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Overview

ID MAG01839
Name HKD3_bin.19
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Armatimonadota
Class Hebobacteria
Order GCA-020354555
Family
Genus
Species
Assembly information
Completeness (%) 74.36
Contamination (%) 3.48
GC content (%) 62.0
N50 (bp) 3,510
Genome size (bp) 2,347,166

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2209

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1005299_0 Elongator protein 3, MiaB family, Radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000003573 187.0
HKD3_k127_1005299_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000009533 74.0
HKD3_k127_1018446_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000007909 149.0
HKD3_k127_1018446_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000001995 86.0
HKD3_k127_1018446_2 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000005014 58.0
HKD3_k127_1031067_0 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 545.0
HKD3_k127_1031067_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001999 256.0
HKD3_k127_1031067_2 - - - - 0.000000000000002003 84.0
HKD3_k127_1043022_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000001088 111.0
HKD3_k127_1043022_1 general secretion pathway protein K02456,K02650,K02679 - - 0.00000000000000002212 90.0
HKD3_k127_1043415_0 MgtE intracellular region K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
HKD3_k127_1043415_1 domain protein K03499,K10716 - - 0.000000000000000000000000000000000000000000002529 170.0
HKD3_k127_1043415_2 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00001512 48.0
HKD3_k127_1055961_0 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 375.0
HKD3_k127_1055961_1 - - - - 0.00000000000000000000000000000000000003047 162.0
HKD3_k127_1071446_0 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.000000000000000004696 85.0
HKD3_k127_1071446_1 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.0000000000001612 73.0
HKD3_k127_1071446_2 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.000000000006145 67.0
HKD3_k127_1071540_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 4.564e-243 766.0
HKD3_k127_1071540_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 344.0
HKD3_k127_1071540_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000118 161.0
HKD3_k127_1071540_3 - - - - 0.000000000000000000000000000000000000000001338 172.0
HKD3_k127_1071540_4 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000009065 156.0
HKD3_k127_1071540_5 PFAM ferredoxin-dependent glutamate synthase - - - 0.000000000000000000000000000000000000004796 147.0
HKD3_k127_1072944_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 572.0
HKD3_k127_1072944_1 transport system permease K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000133 286.0
HKD3_k127_1072944_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003299 280.0
HKD3_k127_1072944_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 279.0
HKD3_k127_1072944_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 273.0
HKD3_k127_1117944_0 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000004832 153.0
HKD3_k127_1117944_1 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000001201 148.0
HKD3_k127_1117944_2 Lrp/AsnC ligand binding domain - - - 0.0000000000007919 71.0
HKD3_k127_1117944_3 - - - - 0.00004089 51.0
HKD3_k127_1125486_0 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 559.0
HKD3_k127_1126646_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001809 259.0
HKD3_k127_1126646_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000007204 184.0
HKD3_k127_1126646_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000001003 99.0
HKD3_k127_1141617_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 357.0
HKD3_k127_1141617_1 Beta-galactosidase - - - 0.0000000001731 73.0
HKD3_k127_1141617_2 SMART Elongator protein 3 MiaB NifB K22226 - - 0.00000009464 64.0
HKD3_k127_1143572_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 484.0
HKD3_k127_1143572_1 Fibronectin type 3 domain - - - 0.0000000000000000001249 101.0
HKD3_k127_1157042_0 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 379.0
HKD3_k127_1157042_1 deacetylase - - - 0.00000000000002488 79.0
HKD3_k127_1164280_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000003061 189.0
HKD3_k127_1164280_1 Alpha mannosidase, middle domain - - - 0.00000000000000000000000000000000000000000000000005913 190.0
HKD3_k127_1164280_2 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000368 49.0
HKD3_k127_1170162_0 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000513 234.0
HKD3_k127_1170162_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000002955 229.0
HKD3_k127_1170162_2 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000832 224.0
HKD3_k127_1170162_3 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000006842 175.0
HKD3_k127_1170162_4 - - - - 0.0000007005 54.0
HKD3_k127_117472_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000002287 174.0
HKD3_k127_117472_1 polygalacturonase activity K13735 - - 0.0000000000000000000000000000000000000006404 160.0
HKD3_k127_1180594_0 Aconitase C-terminal domain K01681 - 4.2.1.3 6.016e-286 890.0
HKD3_k127_1180594_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 395.0
HKD3_k127_1180594_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000219 253.0
HKD3_k127_1221091_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.814e-217 692.0
HKD3_k127_1221091_1 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 312.0
HKD3_k127_1221091_2 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000003489 166.0
HKD3_k127_1221091_3 Histidine kinase K07654 - 2.7.13.3 0.00005975 54.0
HKD3_k127_1230305_0 TIGRFAM Translation elongation factor K02355 - - 6.436e-220 703.0
HKD3_k127_1230305_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003908 257.0
HKD3_k127_1230305_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
HKD3_k127_1230305_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000003349 184.0
HKD3_k127_1230305_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000001529 168.0
HKD3_k127_1230305_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000001099 151.0
HKD3_k127_1230305_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001347 128.0
HKD3_k127_1230305_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001685 104.0
HKD3_k127_1230305_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000001559 94.0
HKD3_k127_1230305_9 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000003579 66.0
HKD3_k127_1236105_0 Glycosyl-hydrolase family 116, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 365.0
HKD3_k127_1251965_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 313.0
HKD3_k127_1251965_1 xylulokinase activity K00848,K00851,K00854 - 2.7.1.12,2.7.1.17,2.7.1.5 0.00000000000007684 73.0
HKD3_k127_1253702_0 alcohol dehydrogenase K18012 - 1.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 349.0
HKD3_k127_1253702_1 HMGL-like K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 291.0
HKD3_k127_1253702_2 FCD - - - 0.0000000000000000000000000000545 125.0
HKD3_k127_1253702_3 Defective in exine formation - GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0007275,GO:0008150,GO:0009555,GO:0009653,GO:0009987,GO:0010208,GO:0010584,GO:0010927,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0030198,GO:0032501,GO:0032502,GO:0032989,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046872,GO:0048229,GO:0048646,GO:0048856,GO:0048869,GO:0071840,GO:0085029 - 0.00002531 57.0
HKD3_k127_1258440_0 carbohydrate binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 438.0
HKD3_k127_1263530_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004737 243.0
HKD3_k127_1263530_1 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000268 85.0
HKD3_k127_1263530_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000003721 74.0
HKD3_k127_1263530_3 - - - - 0.00001341 53.0
HKD3_k127_1263530_4 Phospholipid methyltransferase - - - 0.0001479 46.0
HKD3_k127_1306483_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 341.0
HKD3_k127_1306483_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000004593 227.0
HKD3_k127_1306483_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000006389 143.0
HKD3_k127_1306483_3 Organic solvent tolerance protein OstA K04744 - - 0.00000000000000000000004642 114.0
HKD3_k127_1306846_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
HKD3_k127_1306846_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000001358 202.0
HKD3_k127_1306846_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000002779 149.0
HKD3_k127_1306846_3 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000005043 128.0
HKD3_k127_1306846_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000001375 117.0
HKD3_k127_1306846_5 GlcNAc-PI de-N-acetylase - - - 0.000002064 51.0
HKD3_k127_1318044_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 386.0
HKD3_k127_1318044_1 ACT domain - - - 0.00000000000002253 74.0
HKD3_k127_1318547_0 Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 407.0
HKD3_k127_1318547_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 386.0
HKD3_k127_1318547_2 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 304.0
HKD3_k127_1319_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000002942 126.0
HKD3_k127_1319_1 Alpha mannosidase, middle domain - - - 0.000000000000000000000000000009114 125.0
HKD3_k127_1319_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000001616 72.0
HKD3_k127_1329362_0 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003302 275.0
HKD3_k127_1329362_1 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000002098 209.0
HKD3_k127_1329362_2 - - - - 0.0000000000000000000000000000000002968 139.0
HKD3_k127_1329362_3 PFAM glycoside hydrolase family 10 K01181 - 3.2.1.8 0.00000000000000698 75.0
HKD3_k127_1331134_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 388.0
HKD3_k127_1331134_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
HKD3_k127_1331134_2 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000007931 229.0
HKD3_k127_1331134_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000002579 191.0
HKD3_k127_1331134_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000001884 166.0
HKD3_k127_1331134_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000001815 156.0
HKD3_k127_1348110_0 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000001436 77.0
HKD3_k127_1348110_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000002385 64.0
HKD3_k127_1348110_2 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000001604 54.0
HKD3_k127_1348110_3 - - - - 0.0000428 51.0
HKD3_k127_1348886_0 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 551.0
HKD3_k127_1348886_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 457.0
HKD3_k127_1348886_2 Domain of unknown function K07053 - 3.1.3.97 0.0000000000000000000000001965 119.0
HKD3_k127_1368361_0 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 469.0
HKD3_k127_1368361_1 Transposase K07483 - - 0.000000000000000000000000000000000000000000000000004068 182.0
HKD3_k127_1371409_0 BNR repeat-like domain K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
HKD3_k127_1371409_1 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000002023 81.0
HKD3_k127_1372776_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 557.0
HKD3_k127_1372776_1 Transcriptional regulator - - - 0.000000000000000000000000000003359 124.0
HKD3_k127_1372776_3 Melibiase K07407 - 3.2.1.22 0.0000000007718 63.0
HKD3_k127_1372776_4 - - - - 0.0000001462 62.0
HKD3_k127_1376932_0 UPF0056 membrane protein K05595 - - 0.000000000000000000000000004251 118.0
HKD3_k127_1376932_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000003834 103.0
HKD3_k127_1378096_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 382.0
HKD3_k127_1378096_1 Major Facilitator Superfamily K02445,K07783 - - 0.0000000000000000000000000000000000000000000000000000000000000000001815 247.0
HKD3_k127_1378096_2 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000002578 123.0
HKD3_k127_138376_0 PFAM YibE F-like protein - - - 0.00000000000000000000000000000000000000000000000003805 186.0
HKD3_k127_138376_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000641 69.0
HKD3_k127_1387173_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000009775 239.0
HKD3_k127_1387173_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000001544 205.0
HKD3_k127_1408752_0 RNA polymerase sigma factor K03088 - - 0.00000000000000000003254 96.0
HKD3_k127_1408752_1 Melibiase - - - 0.0007783 46.0
HKD3_k127_1410453_0 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding - - - 0.0000000000000002661 83.0
HKD3_k127_1410453_1 Glycosyl hydrolase family 20, domain 2 - - - 0.0000002058 64.0
HKD3_k127_141730_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 563.0
HKD3_k127_141730_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 359.0
HKD3_k127_141730_2 Peptidase family M28 K01258,K01263 - 3.4.11.14,3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HKD3_k127_141730_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000001819 262.0
HKD3_k127_141730_4 Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000008043 196.0
HKD3_k127_141730_5 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000187 131.0
HKD3_k127_141730_6 DnaJ molecular chaperone homology domain - - - 0.00000000000001598 82.0
HKD3_k127_141730_7 - - - - 0.000000000007454 73.0
HKD3_k127_141730_8 Domain of unknown function (DUF1854) - - - 0.000000006681 57.0
HKD3_k127_1434284_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 475.0
HKD3_k127_1437383_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 329.0
HKD3_k127_1437383_1 DRTGG domain K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 266.0
HKD3_k127_1437383_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000001031 90.0
HKD3_k127_145554_0 lipopolysaccharide N-acetylmannosaminouronosyltransferase activity K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000001394 271.0
HKD3_k127_145554_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000004306 91.0
HKD3_k127_1465453_0 transmembrane transporter activity K03296 - - 0.0 1260.0
HKD3_k127_1465453_1 Pyridoxal-phosphate dependent enzyme K01883,K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000002961 261.0
HKD3_k127_1465453_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000291 61.0
HKD3_k127_1465453_3 Glycosyltransferase family 36 K18786 - 2.4.1.321 0.0000026 52.0
HKD3_k127_1465453_4 PFAM Bacterial Ig-like domain (group 2) - - - 0.0002302 54.0
HKD3_k127_1475133_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.937e-244 773.0
HKD3_k127_1475133_1 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 366.0
HKD3_k127_1475133_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003529 278.0
HKD3_k127_1475133_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000201 212.0
HKD3_k127_1475133_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000003204 135.0
HKD3_k127_1479598_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002084 272.0
HKD3_k127_1479598_1 arylsulfatase activity - - - 0.00000000000000000000000003409 115.0
HKD3_k127_1513922_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000001637 235.0
HKD3_k127_1513922_1 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000618 51.0
HKD3_k127_151534_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 395.0
HKD3_k127_151534_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000711 156.0
HKD3_k127_151534_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000001936 145.0
HKD3_k127_151534_3 peptide deformylase activity K00604,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.1.2.9,3.5.1.88 0.0000000000000000000000000000000002777 136.0
HKD3_k127_151534_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000002424 91.0
HKD3_k127_151534_5 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00004127 47.0
HKD3_k127_1521768_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 395.0
HKD3_k127_1521768_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000001941 244.0
HKD3_k127_1521768_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000004143 162.0
HKD3_k127_1548085_0 Alpha mannosidase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 551.0
HKD3_k127_1579402_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 556.0
HKD3_k127_1579402_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 415.0
HKD3_k127_1579402_2 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000001461 170.0
HKD3_k127_1579402_3 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000002665 152.0
HKD3_k127_1588694_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002971 283.0
HKD3_k127_1588694_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
HKD3_k127_1588694_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000001173 111.0
HKD3_k127_1593956_1 Negative regulator of sigma E activity K03598 - - 0.0000002676 62.0
HKD3_k127_1595612_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 319.0
HKD3_k127_1595612_1 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000001314 229.0
HKD3_k127_1605712_0 Pectate lyase K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 391.0
HKD3_k127_1605712_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000003191 194.0
HKD3_k127_1605712_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000005087 140.0
HKD3_k127_1605712_3 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000001663 108.0
HKD3_k127_1605712_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0005763 44.0
HKD3_k127_1612404_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000001069 178.0
HKD3_k127_1612404_1 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.000000000000000000000000007535 122.0
HKD3_k127_1612404_2 Heparinase II/III-like protein - - - 0.0000000000008174 81.0
HKD3_k127_1612404_3 Glucose 1-dehydrogenase - - - 0.00006274 54.0
HKD3_k127_1614479_0 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 332.0
HKD3_k127_1614479_1 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 291.0
HKD3_k127_1614479_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000002729 212.0
HKD3_k127_1614479_3 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000008807 180.0
HKD3_k127_1614479_4 ACT domain protein - - - 0.00000000000000000000000000112 119.0
HKD3_k127_1614479_5 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000001983 79.0
HKD3_k127_1615844_0 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000001793 220.0
HKD3_k127_1615844_2 heme-binding sites - - - 0.00006543 56.0
HKD3_k127_1623170_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 422.0
HKD3_k127_1668984_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 325.0
HKD3_k127_1671334_0 Carboxypeptidase regulatory-like domain - - - 0.0002878 53.0
HKD3_k127_1709343_0 - - - - 0.00000008575 64.0
HKD3_k127_1714019_0 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000009147 212.0
HKD3_k127_1714019_1 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000002085 216.0
HKD3_k127_1748073_0 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 364.0
HKD3_k127_1748073_1 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000005216 239.0
HKD3_k127_1748073_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000003375 218.0
HKD3_k127_1748073_3 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000001085 173.0
HKD3_k127_1748073_4 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000009405 108.0
HKD3_k127_1748073_5 O-Antigen ligase - - - 0.0000000000000405 85.0
HKD3_k127_1755789_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 512.0
HKD3_k127_1755789_1 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000001122 210.0
HKD3_k127_1755789_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000007038 121.0
HKD3_k127_1755789_3 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000001332 57.0
HKD3_k127_1756902_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 1.262e-212 695.0
HKD3_k127_1761782_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
HKD3_k127_1761782_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008813 253.0
HKD3_k127_1761782_2 PQQ enzyme repeat - - - 0.000000000000000000000000000004592 138.0
HKD3_k127_1761782_3 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.000000004895 70.0
HKD3_k127_1772967_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000002195 109.0
HKD3_k127_1772967_1 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000001003 106.0
HKD3_k127_1775966_0 SMART AAA ATPase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 288.0
HKD3_k127_1775966_1 Belongs to the 'phage' integrase family - - - 0.000000000000000126 92.0
HKD3_k127_1788808_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001352 254.0
HKD3_k127_1788808_1 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000001005 113.0
HKD3_k127_1794481_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 331.0
HKD3_k127_1794481_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001041 258.0
HKD3_k127_1794481_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000005648 77.0
HKD3_k127_1819668_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 499.0
HKD3_k127_1821972_0 CHAP domain - - - 0.00000000000000000000000000000000002769 154.0
HKD3_k127_1821972_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000002902 152.0
HKD3_k127_1823128_0 Elongation factor Tu domain 2 K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 491.0
HKD3_k127_1823128_1 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 322.0
HKD3_k127_1823128_2 peptidyl-tyrosine sulfation - - - 0.00001778 53.0
HKD3_k127_1823560_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 304.0
HKD3_k127_1823560_1 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004133 279.0
HKD3_k127_1823560_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 280.0
HKD3_k127_1823560_3 DNA methylase K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000001098 206.0
HKD3_k127_1823560_4 toxin-antitoxin pair type II binding - - - 0.000000003136 63.0
HKD3_k127_1827052_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 362.0
HKD3_k127_1827052_1 Domain of unknown function (DUF5060) - - - 0.000000000000000000000000000000000000000000000000000000009574 200.0
HKD3_k127_1827052_2 - - - - 0.000000000000000000000000000000000000000000000005988 190.0
HKD3_k127_1827052_3 cobalamin binding - - - 0.00000000000000000000000000000000000000000004208 174.0
HKD3_k127_1827052_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000005408 167.0
HKD3_k127_1853031_0 PFAM Heparinase II III family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 308.0
HKD3_k127_1853031_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000001589 184.0
HKD3_k127_1853031_2 Belongs to the UPF0178 family - - - 0.0000000000000000000000000000002033 127.0
HKD3_k127_1853031_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000006479 132.0
HKD3_k127_1866905_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 459.0
HKD3_k127_1866905_1 Hypothetical methyltransferase - - - 0.000000006146 66.0
HKD3_k127_1871712_0 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005197 254.0
HKD3_k127_1871712_1 chitinase K01183 - 3.2.1.14 0.000000000000000000000004219 120.0
HKD3_k127_1884910_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 612.0
HKD3_k127_1884910_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000172 243.0
HKD3_k127_188791_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000494 166.0
HKD3_k127_188791_1 Domain of unknown function (DUF362) - - - 0.000000000001339 76.0
HKD3_k127_1903645_0 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000001805 98.0
HKD3_k127_1903645_1 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000201 70.0
HKD3_k127_1903645_2 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000001685 61.0
HKD3_k127_1903645_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000007867 57.0
HKD3_k127_191976_0 Type II IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 546.0
HKD3_k127_191976_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 411.0
HKD3_k127_1928086_0 GGDEF domain K02405,K03090,K03409 - - 0.0000000000000000000000000000000000000000000000000000000001939 220.0
HKD3_k127_1928086_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000001634 104.0
HKD3_k127_1928086_2 Domain of unknown function (DUF4139) - - - 0.00000000000000000001258 96.0
HKD3_k127_194163_0 PFAM UDP-glucose GDP-mannose dehydrogenase family, NAD binding domain K02472,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 482.0
HKD3_k127_194163_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 290.0
HKD3_k127_194163_2 Universal stress protein family - - - 0.000000000000000000000006721 105.0
HKD3_k127_195410_0 Hypothetical glycosyl hydrolase 6 - - - 0.000000000000000000000000000000000000000000000000000006808 199.0
HKD3_k127_195410_1 - - - - 0.000000000000000000000000000000000000000000000000007253 186.0
HKD3_k127_195410_2 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000001098 124.0
HKD3_k127_195410_3 bacitracin transport permease K19302 - 3.6.1.27 0.0000000000000004536 85.0
HKD3_k127_195410_4 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000002747 70.0
HKD3_k127_195410_5 PFAM metallophosphoesterase - - - 0.0005523 52.0
HKD3_k127_1961680_1 Subtilase family - - - 0.00000000000007944 84.0
HKD3_k127_200113_0 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 464.0
HKD3_k127_200113_1 PFAM penicillin-binding protein transpeptidase, Penicillin-binding protein dimerization domain-containing protein, PASTA domain containing protein K08384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 390.0
HKD3_k127_200113_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 373.0
HKD3_k127_200113_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 344.0
HKD3_k127_200113_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HKD3_k127_200113_5 Peptidoglycan polymerase that is essential for cell division K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 - 0.0000000000000000000000000004232 123.0
HKD3_k127_200113_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000006727 75.0
HKD3_k127_2009628_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
HKD3_k127_2009628_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000002664 218.0
HKD3_k127_2021127_0 general secretion pathway protein K02456,K02679 - - 0.000000002331 66.0
HKD3_k127_2021127_1 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.00006739 53.0
HKD3_k127_2031231_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000004607 164.0
HKD3_k127_2031231_1 chaperone-mediated protein folding - - - 0.00000000000000005034 84.0
HKD3_k127_2057131_1 Belongs to the peptidase S16 family - - - 0.000000002797 70.0
HKD3_k127_2058459_0 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 443.0
HKD3_k127_2058459_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 418.0
HKD3_k127_2058459_2 COG1413 FOG HEAT repeat K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 351.0
HKD3_k127_2058459_3 Pfam L-fucose isomerase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 346.0
HKD3_k127_2058459_4 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 299.0
HKD3_k127_2058459_5 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000003383 233.0
HKD3_k127_2058459_6 DoxX K16937 - 1.8.5.2 0.0000000001508 68.0
HKD3_k127_2063439_0 phosphoglucosamine mutase activity K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 385.0
HKD3_k127_2085435_0 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002439 280.0
HKD3_k127_2085435_1 Glycogen debranching enzyme K18206 - 3.2.1.187 0.00000000000000000000000000000000000000000000000000000000001647 230.0
HKD3_k127_2085435_2 Gamma-glutamyltranspeptidase - - - 0.000000000000000000000000000000000000000000000000000000001872 219.0
HKD3_k127_2085435_3 - - - - 0.00000000003347 72.0
HKD3_k127_2085435_4 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.00005488 56.0
HKD3_k127_2089311_0 Peptidase S8 and S53 subtilisin kexin sedolisin K01342,K14645 - 3.4.21.62 0.000000000000000000000000000000000000000246 169.0
HKD3_k127_2089311_1 Acetyltransferase (GNAT) domain - - - 0.00004737 53.0
HKD3_k127_2119300_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.046e-275 856.0
HKD3_k127_2119300_1 WD40-like Beta Propeller Repeat K03641,K08676 - - 0.000000000000000001726 100.0
HKD3_k127_2171048_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 452.0
HKD3_k127_2171048_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000001193 232.0
HKD3_k127_2183984_0 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000007664 206.0
HKD3_k127_2183984_1 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000001153 181.0
HKD3_k127_2183984_2 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000002279 158.0
HKD3_k127_2183984_3 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000002315 135.0
HKD3_k127_2183984_4 DRTGG domain - - - 0.0000000000000000000002282 100.0
HKD3_k127_2183984_5 cheY-homologous receiver domain K07658 - - 0.0000000000000000001341 99.0
HKD3_k127_2183984_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000222 62.0
HKD3_k127_2183984_7 helix_turn_helix, Lux Regulon - - - 0.000000005043 67.0
HKD3_k127_2184731_0 COG COG1879 ABC-type sugar transport system, periplasmic component K10439 - - 0.000004944 54.0
HKD3_k127_21989_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 481.0
HKD3_k127_21989_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000268 188.0
HKD3_k127_2222803_0 cell division K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001277 258.0
HKD3_k127_2222803_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000357 229.0
HKD3_k127_2222803_2 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000003885 149.0
HKD3_k127_2222803_3 Cytochrome c - - - 0.000000000000000000001985 104.0
HKD3_k127_2222803_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0009906 45.0
HKD3_k127_2225175_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 602.0
HKD3_k127_2225175_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000000000000001414 115.0
HKD3_k127_2249768_0 Cysteine-rich secretory protein family - - - 0.00002288 53.0
HKD3_k127_2254546_0 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004862 250.0
HKD3_k127_2276405_0 PFAM Peptidase family M23 - - - 0.000000000000000000001056 102.0
HKD3_k127_2281612_0 COG0577 ABC-type antimicrobial peptide transport system, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 345.0
HKD3_k127_2281612_1 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 294.0
HKD3_k127_2281612_2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003,K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000779 256.0
HKD3_k127_2293737_0 alginic acid biosynthetic process - - - 1.866e-197 635.0
HKD3_k127_2301025_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 4.271e-204 644.0
HKD3_k127_2301025_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000005578 129.0
HKD3_k127_2303318_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 363.0
HKD3_k127_2303318_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006715 223.0
HKD3_k127_2303318_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000003507 132.0
HKD3_k127_2303318_3 glycosyl transferase group 1 K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000002427 110.0
HKD3_k127_2303645_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000001064 147.0
HKD3_k127_2303645_1 sh3 domain protein - - - 0.00000004966 67.0
HKD3_k127_2303645_2 Putative zinc-finger - - - 0.00003558 56.0
HKD3_k127_2313070_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 596.0
HKD3_k127_2313070_3 Belongs to the peptidase S8 family - - - 0.0000000000002496 78.0
HKD3_k127_2313070_4 Glycoside hydrolase family 44 K01179 - 3.2.1.4 0.0002017 51.0
HKD3_k127_2327485_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 421.0
HKD3_k127_2327485_1 general secretion pathway protein K02456 - - 0.0000000000000000000001637 105.0
HKD3_k127_2332858_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000007822 252.0
HKD3_k127_2332858_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000003876 222.0
HKD3_k127_2332858_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000009213 123.0
HKD3_k127_2338464_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 574.0
HKD3_k127_2338464_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000003074 157.0
HKD3_k127_2338464_2 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000007941 139.0
HKD3_k127_2338464_3 negative regulation of DNA recombination - - - 0.00000000005344 72.0
HKD3_k127_2343121_0 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000007665 151.0
HKD3_k127_2343121_1 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000006607 154.0
HKD3_k127_2353066_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 339.0
HKD3_k127_2353066_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 323.0
HKD3_k127_2353066_2 drug transmembrane transporter activity K03327,K18908 GO:0000302,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0006857,GO:0006862,GO:0006950,GO:0006979,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015215,GO:0015230,GO:0015238,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0033554,GO:0034220,GO:0034599,GO:0034614,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0042891,GO:0042895,GO:0042938,GO:0044464,GO:0044610,GO:0046677,GO:0050896,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1901700,GO:1901701,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 293.0
HKD3_k127_2353066_3 Papain-like cysteine protease AvrRpt2 - - - 0.00000000000000000000005033 106.0
HKD3_k127_2353066_4 Tetratricopeptide repeat protein - - - 0.0000001566 62.0
HKD3_k127_2357859_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
HKD3_k127_2357859_1 triose-phosphate isomerase activity K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
HKD3_k127_2357859_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HKD3_k127_2357859_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000008664 162.0
HKD3_k127_2357859_4 Domain of unknown function (DUF366) K09139 - - 0.00000000000000000000000000000002969 136.0
HKD3_k127_2360047_0 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000003206 248.0
HKD3_k127_2360047_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
HKD3_k127_2362841_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 569.0
HKD3_k127_2362841_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 384.0
HKD3_k127_2362841_2 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 376.0
HKD3_k127_2362841_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 293.0
HKD3_k127_2362841_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
HKD3_k127_2362841_5 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000004848 231.0
HKD3_k127_2362841_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000001594 178.0
HKD3_k127_2412487_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 370.0
HKD3_k127_2412487_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000008303 185.0
HKD3_k127_2412487_2 Succinylglutamate desuccinylase aspartoacylase - - - 0.000003719 61.0
HKD3_k127_2419678_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008517 284.0
HKD3_k127_2419678_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000002271 186.0
HKD3_k127_2427153_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 447.0
HKD3_k127_2427153_1 diguanylate cyclase - - - 0.00005141 54.0
HKD3_k127_2438494_0 L-arabinose isomerase activity K01804 - 5.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 322.0
HKD3_k127_2438494_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001388 257.0
HKD3_k127_2438494_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000001186 121.0
HKD3_k127_2464691_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 456.0
HKD3_k127_2464691_1 OsmC-like protein K07397 - - 0.0000000000001194 75.0
HKD3_k127_2479490_0 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000003882 200.0
HKD3_k127_2479490_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000007315 189.0
HKD3_k127_2479490_2 Domain of unknown function (DUF5060) - - - 0.0000000000000000000000000000000000002664 142.0
HKD3_k127_2479490_3 Domain of unknown function (DUF5060) - - - 0.000000000002186 66.0
HKD3_k127_2487631_0 Involved in the tonB-independent uptake of proteins K01730,K03641 - 4.2.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 349.0
HKD3_k127_2528827_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 462.0
HKD3_k127_2528827_1 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 345.0
HKD3_k127_2542619_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 549.0
HKD3_k127_2542619_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000255 122.0
HKD3_k127_2558388_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 505.0
HKD3_k127_256421_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001255 250.0
HKD3_k127_256421_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000844 240.0
HKD3_k127_256421_2 acyl carrier - - - 0.0000000000002003 73.0
HKD3_k127_256421_3 ATP hydrolysis coupled proton transport - - - 0.000000001407 67.0
HKD3_k127_2565835_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000005403 101.0
HKD3_k127_2565835_1 beta-fructofuranosidase activity - - - 0.00000000000003107 74.0
HKD3_k127_2568916_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005528 252.0
HKD3_k127_257688_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 512.0
HKD3_k127_257688_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001579 262.0
HKD3_k127_257688_2 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000001846 124.0
HKD3_k127_2594170_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
HKD3_k127_2594170_1 Peptidase, M48 family K07387 - - 0.000000000005559 68.0
HKD3_k127_2596999_0 PFAM Pyruvate carboxyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 392.0
HKD3_k127_2596999_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000009298 144.0
HKD3_k127_2596999_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000003675 60.0
HKD3_k127_2629667_0 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000003834 149.0
HKD3_k127_2629667_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000006698 148.0
HKD3_k127_2629667_2 Stage II sporulation protein K06381 - - 0.000000286 59.0
HKD3_k127_2639328_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 419.0
HKD3_k127_2639328_1 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 314.0
HKD3_k127_2639328_2 PFAM glycoside hydrolase, family 4 K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 291.0
HKD3_k127_2639328_3 phosphorelay signal transduction system - - - 0.000000000000000004608 92.0
HKD3_k127_2644886_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 2.047e-283 885.0
HKD3_k127_2644886_1 - - - - 0.000000000002993 67.0
HKD3_k127_2644886_2 - - - - 0.00000000002473 72.0
HKD3_k127_2659052_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 314.0
HKD3_k127_2659052_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000008047 156.0
HKD3_k127_2659052_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000003002 98.0
HKD3_k127_2659052_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000001174 57.0
HKD3_k127_2665664_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.116e-217 694.0
HKD3_k127_2665664_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000005494 227.0
HKD3_k127_2670803_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000147 271.0
HKD3_k127_2670803_1 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
HKD3_k127_267736_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000002596 237.0
HKD3_k127_267736_1 HlyD family secretion protein - - - 0.00000000000000001463 96.0
HKD3_k127_267736_2 PFAM outer membrane efflux protein - - - 0.00005627 51.0
HKD3_k127_2680906_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.382e-237 748.0
HKD3_k127_2680906_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 552.0
HKD3_k127_2680906_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000008444 265.0
HKD3_k127_2680906_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00007088 48.0
HKD3_k127_2694666_0 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 419.0
HKD3_k127_2694666_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000001811 144.0
HKD3_k127_2702901_0 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002618 245.0
HKD3_k127_2702901_1 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000001066 217.0
HKD3_k127_2702901_2 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000009499 188.0
HKD3_k127_2710571_0 bile acid beta-glucosidase K17108 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000004487 195.0
HKD3_k127_2710571_1 Tat pathway signal sequence domain protein - - - 0.00000000000000000000000000001042 132.0
HKD3_k127_2710571_2 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000005201 116.0
HKD3_k127_2711527_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000009381 155.0
HKD3_k127_2711527_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000003615 70.0
HKD3_k127_2711527_2 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000003976 53.0
HKD3_k127_2717358_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 382.0
HKD3_k127_2725331_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 343.0
HKD3_k127_2725331_1 - - - - 0.000000000000000000000000000004116 134.0
HKD3_k127_2754423_0 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000006056 186.0
HKD3_k127_2754423_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000008933 122.0
HKD3_k127_277752_0 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 400.0
HKD3_k127_277752_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 298.0
HKD3_k127_277752_2 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 282.0
HKD3_k127_277752_3 Tetratricopeptide repeat - - - 0.0000005591 62.0
HKD3_k127_2824686_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 339.0
HKD3_k127_2824686_1 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0001534 49.0
HKD3_k127_2838974_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 361.0
HKD3_k127_2838974_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 277.0
HKD3_k127_2848191_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 430.0
HKD3_k127_2848191_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 417.0
HKD3_k127_2848191_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 421.0
HKD3_k127_2848191_3 ABC-type multidrug transport system ATPase K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002321 250.0
HKD3_k127_2848191_4 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000003828 173.0
HKD3_k127_2848191_5 - - - - 0.000000000000000000000002449 115.0
HKD3_k127_2848191_6 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.000002831 59.0
HKD3_k127_2850055_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 385.0
HKD3_k127_2850055_1 Laminin G domain - - - 0.00000000003726 76.0
HKD3_k127_2854067_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.357e-300 938.0
HKD3_k127_2854067_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006896 254.0
HKD3_k127_2860005_0 PFAM peptidase domain protein - - - 0.0001654 53.0
HKD3_k127_2860988_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 420.0
HKD3_k127_2860988_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 342.0
HKD3_k127_2860988_2 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000002595 125.0
HKD3_k127_289174_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 487.0
HKD3_k127_289174_1 Scramblase - - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
HKD3_k127_289174_2 - - - - 0.000000000000000000000000000000000000000000001461 175.0
HKD3_k127_289174_3 - - - - 0.000000000000000000000000000000000000000006175 162.0
HKD3_k127_2899023_0 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 590.0
HKD3_k127_2899023_1 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
HKD3_k127_2899023_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
HKD3_k127_2899023_3 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000002119 213.0
HKD3_k127_291559_0 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001387 260.0
HKD3_k127_291559_1 - - - - 0.000000000000000000000000000001072 123.0
HKD3_k127_2920594_0 proteolysis K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
HKD3_k127_2920594_1 endo-1,4-beta-xylanase activity K21606 - 3.2.1.202 0.0000000000000000000000000000000000000000000000000000000003205 232.0
HKD3_k127_2920594_2 self proteolysis K01181,K02027,K17315,K17318 - 3.2.1.8 0.000000000000000000000000000000000000000001528 181.0
HKD3_k127_2920594_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000002628 90.0
HKD3_k127_2934175_1 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000006054 177.0
HKD3_k127_2939340_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
HKD3_k127_2939340_1 - - - - 0.00000000000000000000000000000000000000000000000007544 189.0
HKD3_k127_2939340_2 - - - - 0.00000000000000000000000000000000000000001015 162.0
HKD3_k127_2954740_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 478.0
HKD3_k127_2954740_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000424 156.0
HKD3_k127_2954740_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000001359 123.0
HKD3_k127_2954740_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000033 82.0
HKD3_k127_2954740_4 Metal-sensitive transcriptional repressor K21600 - - 0.00000000001082 68.0
HKD3_k127_2961967_0 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 486.0
HKD3_k127_2961967_1 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.000000000000000000000000000000000000000000000000000000000000003747 223.0
HKD3_k127_2961967_2 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000726 138.0
HKD3_k127_2961967_3 COG0457 FOG TPR repeat - - - 0.00000000000000003424 92.0
HKD3_k127_2967925_0 ABC transporter, ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
HKD3_k127_2967925_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000818 81.0
HKD3_k127_2967925_2 MlaD protein K02067 - - 0.00000000009879 72.0
HKD3_k127_2971041_0 beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 445.0
HKD3_k127_2971041_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HKD3_k127_2971041_2 diguanylate cyclase - - - 0.00000000000005157 83.0
HKD3_k127_2971415_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 362.0
HKD3_k127_2971415_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 337.0
HKD3_k127_2971415_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000004673 230.0
HKD3_k127_2971415_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000377 147.0
HKD3_k127_2971415_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000177 128.0
HKD3_k127_2971415_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000007572 118.0
HKD3_k127_2971415_6 FR47-like protein - - - 0.0000000000000000007851 94.0
HKD3_k127_2971997_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000000000000000002057 104.0
HKD3_k127_2971997_1 Beta-lactamase enzyme family - - - 0.0000001922 56.0
HKD3_k127_3002319_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 417.0
HKD3_k127_3002319_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000563 112.0
HKD3_k127_3002319_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000004283 88.0
HKD3_k127_3004390_0 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
HKD3_k127_3004390_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000001275 128.0
HKD3_k127_3023033_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 417.0
HKD3_k127_3023033_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000005078 129.0
HKD3_k127_3023033_2 Polysaccharide lyase family 4, domain III - - - 0.0000000000000000000000000002204 121.0
HKD3_k127_3027403_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000001024 194.0
HKD3_k127_3027403_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000009489 161.0
HKD3_k127_3027403_2 PFAM glycosyl transferase family 39 - - - 0.00000000008083 67.0
HKD3_k127_3029818_0 Belongs to the pyrroline-5-carboxylate reductase family K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009651,GO:0016491,GO:0016645,GO:0016646,GO:0030312,GO:0044424,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000003088 235.0
HKD3_k127_3029818_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000005061 216.0
HKD3_k127_3029818_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000001324 109.0
HKD3_k127_3029818_3 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000003168 92.0
HKD3_k127_3029818_4 DUF167 K09131 - - 0.00000000000009435 75.0
HKD3_k127_3052593_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
HKD3_k127_3052593_1 Cupin - - - 0.0000000000000000000005179 100.0
HKD3_k127_3052593_2 - - - - 0.0008243 50.0
HKD3_k127_3055508_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 339.0
HKD3_k127_3055508_1 2-epimerase K01787,K16213 - 5.1.3.11,5.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
HKD3_k127_3055508_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000001211 188.0
HKD3_k127_3055508_3 Right handed beta helix region - - - 0.000000000000000000000000002341 116.0
HKD3_k127_3055508_4 O-methyltransferase - - - 0.000008563 57.0
HKD3_k127_3073292_0 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
HKD3_k127_3087612_0 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 511.0
HKD3_k127_3087612_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 332.0
HKD3_k127_3087612_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 261.0
HKD3_k127_3087612_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000003045 192.0
HKD3_k127_3087612_4 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000338 167.0
HKD3_k127_3103441_0 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 481.0
HKD3_k127_3103441_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 323.0
HKD3_k127_3103441_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 305.0
HKD3_k127_3103441_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000001641 157.0
HKD3_k127_3103441_4 oxidoreductase activity - - - 0.0000000000000000000000005112 106.0
HKD3_k127_3104154_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 407.0
HKD3_k127_3104154_1 Peptidase M23 K21471 - - 0.0000000000000000000000000000000000000000000009969 183.0
HKD3_k127_3104154_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000002272 166.0
HKD3_k127_3104154_3 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000009703 103.0
HKD3_k127_3104154_5 Prokaryotic N-terminal methylation motif K02456 - - 0.0000001206 59.0
HKD3_k127_3104154_6 Ami_2 K01447 - 3.5.1.28 0.0001081 53.0
HKD3_k127_3112540_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 2.788e-210 662.0
HKD3_k127_3112540_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000004274 253.0
HKD3_k127_3112540_2 ANTAR K22010 - - 0.00000000000000000000000000000000000000001348 161.0
HKD3_k127_3112540_3 alcohol dehydrogenase - - - 0.000001052 51.0
HKD3_k127_3116066_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 356.0
HKD3_k127_3116066_1 outer membrane efflux protein - - - 0.00000000000000000000000000000001291 143.0
HKD3_k127_3116066_2 Histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000008078 97.0
HKD3_k127_3116066_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000008591 62.0
HKD3_k127_3116066_4 SpoVT / AbrB like domain - - - 0.00000001231 59.0
HKD3_k127_3122503_0 Belongs to the alpha-IPM synthase homocitrate synthase family - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 - 9.41e-208 655.0
HKD3_k127_3122503_1 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 361.0
HKD3_k127_3122503_2 inositol 2-dehydrogenase activity K16044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363 1.1.1.371 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 353.0
HKD3_k127_3122503_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000175 285.0
HKD3_k127_3122503_4 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000009738 218.0
HKD3_k127_3122503_5 Glucose-fructose oxidoreductase - - - 0.000000000000000000000000000000001464 142.0
HKD3_k127_3122503_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000001888 97.0
HKD3_k127_3122503_7 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0001561 44.0
HKD3_k127_3130917_0 transmembrane transporter activity K03296 - - 1.211e-274 866.0
HKD3_k127_3130917_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022 - - 0.0000000000000000000000000000000000000000005734 168.0
HKD3_k127_3131194_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate - - - 0.00000000000000000000000000000000000000000000000000003867 199.0
HKD3_k127_3154334_0 amino acid activation for nonribosomal peptide biosynthetic process K06113,K12685 - 3.2.1.99 0.0000000000000000000000000000000000000000000000000000000008418 224.0
HKD3_k127_3157618_0 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 524.0
HKD3_k127_3157618_1 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000002653 83.0
HKD3_k127_3160319_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 331.0
HKD3_k127_3160319_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 300.0
HKD3_k127_3160319_2 glycosyl transferase group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000001283 218.0
HKD3_k127_3178248_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000001486 209.0
HKD3_k127_3178248_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000002326 98.0
HKD3_k127_3178248_2 GyrI-like small molecule binding domain - - - 0.00000002744 66.0
HKD3_k127_3190845_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
HKD3_k127_3190845_1 PBS lyase HEAT-like repeat - - - 0.0004664 53.0
HKD3_k127_3194564_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 395.0
HKD3_k127_3194564_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000001905 211.0
HKD3_k127_3194564_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000001654 64.0
HKD3_k127_3206527_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 348.0
HKD3_k127_3206527_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000001401 226.0
HKD3_k127_3206527_2 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
HKD3_k127_3206527_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000274 94.0
HKD3_k127_3216467_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 342.0
HKD3_k127_3216467_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000000003779 114.0
HKD3_k127_3216467_2 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000004523 85.0
HKD3_k127_3224077_0 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000000000000000000000000000000000000000000001373 190.0
HKD3_k127_3224077_1 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000004393 151.0
HKD3_k127_3236661_0 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 422.0
HKD3_k127_3275220_0 Putative transposase - - - 2.526e-197 621.0
HKD3_k127_3275220_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 425.0
HKD3_k127_3281208_0 - - - - 0.00000000000000000004426 103.0
HKD3_k127_3295451_0 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000001711 188.0
HKD3_k127_3295451_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000002308 179.0
HKD3_k127_3295451_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000008614 68.0
HKD3_k127_3309219_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 400.0
HKD3_k127_3309219_1 AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002648 266.0
HKD3_k127_3309219_2 anti-sigma B factor K04757 - 2.7.11.1 0.00000000000000000000000427 106.0
HKD3_k127_3309219_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000008637 82.0
HKD3_k127_3309219_4 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.0000000001335 64.0
HKD3_k127_3310589_0 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000001474 125.0
HKD3_k127_3311974_0 PFAM peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 529.0
HKD3_k127_3311974_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
HKD3_k127_3311974_2 general secretion pathway protein K02456,K02679 - - 0.000000000000000000000000004891 118.0
HKD3_k127_3327075_0 Beta-galactosidase - - - 0.0000000000000000000000001404 119.0
HKD3_k127_3351491_0 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
HKD3_k127_3351491_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000002316 94.0
HKD3_k127_338012_0 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 524.0
HKD3_k127_338012_1 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000005842 127.0
HKD3_k127_3381005_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008659 267.0
HKD3_k127_3386201_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
HKD3_k127_3386201_2 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000002315 86.0
HKD3_k127_3411086_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 347.0
HKD3_k127_3411086_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 338.0
HKD3_k127_3426559_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 548.0
HKD3_k127_3426559_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000007411 235.0
HKD3_k127_3426559_2 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000004228 156.0
HKD3_k127_3430_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 345.0
HKD3_k127_3430_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 340.0
HKD3_k127_3443051_0 MmgE PrpD family protein K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 334.0
HKD3_k127_3443051_1 pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.0000000000000000000000000000000007026 136.0
HKD3_k127_3444523_0 - - - - 0.00000000000000000001796 100.0
HKD3_k127_3454700_0 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000002602 217.0
HKD3_k127_3469680_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 423.0
HKD3_k127_3469680_1 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000369 224.0
HKD3_k127_3469680_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000008966 143.0
HKD3_k127_347958_0 beta-N-acetylhexosaminidase activity - - - 0.0000000000000000000000000000000003362 151.0
HKD3_k127_350009_0 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 393.0
HKD3_k127_350009_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000001364 78.0
HKD3_k127_3506660_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 318.0
HKD3_k127_3506660_1 arylformamidase activity K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000002764 200.0
HKD3_k127_3506660_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000001205 184.0
HKD3_k127_3506660_3 Cytochrome P460 - - - 0.00000000000000000000000000000000000000001134 158.0
HKD3_k127_3506660_4 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000005716 115.0
HKD3_k127_3506660_5 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000001376 77.0
HKD3_k127_3507449_0 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0 1028.0
HKD3_k127_3507449_1 iron hydrogenase, small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 7.048e-252 791.0
HKD3_k127_3507449_2 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000003465 127.0
HKD3_k127_3516135_0 chelatase, subunit chli K06400,K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 547.0
HKD3_k127_3516135_1 Dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000008516 214.0
HKD3_k127_3516135_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000009682 191.0
HKD3_k127_3516135_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.00000000000000000000000000000000007201 135.0
HKD3_k127_3516135_4 Redoxin K03564 - 1.11.1.15 0.00000000000034 73.0
HKD3_k127_3516135_5 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.00000000004947 66.0
HKD3_k127_3519513_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 542.0
HKD3_k127_3519513_1 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000003241 122.0
HKD3_k127_3519513_2 KH domain K06960 - - 0.000000000000009754 76.0
HKD3_k127_3520524_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 384.0
HKD3_k127_3520524_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001464 272.0
HKD3_k127_3520524_2 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000004841 118.0
HKD3_k127_3525480_0 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001495 292.0
HKD3_k127_3525480_1 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000006352 189.0
HKD3_k127_3525480_2 regulatory protein, FmdB family - - - 0.0000000000000004479 80.0
HKD3_k127_3525480_3 Laminin G domain - - - 0.000000000001964 81.0
HKD3_k127_3528819_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000335 226.0
HKD3_k127_3528819_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000001144 222.0
HKD3_k127_3532621_0 MacB-like periplasmic core domain K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000002912 233.0
HKD3_k127_3532621_1 HlyD membrane-fusion protein of T1SS K02005,K13888 - - 0.00000000000000000000000000009068 132.0
HKD3_k127_3532621_2 COG0845 Membrane-fusion protein - - - 0.0000000000000001326 93.0
HKD3_k127_3532621_3 ABC transporter K02003 - - 0.000001995 50.0
HKD3_k127_3535182_0 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000005874 207.0
HKD3_k127_3535182_1 peptidyl-tyrosine sulfation - - - 0.0000000005462 70.0
HKD3_k127_3547203_0 PFAM Oligopeptide transporter OPT superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 608.0
HKD3_k127_3547203_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 284.0
HKD3_k127_3557082_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 356.0
HKD3_k127_3557082_1 PFAM Glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000003036 173.0
HKD3_k127_3557082_2 Ribonuclease R winged-helix domain protein K09720 - - 0.000000000000008306 76.0
HKD3_k127_3564874_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000001833 254.0
HKD3_k127_3564874_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000004286 141.0
HKD3_k127_3564874_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000005789 82.0
HKD3_k127_3569688_0 Tetratricopeptide repeat - - - 0.00000000000000000000005703 109.0
HKD3_k127_3574013_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 421.0
HKD3_k127_3574013_1 amidohydrolase - - - 0.000000000000000000000000000000000007446 143.0
HKD3_k127_357505_0 COG3119 Arylsulfatase A and related enzymes K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000001467 261.0
HKD3_k127_357505_1 exo-alpha-(2->6)-sialidase activity K01179 - 3.2.1.4 0.00000000000000000000000000006598 132.0
HKD3_k127_357505_2 Septum formation - - - 0.0000006769 56.0
HKD3_k127_3584950_0 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 428.0
HKD3_k127_3584950_1 Domain of unknown function DUF128 K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002802 257.0
HKD3_k127_3586133_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 483.0
HKD3_k127_3586133_1 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001308 258.0
HKD3_k127_3586133_2 Methyltransferase domain - - - 0.0001766 51.0
HKD3_k127_3596449_0 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 418.0
HKD3_k127_3596449_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000002602 274.0
HKD3_k127_3618867_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 541.0
HKD3_k127_3618867_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000002025 223.0
HKD3_k127_3618867_2 Rhamnan synthesis protein F K07272 - - 0.0000000000000000000000000000000000000000000000000003453 211.0
HKD3_k127_3618867_3 Glycosyl hydrolases family 2 K01192 - 3.2.1.25 0.0000000003175 73.0
HKD3_k127_3630352_0 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000001314 248.0
HKD3_k127_3630352_1 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000002568 180.0
HKD3_k127_3630352_2 FG-GAP repeat protein - - - 0.00000000000000000000000002509 125.0
HKD3_k127_3630352_3 Bacterial Ig-like domain - - - 0.0000000005939 73.0
HKD3_k127_3637851_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 392.0
HKD3_k127_3637851_1 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000545 147.0
HKD3_k127_3637851_2 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000005696 143.0
HKD3_k127_3637851_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000003599 108.0
HKD3_k127_3639167_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 322.0
HKD3_k127_3639167_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
HKD3_k127_3639167_2 Belongs to the MraZ family K03925 - - 0.000000000007236 74.0
HKD3_k127_3640692_0 Crp Fnr family K21564 - - 0.000000002859 66.0
HKD3_k127_3640692_1 N-acetylmuramoyl-L-alanine amidase - - - 0.00000001657 68.0
HKD3_k127_3640692_2 Crp-like helix-turn-helix domain - - - 0.00001955 52.0
HKD3_k127_3640692_3 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.0001466 52.0
HKD3_k127_3640692_4 cAMP-binding protein K10914,K21562 - - 0.0003748 51.0
HKD3_k127_3652352_0 - - - - 0.00000000000000000000000000000000000000000000000000004953 210.0
HKD3_k127_3679576_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 378.0
HKD3_k127_3679576_1 response to heat K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.00000000000000000000000000000000000000000000003646 175.0
HKD3_k127_3702388_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000001867 83.0
HKD3_k127_3702388_1 Biopolymer transport protein K03560 - - 0.000000000000001885 81.0
HKD3_k127_3702388_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000104 79.0
HKD3_k127_3718579_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 386.0
HKD3_k127_3718579_1 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000000000000000000000000000000000000000000004348 195.0
HKD3_k127_3730131_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000005833 232.0
HKD3_k127_3730131_2 LysM domain K06370 - - 0.0001623 49.0
HKD3_k127_3736083_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 353.0
HKD3_k127_3736083_1 exo-alpha-(2->6)-sialidase activity K01179,K01186 - 3.2.1.18,3.2.1.4 0.00000000000008397 82.0
HKD3_k127_3738043_0 polysaccharide deacetylase - - - 0.000000006051 66.0
HKD3_k127_3743677_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 529.0
HKD3_k127_3743677_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000001423 213.0
HKD3_k127_3764244_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 392.0
HKD3_k127_3764244_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
HKD3_k127_3764244_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000002082 121.0
HKD3_k127_3764244_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000003508 99.0
HKD3_k127_3764244_4 Histidine triad domain protein K02503 - - 0.000000000000000008923 83.0
HKD3_k127_3773097_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 469.0
HKD3_k127_3773097_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 344.0
HKD3_k127_3792169_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.219e-229 727.0
HKD3_k127_3792169_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000004097 201.0
HKD3_k127_3792169_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000001747 165.0
HKD3_k127_3792169_3 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000002453 57.0
HKD3_k127_380854_0 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 396.0
HKD3_k127_380854_1 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 325.0
HKD3_k127_380854_2 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000001015 255.0
HKD3_k127_380854_3 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000002023 215.0
HKD3_k127_3828436_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 289.0
HKD3_k127_3828436_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000001227 134.0
HKD3_k127_3832963_0 Beta-galactosidase K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000002484 226.0
HKD3_k127_3832963_1 translation initiation factor activity K02945,K08086,K08300,K08301,K20276 - 3.1.26.12 0.0000000000000000002698 94.0
HKD3_k127_3832963_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.00000000002252 78.0
HKD3_k127_3832963_3 domain protein K20276 - - 0.0001037 48.0
HKD3_k127_3834500_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 3.716e-199 629.0
HKD3_k127_3834500_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 494.0
HKD3_k127_3834500_2 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000007618 252.0
HKD3_k127_3834500_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000002631 121.0
HKD3_k127_3840255_0 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
HKD3_k127_3852991_0 Cytochrome b subunit of the bc K00412,K02635 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001104 246.0
HKD3_k127_3852991_1 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
HKD3_k127_3852991_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000009426 226.0
HKD3_k127_3852991_3 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000000000002645 211.0
HKD3_k127_3852991_4 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000004438 101.0
HKD3_k127_3852991_5 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000002986 95.0
HKD3_k127_3865698_0 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 389.0
HKD3_k127_3871654_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 468.0
HKD3_k127_3871654_1 ribulokinase activity - - - 0.0000000000000000004564 90.0
HKD3_k127_3871654_2 Protein of unknown function (DUF402) K09145 - - 0.00002898 55.0
HKD3_k127_3871654_3 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.0009664 49.0
HKD3_k127_3873124_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003328 270.0
HKD3_k127_3873124_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000000000000000000000000000000000000000002504 181.0
HKD3_k127_3888263_0 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 249.0
HKD3_k127_3888263_1 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000000000000000005222 211.0
HKD3_k127_3888263_2 ioli protein K06606 - 5.3.99.11 0.00000000000000000002779 93.0
HKD3_k127_3888263_3 Xylulose 5-phosphate 3-epimerase K03079 - 5.1.3.22 0.0000000000002022 72.0
HKD3_k127_3888263_4 PFAM AMMECR1 domain protein K09141 - - 0.000000000004853 74.0
HKD3_k127_3898374_0 Polymorphic membrane protein Chlamydia - - - 0.000000000000000000000000000000000000000000000000506 193.0
HKD3_k127_3904953_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1027.0
HKD3_k127_3904953_1 Male sterility protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000002871 247.0
HKD3_k127_3904953_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000004432 136.0
HKD3_k127_3904953_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000005222 137.0
HKD3_k127_3904953_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000297 104.0
HKD3_k127_3904953_5 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000005304 61.0
HKD3_k127_3904953_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00002678 52.0
HKD3_k127_390863_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 437.0
HKD3_k127_390863_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000003832 216.0
HKD3_k127_390863_2 PFAM Radical SAM - - - 0.00000000000005654 72.0
HKD3_k127_3912002_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 456.0
HKD3_k127_3914941_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000004888 200.0
HKD3_k127_3914941_1 pfam php K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000019 194.0
HKD3_k127_3917677_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005628 271.0
HKD3_k127_3917677_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000006871 169.0
HKD3_k127_393694_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005408 264.0
HKD3_k127_393694_1 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000668 131.0
HKD3_k127_393694_2 signal transduction histidine kinase - - - 0.00000000000000000000000007045 115.0
HKD3_k127_393694_3 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.0000000000000000000006729 107.0
HKD3_k127_393694_4 deoxyhypusine monooxygenase activity - - - 0.00000000000000000006286 104.0
HKD3_k127_393694_5 ACT domain - - - 0.00000000000000626 81.0
HKD3_k127_396493_0 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 371.0
HKD3_k127_396493_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000006804 142.0
HKD3_k127_396493_2 Belongs to the Nudix hydrolase family K18445 - 3.6.1.61 0.000000000000000000002918 98.0
HKD3_k127_396493_3 Glycosyl transferases group 1 - - - 0.0000000000000008819 90.0
HKD3_k127_3967786_0 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane K02761 - - 0.0000000000000000000000000000000000000000001073 166.0
HKD3_k127_3967786_1 - - - - 0.00000000000000000000000000001596 123.0
HKD3_k127_3978389_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000001983 91.0
HKD3_k127_3978389_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000007703 81.0
HKD3_k127_3978389_2 - - - - 0.00000003994 66.0
HKD3_k127_3980289_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000005895 87.0
HKD3_k127_3980289_1 exo-alpha-(2->6)-sialidase activity - - - 0.000001525 60.0
HKD3_k127_3987969_0 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 323.0
HKD3_k127_3987969_1 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000268 153.0
HKD3_k127_3987969_2 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000004271 81.0
HKD3_k127_3990122_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000004672 235.0
HKD3_k127_3990122_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000005422 59.0
HKD3_k127_3990122_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000001013 68.0
HKD3_k127_3992560_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005506 231.0
HKD3_k127_3992560_1 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000001132 141.0
HKD3_k127_3994261_0 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 421.0
HKD3_k127_3994261_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 302.0
HKD3_k127_3994261_2 acetyl-CoA hydrolase transferase - - - 0.0000000000000001436 82.0
HKD3_k127_4013526_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 366.0
HKD3_k127_4013526_1 Glutaredoxin K03676 - - 0.000000000955 61.0
HKD3_k127_4013526_2 competence protein - - - 0.0000007005 54.0
HKD3_k127_403051_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 365.0
HKD3_k127_403051_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000586 120.0
HKD3_k127_403051_2 Stage II sporulation protein K06381 - - 0.0000000000000000000000002551 113.0
HKD3_k127_403051_3 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000007121 112.0
HKD3_k127_403051_4 general secretion pathway protein K02456,K02650,K02679 - - 0.000000000000000000003644 102.0
HKD3_k127_4032516_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 255.0
HKD3_k127_4032516_1 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000005812 177.0
HKD3_k127_4032516_2 Acetyltransferase (GNAT) family K06976 - - 0.000000000000000000108 94.0
HKD3_k127_4032516_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000001595 63.0
HKD3_k127_4060921_0 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000000000000000000003473 233.0
HKD3_k127_4076953_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005705 258.0
HKD3_k127_4076953_1 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000001523 112.0
HKD3_k127_4076953_2 - - - - 0.000000000000005557 78.0
HKD3_k127_4080924_0 Transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000007187 145.0
HKD3_k127_4080924_1 - - - - 0.00000000000000003711 86.0
HKD3_k127_4080924_2 Psort location Cytoplasmic, score 8.96 - - - 0.000000006279 61.0
HKD3_k127_4084968_0 - - - - 0.00000000000000000000000000000000000001723 152.0
HKD3_k127_4084968_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000007914 98.0
HKD3_k127_4096221_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 345.0
HKD3_k127_4096221_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000006908 263.0
HKD3_k127_4096221_2 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000008184 196.0
HKD3_k127_4096221_3 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000001558 135.0
HKD3_k127_409761_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 415.0
HKD3_k127_409761_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 361.0
HKD3_k127_409761_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000009477 107.0
HKD3_k127_409761_3 Domain of unknown function (DUF4342) - - - 0.00000001649 63.0
HKD3_k127_409761_4 COG0457 FOG TPR repeat - - - 0.0004034 51.0
HKD3_k127_411151_0 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 410.0
HKD3_k127_4129130_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
HKD3_k127_4129130_1 outer membrane efflux protein - - - 0.00000000000000000000000000000000000002104 160.0
HKD3_k127_4142493_0 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000001249 61.0
HKD3_k127_4142493_1 Cyclic nucleotide-monophosphate binding domain - - - 0.0000351 54.0
HKD3_k127_4172841_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 426.0
HKD3_k127_4177501_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 400.0
HKD3_k127_4177501_1 guanyl-nucleotide exchange factor activity K01181,K20276 - 3.2.1.8 0.000000000000000000001128 102.0
HKD3_k127_4192444_0 Right handed beta helix region - - - 0.00000000000000000000018 111.0
HKD3_k127_4203595_0 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 312.0
HKD3_k127_4203595_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000002204 194.0
HKD3_k127_4203595_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000009726 118.0
HKD3_k127_4203595_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000003119 112.0
HKD3_k127_4203595_4 Protein conserved in bacteria K11719 - - 0.00004851 54.0
HKD3_k127_4203595_5 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.0009183 48.0
HKD3_k127_4210126_0 4 iron, 4 sulfur cluster binding - - - 0.0 1039.0
HKD3_k127_4219144_0 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 516.0
HKD3_k127_4219144_1 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000009463 233.0
HKD3_k127_4219144_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000347 149.0
HKD3_k127_4219144_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000007023 139.0
HKD3_k127_4219144_4 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000001406 135.0
HKD3_k127_4219144_5 Histidine kinase - - - 0.0000000000000000000000209 106.0
HKD3_k127_4241386_0 - - - - 0.0000000000000668 84.0
HKD3_k127_4241386_1 - - - - 0.000003942 55.0
HKD3_k127_4252_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.23e-206 662.0
HKD3_k127_4252_1 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000006211 216.0
HKD3_k127_4252_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001428 118.0
HKD3_k127_4252_3 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000000000001234 78.0
HKD3_k127_4252_4 Protein of unknown function (DUF503) K09764 - - 0.00000000002707 70.0
HKD3_k127_426918_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 439.0
HKD3_k127_426918_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007615 275.0
HKD3_k127_426918_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000002528 239.0
HKD3_k127_426918_3 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000006682 213.0
HKD3_k127_426918_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000004964 218.0
HKD3_k127_426918_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00006113 49.0
HKD3_k127_4273750_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 354.0
HKD3_k127_4273750_1 Acts as a magnesium transporter K03886 - - 0.00000000000000000000000000000000000000000000000000000000000005153 218.0
HKD3_k127_4282065_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 396.0
HKD3_k127_4282065_1 PFAM response regulator receiver K22010 - - 0.0000000000000000000000000002607 118.0
HKD3_k127_4282563_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 298.0
HKD3_k127_4282563_1 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002706 268.0
HKD3_k127_4282563_2 Acetyltransferase (GNAT) domain K03395 - 2.3.1.60 0.000000000000008873 79.0
HKD3_k127_4292158_0 adhesin AidA-related - - - 0.000000001038 70.0
HKD3_k127_4292158_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000003884 52.0
HKD3_k127_431439_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 533.0
HKD3_k127_431439_1 polysaccharide catabolic process - - - 0.000000000000000000000001301 120.0
HKD3_k127_4327640_0 mismatched DNA binding K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.223e-236 752.0
HKD3_k127_4327640_1 PFAM PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000625 116.0
HKD3_k127_4332848_0 TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 477.0
HKD3_k127_4332848_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000001676 212.0
HKD3_k127_4332848_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000004053 68.0
HKD3_k127_4332848_3 PFAM GGDEF domain containing protein - - - 0.000000006114 67.0
HKD3_k127_4333520_0 serine threonine protein kinase - - - 0.0000007086 54.0
HKD3_k127_4343398_0 cell shape determining protein, MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 394.0
HKD3_k127_4343398_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 354.0
HKD3_k127_4343398_2 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 314.0
HKD3_k127_4343398_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000007392 172.0
HKD3_k127_4343398_4 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000003594 127.0
HKD3_k127_4343398_5 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000004668 118.0
HKD3_k127_4343398_6 granule-associated protein - - - 0.00000000001861 68.0
HKD3_k127_4358661_0 Belongs to the carbamoyltransferase HypF family K04656 - - 3.22e-233 744.0
HKD3_k127_4358661_1 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 581.0
HKD3_k127_4358661_10 HupF/HypC family K04653 - - 0.0000001513 59.0
HKD3_k127_4358661_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 421.0
HKD3_k127_4358661_3 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 393.0
HKD3_k127_4358661_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 257.0
HKD3_k127_4358661_5 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001379 253.0
HKD3_k127_4358661_6 Belongs to the complex I 20 kDa subunit family - - - 0.000000000000000000000000000000000000000000000000000000000000001238 223.0
HKD3_k127_4358661_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000000000000000001938 175.0
HKD3_k127_4358661_8 OsmC-like protein - - - 0.000000000000000000000000000000000002154 148.0
HKD3_k127_4358661_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000001038 78.0
HKD3_k127_4366994_0 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000001229 265.0
HKD3_k127_4366994_1 Arylsulfotransferase (ASST) - - - 0.0001499 45.0
HKD3_k127_4371773_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 467.0
HKD3_k127_4378183_0 Protein of unknown function (DUF229) - - - 1.289e-202 643.0
HKD3_k127_4378183_1 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000007639 162.0
HKD3_k127_4378183_2 - - - - 0.0000000000000000000000000000000001142 150.0
HKD3_k127_4378183_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.0000001694 63.0
HKD3_k127_4381299_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000002882 186.0
HKD3_k127_4381299_1 Protein of unknown function (DUF2961) - - - 0.00000000000000007232 87.0
HKD3_k127_4385177_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 385.0
HKD3_k127_4385177_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
HKD3_k127_4385177_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000003379 195.0
HKD3_k127_439082_0 COG3119 Arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000000004523 194.0
HKD3_k127_439082_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19668 - 3.2.1.91 0.0001367 53.0
HKD3_k127_4395654_0 Virulence factor Mce family protein K02067 - - 0.000000004354 64.0
HKD3_k127_4395654_1 alginic acid biosynthetic process - - - 0.000000009505 67.0
HKD3_k127_4430206_0 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 371.0
HKD3_k127_4430206_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 308.0
HKD3_k127_4430206_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000001647 211.0
HKD3_k127_4430206_3 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000000000000000002048 146.0
HKD3_k127_4435222_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000002251 169.0
HKD3_k127_4435222_1 acr, cog1399 K07040 - - 0.00000000000000000000000000001201 125.0
HKD3_k127_4435222_2 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000008583 81.0
HKD3_k127_4435222_3 Ig domain protein group 2 domain protein - - - 0.00003235 57.0
HKD3_k127_4445113_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 422.0
HKD3_k127_4445113_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000001918 174.0
HKD3_k127_445273_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000001491 115.0
HKD3_k127_445596_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000002463 217.0
HKD3_k127_445596_1 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000008509 209.0
HKD3_k127_445596_2 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000004299 204.0
HKD3_k127_445596_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000006792 171.0
HKD3_k127_445596_4 DNA polymerase III, delta K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0003497 47.0
HKD3_k127_4457916_0 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 302.0
HKD3_k127_4457916_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003187 256.0
HKD3_k127_4457916_2 PFAM Nucleoside recognition - - - 0.00000000005126 66.0
HKD3_k127_4480680_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000007493 244.0
HKD3_k127_4480680_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000001067 171.0
HKD3_k127_4480680_2 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.000000000000000939 86.0
HKD3_k127_4480680_3 Type II secretion system (T2SS), protein M K02664 - - 0.000001398 59.0
HKD3_k127_4480680_4 COG3166 Tfp pilus assembly protein PilN K02663 - - 0.0001926 51.0
HKD3_k127_4480680_5 type IV pilus secretin PilQ K02666 - - 0.0002304 51.0
HKD3_k127_4501017_0 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 388.0
HKD3_k127_4501017_1 Ferredoxin K05337 - - 0.0000000000000316 75.0
HKD3_k127_4528160_0 beta-1,4-mannooligosaccharide phosphorylase K18785 - 2.4.1.319,2.4.1.320 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 405.0
HKD3_k127_4528160_1 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000004394 206.0
HKD3_k127_4551175_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 310.0
HKD3_k127_4551175_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001211 280.0
HKD3_k127_4551175_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000225 140.0
HKD3_k127_4551945_0 PFAM D-Lysine 5,6-aminomutase alpha subunit K01844 - 5.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 540.0
HKD3_k127_4551945_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 497.0
HKD3_k127_4551945_2 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 301.0
HKD3_k127_4551945_3 PFAM cobalamin B12-binding domain protein K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
HKD3_k127_4551945_4 - - - - 0.000000000000000000000000000000008568 137.0
HKD3_k127_4564807_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 289.0
HKD3_k127_4564807_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000003044 251.0
HKD3_k127_4566263_0 Evidence 5 No homology to any previously reported sequences K03088 - - 0.000000000000000000000000000000007757 147.0
HKD3_k127_4595922_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000001666 271.0
HKD3_k127_4595922_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000001043 217.0
HKD3_k127_4595922_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000004889 187.0
HKD3_k127_4595922_3 ABC transporter K01990 - - 0.000000000000000000001757 96.0
HKD3_k127_4595922_4 methyltransferase activity - - - 0.000000000000006383 79.0
HKD3_k127_4598810_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 565.0
HKD3_k127_4599092_0 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate) K03337 - 5.3.1.30 0.0000000000000000000000000000000000004119 146.0
HKD3_k127_4599092_1 - - - - 0.0000005431 62.0
HKD3_k127_4604567_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 544.0
HKD3_k127_4604567_1 Type II IV secretion system protein K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 508.0
HKD3_k127_4604567_2 DNA binding domain, excisionase family - - - 0.000000000000004083 76.0
HKD3_k127_4604567_3 SMART Transport-associated and nodulation region - - - 0.0005673 46.0
HKD3_k127_4605235_0 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 346.0
HKD3_k127_4617035_0 PFAM Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 509.0
HKD3_k127_4617035_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000007423 269.0
HKD3_k127_4619116_0 Cytochrome c biogenesis protein K06196 - - 0.000000000000000002002 89.0
HKD3_k127_4619116_1 Protein kinase domain - - - 0.0006503 50.0
HKD3_k127_4623550_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 346.0
HKD3_k127_4623550_1 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 352.0
HKD3_k127_4623550_2 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000004614 154.0
HKD3_k127_4623550_3 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.00000000000000000000000000000001102 135.0
HKD3_k127_4623550_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000001722 123.0
HKD3_k127_4623550_5 TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2 - - - 0.000000000004815 77.0
HKD3_k127_4627930_0 Glycosyl hydrolase family 20, domain 2 - - - 0.000185 54.0
HKD3_k127_4642874_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000009514 158.0
HKD3_k127_4642874_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0002632 55.0
HKD3_k127_4644205_0 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000741 237.0
HKD3_k127_4644205_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000002396 112.0
HKD3_k127_4644205_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000001718 97.0
HKD3_k127_4644205_3 CAAX protease self-immunity K07052 - - 0.0000000000000233 85.0
HKD3_k127_4649050_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 317.0
HKD3_k127_4649050_1 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000000000000000000000000000006698 198.0
HKD3_k127_4649050_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000002676 174.0
HKD3_k127_4652359_0 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 372.0
HKD3_k127_4652551_0 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000294 104.0
HKD3_k127_4652551_1 UvrD REP helicase - - - 0.0000000002078 72.0
HKD3_k127_4653917_0 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 319.0
HKD3_k127_4653917_1 BNR repeat-like domain K01186 - 3.2.1.18 0.00000000000000000000000000000000004567 141.0
HKD3_k127_4663005_0 Sugar ABC transporter permease K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006071 259.0
HKD3_k127_4663005_1 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000001579 236.0
HKD3_k127_4663005_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000002421 75.0
HKD3_k127_4682401_0 Carbohydrate-binding family 9 - - - 0.0000000000322 70.0
HKD3_k127_4694792_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 366.0
HKD3_k127_4694792_1 ATP citrate lyase citrate-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007558 273.0
HKD3_k127_4694792_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000002436 203.0
HKD3_k127_4694792_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.000000000000000000000000000000000000000000000000001959 192.0
HKD3_k127_4694792_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000001822 119.0
HKD3_k127_4694792_5 Periplasmic or secreted lipoprotein - - - 0.0000000000000000000001918 98.0
HKD3_k127_4711608_0 Polymorphic membrane protein Chlamydia - - - 0.000000000000000000000000000000000000000000000000000000001327 222.0
HKD3_k127_4715327_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000705 130.0
HKD3_k127_4745671_0 Transketolase, pyrimidine binding domain K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 359.0
HKD3_k127_4745671_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 345.0
HKD3_k127_4745671_2 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000000000000000000002361 155.0
HKD3_k127_4745671_3 Prolyl oligopeptidase family K06889 - - 0.000000000004629 68.0
HKD3_k127_4745671_4 acyl carrier protein K02078 - - 0.0000000004938 63.0
HKD3_k127_4749098_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000005133 197.0
HKD3_k127_4749098_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000005366 158.0
HKD3_k127_4749098_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000001414 132.0
HKD3_k127_4749098_3 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000001956 54.0
HKD3_k127_4757194_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.301e-294 921.0
HKD3_k127_4757194_1 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 466.0
HKD3_k127_4757194_2 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 430.0
HKD3_k127_4757194_3 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 357.0
HKD3_k127_4757194_4 Formyl transferase, C-terminal domain K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 307.0
HKD3_k127_4757194_5 PFAM AsnC family - - - 0.00000000000000000000000000000000000000000000000001572 184.0
HKD3_k127_4757194_6 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000001093 143.0
HKD3_k127_4757194_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000007003 117.0
HKD3_k127_4757194_8 PFAM BioY family K03523 - - 0.000000000000000000000000008995 124.0
HKD3_k127_4779403_0 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 431.0
HKD3_k127_4779403_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002353 278.0
HKD3_k127_4784361_0 Aminoglycoside phosphotransferase - - - 0.000000005697 61.0
HKD3_k127_4792286_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 622.0
HKD3_k127_4792286_1 ABC-type multidrug transport system ATPase K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000008022 236.0
HKD3_k127_4792286_2 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000002482 184.0
HKD3_k127_4792286_3 iron ion homeostasis K03709,K04758,K09819 - - 0.00000000000000000000000000000000000014 150.0
HKD3_k127_4792286_4 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000001163 108.0
HKD3_k127_4792286_5 general secretion pathway protein K02456,K02650,K02679 - - 0.0000000000000001835 80.0
HKD3_k127_4813651_0 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 377.0
HKD3_k127_4813651_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 337.0
HKD3_k127_4813651_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000003875 159.0
HKD3_k127_4813651_3 Cytochrome c K01256 - 3.4.11.2 0.000000000000000000003221 110.0
HKD3_k127_4813651_4 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000006878 77.0
HKD3_k127_4822389_0 BNR repeat-containing family member - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 504.0
HKD3_k127_4822648_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
HKD3_k127_4822648_1 Domain of unknown function (DUF4838) - - - 0.000000000000000000000000000000000000000000000000000000000000004147 237.0
HKD3_k127_4823707_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000003643 178.0
HKD3_k127_4823707_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000004481 139.0
HKD3_k127_4823707_2 TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2 - - - 0.00000000001664 78.0
HKD3_k127_4844811_0 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 413.0
HKD3_k127_4844811_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 363.0
HKD3_k127_4844811_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 323.0
HKD3_k127_4844811_3 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 290.0
HKD3_k127_4844811_4 beta-N-acetylglucosaminidase K01197 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 3.2.1.35 0.0003533 51.0
HKD3_k127_485549_0 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 424.0
HKD3_k127_4856038_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000001641 119.0
HKD3_k127_4856038_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000001996 79.0
HKD3_k127_4856038_2 Putative zinc-finger - - - 0.0006326 49.0
HKD3_k127_4878976_0 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 414.0
HKD3_k127_4878976_1 Domain of unknown function (DUF4091) - - - 0.000000000000000000000000000000000007014 148.0
HKD3_k127_4887677_0 PFAM Glucose-inhibited division protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 451.0
HKD3_k127_4887677_1 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000001225 146.0
HKD3_k127_4887677_2 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106 - 4.2.1.126 0.0001178 46.0
HKD3_k127_4888800_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 385.0
HKD3_k127_4888800_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 334.0
HKD3_k127_4888800_2 phosphorelay signal transduction system K07315 - 3.1.3.3 0.000000000000000000000000000000000000003306 151.0
HKD3_k127_489416_0 DNA-templated transcription, initiation K03088 - - 0.000000000003718 72.0
HKD3_k127_4901312_0 Domain of unknown function (DUF5060) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
HKD3_k127_4901312_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000004813 163.0
HKD3_k127_4937924_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000008869 217.0
HKD3_k127_4937924_1 NTPase K06928 - 3.6.1.15 0.00000001459 61.0
HKD3_k127_4946582_0 - - - - 0.0000000000001891 81.0
HKD3_k127_4946582_1 - - - - 0.000000003612 61.0
HKD3_k127_4980954_0 arabinan catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004113 252.0
HKD3_k127_4980954_1 PFAM Acetyl-CoA hydrolase transferase - - - 0.000000000000000000000008015 106.0
HKD3_k127_4991104_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 545.0
HKD3_k127_4991104_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 496.0
HKD3_k127_4991104_2 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006803 241.0
HKD3_k127_4991104_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000006975 117.0
HKD3_k127_4997365_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1183.0
HKD3_k127_4997365_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000003154 72.0
HKD3_k127_5017622_0 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 586.0
HKD3_k127_5017622_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 469.0
HKD3_k127_5017622_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001174 273.0
HKD3_k127_5017622_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000007547 214.0
HKD3_k127_5017622_4 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000000009924 201.0
HKD3_k127_5017622_5 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000000000000000001114 183.0
HKD3_k127_5017622_6 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000001958 163.0
HKD3_k127_5017622_7 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000004244 64.0
HKD3_k127_5017622_8 thiolester hydrolase activity K06889 - - 0.000000304 63.0
HKD3_k127_5017622_9 Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate K01222 - 3.2.1.86 0.0001175 47.0
HKD3_k127_5029778_0 methyltransferase small K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000003044 218.0
HKD3_k127_5029778_1 protein conserved in bacteria K09992 - - 0.000000000000000000000000002316 115.0
HKD3_k127_5029778_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000002878 113.0
HKD3_k127_5046931_0 FG-GAP repeat - - - 0.00000000002857 76.0
HKD3_k127_5046931_1 Protein conserved in bacteria - - - 0.00000005472 65.0
HKD3_k127_5054232_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000277 177.0
HKD3_k127_507633_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 323.0
HKD3_k127_507633_1 Glycosyl hydrolase family 57 K22278 - 3.5.1.104 0.0000000000000000000000000000000000000002535 162.0
HKD3_k127_5098244_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 555.0
HKD3_k127_5098244_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 333.0
HKD3_k127_5110662_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 617.0
HKD3_k127_5132835_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 451.0
HKD3_k127_5132835_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000006799 94.0
HKD3_k127_5132835_2 membrane - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000004023 96.0
HKD3_k127_5152932_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 525.0
HKD3_k127_5152932_1 protein transport across the cell outer membrane K02455,K02653,K12278 - - 0.00000000000000000000000000000000000000000000000000000003295 205.0
HKD3_k127_5152932_2 Type II secretion system (T2SS), protein F K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.000000000000000000000000000005433 123.0
HKD3_k127_5152932_3 general secretion pathway protein K02456,K02650 - - 0.00000000000000003545 86.0
HKD3_k127_5179929_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000657 164.0
HKD3_k127_5179929_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.00000000000000000000000000004257 119.0
HKD3_k127_5183860_0 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000000000006845 93.0
HKD3_k127_5188260_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001928 254.0
HKD3_k127_5188260_1 Pkd domain containing protein - - - 0.000002635 60.0
HKD3_k127_5213037_0 ABC transporter B family member K02114,K05658 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.44 0.0000000000000000000000000000000000000000000000000000000000000036 222.0
HKD3_k127_5213037_1 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
HKD3_k127_5213037_2 DsrE/DsrF-like family K06039 - - 0.000000000000000000008013 98.0
HKD3_k127_5213037_3 G8 - - - 0.00003804 53.0
HKD3_k127_5213679_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000006448 121.0
HKD3_k127_5251975_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000005103 154.0
HKD3_k127_5251975_1 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000006774 112.0
HKD3_k127_5251975_2 cell adhesion K02650 - - 0.00000000000000000000002336 108.0
HKD3_k127_5256458_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
HKD3_k127_5256458_1 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.00000000000000008951 87.0
HKD3_k127_5257282_0 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.000000000000000000000000008853 121.0
HKD3_k127_5257282_1 alpha beta - - - 0.0000000000000001521 91.0
HKD3_k127_5320625_0 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 336.0
HKD3_k127_5320625_1 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003845 220.0
HKD3_k127_5320625_2 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000008238 163.0
HKD3_k127_532299_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 454.0
HKD3_k127_532299_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 349.0
HKD3_k127_532299_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
HKD3_k127_532299_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
HKD3_k127_532299_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000002822 106.0
HKD3_k127_5334630_0 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 306.0
HKD3_k127_5334630_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000321 237.0
HKD3_k127_5334630_2 MOSC domain - - - 0.000000000000000000000000000000000000000003053 160.0
HKD3_k127_5334630_3 Type ii and iii secretion system protein K02453,K02666 - - 0.000004053 57.0
HKD3_k127_5357915_0 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 323.0
HKD3_k127_5357915_1 Glycosyl-hydrolase family 116, catalytic region - - - 0.00000000000000058 89.0
HKD3_k127_5372203_0 PFAM Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 323.0
HKD3_k127_5372203_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000007291 166.0
HKD3_k127_5372203_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000004328 62.0
HKD3_k127_5395404_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000009693 235.0
HKD3_k127_5395404_1 Amidohydrolase K07045 - - 0.00000000000000002034 85.0
HKD3_k127_5395404_2 creatininase K01470 - 3.5.2.10 0.000000000000001895 78.0
HKD3_k127_5395404_3 - - - - 0.00000008204 61.0
HKD3_k127_5410409_0 Trehalase K03931 - - 0.000000000000000000000000000000000000000000000004646 187.0
HKD3_k127_5410409_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000002652 132.0
HKD3_k127_5410409_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000009593 115.0
HKD3_k127_5414886_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 373.0
HKD3_k127_5418365_0 Domain of unknown function (DUF4976) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 597.0
HKD3_k127_5418365_1 Phospholipid methyltransferase - - - 0.0000000000000000000000000007168 119.0
HKD3_k127_5418365_2 SUKH-4 immunity protein - - - 0.0000000000000000000007461 102.0
HKD3_k127_5418365_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000002814 88.0
HKD3_k127_5443117_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000007108 143.0
HKD3_k127_5456276_0 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000001321 198.0
HKD3_k127_5458935_0 Outer membrane protein, OMP85 family K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 336.0
HKD3_k127_5458935_1 lipid A biosynthetic process K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 308.0
HKD3_k127_5458935_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000001374 122.0
HKD3_k127_5458935_3 Outer membrane protein (OmpH-like) K06142 - - 0.0009782 49.0
HKD3_k127_5471310_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 504.0
HKD3_k127_5471310_1 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000005796 222.0
HKD3_k127_5472115_0 self proteolysis - - - 0.000000000237 72.0
HKD3_k127_5483697_0 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000952 240.0
HKD3_k127_5487326_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002502 229.0
HKD3_k127_5487326_2 methyltransferase - - - 0.00000000000000000000000000000000002559 144.0
HKD3_k127_5502024_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 388.0
HKD3_k127_5502024_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001415 270.0
HKD3_k127_5502024_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
HKD3_k127_5502024_3 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000007392 176.0
HKD3_k127_550754_0 3-deoxy-7-phosphoheptulonate synthase activity K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 403.0
HKD3_k127_550754_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 387.0
HKD3_k127_550754_2 nucleic acid binding K03698 - - 0.000000000000000000000000000000000000000002629 160.0
HKD3_k127_5527464_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000004875 223.0
HKD3_k127_5527464_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000008257 192.0
HKD3_k127_5527464_2 Belongs to the glycosyl hydrolase 67 family - - - 0.00000000000000001092 98.0
HKD3_k127_5563413_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 608.0
HKD3_k127_5563413_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000002137 56.0
HKD3_k127_5563413_2 - - - - 0.00000002218 63.0
HKD3_k127_5567031_0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00239 - 1.3.5.1,1.3.5.4 1.569e-238 761.0
HKD3_k127_5567031_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000303 196.0
HKD3_k127_5567031_2 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000005233 115.0
HKD3_k127_5567031_4 - - - - 0.000000002453 63.0
HKD3_k127_5572158_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 524.0
HKD3_k127_5572158_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K05565 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 532.0
HKD3_k127_5572158_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000005613 201.0
HKD3_k127_5572158_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000002371 115.0
HKD3_k127_5572158_4 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000007866 109.0
HKD3_k127_5572158_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000001515 94.0
HKD3_k127_5572158_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000007673 84.0
HKD3_k127_5576687_0 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 323.0
HKD3_k127_5576687_1 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 336.0
HKD3_k127_5576687_2 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005145 282.0
HKD3_k127_5576687_3 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000202 230.0
HKD3_k127_5581843_0 Xylose isomerase - - - 0.0000000000000000000000000000006713 133.0
HKD3_k127_5581843_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000007518 97.0
HKD3_k127_5599927_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 422.0
HKD3_k127_5599927_1 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.00000000000000000000000000002962 120.0
HKD3_k127_5599927_2 type IV pilus secretin PilQ K02666 - - 0.0003338 46.0
HKD3_k127_560137_0 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 272.0
HKD3_k127_560137_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000001443 237.0
HKD3_k127_560137_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000005785 90.0
HKD3_k127_5623286_0 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 0.0 1469.0
HKD3_k127_5623286_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.818e-320 992.0
HKD3_k127_5623286_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.384e-205 645.0
HKD3_k127_5623286_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000005795 219.0
HKD3_k127_5623286_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000005585 204.0
HKD3_k127_5652595_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000004203 119.0
HKD3_k127_5667817_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000462 166.0
HKD3_k127_5667817_1 general secretion pathway protein K02456,K02679 - - 0.0000000000000000000001408 105.0
HKD3_k127_5667817_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000002172 94.0
HKD3_k127_5667817_3 general secretion pathway protein K02456,K02679 - - 0.00000000000000000002207 99.0
HKD3_k127_5667817_4 general secretion pathway protein K02456,K02679 - - 0.000000000000000003173 92.0
HKD3_k127_5667817_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000002091 73.0
HKD3_k127_5695331_0 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 327.0
HKD3_k127_5695331_1 O-GlcNAcase BT_4395 K01197 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 3.2.1.35 0.00000000000000000000000000000000007058 147.0
HKD3_k127_5697135_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 308.0
HKD3_k127_5697135_1 Domain of unknown function (DUF1844) - - - 0.0000000002456 66.0
HKD3_k127_5697135_2 - - - - 0.0002699 44.0
HKD3_k127_5711083_0 PFAM Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000002149 167.0
HKD3_k127_5711083_1 MobA-like NTP transferase domain - - - 0.0000000000001695 73.0
HKD3_k127_5711083_2 - - - - 0.000000000414 61.0
HKD3_k127_5732885_0 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0000000000000000000000000000067 139.0
HKD3_k127_5732885_1 alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 0.0000000000000000000000000008354 130.0
HKD3_k127_5732885_2 antibiotic catabolic process K13277 - - 0.00006632 53.0
HKD3_k127_5736034_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 565.0
HKD3_k127_5736034_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 502.0
HKD3_k127_5736034_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000008071 260.0
HKD3_k127_5749376_0 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
HKD3_k127_5749376_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000001611 190.0
HKD3_k127_5749376_2 Aldo/keto reductase family - - - 0.0000000000000000000000003912 108.0
HKD3_k127_5754262_0 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 391.0
HKD3_k127_5754262_1 self proteolysis - - - 0.0000000000000000000000000000000006731 151.0
HKD3_k127_5754262_2 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.00000000000000000000000001003 116.0
HKD3_k127_5758350_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 467.0
HKD3_k127_5758350_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000987 225.0
HKD3_k127_5758350_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000003603 177.0
HKD3_k127_5767686_0 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 551.0
HKD3_k127_5767686_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HKD3_k127_5767686_2 negative regulation of translational initiation K05554,K15885 - - 0.00000000000000000000000000000000004057 140.0
HKD3_k127_5767686_3 - - - - 0.0001562 45.0
HKD3_k127_5771280_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 368.0
HKD3_k127_5771280_1 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000000185 214.0
HKD3_k127_5773438_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.222e-241 759.0
HKD3_k127_5773438_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 548.0
HKD3_k127_5789053_0 DNA polymerase X family K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 586.0
HKD3_k127_5789053_1 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000001871 244.0
HKD3_k127_5789053_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000005199 219.0
HKD3_k127_5789053_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000009016 207.0
HKD3_k127_5789053_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000002453 110.0
HKD3_k127_5789053_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000005004 100.0
HKD3_k127_5789611_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 352.0
HKD3_k127_5789611_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 349.0
HKD3_k127_5789611_2 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000009163 148.0
HKD3_k127_5795203_0 Rubrerythrin - - - 0.0000000000000000000003502 101.0
HKD3_k127_5795203_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000001101 97.0
HKD3_k127_5795203_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000376 64.0
HKD3_k127_5817327_0 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000595 78.0
HKD3_k127_5818040_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 385.0
HKD3_k127_5818040_1 phosphoglucosamine mutase activity K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000005885 168.0
HKD3_k127_5826577_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 563.0
HKD3_k127_5826577_1 Type II/IV secretion system protein K02669 - - 0.000000006051 59.0
HKD3_k127_5837568_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 325.0
HKD3_k127_5837568_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002181 257.0
HKD3_k127_5837568_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000001214 241.0
HKD3_k127_5837568_3 (ABC) transporter K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000106 236.0
HKD3_k127_5846546_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 312.0
HKD3_k127_5846546_1 ABC-2 family transporter protein - - - 0.0000000000001025 82.0
HKD3_k127_5850622_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 257.0
HKD3_k127_5850622_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000626 218.0
HKD3_k127_5866052_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 375.0
HKD3_k127_5866052_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 307.0
HKD3_k127_5866052_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HKD3_k127_5866052_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000002014 223.0
HKD3_k127_5866052_4 type II secretion system K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.000000000000000004382 96.0
HKD3_k127_5895006_0 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000004727 251.0
HKD3_k127_5895006_1 Dihydroneopterin aldolase - - - 0.000000000000000000000000000000000000009357 153.0
HKD3_k127_5895006_2 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000002183 147.0
HKD3_k127_5895006_3 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000000005087 140.0
HKD3_k127_5895006_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000003727 110.0
HKD3_k127_5898291_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000002034 145.0
HKD3_k127_5898291_1 - - - - 0.0000000000000000000000001702 111.0
HKD3_k127_5898291_2 - - - - 0.0000000000000008029 79.0
HKD3_k127_5910165_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000002894 83.0
HKD3_k127_5911605_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 421.0
HKD3_k127_5911605_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000002271 143.0
HKD3_k127_5911605_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.000000000000000000000000001981 118.0
HKD3_k127_5923834_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 334.0
HKD3_k127_5923834_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000009679 155.0
HKD3_k127_5923834_2 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000001044 113.0
HKD3_k127_5923834_3 Protein of unknown function DUF72 - - - 0.00005869 48.0
HKD3_k127_5923834_4 Belongs to the glycosyl hydrolase 43 family - - - 0.00006195 55.0
HKD3_k127_5927301_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000007331 151.0
HKD3_k127_5927301_1 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000004131 121.0
HKD3_k127_5927301_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000003614 98.0
HKD3_k127_5927301_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000007822 96.0
HKD3_k127_5935224_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 607.0
HKD3_k127_5935224_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001433 260.0
HKD3_k127_5944071_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 374.0
HKD3_k127_5944071_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000001313 145.0
HKD3_k127_5979794_0 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000002719 159.0
HKD3_k127_5979794_1 Oxidoreductase - - - 0.00000000000000001452 90.0
HKD3_k127_598907_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 382.0
HKD3_k127_598907_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 369.0
HKD3_k127_598907_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 316.0
HKD3_k127_598907_3 - - - - 0.00000000000000000000000000000000000000000000003958 172.0
HKD3_k127_598907_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000001593 158.0
HKD3_k127_598907_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000005491 157.0
HKD3_k127_598907_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000001743 147.0
HKD3_k127_598907_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000002268 132.0
HKD3_k127_598907_8 RNA recognition motif - - - 0.0000000000000000000000006695 107.0
HKD3_k127_598907_9 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000008333 64.0
HKD3_k127_5991613_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002578 256.0
HKD3_k127_5991613_1 Prolyl oligopeptidase family - - - 0.00000001229 66.0
HKD3_k127_6005081_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
HKD3_k127_6005081_1 TPR repeat-containing protein - - - 0.00000002714 63.0
HKD3_k127_6011716_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001032 247.0
HKD3_k127_6011716_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000002504 248.0
HKD3_k127_6011716_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000004922 207.0
HKD3_k127_6011716_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase - - - 0.00000000000000000000000252 109.0
HKD3_k127_6024953_1 Domain of unknown function (DUF4838) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 403.0
HKD3_k127_6024953_2 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
HKD3_k127_6024953_3 - - - - 0.000000000000000000000000000000000000000000001711 181.0
HKD3_k127_6024953_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000002543 54.0
HKD3_k127_6039134_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
HKD3_k127_6039134_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 333.0
HKD3_k127_6039134_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003024 66.0
HKD3_k127_6039134_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 292.0
HKD3_k127_6039134_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
HKD3_k127_6039134_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007148 267.0
HKD3_k127_6039134_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000002947 196.0
HKD3_k127_6039134_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000001554 185.0
HKD3_k127_6039134_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000227 170.0
HKD3_k127_6039134_8 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001255 130.0
HKD3_k127_6039134_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000001993 109.0
HKD3_k127_6045397_0 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000002847 199.0
HKD3_k127_6045397_1 - - - - 0.000000000000000000000000000000638 124.0
HKD3_k127_6047333_0 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000004292 241.0
HKD3_k127_6047333_1 transposase activity - - - 0.000000000000008482 87.0
HKD3_k127_6048369_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 482.0
HKD3_k127_6048369_1 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000006264 230.0
HKD3_k127_6048369_2 polynucleotide 5'-hydroxyl-kinase activity K06947 - - 0.0000000000000000000000000000000000000000000000000000000000893 218.0
HKD3_k127_6048369_3 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000001346 177.0
HKD3_k127_6048369_4 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000003842 149.0
HKD3_k127_6048369_5 Sulfatase - - - 0.000000000000000000000000000005269 120.0
HKD3_k127_6048369_6 TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2 - - - 0.0000000000000001303 90.0
HKD3_k127_6067575_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
HKD3_k127_6067575_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000004995 176.0
HKD3_k127_6067575_2 beta-galactosidase activity - - - 0.000000000000000000000000000000000000002991 154.0
HKD3_k127_6067575_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000002058 115.0
HKD3_k127_6067575_4 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.0000000765 62.0
HKD3_k127_6085317_0 carbohydrate transport K02025,K02027,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 471.0
HKD3_k127_6085317_1 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000006514 191.0
HKD3_k127_6095785_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001132 278.0
HKD3_k127_610887_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 9.271e-199 635.0
HKD3_k127_610887_1 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000073 162.0
HKD3_k127_610887_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000001998 97.0
HKD3_k127_6126490_0 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004066 284.0
HKD3_k127_6126490_1 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000003531 190.0
HKD3_k127_6126490_2 - - - - 0.0000000000000000000000000000000000000000000002223 177.0
HKD3_k127_6139003_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 391.0
HKD3_k127_6139003_1 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
HKD3_k127_6139003_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000005161 141.0
HKD3_k127_6164689_0 arabinan catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 586.0
HKD3_k127_6164689_1 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 305.0
HKD3_k127_6164689_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
HKD3_k127_6164689_3 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 286.0
HKD3_k127_6164689_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000001165 207.0
HKD3_k127_6164689_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000005666 149.0
HKD3_k127_6164689_6 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000004256 66.0
HKD3_k127_6165063_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 455.0
HKD3_k127_6165063_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 332.0
HKD3_k127_6165426_0 Protein of unknown function (DUF1290) - - - 0.0000000000000000000000000000012 125.0
HKD3_k127_6165426_1 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000000000000003614 121.0
HKD3_k127_6165426_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000848 91.0
HKD3_k127_6169951_0 Abhydrolase family - - - 0.0000000000000000000000000000006883 136.0
HKD3_k127_6169951_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000003208 100.0
HKD3_k127_6169951_2 Domain of unknown function (DUF4091) - - - 0.000000000000001376 87.0
HKD3_k127_6172498_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
HKD3_k127_6172498_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000002315 199.0
HKD3_k127_6172498_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000005239 181.0
HKD3_k127_6172498_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002782 161.0
HKD3_k127_6172498_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000002177 85.0
HKD3_k127_6172498_5 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 0.000000000000006419 74.0
HKD3_k127_6172498_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000001522 72.0
HKD3_k127_6172498_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000001356 61.0
HKD3_k127_6178100_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 377.0
HKD3_k127_6178100_1 Penicillin-binding protein, transpeptidase domain protein K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 332.0
HKD3_k127_6178100_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000516 167.0
HKD3_k127_6178788_0 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K18330 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000004069 192.0
HKD3_k127_6178788_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000003727 164.0
HKD3_k127_6178788_2 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.00001286 48.0
HKD3_k127_6182131_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 386.0
HKD3_k127_6182131_1 CoA-transferase activity K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 372.0
HKD3_k127_6182131_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000002824 226.0
HKD3_k127_6182131_3 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000001105 170.0
HKD3_k127_6182131_4 CoA-transferase activity K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000008018 165.0
HKD3_k127_6187667_0 Family of unknown function (DUF5317) - - - 0.000000000000000008715 92.0
HKD3_k127_6187667_1 HD domain - - - 0.000000002514 68.0
HKD3_k127_6189070_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000005229 143.0
HKD3_k127_6189070_1 polysaccharide deacetylase - - - 0.00001227 57.0
HKD3_k127_6192526_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 343.0
HKD3_k127_6192526_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000004657 143.0
HKD3_k127_6192526_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000102 128.0
HKD3_k127_6192526_3 - - - - 0.0000000000000000000002648 101.0
HKD3_k127_6192526_4 FR47-like protein - - - 0.00000000000003269 84.0
HKD3_k127_6201202_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
HKD3_k127_6201202_1 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00001675 50.0
HKD3_k127_6212199_0 PFAM PKD domain containing protein - - - 0.00000004356 64.0
HKD3_k127_6214335_0 PFAM glycoside hydrolase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 470.0
HKD3_k127_6214335_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 303.0
HKD3_k127_6214335_2 - - - - 0.00002687 54.0
HKD3_k127_6232316_0 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000002639 229.0
HKD3_k127_6250829_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 522.0
HKD3_k127_6250829_1 Glucoamylase - - - 0.000005895 55.0
HKD3_k127_6254967_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000139 209.0
HKD3_k127_6254967_1 Cytochrome c - - - 0.00000000000000000000000000002569 118.0
HKD3_k127_6254967_2 - - - - 0.000737 48.0
HKD3_k127_6263046_0 PFAM chaperonin Cpn60 TCP-1 - - - 4.814e-208 659.0
HKD3_k127_6263046_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000000000000001602 148.0
HKD3_k127_6263046_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000002291 121.0
HKD3_k127_6263046_3 domain protein K20276 - - 0.0000007801 61.0
HKD3_k127_6277018_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000003261 220.0
HKD3_k127_6277018_1 carbohydrate binding K17495 - - 0.00000000001917 78.0
HKD3_k127_6277018_2 Endonuclease Exonuclease phosphatase - - - 0.000000003203 65.0
HKD3_k127_6283356_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.82e-297 935.0
HKD3_k127_6283356_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000001153 257.0
HKD3_k127_6283356_2 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.000000000000000000000000000000000003818 143.0
HKD3_k127_6283356_3 Type II IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000001504 135.0
HKD3_k127_6284213_0 Putative zinc-finger - - - 0.000005687 57.0
HKD3_k127_6288268_0 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 261.0
HKD3_k127_6288268_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000003463 203.0
HKD3_k127_6288268_2 NUDIX domain K03575 - - 0.000000000000000000000000000000000005059 140.0
HKD3_k127_6295303_0 Putative regulatory protein - - - 0.000000000000008807 78.0
HKD3_k127_6295303_1 domain protein K01342,K06894,K12287,K20276 - 3.4.21.62 0.00000000001896 75.0
HKD3_k127_6301279_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006478 292.0
HKD3_k127_6301279_1 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0000000000000000002291 92.0
HKD3_k127_6301279_2 Two component regulator propeller - - - 0.00000000000008485 84.0
HKD3_k127_6301279_3 Vault protein inter-alpha-trypsin domain - - - 0.0002555 55.0
HKD3_k127_6312604_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 341.0
HKD3_k127_6312604_1 nuclease activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 315.0
HKD3_k127_6312604_2 Sigma 54 modulation/S30EA ribosomal protein C terminus K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000825 186.0
HKD3_k127_6312604_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000002839 91.0
HKD3_k127_6355706_0 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 504.0
HKD3_k127_6355706_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000134 223.0
HKD3_k127_6355706_2 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000001398 186.0
HKD3_k127_6355706_3 general secretion pathway protein K02456,K02679 - - 0.000000000000000000000000000000000000001363 156.0
HKD3_k127_6355706_4 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000001055 65.0
HKD3_k127_63697_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 498.0
HKD3_k127_63697_2 beta-galactosidase activity - - - 0.00000000000000000001396 100.0
HKD3_k127_63697_3 - - - - 0.00003416 54.0
HKD3_k127_6373060_0 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000003691 215.0
HKD3_k127_6379674_0 oxidoreductase activity, acting on CH-OH group of donors K00068 - 1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 372.0
HKD3_k127_6379674_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000006579 54.0
HKD3_k127_6387043_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000001183 210.0
HKD3_k127_6387043_1 OsmC-like protein - - - 0.000000000000000000000005553 106.0
HKD3_k127_6387043_2 lipopolysaccharide transport K09774 - - 0.000000000000000005164 99.0
HKD3_k127_6387043_4 sequence-specific DNA binding - - - 0.00002197 50.0
HKD3_k127_6387259_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002057 261.0
HKD3_k127_6387259_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000006851 154.0
HKD3_k127_6387259_2 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000004542 109.0
HKD3_k127_6387504_0 cell adhesion K02650 - - 0.00000000000000000000000001703 112.0
HKD3_k127_6401735_0 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000001435 162.0
HKD3_k127_6401735_1 VanW like protein K18346 - - 0.0000000000000000000000000000000000003447 151.0
HKD3_k127_6401735_2 PFAM Cysteine-rich secretory protein family - - - 0.000000000000473 81.0
HKD3_k127_6414830_0 Protein of unknown function (DUF3866) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 340.0
HKD3_k127_6414830_1 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001184 270.0
HKD3_k127_6414830_2 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000008761 177.0
HKD3_k127_6414830_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000001124 141.0
HKD3_k127_6414830_4 membrane transporter protein K07090 - - 0.0000000000000000000001121 102.0
HKD3_k127_6423468_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 306.0
HKD3_k127_6423468_1 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000287 206.0
HKD3_k127_6423468_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000003641 179.0
HKD3_k127_6431493_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 377.0
HKD3_k127_6431493_1 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000001961 103.0
HKD3_k127_6442188_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000004548 113.0
HKD3_k127_6442188_1 amino acid aldolase or racemase - - - 0.0000000000000000000000005871 106.0
HKD3_k127_6442188_2 Heparinase K20525 - 4.2.2.26 0.000004082 60.0
HKD3_k127_6469527_0 Glycogen debranching enzyme - - - 2.509e-246 787.0
HKD3_k127_6469527_1 polygalacturonase activity K13735 - - 0.000000000000000006889 91.0
HKD3_k127_6471898_0 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001196 194.0
HKD3_k127_6471898_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000003914 190.0
HKD3_k127_6471898_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000008123 128.0
HKD3_k127_6487132_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
HKD3_k127_6487132_1 Putative neutral zinc metallopeptidase K06973 - - 0.0000000000000000000000000000339 119.0
HKD3_k127_6487132_2 Small Multidrug Resistance protein - - - 0.00000000000000000004592 94.0
HKD3_k127_6487132_3 Bacterial membrane protein, YfhO - - - 0.0000000000000000001405 91.0
HKD3_k127_6488658_0 Belongs to the glycosyl hydrolase 31 family - - - 1.818e-201 637.0
HKD3_k127_6506179_0 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 384.0
HKD3_k127_6506179_1 threonine synthase activity K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
HKD3_k127_6506179_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000001046 234.0
HKD3_k127_6509504_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 572.0
HKD3_k127_6509504_1 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000008445 235.0
HKD3_k127_6509504_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000003704 204.0
HKD3_k127_6509504_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000001655 67.0
HKD3_k127_6512817_0 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000008303 235.0
HKD3_k127_6515881_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 353.0
HKD3_k127_6538088_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 379.0
HKD3_k127_6538088_1 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 319.0
HKD3_k127_6538088_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008992 286.0
HKD3_k127_6538088_3 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000002107 243.0
HKD3_k127_6538088_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000004211 141.0
HKD3_k127_6538088_5 general secretion pathway protein K02456 - - 0.000000003119 66.0
HKD3_k127_6559617_0 Belongs to the CarB family K01955 - 6.3.5.5 7.022e-196 615.0
HKD3_k127_6559617_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 411.0
HKD3_k127_6559617_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 313.0
HKD3_k127_6559617_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 312.0
HKD3_k127_6559617_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000004029 224.0
HKD3_k127_6562626_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.425e-203 646.0
HKD3_k127_6562626_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 495.0
HKD3_k127_6562626_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000001743 214.0
HKD3_k127_6562626_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000003836 184.0
HKD3_k127_6562626_4 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.00000000000000000000000000000000001602 139.0
HKD3_k127_6562626_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000001066 100.0
HKD3_k127_6562626_6 GlcNAc-PI de-N-acetylase K01463 - - 0.0003438 43.0
HKD3_k127_6608592_0 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000495 268.0
HKD3_k127_6632501_0 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000004413 180.0
HKD3_k127_6632501_1 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000002086 164.0
HKD3_k127_6632501_2 S-layer homology domain - - - 0.0000000000000002392 95.0
HKD3_k127_6632501_3 - - - - 0.00000001153 59.0
HKD3_k127_6634796_0 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000371 137.0
HKD3_k127_6634796_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000007088 108.0
HKD3_k127_6634796_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000002597 93.0
HKD3_k127_6639537_0 ferredoxin oxidoreductase K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 316.0
HKD3_k127_6639537_1 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000003768 126.0
HKD3_k127_6639537_2 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.00000000000000000003041 93.0
HKD3_k127_6640521_0 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000001458 217.0
HKD3_k127_6640521_1 - - - - 0.00000000000000000000000004518 125.0
HKD3_k127_6659168_0 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD3_k127_6659168_1 - - - - 0.00000000000000000000000000000272 134.0
HKD3_k127_6659168_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000001864 89.0
HKD3_k127_6659168_3 Phosphodiester glycosidase - - - 0.0000000000006809 79.0
HKD3_k127_6659168_4 Acetyltransferase (GNAT) domain - - - 0.00000000002057 75.0
HKD3_k127_6659168_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000001268 70.0
HKD3_k127_6659168_6 Ribosomal protein S21 K02970 - - 0.000000001596 60.0
HKD3_k127_6659168_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0001242 44.0
HKD3_k127_6659497_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.548e-204 647.0
HKD3_k127_6659497_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000005705 191.0
HKD3_k127_6659497_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000009719 166.0
HKD3_k127_6660899_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000005974 175.0
HKD3_k127_6660899_1 Beta-galactosidase - - - 0.0000000009337 66.0
HKD3_k127_6667999_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD3_k127_6667999_1 Metallophosphoesterase K07098 - - 0.0000000000000000000001796 102.0
HKD3_k127_6671888_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 324.0
HKD3_k127_6671888_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000004433 104.0
HKD3_k127_6671888_2 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000294 55.0
HKD3_k127_6678470_0 Belongs to the glycosyl hydrolase 32 family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000008756 130.0
HKD3_k127_6678470_1 cobalamin catabolic process K13912,K19525 - - 0.00000000000000000000001515 119.0
HKD3_k127_667998_0 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 323.0
HKD3_k127_667998_1 depolymerase - - - 0.000000000001654 71.0
HKD3_k127_6723921_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 297.0
HKD3_k127_6723921_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000004141 179.0
HKD3_k127_6728758_0 Phosphotransferase system, EIIC K02761 - - 0.000000000000000000000000000000000000000000000000000000000000004909 225.0
HKD3_k127_6736595_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 367.0
HKD3_k127_6736595_1 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000616 199.0
HKD3_k127_6736595_2 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000008237 170.0
HKD3_k127_6736595_3 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000829 146.0
HKD3_k127_6736595_4 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002166 103.0
HKD3_k127_6736595_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000004469 69.0
HKD3_k127_6736595_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000004629 49.0
HKD3_k127_6739423_0 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 533.0
HKD3_k127_6739423_1 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.000000000000006868 86.0
HKD3_k127_6739423_2 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.00000002746 56.0
HKD3_k127_6739423_3 Belongs to the MtfA family K09933 - - 0.0008715 51.0
HKD3_k127_6756367_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000004316 58.0
HKD3_k127_6756367_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00002135 48.0
HKD3_k127_6760425_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000003502 95.0
HKD3_k127_6760425_1 Transfers the fatty acyl group on membrane lipoproteins K03820 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000003252 81.0
HKD3_k127_6780556_0 Kelch repeat-containing protein - - - 0.0000002506 61.0
HKD3_k127_6780556_1 Pectate lyase - - - 0.000008661 60.0
HKD3_k127_6780556_2 PFAM O-Antigen K07234 - - 0.0003825 52.0
HKD3_k127_6783539_0 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000002053 167.0
HKD3_k127_6783539_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000008014 151.0
HKD3_k127_6789353_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
HKD3_k127_6789353_1 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000000000000000001116 213.0
HKD3_k127_6789353_2 AsmA family K07289 - - 0.000169 55.0
HKD3_k127_679598_0 Oxidoreductase NAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 448.0
HKD3_k127_680106_0 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000009323 199.0
HKD3_k127_680106_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000001469 106.0
HKD3_k127_6805404_0 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000001298 186.0
HKD3_k127_6805404_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000006075 111.0
HKD3_k127_6809986_0 nucleotide-excision repair K03702,K08999 - - 5.338e-288 898.0
HKD3_k127_6809986_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003293 284.0
HKD3_k127_6811784_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 492.0
HKD3_k127_6811784_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 467.0
HKD3_k127_6811784_2 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004964 259.0
HKD3_k127_6811784_3 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009603 244.0
HKD3_k127_6811784_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000001075 216.0
HKD3_k127_6811784_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000004872 178.0
HKD3_k127_6811784_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000001737 156.0
HKD3_k127_6811784_7 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000001149 160.0
HKD3_k127_6811784_8 PFAM TadE family protein - - - 0.00000007721 63.0
HKD3_k127_6811784_9 general secretion pathway protein - - - 0.0001251 51.0
HKD3_k127_6825326_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 485.0
HKD3_k127_6825326_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007859 269.0
HKD3_k127_6825326_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000002673 187.0
HKD3_k127_6828383_0 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 357.0
HKD3_k127_6828383_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000001629 174.0
HKD3_k127_6831639_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 527.0
HKD3_k127_6831639_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001917 265.0
HKD3_k127_6831639_2 Periplasmic binding protein domain - - - 0.000000000000000007957 85.0
HKD3_k127_6835997_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000006552 212.0
HKD3_k127_6849330_0 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000001464 161.0
HKD3_k127_6849330_1 Fibronectin type III - - - 0.000000000437 74.0
HKD3_k127_6854066_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000002538 75.0
HKD3_k127_6854066_1 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.0000003226 65.0
HKD3_k127_6854066_2 PFAM metallophosphoesterase - - - 0.000008735 60.0
HKD3_k127_6855161_0 succinyl-diaminopimelate desuccinylase activity K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 404.0
HKD3_k127_6855161_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 348.0
HKD3_k127_685878_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 474.0
HKD3_k127_685878_1 Putative SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003554 224.0
HKD3_k127_6863028_0 glucan 1,4-alpha-glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 554.0
HKD3_k127_6863028_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 495.0
HKD3_k127_6863028_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 477.0
HKD3_k127_6863028_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 452.0
HKD3_k127_6863028_4 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 452.0
HKD3_k127_6863028_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000002443 190.0
HKD3_k127_6863028_6 COG NOG26804 non supervised orthologous group - - - 0.000000000000000000000000000001967 129.0
HKD3_k127_6873851_0 PFAM PKD domain containing protein - - - 0.0004474 52.0
HKD3_k127_6880563_0 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
HKD3_k127_6880563_1 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000008516 214.0
HKD3_k127_6880563_2 acid phosphatase activity - - - 0.00000000000000000000000000000000001486 154.0
HKD3_k127_6880563_3 PFAM glycoside hydrolase family 39 - - - 0.00001486 58.0
HKD3_k127_6932357_0 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 278.0
HKD3_k127_6932357_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000795 209.0
HKD3_k127_6932357_2 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000000000000000004975 95.0
HKD3_k127_6964705_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 327.0
HKD3_k127_6964705_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000001378 250.0
HKD3_k127_6980938_0 ribosylpyrimidine nucleosidase activity K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 322.0
HKD3_k127_6980938_1 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000002022 159.0
HKD3_k127_6984956_0 tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 378.0
HKD3_k127_6984956_1 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
HKD3_k127_6984956_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.000000000000000000000000000000003213 132.0
HKD3_k127_6984956_3 Multidrug transporter K08153 - - 0.00000000000001586 87.0
HKD3_k127_6995310_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000004333 203.0
HKD3_k127_6995310_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000004552 188.0
HKD3_k127_6995310_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.00000000000000000000000000001132 120.0
HKD3_k127_6995310_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000676 93.0
HKD3_k127_7012033_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 4.427e-219 689.0
HKD3_k127_7012033_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000008649 132.0
HKD3_k127_7012033_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000001942 68.0
HKD3_k127_7012033_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.0000000009091 61.0
HKD3_k127_7012033_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000004258 59.0
HKD3_k127_702752_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01219 - 3.2.1.81 0.0000000000000000000000000000169 128.0
HKD3_k127_703271_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 501.0
HKD3_k127_703271_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000001523 233.0
HKD3_k127_703271_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000002979 199.0
HKD3_k127_7034361_0 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 493.0
HKD3_k127_7034361_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000009258 223.0
HKD3_k127_7034361_2 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.0000000000000000000000000000000001458 145.0
HKD3_k127_7034361_3 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000009486 111.0
HKD3_k127_7067029_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 544.0
HKD3_k127_7067029_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 471.0
HKD3_k127_7067029_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 389.0
HKD3_k127_7067029_3 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
HKD3_k127_7074624_0 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000002344 190.0
HKD3_k127_7074624_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000002319 182.0
HKD3_k127_7074624_2 Glycosyltransferase Family 4 - - - 0.000002216 54.0
HKD3_k127_7074624_3 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.0005804 52.0
HKD3_k127_7080490_0 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
HKD3_k127_7101748_0 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000001059 168.0
HKD3_k127_7102662_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003419 256.0
HKD3_k127_7102662_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005238 248.0
HKD3_k127_7102662_2 membrane-associated protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000004509 106.0
HKD3_k127_7102662_3 PFAM Glycosyl transferase, group 1 K02844 - - 0.00000000000000000002818 100.0
HKD3_k127_7102662_4 Phospholipid methyltransferase - - - 0.00000000000000001028 94.0
HKD3_k127_7105329_0 domain protein K01342,K06894,K12287,K20276 - 3.4.21.62 0.000003313 60.0
HKD3_k127_7105329_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002109 54.0
HKD3_k127_7144789_0 HMGL-like K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 441.0
HKD3_k127_7144789_1 histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000001594 65.0
HKD3_k127_7197920_0 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000008154 197.0
HKD3_k127_7197920_1 HD domain - - - 0.00000000000000000000000000000000008948 137.0
HKD3_k127_7197920_2 Family of unknown function (DUF5317) - - - 0.000000000000000000000000003222 118.0
HKD3_k127_7197920_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000001689 93.0
HKD3_k127_7197920_4 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000001691 82.0
HKD3_k127_7198215_0 2-methylcitrate dehydratase activity - - - 0.000000000000000000000007085 111.0
HKD3_k127_7198215_1 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.0000000000007392 75.0
HKD3_k127_7212630_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000001073 191.0
HKD3_k127_7212630_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000007208 187.0
HKD3_k127_7212630_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000003054 84.0
HKD3_k127_721696_0 Belongs to the glycosyl hydrolase 32 family K01119 - 3.1.3.6,3.1.4.16 0.000000000000000000000000000000000000000001851 170.0
HKD3_k127_7221184_0 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 442.0
HKD3_k127_7221184_1 DnaB-like helicase N terminal domain K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 432.0
HKD3_k127_7221184_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000001097 209.0
HKD3_k127_7221184_3 bacterial-type flagellum organization - - - 0.00000000000000000000000000000000000000000000001386 180.0
HKD3_k127_7221184_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.0000000000000000000000000000000000000000484 170.0
HKD3_k127_7221184_5 Copper transport outer membrane protein, MctB - - - 0.00000000000000000000000000000000000001382 157.0
HKD3_k127_7221184_6 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001593 146.0
HKD3_k127_7221184_7 PFAM 4Fe-4S K00176 - 1.2.7.3 0.000000000000000000007799 95.0
HKD3_k127_7226694_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000002261 162.0
HKD3_k127_7226694_1 - - - - 0.000000000001275 75.0
HKD3_k127_7227938_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.406e-210 672.0
HKD3_k127_7227938_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000001219 186.0
HKD3_k127_7227938_2 - - - - 0.000000000000000000000000000000000002586 141.0
HKD3_k127_7227938_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000002548 112.0
HKD3_k127_7246474_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000004442 185.0
HKD3_k127_7291712_0 Sugar nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 354.0
HKD3_k127_7291712_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002058 129.0
HKD3_k127_7291712_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001435 130.0
HKD3_k127_7291712_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000008124 76.0
HKD3_k127_7312165_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 514.0
HKD3_k127_7312165_1 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 331.0
HKD3_k127_7318984_0 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.000000000000000000000000000000000000000000001792 175.0
HKD3_k127_7318984_1 Belongs to the D-glutamate cyclase family - - - 0.000000000000000002371 86.0
HKD3_k127_7321839_0 Glycogen debranching enzyme - - - 0.00000000000008556 84.0
HKD3_k127_7321839_1 beta-fructofuranosidase activity - - - 0.00000000000009817 75.0
HKD3_k127_7321839_2 - - - - 0.000000001697 61.0
HKD3_k127_7328196_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000008417 215.0
HKD3_k127_7328196_1 - - - - 0.000000004069 65.0
HKD3_k127_7336712_0 Protein of unknown function (DUF4127) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001257 297.0
HKD3_k127_7336712_1 Sigma-70 region 2 K03088 - - 0.000000000000000000001187 99.0
HKD3_k127_735738_0 DNA / pantothenate metabolism flavoprotein K21977 - 6.3.2.5 0.00000000000000000000000000000000000000000003578 170.0
HKD3_k127_735738_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000001186 75.0
HKD3_k127_7376611_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 598.0
HKD3_k127_7382353_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000006415 79.0
HKD3_k127_7382353_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001756 68.0
HKD3_k127_7382353_2 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000002804 64.0
HKD3_k127_7382353_3 COG COG1404 Subtilisin-like serine proteases Posttranslational modification protein turnover chaperones K08651 - 3.4.21.66 0.0003748 53.0
HKD3_k127_7392774_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 424.0
HKD3_k127_7392774_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000001368 166.0
HKD3_k127_7398461_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000006325 230.0
HKD3_k127_7398461_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000008031 224.0
HKD3_k127_7398461_2 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.000000000000000000000000000000000000000000006655 173.0
HKD3_k127_7398461_3 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000004708 104.0
HKD3_k127_7401250_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 426.0
HKD3_k127_7401250_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 382.0
HKD3_k127_7401250_2 beta-galactosidase activity K01190,K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 325.0
HKD3_k127_7401250_3 Protein of unknown function (DUF3465) - - - 0.000000000000000000000000000005096 127.0
HKD3_k127_7401250_4 NmrA family - - - 0.0000000000000000008226 89.0
HKD3_k127_7401250_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000001092 87.0
HKD3_k127_7401250_6 G-rich domain on putative tyrosine kinase - - - 0.000000003461 66.0
HKD3_k127_740974_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000002456 255.0
HKD3_k127_7409777_0 DNA topoisomerase type I activity K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 600.0
HKD3_k127_7443466_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 359.0
HKD3_k127_7443466_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000003051 179.0
HKD3_k127_7443466_2 Amidohydrolase family - - - 0.0000000000000002967 92.0
HKD3_k127_7460674_0 COG1082 Sugar phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
HKD3_k127_7460674_1 Trehalose utilisation - - - 0.000000000000000000000000000000000007816 147.0
HKD3_k127_7460674_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000003411 72.0
HKD3_k127_7469830_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 4.2.1.113,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000007986 256.0
HKD3_k127_7469830_1 Protein conserved in bacteria - - - 0.000000000000000000000000000001886 139.0
HKD3_k127_7469830_2 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.0000000003129 67.0
HKD3_k127_7469830_3 Copper binding proteins, plastocyanin/azurin family - - - 0.00000002256 67.0
HKD3_k127_7472179_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 348.0
HKD3_k127_7472179_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000001476 176.0
HKD3_k127_7472179_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000002309 104.0
HKD3_k127_7472179_3 PFAM Sporulation related domain - - - 0.00008184 52.0
HKD3_k127_7477978_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000103 241.0
HKD3_k127_7477978_1 hopanoid biosynthesis associated protein HpnK - - - 0.0000000000000000000000000000000000000000000000002425 196.0
HKD3_k127_7477978_2 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000005752 128.0
HKD3_k127_7477978_3 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000001443 123.0
HKD3_k127_7495940_0 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000005551 175.0
HKD3_k127_7502328_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 455.0
HKD3_k127_7517367_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 7.048e-236 744.0
HKD3_k127_7517367_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 519.0
HKD3_k127_7517367_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 339.0
HKD3_k127_7517367_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000001958 194.0
HKD3_k127_7517367_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000125 101.0
HKD3_k127_7533408_0 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000008141 184.0
HKD3_k127_7533408_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000001137 154.0
HKD3_k127_7536247_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000008712 131.0
HKD3_k127_7537964_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 458.0
HKD3_k127_7537964_1 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 409.0
HKD3_k127_7537964_2 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 312.0
HKD3_k127_7537964_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000002038 166.0
HKD3_k127_7537964_4 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000002992 113.0
HKD3_k127_7553148_0 TIGRFAM Phage - - - 0.0000000000000000000000000000004061 129.0
HKD3_k127_7553148_1 Protein of unknown function (DUF3489) - - - 0.0002677 46.0
HKD3_k127_7567053_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 444.0
HKD3_k127_7567053_1 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 362.0
HKD3_k127_7567053_2 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 287.0
HKD3_k127_7567053_3 Phosphoglycerate mutase family K02226,K15634 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000002179 157.0
HKD3_k127_7567053_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000004964 102.0
HKD3_k127_7567053_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000114 47.0
HKD3_k127_7567564_0 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 404.0
HKD3_k127_7567564_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000001299 231.0
HKD3_k127_7569778_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 5.494e-289 904.0
HKD3_k127_7569778_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
HKD3_k127_7569778_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000006537 215.0
HKD3_k127_7569778_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000001005 123.0
HKD3_k127_7590559_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 570.0
HKD3_k127_760877_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 612.0
HKD3_k127_7648517_0 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.00000000000000000000000000002081 135.0
HKD3_k127_7648517_1 oxidoreductase activity - - - 0.0000000000000000283 96.0
HKD3_k127_7649757_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.502e-219 700.0
HKD3_k127_7662805_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000003596 210.0
HKD3_k127_7662805_1 - - - - 0.00000004774 55.0
HKD3_k127_7664467_0 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 296.0
HKD3_k127_7664467_1 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000003409 98.0
HKD3_k127_7664467_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000001558 68.0
HKD3_k127_7669256_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 292.0
HKD3_k127_7697896_0 Sulfatase - - - 0.0000000000000000000000000000001615 129.0
HKD3_k127_7697896_1 HAF family - - - 0.00000005559 65.0
HKD3_k127_7697896_2 HAF family - - - 0.00008271 56.0
HKD3_k127_7718344_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 406.0
HKD3_k127_7718344_1 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 339.0
HKD3_k127_7718344_2 Peptidase M48 - - - 0.0000000000000000000000000000000007107 148.0
HKD3_k127_7718344_3 Negative regulator of sigma E activity K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.000001023 60.0
HKD3_k127_7730170_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000001191 194.0
HKD3_k127_7730170_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000005733 106.0
HKD3_k127_7730170_2 KWG Leptospira - - - 0.00003034 49.0
HKD3_k127_7734098_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 283.0
HKD3_k127_7734098_1 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000000008615 189.0
HKD3_k127_7734098_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000006414 86.0
HKD3_k127_7734842_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 394.0
HKD3_k127_7734842_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 381.0
HKD3_k127_7734842_2 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 329.0
HKD3_k127_7734842_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000001188 157.0
HKD3_k127_7734842_4 regulation of response to stimulus - - - 0.0000000000000000000000000000001939 130.0
HKD3_k127_7757120_0 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD3_k127_7757120_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000007306 80.0
HKD3_k127_7757910_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.726e-273 852.0
HKD3_k127_7757910_1 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 383.0
HKD3_k127_7757910_2 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000001096 130.0
HKD3_k127_7762526_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 4.042e-198 635.0
HKD3_k127_7762526_1 transferase activity, transferring glycosyl groups K16149,K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11,2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 383.0
HKD3_k127_7762526_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
HKD3_k127_7762526_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 269.0
HKD3_k127_7762526_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000001747 102.0
HKD3_k127_7762526_5 Protein of unknown function (DUF721) - - - 0.0000000000000005639 85.0
HKD3_k127_7772130_0 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000001736 166.0
HKD3_k127_777477_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 291.0
HKD3_k127_777477_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000001251 186.0
HKD3_k127_7789055_0 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004547 276.0
HKD3_k127_7789055_1 Biotin-lipoyl like K03543 - - 0.000000000002918 70.0
HKD3_k127_7794385_0 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000001536 118.0
HKD3_k127_7794385_1 zinc D-Ala-D-Ala carboxypeptidase activity K08641 - 3.4.13.22 0.0000000000003669 81.0
HKD3_k127_7794385_2 type II secretion system protein K02455 - - 0.00001332 55.0
HKD3_k127_7794385_3 Domain of unknown function (DUF5109) - - - 0.00003199 56.0
HKD3_k127_7801119_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 520.0
HKD3_k127_7801119_1 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 350.0
HKD3_k127_7801119_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 286.0
HKD3_k127_7801808_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 383.0
HKD3_k127_7801808_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000007707 111.0
HKD3_k127_780427_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009464 274.0
HKD3_k127_780427_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000002903 143.0
HKD3_k127_7847176_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000001398 237.0
HKD3_k127_7847176_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000002771 212.0
HKD3_k127_7847176_2 beta-galactosidase activity K01190,K01202,K12308 - 3.2.1.23,3.2.1.46 0.00000000000000000002941 101.0
HKD3_k127_7855608_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 460.0
HKD3_k127_7855608_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 427.0
HKD3_k127_7855608_2 TRANSCRIPTIONal - - - 0.00000000000000005309 83.0
HKD3_k127_7915700_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 562.0
HKD3_k127_7915700_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 383.0
HKD3_k127_7915700_2 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000006941 159.0
HKD3_k127_7915700_3 response regulator receiver K22010 - - 0.00008775 46.0
HKD3_k127_7918542_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 9.031e-303 953.0
HKD3_k127_7918542_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 407.0
HKD3_k127_7918542_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 343.0
HKD3_k127_7918542_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 302.0
HKD3_k127_7928807_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 9.824e-203 642.0
HKD3_k127_7928807_1 AMP binding - - - 0.00000000000001057 80.0
HKD3_k127_7928807_2 transcriptional regulator K07667 - - 0.000000000000421 70.0
HKD3_k127_7935453_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 348.0
HKD3_k127_7935453_1 polygalacturonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003167 267.0
HKD3_k127_7989679_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 282.0
HKD3_k127_7989679_1 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001018 277.0
HKD3_k127_7989679_2 depolymerase - - - 0.00000000000000004094 96.0
HKD3_k127_7989679_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00003818 53.0
HKD3_k127_8007382_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006952 278.0
HKD3_k127_801928_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 353.0
HKD3_k127_801928_1 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008234 281.0
HKD3_k127_801928_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000000000000000000000001705 176.0
HKD3_k127_8028035_0 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000002293 208.0
HKD3_k127_8028035_1 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000006845 203.0
HKD3_k127_8028035_2 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000002647 186.0
HKD3_k127_804163_0 organic acid phosphorylation K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 424.0
HKD3_k127_804163_1 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000324 147.0
HKD3_k127_804163_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000008192 69.0
HKD3_k127_804163_4 histidine kinase A domain protein - - - 0.00000007504 66.0
HKD3_k127_8050227_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000006951 221.0
HKD3_k127_8050227_1 amidohydrolase K07045 - - 0.00000000000000000000000000000002934 135.0
HKD3_k127_8050227_2 amidohydrolase K07045 - - 0.00000000000000000000000000002289 126.0
HKD3_k127_8050227_3 Parallel beta-helix repeats - - - 0.00000000000000000000000000007085 131.0
HKD3_k127_8050227_4 FlgD Ig-like domain K21449 - - 0.000000000000000000006967 106.0
HKD3_k127_8069438_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
HKD3_k127_8069438_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 376.0
HKD3_k127_8119276_0 Beta-galactosidase K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 418.0
HKD3_k127_8119276_1 unfolded protein binding K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007523 243.0
HKD3_k127_8119276_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000002999 177.0
HKD3_k127_8119276_3 - - - - 0.000000003057 67.0
HKD3_k127_8127290_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 8.186e-250 781.0
HKD3_k127_8127290_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 487.0
HKD3_k127_8127290_2 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000008457 203.0
HKD3_k127_8127290_3 23S rRNA-intervening sequence protein - - - 0.00000000000002105 75.0
HKD3_k127_8135427_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009013 300.0
HKD3_k127_8135427_1 Response regulator receiver - - - 0.00000000000000000000000000000000000002603 166.0
HKD3_k127_8139340_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 531.0
HKD3_k127_8139340_1 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
HKD3_k127_8139340_2 Stage V sporulation protein S (SpoVS) K06416 - - 0.00000000000000000000000000001255 121.0
HKD3_k127_8142117_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 395.0
HKD3_k127_8142117_1 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002693 191.0
HKD3_k127_8174555_0 Belongs to the sigma-70 factor family. ECF subfamily K03090 - - 0.0000000000000000000004438 101.0
HKD3_k127_8174555_1 Periplasmic protein TonB links inner and outer membranes - - - 0.00000001005 66.0
HKD3_k127_8183915_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 429.0
HKD3_k127_8183915_1 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.00001694 53.0
HKD3_k127_8196820_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000004985 101.0
HKD3_k127_8196820_1 general secretion pathway protein K02456,K02679 - - 0.000000000000000001559 97.0
HKD3_k127_8196820_2 Belongs to the peptidase S8 family K01342,K12287,K20276 - 3.4.21.62 0.00000000000002216 82.0
HKD3_k127_8196820_3 general secretion pathway protein K02456,K02650,K10926,K12285 - - 0.00000000003137 71.0
HKD3_k127_8211819_0 Diguanylate cyclase with GAF sensor - - - 0.000000000000000000000000000000000000000006238 165.0
HKD3_k127_8214510_0 Pectate lyase K01728 - 4.2.2.2 0.00000000000000000000000000000000000000000000000000000000000001929 228.0
HKD3_k127_8214510_1 Pectate lyase K01728 - 4.2.2.2 0.0000000000000000000000000000000000000000000000000848 183.0
HKD3_k127_8214510_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000006687 116.0
HKD3_k127_8214510_3 COG3119 Arylsulfatase A - - - 0.00000000001318 67.0
HKD3_k127_8221268_0 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000005572 124.0
HKD3_k127_8221268_1 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000001687 121.0
HKD3_k127_8221268_2 Fibronectin type III domain protein - - - 0.00004144 52.0
HKD3_k127_8228355_0 Sulfatase - - - 3.493e-221 699.0
HKD3_k127_8228355_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 472.0
HKD3_k127_8228355_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 329.0
HKD3_k127_8228355_3 COG COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000001463 128.0
HKD3_k127_8228610_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000009567 144.0
HKD3_k127_8228610_1 - - - - 0.00000000000009151 81.0
HKD3_k127_8236040_0 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
HKD3_k127_8236040_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000002084 205.0
HKD3_k127_8236040_2 protein kinase related protein - - - 0.0000000000000000000000000003063 130.0
HKD3_k127_8241302_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 475.0
HKD3_k127_8241302_1 leucyl-tRNA aminoacylation K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 443.0
HKD3_k127_8241302_2 Protein of unknown function (DUF3084) - - - 0.00000000000000001913 93.0
HKD3_k127_8245480_0 WG containing repeat - - - 0.00000000000000000000000000000000000000000000000000005887 195.0
HKD3_k127_8245480_1 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000008347 136.0
HKD3_k127_8260151_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 443.0
HKD3_k127_8260151_1 lyase activity - - - 0.0000000000000000000000000000005088 125.0
HKD3_k127_8274102_0 Cephalosporin hydroxylase - - - 0.000000000000000000000000000000000000000000000000000593 192.0
HKD3_k127_8274102_1 PFAM glycosyl hydrolase family 88 K15532 - 3.2.1.172 0.0000000000000000000000000000000000007713 153.0
HKD3_k127_8274102_2 - - - - 0.00000000000000000000000001533 113.0
HKD3_k127_8333094_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 397.0
HKD3_k127_8333094_1 - - - - 0.000000000000007388 81.0
HKD3_k127_8342778_0 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 327.0
HKD3_k127_8342778_1 PFAM SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001366 277.0
HKD3_k127_8342778_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000001708 199.0
HKD3_k127_834759_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 475.0
HKD3_k127_8348717_0 Belongs to the glycosyl hydrolase 32 family K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000006116 112.0
HKD3_k127_8349881_0 Required for flagellar hook formation. May act as a scaffolding protein K02389 GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044424,GO:0044444,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00006402 53.0
HKD3_k127_8367307_0 metallopeptidase activity K01179 - 3.2.1.4 0.000000000001128 78.0
HKD3_k127_8381824_0 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000009806 185.0
HKD3_k127_8381824_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000003434 183.0
HKD3_k127_8381824_2 Universal stress protein UspA - - - 0.00000000000000000000000000000000001982 145.0
HKD3_k127_8381824_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00001196 50.0
HKD3_k127_8386102_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000004747 199.0
HKD3_k127_8386102_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000001834 163.0
HKD3_k127_8386102_2 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000000000000405 123.0
HKD3_k127_8386102_3 Putative zinc-finger - - - 0.0001342 54.0
HKD3_k127_8449786_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 336.0
HKD3_k127_8449786_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 310.0
HKD3_k127_8449786_2 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000000001829 121.0
HKD3_k127_8450413_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000001197 197.0
HKD3_k127_8450413_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000001262 177.0
HKD3_k127_8450413_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000004197 100.0
HKD3_k127_8450413_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0002972 50.0
HKD3_k127_8455769_0 PFAM PKD domain containing protein - - - 0.0000000008807 69.0
HKD3_k127_8459175_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 8.788e-204 648.0
HKD3_k127_8459175_1 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 277.0
HKD3_k127_846388_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000002929 158.0
HKD3_k127_8472657_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 405.0
HKD3_k127_8472657_1 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
HKD3_k127_8472657_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000006769 165.0
HKD3_k127_8472657_3 Nitroreductase family - - - 0.0000000000000000000000000000000000003399 148.0
HKD3_k127_8472657_4 Phosphodiester glycosidase - - - 0.00000000000000000003917 103.0
HKD3_k127_8477591_0 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 319.0
HKD3_k127_8477591_1 Glycosyl-hydrolase family 116, catalytic region - - - 0.0000000000000000000000000000000000000000003258 167.0
HKD3_k127_8492797_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 288.0
HKD3_k127_8492797_1 bacteriocin transport K03561,K03562 - - 0.00000000000000000000000000000000005356 145.0
HKD3_k127_8492797_2 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000001163 129.0
HKD3_k127_8492797_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000003066 111.0
HKD3_k127_8492797_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000005381 83.0
HKD3_k127_8531133_0 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 253.0
HKD3_k127_8531133_1 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000005967 135.0
HKD3_k127_8531133_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000009909 117.0
HKD3_k127_8531133_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000101 86.0
HKD3_k127_8537822_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005556 224.0
HKD3_k127_8537822_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000003507 216.0
HKD3_k127_8537822_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000006728 190.0
HKD3_k127_8537822_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000001056 119.0
HKD3_k127_8537822_4 - - - - 0.00005907 49.0
HKD3_k127_8541758_0 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007693 285.0
HKD3_k127_8541758_1 glucosamine-6-phosphate deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000105 256.0
HKD3_k127_8543946_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005154 274.0
HKD3_k127_8543946_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000455 203.0
HKD3_k127_8558910_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 479.0
HKD3_k127_8558910_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 302.0
HKD3_k127_8558910_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001151 238.0
HKD3_k127_8558910_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000003783 177.0
HKD3_k127_8558910_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000001648 147.0
HKD3_k127_8568932_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 469.0
HKD3_k127_8568932_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000001841 129.0
HKD3_k127_8568932_2 PFAM Radical SAM - - - 0.000000000000000003866 85.0
HKD3_k127_8568932_3 type II secretion system protein G K02456 - - 0.0000000987 60.0
HKD3_k127_8608793_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 340.0
HKD3_k127_8608793_1 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
HKD3_k127_8608793_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000001578 115.0
HKD3_k127_8608793_3 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000007058 97.0
HKD3_k127_8619513_0 UvrD REP helicase K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 423.0
HKD3_k127_8619513_1 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000001747 101.0
HKD3_k127_8624545_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 517.0
HKD3_k127_8624545_1 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 241.0
HKD3_k127_8625159_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000106 159.0
HKD3_k127_8625159_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000001481 108.0
HKD3_k127_8636318_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 429.0
HKD3_k127_8636318_1 dehydrogenases and related proteins K22230 - - 0.000000000000000000000000000000000000000000000000000000003881 212.0
HKD3_k127_8636318_2 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.000000000000000000000000000001065 127.0
HKD3_k127_8636318_3 - - - - 0.00000000000000000000000001408 121.0
HKD3_k127_8636318_4 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000179 121.0
HKD3_k127_8636318_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000004652 110.0
HKD3_k127_8643463_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 422.0
HKD3_k127_8643463_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000002742 102.0
HKD3_k127_8643463_2 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000006317 70.0
HKD3_k127_8644352_0 FAD linked oxidase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 510.0
HKD3_k127_8644352_1 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000005675 205.0
HKD3_k127_8644352_2 4Fe-4S dicluster domain K00113,K11473 - 1.1.5.3 0.000003052 51.0
HKD3_k127_8675185_0 Carbohydrate family 9 binding domain-like - - - 0.000000000000000001986 100.0
HKD3_k127_8675185_1 beta-N-acetylhexosaminidase activity - - - 0.00005962 56.0
HKD3_k127_867781_0 Transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 492.0
HKD3_k127_8696314_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 624.0
HKD3_k127_8696314_1 acetyltransferase K00663 - 2.3.1.82 0.0000000000000000001714 94.0
HKD3_k127_8696314_2 interspecies interaction between organisms K18353 - - 0.0000000000000000002714 93.0
HKD3_k127_8732518_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 439.0
HKD3_k127_8732518_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 GO:0003674,GO:0003824,GO:0003852,GO:0003985,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046912,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.3.13 0.000000000000000000000000009349 110.0
HKD3_k127_8733615_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 490.0
HKD3_k127_8733615_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 454.0
HKD3_k127_8733615_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001398 123.0
HKD3_k127_8733615_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000001989 85.0
HKD3_k127_8744782_0 Domain of unknown function (DUF4838) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 464.0
HKD3_k127_8744782_1 BNR repeat-containing family member - - - 0.0000000000328 64.0
HKD3_k127_8748051_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000009245 225.0
HKD3_k127_8748051_1 carboxylic acid catabolic process - - - 0.000000000000000000305 89.0
HKD3_k127_8748819_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 2.255e-210 658.0
HKD3_k127_8748819_1 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000268 105.0
HKD3_k127_8757118_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000001081 169.0
HKD3_k127_8757118_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000002834 113.0
HKD3_k127_8764271_0 Alpha-L-fucosidase - - - 0.000000000000000000000000000000001557 143.0
HKD3_k127_8764271_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000846 56.0
HKD3_k127_8764271_2 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000878 56.0
HKD3_k127_8774796_0 Interferon-induced transmembrane protein - - - 0.00000000000000000000000008463 111.0
HKD3_k127_8774796_1 response to antibiotic - - - 0.000000000000000000009888 96.0
HKD3_k127_8774796_2 Domain of unknown function (DUF4190) - - - 0.000000002825 65.0
HKD3_k127_8774796_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000005924 63.0
HKD3_k127_8774796_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000002392 58.0
HKD3_k127_8782043_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000007477 147.0
HKD3_k127_8782043_1 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000007649 121.0
HKD3_k127_8782043_2 PFAM Bacterial protein of - - - 0.00000000000000226 78.0
HKD3_k127_8786936_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 427.0
HKD3_k127_8786936_1 outer membrane efflux protein K03287 - - 0.000004022 58.0
HKD3_k127_8798445_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 370.0
HKD3_k127_8798445_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 287.0
HKD3_k127_8798445_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000004591 221.0
HKD3_k127_8798445_3 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000007422 208.0
HKD3_k127_8798445_4 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000777 194.0
HKD3_k127_8798445_5 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000007427 173.0
HKD3_k127_8798445_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000006329 173.0
HKD3_k127_8798445_7 G5 domain protein - - - 0.00000000000000000000000000000000000000000134 166.0
HKD3_k127_8798445_8 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000598 108.0
HKD3_k127_8798445_9 ResB protein required for cytochrome c biosynthesis K07399 - - 0.0000000000000000000001107 113.0
HKD3_k127_8828653_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 384.0
HKD3_k127_8828653_1 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
HKD3_k127_8828653_2 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000003611 169.0
HKD3_k127_8828653_3 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000001478 159.0
HKD3_k127_8828653_4 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000001617 122.0
HKD3_k127_8828653_5 chaperone-mediated protein folding - - - 0.000000000000000000000000000003262 135.0
HKD3_k127_8828653_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000004165 109.0
HKD3_k127_8828653_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000002298 88.0
HKD3_k127_8841147_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 388.0
HKD3_k127_886684_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000521 111.0
HKD3_k127_886684_1 Tetratricopeptide repeat - - - 0.0001422 53.0
HKD3_k127_886684_2 arylsulfatase activity K07014 - - 0.0006186 51.0
HKD3_k127_8871472_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000001429 192.0
HKD3_k127_8885932_0 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 362.0
HKD3_k127_8885932_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000002591 153.0
HKD3_k127_8885932_2 Acetyltransferase (GNAT) domain - - - 0.00000000000005045 77.0
HKD3_k127_8900268_0 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 361.0
HKD3_k127_8900268_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000845 219.0
HKD3_k127_8900268_2 NifU-like N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
HKD3_k127_8900268_3 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000002478 192.0
HKD3_k127_8900268_4 Periplasmic binding protein K02016 - - 0.0000000000000000000208 94.0
HKD3_k127_8924561_0 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000006116 91.0
HKD3_k127_8934960_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 411.0
HKD3_k127_8934960_1 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 371.0
HKD3_k127_8934960_2 amidohydrolase K07045 - - 0.000000000000000000000004786 111.0
HKD3_k127_8943799_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000001396 124.0
HKD3_k127_8943799_1 PFAM glycoside hydrolase family 2 sugar binding - - - 0.000000000006971 75.0
HKD3_k127_8968223_0 von Willebrand factor, type A - - - 0.00000000000001166 83.0
HKD3_k127_8968223_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000009277 68.0
HKD3_k127_8974933_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 2.746e-194 621.0
HKD3_k127_8974933_1 Belongs to the D-glutamate cyclase family - - - 0.0000000000000000000000004071 105.0
HKD3_k127_8974933_2 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.00000000005502 68.0
HKD3_k127_8983975_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.482e-256 809.0
HKD3_k127_8983975_1 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000001575 141.0
HKD3_k127_89859_0 SPFH domain / Band 7 family - - - 5.247e-224 711.0
HKD3_k127_89859_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 524.0
HKD3_k127_8990519_0 PFAM formate C-acetyltransferase glycine radical K00656,K20038 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016829,GO:0016840,GO:0019695,GO:0033265,GO:0034641,GO:0042133,GO:0042135,GO:0042165,GO:0042402,GO:0042426,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044248,GO:0046983,GO:0065007,GO:0065008,GO:0070405,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 2.3.1.54,4.3.99.4 0.0000000000000000000000000000000000000001108 161.0
HKD3_k127_8997576_0 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000001455 239.0
HKD3_k127_8997576_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.0000000000000000000000000000000000000000000000002531 188.0
HKD3_k127_900464_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000007637 183.0
HKD3_k127_900464_1 PFAM glycoside hydrolase family 10 K01181 - 3.2.1.8 0.0001757 51.0
HKD3_k127_9027908_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000009815 240.0
HKD3_k127_9027908_1 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000002084 131.0
HKD3_k127_9027908_2 - - - - 0.000001301 51.0
HKD3_k127_9027908_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000005843 59.0
HKD3_k127_9041178_0 domain protein K12132,K20276 - 2.7.11.1 0.00000000000000000000000000000000000006611 160.0
HKD3_k127_9075140_0 PFAM Glycoside hydrolase, family 38 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 366.0
HKD3_k127_9090307_0 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 413.0
HKD3_k127_9090307_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006824 259.0
HKD3_k127_9090307_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000005152 77.0
HKD3_k127_9094908_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000004166 185.0
HKD3_k127_9094908_1 myo-inosose-2 dehydratase activity K03079 - 5.1.3.22 0.0000000000001722 70.0
HKD3_k127_9094908_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000004604 81.0
HKD3_k127_9104658_0 Pectate lyase - - - 0.000000000000000000000000000000000000000003503 159.0
HKD3_k127_9142618_0 Alpha-2-Macroglobulin K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 461.0
HKD3_k127_9161368_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 320.0
HKD3_k127_9161368_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000007278 165.0
HKD3_k127_9161368_2 Glutathione S-transferase - - - 0.00000003464 67.0
HKD3_k127_9173963_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 464.0
HKD3_k127_9173963_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 338.0
HKD3_k127_9173963_3 - - - - 0.0000000004605 66.0
HKD3_k127_9173963_4 Glycosyl hydrolase, family 20, catalytic domain - - - 0.0007303 48.0
HKD3_k127_9230396_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 457.0
HKD3_k127_9230396_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000001098 156.0
HKD3_k127_9249095_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 448.0
HKD3_k127_9249095_1 phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 323.0
HKD3_k127_9257814_0 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009043 331.0
HKD3_k127_9257814_1 PFAM KWG Leptospira - - - 0.00000000000000000000000000000000000000000000000000000000000000002129 235.0
HKD3_k127_9257814_2 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000001071 60.0
HKD3_k127_9292488_0 Iron-sulfur cluster-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008791 280.0
HKD3_k127_9321881_0 Crystallin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 351.0
HKD3_k127_9321881_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000001327 87.0
HKD3_k127_9323909_0 hydrolase activity, acting on glycosyl bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 368.0
HKD3_k127_9323909_1 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000006539 224.0
HKD3_k127_9324200_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.548e-199 634.0
HKD3_k127_9324200_1 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 352.0
HKD3_k127_9326309_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 555.0
HKD3_k127_9347489_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 9.744e-197 627.0
HKD3_k127_9347489_1 PFAM Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 366.0
HKD3_k127_9359148_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000003482 240.0
HKD3_k127_9359148_1 domain, Protein K20276 - - 0.0000000000000000004657 99.0
HKD3_k127_9359148_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00006424 50.0
HKD3_k127_9372821_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000001484 104.0
HKD3_k127_9372821_1 trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000005943 83.0
HKD3_k127_9379709_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 290.0
HKD3_k127_9379709_1 Polysaccharide pyruvyl transferase, CsaB - - - 0.00000000000000000000000000000000000000000000000002804 194.0
HKD3_k127_9379709_2 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000001347 112.0
HKD3_k127_9379709_3 Required for transformation and DNA binding K02245,K02456 GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000009071 86.0
HKD3_k127_9382696_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 314.0
HKD3_k127_9382696_1 - - - - 0.00000000000000000002745 102.0
HKD3_k127_9382696_3 DNA-templated transcription, initiation K03088 - - 0.000009353 48.0
HKD3_k127_9383270_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 445.0
HKD3_k127_9383270_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 287.0
HKD3_k127_9383270_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000004757 213.0
HKD3_k127_9383270_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0005125 48.0
HKD3_k127_942920_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005478 268.0
HKD3_k127_942920_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000009568 130.0
HKD3_k127_942920_2 Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000002788 121.0
HKD3_k127_942920_3 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000001193 125.0
HKD3_k127_9439591_0 PFAM glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000001081 230.0
HKD3_k127_9439591_1 arylsulfatase activity - - - 0.000000000000000000000000000001797 129.0
HKD3_k127_9447788_0 glucan 1,4-alpha-glucosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 317.0
HKD3_k127_9447788_1 DIM6 NTAB family - - - 0.000000000000000000000000000000000003257 145.0
HKD3_k127_9447788_2 Glycosyl hydrolase-like 10 - - - 0.0000000000000000003172 102.0
HKD3_k127_9457553_0 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000001146 100.0
HKD3_k127_9457553_1 lipopolysaccharide transport K04744 - - 0.00000000000002053 83.0
HKD3_k127_9488554_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000648 240.0
HKD3_k127_9488554_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000001863 187.0
HKD3_k127_9520970_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 284.0
HKD3_k127_9520970_1 - - - - 0.0000000000000000003026 93.0
HKD3_k127_9520970_2 Alpha-L-fucosidase - - - 0.00000000000000001447 95.0
HKD3_k127_9546624_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 309.0
HKD3_k127_9546624_1 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
HKD3_k127_9550133_0 Alcohol dehydrogenase GroES-like domain K00004,K00060 - 1.1.1.103,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 346.0
HKD3_k127_9550133_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000004523 126.0
HKD3_k127_9550133_2 Belongs to the glycosyl hydrolase 32 family - - - 0.0000000000000000000000000001927 131.0
HKD3_k127_9550133_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0003809 52.0
HKD3_k127_9570443_0 TIGRFAM TIGR00375 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 458.0
HKD3_k127_9570443_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000003405 196.0
HKD3_k127_9570443_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000002627 174.0
HKD3_k127_9570443_3 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000000000000312 142.0
HKD3_k127_9607572_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022 - - 0.00000000000000000000000000003905 126.0
HKD3_k127_9607572_1 recombinase activity - - - 0.000000009335 58.0
HKD3_k127_9622861_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 387.0
HKD3_k127_9622861_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007614 274.0
HKD3_k127_9622861_2 Domain of unknown function (DUF5011) - - - 0.00000000000001511 89.0
HKD3_k127_9622861_3 heme-binding sites - - - 0.0000000001325 76.0
HKD3_k127_993671_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000002266 200.0
HKD3_k127_993671_1 polygalacturonase activity K13735 - - 0.0000000000000000000000000000000000000000000004432 192.0
HKD3_k127_993671_2 Pfam:DUF1628 - - - 0.00000000001572 79.0