 535.0
HKD3_k127_3208862_10 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000000001869 135.0
HKD3_k127_3208862_11 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002471 147.0
HKD3_k127_3208862_12 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001708 70.0
HKD3_k127_3208862_2 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 479.0
HKD3_k127_3208862_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 400.0
HKD3_k127_3208862_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 382.0
HKD3_k127_3208862_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009843 266.0
HKD3_k127_3208862_6 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000004299 195.0
HKD3_k127_3208862_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000003318 203.0
HKD3_k127_3208862_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005171 183.0
HKD3_k127_3208862_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000003899 152.0
HKD3_k127_327223_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 572.0
HKD3_k127_327223_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 430.0
HKD3_k127_327223_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 353.0
HKD3_k127_327223_3 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009589 252.0
HKD3_k127_3286958_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 593.0
HKD3_k127_3286958_1 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 389.0
HKD3_k127_3286958_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 406.0
HKD3_k127_3286958_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 300.0
HKD3_k127_3286958_4 R3H domain K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001869 250.0
HKD3_k127_3286958_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000008731 130.0
HKD3_k127_3286958_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000007976 116.0
HKD3_k127_3286958_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001337 122.0
HKD3_k127_3286958_8 Polymer-forming cytoskeletal - - - 0.0000000000000000001416 103.0
HKD3_k127_3286958_9 Ribosomal protein L34 K02914 - - 0.00000000000004475 73.0
HKD3_k127_3307177_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.155e-262 820.0
HKD3_k127_3307177_1 CBS domain containing protein K07182 - - 6.698e-261 816.0
HKD3_k127_3307177_2 CBS domain containing protein K07182 - - 1.465e-252 793.0
HKD3_k127_3307177_3 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 437.0
HKD3_k127_3307177_4 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
HKD3_k127_3307177_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000002766 270.0
HKD3_k127_3307177_6 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000003463 203.0
HKD3_k127_3307177_7 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000001006 115.0
HKD3_k127_334180_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 1.513e-195 615.0
HKD3_k127_334180_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000002951 170.0
HKD3_k127_3473833_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 2.805e-311 965.0
HKD3_k127_3473833_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 9.456e-222 709.0
HKD3_k127_3473833_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 356.0
HKD3_k127_3473833_3 Ubiquinol-cytochrome C reductase - - - 0.000000000000000000000000000000000000000000000000009426 183.0
HKD3_k127_3473833_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.0000000000000000000182 108.0
HKD3_k127_3628212_0 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000003958 172.0
HKD3_k127_3628212_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000003316 169.0
HKD3_k127_3628212_2 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000005267 161.0
HKD3_k127_3628664_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0 1308.0
HKD3_k127_3628664_1 Tetratricopeptide repeat - - - 1.527e-302 1022.0
HKD3_k127_3628664_10 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 351.0
HKD3_k127_3628664_11 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 308.0
HKD3_k127_3628664_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000008309 259.0
HKD3_k127_3628664_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000001603 151.0
HKD3_k127_3628664_15 RDD family - - - 0.000000000000000000000000000000004123 143.0
HKD3_k127_3628664_2 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 8.557e-276 861.0
HKD3_k127_3628664_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 565.0
HKD3_k127_3628664_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 529.0
HKD3_k127_3628664_5 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 532.0
HKD3_k127_3628664_6 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 513.0
HKD3_k127_3628664_7 nuclear chromosome segregation K02557,K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 498.0
HKD3_k127_3628664_8 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 479.0
HKD3_k127_3628664_9 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 387.0
HKD3_k127_3649008_0 Putative glutamine amidotransferase - - - 2.031e-317 1007.0
HKD3_k127_3649008_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 6.561e-277 863.0
HKD3_k127_3649008_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 456.0
HKD3_k127_3649008_3 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 384.0
HKD3_k127_3653209_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 559.0
HKD3_k127_3653209_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 476.0
HKD3_k127_3653209_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 370.0
HKD3_k127_3653209_3 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 340.0
HKD3_k127_3653209_4 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002442 312.0
HKD3_k127_3653209_5 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007155 285.0
HKD3_k127_3653209_6 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004157 267.0
HKD3_k127_3664886_0 radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 598.0
HKD3_k127_3664886_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 467.0
HKD3_k127_3664886_2 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
HKD3_k127_3664886_3 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000002443 150.0
HKD3_k127_3664886_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000002472 126.0
HKD3_k127_3681767_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1660.0
HKD3_k127_3681767_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 5.452e-283 922.0
HKD3_k127_3681767_10 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 520.0
HKD3_k127_3681767_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 544.0
HKD3_k127_3681767_12 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 398.0
HKD3_k127_3681767_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 391.0
HKD3_k127_3681767_14 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 391.0
HKD3_k127_3681767_15 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 355.0
HKD3_k127_3681767_16 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 346.0
HKD3_k127_3681767_17 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 381.0
HKD3_k127_3681767_18 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 346.0
HKD3_k127_3681767_19 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 298.0
HKD3_k127_3681767_2 Type II and III secretion system protein K02453 - - 9.938e-268 850.0
HKD3_k127_3681767_20 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003643 279.0
HKD3_k127_3681767_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001705 284.0
HKD3_k127_3681767_22 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002325 282.0
HKD3_k127_3681767_23 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003432 237.0
HKD3_k127_3681767_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001324 230.0
HKD3_k127_3681767_25 TonB C terminal K03646,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000006851 226.0
HKD3_k127_3681767_26 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000000000000000000000000000000000000000000315 234.0
HKD3_k127_3681767_27 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000000000000000000000000005694 222.0
HKD3_k127_3681767_28 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000000000000000000000000000000000002076 200.0
HKD3_k127_3681767_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000003245 197.0
HKD3_k127_3681767_3 Glycosyl transferase family 21 - - - 8.414e-236 740.0
HKD3_k127_3681767_30 general secretion pathway protein K02456,K02457,K02459,K10927,K12285 - - 0.000000000000000000000000000000000000000000000000004584 187.0
HKD3_k127_3681767_31 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000000000000000000000000000000001737 190.0
HKD3_k127_3681767_32 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000001525 165.0
HKD3_k127_3681767_33 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000004175 133.0
HKD3_k127_3681767_34 Bacterial Ig-like domain 2 - - - 0.0000000001117 73.0
HKD3_k127_3681767_4 Surface antigen - - - 3.7e-234 762.0
HKD3_k127_3681767_5 response regulator K07713 - - 1.408e-224 707.0
HKD3_k127_3681767_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 592.0
HKD3_k127_3681767_7 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 587.0
HKD3_k127_3681767_8 PFAM chemotaxis sensory transducer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 594.0
HKD3_k127_3681767_9 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 563.0
HKD3_k127_3690033_0 SMART Elongator protein 3 MiaB NifB - - - 5.764e-238 743.0
HKD3_k127_3690033_1 Ribonuclease E/G family K08301 - - 1.433e-210 676.0
HKD3_k127_3690033_2 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 332.0
HKD3_k127_3690033_3 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000000000000000000000002808 188.0
HKD3_k127_3695178_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 5.137e-308 960.0
HKD3_k127_3695178_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 437.0
HKD3_k127_3695178_2 Sir2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 413.0
HKD3_k127_3695178_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
HKD3_k127_3695178_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008193 246.0
HKD3_k127_3695178_5 - - - - 0.000000000000000000000000000000000000000000000000000000000002292 215.0
HKD3_k127_3695178_6 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000001841 222.0
HKD3_k127_3695178_7 Putative inner membrane exporter, YdcZ K09936 - - 0.0000000000000000000000000000000000001908 145.0
HKD3_k127_3695178_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000001776 147.0
HKD3_k127_3701360_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 405.0
HKD3_k127_3730404_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.076e-302 949.0
HKD3_k127_3730404_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 4.87e-257 803.0
HKD3_k127_3730404_10 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000009879 220.0
HKD3_k127_3730404_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000003903 182.0
HKD3_k127_3730404_12 HD domain - - - 0.000000000000000000000000000000000000000001338 164.0
HKD3_k127_3730404_13 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000006421 139.0
HKD3_k127_3730404_14 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000004356 104.0
HKD3_k127_3730404_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000004534 67.0
HKD3_k127_3730404_18 regulation of single-species biofilm formation - - - 0.000000007753 67.0
HKD3_k127_3730404_19 - - - - 0.0001997 51.0
HKD3_k127_3730404_2 4Fe-4S binding domain - - - 3.08e-200 633.0
HKD3_k127_3730404_3 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 458.0
HKD3_k127_3730404_4 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 445.0
HKD3_k127_3730404_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 385.0
HKD3_k127_3730404_6 ABC transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 331.0
HKD3_k127_3730404_7 regulation of single-species biofilm formation K13572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001605 286.0
HKD3_k127_3730404_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000513 236.0
HKD3_k127_3730404_9 regulation of single-species biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000001037 237.0
HKD3_k127_3750003_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.729e-236 781.0
HKD3_k127_3750003_1 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 595.0
HKD3_k127_3750003_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 295.0
HKD3_k127_3750003_11 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008434 301.0
HKD3_k127_3750003_12 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000008847 234.0
HKD3_k127_3750003_13 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000001611 222.0
HKD3_k127_3750003_14 FMN binding - - - 0.000000000000000000000000000000000000000000000000000003275 196.0
HKD3_k127_3750003_15 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000002412 184.0
HKD3_k127_3750003_16 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.0000000000000000000000000000000000000417 161.0
HKD3_k127_3750003_17 4-Oxalocrotonate Tautomerase - - - 0.00000000000000000000000000000000000302 138.0
HKD3_k127_3750003_18 Bacterial PH domain - - - 0.00000000000000000000000000001495 130.0
HKD3_k127_3750003_2 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 534.0
HKD3_k127_3750003_20 EamA-like transporter family - - - 0.000000000000000154 94.0
HKD3_k127_3750003_22 Domain of unknown function (DUF4382) - - - 0.000000000005501 77.0
HKD3_k127_3750003_3 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 465.0
HKD3_k127_3750003_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 436.0
HKD3_k127_3750003_5 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 421.0
HKD3_k127_3750003_6 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 378.0
HKD3_k127_3750003_7 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 366.0
HKD3_k127_3750003_8 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 329.0
HKD3_k127_3750003_9 zinc metalloprotease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 316.0
HKD3_k127_3817789_0 heat shock protein 70 K04043 - - 1.562e-295 935.0
HKD3_k127_3817789_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.764e-276 876.0
HKD3_k127_3817789_10 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 354.0
HKD3_k127_3817789_11 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
HKD3_k127_3817789_12 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 308.0
HKD3_k127_3817789_13 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 287.0
HKD3_k127_3817789_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 287.0
HKD3_k127_3817789_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001091 272.0
HKD3_k127_3817789_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002254 261.0
HKD3_k127_3817789_17 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000003805 226.0
HKD3_k127_3817789_19 amine dehydrogenase activity K21449 - - 0.00000000000000000000000000000000000000000000000004931 183.0
HKD3_k127_3817789_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.52e-216 684.0
HKD3_k127_3817789_20 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000103 166.0
HKD3_k127_3817789_21 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000003801 147.0
HKD3_k127_3817789_23 zinc ion binding K06204 - - 0.00000000000000000000001068 112.0
HKD3_k127_3817789_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 4.078e-206 648.0
HKD3_k127_3817789_4 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 3.496e-196 623.0
HKD3_k127_3817789_5 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 518.0
HKD3_k127_3817789_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 481.0
HKD3_k127_3817789_7 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 454.0
HKD3_k127_3817789_8 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 451.0
HKD3_k127_3817789_9 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 406.0
HKD3_k127_3850433_0 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 472.0
HKD3_k127_3850433_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 310.0
HKD3_k127_3850433_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000006168 258.0
HKD3_k127_3850433_3 protein kinase activity - - - 0.00000000000000000000000000000000000000000000002107 190.0
HKD3_k127_3850433_4 Ferredoxin - - - 0.00000000000000000000000000000000000007253 144.0
HKD3_k127_3851345_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 5.858e-319 990.0
HKD3_k127_3851345_1 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 5.903e-223 708.0
HKD3_k127_3851345_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000007574 111.0
HKD3_k127_3851345_11 Ferredoxin - - - 0.000000000000000003547 97.0
HKD3_k127_3851345_12 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000002865 86.0
HKD3_k127_3851345_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 625.0
HKD3_k127_3851345_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 422.0
HKD3_k127_3851345_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 362.0
HKD3_k127_3851345_5 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009065 255.0
HKD3_k127_3851345_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005435 240.0
HKD3_k127_3851345_7 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000008867 201.0
HKD3_k127_3851345_8 - - - - 0.0000000000000000000000000000000000000000000002702 171.0
HKD3_k127_3851345_9 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000002757 188.0
HKD3_k127_3853591_0 Molydopterin dinucleotide binding domain - - - 5.327e-227 715.0
HKD3_k127_3853591_1 PKD domain - - - 0.000000000004988 79.0
HKD3_k127_3861160_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 501.0
HKD3_k127_3861160_1 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 401.0
HKD3_k127_3861160_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 357.0
HKD3_k127_3861160_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 306.0
HKD3_k127_3861160_4 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008691 301.0
HKD3_k127_3875697_0 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 536.0
HKD3_k127_3875697_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 466.0
HKD3_k127_3875697_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000004581 260.0
HKD3_k127_3875697_11 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000409 193.0
HKD3_k127_3875697_12 - - - - 0.000000000000000000000000000000002376 137.0
HKD3_k127_3875697_2 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 452.0
HKD3_k127_3875697_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 385.0
HKD3_k127_3875697_4 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 370.0
HKD3_k127_3875697_5 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 339.0
HKD3_k127_3875697_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 327.0
HKD3_k127_3875697_7 chlorophyll binding K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001407 304.0
HKD3_k127_3875697_8 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000302 293.0
HKD3_k127_3875697_9 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 261.0
HKD3_k127_3929121_0 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 312.0
HKD3_k127_3929121_1 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 314.0
HKD3_k127_3929121_2 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000001886 202.0
HKD3_k127_3929121_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000182 59.0
HKD3_k127_3948727_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 3.838e-199 625.0
HKD3_k127_3948727_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 543.0
HKD3_k127_3948727_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 331.0
HKD3_k127_3948727_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 309.0
HKD3_k127_3948727_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 287.0
HKD3_k127_3948727_5 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006629 278.0
HKD3_k127_3948727_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000007253 186.0
HKD3_k127_3948727_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000002391 164.0
HKD3_k127_3992_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.861e-294 921.0
HKD3_k127_3992_1 Multicopper oxidase K06324 - 1.16.3.3 6.428e-229 731.0
HKD3_k127_3992_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 304.0
HKD3_k127_4001562_0 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 373.0
HKD3_k127_4001562_1 Regulatory protein, FmdB family - - - 0.000000000000000000000000001436 115.0
HKD3_k127_4001562_2 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000001937 89.0
HKD3_k127_4013153_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 533.0
HKD3_k127_4013153_1 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000001109 204.0
HKD3_k127_4013153_2 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.000000000000000000002944 94.0
HKD3_k127_4013153_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000002475 83.0
HKD3_k127_4041303_0 Peptidase family M50 K11749 - - 1.044e-231 737.0
HKD3_k127_4041303_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 1.965e-204 642.0
HKD3_k127_4041303_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 388.0
HKD3_k127_4041303_11 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 378.0
HKD3_k127_4041303_12 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 360.0
HKD3_k127_4041303_13 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 353.0
HKD3_k127_4041303_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 319.0
HKD3_k127_4041303_15 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 317.0
HKD3_k127_4041303_16 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 296.0
HKD3_k127_4041303_17 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
HKD3_k127_4041303_18 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003091 297.0
HKD3_k127_4041303_19 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008209 299.0
HKD3_k127_4041303_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 548.0
HKD3_k127_4041303_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000649 272.0
HKD3_k127_4041303_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000007703 197.0
HKD3_k127_4041303_23 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000001219 176.0
HKD3_k127_4041303_24 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000005762 192.0
HKD3_k127_4041303_25 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000000009743 164.0
HKD3_k127_4041303_27 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000004258 144.0
HKD3_k127_4041303_3 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 553.0
HKD3_k127_4041303_30 Domain of unknown function (DUF4340) - - - 0.0000009362 62.0
HKD3_k127_4041303_31 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0001409 46.0
HKD3_k127_4041303_4 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 536.0
HKD3_k127_4041303_5 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 537.0
HKD3_k127_4041303_6 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 495.0
HKD3_k127_4041303_7 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 414.0
HKD3_k127_4041303_8 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
HKD3_k127_4041303_9 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 391.0
HKD3_k127_40591_0 regulation of single-species biofilm formation K13572,K13573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 490.0
HKD3_k127_40591_1 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 485.0
HKD3_k127_40591_2 Protein of unknown function (DUF1054) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HKD3_k127_40591_3 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
HKD3_k127_40591_4 Response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000000007562 161.0
HKD3_k127_4060426_0 4Fe-4S dicluster domain K18930 - - 0.0 1244.0
HKD3_k127_4060426_1 cluster binding protein K18929 - - 2.57e-204 657.0
HKD3_k127_4060426_2 COG0247 Fe-S K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 348.0
HKD3_k127_4060426_3 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007254 274.0
HKD3_k127_4060426_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000006548 223.0
HKD3_k127_4060426_5 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000001981 198.0
HKD3_k127_4060426_6 Thiamine-binding protein - - - 0.0000000000000000000000000000000000000000006436 157.0
HKD3_k127_4114596_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1254.0
HKD3_k127_4114596_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 509.0
HKD3_k127_4114596_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000001491 194.0
HKD3_k127_4114596_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000004537 173.0
HKD3_k127_4114596_4 fibroblast growth factor binding K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.000000000000000529 91.0
HKD3_k127_4128353_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1073.0
HKD3_k127_4128353_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 5.101e-289 906.0
HKD3_k127_4128353_10 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 458.0
HKD3_k127_4128353_11 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 438.0
HKD3_k127_4128353_12 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 442.0
HKD3_k127_4128353_13 Phosphoserine phosphatase K15781,K21830 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 416.0
HKD3_k127_4128353_14 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 391.0
HKD3_k127_4128353_15 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 383.0
HKD3_k127_4128353_16 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 358.0
HKD3_k127_4128353_17 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 376.0
HKD3_k127_4128353_18 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 333.0
HKD3_k127_4128353_19 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
HKD3_k127_4128353_2 response regulator K02481,K07713 - - 6.584e-264 839.0
HKD3_k127_4128353_20 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
HKD3_k127_4128353_21 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001259 259.0
HKD3_k127_4128353_22 PFAM DivIVA family protein K04074 - - 0.000000000000000000000000000000000000000000000000000000000000000001643 231.0
HKD3_k127_4128353_23 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000000000000000000000000000000000000213 205.0
HKD3_k127_4128353_24 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000001393 190.0
HKD3_k127_4128353_25 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.000000000000000000000000000000000000000000000002238 193.0
HKD3_k127_4128353_26 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000004659 153.0
HKD3_k127_4128353_27 zinc ion binding K06204 - - 0.00000000000000000000000000000003071 131.0
HKD3_k127_4128353_28 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.00000000000000000000003286 106.0
HKD3_k127_4128353_29 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.000000000000008256 79.0
HKD3_k127_4128353_3 Sigma-54 interaction domain - - - 2.586e-247 773.0
HKD3_k127_4128353_30 mttA/Hcf106 family K03116 - - 0.00000000000005675 74.0
HKD3_k127_4128353_4 Bacterial protein of unknown function (DUF853) - - - 8.561e-201 675.0
HKD3_k127_4128353_5 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 4.881e-195 622.0
HKD3_k127_4128353_6 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 603.0
HKD3_k127_4128353_7 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 537.0
HKD3_k127_4128353_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 523.0
HKD3_k127_4128353_9 Protoglobin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 499.0
HKD3_k127_4131139_0 Diguanylate cyclase, GGDEF domain - - - 0.0 1238.0
HKD3_k127_4131139_1 GTP-binding protein K06207 - - 0.0 1117.0
HKD3_k127_4131139_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 407.0
HKD3_k127_4131139_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 346.0
HKD3_k127_4131139_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000001933 211.0
HKD3_k127_4131139_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001488 201.0
HKD3_k127_4131139_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000001747 164.0
HKD3_k127_4131139_7 PhoQ Sensor - - - 0.00000000000000000000000000001367 124.0
HKD3_k127_41812_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1199.0
HKD3_k127_41812_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 6.951e-306 985.0
HKD3_k127_41812_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.93e-230 747.0
HKD3_k127_41812_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 469.0
HKD3_k127_41812_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 332.0
HKD3_k127_41812_5 - - - - 0.0000000609 65.0
HKD3_k127_422920_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 621.0
HKD3_k127_422920_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 485.0
HKD3_k127_422920_10 Protein of unknown function (DUF533) K11962 - - 0.00000000000000000000000000000000000000000000000000000000000001919 225.0
HKD3_k127_422920_11 - - - - 0.00000000000000000000000000000000000000000000000000000000002735 229.0
HKD3_k127_422920_12 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000001815 196.0
HKD3_k127_422920_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000002578 132.0
HKD3_k127_422920_14 Belongs to the ompA family K03286 - - 0.00000000000000000001036 109.0
HKD3_k127_422920_15 OmpA family K03286 - - 0.000000000000000005936 100.0
HKD3_k127_422920_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 415.0
HKD3_k127_422920_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
HKD3_k127_422920_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 353.0
HKD3_k127_422920_6 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 341.0
HKD3_k127_422920_7 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 302.0
HKD3_k127_422920_8 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002167 271.0
HKD3_k127_422920_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HKD3_k127_4246703_0 acyl-CoA dehydrogenase - - - 2.086e-249 793.0
HKD3_k127_4246703_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 657.0
HKD3_k127_4246703_10 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002365 273.0
HKD3_k127_4246703_11 OsmC-like protein - - - 0.000000000000000000000000000000000000000000002719 171.0
HKD3_k127_4246703_12 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000007694 140.0
HKD3_k127_4246703_13 Universal stress protein - - - 0.000000000000000000000000000001561 136.0
HKD3_k127_4246703_14 Tetratricopeptide repeat - - - 0.0000000000000000000007802 114.0
HKD3_k127_4246703_16 - - - - 0.00000000000000007083 90.0
HKD3_k127_4246703_18 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000001277 56.0
HKD3_k127_4246703_19 tetratricopeptide repeat protein - - - 0.00002913 59.0
HKD3_k127_4246703_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 606.0
HKD3_k127_4246703_3 Transporter, DASS family K11106,K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 565.0
HKD3_k127_4246703_4 anaerobic c4-dicarboxylate K07791,K07792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 421.0
HKD3_k127_4246703_5 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 406.0
HKD3_k127_4246703_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 377.0
HKD3_k127_4246703_7 LssY C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 348.0
HKD3_k127_4246703_8 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 343.0
HKD3_k127_4246703_9 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 353.0
HKD3_k127_426638_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.709e-278 865.0
HKD3_k127_426638_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 1.019e-240 749.0
HKD3_k127_426638_10 PFAM ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 377.0
HKD3_k127_426638_11 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 325.0
HKD3_k127_426638_12 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 316.0
HKD3_k127_426638_13 PTS system K02795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001435 262.0
HKD3_k127_426638_14 FtsZ-dependent cytokinesis K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003454 249.0
HKD3_k127_426638_15 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000007559 200.0
HKD3_k127_426638_16 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000003011 217.0
HKD3_k127_426638_17 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000003514 205.0
HKD3_k127_426638_18 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000009014 194.0
HKD3_k127_426638_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.459e-223 695.0
HKD3_k127_426638_20 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000000000001086 139.0
HKD3_k127_426638_21 Bacterial membrane protein, YfhO - - - 0.000000000000000000000007 120.0
HKD3_k127_426638_22 - - - - 0.000004196 52.0
HKD3_k127_426638_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 576.0
HKD3_k127_426638_4 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 566.0
HKD3_k127_426638_5 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 567.0
HKD3_k127_426638_6 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 475.0
HKD3_k127_426638_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 454.0
HKD3_k127_426638_8 phosphatidylinositol metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 409.0
HKD3_k127_426638_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 397.0
HKD3_k127_4316608_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1222.0
HKD3_k127_4316608_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 498.0
HKD3_k127_4316608_2 phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 499.0
HKD3_k127_4316608_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 456.0
HKD3_k127_4316608_4 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000005418 255.0
HKD3_k127_4316608_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001773 153.0
HKD3_k127_4386865_0 PHP domain protein - - - 5.84e-269 860.0
HKD3_k127_4386865_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 7.398e-241 752.0
HKD3_k127_4386865_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008415 522.0
HKD3_k127_4386865_11 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 507.0
HKD3_k127_4386865_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 497.0
HKD3_k127_4386865_13 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 472.0
HKD3_k127_4386865_14 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
HKD3_k127_4386865_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
HKD3_k127_4386865_16 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 395.0
HKD3_k127_4386865_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 392.0
HKD3_k127_4386865_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 381.0
HKD3_k127_4386865_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 347.0
HKD3_k127_4386865_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.548e-227 711.0
HKD3_k127_4386865_20 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 342.0
HKD3_k127_4386865_21 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 336.0
HKD3_k127_4386865_22 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 339.0
HKD3_k127_4386865_23 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 318.0
HKD3_k127_4386865_24 membrane protein required for spore maturation in B.subtilis K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004509 262.0
HKD3_k127_4386865_25 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000004473 271.0
HKD3_k127_4386865_26 Nucleoside recognition K06373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009415 259.0
HKD3_k127_4386865_27 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000004571 239.0
HKD3_k127_4386865_28 Abhydrolase domain containing 18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002843 243.0
HKD3_k127_4386865_29 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000003449 229.0
HKD3_k127_4386865_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 3.241e-216 679.0
HKD3_k127_4386865_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006405 236.0
HKD3_k127_4386865_31 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000001599 245.0
HKD3_k127_4386865_32 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000001474 213.0
HKD3_k127_4386865_33 OsmC-like protein K09136 - - 0.0000000000000000000000000000000000000000000000000005236 188.0
HKD3_k127_4386865_36 TM2 domain - - - 0.00000000000000000000001266 110.0
HKD3_k127_4386865_38 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000001556 105.0
HKD3_k127_4386865_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 3.497e-212 677.0
HKD3_k127_4386865_40 Malate synthase K01638 - 2.3.3.9 0.000000007641 63.0
HKD3_k127_4386865_5 Pfam:DUF955 K07110 - - 1.941e-196 623.0
HKD3_k127_4386865_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 579.0
HKD3_k127_4386865_7 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 556.0
HKD3_k127_4386865_8 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 571.0
HKD3_k127_4386865_9 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 532.0
HKD3_k127_461483_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.32e-200 631.0
HKD3_k127_461483_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 427.0
HKD3_k127_461483_2 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 380.0
HKD3_k127_461483_3 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 380.0
HKD3_k127_461483_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
HKD3_k127_461483_5 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000004935 167.0
HKD3_k127_461483_6 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000002073 161.0
HKD3_k127_47155_0 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 506.0
HKD3_k127_47155_1 Glycoside hydrolase family 44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 374.0
HKD3_k127_47155_2 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 267.0
HKD3_k127_47155_3 lipopolysaccharide N-acetylmannosaminouronosyltransferase activity K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000003618 264.0
HKD3_k127_47155_4 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
HKD3_k127_47155_5 beta-lactamase activity K07126,K19292 - - 0.00000000000000000000000000001089 126.0
HKD3_k127_4843516_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000001867 238.0
HKD3_k127_4843516_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001552 180.0
HKD3_k127_4863364_0 response regulator K07714 - - 3.597e-212 666.0
HKD3_k127_4863364_1 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 603.0
HKD3_k127_4863364_2 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 559.0
HKD3_k127_4863364_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 392.0
HKD3_k127_4863364_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 353.0
HKD3_k127_4863364_5 Type II secretion system (T2SS), protein M subtype b K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000996 273.0
HKD3_k127_4863364_6 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000000000008465 222.0
HKD3_k127_4863364_7 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000000007058 208.0
HKD3_k127_4863364_8 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000001083 114.0
HKD3_k127_4864665_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1427.0
HKD3_k127_4864665_1 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 570.0
HKD3_k127_4864665_2 Cell division protein FtsI penicillin-binding protein 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 468.0
HKD3_k127_4864665_3 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 425.0
HKD3_k127_4864665_4 sulfur carrier activity - - - 0.000000000000000000000000000005575 122.0
HKD3_k127_4866844_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1193.0
HKD3_k127_4866844_1 Histone deacetylase domain - - - 2.676e-254 823.0
HKD3_k127_4866844_10 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 432.0
HKD3_k127_4866844_11 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 387.0
HKD3_k127_4866844_12 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 361.0
HKD3_k127_4866844_13 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 388.0
HKD3_k127_4866844_14 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
HKD3_k127_4866844_15 8 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 334.0
HKD3_k127_4866844_16 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008708 275.0
HKD3_k127_4866844_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002799 273.0
HKD3_k127_4866844_18 Glutathione S-transferase K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000002206 243.0
HKD3_k127_4866844_19 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000009572 238.0
HKD3_k127_4866844_2 Angiotensin-converting enzyme K01283 - 3.4.15.1 3.707e-250 793.0
HKD3_k127_4866844_20 Dienelactone hydrolase family K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000002704 233.0
HKD3_k127_4866844_21 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000006251 190.0
HKD3_k127_4866844_22 - - - - 0.000000000000000000000000000000000000000000000001918 177.0
HKD3_k127_4866844_23 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000008171 179.0
HKD3_k127_4866844_24 Methyltransferase domain - - - 0.0000000000000000000000000000000000000006425 162.0
HKD3_k127_4866844_25 - - - - 0.0000000000000000000000000000000198 137.0
HKD3_k127_4866844_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000007457 135.0
HKD3_k127_4866844_29 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000208 68.0
HKD3_k127_4866844_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 4.88e-227 737.0
HKD3_k127_4866844_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 534.0
HKD3_k127_4866844_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 498.0
HKD3_k127_4866844_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 475.0
HKD3_k127_4866844_7 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 457.0
HKD3_k127_4866844_8 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 443.0
HKD3_k127_4866844_9 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 429.0
HKD3_k127_4869260_0 Sulfatase K01130 - 3.1.6.1 0.0 1152.0
HKD3_k127_4869260_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 507.0
HKD3_k127_4869260_2 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 379.0
HKD3_k127_4869260_4 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000003924 181.0
HKD3_k127_4874165_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 5.526e-293 922.0
HKD3_k127_4874165_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 1.437e-195 646.0
HKD3_k127_4874165_10 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 396.0
HKD3_k127_4874165_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 370.0
HKD3_k127_4874165_12 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 342.0
HKD3_k127_4874165_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 316.0
HKD3_k127_4874165_14 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008867 255.0
HKD3_k127_4874165_15 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
HKD3_k127_4874165_16 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000008127 250.0
HKD3_k127_4874165_17 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
HKD3_k127_4874165_18 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000000002984 206.0
HKD3_k127_4874165_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000004259 188.0
HKD3_k127_4874165_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 473.0
HKD3_k127_4874165_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000001589 189.0
HKD3_k127_4874165_21 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000001218 159.0
HKD3_k127_4874165_23 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000003239 134.0
HKD3_k127_4874165_24 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000001309 117.0
HKD3_k127_4874165_25 - - - - 0.00000000000000000000806 95.0
HKD3_k127_4874165_3 PFAM ABC transporter K01990,K01992,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 438.0
HKD3_k127_4874165_4 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 437.0
HKD3_k127_4874165_5 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 439.0
HKD3_k127_4874165_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 428.0
HKD3_k127_4874165_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 432.0
HKD3_k127_4874165_8 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 412.0
HKD3_k127_4874165_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 406.0
HKD3_k127_4894995_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 9.824e-304 944.0
HKD3_k127_4894995_1 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 585.0
HKD3_k127_4894995_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 333.0
HKD3_k127_4894995_3 Papain cysteine protease family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
HKD3_k127_4894995_4 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000258 151.0
HKD3_k127_4894995_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000003811 63.0
HKD3_k127_4895000_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.074e-320 1005.0
HKD3_k127_4895000_1 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 568.0
HKD3_k127_4895000_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000001145 213.0
HKD3_k127_4895000_3 carbon dioxide binding K04653,K04654 - - 0.00000000000000000000000000000000004992 155.0
HKD3_k127_4895000_4 spore germination K03605 - - 0.00000000000001899 75.0
HKD3_k127_4895330_0 pseudouridine synthase activity K06176 - 5.4.99.27 2.633e-198 625.0
HKD3_k127_4895330_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 592.0
HKD3_k127_4895330_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 489.0
HKD3_k127_4895330_3 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 419.0
HKD3_k127_4895330_4 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 354.0
HKD3_k127_4895330_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000001118 224.0
HKD3_k127_4895330_6 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000002028 178.0
HKD3_k127_4895330_7 - - - - 0.00000000000000000000000000000000000000000008478 171.0
HKD3_k127_4900902_0 PrkA serine protein kinase C-terminal domain - - - 1.196e-320 1002.0
HKD3_k127_4900902_1 Heat shock 70 kDa protein K04043 - - 5.878e-236 745.0
HKD3_k127_4900902_10 Asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000003971 192.0
HKD3_k127_4900902_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.132e-205 654.0
HKD3_k127_4900902_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 573.0
HKD3_k127_4900902_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 498.0
HKD3_k127_4900902_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 334.0
HKD3_k127_4900902_6 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 287.0
HKD3_k127_4900902_8 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000006641 222.0
HKD3_k127_4938910_0 Protein tyrosine kinase K12132 - 2.7.11.1 2.59e-220 691.0
HKD3_k127_4938910_1 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 419.0
HKD3_k127_4938910_2 PFAM Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HKD3_k127_4938910_3 Protein of unknown function, DUF485 - - - 0.000000000000000002097 89.0
HKD3_k127_4942738_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1371.0
HKD3_k127_4942738_1 Peptidase dimerisation domain - - - 1.338e-209 674.0
HKD3_k127_4942738_10 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000000000000001611 239.0
HKD3_k127_4942738_11 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000006789 241.0
HKD3_k127_4942738_12 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000004499 194.0
HKD3_k127_4942738_13 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000000000000000000003905 154.0
HKD3_k127_4942738_14 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000001195 156.0
HKD3_k127_4942738_15 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000007929 131.0
HKD3_k127_4942738_16 SnoaL-like domain - - - 0.000000000000000000000000000002924 139.0
HKD3_k127_4942738_17 Cupin domain - - - 0.0000000000000000000000001791 123.0
HKD3_k127_4942738_2 Sodium/hydrogen exchanger family K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009295 543.0
HKD3_k127_4942738_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 502.0
HKD3_k127_4942738_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 464.0
HKD3_k127_4942738_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 455.0
HKD3_k127_4942738_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 297.0
HKD3_k127_4942738_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
HKD3_k127_4942738_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004834 271.0
HKD3_k127_4942738_9 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
HKD3_k127_4956684_0 AMP-binding enzyme K01897 - 6.2.1.3 1.379e-276 861.0
HKD3_k127_4956684_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000002971 240.0
HKD3_k127_4976428_0 CoA-substrate-specific enzyme activase - - - 0.0 1678.0
HKD3_k127_4976428_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 561.0
HKD3_k127_4976428_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 372.0
HKD3_k127_4980418_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 571.0
HKD3_k127_4980418_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
HKD3_k127_4980418_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 551.0
HKD3_k127_4980418_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 449.0
HKD3_k127_4980418_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 433.0
HKD3_k127_4980418_5 amino acid ABC transporter, ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002571 245.0
HKD3_k127_4980418_6 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000001145 145.0
HKD3_k127_4997934_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 554.0
HKD3_k127_4997934_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 302.0
HKD3_k127_4997934_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000001358 183.0
HKD3_k127_4997934_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001296 163.0
HKD3_k127_4997934_4 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000005541 147.0
HKD3_k127_4997934_6 protein transport across the cell outer membrane K08084 - - 0.000000001766 68.0
HKD3_k127_4999014_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.502e-250 784.0
HKD3_k127_4999014_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 343.0
HKD3_k127_4999014_2 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 309.0
HKD3_k127_50051_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1142.0
HKD3_k127_50051_1 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001236 252.0
HKD3_k127_50051_2 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000000000000001419 158.0
HKD3_k127_50051_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000001575 92.0
HKD3_k127_5007525_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 7.535e-307 947.0
HKD3_k127_5007525_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.459e-284 896.0
HKD3_k127_5007525_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 534.0
HKD3_k127_5007525_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 467.0
HKD3_k127_5007525_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 407.0
HKD3_k127_5007525_5 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 367.0
HKD3_k127_5007525_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
HKD3_k127_5007525_7 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002928 244.0
HKD3_k127_5007525_8 fumarate reductase) cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000000006844 216.0
HKD3_k127_5007525_9 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000007899 189.0
HKD3_k127_501494_0 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 445.0
HKD3_k127_501494_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 404.0
HKD3_k127_501494_2 amino acid ABC transporter, ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 413.0
HKD3_k127_501494_3 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 369.0
HKD3_k127_5035274_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.226e-249 791.0
HKD3_k127_5035274_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 517.0
HKD3_k127_5035274_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 424.0
HKD3_k127_5035274_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 335.0
HKD3_k127_5035274_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
HKD3_k127_5035274_5 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 282.0
HKD3_k127_5035274_6 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000001029 229.0
HKD3_k127_5035274_7 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000003528 119.0
HKD3_k127_5035274_8 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000001205 65.0
HKD3_k127_5038482_0 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 473.0
HKD3_k127_5038482_1 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000009754 204.0
HKD3_k127_5038482_3 Sterol carrier protein - - - 0.000000000003312 67.0
HKD3_k127_5038482_4 - - - - 0.00000000001467 74.0
HKD3_k127_5038482_5 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000009341 68.0
HKD3_k127_5039303_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 535.0
HKD3_k127_5039303_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 415.0
HKD3_k127_5039303_10 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000385 174.0
HKD3_k127_5039303_12 Methyltransferase FkbM domain - - - 0.0000000000000000005756 94.0
HKD3_k127_5039303_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000006216 70.0
HKD3_k127_5039303_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 373.0
HKD3_k127_5039303_3 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 364.0
HKD3_k127_5039303_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 327.0
HKD3_k127_5039303_5 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 306.0
HKD3_k127_5039303_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000298 267.0
HKD3_k127_5039303_7 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001589 233.0
HKD3_k127_5039303_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000006543 222.0
HKD3_k127_5039303_9 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000005874 217.0
HKD3_k127_5042740_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 569.0
HKD3_k127_5042740_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 469.0
HKD3_k127_5042740_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 359.0
HKD3_k127_5042740_3 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000396 285.0
HKD3_k127_5042740_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000003694 132.0
HKD3_k127_5056060_0 Binding-protein-dependent transport system inner membrane component K02050 - - 7.774e-250 781.0
HKD3_k127_5056060_1 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 629.0
HKD3_k127_5056060_2 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000005872 55.0
HKD3_k127_5066632_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.967e-308 967.0
HKD3_k127_5066632_1 PFAM Extracellular ligand-binding receptor K01999 - - 2.737e-196 618.0
HKD3_k127_5066632_10 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000297 202.0
HKD3_k127_5066632_11 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000000005719 181.0
HKD3_k127_5066632_12 AMP binding - GO:0008150,GO:0040007 - 0.0000000000000000000003048 104.0
HKD3_k127_5066632_13 sequence-specific DNA binding - - - 0.00000000000000000001352 104.0
HKD3_k127_5066632_15 ATP-grasp domain K01945 - 6.3.4.13 0.000000002076 58.0
HKD3_k127_5066632_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 600.0
HKD3_k127_5066632_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 544.0
HKD3_k127_5066632_4 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 486.0
HKD3_k127_5066632_5 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 439.0
HKD3_k127_5066632_6 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 391.0
HKD3_k127_5066632_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
HKD3_k127_5066632_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001652 285.0
HKD3_k127_5066632_9 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001043 261.0
HKD3_k127_5100292_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.1e-234 732.0
HKD3_k127_5100292_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 509.0
HKD3_k127_5100292_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 437.0
HKD3_k127_5100292_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 392.0
HKD3_k127_5100292_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 373.0
HKD3_k127_5100292_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000006892 146.0
HKD3_k127_5118060_0 DNA helicase K03657 - 3.6.4.12 0.0 1063.0
HKD3_k127_5118060_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.274e-247 776.0
HKD3_k127_5118060_10 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009087 254.0
HKD3_k127_5118060_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000001185 194.0
HKD3_k127_5118060_12 Histidine kinase K07710,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000001039 173.0
HKD3_k127_5118060_13 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000002605 155.0
HKD3_k127_5118060_2 lysine biosynthetic process via aminoadipic acid - - - 3.791e-232 747.0
HKD3_k127_5118060_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 8.299e-231 732.0
HKD3_k127_5118060_4 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 1.943e-229 722.0
HKD3_k127_5118060_5 Insulinase (Peptidase family M16) K07263 - - 1.17e-202 640.0
HKD3_k127_5118060_6 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 557.0
HKD3_k127_5118060_7 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 526.0
HKD3_k127_5118060_8 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 442.0
HKD3_k127_5118060_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 398.0
HKD3_k127_5122982_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.411e-301 928.0
HKD3_k127_5122982_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.127e-263 815.0
HKD3_k127_5122982_10 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000284 256.0
HKD3_k127_5122982_11 HemY protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
HKD3_k127_5122982_13 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000004568 210.0
HKD3_k127_5122982_14 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000001457 173.0
HKD3_k127_5122982_15 - - - - 0.000000000000000000000007572 116.0
HKD3_k127_5122982_2 Belongs to the heat shock protein 70 family K04043 - - 8.059e-232 742.0
HKD3_k127_5122982_3 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 6.814e-194 623.0
HKD3_k127_5122982_4 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 579.0
HKD3_k127_5122982_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 529.0
HKD3_k127_5122982_6 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
HKD3_k127_5122982_7 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 335.0
HKD3_k127_5122982_8 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 312.0
HKD3_k127_5122982_9 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008736 301.0
HKD3_k127_5125069_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 4.125e-294 930.0
HKD3_k127_5125069_1 General secretory system II, protein E domain protein K02652 - - 1.022e-238 751.0
HKD3_k127_5125069_13 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000000000000001108 124.0
HKD3_k127_5125069_14 twitching motility protein K02669 - - 0.00000000000001213 73.0
HKD3_k127_5125069_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 599.0
HKD3_k127_5125069_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 416.0
HKD3_k127_5125069_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 378.0
HKD3_k127_5125069_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000158 241.0
HKD3_k127_5125069_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000007621 227.0
HKD3_k127_5125069_7 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.00000000000000000000000000000000000000000000000000003528 194.0
HKD3_k127_5125069_8 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000479 185.0
HKD3_k127_5125069_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000003783 184.0
HKD3_k127_5131065_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 588.0
HKD3_k127_5131065_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 443.0
HKD3_k127_5131065_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 347.0
HKD3_k127_5131065_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 352.0
HKD3_k127_5131065_4 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 316.0
HKD3_k127_5131065_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000107 246.0
HKD3_k127_5131065_7 regulation of DNA repair K03565 - - 0.00000000000000000000000000000000000000001248 160.0
HKD3_k127_5131065_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000001864 121.0
HKD3_k127_5166307_0 daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 381.0
HKD3_k127_5166307_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 357.0
HKD3_k127_5166307_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 360.0
HKD3_k127_5166307_3 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000000000000000006122 195.0
HKD3_k127_5166307_4 Protein of unknown function (FYDLN_acid) - - - 0.00007437 47.0
HKD3_k127_5264418_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.739e-227 735.0
HKD3_k127_5264418_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.414e-210 667.0
HKD3_k127_5264418_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 524.0
HKD3_k127_5264418_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 501.0
HKD3_k127_5264418_4 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 319.0
HKD3_k127_5264418_5 hydrolase activity, acting on ester bonds K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 310.0
HKD3_k127_5264418_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000004898 234.0
HKD3_k127_5264418_7 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000008416 153.0
HKD3_k127_5282475_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.749e-268 833.0
HKD3_k127_5282475_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.823e-225 706.0
HKD3_k127_5282475_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 606.0
HKD3_k127_5282475_3 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009638 255.0
HKD3_k127_5282475_4 TonB C terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000001028 244.0
HKD3_k127_5282475_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000006419 205.0
HKD3_k127_5282475_6 - - - - 0.000000000000000000000000001735 122.0
HKD3_k127_5282475_7 - - - - 0.000000000000000000000000003739 130.0
HKD3_k127_5306172_0 Receptor family ligand binding region K01999 - - 7.582e-197 625.0
HKD3_k127_5306172_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 390.0
HKD3_k127_5306172_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 352.0
HKD3_k127_5306172_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 376.0
HKD3_k127_5306172_4 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 301.0
HKD3_k127_5306172_5 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005552 300.0
HKD3_k127_5306172_6 POT family K03305 - - 0.00000886 48.0
HKD3_k127_5334009_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 492.0
HKD3_k127_5334009_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 476.0
HKD3_k127_5334009_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 467.0
HKD3_k127_5334009_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 400.0
HKD3_k127_5334009_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 369.0
HKD3_k127_5334009_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000000000000000000008398 239.0
HKD3_k127_5334009_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000004491 111.0
HKD3_k127_5334009_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000001111 95.0
HKD3_k127_5342281_0 Outer membrane receptor - - - 7.699e-299 950.0
HKD3_k127_5342281_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 479.0
HKD3_k127_5342281_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 412.0
HKD3_k127_5342281_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 394.0
HKD3_k127_5342281_4 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 312.0
HKD3_k127_5342281_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001844 280.0
HKD3_k127_5342281_6 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000000000000158 190.0
HKD3_k127_5342281_7 CRS1_YhbY K07574 - - 0.000000000000000000000000000000000000000000003536 166.0
HKD3_k127_5342281_8 biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000001246 179.0
HKD3_k127_5342281_9 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000001726 160.0
HKD3_k127_5390756_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 5.114e-254 797.0
HKD3_k127_5390756_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 600.0
HKD3_k127_5390756_2 RNA polymerase recycling family C-terminal K03580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 545.0
HKD3_k127_5390756_3 PFAM peptidase M20 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 531.0
HKD3_k127_5390756_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 383.0
HKD3_k127_5445291_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.519e-296 919.0
HKD3_k127_5445291_1 FAD dependent oxidoreductase K07137 - - 4.328e-274 851.0
HKD3_k127_5445291_10 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.00000000000000000000000000000000000000001064 163.0
HKD3_k127_5445291_11 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000118 112.0
HKD3_k127_5445291_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.173e-212 665.0
HKD3_k127_5445291_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 589.0
HKD3_k127_5445291_4 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 439.0
HKD3_k127_5445291_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 399.0
HKD3_k127_5445291_6 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 379.0
HKD3_k127_5445291_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 373.0
HKD3_k127_5445291_8 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000008008 252.0
HKD3_k127_5445291_9 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000003083 192.0
HKD3_k127_5482674_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 440.0
HKD3_k127_5482674_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 420.0
HKD3_k127_5482674_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 310.0
HKD3_k127_5482674_3 PFAM PHP domain protein K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000005522 268.0
HKD3_k127_5482674_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000000000000000000009718 189.0
HKD3_k127_5482674_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000001377 101.0
HKD3_k127_5489412_0 Sulfatase K01130,K01133 - 3.1.6.1,3.1.6.6 1.013e-286 902.0
HKD3_k127_5489412_1 Iron-sulfur cluster-binding domain K06871 - - 1.936e-228 715.0
HKD3_k127_5489412_2 Serine aminopeptidase, S33 - - - 5.689e-204 645.0
HKD3_k127_5489412_3 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 477.0
HKD3_k127_5489412_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004096 253.0
HKD3_k127_5489412_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000169 230.0
HKD3_k127_5489412_6 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000000000001431 130.0
HKD3_k127_5495643_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1549.0
HKD3_k127_5495643_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1353.0
HKD3_k127_5495643_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000002247 285.0
HKD3_k127_5495643_11 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001823 250.0
HKD3_k127_5495643_12 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000001166 179.0
HKD3_k127_5495643_15 Heavy-metal resistance - - - 0.00000000004609 71.0
HKD3_k127_5495643_16 - - - - 0.0000005713 53.0
HKD3_k127_5495643_2 4Fe-4S dicluster domain - - - 0.0 1013.0
HKD3_k127_5495643_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 553.0
HKD3_k127_5495643_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 542.0
HKD3_k127_5495643_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 544.0
HKD3_k127_5495643_6 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 467.0
HKD3_k127_5495643_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 418.0
HKD3_k127_5495643_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 363.0
HKD3_k127_5508032_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 619.0
HKD3_k127_5508032_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 368.0
HKD3_k127_5508032_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002033 269.0
HKD3_k127_5508032_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005215 244.0
HKD3_k127_5508032_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006178 254.0
HKD3_k127_5508032_5 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000002805 237.0
HKD3_k127_5508032_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000006313 78.0
HKD3_k127_5508032_7 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000006132 53.0
HKD3_k127_5517131_0 DEAD DEAH box helicase - - - 0.0 1311.0
HKD3_k127_5517131_1 Cysteine-rich domain K00113 - 1.1.5.3 7.928e-230 722.0
HKD3_k127_5517131_2 Double sensory domain of two-component sensor kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 298.0
HKD3_k127_5517131_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
HKD3_k127_5517131_4 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001546 269.0
HKD3_k127_5517131_5 - - - - 0.00000000003003 72.0
HKD3_k127_5517131_6 - - - - 0.00007286 54.0
HKD3_k127_5518870_0 Alcohol dehydrogenase GroES domain protein K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 477.0
HKD3_k127_5518870_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 341.0
HKD3_k127_5518870_2 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000001401 134.0
HKD3_k127_5518870_3 Insulinase (Peptidase family M16) - - - 0.0000000001013 64.0
HKD3_k127_5566019_0 iron-sulfur binding K00184 - - 0.0 1109.0
HKD3_k127_5566019_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 9.267e-231 721.0
HKD3_k127_5566019_10 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000004193 197.0
HKD3_k127_5566019_2 Polysulphide reductase, NrfD K00185 - - 1.074e-207 698.0
HKD3_k127_5566019_3 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 486.0
HKD3_k127_5566019_4 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
HKD3_k127_5566019_5 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 353.0
HKD3_k127_5566019_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 357.0
HKD3_k127_5566019_7 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 354.0
HKD3_k127_5566019_8 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000001257 208.0
HKD3_k127_5566019_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000001158 212.0
HKD3_k127_5569200_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1631.0
HKD3_k127_5569200_1 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 608.0
HKD3_k127_5569200_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 595.0
HKD3_k127_5569200_3 spore germination K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 368.0
HKD3_k127_5569200_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 340.0
HKD3_k127_5569200_5 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000105 181.0
HKD3_k127_5569200_6 - - - - 0.00000000000000000000000000000000000001533 164.0
HKD3_k127_5569200_7 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000001197 153.0
HKD3_k127_5574893_0 Glycogen debranching enzyme - - - 0.0 1382.0
HKD3_k127_5574893_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 349.0
HKD3_k127_5574893_2 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 352.0
HKD3_k127_5574893_3 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000001562 153.0
HKD3_k127_5574893_4 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.00000000000000000000000000000001282 127.0
HKD3_k127_5654379_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 7.334e-236 761.0
HKD3_k127_5654379_1 DNA restriction-modification system - - - 9.093e-223 710.0
HKD3_k127_5654379_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
HKD3_k127_5654379_3 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000001709 219.0
HKD3_k127_5654379_4 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000003125 183.0
HKD3_k127_5654379_5 - - - - 0.00000000000000000000000000000142 132.0
HKD3_k127_5725705_0 Oligoendopeptidase f - - - 1.903e-264 831.0
HKD3_k127_5725705_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 601.0
HKD3_k127_5725705_2 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 482.0
HKD3_k127_5725705_3 Cys Met metabolism K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007379 271.0
HKD3_k127_5725705_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006302 263.0
HKD3_k127_5725705_5 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000579 61.0
HKD3_k127_5728742_0 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 574.0
HKD3_k127_5728742_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 476.0
HKD3_k127_5728742_2 amidohydrolase - - - 0.000000000000000000000000000000000000000000000001513 186.0
HKD3_k127_576891_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.81e-286 893.0
HKD3_k127_576891_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.977e-276 857.0
HKD3_k127_576891_10 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 404.0
HKD3_k127_576891_11 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
HKD3_k127_576891_12 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 377.0
HKD3_k127_576891_13 PFAM PHP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 354.0
HKD3_k127_576891_14 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 352.0
HKD3_k127_576891_15 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 306.0
HKD3_k127_576891_16 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 305.0
HKD3_k127_576891_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 256.0
HKD3_k127_576891_18 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008549 259.0
HKD3_k127_576891_19 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003187 238.0
HKD3_k127_576891_2 peptidase U62 modulator of DNA gyrase - - - 8.03e-249 782.0
HKD3_k127_576891_20 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
HKD3_k127_576891_21 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
HKD3_k127_576891_22 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000002333 228.0
HKD3_k127_576891_24 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000001026 207.0
HKD3_k127_576891_25 peptide catabolic process K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000003642 220.0
HKD3_k127_576891_27 pseudouridine synthase activity K06176 - 5.4.99.27 0.00000000000000004227 84.0
HKD3_k127_576891_28 cheY-homologous receiver domain - - - 0.0000000000000001906 94.0
HKD3_k127_576891_3 Belongs to the GARS family K01945 - 6.3.4.13 4.426e-199 631.0
HKD3_k127_576891_4 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 609.0
HKD3_k127_576891_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 569.0
HKD3_k127_576891_6 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 540.0
HKD3_k127_576891_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 533.0
HKD3_k127_576891_8 protein kinase activity K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 454.0
HKD3_k127_576891_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 421.0
HKD3_k127_59164_0 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 544.0
HKD3_k127_59164_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 412.0
HKD3_k127_59164_2 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 394.0
HKD3_k127_59164_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 381.0
HKD3_k127_59164_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 333.0
HKD3_k127_59164_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 316.0
HKD3_k127_59164_6 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 298.0
HKD3_k127_59164_7 - - - - 0.0000000000000000000000000000000000001903 160.0
HKD3_k127_5916803_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1481.0
HKD3_k127_5916803_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1463.0
HKD3_k127_5916803_10 HB1, ASXL, restriction endonuclease HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 561.0
HKD3_k127_5916803_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 532.0
HKD3_k127_5916803_12 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 542.0
HKD3_k127_5916803_13 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 525.0
HKD3_k127_5916803_14 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 522.0
HKD3_k127_5916803_15 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 531.0
HKD3_k127_5916803_16 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 518.0
HKD3_k127_5916803_17 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 525.0
HKD3_k127_5916803_18 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 482.0
HKD3_k127_5916803_19 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 431.0
HKD3_k127_5916803_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1050.0
HKD3_k127_5916803_20 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 428.0
HKD3_k127_5916803_21 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 400.0
HKD3_k127_5916803_22 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 327.0
HKD3_k127_5916803_23 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 293.0
HKD3_k127_5916803_24 - K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 284.0
HKD3_k127_5916803_25 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000007272 250.0
HKD3_k127_5916803_26 polysaccharide catabolic process K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000759 253.0
HKD3_k127_5916803_28 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000004536 246.0
HKD3_k127_5916803_29 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000000000000000000000000000254 215.0
HKD3_k127_5916803_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.746e-235 734.0
HKD3_k127_5916803_30 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000002287 208.0
HKD3_k127_5916803_31 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000002818 199.0
HKD3_k127_5916803_32 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000005238 195.0
HKD3_k127_5916803_33 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000005814 175.0
HKD3_k127_5916803_35 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.00000000000000000000162 106.0
HKD3_k127_5916803_36 PilZ domain - - - 0.00000000000000003367 91.0
HKD3_k127_5916803_37 Cupredoxin-like domain - - - 0.00000000004187 68.0
HKD3_k127_5916803_38 - - - - 0.0000003116 53.0
HKD3_k127_5916803_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.419e-232 726.0
HKD3_k127_5916803_5 homoserine dehydrogenase K00003 - 1.1.1.3 1.676e-218 695.0
HKD3_k127_5916803_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 1.043e-212 692.0
HKD3_k127_5916803_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.627e-208 653.0
HKD3_k127_5916803_8 Transporter associated domain K03699 - - 8.265e-195 617.0
HKD3_k127_5916803_9 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 623.0
HKD3_k127_6004828_0 SpoVR like protein K06415 - - 2.579e-277 870.0
HKD3_k127_6004828_1 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 474.0
HKD3_k127_6004828_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 486.0
HKD3_k127_6048254_0 Aldehyde dehydrogenase family K00129 - 1.2.1.5 9.333e-224 722.0
HKD3_k127_6048254_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
HKD3_k127_6048254_2 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000007736 224.0
HKD3_k127_6048254_3 sequence-specific DNA binding - - - 0.0000000000000000000007248 94.0
HKD3_k127_6050184_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1398.0
HKD3_k127_6050184_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 486.0
HKD3_k127_6050184_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
HKD3_k127_6050184_3 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000002155 110.0
HKD3_k127_6055606_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 473.0
HKD3_k127_6055606_1 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 321.0
HKD3_k127_6055606_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003181 267.0
HKD3_k127_6055606_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000904 208.0
HKD3_k127_6055606_4 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000003147 169.0
HKD3_k127_6055606_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000001513 163.0
HKD3_k127_6055606_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000005785 90.0
HKD3_k127_6073548_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.552e-257 805.0
HKD3_k127_6073548_1 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002245 261.0
HKD3_k127_6073548_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 259.0
HKD3_k127_6073548_6 - - - - 0.00000000000005262 82.0
HKD3_k127_6073548_7 Lecithin retinol acyltransferase - - - 0.00000000001208 73.0
HKD3_k127_6073548_8 OsmC-like protein - - - 0.000000578 54.0
HKD3_k127_6090876_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1439.0
HKD3_k127_6090876_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 5.481e-218 683.0
HKD3_k127_6090876_2 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000001637 226.0
HKD3_k127_6090876_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000002118 93.0
HKD3_k127_6090876_5 Helix-turn-helix domain - - - 0.00000000000002527 78.0
HKD3_k127_6093451_0 Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 567.0
HKD3_k127_6093451_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 423.0
HKD3_k127_6093451_2 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
HKD3_k127_6093451_3 Sigma-70, region 4 - - - 0.00000000000000000000000000000000000000000000000000000000001016 214.0
HKD3_k127_6093451_4 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000001875 201.0
HKD3_k127_6093451_5 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000002707 119.0
HKD3_k127_6121244_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1060.0
HKD3_k127_6121244_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.205e-245 803.0
HKD3_k127_6121244_2 Response regulator, receiver K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 428.0
HKD3_k127_6121244_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 428.0
HKD3_k127_6121244_4 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 385.0
HKD3_k127_6121244_6 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002432 249.0
HKD3_k127_6121244_7 regulation of translation K03530 - - 0.000000000000000000000000000000002703 132.0
HKD3_k127_6125804_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1148.0
HKD3_k127_6125804_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 4.071e-277 900.0
HKD3_k127_6125804_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.501e-235 737.0
HKD3_k127_6125804_3 Deoxyhypusine synthase K00809 - 2.5.1.46 1.357e-206 653.0
HKD3_k127_6125804_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HKD3_k127_6125804_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 256.0
HKD3_k127_6125804_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
HKD3_k127_6125804_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000004151 165.0
HKD3_k127_6126978_0 PAP2 superfamily C-terminal - - - 0.0000000000000000000000000000000000000000000004482 174.0
HKD3_k127_6126978_1 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000001709 156.0
HKD3_k127_6126978_3 Psort location CytoplasmicMembrane, score 10.00 K03320 - - 0.0001913 53.0
HKD3_k127_6127947_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1967.0
HKD3_k127_6127947_1 oligopeptide transporter, OPT family - - - 3.384e-320 995.0
HKD3_k127_6127947_10 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 424.0
HKD3_k127_6127947_12 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000009151 225.0
HKD3_k127_6127947_13 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000009561 218.0
HKD3_k127_6127947_14 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000004327 207.0
HKD3_k127_6127947_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000025 171.0
HKD3_k127_6127947_16 Regulatory protein, FmdB family - - - 0.000000000000000000000002993 104.0
HKD3_k127_6127947_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000001208 96.0
HKD3_k127_6127947_19 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000002266 64.0
HKD3_k127_6127947_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 8.503e-289 896.0
HKD3_k127_6127947_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.747e-216 679.0
HKD3_k127_6127947_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 571.0
HKD3_k127_6127947_5 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 497.0
HKD3_k127_6127947_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 493.0
HKD3_k127_6127947_7 metalloendopeptidase activity K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 466.0
HKD3_k127_6127947_8 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 436.0
HKD3_k127_6127947_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 437.0
HKD3_k127_6146185_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.131e-198 649.0
HKD3_k127_6146185_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 598.0
HKD3_k127_6146185_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000009346 68.0
HKD3_k127_6146185_4 Belongs to the N-Me-Phe pilin family K02650 - - 0.00001745 58.0
HKD3_k127_6149380_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1126.0
HKD3_k127_6149380_1 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 2.834e-229 715.0
HKD3_k127_6149380_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008056 258.0
HKD3_k127_6149380_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001384 243.0
HKD3_k127_6154977_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1074.0
HKD3_k127_6154977_1 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 2.103e-310 959.0
HKD3_k127_6154977_10 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 300.0
HKD3_k127_6154977_11 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
HKD3_k127_6154977_12 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000007737 243.0
HKD3_k127_6154977_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000007892 184.0
HKD3_k127_6154977_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000001431 169.0
HKD3_k127_6154977_15 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000004712 182.0
HKD3_k127_6154977_16 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001017 117.0
HKD3_k127_6154977_17 Rieske [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000000001709 117.0
HKD3_k127_6154977_2 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 2.213e-228 728.0
HKD3_k127_6154977_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.36e-213 668.0
HKD3_k127_6154977_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 604.0
HKD3_k127_6154977_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 587.0
HKD3_k127_6154977_6 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 546.0
HKD3_k127_6154977_7 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 430.0
HKD3_k127_6154977_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
HKD3_k127_6154977_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 327.0
HKD3_k127_6172718_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 639.0
HKD3_k127_6172718_1 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 417.0
HKD3_k127_6172718_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 355.0
HKD3_k127_6172718_3 PAS domain - - - 0.0000000000000000000000000000000000001963 159.0
HKD3_k127_6172718_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000002217 94.0
HKD3_k127_6172718_5 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000009792 61.0
HKD3_k127_6174926_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.512e-264 832.0
HKD3_k127_6174926_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.475e-203 642.0
HKD3_k127_6174926_10 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000001271 242.0
HKD3_k127_6174926_11 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000001613 213.0
HKD3_k127_6174926_12 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000003028 211.0
HKD3_k127_6174926_13 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000001183 188.0
HKD3_k127_6174926_14 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000002076 126.0
HKD3_k127_6174926_15 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000005922 129.0
HKD3_k127_6174926_16 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000001416 107.0
HKD3_k127_6174926_17 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000001086 92.0
HKD3_k127_6174926_18 Ferric siderophore transporter, periplasmic energy transduction protein TonB K03832 - - 0.00000000000004578 84.0
HKD3_k127_6174926_19 PFAM FecR protein - - - 0.000000000002446 81.0
HKD3_k127_6174926_2 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 575.0
HKD3_k127_6174926_20 FecR protein - - - 0.000000208 63.0
HKD3_k127_6174926_3 Periplasmic protein TonB links inner and outer membranes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 549.0
HKD3_k127_6174926_4 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 442.0
HKD3_k127_6174926_5 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 438.0
HKD3_k127_6174926_6 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 400.0
HKD3_k127_6174926_7 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 361.0
HKD3_k127_6174926_8 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003468 293.0
HKD3_k127_6174926_9 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001006 250.0
HKD3_k127_6175939_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.775e-287 888.0
HKD3_k127_6175939_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 410.0
HKD3_k127_6175939_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 321.0
HKD3_k127_6175939_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002385 243.0
HKD3_k127_6175939_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000003878 228.0
HKD3_k127_6175939_5 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000001449 193.0
HKD3_k127_6181127_0 DEAD/H associated K03724 - - 0.0 1688.0
HKD3_k127_6181127_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 545.0
HKD3_k127_6181127_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 366.0
HKD3_k127_6181127_3 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 360.0
HKD3_k127_6181127_4 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000005471 205.0
HKD3_k127_6181127_5 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000004177 149.0
HKD3_k127_6181127_6 - - - - 0.000000000000000000000000237 113.0
HKD3_k127_6182552_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 599.0
HKD3_k127_6182552_1 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 506.0
HKD3_k127_6182552_2 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 447.0
HKD3_k127_6182552_3 Cytochrome c K00406,K08906 - - 0.00000000000000000000001392 102.0
HKD3_k127_6184696_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 396.0
HKD3_k127_6184696_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 326.0
HKD3_k127_6184696_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000471 262.0
HKD3_k127_6184696_3 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000000007592 211.0
HKD3_k127_6184696_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000009567 144.0
HKD3_k127_6184696_5 YCII-related domain - - - 0.00000000000000000000003347 105.0
HKD3_k127_6184696_6 oxygen carrier activity K07216 - - 0.000000000000000000006643 98.0
HKD3_k127_6190385_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 2.826e-209 668.0
HKD3_k127_6190385_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 522.0
HKD3_k127_6190385_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 409.0
HKD3_k127_6190385_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 353.0
HKD3_k127_6190385_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 356.0
HKD3_k127_6215465_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.267e-206 646.0
HKD3_k127_6215465_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 604.0
HKD3_k127_6215465_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 460.0
HKD3_k127_6215465_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000001853 233.0
HKD3_k127_6215465_4 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000004861 242.0
HKD3_k127_6215465_5 Protein of unknown function (FYDLN_acid) - - - 0.00000000000000000000004769 100.0
HKD3_k127_6215465_7 Protein of unknown function (DUF3006) - - - 0.000009081 50.0
HKD3_k127_6238379_0 PFAM Polysulphide reductase, NrfD - - - 8.277e-200 646.0
HKD3_k127_6238379_1 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 548.0
HKD3_k127_6238379_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 492.0
HKD3_k127_6238379_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 404.0
HKD3_k127_6238379_4 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
HKD3_k127_6238379_5 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
HKD3_k127_6238379_6 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002452 247.0
HKD3_k127_6238379_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
HKD3_k127_6238379_8 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000499 222.0
HKD3_k127_6238379_9 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000007119 207.0
HKD3_k127_6262825_0 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 552.0
HKD3_k127_6262825_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 520.0
HKD3_k127_6262825_2 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 471.0
HKD3_k127_6262825_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000147 73.0
HKD3_k127_6275364_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 1.406e-309 964.0
HKD3_k127_6275364_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 557.0
HKD3_k127_6275364_2 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
HKD3_k127_6275364_3 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 297.0
HKD3_k127_6275364_4 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002753 271.0
HKD3_k127_6275364_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000001349 254.0
HKD3_k127_6275364_6 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0000000000000000000000007049 106.0
HKD3_k127_6296943_0 Heat shock 70 kDa protein K04043 - - 1.861e-270 840.0
HKD3_k127_6296943_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 431.0
HKD3_k127_6296943_2 Sterol carrier protein - - - 0.0000000000000000000000000000000000007575 160.0
HKD3_k127_6405444_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1034.0
HKD3_k127_6405444_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.353e-316 1003.0
HKD3_k127_6405444_10 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 471.0
HKD3_k127_6405444_11 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 417.0
HKD3_k127_6405444_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 385.0
HKD3_k127_6405444_13 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 359.0
HKD3_k127_6405444_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 366.0
HKD3_k127_6405444_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 354.0
HKD3_k127_6405444_16 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 314.0
HKD3_k127_6405444_17 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003511 283.0
HKD3_k127_6405444_18 regulator K07773 - - 0.00000000000000000000000000000000000000000000000000000000000000000006607 237.0
HKD3_k127_6405444_19 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000003997 212.0
HKD3_k127_6405444_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 9.062e-280 866.0
HKD3_k127_6405444_20 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
HKD3_k127_6405444_21 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000001116 123.0
HKD3_k127_6405444_22 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000000000001706 97.0
HKD3_k127_6405444_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.122e-255 793.0
HKD3_k127_6405444_4 ABC-type transport system involved in lipoprotein release permease component K09808 - - 4.294e-222 745.0
HKD3_k127_6405444_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 626.0
HKD3_k127_6405444_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 587.0
HKD3_k127_6405444_7 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 573.0
HKD3_k127_6405444_8 DnaJ molecular chaperone homology domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 542.0
HKD3_k127_6405444_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 477.0
HKD3_k127_6492313_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 589.0
HKD3_k127_6492313_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 531.0
HKD3_k127_6492313_10 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000143 166.0
HKD3_k127_6492313_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000001238 130.0
HKD3_k127_6492313_12 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000003695 76.0
HKD3_k127_6492313_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 455.0
HKD3_k127_6492313_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 365.0
HKD3_k127_6492313_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 353.0
HKD3_k127_6492313_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 341.0
HKD3_k127_6492313_6 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 322.0
HKD3_k127_6492313_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009047 293.0
HKD3_k127_6492313_8 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.0000000000000000000000000000000000000000000000000009658 207.0
HKD3_k127_6492313_9 - - - - 0.00000000000000000000000000000000000000000000000001422 198.0
HKD3_k127_65237_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.705e-315 1020.0
HKD3_k127_65237_1 7TM receptor with intracellular HD hydrolase K07037 - - 5.608e-217 698.0
HKD3_k127_65237_10 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 405.0
HKD3_k127_65237_11 PilZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 394.0
HKD3_k127_65237_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 320.0
HKD3_k127_65237_13 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
HKD3_k127_65237_14 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001469 244.0
HKD3_k127_65237_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000002809 192.0
HKD3_k127_65237_16 protein trimerization - - - 0.000000000000000000000000000000000000000000669 167.0
HKD3_k127_65237_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 5.806e-204 658.0
HKD3_k127_65237_3 twitching motility protein K02669 - - 3.467e-198 621.0
HKD3_k127_65237_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 624.0
HKD3_k127_65237_5 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 560.0
HKD3_k127_65237_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 497.0
HKD3_k127_65237_7 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
HKD3_k127_65237_8 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 451.0
HKD3_k127_65237_9 nuclear chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 471.0
HKD3_k127_6546423_0 Putative modulator of DNA gyrase K03568 - - 1.395e-246 770.0
HKD3_k127_6546423_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 596.0
HKD3_k127_6546423_2 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
HKD3_k127_6546423_4 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000004529 208.0
HKD3_k127_6546423_5 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000005045 203.0
HKD3_k127_6546423_7 Cytochrome c K00406,K08906 - - 0.00000003487 59.0
HKD3_k127_6566873_0 Belongs to the amidase family K01426 - 3.5.1.4 6.712e-200 644.0
HKD3_k127_6566873_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 471.0
HKD3_k127_6566873_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 458.0
HKD3_k127_6566873_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001523 233.0
HKD3_k127_6566873_4 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001968 224.0
HKD3_k127_6566873_5 - - - - 0.000000000000000000000000000000001645 132.0
HKD3_k127_6566873_6 - - - - 0.000000000000000000000000000000002947 138.0
HKD3_k127_6566873_7 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000005759 123.0
HKD3_k127_6566873_8 - - - - 0.000000000000000000000009783 113.0
HKD3_k127_6566873_9 - - - - 0.0000000003836 72.0
HKD3_k127_6661022_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 7.594e-205 644.0
HKD3_k127_6661022_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 499.0
HKD3_k127_6661022_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 453.0
HKD3_k127_6661022_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 417.0
HKD3_k127_6661022_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
HKD3_k127_6661022_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000004135 201.0
HKD3_k127_6661022_6 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000001221 183.0
HKD3_k127_6661022_7 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000006199 168.0
HKD3_k127_6661022_8 Domain of unknown function (DUF4833) - - - 0.0000000000000000000001034 106.0
HKD3_k127_6760466_0 glutamate--cysteine ligase K01919 - 6.3.2.2 6.289e-216 682.0
HKD3_k127_6760466_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.445e-203 644.0
HKD3_k127_6760466_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 479.0
HKD3_k127_6774850_0 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 363.0
HKD3_k127_6774850_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
HKD3_k127_6774850_2 negative regulation of translational initiation - - - 0.00000000000000000001897 100.0
HKD3_k127_6774850_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000004525 83.0
HKD3_k127_67782_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1129.0
HKD3_k127_67782_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 477.0
HKD3_k127_67782_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 400.0
HKD3_k127_67782_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
HKD3_k127_67782_4 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 370.0
HKD3_k127_67782_5 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000001629 173.0
HKD3_k127_67782_7 - - - - 0.00000000000000002748 88.0
HKD3_k127_6794207_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1173.0
HKD3_k127_6794207_1 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 349.0
HKD3_k127_6794207_2 4Fe-4S binding domain protein K02574 - - 0.0000000000000000000000000000000000000000001647 168.0
HKD3_k127_6794207_3 - - - - 0.0000000000000000000000000000000000005986 160.0
HKD3_k127_6794207_4 heat shock protein binding - - - 0.000000000000000000000000000002068 126.0
HKD3_k127_6794207_5 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000214 128.0
HKD3_k127_6794207_7 4Fe-4S binding domain K02574 - - 0.0000000000000000007891 100.0
HKD3_k127_6794207_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000001438 68.0
HKD3_k127_6852473_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.09e-208 661.0
HKD3_k127_6852473_1 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 615.0
HKD3_k127_6852473_11 - - - - 0.0000000000000000000000000000000000001129 148.0
HKD3_k127_6852473_12 - - - - 0.0000004301 54.0
HKD3_k127_6852473_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 531.0
HKD3_k127_6852473_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 430.0
HKD3_k127_6852473_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 332.0
HKD3_k127_6852473_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 304.0
HKD3_k127_6852473_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000002548 245.0
HKD3_k127_6852473_8 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000002704 224.0
HKD3_k127_6852473_9 Protein conserved in bacteria K09986 - - 0.00000000000000000000000000000000000000000000001934 180.0
HKD3_k127_692186_0 soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 587.0
HKD3_k127_692186_1 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 513.0
HKD3_k127_692186_2 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 367.0
HKD3_k127_692186_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 361.0
HKD3_k127_692186_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000375 294.0
HKD3_k127_692186_6 Flagellar assembly protein FliH K02411,K03223 - - 0.00000000000000000000000000000002316 136.0
HKD3_k127_692186_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000003843 63.0
HKD3_k127_7086184_0 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 440.0
HKD3_k127_7086184_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 402.0
HKD3_k127_7086184_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 280.0
HKD3_k127_7086184_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000001195 238.0
HKD3_k127_71217_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0 1008.0
HKD3_k127_71217_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.45e-272 844.0
HKD3_k127_71217_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 7.688e-205 662.0
HKD3_k127_71217_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 350.0
HKD3_k127_71217_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001646 307.0
HKD3_k127_71217_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002055 296.0
HKD3_k127_71217_6 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000006794 174.0
HKD3_k127_713920_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 1.767e-217 680.0
HKD3_k127_713920_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 569.0
HKD3_k127_713920_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 327.0
HKD3_k127_713920_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001307 289.0
HKD3_k127_713920_4 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002804 276.0
HKD3_k127_713920_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000002038 148.0
HKD3_k127_72096_0 Bacterial transcriptional activator domain - - - 0.0 1043.0
HKD3_k127_72096_1 Peptidase, M61 - - - 2.25e-234 733.0
HKD3_k127_7261203_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 599.0
HKD3_k127_7261203_1 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 580.0
HKD3_k127_7261203_10 Response regulator, receiver - - - 0.0000000000000000000000000000000000003256 147.0
HKD3_k127_7261203_12 FecR protein - - - 0.00000009269 62.0
HKD3_k127_7261203_14 FecR protein - - - 0.0002461 53.0
HKD3_k127_7261203_15 - - - - 0.0003338 53.0
HKD3_k127_7261203_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 439.0
HKD3_k127_7261203_4 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 388.0
HKD3_k127_7261203_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 303.0
HKD3_k127_7261203_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
HKD3_k127_7261203_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000001084 261.0
HKD3_k127_7261203_8 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000009716 243.0
HKD3_k127_7261203_9 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000006023 216.0
HKD3_k127_7266083_0 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 8.334e-286 895.0
HKD3_k127_7266083_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.767e-222 735.0
HKD3_k127_7266083_10 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000005114 164.0
HKD3_k127_7266083_11 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000008432 100.0
HKD3_k127_7266083_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 2.208e-205 651.0
HKD3_k127_7266083_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.645e-198 632.0
HKD3_k127_7266083_4 mitochondrial electron transport, ubiquinol to cytochrome c K01412,K07263,K17732 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005759,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016787,GO:0017087,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0023052,GO:0031090,GO:0031930,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045275,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0065007,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 3.4.24.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 447.0
HKD3_k127_7266083_5 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 366.0
HKD3_k127_7266083_6 glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 313.0
HKD3_k127_7266083_7 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000031 188.0
HKD3_k127_7266083_8 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000138 168.0
HKD3_k127_7266083_9 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000000000002974 159.0
HKD3_k127_7269603_0 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 335.0
HKD3_k127_7269603_1 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000005685 175.0
HKD3_k127_7269603_2 Bacteriophage replication gene A protein (GPA) - - - 0.000000002 69.0
HKD3_k127_7269603_3 Phage terminase, small subunit - - - 0.0003959 49.0
HKD3_k127_7272193_0 Methionine synthase K00548 - 2.1.1.13 0.0 1824.0
HKD3_k127_7272193_1 UPF0313 protein - - - 1.167e-315 976.0
HKD3_k127_7272193_10 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000005519 178.0
HKD3_k127_7272193_11 domain, Protein - - - 0.0000000000000000000000000000000000000001344 165.0
HKD3_k127_7272193_12 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000001324 128.0
HKD3_k127_7272193_13 Late embryogenesis abundant protein - - - 0.000000000000000000000000132 113.0
HKD3_k127_7272193_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.477e-198 626.0
HKD3_k127_7272193_3 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 595.0
HKD3_k127_7272193_4 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 541.0
HKD3_k127_7272193_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 319.0
HKD3_k127_7272193_6 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 296.0
HKD3_k127_7272193_7 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001211 280.0
HKD3_k127_7272193_8 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
HKD3_k127_7272193_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000002534 251.0
HKD3_k127_7298717_0 Heat shock 70 kDa protein K04043 - - 4.754e-283 876.0
HKD3_k127_7298717_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 557.0
HKD3_k127_7298717_2 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 406.0
HKD3_k127_7298717_3 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 329.0
HKD3_k127_7298717_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009574 283.0
HKD3_k127_7298717_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000007455 248.0
HKD3_k127_7298717_6 toxin biosynthetic process K03558 - - 0.0000000000000006303 87.0
HKD3_k127_7300319_0 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 530.0
HKD3_k127_7300319_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000002935 94.0
HKD3_k127_7305012_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.02e-284 900.0
HKD3_k127_7305012_1 radical SAM domain protein - - - 4.042e-196 619.0
HKD3_k127_7305012_10 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001965 265.0
HKD3_k127_7305012_11 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000001108 234.0
HKD3_k127_7305012_12 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.000000000000000000000000000000000000000000000003328 178.0
HKD3_k127_7305012_13 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000001429 166.0
HKD3_k127_7305012_14 Serine aminopeptidase, S33 K07018 - - 0.00000000000000000000002462 116.0
HKD3_k127_7305012_15 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.00000000000000000000007857 108.0
HKD3_k127_7305012_16 AntiSigma factor - - - 0.00000000000000007595 91.0
HKD3_k127_7305012_17 Purple acid Phosphatase, N-terminal domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001565 78.0
HKD3_k127_7305012_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 587.0
HKD3_k127_7305012_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 617.0
HKD3_k127_7305012_4 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 454.0
HKD3_k127_7305012_5 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 460.0
HKD3_k127_7305012_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 305.0
HKD3_k127_7305012_7 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002258 279.0
HKD3_k127_7305012_8 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004808 284.0
HKD3_k127_7305012_9 PFAM Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002305 289.0
HKD3_k127_7310309_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1278.0
HKD3_k127_7310309_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 439.0
HKD3_k127_7310309_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 409.0
HKD3_k127_7310309_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 346.0
HKD3_k127_7310309_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 315.0
HKD3_k127_7310309_5 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000001824 247.0
HKD3_k127_7310309_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000004202 191.0
HKD3_k127_7310309_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000004637 154.0
HKD3_k127_7310309_8 - - - - 0.0000000000000000000006194 97.0
HKD3_k127_7323492_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1131.0
HKD3_k127_7323492_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.871e-275 857.0
HKD3_k127_7323492_10 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 306.0
HKD3_k127_7323492_11 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002001 296.0
HKD3_k127_7323492_13 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002001 258.0
HKD3_k127_7323492_14 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000001429 239.0
HKD3_k127_7323492_15 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000001447 180.0
HKD3_k127_7323492_17 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000000002698 157.0
HKD3_k127_7323492_18 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000001285 172.0
HKD3_k127_7323492_19 MacB-like periplasmic core domain - - - 0.000000000000000000000000000001392 141.0
HKD3_k127_7323492_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 1.968e-262 827.0
HKD3_k127_7323492_20 Thiamine-binding protein - - - 0.00000000000000000009183 102.0
HKD3_k127_7323492_21 - - - - 0.000000000000002969 90.0
HKD3_k127_7323492_3 heat shock protein binding - - - 2.072e-211 707.0
HKD3_k127_7323492_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 591.0
HKD3_k127_7323492_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 611.0
HKD3_k127_7323492_6 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 556.0
HKD3_k127_7323492_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 477.0
HKD3_k127_7323492_8 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 327.0
HKD3_k127_7323492_9 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 309.0
HKD3_k127_7331630_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1182.0
HKD3_k127_7331630_1 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 443.0
HKD3_k127_7331630_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
HKD3_k127_7331630_3 Penicillin acylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 372.0
HKD3_k127_7331630_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HKD3_k127_7331630_5 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005063 254.0
HKD3_k127_7331630_6 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000003111 241.0
HKD3_k127_7331630_7 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000006524 206.0
HKD3_k127_7331630_8 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000000000000000000000000000000000000000007277 173.0
HKD3_k127_7331630_9 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000000000001807 139.0
HKD3_k127_7332300_0 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 4.948e-263 820.0
HKD3_k127_7332300_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.776e-226 706.0
HKD3_k127_7332300_10 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003518 250.0
HKD3_k127_7332300_11 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003881 252.0
HKD3_k127_7332300_12 PFAM Pyruvate K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000001574 201.0
HKD3_k127_7332300_13 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000007349 202.0
HKD3_k127_7332300_14 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.000000000000000000000000000000000000000000564 165.0
HKD3_k127_7332300_15 COG1073 hydrolases of the alpha beta superfamily - - - 0.000000000000000005169 94.0
HKD3_k127_7332300_16 Transposase IS200 like K07491 - - 0.00000000001444 67.0
HKD3_k127_7332300_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00008546 51.0
HKD3_k127_7332300_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 621.0
HKD3_k127_7332300_3 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 599.0
HKD3_k127_7332300_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 524.0
HKD3_k127_7332300_5 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 455.0
HKD3_k127_7332300_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 414.0
HKD3_k127_7332300_7 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 420.0
HKD3_k127_7332300_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 373.0
HKD3_k127_7332300_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 324.0
HKD3_k127_7336531_0 PrkA AAA domain K07180 - - 0.0 1311.0
HKD3_k127_7336531_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 447.0
HKD3_k127_7336531_10 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000002199 123.0
HKD3_k127_7336531_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 424.0
HKD3_k127_7336531_3 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 374.0
HKD3_k127_7336531_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000007699 191.0
HKD3_k127_7336531_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000006185 147.0
HKD3_k127_7336531_6 Cold shock protein K03704 - - 0.00000000000000000000000000000000006556 135.0
HKD3_k127_7336531_7 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000001136 135.0
HKD3_k127_7336531_8 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000137 127.0
HKD3_k127_7343950_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 2.218e-248 784.0
HKD3_k127_7343950_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 539.0
HKD3_k127_7343950_2 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 439.0
HKD3_k127_7343950_3 Sodium:solute symporter family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 405.0
HKD3_k127_7344149_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 2035.0
HKD3_k127_7344149_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 544.0
HKD3_k127_7344149_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000004686 242.0
HKD3_k127_7344149_3 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000003203 222.0
HKD3_k127_7344149_4 NUDIX domain - - - 0.0000000000000000000000000000000000000008682 155.0
HKD3_k127_7344149_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.0000000000000000000000000000000000001219 166.0
HKD3_k127_7344149_6 oxidoreductase, short-chain dehydrogenase reductase family K07124 - - 0.0000000000000000000000000000000003638 137.0
HKD3_k127_7345712_0 Peptidase family M13 K01415,K07386 - 3.4.24.71 2.633e-254 804.0
HKD3_k127_7345712_1 signal peptide peptidase SppA, 36K type K04773 - - 5.818e-219 707.0
HKD3_k127_7345712_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 551.0
HKD3_k127_7345712_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 499.0
HKD3_k127_7345712_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000009973 224.0
HKD3_k127_7345712_5 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000379 188.0
HKD3_k127_7364474_0 acetyl-CoA hydrolase K18118 - 2.8.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 602.0
HKD3_k127_7364474_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 485.0
HKD3_k127_7364474_2 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 375.0
HKD3_k127_7368023_0 Formate dehydrogenase, alpha subunit K00123 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009326,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016622,GO:0016903,GO:0018282,GO:0018289,GO:0018291,GO:0019538,GO:0022607,GO:0031163,GO:0032991,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0047111,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:1901564,GO:1902494 1.17.1.9 0.0 1253.0
HKD3_k127_7368023_1 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0 1058.0
HKD3_k127_7368023_10 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000000000007338 225.0
HKD3_k127_7368023_11 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000003483 219.0
HKD3_k127_7368023_12 DTW - - - 0.0000000000000000000000000000000000000000000000001898 194.0
HKD3_k127_7368023_2 Alpha/beta hydrolase family K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 458.0
HKD3_k127_7368023_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 451.0
HKD3_k127_7368023_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 439.0
HKD3_k127_7368023_5 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 398.0
HKD3_k127_7368023_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
HKD3_k127_7368023_7 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
HKD3_k127_7368023_8 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000187 277.0
HKD3_k127_7368023_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000003386 248.0
HKD3_k127_7369807_0 AcrB/AcrD/AcrF family - - - 1.191e-320 1012.0
HKD3_k127_7369807_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 415.0
HKD3_k127_7369807_2 ABC transporter, ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 373.0
HKD3_k127_7369807_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000163 158.0
HKD3_k127_7373489_0 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 393.0
HKD3_k127_7373489_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 351.0
HKD3_k127_7373489_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007387 246.0
HKD3_k127_7373489_3 - - - - 0.00000000000000000000000000000000001219 140.0
HKD3_k127_7373489_4 - - - - 0.00000000000002006 78.0
HKD3_k127_7373489_5 - - - - 0.000008213 55.0
HKD3_k127_7382333_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1041.0
HKD3_k127_7382333_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.965e-197 676.0
HKD3_k127_7382333_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 287.0
HKD3_k127_7382333_11 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 302.0
HKD3_k127_7382333_12 protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000000000000000000002177 222.0
HKD3_k127_7382333_13 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000001816 199.0
HKD3_k127_7382333_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000003938 159.0
HKD3_k127_7382333_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 556.0
HKD3_k127_7382333_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 539.0
HKD3_k127_7382333_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 485.0
HKD3_k127_7382333_5 imidazolonepropionase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 443.0
HKD3_k127_7382333_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 420.0
HKD3_k127_7382333_7 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 425.0
HKD3_k127_7382333_8 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 331.0
HKD3_k127_7382333_9 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
HKD3_k127_7391904_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1399.0
HKD3_k127_7391904_1 Aminotransferase K01845 - 5.4.3.8 3.12e-219 703.0
HKD3_k127_7391904_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 529.0
HKD3_k127_7391904_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 396.0
HKD3_k127_7391904_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 336.0
HKD3_k127_7395772_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1107.0
HKD3_k127_7395772_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.045e-277 858.0
HKD3_k127_7395772_10 cysteine-type peptidase activity K13695 - - 0.00000000000000000000000000000000000195 148.0
HKD3_k127_7395772_11 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000000005962 134.0
HKD3_k127_7395772_12 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000004652 125.0
HKD3_k127_7395772_14 Pfam:DUF2029 - - - 0.000000000000000000000000005171 125.0
HKD3_k127_7395772_16 SMART Rhodanese domain protein - - - 0.000001045 50.0
HKD3_k127_7395772_2 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 1.105e-240 754.0
HKD3_k127_7395772_3 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 4.819e-220 691.0
HKD3_k127_7395772_4 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 582.0
HKD3_k127_7395772_5 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 576.0
HKD3_k127_7395772_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 499.0
HKD3_k127_7395772_7 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 497.0
HKD3_k127_7395772_8 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 483.0
HKD3_k127_7395772_9 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 493.0
HKD3_k127_7398226_0 PFAM Alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 544.0
HKD3_k127_7398226_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 524.0
HKD3_k127_7398226_2 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 438.0
HKD3_k127_7398226_3 Oxidoreductase, FAD FMN-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 395.0
HKD3_k127_7398226_4 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 341.0
HKD3_k127_7398226_5 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 312.0
HKD3_k127_7398226_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000001016 289.0
HKD3_k127_7398226_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
HKD3_k127_7398226_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000005864 133.0
HKD3_k127_7398226_9 carboxylase K01968 - 6.4.1.4 0.00000007777 66.0
HKD3_k127_7405326_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 5.481e-268 854.0
HKD3_k127_7405326_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 537.0
HKD3_k127_7405326_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 301.0
HKD3_k127_7405326_11 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 309.0
HKD3_k127_7405326_12 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000009484 206.0
HKD3_k127_7405326_13 PFAM Amino acid-binding ACT - - - 0.00000000000000000000000000000000000001773 159.0
HKD3_k127_7405326_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 488.0
HKD3_k127_7405326_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 416.0
HKD3_k127_7405326_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 407.0
HKD3_k127_7405326_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 387.0
HKD3_k127_7405326_6 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 319.0
HKD3_k127_7405326_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 321.0
HKD3_k127_7405326_8 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 328.0
HKD3_k127_7405326_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 302.0
HKD3_k127_7441069_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.453e-319 995.0
HKD3_k127_7441069_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.085e-259 810.0
HKD3_k127_7441069_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 317.0
HKD3_k127_7441069_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 296.0
HKD3_k127_7441069_12 GGDEF domain K21009 - - 0.00000000000000000000000000000000000000000000000000000000000000002797 248.0
HKD3_k127_7441069_13 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000002705 200.0
HKD3_k127_7441069_14 response regulator K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000003499 177.0
HKD3_k127_7441069_15 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000265 145.0
HKD3_k127_7441069_16 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000004158 124.0
HKD3_k127_7441069_18 Peroxiredoxin K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000002177 70.0
HKD3_k127_7441069_19 phosphohistidine phosphatase, SixA K08296 - - 0.00000009584 54.0
HKD3_k127_7441069_2 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 2.848e-236 741.0
HKD3_k127_7441069_21 Protein of unknown function (DUF2997) - - - 0.00008558 47.0
HKD3_k127_7441069_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 561.0
HKD3_k127_7441069_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 520.0
HKD3_k127_7441069_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 497.0
HKD3_k127_7441069_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 434.0
HKD3_k127_7441069_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 384.0
HKD3_k127_7441069_8 - K06198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 365.0
HKD3_k127_7441069_9 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 351.0
HKD3_k127_7454036_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1441.0
HKD3_k127_7454036_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1120.0
HKD3_k127_7454036_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 427.0
HKD3_k127_7454036_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
HKD3_k127_7454036_12 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
HKD3_k127_7454036_13 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 312.0
HKD3_k127_7454036_14 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 310.0
HKD3_k127_7454036_15 chemotaxis K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
HKD3_k127_7454036_16 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000000005623 216.0
HKD3_k127_7454036_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000005048 195.0
HKD3_k127_7454036_18 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000248 166.0
HKD3_k127_7454036_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.942e-285 884.0
HKD3_k127_7454036_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.002e-238 748.0
HKD3_k127_7454036_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.366e-218 688.0
HKD3_k127_7454036_5 Protein of unknown function (DUF1343) - - - 7.412e-194 616.0
HKD3_k127_7454036_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 556.0
HKD3_k127_7454036_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 534.0
HKD3_k127_7454036_8 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 495.0
HKD3_k127_7454036_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 422.0
HKD3_k127_7456593_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1238.0
HKD3_k127_7456593_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.836e-244 757.0
HKD3_k127_7456593_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 597.0
HKD3_k127_7456593_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 374.0
HKD3_k127_7456593_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000009735 211.0
HKD3_k127_7456593_6 - - - - 0.000000000004089 73.0
HKD3_k127_7494781_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2217.0
HKD3_k127_7494781_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000007286 156.0
HKD3_k127_7513335_0 DNA polymerase beta thumb K02347 - - 3.662e-244 768.0
HKD3_k127_7513335_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.691e-217 681.0
HKD3_k127_7513335_10 Forkhead associated domain - - - 0.00000000000000000000000000006571 117.0
HKD3_k127_7513335_11 nitrite reductase [NAD(P)H] activity K05710 - - 0.00000000000000000000000002926 116.0
HKD3_k127_7513335_13 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000532 101.0
HKD3_k127_7513335_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 562.0
HKD3_k127_7513335_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 555.0
HKD3_k127_7513335_4 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 467.0
HKD3_k127_7513335_5 Diadenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 420.0
HKD3_k127_7513335_6 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 393.0
HKD3_k127_7513335_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 374.0
HKD3_k127_7513335_8 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000007775 261.0
HKD3_k127_7513335_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000008454 220.0
HKD3_k127_7517705_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 473.0
HKD3_k127_7517705_1 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 412.0
HKD3_k127_7517705_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005772 261.0
HKD3_k127_7517705_3 - - - - 0.000000000000000000000000000000000000000000000001489 198.0
HKD3_k127_7517705_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000007997 139.0
HKD3_k127_7517705_5 Amidohydrolase - - - 0.00000000000000000000000000000008066 137.0
HKD3_k127_75377_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 2.486e-237 745.0
HKD3_k127_75377_1 Stage II sporulation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 581.0
HKD3_k127_75377_2 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 413.0
HKD3_k127_75377_3 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
HKD3_k127_75377_5 Rhodanese Homology Domain - - - 0.0000000000000000006908 102.0
HKD3_k127_7538271_0 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 540.0
HKD3_k127_7538271_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 471.0
HKD3_k127_7538271_2 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000000004398 111.0
HKD3_k127_7581004_0 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 345.0
HKD3_k127_7581004_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000002773 166.0
HKD3_k127_7581004_2 TPM domain - - - 0.00000000000000000000000000000000000009528 150.0
HKD3_k127_7581004_3 Glycine cleavage H-protein - - - 0.00000000001576 66.0
HKD3_k127_7581004_4 Glycine cleavage H-protein - - - 0.00000001109 63.0
HKD3_k127_7617380_0 GMC oxidoreductase K00108 - 1.1.99.1 1.025e-240 756.0
HKD3_k127_7617380_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 521.0
HKD3_k127_7617380_10 Thioesterase K07107 - - 0.00000000000000000000000000000000000006103 163.0
HKD3_k127_7617380_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000005927 118.0
HKD3_k127_7617380_2 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 515.0
HKD3_k127_7617380_3 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 465.0
HKD3_k127_7617380_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 437.0
HKD3_k127_7617380_5 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 378.0
HKD3_k127_7617380_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007666 259.0
HKD3_k127_7617380_7 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
HKD3_k127_7617380_8 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000916 236.0
HKD3_k127_7617380_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000002282 245.0
HKD3_k127_7617508_0 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 421.0
HKD3_k127_7617508_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 359.0
HKD3_k127_7617508_10 Universal stress protein - - - 0.0000000000001877 85.0
HKD3_k127_7617508_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 331.0
HKD3_k127_7617508_3 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HKD3_k127_7617508_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 324.0
HKD3_k127_7617508_5 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
HKD3_k127_7617508_6 Calcineurin-like phosphoesterase superfamily domain K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
HKD3_k127_7617508_7 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000001344 221.0
HKD3_k127_7617508_8 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000001518 204.0
HKD3_k127_7617508_9 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000003197 203.0
HKD3_k127_7630479_0 Berberine and berberine like - - - 8.241e-233 728.0
HKD3_k127_7630479_1 Sigma-54 interaction domain K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 597.0
HKD3_k127_7630479_2 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 580.0
HKD3_k127_7630479_3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 380.0
HKD3_k127_7630479_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000834 259.0
HKD3_k127_7630479_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000006392 167.0
HKD3_k127_7636296_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.37e-304 938.0
HKD3_k127_7636296_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 296.0
HKD3_k127_7636296_3 Protein of unknown function (DUF541) K09797 - - 0.0000000000000000000000000000000000000000000000000000000000006522 218.0
HKD3_k127_7636296_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004323 205.0
HKD3_k127_7636296_5 DNA integration K07497 - - 0.0000000000000000000000000000000000000000000000002151 194.0
HKD3_k127_7636296_6 DNA polymerase family A K02334 - 2.7.7.7 0.00000000000000000000000000000002337 145.0
HKD3_k127_7636296_8 PFAM transposase IS3 IS911 family protein K07483 - - 0.00000000000000005141 86.0
HKD3_k127_7636296_9 HTH-like domain K07497 - - 0.000000000003094 68.0
HKD3_k127_7671035_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 484.0
HKD3_k127_7671035_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005978 236.0
HKD3_k127_7695606_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1179.0
HKD3_k127_7695606_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 626.0
HKD3_k127_7695606_2 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 559.0
HKD3_k127_7695606_3 Single Cache domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000519 213.0
HKD3_k127_7695606_4 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000001612 125.0
HKD3_k127_7757026_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1949.0
HKD3_k127_7757026_1 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 1.541e-262 820.0
HKD3_k127_7757026_2 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 581.0
HKD3_k127_7757026_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000005956 238.0
HKD3_k127_7757026_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000001009 154.0
HKD3_k127_7757026_5 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000000000000000000001164 132.0
HKD3_k127_7816690_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
HKD3_k127_7816690_1 - - - - 0.00000000000000000000000000000000000000000000000000000000006557 217.0
HKD3_k127_7816690_2 - - - - 0.00000000000000000000000000000000000003203 149.0
HKD3_k127_7816690_3 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000004714 138.0
HKD3_k127_7816690_4 Helix-turn-helix domain - - - 0.00000000000000001323 90.0
HKD3_k127_7816690_5 - - - - 0.0000000000000001093 88.0
HKD3_k127_7851617_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 331.0
HKD3_k127_7851617_1 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 312.0
HKD3_k127_8068125_0 General secretory system II, protein E domain protein K02454 - - 0.0 1019.0
HKD3_k127_8068125_1 SMART Elongator protein 3 MiaB NifB - - - 1.23e-223 704.0
HKD3_k127_8068125_2 ATPase family associated with various cellular activities (AAA) - - - 1.061e-209 696.0
HKD3_k127_8068125_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 321.0
HKD3_k127_8068125_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000005707 211.0
HKD3_k127_8068125_5 Regulatory protein, FmdB family - - - 0.000000000000001044 91.0
HKD3_k127_8108532_0 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 537.0
HKD3_k127_8108532_1 Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 532.0
HKD3_k127_8108532_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 432.0
HKD3_k127_8108532_3 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 426.0
HKD3_k127_8108532_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000002174 190.0
HKD3_k127_8233959_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1881.0
HKD3_k127_8233959_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 293.0
HKD3_k127_8233959_2 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000003179 192.0
HKD3_k127_8233959_3 PFAM Carbohydrate-selective porin OprB - - - 0.000000000000000002533 86.0
HKD3_k127_8250104_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 6.461e-220 696.0
HKD3_k127_8250104_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000001647 134.0
HKD3_k127_8250104_2 - - - - 0.0000000000000000008822 91.0
HKD3_k127_8273062_0 Elongation factor G, domain IV K02355 - - 0.0 1058.0
HKD3_k127_8273062_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.497e-309 954.0
HKD3_k127_8273062_10 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 369.0
HKD3_k127_8273062_11 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 362.0
HKD3_k127_8273062_12 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 288.0
HKD3_k127_8273062_13 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001257 248.0
HKD3_k127_8273062_14 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 256.0
HKD3_k127_8273062_15 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
HKD3_k127_8273062_16 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000008066 183.0
HKD3_k127_8273062_17 - - - - 0.00000000000000000000000007166 107.0
HKD3_k127_8273062_18 GyrI-like small molecule binding domain - - - 0.0000000000000000000000006616 122.0
HKD3_k127_8273062_19 Belongs to the UPF0434 family K09791 - - 0.00000000000000000009917 90.0
HKD3_k127_8273062_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.332e-273 853.0
HKD3_k127_8273062_20 - - - - 0.000000000000004164 80.0
HKD3_k127_8273062_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 3.921e-201 652.0
HKD3_k127_8273062_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 519.0
HKD3_k127_8273062_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 439.0
HKD3_k127_8273062_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 430.0
HKD3_k127_8273062_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 409.0
HKD3_k127_8273062_8 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 406.0
HKD3_k127_8273062_9 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 379.0
HKD3_k127_8461405_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1245.0
HKD3_k127_8461405_1 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 3.712e-239 747.0
HKD3_k127_8461405_10 FemAB family K05363,K11693 - 2.3.2.10,2.3.2.16 0.0000000008273 71.0
HKD3_k127_8461405_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 548.0
HKD3_k127_8461405_3 Psort location CytoplasmicMembrane, score 10.00 K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 552.0
HKD3_k127_8461405_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 473.0
HKD3_k127_8461405_5 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 349.0
HKD3_k127_8461405_6 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 332.0
HKD3_k127_8461405_7 LysM domain - - - 0.0000000000000000000000000000000000000000004056 167.0
HKD3_k127_8461405_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000008877 143.0
HKD3_k127_8461405_9 Belongs to the P(II) protein family K04751 - - 0.00000000000005344 71.0
HKD3_k127_8468455_0 response regulator - - - 1.513e-224 741.0
HKD3_k127_8468455_1 Efflux ABC transporter, permease ATP-binding protein K06147 - - 1.282e-221 721.0
HKD3_k127_8468455_2 HAMP domain K02482 - 2.7.13.3 4.375e-194 622.0
HKD3_k127_8468455_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 472.0
HKD3_k127_8468455_4 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 362.0
HKD3_k127_8468455_5 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000000000000000000005283 224.0
HKD3_k127_8468455_6 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001682 155.0
HKD3_k127_8468458_0 Cytochrome C assembly protein - - - 3.143e-318 990.0
HKD3_k127_8468458_1 Cytochrome C assembly protein - - - 1.247e-286 890.0
HKD3_k127_8468458_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 401.0
HKD3_k127_8468458_11 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 342.0
HKD3_k127_8468458_12 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 323.0
HKD3_k127_8468458_13 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 324.0
HKD3_k127_8468458_14 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002145 272.0
HKD3_k127_8468458_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K12677 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004914 273.0
HKD3_k127_8468458_16 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000005592 250.0
HKD3_k127_8468458_17 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000008877 242.0
HKD3_k127_8468458_18 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000004183 228.0
HKD3_k127_8468458_19 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000003825 245.0
HKD3_k127_8468458_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 4.821e-199 632.0
HKD3_k127_8468458_20 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000003534 223.0
HKD3_k127_8468458_21 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000003306 201.0
HKD3_k127_8468458_22 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000003716 192.0
HKD3_k127_8468458_23 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000002892 186.0
HKD3_k127_8468458_24 - - - - 0.000000000000000000000000000000000000000000000005494 182.0
HKD3_k127_8468458_25 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.0000000000000000000000000000000000000000000001427 195.0
HKD3_k127_8468458_26 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000286 141.0
HKD3_k127_8468458_28 PFAM Peptidase M48 - - - 0.00000000000000000000000000003011 132.0
HKD3_k127_8468458_29 Probable zinc-ribbon domain - - - 0.00000000000000000000000000005688 126.0
HKD3_k127_8468458_3 Belongs to the thiolase family K00626 - 2.3.1.9 1.094e-194 613.0
HKD3_k127_8468458_30 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.00000000000000000000000000157 112.0
HKD3_k127_8468458_31 - - - - 0.000000000000002447 85.0
HKD3_k127_8468458_32 PilZ domain - - - 0.0000000003117 68.0
HKD3_k127_8468458_33 - - - - 0.0000005674 56.0
HKD3_k127_8468458_34 Bacterial SH3 domain - - - 0.000003724 61.0
HKD3_k127_8468458_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 621.0
HKD3_k127_8468458_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 627.0
HKD3_k127_8468458_6 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 567.0
HKD3_k127_8468458_7 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 514.0
HKD3_k127_8468458_8 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 450.0
HKD3_k127_8468458_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 446.0
HKD3_k127_8473848_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.451e-267 850.0
HKD3_k127_8473848_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 439.0
HKD3_k127_8473848_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 373.0
HKD3_k127_8473848_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 367.0
HKD3_k127_8473848_4 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 379.0
HKD3_k127_8473848_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 347.0
HKD3_k127_8473848_6 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000007299 212.0
HKD3_k127_8473848_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000001974 222.0
HKD3_k127_8473848_9 HIT domain K02503 - - 0.0000000000000000000000000000000000000000000003007 169.0
HKD3_k127_8479993_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.221e-320 1034.0
HKD3_k127_8479993_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 4.217e-300 942.0
HKD3_k127_8479993_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 304.0
HKD3_k127_8479993_11 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004125 263.0
HKD3_k127_8479993_13 - - - - 0.000000000000000000000000000000000000000000000000000000426 196.0
HKD3_k127_8479993_15 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000002642 188.0
HKD3_k127_8479993_16 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000001564 185.0
HKD3_k127_8479993_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.405e-288 937.0
HKD3_k127_8479993_20 Helix-turn-helix domain - - - 0.000000000000000000000000007647 115.0
HKD3_k127_8479993_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 554.0
HKD3_k127_8479993_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 477.0
HKD3_k127_8479993_5 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 461.0
HKD3_k127_8479993_6 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 355.0
HKD3_k127_8479993_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 333.0
HKD3_k127_8479993_9 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 302.0
HKD3_k127_8481877_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1220.0
HKD3_k127_8481877_1 Participates in both transcription termination and antitermination K02600 - - 4.866e-250 775.0
HKD3_k127_8481877_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.035e-215 696.0
HKD3_k127_8481877_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 342.0
HKD3_k127_8481877_4 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000000000000000002871 172.0
HKD3_k127_8481877_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000098 173.0
HKD3_k127_8481877_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001249 163.0
HKD3_k127_8481877_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000187 125.0
HKD3_k127_8481877_8 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.000000000000000000000000001465 117.0
HKD3_k127_8487823_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000213 213.0
HKD3_k127_8487823_1 PilT protein domain protein - - - 0.00000000000000000000000000000000000000001507 162.0
HKD3_k127_8487823_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000002951 156.0
HKD3_k127_8487823_3 - - - - 0.000000002536 63.0
HKD3_k127_8487823_4 Psort location CytoplasmicMembrane, score - - - 0.000000283 63.0
HKD3_k127_8487823_5 - - - - 0.0000005005 59.0
HKD3_k127_8487823_6 - - - - 0.000004451 57.0
HKD3_k127_8487985_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0 1012.0
HKD3_k127_8487985_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 1.683e-204 639.0
HKD3_k127_8487985_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 480.0
HKD3_k127_8487985_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 342.0
HKD3_k127_8487985_4 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000006822 134.0
HKD3_k127_8487985_5 Redoxin - - - 0.00000003359 64.0
HKD3_k127_8493956_0 GAF domain - - - 7.981e-254 829.0
HKD3_k127_8493956_1 Selenocysteine-specific translation elongation factor K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 308.0
HKD3_k127_8494941_0 Carboxyl transferase domain - - - 4.34e-269 834.0
HKD3_k127_8494941_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.835e-226 708.0
HKD3_k127_8494941_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 297.0
HKD3_k127_8494941_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004229 291.0
HKD3_k127_8494941_12 methyltransferase activity K13613,K15677 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002595 282.0
HKD3_k127_8494941_13 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000002092 250.0
HKD3_k127_8494941_14 protein trimerization K15368 - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
HKD3_k127_8494941_15 PQQ enzyme repeat K17713 - - 0.00000006816 64.0
HKD3_k127_8494941_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.956e-218 680.0
HKD3_k127_8494941_3 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 594.0
HKD3_k127_8494941_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 460.0
HKD3_k127_8494941_6 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 458.0
HKD3_k127_8494941_7 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 488.0
HKD3_k127_8494941_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 366.0
HKD3_k127_8494941_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 330.0
HKD3_k127_8511770_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 318.0
HKD3_k127_8511770_1 PQQ enzyme repeat K17713 - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HKD3_k127_8511770_2 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000000007228 192.0
HKD3_k127_8511770_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000003934 168.0
HKD3_k127_8525402_0 Peptidase family M3 K01392 - 3.4.24.15 2e-323 1000.0
HKD3_k127_8525402_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 452.0
HKD3_k127_8525402_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 396.0
HKD3_k127_8525402_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 413.0
HKD3_k127_8525402_4 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000008699 216.0
HKD3_k127_8525402_5 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00007774 45.0
HKD3_k127_8545083_0 asparagine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007331 259.0
HKD3_k127_8545083_2 2'-5' RNA ligase - - - 0.0000009867 61.0
HKD3_k127_8545083_3 Acetyltransferase (GNAT) domain - - - 0.000006814 60.0
HKD3_k127_8547137_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.042e-246 766.0
HKD3_k127_8547137_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 544.0
HKD3_k127_8547137_10 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000001706 142.0
HKD3_k127_8547137_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 518.0
HKD3_k127_8547137_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 460.0
HKD3_k127_8547137_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 306.0
HKD3_k127_8547137_5 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 315.0
HKD3_k127_8547137_6 Inward rectifier potassium channel K08715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003046 301.0
HKD3_k127_8547137_7 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HKD3_k127_8547137_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000005152 187.0
HKD3_k127_8547137_9 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000005858 151.0
HKD3_k127_8555142_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 4.199e-194 610.0
HKD3_k127_8555142_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 489.0
HKD3_k127_8555142_10 periplasmic or secreted lipoprotein - - - 0.0000000004025 65.0
HKD3_k127_8555142_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 398.0
HKD3_k127_8555142_3 PFAM amidohydrolase K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 383.0
HKD3_k127_8555142_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 377.0
HKD3_k127_8555142_5 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 352.0
HKD3_k127_8555142_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 338.0
HKD3_k127_8555142_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 343.0
HKD3_k127_8555142_8 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002233 266.0
HKD3_k127_8555142_9 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000000000000000000000000009139 198.0
HKD3_k127_8583703_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.074e-301 935.0
HKD3_k127_8583703_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 1.203e-250 782.0
HKD3_k127_8583703_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 1.182e-199 632.0
HKD3_k127_8583703_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 583.0
HKD3_k127_8583703_4 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 391.0
HKD3_k127_8583703_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 370.0
HKD3_k127_8594743_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 347.0
HKD3_k127_8594743_1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003279 249.0
HKD3_k127_8594743_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000003022 222.0
HKD3_k127_8594743_3 TPR repeat - - - 0.000000000000000000000159 113.0
HKD3_k127_8597217_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.002e-296 923.0
HKD3_k127_8597217_1 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 400.0
HKD3_k127_8597217_2 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000033 209.0
HKD3_k127_8618979_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.301e-211 670.0
HKD3_k127_8618979_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 491.0
HKD3_k127_8618979_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 384.0
HKD3_k127_8618979_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000000000000001065 195.0
HKD3_k127_8618979_4 RDD family K18481 - - 0.0000000000000000000000000000000000000000000995 168.0
HKD3_k127_8621837_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1025.0
HKD3_k127_8621837_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.113e-213 672.0
HKD3_k127_8621837_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000001479 242.0
HKD3_k127_8621837_12 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000373 235.0
HKD3_k127_8621837_14 transcriptional regulator K09017,K18301 - - 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
HKD3_k127_8621837_15 Endonuclease V K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000003512 206.0
HKD3_k127_8621837_16 Cytochrome c - - - 0.000000000000000000000000000000000000000000001885 174.0
HKD3_k127_8621837_17 - - - - 0.000000000000000000000001262 115.0
HKD3_k127_8621837_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 569.0
HKD3_k127_8621837_3 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 564.0
HKD3_k127_8621837_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 563.0
HKD3_k127_8621837_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 517.0
HKD3_k127_8621837_6 Uracil phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 383.0
HKD3_k127_8621837_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 368.0
HKD3_k127_8621837_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 382.0
HKD3_k127_8621837_9 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 311.0
HKD3_k127_8622902_0 PFAM PHP domain protein K02347,K04477 - - 2.528e-244 767.0
HKD3_k127_8622902_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 578.0
HKD3_k127_8622902_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000001429 68.0
HKD3_k127_8622902_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 386.0
HKD3_k127_8622902_3 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 321.0
HKD3_k127_8622902_4 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 323.0
HKD3_k127_8622902_5 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004922 233.0
HKD3_k127_8622902_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000003322 205.0
HKD3_k127_8622902_7 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000002143 201.0
HKD3_k127_8622902_8 Universal stress protein - - - 0.0000000000000000000000000000000000000004986 153.0
HKD3_k127_8622902_9 Nitroreductase family - - - 0.0000000000000000000000000000000003219 146.0
HKD3_k127_8669004_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 538.0
HKD3_k127_8669004_1 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 375.0
HKD3_k127_8669004_2 - - - - 0.0000000000000000000000000001447 119.0
HKD3_k127_8669004_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.00000000000000000002331 106.0
HKD3_k127_8685492_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0 1245.0
HKD3_k127_8685492_1 Malate synthase K01638 - 2.3.3.9 0.0 1229.0
HKD3_k127_8685492_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004539 267.0
HKD3_k127_8685492_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006389 232.0
HKD3_k127_8685492_12 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000000009694 216.0
HKD3_k127_8685492_13 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000271 220.0
HKD3_k127_8685492_14 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000001526 203.0
HKD3_k127_8685492_15 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000001048 203.0
HKD3_k127_8685492_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000006109 182.0
HKD3_k127_8685492_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000002229 161.0
HKD3_k127_8685492_18 cold-shock protein K03704 - - 0.000000000000000000000000000000003716 135.0
HKD3_k127_8685492_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1183.0
HKD3_k127_8685492_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000001173 62.0
HKD3_k127_8685492_3 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 465.0
HKD3_k127_8685492_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 458.0
HKD3_k127_8685492_5 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 413.0
HKD3_k127_8685492_6 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 368.0
HKD3_k127_8685492_7 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 358.0
HKD3_k127_8685492_8 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 337.0
HKD3_k127_8685492_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
HKD3_k127_8691494_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 520.0
HKD3_k127_8691494_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 356.0
HKD3_k127_8691494_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000001175 213.0
HKD3_k127_8691494_5 Putative zinc-finger - - - 0.0000006044 60.0
HKD3_k127_8701284_0 acetyl-CoA carboxylase, biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.551e-196 620.0
HKD3_k127_8701284_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 569.0
HKD3_k127_8701284_2 Pfam:AHS1 K01941 - 6.3.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 477.0
HKD3_k127_8701284_3 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 408.0
HKD3_k127_8701284_4 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 392.0
HKD3_k127_8701284_5 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K11930 - - 0.000000000000000000000000000000000000000000000000000000000000000002865 245.0
HKD3_k127_8701284_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - 0.0000000000000000000000002814 107.0
HKD3_k127_8710060_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1199.0
HKD3_k127_8710060_1 Belongs to the ClpA ClpB family K03694 - - 1.136e-293 923.0
HKD3_k127_8710060_2 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 416.0
HKD3_k127_8710060_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000002165 136.0
HKD3_k127_8710060_4 - - - - 0.000006197 57.0
HKD3_k127_8713825_0 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 2.5e-322 1000.0
HKD3_k127_8713825_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 601.0
HKD3_k127_8713825_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001929 271.0
HKD3_k127_8713825_3 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000006312 214.0
HKD3_k127_8713825_4 repeat protein - - - 0.0000000000000000000000000000000000000000007456 166.0
HKD3_k127_8713825_5 Ribbon-helix-helix domain - - - 0.00000000000000000000000001984 109.0
HKD3_k127_8713825_6 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000002002 76.0
HKD3_k127_8758055_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1338.0
HKD3_k127_8758055_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.307e-200 643.0
HKD3_k127_8758055_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 407.0
HKD3_k127_8758055_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 373.0
HKD3_k127_8758055_12 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 359.0
HKD3_k127_8758055_13 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 366.0
HKD3_k127_8758055_14 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 349.0
HKD3_k127_8758055_15 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 347.0
HKD3_k127_8758055_16 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 285.0
HKD3_k127_8758055_17 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002456 255.0
HKD3_k127_8758055_18 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008016 235.0
HKD3_k127_8758055_19 - - - - 0.0000000000000000000000000008109 119.0
HKD3_k127_8758055_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 603.0
HKD3_k127_8758055_21 Class III cytochrome C family - - - 0.00000000000000000001453 94.0
HKD3_k127_8758055_23 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000626 79.0
HKD3_k127_8758055_24 histone H2A K63-linked ubiquitination K03220,K03832 - - 0.00000000005321 68.0
HKD3_k127_8758055_25 protein phosphatase 2C domain protein - - - 0.00000000007651 75.0
HKD3_k127_8758055_3 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 548.0
HKD3_k127_8758055_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 532.0
HKD3_k127_8758055_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 501.0
HKD3_k127_8758055_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 480.0
HKD3_k127_8758055_7 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 462.0
HKD3_k127_8758055_8 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 442.0
HKD3_k127_8758055_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 441.0
HKD3_k127_8783517_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1284.0
HKD3_k127_8783517_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1034.0
HKD3_k127_8783517_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 449.0
HKD3_k127_8783517_11 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 476.0
HKD3_k127_8783517_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 421.0
HKD3_k127_8783517_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
HKD3_k127_8783517_14 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 382.0
HKD3_k127_8783517_15 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 333.0
HKD3_k127_8783517_16 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 323.0
HKD3_k127_8783517_17 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 330.0
HKD3_k127_8783517_18 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
HKD3_k127_8783517_19 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001243 274.0
HKD3_k127_8783517_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.485e-251 782.0
HKD3_k127_8783517_20 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000153 228.0
HKD3_k127_8783517_23 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000002101 154.0
HKD3_k127_8783517_24 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00000000000000000000002322 108.0
HKD3_k127_8783517_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 1e-244 775.0
HKD3_k127_8783517_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 1.234e-233 731.0
HKD3_k127_8783517_5 Proton-conducting membrane transporter K12141 - - 3.873e-223 709.0
HKD3_k127_8783517_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 2.664e-214 676.0
HKD3_k127_8783517_7 Ribosomal protein S1-like RNA-binding domain K02945 - - 3.879e-212 671.0
HKD3_k127_8783517_8 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 600.0
HKD3_k127_8783517_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 563.0
HKD3_k127_8803054_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.396e-254 792.0
HKD3_k127_8803054_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.534e-225 708.0
HKD3_k127_8803054_10 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000005118 251.0
HKD3_k127_8803054_11 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000002713 201.0
HKD3_k127_8803054_12 cysteine protease - - - 0.000000000000000000000000000000000000000000000003076 174.0
HKD3_k127_8803054_13 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000001711 121.0
HKD3_k127_8803054_14 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000001559 64.0
HKD3_k127_8803054_2 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 9.005e-199 626.0
HKD3_k127_8803054_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 355.0
HKD3_k127_8803054_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
HKD3_k127_8803054_5 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005999 278.0
HKD3_k127_8803054_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005259 281.0
HKD3_k127_8803054_7 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001199 263.0
HKD3_k127_8803054_8 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002627 258.0
HKD3_k127_8803054_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006751 252.0
HKD3_k127_8828152_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1426.0
HKD3_k127_8828152_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 1.091e-218 698.0
HKD3_k127_8828152_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000001535 102.0
HKD3_k127_8828152_12 PFAM Cytochrome C - - - 0.0002451 48.0
HKD3_k127_8828152_2 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 587.0
HKD3_k127_8828152_3 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 537.0
HKD3_k127_8828152_5 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 284.0
HKD3_k127_8828152_6 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004874 257.0
HKD3_k127_8828152_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002425 269.0
HKD3_k127_8881982_0 Response regulator receiver - - - 3.043e-258 805.0
HKD3_k127_8881982_1 May be involved in recombinational repair of damaged DNA K03631 - - 6.362e-230 728.0
HKD3_k127_8881982_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 421.0
HKD3_k127_8881982_11 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979,K19714 - 1.1.3.48,2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 333.0
HKD3_k127_8881982_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 316.0
HKD3_k127_8881982_13 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 310.0
HKD3_k127_8881982_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 303.0
HKD3_k127_8881982_15 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001911 284.0
HKD3_k127_8881982_16 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 278.0
HKD3_k127_8881982_17 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 277.0
HKD3_k127_8881982_18 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008953 274.0
HKD3_k127_8881982_19 RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007551 278.0
HKD3_k127_8881982_2 AAA C-terminal domain K07478 - - 7.481e-227 708.0
HKD3_k127_8881982_20 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001123 240.0
HKD3_k127_8881982_21 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000001587 188.0
HKD3_k127_8881982_22 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.0000000000000000000000000000000000000000004334 172.0
HKD3_k127_8881982_23 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000002901 175.0
HKD3_k127_8881982_24 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000004989 141.0
HKD3_k127_8881982_25 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000007006 140.0
HKD3_k127_8881982_26 SNARE associated Golgi protein - - - 0.000000000000000000000000005133 124.0
HKD3_k127_8881982_27 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000002608 105.0
HKD3_k127_8881982_3 Histidine kinase A domain protein K02482 - 2.7.13.3 2.083e-215 680.0
HKD3_k127_8881982_4 Belongs to the D-alanine--D-alanine ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 613.0
HKD3_k127_8881982_5 PFAM Iron-containing alcohol dehydrogenase K19714 - 1.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 553.0
HKD3_k127_8881982_6 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 550.0
HKD3_k127_8881982_7 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 480.0
HKD3_k127_8881982_8 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 463.0
HKD3_k127_8881982_9 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 440.0
HKD3_k127_8930391_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1350.0
HKD3_k127_8930391_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 1.366e-210 664.0
HKD3_k127_8930391_2 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 583.0
HKD3_k127_8930391_3 Monosaccharide ABC transporter ATP-binding protein, CUT2 family K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 558.0
HKD3_k127_8930391_4 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 389.0
HKD3_k127_8930391_5 Periplasmic binding proteins and sugar binding domain of LacI family K11930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 348.0
HKD3_k127_8930391_6 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000001709 156.0
HKD3_k127_8930391_7 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.0000000000000000000000000000001841 127.0
HKD3_k127_8938519_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.752e-280 869.0
HKD3_k127_8938519_1 PFAM Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
HKD3_k127_8938519_2 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000002298 190.0
HKD3_k127_8959072_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 505.0
HKD3_k127_8959072_1 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000003198 145.0
HKD3_k127_8959072_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000002389 73.0
HKD3_k127_9012071_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 501.0
HKD3_k127_9012071_1 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 483.0
HKD3_k127_9012071_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 400.0
HKD3_k127_9012071_3 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 316.0
HKD3_k127_90880_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 8.852e-290 900.0
HKD3_k127_90880_1 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
HKD3_k127_90880_2 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 488.0
HKD3_k127_90880_3 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 464.0
HKD3_k127_90880_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 351.0
HKD3_k127_90880_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 354.0
HKD3_k127_90880_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 302.0
HKD3_k127_90880_7 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003916 284.0
HKD3_k127_90880_9 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.00000000000000000000000000000000000008441 162.0
HKD3_k127_9094671_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 602.0
HKD3_k127_9094671_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 422.0
HKD3_k127_9094671_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 377.0
HKD3_k127_9239326_0 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 1.813e-196 619.0
HKD3_k127_9239326_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 501.0
HKD3_k127_9239326_2 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 492.0
HKD3_k127_9239326_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 444.0
HKD3_k127_9261633_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 8.741e-235 743.0
HKD3_k127_9261633_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.363e-224 701.0
HKD3_k127_9261633_10 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 331.0
HKD3_k127_9261633_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 334.0
HKD3_k127_9261633_12 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008098 284.0
HKD3_k127_9261633_13 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 267.0
HKD3_k127_9261633_14 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 246.0
HKD3_k127_9261633_16 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000003071 220.0
HKD3_k127_9261633_17 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000001034 196.0
HKD3_k127_9261633_18 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000004626 133.0
HKD3_k127_9261633_19 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000418 123.0
HKD3_k127_9261633_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 620.0
HKD3_k127_9261633_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 583.0
HKD3_k127_9261633_4 lipopolysaccharide transport K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 572.0
HKD3_k127_9261633_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 531.0
HKD3_k127_9261633_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 489.0
HKD3_k127_9261633_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 501.0
HKD3_k127_9261633_8 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 484.0
HKD3_k127_9261633_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 365.0
HKD3_k127_9436645_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 7.837e-318 1009.0
HKD3_k127_9436645_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.158e-202 642.0
HKD3_k127_9436645_2 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 592.0
HKD3_k127_9436645_3 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 491.0
HKD3_k127_9436645_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 486.0
HKD3_k127_9436645_5 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 493.0
HKD3_k127_9436645_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016891,GO:0016893,GO:0016896,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000006586 222.0
HKD3_k127_9436645_7 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000005182 212.0
HKD3_k127_9436645_8 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000002617 207.0
HKD3_k127_9436645_9 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000005826 51.0
HKD3_k127_9439309_0 permease K03303 - - 0.0 1009.0
HKD3_k127_9439309_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 529.0
HKD3_k127_9439309_2 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 418.0
HKD3_k127_9439309_3 - - - - 0.0000000000000000000000000000000000000006736 164.0
HKD3_k127_9439309_4 cold-shock protein K03704 - - 0.0000000000000000000000000000000001005 134.0
HKD3_k127_9439309_5 FMN binding - - - 0.00000000000000000000000000000001954 141.0
HKD3_k127_9439309_6 Transcriptional regulator K04033 - - 0.0000000000000000000000000002081 131.0
HKD3_k127_9439309_7 TAP-like protein - - - 0.0000000000000000000000002814 107.0
HKD3_k127_9503577_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.362e-276 887.0
HKD3_k127_9503577_1 FtsX-like permease family - - - 6.599e-250 791.0
HKD3_k127_9503577_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 349.0
HKD3_k127_9503577_11 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 331.0
HKD3_k127_9503577_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 317.0
HKD3_k127_9503577_13 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 288.0
HKD3_k127_9503577_14 Cytochrome c K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002072 285.0
HKD3_k127_9503577_15 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000001631 212.0
HKD3_k127_9503577_16 Cysteine-rich CPXCG - - - 0.0000000000000000000000000007499 123.0
HKD3_k127_9503577_17 oxidase subunit - - - 0.000000000000000000000000001087 131.0
HKD3_k127_9503577_18 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000224 87.0
HKD3_k127_9503577_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 646.0
HKD3_k127_9503577_3 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 505.0
HKD3_k127_9503577_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 523.0
HKD3_k127_9503577_5 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 423.0
HKD3_k127_9503577_6 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HKD3_k127_9503577_7 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 387.0
HKD3_k127_9503577_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 370.0
HKD3_k127_9503577_9 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 346.0
HKD3_k127_950895_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 500.0
HKD3_k127_950895_1 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 411.0
HKD3_k127_950895_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 372.0
HKD3_k127_950895_3 nuclear chromosome segregation K13582,K21471 - - 0.00000000000000000000000000000000000000000000106 186.0
HKD3_k127_9517614_0 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 619.0
HKD3_k127_9517614_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 349.0
HKD3_k127_9517614_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 318.0
HKD3_k127_9517614_3 domain, Protein - - - 0.0000000000000000000000000000000000000000002008 178.0
HKD3_k127_9517614_4 proteolysis - - - 0.0000000000000000000000000000000000005102 149.0
HKD3_k127_9517614_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.000000000000000000000003435 109.0
HKD3_k127_9517614_7 - - - - 0.0000000008345 71.0
HKD3_k127_9657612_0 Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001455 276.0
HKD3_k127_9657612_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
HKD3_k127_9657612_10 Peptidase M15 - - - 0.0000000001785 68.0
HKD3_k127_9657612_11 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K04763 - - 0.000000002546 70.0
HKD3_k127_9657612_12 - - - - 0.000000006531 65.0
HKD3_k127_9657612_14 cellulase activity - - - 0.0000005867 62.0
HKD3_k127_9657612_15 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000008651 62.0
HKD3_k127_9657612_16 - - - - 0.000003044 58.0
HKD3_k127_9657612_17 Chaperone of endosialidase - - - 0.000005767 57.0
HKD3_k127_9657612_19 - - - - 0.0002207 45.0
HKD3_k127_9657612_2 phage Terminase large subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004334 258.0
HKD3_k127_9657612_20 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0007475 51.0
HKD3_k127_9657612_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000001004 244.0
HKD3_k127_9657612_4 DNA integration K14059 - - 0.000000000000000000000000000000000000000000000000000001066 207.0
HKD3_k127_9657612_5 - - - - 0.0000000000000000000000000000000000000000000000001114 197.0
HKD3_k127_9657612_8 ERF superfamily - - - 0.000000000001808 79.0