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Overview

ID MAG01835
Name HKD3_bin.12
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Syntrophia
Order Syntrophales
Family UBA4778
Genus JBDKTK01
Species
Assembly information
Completeness (%) 69.09
Contamination (%) 3.02
GC content (%) 57.0
N50 (bp) 5,629
Genome size (bp) 1,931,042

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1960

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1091197_0 photoreceptor activity K02007,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003449 269.0
HKD3_k127_1091197_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000007076 185.0
HKD3_k127_1091197_2 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000005059 151.0
HKD3_k127_1091197_3 KaiB K08481 - - 0.000000000000000000000000000000002284 133.0
HKD3_k127_1091197_4 KaiB K08481 - - 0.000000000000000000000000000000006807 128.0
HKD3_k127_1096100_0 Radical SAM K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000003801 254.0
HKD3_k127_1096100_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006484 218.0
HKD3_k127_1096100_2 catalyzes the formation of indole and pyruvate from tryptophan K01667 - 4.1.99.1 0.00000000000000000000000000000000003204 135.0
HKD3_k127_1096100_3 - - - - 0.000000000000000007295 84.0
HKD3_k127_1096100_4 Major Facilitator Superfamily - - - 0.0000000000001062 75.0
HKD3_k127_1096100_5 Protein of unknown function (DUF3795) - - - 0.00000000001252 64.0
HKD3_k127_1096100_6 Protein of unknown function (DUF3795) - - - 0.0000004165 51.0
HKD3_k127_1096542_0 acetyl-CoA hydrolase transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 589.0
HKD3_k127_1096542_1 nerve growth factor signaling pathway K08062,K21486 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0003712,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0007154,GO:0007165,GO:0007264,GO:0007265,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031625,GO:0031974,GO:0031981,GO:0032991,GO:0035556,GO:0042826,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0044087,GO:0044389,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045171,GO:0045893,GO:0045935,GO:0045944,GO:0048518,GO:0048522,GO:0050750,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070325,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000001499 105.0
HKD3_k127_1109211_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 1.458e-208 667.0
HKD3_k127_1109211_1 PFAM Acyl-CoA dehydrogenase K09456 - - 5.851e-196 629.0
HKD3_k127_1109211_2 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000005539 146.0
HKD3_k127_1109211_3 DRTGG domain - - - 0.000000000000000000000000000001577 125.0
HKD3_k127_1109211_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000001043 92.0
HKD3_k127_1200255_0 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 346.0
HKD3_k127_1200255_1 TIGR00268 family K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 317.0
HKD3_k127_1200255_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000002331 145.0
HKD3_k127_1200255_3 - - - - 0.0000000000000002915 87.0
HKD3_k127_1215138_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.55e-209 661.0
HKD3_k127_1215138_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 400.0
HKD3_k127_1215138_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 306.0
HKD3_k127_1215138_3 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 292.0
HKD3_k127_1245334_0 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 554.0
HKD3_k127_1245334_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 351.0
HKD3_k127_1245334_2 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000001556 191.0
HKD3_k127_1245334_3 cytochrome c - - - 0.00003259 46.0
HKD3_k127_1266089_0 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15469 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 376.0
HKD3_k127_1266089_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
HKD3_k127_1266089_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HKD3_k127_1266089_3 PFAM Acyl-CoA dehydrogenase K00249,K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11,1.3.8.7 0.000000000000000000000000000000000000000000000000000007371 191.0
HKD3_k127_1266244_0 PFAM Citrate transporter - - - 7.773e-209 657.0
HKD3_k127_1266244_1 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 541.0
HKD3_k127_1266244_2 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 549.0
HKD3_k127_1266244_3 paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 306.0
HKD3_k127_1266244_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000002703 70.0
HKD3_k127_1285277_0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 334.0
HKD3_k127_1285277_1 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 346.0
HKD3_k127_1285277_2 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001766 265.0
HKD3_k127_1285277_3 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000004979 267.0
HKD3_k127_1285277_4 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000005263 188.0
HKD3_k127_1285277_5 Subtilase family - - - 0.000000000000000000000000000000000000000000002309 173.0
HKD3_k127_1285277_6 - - - - 0.000000000000000000000027 101.0
HKD3_k127_1285277_7 - - - - 0.000000009491 58.0
HKD3_k127_1295143_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.572e-253 793.0
HKD3_k127_1295143_1 7TM-HD extracellular K07037 - - 6.923e-223 715.0
HKD3_k127_1295143_10 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000001227 179.0
HKD3_k127_1295143_11 PTS system K02795 - - 0.0000000000000000000000000000000000000000000000008434 182.0
HKD3_k127_1295143_12 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000008991 176.0
HKD3_k127_1295143_13 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000000001146 158.0
HKD3_k127_1295143_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000007099 156.0
HKD3_k127_1295143_15 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000001568 145.0
HKD3_k127_1295143_16 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000255 137.0
HKD3_k127_1295143_17 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000004852 139.0
HKD3_k127_1295143_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 524.0
HKD3_k127_1295143_3 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 512.0
HKD3_k127_1295143_4 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 479.0
HKD3_k127_1295143_5 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 468.0
HKD3_k127_1295143_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 457.0
HKD3_k127_1295143_7 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 445.0
HKD3_k127_1295143_8 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 300.0
HKD3_k127_1295143_9 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000002169 224.0
HKD3_k127_1309799_0 DHH family K07462 - - 2.965e-212 673.0
HKD3_k127_1309799_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 544.0
HKD3_k127_1309799_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 365.0
HKD3_k127_1309799_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 343.0
HKD3_k127_1309799_4 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 306.0
HKD3_k127_1309799_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000177 288.0
HKD3_k127_1309799_7 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000002057 49.0
HKD3_k127_1339324_0 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 334.0
HKD3_k127_1339509_0 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000000003643 183.0
HKD3_k127_1339509_1 PFAM Oxidoreductase, molybdopterin binding K07147 - - 0.0000000000000000000000000000000000000000002038 166.0
HKD3_k127_1339509_2 AsmA-like C-terminal region K07289 - - 0.0000000000000003764 90.0
HKD3_k127_1359409_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
HKD3_k127_1359409_1 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 340.0
HKD3_k127_1359409_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000005901 209.0
HKD3_k127_1359409_3 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000005694 194.0
HKD3_k127_1359409_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000000003879 162.0
HKD3_k127_1359409_5 Protein of unknown function (DUF3568) - - - 0.0000000000000000000002181 101.0
HKD3_k127_1373631_0 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000001503 218.0
HKD3_k127_1373631_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000006125 190.0
HKD3_k127_1373631_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000139 172.0
HKD3_k127_1373631_3 DRTGG domain - - - 0.00000000000000000000000000001635 121.0
HKD3_k127_1373631_4 Histidine kinase-like ATPase domain - - - 0.00000000000006467 72.0
HKD3_k127_1375446_0 peptidase S16 K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 525.0
HKD3_k127_1375446_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001654 237.0
HKD3_k127_1375446_2 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000000000000000000000001514 201.0
HKD3_k127_1379282_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 6.867e-220 696.0
HKD3_k127_1379282_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K05927,K18008 - 1.12.2.1,1.12.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 422.0
HKD3_k127_1379282_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 312.0
HKD3_k127_1379282_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004409 274.0
HKD3_k127_1386424_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.312e-291 915.0
HKD3_k127_1386424_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000002332 154.0
HKD3_k127_1388140_0 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 420.0
HKD3_k127_1388140_1 Psort location Cytoplasmic, score K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
HKD3_k127_1413722_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
HKD3_k127_1415926_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.934e-236 756.0
HKD3_k127_1415926_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.604e-211 671.0
HKD3_k127_1415926_10 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000023 130.0
HKD3_k127_1415926_11 Haemolytic - - - 0.00000000000000000001033 96.0
HKD3_k127_1415926_12 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000003583 51.0
HKD3_k127_1415926_13 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0003683 45.0
HKD3_k127_1415926_2 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 612.0
HKD3_k127_1415926_3 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 523.0
HKD3_k127_1415926_4 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 431.0
HKD3_k127_1415926_5 DnaJ molecular chaperone homology domain K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 392.0
HKD3_k127_1415926_6 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000003441 242.0
HKD3_k127_1415926_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000009595 193.0
HKD3_k127_1415926_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000001869 181.0
HKD3_k127_1415926_9 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000006634 145.0
HKD3_k127_1438441_0 PFAM cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 595.0
HKD3_k127_1438441_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 496.0
HKD3_k127_1438441_2 PFAM cytochrome bd ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
HKD3_k127_1438441_3 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000001973 123.0
HKD3_k127_1438599_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.132e-241 760.0
HKD3_k127_1438599_1 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 582.0
HKD3_k127_1438599_2 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 396.0
HKD3_k127_1438599_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003913 282.0
HKD3_k127_1438599_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000003445 228.0
HKD3_k127_1438599_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000003543 194.0
HKD3_k127_1438599_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000004659 145.0
HKD3_k127_145319_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1398.0
HKD3_k127_145319_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 8.758e-208 655.0
HKD3_k127_145319_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 447.0
HKD3_k127_145319_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 382.0
HKD3_k127_145319_4 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 375.0
HKD3_k127_145319_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 365.0
HKD3_k127_145319_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000005417 197.0
HKD3_k127_145319_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000005785 183.0
HKD3_k127_1467303_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 546.0
HKD3_k127_1467303_1 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 433.0
HKD3_k127_1467303_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 387.0
HKD3_k127_1467303_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 361.0
HKD3_k127_1467303_4 helix_turn_helix, Lux Regulon K02479 - - 0.0000000000000000000000000000000000000000000000003601 180.0
HKD3_k127_1469141_0 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
HKD3_k127_1469141_1 binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
HKD3_k127_1469141_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000716 203.0
HKD3_k127_1469141_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000003421 175.0
HKD3_k127_1469141_4 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000001049 175.0
HKD3_k127_1469141_5 COGs COG1487 nucleic acid-binding protein contains PIN domain K18828 - - 0.000000000000000000000000000004316 123.0
HKD3_k127_1469141_6 - - - - 0.0000000000002415 73.0
HKD3_k127_1469141_7 PFAM MarR family - - - 0.0000000008905 65.0
HKD3_k127_1469141_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0007442 43.0
HKD3_k127_1469644_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 329.0
HKD3_k127_1469644_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 276.0
HKD3_k127_1469644_2 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005451 255.0
HKD3_k127_1469644_3 YacP-like NYN domain K06962 - - 0.00000000000000000000000000000000008577 139.0
HKD3_k127_1469644_4 - - - - 0.0000000000000000000000000000002912 126.0
HKD3_k127_1469644_5 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000004514 99.0
HKD3_k127_1469644_6 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000001062 106.0
HKD3_k127_1544824_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.777e-255 794.0
HKD3_k127_1544824_1 Ferredoxin K17992 - 1.12.1.3 0.00000000000000000000000000000000000000000005628 163.0
HKD3_k127_1544824_2 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.0000000000000000002011 89.0
HKD3_k127_1549911_0 glycerone kinase activity K07030 - - 0.00000000000000000000000000000000000000000000000000002043 199.0
HKD3_k127_1549911_1 Tim44 - - - 0.00000000000000000000000000000000000000000000000004812 186.0
HKD3_k127_1549911_2 dehydratase - - - 0.0000000000000000000004997 100.0
HKD3_k127_1552130_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 364.0
HKD3_k127_1552130_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
HKD3_k127_1552130_2 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001954 272.0
HKD3_k127_1552130_3 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000001138 208.0
HKD3_k127_1552130_4 Putative heavy-metal chelation K09138 - - 0.00000000000000000000000000000000000000000000000001064 190.0
HKD3_k127_1552130_5 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000009578 162.0
HKD3_k127_1574133_0 CoA binding domain K01905,K22224 - 6.2.1.13 4.979e-247 782.0
HKD3_k127_1574133_1 COG2610 H gluconate symporter and related permeases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 415.0
HKD3_k127_1574133_2 PAS modulated sigma54 specific transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 411.0
HKD3_k127_1574133_3 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 389.0
HKD3_k127_1574133_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 383.0
HKD3_k127_1574133_5 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.00005057 48.0
HKD3_k127_1592050_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 505.0
HKD3_k127_1592050_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HKD3_k127_1592050_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000006379 170.0
HKD3_k127_1604121_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 347.0
HKD3_k127_1604121_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 278.0
HKD3_k127_1604121_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000329 234.0
HKD3_k127_1604121_3 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000003722 180.0
HKD3_k127_1604121_4 Cytochrome b561 and DOMON domain-containing protein - GO:0000293,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016722,GO:0016723,GO:0055114 - 0.0007876 47.0
HKD3_k127_1621351_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.057e-278 859.0
HKD3_k127_1621351_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.213e-267 827.0
HKD3_k127_1621351_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 383.0
HKD3_k127_1621351_3 Alpha beta hydrolase K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000001308 237.0
HKD3_k127_1621351_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000008904 207.0
HKD3_k127_1621351_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000033 196.0
HKD3_k127_1621351_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000001814 156.0
HKD3_k127_1621351_7 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000003047 147.0
HKD3_k127_1621351_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000307 141.0
HKD3_k127_1628955_0 K+ potassium transporter K03549 - - 6.894e-319 987.0
HKD3_k127_1628955_1 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 370.0
HKD3_k127_1628955_2 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001234 259.0
HKD3_k127_1628955_3 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000005207 211.0
HKD3_k127_1628955_4 - - - - 0.000000000000000000000000000000005254 136.0
HKD3_k127_1639273_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 545.0
HKD3_k127_1639273_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 413.0
HKD3_k127_1639273_2 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
HKD3_k127_1639273_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000006067 227.0
HKD3_k127_1639273_4 Psort location Cytoplasmic, score K21011 - - 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HKD3_k127_1663063_0 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 3.787e-198 625.0
HKD3_k127_1663063_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 540.0
HKD3_k127_1663063_2 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 336.0
HKD3_k127_1663063_3 TatD related DNase K03424 - - 0.000000000000000000000000000000000001672 139.0
HKD3_k127_1669700_0 protein histidine kinase activity K02660,K03406,K07716,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000005651 211.0
HKD3_k127_1669700_1 - - - - 0.0003919 51.0
HKD3_k127_1681524_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1080.0
HKD3_k127_1681524_1 CoA-transferase family III K07749 - 2.8.3.16 1.899e-203 642.0
HKD3_k127_1681524_2 Iron-containing alcohol dehydrogenase K00001,K00100,K08325,K19955 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 439.0
HKD3_k127_1681524_3 Bacterial regulatory protein, Fis family K03721,K06714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 418.0
HKD3_k127_1681524_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 386.0
HKD3_k127_1681524_5 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000002128 225.0
HKD3_k127_1681524_6 acyl-CoA dehydrogenase - - - 0.0000000000000004251 85.0
HKD3_k127_1681524_7 protein import - - - 0.0000000000008795 81.0
HKD3_k127_168257_0 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 430.0
HKD3_k127_168257_1 Alpha beta hydrolase - - - 0.0004742 44.0
HKD3_k127_173870_0 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 447.0
HKD3_k127_173870_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 389.0
HKD3_k127_173870_2 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 390.0
HKD3_k127_173870_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 342.0
HKD3_k127_173870_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000002485 167.0
HKD3_k127_173870_5 4Fe-4S binding domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000781 135.0
HKD3_k127_173870_6 Tetratricopeptide repeat - - - 0.000000000000004884 78.0
HKD3_k127_173870_7 - - - - 0.0002009 46.0
HKD3_k127_177655_0 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 300.0
HKD3_k127_177655_1 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000001022 164.0
HKD3_k127_177655_2 Metallo-beta-lactamase superfamily - - - 0.0000001246 53.0
HKD3_k127_1790124_0 Psort location Periplasmic, score - - - 7.882e-204 650.0
HKD3_k127_1790124_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 468.0
HKD3_k127_1790124_2 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 349.0
HKD3_k127_1790124_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 315.0
HKD3_k127_1790124_4 PAS sensor protein - - - 0.0000000000000000000000000000000000000000005369 161.0
HKD3_k127_1790124_5 radical SAM domain protein K22318 - - 0.000000000000000000000000000000000000007477 147.0
HKD3_k127_1790124_6 amino acid transmembrane transporter activity K08869,K14209 - - 0.0003659 52.0
HKD3_k127_1797418_0 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 302.0
HKD3_k127_1797418_1 - - - - 0.0000000000000000000000000000000000000195 153.0
HKD3_k127_1797418_2 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000004241 94.0
HKD3_k127_1797418_3 Hit family K02503 - - 0.00000000000000000001735 91.0
HKD3_k127_1812945_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 378.0
HKD3_k127_1812945_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 319.0
HKD3_k127_1812945_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000003719 203.0
HKD3_k127_1812945_3 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000001007 161.0
HKD3_k127_1812945_4 - - - - 0.000000000505 61.0
HKD3_k127_1812945_5 - - - - 0.000000001068 65.0
HKD3_k127_1816645_0 FAD dependent oxidoreductase K00244 - 1.3.5.4 5.188e-209 661.0
HKD3_k127_1816645_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 515.0
HKD3_k127_1816645_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 439.0
HKD3_k127_1816645_3 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000002691 257.0
HKD3_k127_1816645_4 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000003219 173.0
HKD3_k127_1816645_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000008244 69.0
HKD3_k127_1816645_6 Sigma-54 interaction domain - - - 0.0000000001388 64.0
HKD3_k127_18288_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 377.0
HKD3_k127_18288_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 345.0
HKD3_k127_18288_2 PFAM CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000137 265.0
HKD3_k127_1835132_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 526.0
HKD3_k127_1835132_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 434.0
HKD3_k127_1835132_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
HKD3_k127_1835132_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003936 249.0
HKD3_k127_1835132_4 - - - - 0.000000000000001137 83.0
HKD3_k127_1835132_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000001584 62.0
HKD3_k127_1835132_6 MacB-like periplasmic core domain K02004 - - 0.00000002563 63.0
HKD3_k127_1835132_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00006219 47.0
HKD3_k127_1900699_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 602.0
HKD3_k127_1900699_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 342.0
HKD3_k127_1900699_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000001408 216.0
HKD3_k127_1923764_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 428.0
HKD3_k127_1923764_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000002272 62.0
HKD3_k127_1923764_2 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00001315 51.0
HKD3_k127_1942644_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
HKD3_k127_1942644_1 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 257.0
HKD3_k127_1942644_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001833 252.0
HKD3_k127_1942644_3 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000006343 206.0
HKD3_k127_1942644_4 PFAM von Willebrand factor type A domain K03286 - - 0.000006202 54.0
HKD3_k127_196330_0 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.0000000000000000000000000000000000000000000000000000000000000002368 232.0
HKD3_k127_196330_1 40-residue YVTN family beta-propeller repeat - - - 0.0000004044 62.0
HKD3_k127_196330_2 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0001124 53.0
HKD3_k127_196569_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 500.0
HKD3_k127_196569_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000001032 226.0
HKD3_k127_196569_2 MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000007544 184.0
HKD3_k127_196569_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000009141 154.0
HKD3_k127_1996607_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 441.0
HKD3_k127_2023042_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 606.0
HKD3_k127_2023042_1 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 582.0
HKD3_k127_2023042_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 404.0
HKD3_k127_2023042_3 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000000000000000000000000000000000001297 233.0
HKD3_k127_2023042_4 - - - - 0.00000001208 60.0
HKD3_k127_2108073_0 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 612.0
HKD3_k127_216112_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 604.0
HKD3_k127_216112_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 360.0
HKD3_k127_240686_0 peptidoglycan-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 288.0
HKD3_k127_240686_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005892 284.0
HKD3_k127_240686_2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000004537 104.0
HKD3_k127_240686_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.0006317 43.0
HKD3_k127_2418853_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 579.0
HKD3_k127_2418853_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 402.0
HKD3_k127_2418853_10 DGC domain protein - - - 0.000000000000000000000002097 107.0
HKD3_k127_2418853_11 Thioredoxin domain - - - 0.000000000000000000000002885 103.0
HKD3_k127_2418853_12 Thioredoxin domain - - - 0.00000000000000000000003748 101.0
HKD3_k127_2418853_13 LPP20 lipoprotein - - - 0.000000000000000002188 96.0
HKD3_k127_2418853_14 - - - - 0.00000000000000002249 84.0
HKD3_k127_2418853_16 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000001318 74.0
HKD3_k127_2418853_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.00004244 52.0
HKD3_k127_2418853_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002637 256.0
HKD3_k127_2418853_4 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000005869 244.0
HKD3_k127_2418853_5 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000004357 190.0
HKD3_k127_2418853_6 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000006342 187.0
HKD3_k127_2418853_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000004717 171.0
HKD3_k127_2418853_8 regulatory protein, arsR K03892 - - 0.00000000000000000000000000000000002258 138.0
HKD3_k127_2418853_9 dihydromethanopterin reductase activity - - - 0.00000000000000000000000000001303 120.0
HKD3_k127_2425474_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1031.0
HKD3_k127_2425474_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.912e-222 700.0
HKD3_k127_2425474_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000012 203.0
HKD3_k127_2425474_11 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000002349 189.0
HKD3_k127_2425474_12 Thioredoxin K03673 - - 0.0000000000000000000000000000000000000000003774 164.0
HKD3_k127_2425474_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000000212 161.0
HKD3_k127_2425474_14 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000001081 152.0
HKD3_k127_2425474_15 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000000000000000000000000009448 146.0
HKD3_k127_2425474_17 TIGRFAM F0F1-ATPase subunit K02116 - - 0.0000000000000000000000000000000001959 136.0
HKD3_k127_2425474_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000004743 132.0
HKD3_k127_2425474_19 Papain family cysteine protease - - - 0.0000000000000000004725 93.0
HKD3_k127_2425474_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.266e-220 691.0
HKD3_k127_2425474_20 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000003202 76.0
HKD3_k127_2425474_21 N-ATPase, AtpR subunit - - - 0.000000000008764 70.0
HKD3_k127_2425474_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 352.0
HKD3_k127_2425474_4 Bacterial regulatory protein, Fis family K02481,K07714 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 340.0
HKD3_k127_2425474_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
HKD3_k127_2425474_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 326.0
HKD3_k127_2425474_7 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 297.0
HKD3_k127_2425474_8 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000171 225.0
HKD3_k127_2425474_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000007943 231.0
HKD3_k127_2429084_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.617e-213 670.0
HKD3_k127_2429084_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
HKD3_k127_2432843_0 Acetyl-CoA hydrolase transferase N-terminal domain - - - 2.185e-244 769.0
HKD3_k127_2432843_1 WD domain, G-beta repeat - GO:0002244,GO:0002376,GO:0002520,GO:0007275,GO:0008150,GO:0009987,GO:0030097,GO:0030154,GO:0032501,GO:0032502,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869 - 0.00000000000000000000000000000000000000000000000008233 190.0
HKD3_k127_2432843_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000003369 119.0
HKD3_k127_2432843_3 KH domain K06960 - - 0.00000004088 55.0
HKD3_k127_2464522_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.524e-231 724.0
HKD3_k127_2464522_1 Protein of unknown function K09800 - - 0.0000000002084 74.0
HKD3_k127_2495512_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.733e-249 778.0
HKD3_k127_2495512_1 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 505.0
HKD3_k127_2495512_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 310.0
HKD3_k127_2495512_3 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 309.0
HKD3_k127_2495512_4 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000263 274.0
HKD3_k127_2495512_5 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004471 282.0
HKD3_k127_2495512_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 257.0
HKD3_k127_2495512_7 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000008306 156.0
HKD3_k127_2495512_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000004514 97.0
HKD3_k127_2498302_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.92e-256 801.0
HKD3_k127_2498302_1 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 340.0
HKD3_k127_2498302_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000001275 246.0
HKD3_k127_2498302_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000003958 89.0
HKD3_k127_2501958_0 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 569.0
HKD3_k127_2501958_1 acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 288.0
HKD3_k127_2501958_2 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001303 274.0
HKD3_k127_2501958_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009882 259.0
HKD3_k127_2501958_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000002034 181.0
HKD3_k127_2534987_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905 - 6.2.1.13 6.587e-213 676.0
HKD3_k127_2541469_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 477.0
HKD3_k127_2541469_1 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 306.0
HKD3_k127_2541469_3 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000002548 205.0
HKD3_k127_2541469_4 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000006158 186.0
HKD3_k127_2553599_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0 1098.0
HKD3_k127_2553599_1 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 293.0
HKD3_k127_2553599_2 endonuclease III K01142,K10773 - 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
HKD3_k127_2553599_3 Protein of unknown function (DUF1178) - - - 0.000000001435 59.0
HKD3_k127_2553695_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 1.501e-200 632.0
HKD3_k127_2553695_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 323.0
HKD3_k127_2553695_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 296.0
HKD3_k127_2553695_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005075 282.0
HKD3_k127_2553695_4 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000003603 177.0
HKD3_k127_2553695_5 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000006783 117.0
HKD3_k127_2553695_6 Phosphopantetheine attachment site K02078 - - 0.00000000000000000005986 92.0
HKD3_k127_2553695_7 PFAM Acyl-CoA dehydrogenase K00249,K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11,1.3.8.7 0.00000000004006 63.0
HKD3_k127_2553695_8 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000001375 61.0
HKD3_k127_2558553_0 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000001215 220.0
HKD3_k127_2558553_1 Fimbrial assembly family protein K02461 - - 0.000000000000000000000000000000000000000000000000000000005877 217.0
HKD3_k127_2558553_2 General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000004317 162.0
HKD3_k127_2558553_3 Type II secretion system (T2SS), protein M K02462 - - 0.0000000000000000000000003022 112.0
HKD3_k127_2558553_4 General secretion pathway protein C K02452 - - 0.0000000000000000000000006394 116.0
HKD3_k127_2558553_5 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000003396 95.0
HKD3_k127_2558553_6 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000008479 76.0
HKD3_k127_2558553_7 Prokaryotic N-terminal methylation motif K02459 - - 0.000000005534 65.0
HKD3_k127_2558553_8 Type II secretory pathway, component ExeA K02450 - - 0.000000005986 59.0
HKD3_k127_2558553_9 - - - - 0.0008269 51.0
HKD3_k127_2571571_0 Chase2 domain K01768,K07814 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 406.0
HKD3_k127_2571571_1 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 338.0
HKD3_k127_2571571_2 chlorophyll binding K03286 - - 0.0000000000000000000000000000000003568 140.0
HKD3_k127_2571571_3 PFAM FecR protein - - - 0.0000000000000000000000000004516 119.0
HKD3_k127_2576270_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.501e-205 651.0
HKD3_k127_2576270_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.628e-199 630.0
HKD3_k127_2576270_2 FAD dependent oxidoreductase K00116,K15736 - 1.1.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 326.0
HKD3_k127_2594816_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 327.0
HKD3_k127_2594816_1 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005397 255.0
HKD3_k127_2594816_2 - - - - 0.000000000000000000000000000000000472 135.0
HKD3_k127_2594816_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000944 119.0
HKD3_k127_2596158_0 Pfam:T6SS_VipB K11896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 599.0
HKD3_k127_2596158_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 407.0
HKD3_k127_2596158_2 Pfam:T6SS_VasB K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000498 246.0
HKD3_k127_2596158_3 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000001594 204.0
HKD3_k127_2596158_4 TIGRFAM Type VI secretion system, lysozyme-related K11905 - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD3_k127_2596158_5 - - - - 0.00000000000000000000000000000000000000000002674 177.0
HKD3_k127_261882_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 509.0
HKD3_k127_261882_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 447.0
HKD3_k127_261882_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000004437 194.0
HKD3_k127_261882_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000244 107.0
HKD3_k127_2623944_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 604.0
HKD3_k127_2644266_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 9.765e-270 835.0
HKD3_k127_2644266_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 307.0
HKD3_k127_2644266_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000007104 180.0
HKD3_k127_2687503_0 Domain of unknown function (DUF1846) - - - 4.614e-266 826.0
HKD3_k127_2687503_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 469.0
HKD3_k127_2687503_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 355.0
HKD3_k127_2687503_3 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001182 245.0
HKD3_k127_2687503_4 Putative stress-induced transcription regulator - - - 0.00000000000000000000000000000001463 133.0
HKD3_k127_2687503_5 PFAM Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000001652 133.0
HKD3_k127_2687503_6 - - - - 0.00000000000000003935 82.0
HKD3_k127_2691418_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.244e-195 619.0
HKD3_k127_2691418_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
HKD3_k127_2691418_2 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.000000000000000000000000000000002376 134.0
HKD3_k127_2698926_0 Major facilitator Superfamily K08218 - - 8.171e-245 766.0
HKD3_k127_2698926_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 462.0
HKD3_k127_2698926_2 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 0.0000000000000000000000000000000000000000000000000000000000005597 218.0
HKD3_k127_2721068_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 9.147e-227 716.0
HKD3_k127_2721068_1 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006496 261.0
HKD3_k127_2721068_2 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000004394 199.0
HKD3_k127_2721068_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000396 182.0
HKD3_k127_2721068_4 Ribonuclease H K03469 - 3.1.26.4 0.000000000000000000000000000000003 133.0
HKD3_k127_2721068_5 - - - - 0.00000004085 55.0
HKD3_k127_2742311_0 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
HKD3_k127_2742311_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001706 251.0
HKD3_k127_2773062_0 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 5.08e-203 642.0
HKD3_k127_2773062_1 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000172 253.0
HKD3_k127_2787014_0 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003349 286.0
HKD3_k127_2787014_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002587 264.0
HKD3_k127_2787014_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000003758 160.0
HKD3_k127_2787014_3 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000006766 160.0
HKD3_k127_2787014_4 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000006053 113.0
HKD3_k127_2788302_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 7.288e-206 648.0
HKD3_k127_2788302_1 Smr domain - - - 0.000000000000000000000000000000000000000000000000000002447 198.0
HKD3_k127_2788302_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000267 133.0
HKD3_k127_2847340_0 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 339.0
HKD3_k127_2847340_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 331.0
HKD3_k127_2847340_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000289 232.0
HKD3_k127_2847340_3 - - - - 0.000003815 50.0
HKD3_k127_2864259_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 6.005e-308 960.0
HKD3_k127_2864259_1 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 391.0
HKD3_k127_2864259_2 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 341.0
HKD3_k127_2864259_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008646 248.0
HKD3_k127_2865347_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1e-270 848.0
HKD3_k127_2865347_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.753e-208 662.0
HKD3_k127_2865347_2 Osmosensitive K channel histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 492.0
HKD3_k127_2865347_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000002372 174.0
HKD3_k127_2865347_4 Amino acid permease K03294 - - 0.00000000168 59.0
HKD3_k127_2865347_5 amino acid K03294 - - 0.000000003353 60.0
HKD3_k127_2927439_0 ABC transporter K02013,K05776 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 332.0
HKD3_k127_2927439_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HKD3_k127_2927439_2 Aminotransferase class-V K00830,K00839 - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000004449 68.0
HKD3_k127_2933260_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000002486 223.0
HKD3_k127_2933260_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000003204 221.0
HKD3_k127_2933260_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.00000000000000000000000004793 108.0
HKD3_k127_296_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
HKD3_k127_296_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004409 274.0
HKD3_k127_296_2 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000009574 244.0
HKD3_k127_296_3 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000006018 156.0
HKD3_k127_3028886_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 419.0
HKD3_k127_3028886_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 279.0
HKD3_k127_3028886_2 PFAM ATP synthase I chain - - - 0.000000000000000002873 89.0
HKD3_k127_3152528_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 5.589e-255 800.0
HKD3_k127_3152528_1 FAD dependent oxidoreductase K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 406.0
HKD3_k127_3152528_2 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000001003 170.0
HKD3_k127_3152528_3 - - - - 0.000000000001022 76.0
HKD3_k127_3152528_4 Fe-S-cluster oxidoreductase K06940 - - 0.000000001237 66.0
HKD3_k127_3158034_0 Belongs to the transketolase family K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 558.0
HKD3_k127_3158034_1 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HKD3_k127_3183827_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 563.0
HKD3_k127_3183827_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000002111 76.0
HKD3_k127_3201288_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 460.0
HKD3_k127_3201288_1 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 449.0
HKD3_k127_3201288_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000179 100.0
HKD3_k127_3217381_0 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
HKD3_k127_3217381_1 Roadblock/LC7 domain - - - 0.000000000000000000000000000000003827 132.0
HKD3_k127_3217381_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000007145 98.0
HKD3_k127_3217381_3 - K08086 - - 0.0000000000000003147 91.0
HKD3_k127_3217381_4 PilZ domain - - - 0.000000000001614 72.0
HKD3_k127_3217381_5 3D domain protein - - - 0.00000001239 62.0
HKD3_k127_3299673_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
HKD3_k127_3299673_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.0000000000000000000000000000000000000000000006412 166.0
HKD3_k127_3299673_2 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000001617 121.0
HKD3_k127_3299673_3 Protein of unknown function (DUF3641) - - - 0.00000000000000000000002 102.0
HKD3_k127_3315563_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 414.0
HKD3_k127_3315563_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000576 192.0
HKD3_k127_3318166_0 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 4.317e-211 665.0
HKD3_k127_3318166_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 1.771e-204 644.0
HKD3_k127_3318166_2 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 601.0
HKD3_k127_3318166_3 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 586.0
HKD3_k127_3318166_4 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 353.0
HKD3_k127_3318166_5 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000009493 170.0
HKD3_k127_3438495_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 327.0
HKD3_k127_3438495_1 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000008018 214.0
HKD3_k127_3438495_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000006287 188.0
HKD3_k127_3438495_3 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000624 189.0
HKD3_k127_3438495_4 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.000000000000000000000000000000001964 132.0
HKD3_k127_3438495_5 Tetratricopeptide repeat - - - 0.000002134 56.0
HKD3_k127_3440607_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 579.0
HKD3_k127_3440607_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 325.0
HKD3_k127_3440607_2 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000002493 269.0
HKD3_k127_3440607_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000003261 246.0
HKD3_k127_3440607_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000001734 229.0
HKD3_k127_3440607_5 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000008232 111.0
HKD3_k127_3440607_6 Protein of unknown function (DUF1178) - - - 0.000000000000000001563 89.0
HKD3_k127_3440607_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000005388 78.0
HKD3_k127_3440607_8 - - - - 0.00002997 47.0
HKD3_k127_3442907_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
HKD3_k127_3442907_1 leucine-zipper of insertion element IS481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 402.0
HKD3_k127_3442907_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
HKD3_k127_3442907_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 294.0
HKD3_k127_3442907_4 PFAM Xanthine uracil vitamin C permease - - - 0.000000002705 58.0
HKD3_k127_3471835_0 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 587.0
HKD3_k127_3471835_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 463.0
HKD3_k127_352106_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 484.0
HKD3_k127_352106_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000009703 145.0
HKD3_k127_352106_2 protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000001804 138.0
HKD3_k127_352106_3 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000001689 97.0
HKD3_k127_352918_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 1.945e-217 688.0
HKD3_k127_352918_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 545.0
HKD3_k127_352918_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
HKD3_k127_352918_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 282.0
HKD3_k127_352918_4 lactate metabolic process K00113,K21834 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000415 267.0
HKD3_k127_352918_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000007216 68.0
HKD3_k127_3622325_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 485.0
HKD3_k127_3622325_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 419.0
HKD3_k127_3622325_10 MoaE protein K03635 - 2.8.1.12 0.00000000000000000006381 91.0
HKD3_k127_3622325_11 Protein of unknown function (DUF721) - - - 0.00000000000706 73.0
HKD3_k127_3622325_2 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 386.0
HKD3_k127_3622325_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 364.0
HKD3_k127_3622325_4 Radical_SAM C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
HKD3_k127_3622325_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
HKD3_k127_3622325_6 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 256.0
HKD3_k127_3622325_7 PFAM NIL domain - - - 0.00000000000000000000000000000000000000000000000000000000003135 208.0
HKD3_k127_3622325_8 - K07020,K18614 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.29 0.00000000000000000000000000000000000000000000000000001958 192.0
HKD3_k127_3622325_9 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000001746 118.0
HKD3_k127_3654560_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K05927,K18008 - 1.12.2.1,1.12.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 432.0
HKD3_k127_3654560_1 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
HKD3_k127_3654560_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000004419 209.0
HKD3_k127_3654560_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000006636 96.0
HKD3_k127_3654560_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000001803 81.0
HKD3_k127_3654560_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002916 71.0
HKD3_k127_3654560_6 PFAM ATP-binding region ATPase domain protein - - - 0.0001884 54.0
HKD3_k127_3670575_0 Iron hydrogenase small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 2.72e-304 940.0
HKD3_k127_3670575_1 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 2.156e-221 695.0
HKD3_k127_3670575_10 pfam nlp p60 - - - 0.0000000000000000000000000000000000000000000000000001536 203.0
HKD3_k127_3670575_11 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000003722 180.0
HKD3_k127_3670575_12 Transcriptional regulator - - - 0.00000000000000000000000000002886 118.0
HKD3_k127_3670575_13 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000006187 107.0
HKD3_k127_3670575_14 4Fe-4S binding domain - - - 0.0000000000003344 72.0
HKD3_k127_3670575_2 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 1.709e-215 681.0
HKD3_k127_3670575_3 PFAM fumarate lyase K01744 - 4.3.1.1 1.055e-198 629.0
HKD3_k127_3670575_4 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 597.0
HKD3_k127_3670575_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 571.0
HKD3_k127_3670575_6 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 415.0
HKD3_k127_3670575_7 Biotin and Thiamin Synthesis associated domain K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 391.0
HKD3_k127_3670575_8 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 334.0
HKD3_k127_3670575_9 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 327.0
HKD3_k127_3675344_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 480.0
HKD3_k127_3675344_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
HKD3_k127_3675344_3 Cache domain - - - 0.0000000000000000000000000000000000000001241 154.0
HKD3_k127_3675344_4 Putative regulatory protein - - - 0.0000000000000000002129 90.0
HKD3_k127_3675344_5 Outer membrane efflux protein - - - 0.000000000000000001621 87.0
HKD3_k127_3702247_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 430.0
HKD3_k127_3702247_1 Tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 384.0
HKD3_k127_3702247_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000002135 228.0
HKD3_k127_3702247_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000005299 131.0
HKD3_k127_3704419_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 524.0
HKD3_k127_3704419_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 389.0
HKD3_k127_3704419_10 acetyltransferase K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000001782 192.0
HKD3_k127_3704419_11 Transcriptional regulator K21903 - - 0.0000000000000000000000000000000001682 136.0
HKD3_k127_3704419_12 - - - - 0.00000000000000000000000000000002058 129.0
HKD3_k127_3704419_13 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000002772 120.0
HKD3_k127_3704419_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 376.0
HKD3_k127_3704419_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
HKD3_k127_3704419_4 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 293.0
HKD3_k127_3704419_5 TIGRFAM cysteine desulfurase family protein K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 287.0
HKD3_k127_3704419_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002309 289.0
HKD3_k127_3704419_7 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
HKD3_k127_3704419_8 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000005494 219.0
HKD3_k127_3704419_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000003533 213.0
HKD3_k127_3714908_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1117.0
HKD3_k127_3714908_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 376.0
HKD3_k127_3714908_2 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
HKD3_k127_3714908_3 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000001436 237.0
HKD3_k127_3714908_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000635 133.0
HKD3_k127_3714908_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000005258 118.0
HKD3_k127_3714908_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000002866 118.0
HKD3_k127_3714908_7 transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000103 73.0
HKD3_k127_3714908_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000001526 65.0
HKD3_k127_3715894_0 SMART Elongator protein 3 MiaB NifB K22227 - - 1.569e-195 617.0
HKD3_k127_3715894_1 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 407.0
HKD3_k127_3715894_2 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 368.0
HKD3_k127_3715894_3 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 355.0
HKD3_k127_3715894_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 334.0
HKD3_k127_3715894_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002526 268.0
HKD3_k127_3721744_0 FAD dependent oxidoreductase K00244 - 1.3.5.4 7.254e-216 682.0
HKD3_k127_3721744_1 PLD-like domain K06131 - - 4.771e-202 644.0
HKD3_k127_3721744_2 membrane protein required for spore maturation in B.subtilis K06374 - - 0.00000000000000000000000000000000000000000000000000000001157 201.0
HKD3_k127_3721744_3 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000005998 201.0
HKD3_k127_3721744_4 Phospholipase D. Active site motifs. - - - 0.0000000000000000000000000000000000000002378 156.0
HKD3_k127_3721744_5 Domain of unknown function (DUF4142) K08995 - - 0.0000000001611 69.0
HKD3_k127_3721744_6 denitrification pathway - - - 0.00005842 50.0
HKD3_k127_3728805_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1294.0
HKD3_k127_3728805_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 456.0
HKD3_k127_3728805_10 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000007338 203.0
HKD3_k127_3728805_11 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000004816 98.0
HKD3_k127_3728805_12 Glutaredoxin - - - 0.000000000009785 66.0
HKD3_k127_3728805_13 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000004826 59.0
HKD3_k127_3728805_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 433.0
HKD3_k127_3728805_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 383.0
HKD3_k127_3728805_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 328.0
HKD3_k127_3728805_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 312.0
HKD3_k127_3728805_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 306.0
HKD3_k127_3728805_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005137 259.0
HKD3_k127_3728805_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000881 254.0
HKD3_k127_3728805_9 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000003515 221.0
HKD3_k127_3746872_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 603.0
HKD3_k127_3746872_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 477.0
HKD3_k127_3746872_2 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 345.0
HKD3_k127_3746872_3 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
HKD3_k127_3746872_4 Fumarate K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001285 250.0
HKD3_k127_3751063_0 - - - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
HKD3_k127_3751063_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000001366 183.0
HKD3_k127_3751063_2 - - - - 0.0000000000000000000000000000000000000001042 153.0
HKD3_k127_3751775_0 Short chain fatty acid transporter K02106 - - 2.702e-210 663.0
HKD3_k127_3751775_1 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 514.0
HKD3_k127_3751775_2 - - - - 0.000000000000004112 77.0
HKD3_k127_3751775_3 Protein of unknown function (DUF493) K09158 - - 0.000000499 52.0
HKD3_k127_3753660_0 carbon starvation protein CstA K06200 - - 1.445e-309 957.0
HKD3_k127_3753660_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.662e-200 638.0
HKD3_k127_3753660_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000001142 249.0
HKD3_k127_3753660_11 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000005077 242.0
HKD3_k127_3753660_12 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000007637 208.0
HKD3_k127_3753660_13 HAD-superfamily hydrolase, subfamily IB K08966 - 3.1.3.87 0.00000000000000000000000000000000000000000000000000000001743 205.0
HKD3_k127_3753660_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000002299 200.0
HKD3_k127_3753660_15 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000001446 181.0
HKD3_k127_3753660_17 - - - - 0.000000000000000002422 88.0
HKD3_k127_3753660_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 537.0
HKD3_k127_3753660_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
HKD3_k127_3753660_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 470.0
HKD3_k127_3753660_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
HKD3_k127_3753660_6 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 385.0
HKD3_k127_3753660_7 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 316.0
HKD3_k127_3753660_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
HKD3_k127_3753660_9 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
HKD3_k127_3778304_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.759e-282 885.0
HKD3_k127_3778304_1 domain, Protein K12373 - 3.2.1.52 9.368e-210 666.0
HKD3_k127_3778304_2 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000005126 59.0
HKD3_k127_3781163_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 477.0
HKD3_k127_3781163_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 460.0
HKD3_k127_3781163_2 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000002251 195.0
HKD3_k127_3781163_3 PFAM GAF domain protein - - - 0.0000000000000000000000000000000000000000000000001865 183.0
HKD3_k127_3781163_4 sequence-specific DNA binding K07726 - - 0.0000000000000000000000000000000000000001013 152.0
HKD3_k127_3781163_5 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000000000000000000000000000005587 151.0
HKD3_k127_3789325_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 4.233e-226 718.0
HKD3_k127_3789325_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 591.0
HKD3_k127_3789325_10 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000001155 175.0
HKD3_k127_3789325_11 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000006604 155.0
HKD3_k127_3789325_12 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000001805 117.0
HKD3_k127_3789325_13 Essential cell division protein - - - 0.0000008195 57.0
HKD3_k127_3789325_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 518.0
HKD3_k127_3789325_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 515.0
HKD3_k127_3789325_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 454.0
HKD3_k127_3789325_5 elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
HKD3_k127_3789325_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 401.0
HKD3_k127_3789325_7 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 398.0
HKD3_k127_3789325_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 339.0
HKD3_k127_3789325_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006322 276.0
HKD3_k127_3791365_0 sigma54 specific transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 573.0
HKD3_k127_3791365_1 Belongs to the acetokinase family K00929 - 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 481.0
HKD3_k127_3791365_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000007024 91.0
HKD3_k127_3791365_3 PFAM Phosphate acetyl butaryl transferase K00634 - 2.3.1.19 0.0005693 43.0
HKD3_k127_379644_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 364.0
HKD3_k127_379644_1 protein complex oligomerization - - - 0.00000000000000000000000000000002696 135.0
HKD3_k127_379644_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000004945 61.0
HKD3_k127_379644_3 PFAM oxidoreductase molybdopterin binding - - - 0.0000001239 57.0
HKD3_k127_379644_4 YtxH-like protein - - - 0.0000001262 57.0
HKD3_k127_3814436_0 PFAM RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 385.0
HKD3_k127_3814436_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 329.0
HKD3_k127_3814436_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 323.0
HKD3_k127_3814436_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005665 295.0
HKD3_k127_3814436_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000852 237.0
HKD3_k127_3814436_5 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000001664 174.0
HKD3_k127_3814436_6 HD domain - - - 0.00000000000000000000000000000000000000000004702 181.0
HKD3_k127_3814436_7 Amidohydrolase K07045 - - 0.000000000000000000000002585 104.0
HKD3_k127_3817440_0 PFAM Pyruvate carboxyltransferase - - - 3.024e-316 978.0
HKD3_k127_3817440_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.148e-291 907.0
HKD3_k127_3817440_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 519.0
HKD3_k127_3817440_3 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 319.0
HKD3_k127_3817440_4 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000002159 116.0
HKD3_k127_3858516_0 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 415.0
HKD3_k127_3858516_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 366.0
HKD3_k127_3858516_2 Belongs to the thiolase family K00626,K07823 - 2.3.1.174,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000003066 245.0
HKD3_k127_3858516_3 YsiA-like protein, C-terminal region - - - 0.000000000000000000000000000002005 130.0
HKD3_k127_3858516_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000001381 100.0
HKD3_k127_3858516_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000001629 81.0
HKD3_k127_3867162_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 467.0
HKD3_k127_3867162_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 278.0
HKD3_k127_3867162_2 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000004079 200.0
HKD3_k127_3882039_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 439.0
HKD3_k127_3882039_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 396.0
HKD3_k127_3882039_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 352.0
HKD3_k127_3882039_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 294.0
HKD3_k127_3882039_4 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000371 144.0
HKD3_k127_3882039_5 - - - - 0.00000003243 59.0
HKD3_k127_3882039_6 transport system, periplasmic component - - - 0.00000004277 57.0
HKD3_k127_3894699_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 429.0
HKD3_k127_3894699_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 286.0
HKD3_k127_3894699_2 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000001558 118.0
HKD3_k127_3894699_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000001416 52.0
HKD3_k127_3902650_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 5.451e-316 986.0
HKD3_k127_3902650_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
HKD3_k127_3902650_2 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000005409 187.0
HKD3_k127_3902650_3 TonB C terminal K03832 - - 0.0000000000000000000164 100.0
HKD3_k127_3902650_4 Protein of unknown function (DUF3047) - - - 0.000000000003664 74.0
HKD3_k127_3902650_5 ABC transporter K02013 - 3.6.3.34 0.00000000003329 65.0
HKD3_k127_3910752_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 320.0
HKD3_k127_3910752_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
HKD3_k127_3910752_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
HKD3_k127_3910752_3 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000003087 220.0
HKD3_k127_3910752_4 ATPase activity K02013,K02028,K05776 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 0.000000000000000000000000000000000000001239 156.0
HKD3_k127_3910752_5 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000005606 150.0
HKD3_k127_3910752_6 peptidyl-tyrosine sulfation - - - 0.000004384 53.0
HKD3_k127_3916221_0 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 328.0
HKD3_k127_3916221_1 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 290.0
HKD3_k127_3916221_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000004119 148.0
HKD3_k127_3916221_3 SagB-type dehydrogenase domain protein - - - 0.000000000000000000000001059 106.0
HKD3_k127_392847_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 472.0
HKD3_k127_392847_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 340.0
HKD3_k127_392847_2 FeoA K04759 - - 0.00000000000000000000000000000000000000000000000000024 190.0
HKD3_k127_3949209_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 6.737e-268 831.0
HKD3_k127_3949209_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
HKD3_k127_3949209_2 FAD dependent oxidoreductase - - - 0.000000000000003412 77.0
HKD3_k127_3949209_3 Cytochrome c3 - - - 0.00000000001009 71.0
HKD3_k127_3953256_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.638e-248 782.0
HKD3_k127_3953256_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
HKD3_k127_3953256_2 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000000000000000000000001332 207.0
HKD3_k127_3953256_3 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000001794 113.0
HKD3_k127_3953256_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000001222 110.0
HKD3_k127_3953256_5 Methyltransferase type 11 - - - 0.0000000000000008133 88.0
HKD3_k127_3958536_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.768e-287 888.0
HKD3_k127_3958536_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.938e-263 825.0
HKD3_k127_3958536_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 569.0
HKD3_k127_3958536_3 type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 493.0
HKD3_k127_3958536_4 metal-dependent phosphohydrolase HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 454.0
HKD3_k127_3958536_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000217 291.0
HKD3_k127_3958536_6 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000001949 147.0
HKD3_k127_3958536_7 Nitroreductase family - - - 0.0000000000000001653 81.0
HKD3_k127_3958536_8 Thiamine pyrophosphate enzyme, central K01652 - 2.2.1.6 0.0000000000000005767 78.0
HKD3_k127_4014263_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.026e-260 809.0
HKD3_k127_4014263_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.3e-208 654.0
HKD3_k127_4014263_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 312.0
HKD3_k127_4014263_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000267 45.0
HKD3_k127_4030325_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 298.0
HKD3_k127_4030325_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000004835 162.0
HKD3_k127_4030325_2 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000001883 152.0
HKD3_k127_4030325_3 Outer membrane lipoprotein Slp family K07285 - - 0.00000000000000000000000000000000000006776 149.0
HKD3_k127_4030325_4 - - - - 0.00000000000000000004174 92.0
HKD3_k127_4036010_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 366.0
HKD3_k127_4036010_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000001809 219.0
HKD3_k127_4036010_2 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000000000000781 134.0
HKD3_k127_4039267_0 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
HKD3_k127_4039267_1 SPTR P52686 SDS degradation transcriptional activation protein - - - 0.00000000000000000000000000000000000002966 155.0
HKD3_k127_4039267_2 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000001989 117.0
HKD3_k127_4039267_3 - - - - 0.000000000000002484 78.0
HKD3_k127_4039267_4 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 0.0008002 42.0
HKD3_k127_4055847_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 413.0
HKD3_k127_4055847_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 374.0
HKD3_k127_4055847_2 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 340.0
HKD3_k127_4055847_3 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 290.0
HKD3_k127_4055847_4 Protein of unknown function (DUF2905) - - - 0.0000000000000000000001121 98.0
HKD3_k127_4055847_5 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0001116 51.0
HKD3_k127_4062833_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.319e-296 923.0
HKD3_k127_4062833_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 334.0
HKD3_k127_4062833_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
HKD3_k127_4062833_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000001235 185.0
HKD3_k127_4072618_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1101.0
HKD3_k127_4072618_1 acetyl-CoA hydrolase K18122 - - 8.963e-208 653.0
HKD3_k127_4072618_10 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000006107 54.0
HKD3_k127_4072618_2 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 438.0
HKD3_k127_4072618_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 366.0
HKD3_k127_4072618_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
HKD3_k127_4072618_5 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 329.0
HKD3_k127_4072618_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
HKD3_k127_4072618_9 Carboxylesterase family - - - 0.000000000000001284 81.0
HKD3_k127_4089669_0 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
HKD3_k127_4089669_1 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 320.0
HKD3_k127_4089669_2 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000025 266.0
HKD3_k127_4117275_0 metalloenzyme domain protein K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 560.0
HKD3_k127_4117275_1 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 515.0
HKD3_k127_4117275_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 407.0
HKD3_k127_4117275_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 288.0
HKD3_k127_4117275_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002975 279.0
HKD3_k127_4117275_5 Flavodoxin - - - 0.000000000000000000000002597 102.0
HKD3_k127_4166273_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 385.0
HKD3_k127_4166273_1 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005725 273.0
HKD3_k127_4166273_2 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
HKD3_k127_4166273_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000002445 231.0
HKD3_k127_4166273_4 - - - - 0.0000000000000000000000000000000000006195 152.0
HKD3_k127_4166273_5 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000005094 122.0
HKD3_k127_4183035_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.844e-212 670.0
HKD3_k127_4183035_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 555.0
HKD3_k127_4183035_2 NAD- dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 408.0
HKD3_k127_4183035_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 313.0
HKD3_k127_4183035_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000003648 142.0
HKD3_k127_4228790_0 Threonine synthase N terminus K01733 - 4.2.3.1 5.855e-212 666.0
HKD3_k127_4228790_1 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 325.0
HKD3_k127_4228790_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000004258 113.0
HKD3_k127_4240923_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 621.0
HKD3_k127_4240923_1 Biotin-lipoyl like K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
HKD3_k127_4240923_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003026 288.0
HKD3_k127_4240923_3 AcrB/AcrD/AcrF family K03296,K19594 - - 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
HKD3_k127_4252852_0 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 449.0
HKD3_k127_4252852_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 355.0
HKD3_k127_4252852_10 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000305 188.0
HKD3_k127_4252852_11 Histidine kinase - - - 0.000000000000000000000000000008278 136.0
HKD3_k127_4252852_12 Universal stress protein family - - - 0.000000000000000000000000001198 117.0
HKD3_k127_4252852_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HKD3_k127_4252852_3 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002665 267.0
HKD3_k127_4252852_4 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000001145 245.0
HKD3_k127_4252852_5 photoreceptor activity K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000003936 237.0
HKD3_k127_4252852_6 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
HKD3_k127_4252852_7 GTP-binding protein TypA K06207 - - 0.000000000000000000000000000000000000000000000000000000000002831 209.0
HKD3_k127_4252852_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000001033 213.0
HKD3_k127_4252852_9 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000000000009631 201.0
HKD3_k127_4265749_0 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 518.0
HKD3_k127_4265749_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000001248 141.0
HKD3_k127_4278513_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 399.0
HKD3_k127_4278513_1 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001248 290.0
HKD3_k127_4278513_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000003222 190.0
HKD3_k127_4278513_3 Protein of unknown function (DUF3343) - - - 0.0000000000000000000000000000000000000000000000000001537 190.0
HKD3_k127_4278513_4 mechanosensitive ion channel K16052 - - 0.00000000000000000001208 93.0
HKD3_k127_4278513_5 Cyclophilin-like K09143 - - 0.0000000000000000000125 96.0
HKD3_k127_4278513_6 Sulfurtransferase TusA K04085 - - 0.000000000000000002303 86.0
HKD3_k127_4313121_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 4.692e-273 848.0
HKD3_k127_4313121_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 491.0
HKD3_k127_4313121_2 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000004027 202.0
HKD3_k127_436840_0 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009317 281.0
HKD3_k127_436840_1 - - - - 0.0000000000000000000000000000000000000000000000000001634 188.0
HKD3_k127_436840_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000003153 145.0
HKD3_k127_436840_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000001525 143.0
HKD3_k127_436840_4 COG0437 Fe-S-cluster-containing hydrogenase components 1 K07307 - - 0.0000001812 54.0
HKD3_k127_4421261_0 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 525.0
HKD3_k127_4421261_1 domain, Protein K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 518.0
HKD3_k127_4421261_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 303.0
HKD3_k127_4421261_3 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000006678 151.0
HKD3_k127_4421261_4 Membrane - - - 0.00000000000000000000000001853 118.0
HKD3_k127_4421261_5 membrane - - - 0.00000000000000000000001712 112.0
HKD3_k127_4421261_6 Histidine kinase K07646 - 2.7.13.3 0.0000001398 62.0
HKD3_k127_4421261_7 Cytochrome c - - - 0.0000005659 60.0
HKD3_k127_4561263_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.595e-198 628.0
HKD3_k127_4561263_1 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 373.0
HKD3_k127_4561263_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 366.0
HKD3_k127_4561263_3 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001475 246.0
HKD3_k127_4561263_4 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002182 235.0
HKD3_k127_4561263_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000001556 194.0
HKD3_k127_4561263_6 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000002909 160.0
HKD3_k127_4561263_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000001125 116.0
HKD3_k127_4578479_0 Transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 295.0
HKD3_k127_4578479_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000001937 180.0
HKD3_k127_4578479_3 PFAM CBS domain K07182 - - 0.0000009634 57.0
HKD3_k127_459632_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 540.0
HKD3_k127_459632_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 387.0
HKD3_k127_459632_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 383.0
HKD3_k127_459632_3 Beta-lactamase superfamily domain K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000004473 163.0
HKD3_k127_4609200_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
HKD3_k127_4609200_1 - - - - 0.00000000000000000755 98.0
HKD3_k127_461434_0 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 475.0
HKD3_k127_461434_1 ABC transporter transmembrane region K12541 - - 0.000000000000000000000000000000000000000000000000006375 182.0
HKD3_k127_461434_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000002748 186.0
HKD3_k127_4626832_0 BadF BadG BcrA BcrD - - - 1.475e-199 633.0
HKD3_k127_4626832_1 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 306.0
HKD3_k127_4626832_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000226 243.0
HKD3_k127_4626832_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000005688 212.0
HKD3_k127_4663046_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 1.18e-204 651.0
HKD3_k127_4663046_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001656 238.0
HKD3_k127_4663046_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000007299 178.0
HKD3_k127_468576_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 7.003e-211 662.0
HKD3_k127_468576_1 drug transmembrane transporter activity K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 396.0
HKD3_k127_468576_2 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000002424 237.0
HKD3_k127_468576_3 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
HKD3_k127_468576_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000639 196.0
HKD3_k127_468576_5 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004759 185.0
HKD3_k127_468576_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001251 117.0
HKD3_k127_468576_7 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000003017 120.0
HKD3_k127_471285_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 999.0
HKD3_k127_471285_1 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 494.0
HKD3_k127_471285_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 377.0
HKD3_k127_471285_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 362.0
HKD3_k127_471285_4 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000009622 194.0
HKD3_k127_471285_5 PFAM aldo keto reductase K07079 - - 0.000000000000002613 80.0
HKD3_k127_471285_6 Regulatory protein, FmdB family - - - 0.000000009896 60.0
HKD3_k127_4780725_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1291.0
HKD3_k127_4780725_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000007204 100.0
HKD3_k127_4780725_2 SpoIID LytB domain protein K06381 - - 0.0000000000001284 72.0
HKD3_k127_478357_0 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
HKD3_k127_478357_1 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000001533 196.0
HKD3_k127_478357_2 4Fe-4S dicluster domain K03390,K22482 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000003421 150.0
HKD3_k127_478357_3 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000005383 114.0
HKD3_k127_478357_4 thiosulfate sulfurtransferase activity - - - 0.000003583 49.0
HKD3_k127_4804061_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 452.0
HKD3_k127_4804061_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 290.0
HKD3_k127_4804061_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000003317 219.0
HKD3_k127_4804061_3 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000003315 178.0
HKD3_k127_4832066_0 Receptor family ligand binding region K01999 - - 2.03e-202 639.0
HKD3_k127_4832066_1 PFAM Mammalian cell entry related K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 568.0
HKD3_k127_4832066_10 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000001047 209.0
HKD3_k127_4832066_11 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000000000000000000000000006796 167.0
HKD3_k127_4832066_12 - - - - 0.000000000000000000000000000000000000001284 154.0
HKD3_k127_4832066_13 SMART Cold shock protein K03704 - - 0.0000000000000000000000000002016 114.0
HKD3_k127_4832066_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 552.0
HKD3_k127_4832066_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 507.0
HKD3_k127_4832066_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 378.0
HKD3_k127_4832066_5 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 313.0
HKD3_k127_4832066_6 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002726 264.0
HKD3_k127_4832066_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002415 254.0
HKD3_k127_4832066_8 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000004857 228.0
HKD3_k127_4832066_9 PFAM Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000087 231.0
HKD3_k127_4839825_0 Domain of unknown function (DUF4410) - - - 0.000000000000000000000000000000000000000000000000000000000000005465 224.0
HKD3_k127_4839825_1 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000003132 119.0
HKD3_k127_4839825_2 - - - - 0.000000222 62.0
HKD3_k127_4839825_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0005125 48.0
HKD3_k127_4853661_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 3.495e-270 837.0
HKD3_k127_4853661_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001169 269.0
HKD3_k127_4853661_2 NifU domain-containing protein - - - 0.0000000000000001637 82.0
HKD3_k127_4853661_3 - - - - 0.000000000000000832 80.0
HKD3_k127_4873063_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 573.0
HKD3_k127_4873063_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
HKD3_k127_4873063_2 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002874 250.0
HKD3_k127_4873063_3 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002073 242.0
HKD3_k127_4873063_4 PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000009132 224.0
HKD3_k127_4873063_5 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.000703 42.0
HKD3_k127_4911449_0 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 407.0
HKD3_k127_4911449_1 HMGL-like - - - 0.0000000000000000000000000000000000000000000000000000034 192.0
HKD3_k127_4911449_2 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016020,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0071944,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000002637 171.0
HKD3_k127_4911449_3 HMGL-like - - - 0.000000000000000000000000002816 111.0
HKD3_k127_4911449_5 peroxiredoxin activity K03386,K03564 - 1.11.1.15 0.00000000000000533 76.0
HKD3_k127_4919191_0 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 358.0
HKD3_k127_4919191_1 Universal stress protein - - - 0.00000000000000000000000000000000000004659 153.0
HKD3_k127_4919191_2 MORN repeat protein - - - 0.0000000000000000000153 102.0
HKD3_k127_4919191_3 SEC-C Motif Domain Protein - - - 0.00000000000003883 85.0
HKD3_k127_4920669_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.173e-246 773.0
HKD3_k127_4920669_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
HKD3_k127_4920669_2 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000001764 160.0
HKD3_k127_4920669_3 AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000008134 70.0
HKD3_k127_4946786_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 551.0
HKD3_k127_4946786_1 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 339.0
HKD3_k127_4946786_2 Cyclic nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 287.0
HKD3_k127_4946786_3 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 276.0
HKD3_k127_4946786_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000002229 218.0
HKD3_k127_4946786_5 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000000000000000000001235 193.0
HKD3_k127_4946786_6 cellulose binding - - - 0.00000000000000000003651 106.0
HKD3_k127_4946786_7 - - - - 0.000000000000000005404 94.0
HKD3_k127_4954361_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 409.0
HKD3_k127_4954361_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
HKD3_k127_4954361_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000001766 133.0
HKD3_k127_4954361_3 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.0006739 50.0
HKD3_k127_4958696_0 BadF BadG BcrA BcrD - - - 3.422e-267 839.0
HKD3_k127_497973_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.742e-213 684.0
HKD3_k127_497973_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 294.0
HKD3_k127_497973_2 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000003553 179.0
HKD3_k127_4994028_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 591.0
HKD3_k127_4994028_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 335.0
HKD3_k127_4994028_2 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 330.0
HKD3_k127_4994028_3 Enoyl-CoA hydratase/isomerase K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000003048 217.0
HKD3_k127_4994028_4 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000008016 106.0
HKD3_k127_5021667_0 ABC transporter K06020 - 3.6.3.25 2.236e-275 852.0
HKD3_k127_5021667_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001283 247.0
HKD3_k127_5036229_0 Acyl-CoA dehydrogenase family member 10 K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000005924 100.0
HKD3_k127_5055087_0 Stage II sporulation K07315 - 3.1.3.3 1.109e-198 638.0
HKD3_k127_5055087_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 604.0
HKD3_k127_5055087_10 Transcriptional regulatory protein, C terminal K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000003268 237.0
HKD3_k127_5055087_11 metal cluster binding K06940 - - 0.0000000000000000000000000000000005819 133.0
HKD3_k127_5055087_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 454.0
HKD3_k127_5055087_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 394.0
HKD3_k127_5055087_4 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 381.0
HKD3_k127_5055087_5 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 373.0
HKD3_k127_5055087_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD3_k127_5055087_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 295.0
HKD3_k127_5055087_8 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 291.0
HKD3_k127_5055087_9 PhoQ Sensor K07640 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005353 267.0
HKD3_k127_5090743_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 3.098e-247 775.0
HKD3_k127_5090743_1 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 433.0
HKD3_k127_5094229_0 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 490.0
HKD3_k127_5094229_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000001618 194.0
HKD3_k127_5094229_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000003812 147.0
HKD3_k127_5136876_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 615.0
HKD3_k127_5136876_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 569.0
HKD3_k127_5136876_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 549.0
HKD3_k127_5136876_3 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 285.0
HKD3_k127_5136876_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003607 243.0
HKD3_k127_5136876_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000005895 205.0
HKD3_k127_5136876_6 ABC transporter K06020 - 3.6.3.25 0.000000000000000002042 84.0
HKD3_k127_5136876_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000394 66.0
HKD3_k127_5141097_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 531.0
HKD3_k127_5141097_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HKD3_k127_5141097_2 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 323.0
HKD3_k127_5141097_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
HKD3_k127_5141097_4 Transposase - - - 0.00000000000000000000000000000000000000000000000001108 186.0
HKD3_k127_5141097_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000005198 100.0
HKD3_k127_5141097_6 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000001864 94.0
HKD3_k127_5141097_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.00001929 46.0
HKD3_k127_5148110_0 Phospholipase, patatin family K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 288.0
HKD3_k127_5148110_1 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001233 271.0
HKD3_k127_5148110_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000004281 224.0
HKD3_k127_5148110_3 Biotin-requiring enzyme - - - 0.00000000000000000003724 91.0
HKD3_k127_5148110_4 gas vesicle protein - - - 0.0000000009504 64.0
HKD3_k127_517661_0 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 490.0
HKD3_k127_517661_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 360.0
HKD3_k127_517661_2 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000634 209.0
HKD3_k127_517661_3 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000002875 59.0
HKD3_k127_5203086_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 365.0
HKD3_k127_5203086_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002265 285.0
HKD3_k127_5203086_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000003112 255.0
HKD3_k127_5203086_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
HKD3_k127_5203086_4 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.000000000009702 70.0
HKD3_k127_5210020_0 Helicase associated domain (HA2) Add an annotation K03578,K03579 - 3.6.4.13 0.0 1238.0
HKD3_k127_5210020_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 546.0
HKD3_k127_5260885_0 ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 273.0
HKD3_k127_5260885_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000009742 230.0
HKD3_k127_5260885_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000358 226.0
HKD3_k127_5260885_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000832 129.0
HKD3_k127_5260885_4 Caspase domain - - - 0.000000000000000006597 91.0
HKD3_k127_5260885_5 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000007256 72.0
HKD3_k127_5272062_0 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 361.0
HKD3_k127_5272062_1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 323.0
HKD3_k127_5272062_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 303.0
HKD3_k127_5272062_3 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000002585 202.0
HKD3_k127_5272062_4 6-pyruvoyl tetrahydropterin synthase - - - 0.00000000000000000000000001012 113.0
HKD3_k127_5289476_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 311.0
HKD3_k127_5289476_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000001638 149.0
HKD3_k127_5289476_2 BPTI/Kunitz family of serine protease inhibitors. - - - 0.000000000002197 68.0
HKD3_k127_5313775_0 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 396.0
HKD3_k127_5313775_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 330.0
HKD3_k127_5313775_2 FeoA K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005097 253.0
HKD3_k127_5324038_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 588.0
HKD3_k127_5324038_1 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 486.0
HKD3_k127_5324038_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000008983 128.0
HKD3_k127_5324038_3 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000001295 123.0
HKD3_k127_5336101_0 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 362.0
HKD3_k127_5336101_1 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000002455 210.0
HKD3_k127_5336101_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000003702 162.0
HKD3_k127_5336101_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000001276 76.0
HKD3_k127_5366000_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 382.0
HKD3_k127_5366000_1 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000007906 187.0
HKD3_k127_5366000_2 nitroreductase - - - 0.00000000000000000000000000000000000000005728 156.0
HKD3_k127_5444086_0 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 514.0
HKD3_k127_5444086_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000001803 236.0
HKD3_k127_5444086_2 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.00000000000000000000000000000000000003679 144.0
HKD3_k127_5444086_3 - - - - 0.0000000000000000000000000000000000001629 143.0
HKD3_k127_5444086_4 antisigma factor binding K01425,K02066,K03090,K04749,K06378,K07122 GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.5.1.2 0.00000000000000000004431 94.0
HKD3_k127_5459966_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 432.0
HKD3_k127_5459966_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000001305 174.0
HKD3_k127_5459966_2 phosphate acetyltransferase K00634,K13788 - 2.3.1.19,2.3.1.8 0.000000000000000000000000003203 111.0
HKD3_k127_5475663_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 469.0
HKD3_k127_5475663_1 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000001783 207.0
HKD3_k127_5475663_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000001362 101.0
HKD3_k127_5475663_3 YtxH-like protein - - - 0.000000000000000002744 89.0
HKD3_k127_548119_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 351.0
HKD3_k127_548119_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 310.0
HKD3_k127_548119_2 GPR1/FUN34/yaaH family K07034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 257.0
HKD3_k127_5509356_0 protein kinase activity - - - 0.000000000000000000005376 101.0
HKD3_k127_5579015_0 AcrB/AcrD/AcrF family - - - 0.0 1573.0
HKD3_k127_5579015_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1500.0
HKD3_k127_5579015_2 Biotin-lipoyl like K03585,K07799,K18901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 319.0
HKD3_k127_5585577_0 PAN domain - - - 0.0000000000000000000000000000000000000000000000000000001504 205.0
HKD3_k127_5585577_1 acyl-coa hydrolase K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000008179 175.0
HKD3_k127_5585577_2 Alpha-L-arabinofuranosidase B (ABFB) domain K01193 - 3.2.1.26 0.00000000000000000000000000000000114 138.0
HKD3_k127_5585577_3 in signal transduction K08482 - - 0.0000000000000000005584 87.0
HKD3_k127_5585577_4 - - - - 0.0000000000002617 80.0
HKD3_k127_5585577_5 bacterial-type flagellum-dependent cell motility - - - 0.000000004388 64.0
HKD3_k127_5593133_0 PFAM ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
HKD3_k127_5593133_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 341.0
HKD3_k127_5593133_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000005138 231.0
HKD3_k127_5593133_3 Protein of unknown function (DUF1134) - - - 0.000000002929 60.0
HKD3_k127_5616286_0 Peptidase M16C associated K06972 - - 0.0 1110.0
HKD3_k127_5616286_1 General secretory system II protein E domain protein - - - 1.144e-319 994.0
HKD3_k127_5616286_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 565.0
HKD3_k127_5616286_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 512.0
HKD3_k127_5616286_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000231 293.0
HKD3_k127_5616286_5 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000427 74.0
HKD3_k127_5677720_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 426.0
HKD3_k127_5677720_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 332.0
HKD3_k127_5677720_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000001194 188.0
HKD3_k127_5677720_3 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000001205 168.0
HKD3_k127_5677720_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001422 137.0
HKD3_k127_5677720_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000002848 119.0
HKD3_k127_574435_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 305.0
HKD3_k127_574435_1 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000004142 218.0
HKD3_k127_574435_2 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000005916 184.0
HKD3_k127_574435_3 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000009118 95.0
HKD3_k127_5804393_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 519.0
HKD3_k127_5804393_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 316.0
HKD3_k127_5804393_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000004439 226.0
HKD3_k127_5804393_3 - - - - 0.000000000000000008327 85.0
HKD3_k127_5804393_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000648 78.0
HKD3_k127_598751_0 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 351.0
HKD3_k127_598751_1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001183 256.0
HKD3_k127_6045923_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.69e-314 974.0
HKD3_k127_6045923_1 Domain of unknown function (DUF4301) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 503.0
HKD3_k127_6045923_2 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 389.0
HKD3_k127_6045923_3 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 372.0
HKD3_k127_6045923_4 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 320.0
HKD3_k127_6045923_5 PFAM metal-dependent phosphohydrolase, HD sub domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 306.0
HKD3_k127_6045923_6 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000003356 235.0
HKD3_k127_6045923_7 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000002737 177.0
HKD3_k127_6045923_8 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000001957 140.0
HKD3_k127_6060111_0 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 375.0
HKD3_k127_6060111_1 - - - - 0.000000003839 64.0
HKD3_k127_6063817_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 336.0
HKD3_k127_6063817_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000002015 214.0
HKD3_k127_6063817_2 - - - - 0.00000000000000000000000000000000000000000000000000000000002934 216.0
HKD3_k127_6063817_3 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000001338 209.0
HKD3_k127_6063817_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000009154 132.0
HKD3_k127_6063817_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000001296 98.0
HKD3_k127_6063817_6 - - - - 0.000000000002818 69.0
HKD3_k127_6067374_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1005.0
HKD3_k127_6067374_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.185e-202 646.0
HKD3_k127_6067374_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 297.0
HKD3_k127_6067374_3 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000006039 117.0
HKD3_k127_6077349_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1023.0
HKD3_k127_6077349_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.335e-301 944.0
HKD3_k127_6077349_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000006671 142.0
HKD3_k127_6077349_11 - - - - 0.00000000000000000000000000003715 119.0
HKD3_k127_6077349_12 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000002254 117.0
HKD3_k127_6077349_13 PTS HPr component phosphorylation site K11189 - - 0.00000000000000000000000002175 115.0
HKD3_k127_6077349_14 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000003304 91.0
HKD3_k127_6077349_15 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000005034 71.0
HKD3_k127_6077349_16 GAF domain - - - 0.00000001568 56.0
HKD3_k127_6077349_17 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.000006925 54.0
HKD3_k127_6077349_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 8.591e-243 762.0
HKD3_k127_6077349_3 Bacterial regulatory protein, Fis family - - - 1.404e-195 618.0
HKD3_k127_6077349_4 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 635.0
HKD3_k127_6077349_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 480.0
HKD3_k127_6077349_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 452.0
HKD3_k127_6077349_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000000002985 237.0
HKD3_k127_6077349_8 system, mannose fructose sorbose family, IID component K02796 - - 0.000000000000000000000000000000000000000000000000000000002113 209.0
HKD3_k127_6077349_9 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000204 153.0
HKD3_k127_6092445_0 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 313.0
HKD3_k127_6092445_1 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 233.0
HKD3_k127_6092445_2 cog1234, metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000000000000000000000418 137.0
HKD3_k127_6118052_0 Sulfatase K01130 - 3.1.6.1 7.222e-252 784.0
HKD3_k127_6118052_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 454.0
HKD3_k127_6118052_2 phenylacetate-CoA ligase Coenzyme F390 synthetase-like protein K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 452.0
HKD3_k127_6118052_3 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000001428 145.0
HKD3_k127_6121813_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HKD3_k127_6121813_1 diguanylate cyclase - - - 0.00000000000000000000000000000004349 143.0
HKD3_k127_6124504_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 594.0
HKD3_k127_6124504_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000007068 163.0
HKD3_k127_6152561_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.638e-204 641.0
HKD3_k127_6152561_1 Indole-3-glycerol phosphate synthase K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000002409 265.0
HKD3_k127_6152561_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000003887 234.0
HKD3_k127_6152561_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000003422 222.0
HKD3_k127_6152561_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000001441 144.0
HKD3_k127_6152836_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 461.0
HKD3_k127_6152836_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 440.0
HKD3_k127_6152836_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 434.0
HKD3_k127_6152836_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 406.0
HKD3_k127_6152836_4 Bacterial extracellular solute-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 334.0
HKD3_k127_6152836_5 PFAM response regulator receiver K07657,K07659,K07664,K11329 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
HKD3_k127_6152836_6 PhoU domain K02039 - - 0.0000000000004241 69.0
HKD3_k127_6154078_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.014e-320 993.0
HKD3_k127_6154078_1 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000036 190.0
HKD3_k127_6179570_0 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000000000000000000000000001027 215.0
HKD3_k127_6179570_1 - - - - 0.00000000000000000000000000000000000000000000000000001045 192.0
HKD3_k127_6179570_2 - - - - 0.00000000000000000000000003259 111.0
HKD3_k127_6179570_3 Peptidase dimerisation domain - - - 0.0000000005986 61.0
HKD3_k127_6186109_0 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 8.151e-235 739.0
HKD3_k127_6186109_1 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 351.0
HKD3_k127_6186109_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 338.0
HKD3_k127_6186109_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
HKD3_k127_6186109_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000008039 214.0
HKD3_k127_6186109_5 COG2610 H gluconate symporter and related permeases - - - 0.0000000000000000000000000000000000000000000000001608 181.0
HKD3_k127_6186109_6 Putative MetA-pathway of phenol degradation - - - 0.000000000008322 71.0
HKD3_k127_6194448_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 471.0
HKD3_k127_6194448_1 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000001865 219.0
HKD3_k127_6229999_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 471.0
HKD3_k127_6229999_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 338.0
HKD3_k127_6229999_2 Electron transfer flavoprotein, beta K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009762 264.0
HKD3_k127_6229999_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000001855 203.0
HKD3_k127_6229999_4 - - - - 0.000000000000002531 81.0
HKD3_k127_6241297_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.673e-205 651.0
HKD3_k127_6241297_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 460.0
HKD3_k127_6241297_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000004817 99.0
HKD3_k127_6241297_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 382.0
HKD3_k127_6241297_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 388.0
HKD3_k127_6241297_4 Signal transduction histidine kinase, nitrogen specific - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 379.0
HKD3_k127_6241297_5 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 366.0
HKD3_k127_6241297_6 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000002605 242.0
HKD3_k127_6241297_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000001507 224.0
HKD3_k127_6241297_8 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000006459 116.0
HKD3_k127_6241297_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000002815 103.0
HKD3_k127_6249341_0 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 413.0
HKD3_k127_6249341_1 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 304.0
HKD3_k127_6249341_2 exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 297.0
HKD3_k127_6253067_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 475.0
HKD3_k127_6253067_1 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
HKD3_k127_6253067_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000001115 178.0
HKD3_k127_6253067_3 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000008775 125.0
HKD3_k127_6253067_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000756 66.0
HKD3_k127_6253067_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000001452 67.0
HKD3_k127_6282976_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.0 1742.0
HKD3_k127_6282976_1 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 610.0
HKD3_k127_6282976_10 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000001359 151.0
HKD3_k127_6282976_11 PFAM amino acid-binding ACT domain protein - - - 0.00000000001551 68.0
HKD3_k127_6282976_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 564.0
HKD3_k127_6282976_3 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 466.0
HKD3_k127_6282976_4 Iron-containing alcohol dehydrogenase K00001,K00100,K08325,K19955 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 407.0
HKD3_k127_6282976_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 312.0
HKD3_k127_6282976_6 Major facilitator superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 311.0
HKD3_k127_6282976_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
HKD3_k127_6282976_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000113 213.0
HKD3_k127_6282976_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000002089 160.0
HKD3_k127_6299185_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 362.0
HKD3_k127_6299185_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 307.0
HKD3_k127_6299185_2 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
HKD3_k127_6299185_3 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003977 284.0
HKD3_k127_6299185_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000001083 217.0
HKD3_k127_6299185_5 - - - - 0.0000000000000000000000000000000000004456 147.0
HKD3_k127_6299185_6 PFAM NifU-like domain - - - 0.000000000000000000000000000006247 119.0
HKD3_k127_6299185_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000003764 96.0
HKD3_k127_6299185_8 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000004493 88.0
HKD3_k127_6308817_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 5.311e-198 631.0
HKD3_k127_6308817_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
HKD3_k127_6308817_2 Thioesterase superfamily - - - 0.0000000000005915 75.0
HKD3_k127_632422_0 Protein export membrane protein K03296,K18138 - - 2.761e-301 931.0
HKD3_k127_632422_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002191 252.0
HKD3_k127_6325637_0 DNA polymerase K02347 - - 3.428e-212 673.0
HKD3_k127_6325637_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 440.0
HKD3_k127_6325637_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 414.0
HKD3_k127_6325637_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000002113 77.0
HKD3_k127_6333925_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 624.0
HKD3_k127_6333925_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000008446 196.0
HKD3_k127_6333925_2 Domain of unknown function (DUF4410) - - - 0.000000000000000000000000000000005493 134.0
HKD3_k127_6333925_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000001635 106.0
HKD3_k127_6333925_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000277 102.0
HKD3_k127_6333925_5 - - - - 0.000000000000004813 81.0
HKD3_k127_6333925_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000007233 68.0
HKD3_k127_6333925_7 Alkylmercury lyase - - - 0.00002461 49.0
HKD3_k127_6334521_0 HRDC domain K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003967 282.0
HKD3_k127_6334521_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
HKD3_k127_6334521_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000001541 239.0
HKD3_k127_6345859_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 544.0
HKD3_k127_6345859_1 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 338.0
HKD3_k127_6395485_0 Lipoprotein - - - 1.214e-205 658.0
HKD3_k127_6395485_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 514.0
HKD3_k127_6395485_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 332.0
HKD3_k127_6395485_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 322.0
HKD3_k127_6395485_4 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000001177 198.0
HKD3_k127_6395485_5 - - - - 0.0000000000000000000000000000000000001131 153.0
HKD3_k127_6441191_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0 1016.0
HKD3_k127_6441191_1 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 364.0
HKD3_k127_6441191_10 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000643 74.0
HKD3_k127_6441191_11 Fe-S-cluster oxidoreductase K06940 - - 0.0000023 58.0
HKD3_k127_6441191_2 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 325.0
HKD3_k127_6441191_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001237 269.0
HKD3_k127_6441191_4 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 256.0
HKD3_k127_6441191_5 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
HKD3_k127_6441191_6 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000001837 122.0
HKD3_k127_6441191_8 MatE K03327 - - 0.000000000000000000001554 98.0
HKD3_k127_6441191_9 - - - - 0.000000000002467 70.0
HKD3_k127_6450884_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 480.0
HKD3_k127_6450884_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 413.0
HKD3_k127_6450884_2 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000002135 185.0
HKD3_k127_6450884_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000002433 124.0
HKD3_k127_6450884_4 Putative regulatory protein - - - 0.000000005438 59.0
HKD3_k127_6450884_5 - - - - 0.0000004215 55.0
HKD3_k127_6450884_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.000007112 48.0
HKD3_k127_6450884_7 nucleotide-binding Protein - - - 0.00003033 53.0
HKD3_k127_6451727_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 6.092e-200 629.0
HKD3_k127_6451727_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000003524 123.0
HKD3_k127_6451727_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000002403 55.0
HKD3_k127_6467544_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000011 267.0
HKD3_k127_6467544_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001427 265.0
HKD3_k127_6467544_2 gamma-aminobutyrate metabolism dehydratase isomerase K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000003983 150.0
HKD3_k127_6467544_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000005573 146.0
HKD3_k127_6473252_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 304.0
HKD3_k127_6473252_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 292.0
HKD3_k127_6473252_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000001274 209.0
HKD3_k127_6473252_3 Sulphur transport K07112 - - 0.00000000000005954 71.0
HKD3_k127_6473252_4 Protein of unknown function (DUF2845) - - - 0.000001186 55.0
HKD3_k127_647808_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 7.83e-261 808.0
HKD3_k127_647808_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 438.0
HKD3_k127_647808_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
HKD3_k127_647808_3 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000004899 192.0
HKD3_k127_647808_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000002629 177.0
HKD3_k127_647808_5 Domain of unknown function (DUF374) K09778 - - 0.0000000000005972 70.0
HKD3_k127_647808_6 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000001051 67.0
HKD3_k127_6522470_0 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 468.0
HKD3_k127_6522470_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 328.0
HKD3_k127_6544294_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 408.0
HKD3_k127_6544294_1 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
HKD3_k127_6544294_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001239 270.0
HKD3_k127_6544294_3 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000521 203.0
HKD3_k127_6544294_4 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000007305 184.0
HKD3_k127_6548100_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000005159 205.0
HKD3_k127_6548100_1 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000000000000005572 153.0
HKD3_k127_6548100_2 Protein of unknown function (DUF465) K09794 - - 0.00000000000001464 76.0
HKD3_k127_6548100_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000001012 55.0
HKD3_k127_6559246_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.392e-303 953.0
HKD3_k127_6559246_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.387e-219 703.0
HKD3_k127_6559246_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000005752 128.0
HKD3_k127_6559246_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 600.0
HKD3_k127_6559246_3 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 416.0
HKD3_k127_6559246_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 318.0
HKD3_k127_6559246_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009779 281.0
HKD3_k127_6559246_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000003376 198.0
HKD3_k127_6559246_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001238 146.0
HKD3_k127_6559246_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000002804 139.0
HKD3_k127_6559246_9 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000001036 134.0
HKD3_k127_6604685_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.902e-228 711.0
HKD3_k127_6604685_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.628e-212 666.0
HKD3_k127_6604685_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.196e-209 656.0
HKD3_k127_6604685_3 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000073 277.0
HKD3_k127_6604685_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000333 241.0
HKD3_k127_6604685_5 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000001903 238.0
HKD3_k127_6604685_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
HKD3_k127_6604685_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000001232 181.0
HKD3_k127_6604685_8 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000006486 91.0
HKD3_k127_6627539_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 401.0
HKD3_k127_6627539_1 fumarate reductase, flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000001094 250.0
HKD3_k127_6648738_0 General secretory system II protein E domain protein - - - 4.969e-283 888.0
HKD3_k127_6648738_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 455.0
HKD3_k127_6648738_2 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002238 248.0
HKD3_k127_6648738_3 Redoxin - - - 0.000000000000000000000000005588 113.0
HKD3_k127_6648738_4 PilZ domain - - - 0.0000000000000000000009342 97.0
HKD3_k127_6648738_5 - - - - 0.000000000004664 71.0
HKD3_k127_6691718_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.196e-278 867.0
HKD3_k127_6691718_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 318.0
HKD3_k127_6701238_0 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 550.0
HKD3_k127_6701238_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 514.0
HKD3_k127_6701238_2 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 355.0
HKD3_k127_6701238_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000145 223.0
HKD3_k127_6701238_4 UvrD/REP helicase N-terminal domain K03582,K16898 - 3.1.11.5,3.6.4.12 0.00000000000000000000000000000000000000000000000002882 186.0
HKD3_k127_6701238_5 Glutaredoxin K03676 - - 0.00000000000001271 74.0
HKD3_k127_6701238_6 PFAM Peptidase family M23 - - - 0.00000003319 66.0
HKD3_k127_670692_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 590.0
HKD3_k127_670692_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003115 277.0
HKD3_k127_670692_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000006992 163.0
HKD3_k127_6750993_0 HI0933-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 327.0
HKD3_k127_6750993_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 296.0
HKD3_k127_6750993_2 - - - - 0.000000000000000000000000000000000000000000000000000000000771 204.0
HKD3_k127_675654_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2291.0
HKD3_k127_675654_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.865e-315 977.0
HKD3_k127_6896232_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1267.0
HKD3_k127_6896232_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 6.319e-196 619.0
HKD3_k127_6896232_10 DoxX - - - 0.00000000000000000000000001888 114.0
HKD3_k127_6896232_11 RecX family K03565 - - 0.000000000000000000003344 102.0
HKD3_k127_6896232_12 Prokaryotic N-terminal methylation motif - - - 0.000000000000001044 82.0
HKD3_k127_6896232_13 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000006715 79.0
HKD3_k127_6896232_14 Rhodanese Homology Domain - - - 0.000000000002903 73.0
HKD3_k127_6896232_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 533.0
HKD3_k127_6896232_3 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 463.0
HKD3_k127_6896232_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 445.0
HKD3_k127_6896232_5 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
HKD3_k127_6896232_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
HKD3_k127_6896232_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000176 174.0
HKD3_k127_6896232_8 LigT like Phosphoesterase K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000001118 166.0
HKD3_k127_6896232_9 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000002843 141.0
HKD3_k127_6970234_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 8.615e-209 656.0
HKD3_k127_6970234_1 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 529.0
HKD3_k127_6970234_2 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000636 195.0
HKD3_k127_6970234_3 Prokaryotic cytochrome b561 K03620 - - 0.0000000000000000000000000000000039 137.0
HKD3_k127_6970234_4 Heavy-metal resistance - - - 0.0000000000000000000000002265 113.0
HKD3_k127_7057320_0 Virulence factor BrkB K07058 - - 1.961e-196 620.0
HKD3_k127_7057320_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 580.0
HKD3_k127_7057320_2 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 451.0
HKD3_k127_7057320_3 - - - - 0.000000000000000000000000000000000000000000000000000000000006496 214.0
HKD3_k127_7057320_4 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000001473 196.0
HKD3_k127_7057320_5 LysM domain - - - 0.000000000000000000000000000000000000000000000000000383 187.0
HKD3_k127_7057320_6 - - - - 0.00000000000000000000000003239 111.0
HKD3_k127_7057320_7 translation initiation factor activity K06996 - - 0.0000000000000000000000001372 110.0
HKD3_k127_7101261_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 441.0
HKD3_k127_7101261_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 318.0
HKD3_k127_7101261_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000008083 169.0
HKD3_k127_7101261_3 PFAM AIG2 family protein K01457 - 3.5.1.54 0.00000000000000000000000000000000000395 149.0
HKD3_k127_7101261_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000002135 83.0
HKD3_k127_7101261_5 Helix-turn-helix domain - - - 0.000000000000000152 92.0
HKD3_k127_7249442_0 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 6.2e-217 680.0
HKD3_k127_7249442_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.557e-199 629.0
HKD3_k127_7249442_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000001932 101.0
HKD3_k127_7249442_12 - - - - 0.00000000304 61.0
HKD3_k127_7249442_13 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000003476 48.0
HKD3_k127_7249442_2 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 574.0
HKD3_k127_7249442_3 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 388.0
HKD3_k127_7249442_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 374.0
HKD3_k127_7249442_5 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 359.0
HKD3_k127_7249442_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000006056 252.0
HKD3_k127_7249442_7 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
HKD3_k127_7249442_8 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000001667 208.0
HKD3_k127_7249442_9 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000005894 164.0
HKD3_k127_7263511_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 8.178e-249 789.0
HKD3_k127_7263511_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 359.0
HKD3_k127_7263511_2 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002525 227.0
HKD3_k127_7263511_3 SMART Cold shock protein K03704 - - 0.000000000000000000000000002579 113.0
HKD3_k127_7264048_0 von Willebrand factor, type A K07114 - - 6.422e-291 913.0
HKD3_k127_7264048_1 Nucleoside recognition K06373 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001009 255.0
HKD3_k127_7264048_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000004192 197.0
HKD3_k127_7264048_3 Putative zinc-finger - - - 0.0000000000000000005689 100.0
HKD3_k127_7264048_4 SMART helix-turn-helix domain protein - - - 0.0000000000000004667 81.0
HKD3_k127_7264048_5 nucleoside recognition domain protein K06374 - - 0.0000000006407 67.0
HKD3_k127_7264048_6 regulation of single-species biofilm formation - - - 0.0005311 42.0
HKD3_k127_7269385_0 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 456.0
HKD3_k127_7269385_1 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 388.0
HKD3_k127_7279548_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 434.0
HKD3_k127_7279548_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
HKD3_k127_7279548_2 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000249 213.0
HKD3_k127_7279548_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000005292 134.0
HKD3_k127_7295434_0 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 514.0
HKD3_k127_7295434_1 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 417.0
HKD3_k127_7295434_2 Elongation factor Tu domain 2 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 338.0
HKD3_k127_7295434_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000005261 168.0
HKD3_k127_7295434_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000002911 145.0
HKD3_k127_7295434_5 Biotin-requiring enzyme - - - 0.000000000000001143 81.0
HKD3_k127_7302066_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 542.0
HKD3_k127_7302066_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 389.0
HKD3_k127_7302066_2 Protein of unknown function (DUF1460) - - - 0.00000005769 63.0
HKD3_k127_7307130_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 486.0
HKD3_k127_7307130_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000005635 163.0
HKD3_k127_7346910_0 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 485.0
HKD3_k127_7346910_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000003407 111.0
HKD3_k127_7374290_0 3-hydroxyacyl-CoA dehydrogenase K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 350.0
HKD3_k127_7374290_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 333.0
HKD3_k127_7374290_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000309 256.0
HKD3_k127_7381419_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003229 284.0
HKD3_k127_7381419_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
HKD3_k127_7381419_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000231 201.0
HKD3_k127_7382188_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 464.0
HKD3_k127_7382188_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
HKD3_k127_7382188_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000006816 179.0
HKD3_k127_7382188_3 holo-[acyl-carrier-protein] synthase activity K00997 - 2.7.8.7 0.00000000000000000000002754 103.0
HKD3_k127_7399468_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 515.0
HKD3_k127_7399468_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 462.0
HKD3_k127_7399468_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 336.0
HKD3_k127_7399468_3 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005825 157.0
HKD3_k127_7399468_4 hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000005165 131.0
HKD3_k127_7399468_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000949 122.0
HKD3_k127_7399468_6 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000006907 86.0
HKD3_k127_7399468_7 carbon dioxide binding K04653 - - 0.000000000000003598 78.0
HKD3_k127_7399890_0 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 450.0
HKD3_k127_7399890_1 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004709 258.0
HKD3_k127_7399890_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000004685 227.0
HKD3_k127_7399890_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000001515 78.0
HKD3_k127_7399890_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000001318 74.0
HKD3_k127_7407236_0 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001589 187.0
HKD3_k127_7407236_1 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000001051 151.0
HKD3_k127_7407236_2 diguanylate cyclase - - - 0.00000000000000000000002339 113.0
HKD3_k127_7407236_3 - - - - 0.0000000000000000007234 94.0
HKD3_k127_7407236_4 peptidase m48, ste24p - - - 0.0000000000007383 74.0
HKD3_k127_7415497_0 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 5.129e-276 863.0
HKD3_k127_7415497_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 4.487e-201 631.0
HKD3_k127_7415497_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 451.0
HKD3_k127_7415497_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 372.0
HKD3_k127_7415497_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 318.0
HKD3_k127_7415497_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000001738 223.0
HKD3_k127_7415497_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000238 207.0
HKD3_k127_7415497_7 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000005297 62.0
HKD3_k127_7415497_8 - - - - 0.000000499 52.0
HKD3_k127_7415497_9 Pfam:T6SS_VasB K11895 - - 0.00000372 50.0
HKD3_k127_7417470_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 354.0
HKD3_k127_7417470_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 308.0
HKD3_k127_7417470_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000306 179.0
HKD3_k127_7417470_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.0000000000004551 72.0
HKD3_k127_7417470_4 PFAM YHS domain - - - 0.0000005461 53.0
HKD3_k127_7439065_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.327e-240 748.0
HKD3_k127_7439065_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 582.0
HKD3_k127_7439065_10 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 346.0
HKD3_k127_7439065_11 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 353.0
HKD3_k127_7439065_12 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000524 239.0
HKD3_k127_7439065_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
HKD3_k127_7439065_14 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000772 211.0
HKD3_k127_7439065_15 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000001575 144.0
HKD3_k127_7439065_16 50S ribosomal protein L31 K02909 - - 0.000000000000000000000000000004779 120.0
HKD3_k127_7439065_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 512.0
HKD3_k127_7439065_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 514.0
HKD3_k127_7439065_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 501.0
HKD3_k127_7439065_5 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 401.0
HKD3_k127_7439065_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 403.0
HKD3_k127_7439065_7 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 371.0
HKD3_k127_7439065_8 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 364.0
HKD3_k127_7439065_9 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 373.0
HKD3_k127_7452523_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1232.0
HKD3_k127_7459801_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1596.0
HKD3_k127_7459801_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 384.0
HKD3_k127_7459801_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000005249 145.0
HKD3_k127_7459801_4 fimbrial assembly K02461 - - 0.00000000004269 76.0
HKD3_k127_7459801_5 Type II secretion system (T2SS), protein M subtype b - - - 0.0000007681 58.0
HKD3_k127_7468552_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 451.0
HKD3_k127_7468552_1 Formyl transferase K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004844 282.0
HKD3_k127_7468552_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000003612 175.0
HKD3_k127_7522401_0 AMP-binding enzyme C-terminal domain K01897,K16876 - 6.2.1.3,6.2.1.31 1.105e-241 756.0
HKD3_k127_7522401_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 530.0
HKD3_k127_7522401_2 Transcriptional regulator K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 434.0
HKD3_k127_7522401_3 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 383.0
HKD3_k127_7522401_4 Psort location Cytoplasmic, score K09144 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 301.0
HKD3_k127_7522401_5 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003813 280.0
HKD3_k127_7522401_6 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.00000000000000000000000000000000003019 149.0
HKD3_k127_7522401_8 redox protein, regulator of disulfide bond formation - - - 0.0000000001426 70.0
HKD3_k127_7527315_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703,K01176 - 2.4.1.21,3.2.1.1 1.655e-316 999.0
HKD3_k127_7527315_1 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 8.567e-247 770.0
HKD3_k127_7527315_10 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00002656 46.0
HKD3_k127_7527315_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 398.0
HKD3_k127_7527315_3 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 390.0
HKD3_k127_7527315_4 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 317.0
HKD3_k127_7527315_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000007474 241.0
HKD3_k127_7527315_6 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000002075 219.0
HKD3_k127_7527315_7 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000002358 216.0
HKD3_k127_7527315_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000001419 190.0
HKD3_k127_7527315_9 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000009398 181.0
HKD3_k127_753342_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 435.0
HKD3_k127_753342_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
HKD3_k127_7557634_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1065.0
HKD3_k127_7557634_1 aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 595.0
HKD3_k127_7557634_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000000000006163 164.0
HKD3_k127_756307_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 345.0
HKD3_k127_756307_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 332.0
HKD3_k127_7569483_0 Ammonium Transporter K03320 - - 3.407e-194 614.0
HKD3_k127_7569483_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
HKD3_k127_7569483_2 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000000006379 139.0
HKD3_k127_7569483_3 Serine aminopeptidase, S33 - - - 0.0000000000000000004368 90.0
HKD3_k127_7609096_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 512.0
HKD3_k127_7609096_1 COG0846 NAD-dependent protein deacetylases, SIR2 family K12410 - - 0.00000000000005592 73.0
HKD3_k127_7635658_0 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000005898 229.0
HKD3_k127_7635658_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000009266 205.0
HKD3_k127_7635658_2 Periplasmic binding protein K02016 - - 0.00000000000000000000000002683 114.0
HKD3_k127_7635658_3 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000001618 98.0
HKD3_k127_7645348_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 509.0
HKD3_k127_7645348_1 radical SAM domain protein K06937,K13309 - 4.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 371.0
HKD3_k127_7645348_2 NlpC/P60 family K19223 - - 0.0000000000000000000000000000000000000000000000000000000000001016 226.0
HKD3_k127_7645348_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000007544 129.0
HKD3_k127_7676986_0 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 517.0
HKD3_k127_7676986_1 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000001795 146.0
HKD3_k127_7676986_2 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000001129 73.0
HKD3_k127_768088_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1853.0
HKD3_k127_768088_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 582.0
HKD3_k127_7689009_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 319.0
HKD3_k127_7689009_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001659 268.0
HKD3_k127_7689009_2 PFAM Type II secretion system protein E K02454 - - 0.0002405 44.0
HKD3_k127_7705998_0 DSHCT - - - 4.611e-280 877.0
HKD3_k127_7705998_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 3.892e-272 845.0
HKD3_k127_7705998_10 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 320.0
HKD3_k127_7705998_11 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 295.0
HKD3_k127_7705998_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 287.0
HKD3_k127_7705998_13 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 286.0
HKD3_k127_7705998_14 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001341 298.0
HKD3_k127_7705998_15 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007397 261.0
HKD3_k127_7705998_16 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005915 253.0
HKD3_k127_7705998_17 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000001667 220.0
HKD3_k127_7705998_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000007973 193.0
HKD3_k127_7705998_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000404 197.0
HKD3_k127_7705998_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 8.268e-267 833.0
HKD3_k127_7705998_20 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000002046 188.0
HKD3_k127_7705998_21 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000003833 156.0
HKD3_k127_7705998_22 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000003251 149.0
HKD3_k127_7705998_23 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000001269 148.0
HKD3_k127_7705998_24 TonB C terminal K03832 - - 0.000000000000000000000000000000000000408 148.0
HKD3_k127_7705998_25 Amidohydrolase K07045 - - 0.0000000000000000000000000000000131 127.0
HKD3_k127_7705998_26 SMART Cold shock protein K03704 - - 0.00000000000000000000000000003435 117.0
HKD3_k127_7705998_27 response regulator K07689 - - 0.00000000000000000000000004266 124.0
HKD3_k127_7705998_29 PFAM response regulator receiver K07657 - - 0.000000000000000000004582 96.0
HKD3_k127_7705998_3 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 577.0
HKD3_k127_7705998_30 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000002544 96.0
HKD3_k127_7705998_31 - - - - 0.0000002462 52.0
HKD3_k127_7705998_32 McrBC 5-methylcytosine restriction system component - - - 0.000002343 51.0
HKD3_k127_7705998_33 dehydratase K17865 - 4.2.1.55 0.00002439 47.0
HKD3_k127_7705998_4 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 522.0
HKD3_k127_7705998_5 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 486.0
HKD3_k127_7705998_6 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 411.0
HKD3_k127_7705998_7 acetyl-CoA hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 402.0
HKD3_k127_7705998_8 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 369.0
HKD3_k127_7705998_9 SMART AAA ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 357.0
HKD3_k127_7750301_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 582.0
HKD3_k127_7750301_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 411.0
HKD3_k127_7750301_2 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
HKD3_k127_7750301_3 - - - - 0.0000000000000000000000000000000000000000000000008785 179.0
HKD3_k127_7833839_0 FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 570.0
HKD3_k127_7833839_1 antitermination protein NusG K05785 - - 0.000000000000000000000000000000000000000000000000000000000001193 216.0
HKD3_k127_7833839_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000813 203.0
HKD3_k127_7898940_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 7.796e-241 750.0
HKD3_k127_7898940_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 349.0
HKD3_k127_7898940_2 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
HKD3_k127_7898940_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000002432 209.0
HKD3_k127_7898940_4 FR47-like protein - - - 0.00000000000000000000000000000000000004474 148.0
HKD3_k127_7899510_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.562e-208 670.0
HKD3_k127_7899510_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 351.0
HKD3_k127_7917775_0 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 554.0
HKD3_k127_7917775_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 347.0
HKD3_k127_7917775_2 Putative regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000008904 207.0
HKD3_k127_7917775_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000005012 191.0
HKD3_k127_7917775_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000155 115.0
HKD3_k127_7927797_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 2.908e-246 766.0
HKD3_k127_7927797_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.437e-240 767.0
HKD3_k127_7927797_10 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001458 71.0
HKD3_k127_7927797_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 372.0
HKD3_k127_7927797_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 316.0
HKD3_k127_7927797_4 competence protein - - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
HKD3_k127_7927797_5 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000001824 188.0
HKD3_k127_7927797_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000001594 179.0
HKD3_k127_7927797_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000166 162.0
HKD3_k127_7927797_8 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000113 156.0
HKD3_k127_7927797_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000002004 93.0
HKD3_k127_7964086_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 471.0
HKD3_k127_7964086_1 AraC-type transcriptional regulator N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 438.0
HKD3_k127_7964086_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001599 291.0
HKD3_k127_7964086_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007507 268.0
HKD3_k127_7964086_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003227 223.0
HKD3_k127_7964086_5 Flavodoxin - - - 0.0000000000000000000000000000000002277 139.0
HKD3_k127_7975787_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 553.0
HKD3_k127_7975787_1 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 321.0
HKD3_k127_7975787_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005297 254.0
HKD3_k127_7990398_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 539.0
HKD3_k127_7990398_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 374.0
HKD3_k127_7990398_2 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 354.0
HKD3_k127_7990398_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 294.0
HKD3_k127_7990398_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
HKD3_k127_7990398_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000002021 231.0
HKD3_k127_7990398_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000005191 188.0
HKD3_k127_7990398_7 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000000000007792 149.0
HKD3_k127_7990398_8 Peptidase family M50 - - - 0.00000000000000000000000000000000000002012 148.0
HKD3_k127_7990398_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000008587 123.0
HKD3_k127_8060102_0 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 358.0
HKD3_k127_8060102_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 329.0
HKD3_k127_8060102_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000009904 206.0
HKD3_k127_8060102_3 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000001212 100.0
HKD3_k127_8060102_4 SEC-C motif - - - 0.0000002889 53.0
HKD3_k127_8119999_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 374.0
HKD3_k127_8119999_1 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
HKD3_k127_8119999_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000003792 238.0
HKD3_k127_8119999_3 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000001151 160.0
HKD3_k127_8119999_4 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000007517 146.0
HKD3_k127_8119999_5 lipolytic protein G-D-S-L family - - - 0.000000000000000000579 95.0
HKD3_k127_8119999_6 Late embryogenesis abundant protein - - - 0.0000000003219 67.0
HKD3_k127_8119999_7 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000005256 64.0
HKD3_k127_8161151_0 PFAM AMP-dependent synthetase and ligase K00666,K01897,K02182,K16876,K18661 - 6.2.1.3,6.2.1.31,6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 360.0
HKD3_k127_8161151_1 III protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 317.0
HKD3_k127_8161151_2 PFAM Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000001483 174.0
HKD3_k127_8161151_3 Response regulator receiver - - - 0.00000000000000000000000008651 113.0
HKD3_k127_8179737_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 566.0
HKD3_k127_8179737_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 548.0
HKD3_k127_8179737_2 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
HKD3_k127_8179737_3 Essential cell division protein K03589 - - 0.00000000000000000000000000000000000000000000000000000000004169 214.0
HKD3_k127_8179737_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000002431 201.0
HKD3_k127_8179737_5 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000003186 138.0
HKD3_k127_8179737_6 PspC domain - - - 0.0000000000000000000000000007243 113.0
HKD3_k127_8193646_0 AAA ATPase domain - - - 0.0 1226.0
HKD3_k127_8193646_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 418.0
HKD3_k127_8193646_2 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005501 273.0
HKD3_k127_8193646_3 - - - - 0.0000000000000000000000000000000000000000002835 164.0
HKD3_k127_8193646_4 - - - - 0.000000000000004712 79.0
HKD3_k127_8193646_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000008867 78.0
HKD3_k127_820078_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.072e-283 876.0
HKD3_k127_820078_1 ACT domain K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 316.0
HKD3_k127_820078_2 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00008055 49.0
HKD3_k127_8237996_0 type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 346.0
HKD3_k127_8237996_1 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 290.0
HKD3_k127_8237996_2 TPR repeat - - - 0.00000004654 64.0
HKD3_k127_8259703_0 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 306.0
HKD3_k127_8259703_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 304.0
HKD3_k127_8259703_2 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000006586 189.0
HKD3_k127_8259703_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000004073 113.0
HKD3_k127_8264674_0 S1, RNA binding domain K06959 - - 5.252e-318 989.0
HKD3_k127_8264674_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 395.0
HKD3_k127_8264674_2 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 314.0
HKD3_k127_8264674_3 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000001039 171.0
HKD3_k127_8264674_4 Helix-turn-helix domain - - - 0.0000006672 60.0
HKD3_k127_82699_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.548e-314 974.0
HKD3_k127_82699_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000002424 58.0
HKD3_k127_8282519_0 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 315.0
HKD3_k127_8282519_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000002481 97.0
HKD3_k127_8282519_2 Periplasmic binding protein K01999 - - 0.0000000008313 66.0
HKD3_k127_8300255_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 1.871e-268 844.0
HKD3_k127_8300255_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 496.0
HKD3_k127_831302_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 285.0
HKD3_k127_831302_1 Domain of unknown function (DUF4922) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 269.0
HKD3_k127_83292_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 398.0
HKD3_k127_83292_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002141 279.0
HKD3_k127_83292_2 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000276 86.0
HKD3_k127_8460132_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 294.0
HKD3_k127_8460132_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
HKD3_k127_8460132_2 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000002919 239.0
HKD3_k127_8460132_3 Iron-containing alcohol dehydrogenase K00001,K08325 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000004506 237.0
HKD3_k127_8460132_4 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000004883 166.0
HKD3_k127_8460132_5 - - - - 0.00000000000000000000000000001829 125.0
HKD3_k127_8460132_6 PFAM Amino acid-binding ACT - - - 0.000000000000000000000000007014 115.0
HKD3_k127_8460132_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000004928 85.0
HKD3_k127_8460132_8 Belongs to the thioredoxin family K03671 - - 0.00002129 53.0
HKD3_k127_8466018_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 567.0
HKD3_k127_8466018_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000002443 263.0
HKD3_k127_8466018_2 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000001336 154.0
HKD3_k127_8466018_3 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000001095 132.0
HKD3_k127_8466018_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000003846 103.0
HKD3_k127_8466018_5 Ribosomal L32p protein family K02911 - - 0.0000000000000000000001453 97.0
HKD3_k127_8466018_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000004006 63.0
HKD3_k127_8479752_0 type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 471.0
HKD3_k127_8479752_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K15327,K15329,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 345.0
HKD3_k127_8479752_2 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009873 274.0
HKD3_k127_8510809_0 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 388.0
HKD3_k127_8510809_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000007391 163.0
HKD3_k127_8510809_2 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000005251 133.0
HKD3_k127_8511109_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1354.0
HKD3_k127_8511109_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.964e-222 696.0
HKD3_k127_8511109_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.182e-211 668.0
HKD3_k127_8511109_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 497.0
HKD3_k127_8511109_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 375.0
HKD3_k127_8515806_0 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003734 277.0
HKD3_k127_8515806_1 Serine aminopeptidase, S33 K16050 - 3.7.1.17 0.000000000000000000000000000000000000000000000000001623 192.0
HKD3_k127_8521660_0 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 7.728e-287 897.0
HKD3_k127_8521660_1 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 483.0
HKD3_k127_8521660_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 461.0
HKD3_k127_8521660_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000001919 252.0
HKD3_k127_8521660_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
HKD3_k127_8521660_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000000000000002191 191.0
HKD3_k127_8521660_6 - - - - 0.0000000000000000000000000000000000000002981 157.0
HKD3_k127_8521660_7 AcrB/AcrD/AcrF family K03296,K18138 - - 0.000000000000000000000000000000187 125.0
HKD3_k127_8521660_8 - - - - 0.000000000000000000000005684 105.0
HKD3_k127_8521660_9 SMART Transport-associated and nodulation region - - - 0.000000007071 57.0
HKD3_k127_8523833_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 464.0
HKD3_k127_8523833_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 417.0
HKD3_k127_8523833_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 285.0
HKD3_k127_8523833_3 lactate metabolic process K00113,K21834 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000198 235.0
HKD3_k127_8523833_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000002131 207.0
HKD3_k127_8523833_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000001043 175.0
HKD3_k127_8523833_6 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000006144 147.0
HKD3_k127_8523833_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000006685 143.0
HKD3_k127_8523833_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000003507 132.0
HKD3_k127_8523833_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000001255 72.0
HKD3_k127_8544285_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.77e-321 988.0
HKD3_k127_8544285_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 1.96e-206 650.0
HKD3_k127_8544285_10 - - - - 0.0000000000000000000001834 99.0
HKD3_k127_8544285_12 Beta-propeller repeat - - - 0.00000000006947 75.0
HKD3_k127_8544285_13 CBD_II - - - 0.0000008884 62.0
HKD3_k127_8544285_14 TPR repeat - - - 0.00001659 55.0
HKD3_k127_8544285_15 curli production assembly transport component CsgG - - - 0.00002267 57.0
HKD3_k127_8544285_2 response regulator K02481,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 603.0
HKD3_k127_8544285_3 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 569.0
HKD3_k127_8544285_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 452.0
HKD3_k127_8544285_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 411.0
HKD3_k127_8544285_6 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 409.0
HKD3_k127_8544285_7 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001186 249.0
HKD3_k127_8544285_8 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000003189 248.0
HKD3_k127_8544285_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000209 213.0
HKD3_k127_8550322_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 339.0
HKD3_k127_8550322_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000002601 139.0
HKD3_k127_8550322_2 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000000000000000002391 122.0
HKD3_k127_8550322_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000000000003109 94.0
HKD3_k127_8570517_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.287e-242 753.0
HKD3_k127_8570517_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 476.0
HKD3_k127_8570517_10 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001905 162.0
HKD3_k127_8570517_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000005267 137.0
HKD3_k127_8570517_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000001198 140.0
HKD3_k127_8570517_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001307 109.0
HKD3_k127_8570517_14 peptidase U32 - - - 0.00000000000000000605 86.0
HKD3_k127_8570517_15 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000004111 79.0
HKD3_k127_8570517_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002116 70.0
HKD3_k127_8570517_17 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000003329 65.0
HKD3_k127_8570517_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 349.0
HKD3_k127_8570517_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 324.0
HKD3_k127_8570517_4 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002728 235.0
HKD3_k127_8570517_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004483 209.0
HKD3_k127_8570517_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000005985 206.0
HKD3_k127_8570517_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004023 204.0
HKD3_k127_8570517_8 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001227 174.0
HKD3_k127_8570517_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001527 170.0
HKD3_k127_8572057_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 1.374e-209 664.0
HKD3_k127_8572057_1 ABC transporter K06158 - - 2.503e-205 658.0
HKD3_k127_8572057_10 cheY-homologous receiver domain K07658 - - 0.00000000000000000000000001007 115.0
HKD3_k127_8572057_11 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000008817 98.0
HKD3_k127_8572057_12 phosphorelay signal transduction system - - - 0.00000000000000005728 85.0
HKD3_k127_8572057_2 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 399.0
HKD3_k127_8572057_3 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 406.0
HKD3_k127_8572057_4 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003108 273.0
HKD3_k127_8572057_5 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000005904 249.0
HKD3_k127_8572057_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HKD3_k127_8572057_7 Yip1 domain - - - 0.00000000000000000000000000000000000000000000000000000000002433 211.0
HKD3_k127_8572057_8 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000002013 213.0
HKD3_k127_8572057_9 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000008663 192.0
HKD3_k127_8583612_0 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 402.0
HKD3_k127_8583612_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 336.0
HKD3_k127_8583612_2 COG2202 FOG PAS PAC domain - - - 0.000000000000000000000000000000000000000000000000000000001007 230.0
HKD3_k127_8583612_3 Alanine-zipper, major outer membrane lipoprotein - - - 0.000000000000009597 78.0
HKD3_k127_8596438_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 437.0
HKD3_k127_8596438_1 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003077 248.0
HKD3_k127_8596438_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000005268 210.0
HKD3_k127_8596438_3 PP-loop family K14058 - - 0.00000000000000000000000000000000000000000000000002308 181.0
HKD3_k127_8596438_4 SMART Cold shock protein K03704 - - 0.00000000000000000000000000023 115.0
HKD3_k127_8596438_5 RNA recognition motif - - - 0.0000000000000000000004713 100.0
HKD3_k127_8596438_6 adenyl ribonucleotide binding - - - 0.00000000000000000001209 100.0
HKD3_k127_8596438_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000000000000000007656 95.0
HKD3_k127_8596438_9 domain protein K20276 - - 0.000000001783 71.0
HKD3_k127_8610137_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2414.0
HKD3_k127_8610137_1 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000004178 221.0
HKD3_k127_8610137_2 Rubrerythrin - - - 0.0000000000000000000000003598 110.0
HKD3_k127_8620177_0 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
HKD3_k127_8620177_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000001369 199.0
HKD3_k127_8620177_2 Lipoprotein - - - 0.0000000000000000000000000000000000000000000005641 170.0
HKD3_k127_8621498_0 GGDEF domain' - - - 0.000000000000000000000000000000000000000000000000000000000000000004372 238.0
HKD3_k127_8621498_1 LysM domain - - - 0.000000000000000000000000021 113.0
HKD3_k127_8621498_2 Winged helix-turn-helix DNA-binding - - - 0.000000000000002566 77.0
HKD3_k127_8641129_0 DegT/DnrJ/EryC1/StrS aminotransferase family K19715 - 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 500.0
HKD3_k127_8641129_1 PFAM Iron-containing alcohol dehydrogenase K00001,K19954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 369.0
HKD3_k127_8641129_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
HKD3_k127_8641129_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000008144 98.0
HKD3_k127_8686127_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 431.0
HKD3_k127_8686127_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 403.0
HKD3_k127_8686127_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000002715 58.0
HKD3_k127_8686658_0 Molybdate transporter of MFS superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
HKD3_k127_8686658_1 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
HKD3_k127_8686658_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 288.0
HKD3_k127_8686658_3 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000543 177.0
HKD3_k127_8686658_4 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000007755 168.0
HKD3_k127_8686658_5 Belongs to the HesB IscA family - - - 0.00000000001345 66.0
HKD3_k127_8694615_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 509.0
HKD3_k127_8694615_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 308.0
HKD3_k127_8694615_2 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 294.0
HKD3_k127_8694615_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003344 233.0
HKD3_k127_8694615_4 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000002656 208.0
HKD3_k127_8694615_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000006876 90.0
HKD3_k127_8694615_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000002415 86.0
HKD3_k127_8694615_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000005019 72.0
HKD3_k127_8696576_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1416.0
HKD3_k127_8696576_1 PFAM Acetyl-CoA hydrolase transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 451.0
HKD3_k127_8696576_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
HKD3_k127_8696576_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
HKD3_k127_8696576_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000001069 178.0
HKD3_k127_8704602_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 524.0
HKD3_k127_8704602_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
HKD3_k127_8704602_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 353.0
HKD3_k127_8704602_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000012 227.0
HKD3_k127_8704602_4 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000768 145.0
HKD3_k127_8704602_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000004688 100.0
HKD3_k127_8710593_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 549.0
HKD3_k127_8710593_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 435.0
HKD3_k127_8710593_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 316.0
HKD3_k127_8710593_3 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 305.0
HKD3_k127_8710593_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000013 142.0
HKD3_k127_8710593_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000004394 141.0
HKD3_k127_8710593_6 Outer membrane lipoprotein carrier protein LolA - - - 0.0000000000000000000000000000005353 130.0
HKD3_k127_8710593_7 Polyketide synthase dehydratase - - - 0.0000000000000000001398 100.0
HKD3_k127_8723552_0 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000001191 192.0
HKD3_k127_8723552_1 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000605 191.0
HKD3_k127_8723552_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000004224 173.0
HKD3_k127_8723552_3 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 0.0000000000005705 70.0
HKD3_k127_8747073_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 8.61e-218 681.0
HKD3_k127_8750801_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 430.0
HKD3_k127_8750801_1 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 398.0
HKD3_k127_8750801_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 394.0
HKD3_k127_8750801_3 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 355.0
HKD3_k127_8750801_4 Histidine kinase K00936,K07315 - 2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000003738 261.0
HKD3_k127_8750801_5 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000001799 208.0
HKD3_k127_8750801_7 PFAM Beta propeller domain K14475 - - 0.0000003519 58.0
HKD3_k127_8769059_0 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001682 285.0
HKD3_k127_8769059_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 252.0
HKD3_k127_8769059_2 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001625 230.0
HKD3_k127_8769059_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000001516 181.0
HKD3_k127_8769059_4 TonB-dependent receptor - - - 0.00000000000000002363 91.0
HKD3_k127_8769059_5 Fibronectin type III domain K03933 - - 0.00000003483 63.0
HKD3_k127_8788259_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 8.369e-204 643.0
HKD3_k127_8788259_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 363.0
HKD3_k127_8788259_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 359.0
HKD3_k127_8788259_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000001252 95.0
HKD3_k127_8809756_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 4.482e-263 816.0
HKD3_k127_8809756_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
HKD3_k127_8809756_2 Tetracycline repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HKD3_k127_8852392_0 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001488 273.0
HKD3_k127_8852392_1 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001598 248.0
HKD3_k127_8852392_2 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000001284 231.0
HKD3_k127_8852392_3 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000002118 199.0
HKD3_k127_8852392_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000001384 160.0
HKD3_k127_8852392_5 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000002406 136.0
HKD3_k127_8852392_6 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00000000000000000000000001119 115.0
HKD3_k127_8852392_7 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000008517 87.0
HKD3_k127_8870188_0 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002316 246.0
HKD3_k127_8870188_1 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000001482 205.0
HKD3_k127_8870188_2 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000007285 196.0
HKD3_k127_8886804_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 436.0
HKD3_k127_8886804_1 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 421.0
HKD3_k127_8886804_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
HKD3_k127_8886804_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000004004 192.0
HKD3_k127_8886804_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000001836 134.0
HKD3_k127_8886804_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000001293 75.0
HKD3_k127_8951975_0 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 467.0
HKD3_k127_8951975_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus - - - 0.000000000000000000000000000004446 122.0
HKD3_k127_8951975_2 Protein of unknown function (DUF1134) - - - 0.0000000000001466 70.0
HKD3_k127_8951975_3 Type II secretion system protein B K02451 - - 0.0000000000002637 81.0
HKD3_k127_8955165_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
HKD3_k127_8955165_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000001543 217.0
HKD3_k127_8955165_2 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000002561 197.0
HKD3_k127_8955165_3 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000002314 67.0
HKD3_k127_8965707_0 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 1.384e-230 727.0
HKD3_k127_8965707_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1.697e-213 674.0
HKD3_k127_8965707_10 Biotin-requiring enzyme - - - 0.0002405 44.0
HKD3_k127_8965707_2 HMGL-like - - - 5.522e-194 611.0
HKD3_k127_8965707_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 475.0
HKD3_k127_8965707_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 401.0
HKD3_k127_8965707_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 397.0
HKD3_k127_8965707_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 342.0
HKD3_k127_8965707_7 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001963 271.0
HKD3_k127_8965707_8 Preprotein translocase K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000005323 134.0
HKD3_k127_8965707_9 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000007427 81.0
HKD3_k127_8968616_0 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 296.0
HKD3_k127_8968616_1 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
HKD3_k127_8968616_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000002284 162.0
HKD3_k127_8968616_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000001224 146.0
HKD3_k127_8978356_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 419.0
HKD3_k127_8978356_1 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 399.0
HKD3_k127_8978356_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 359.0
HKD3_k127_8978356_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 314.0
HKD3_k127_8978356_4 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 289.0
HKD3_k127_9041388_0 Type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 426.0
HKD3_k127_9041388_1 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 331.0
HKD3_k127_9041388_2 PFAM TadE family protein - - - 0.00000000000000000000000000000004241 131.0
HKD3_k127_9083430_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 7.255e-196 618.0
HKD3_k127_9083430_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
HKD3_k127_9083430_2 Lipocalin-like domain - - - 0.000000000000000000000001318 108.0
HKD3_k127_9120779_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000545 284.0
HKD3_k127_9120779_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000003594 119.0
HKD3_k127_9121843_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 411.0
HKD3_k127_9121843_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001718 228.0
HKD3_k127_9130892_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 597.0
HKD3_k127_9130892_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 387.0
HKD3_k127_9130892_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 324.0
HKD3_k127_9130892_3 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
HKD3_k127_9135522_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 447.0
HKD3_k127_9135522_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 386.0
HKD3_k127_9135522_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000006286 200.0
HKD3_k127_9135522_3 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000000000000000000002082 159.0
HKD3_k127_9135522_4 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000006516 147.0
HKD3_k127_9135522_5 ACT domain - - - 0.0000000000000000000000000000001607 129.0
HKD3_k127_9135522_6 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000005678 128.0
HKD3_k127_9135522_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000002316 115.0
HKD3_k127_9135522_8 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000004201 83.0
HKD3_k127_9135522_9 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000007952 49.0
HKD3_k127_9168550_0 Sugar (and other) transporter - - - 1.156e-212 669.0
HKD3_k127_9168550_1 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 505.0
HKD3_k127_9168550_2 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 391.0
HKD3_k127_9168550_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000144 192.0
HKD3_k127_9380945_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 478.0
HKD3_k127_9380945_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 447.0
HKD3_k127_9380945_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 307.0
HKD3_k127_9444537_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 552.0
HKD3_k127_9444537_1 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000003674 113.0
HKD3_k127_964725_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001386 283.0
HKD3_k127_964725_1 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000000000000000000000003289 206.0
HKD3_k127_964725_2 PAS domain - - - 0.00000000000000000000000000000000000000000001256 183.0
HKD3_k127_964725_3 Universal stress protein family - - - 0.000000000000000000000000000000000008553 141.0
HKD3_k127_964725_4 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000002458 154.0
HKD3_k127_964725_5 regulation of response to stimulus - - - 0.000000000000001924 90.0
HKD3_k127_964725_6 - - - - 0.000000000006476 78.0
HKD3_k127_9654860_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1252.0
HKD3_k127_9654860_1 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 437.0
HKD3_k127_972829_0 Coenzyme A transferase K01026 - 2.8.3.1 0.0 1052.0
HKD3_k127_972829_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 490.0
HKD3_k127_972829_2 phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 406.0
HKD3_k127_972829_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001526 191.0
HKD3_k127_972829_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000003324 72.0