Overview

ID MAG01844
Name HKD3_bin.27
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family Xanthomonadaceae
Genus Arenimonas
Species
Assembly information
Completeness (%) 76.06
Contamination (%) 0.33
GC content (%) 69.0
N50 (bp) 29,276
Genome size (bp) 2,197,098

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2054

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1203505_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1801.0
HKD3_k127_1203505_1 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 607.0
HKD3_k127_1203505_10 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000004941 243.0
HKD3_k127_1203505_11 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000004911 234.0
HKD3_k127_1203505_12 regulator - - - 0.00000000000000000000000000000000000000000000000001896 191.0
HKD3_k127_1203505_13 PFAM short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000191 164.0
HKD3_k127_1203505_14 - - - - 0.00000000000000000000000000000000000000002637 159.0
HKD3_k127_1203505_15 - - - - 0.000000000000000000000000000000003708 131.0
HKD3_k127_1203505_16 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000192 120.0
HKD3_k127_1203505_17 Protein of unknown function (DUF3313) - - - 0.00000000000000000004092 101.0
HKD3_k127_1203505_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 499.0
HKD3_k127_1203505_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 335.0
HKD3_k127_1203505_4 Belongs to the LOG family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 330.0
HKD3_k127_1203505_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 301.0
HKD3_k127_1203505_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 294.0
HKD3_k127_1203505_7 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
HKD3_k127_1203505_8 Diguanylate cyclase K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002832 276.0
HKD3_k127_1203505_9 Ankyrin repeat K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
HKD3_k127_1251831_0 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.0 1437.0
HKD3_k127_1251831_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.77e-261 810.0
HKD3_k127_1251831_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 533.0
HKD3_k127_1251831_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 501.0
HKD3_k127_1251831_4 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 404.0
HKD3_k127_1251831_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000003622 173.0
HKD3_k127_1273320_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 6.209e-197 619.0
HKD3_k127_1273320_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 509.0
HKD3_k127_1273320_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 477.0
HKD3_k127_1273320_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 444.0
HKD3_k127_1273320_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 433.0
HKD3_k127_1273320_5 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 395.0
HKD3_k127_1273320_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 314.0
HKD3_k127_1273320_7 transcriptional regulator K06995 - - 0.000000000000000000000000000000000000000000001745 168.0
HKD3_k127_1273320_8 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000001722 70.0
HKD3_k127_1278169_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0 1198.0
HKD3_k127_1278169_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0 1002.0
HKD3_k127_1278169_2 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 9.57e-205 642.0
HKD3_k127_1278169_3 Type II secretion system protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 386.0
HKD3_k127_1278169_4 General secretion pathway protein K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002074 285.0
HKD3_k127_1278169_5 General secretion pathway protein K02459 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 281.0
HKD3_k127_1278169_6 General secretion pathway protein K02457 - - 0.00000000000000000000000000000000000000000000000000000000009073 209.0
HKD3_k127_1278169_7 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000000000000000000000000154 154.0
HKD3_k127_1278169_8 General secretion pathway protein K02456 - - 0.000000000000000000000000000000000000009922 159.0
HKD3_k127_127857_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.622e-242 757.0
HKD3_k127_127857_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 8.204e-207 645.0
HKD3_k127_127857_10 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007252 295.0
HKD3_k127_127857_11 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003608 249.0
HKD3_k127_127857_12 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002065 249.0
HKD3_k127_127857_13 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000007714 253.0
HKD3_k127_127857_14 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000004847 227.0
HKD3_k127_127857_15 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000001072 235.0
HKD3_k127_127857_16 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000001236 140.0
HKD3_k127_127857_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000819 94.0
HKD3_k127_127857_2 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 578.0
HKD3_k127_127857_3 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 530.0
HKD3_k127_127857_4 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 527.0
HKD3_k127_127857_5 abc transporter atp-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 439.0
HKD3_k127_127857_6 protein conserved in bacteria K09938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 458.0
HKD3_k127_127857_7 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 389.0
HKD3_k127_127857_8 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 321.0
HKD3_k127_127857_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 294.0
HKD3_k127_1278844_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.0 1267.0
HKD3_k127_1278844_1 Glycoprotease family K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 370.0
HKD3_k127_1278844_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 360.0
HKD3_k127_1278844_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 306.0
HKD3_k127_1291952_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0 1013.0
HKD3_k127_1291952_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 8.483e-288 895.0
HKD3_k127_1291952_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 2.163e-225 706.0
HKD3_k127_1291952_3 Intracellular protease K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 353.0
HKD3_k127_1291952_4 Sugar ABC transporter ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 323.0
HKD3_k127_1291952_5 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000000000001719 187.0
HKD3_k127_1303555_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 2090.0
HKD3_k127_1303555_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0 1211.0
HKD3_k127_1303555_10 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 543.0
HKD3_k127_1303555_11 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 526.0
HKD3_k127_1303555_12 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 521.0
HKD3_k127_1303555_13 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 516.0
HKD3_k127_1303555_14 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 502.0
HKD3_k127_1303555_15 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 516.0
HKD3_k127_1303555_16 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 493.0
HKD3_k127_1303555_17 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 488.0
HKD3_k127_1303555_18 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 479.0
HKD3_k127_1303555_19 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 463.0
HKD3_k127_1303555_2 PAS fold - - - 4.442e-293 923.0
HKD3_k127_1303555_20 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 438.0
HKD3_k127_1303555_21 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 396.0
HKD3_k127_1303555_22 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 368.0
HKD3_k127_1303555_23 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 356.0
HKD3_k127_1303555_24 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 348.0
HKD3_k127_1303555_25 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 333.0
HKD3_k127_1303555_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
HKD3_k127_1303555_27 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 313.0
HKD3_k127_1303555_28 Amino-transferase class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 315.0
HKD3_k127_1303555_29 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 294.0
HKD3_k127_1303555_3 Carboxypeptidase - - - 2.531e-269 835.0
HKD3_k127_1303555_30 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
HKD3_k127_1303555_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
HKD3_k127_1303555_32 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001572 278.0
HKD3_k127_1303555_33 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004324 269.0
HKD3_k127_1303555_34 Acyl-CoA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 261.0
HKD3_k127_1303555_35 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009766 237.0
HKD3_k127_1303555_36 ACR protein K07040 - - 0.000000000000000000000000000000000000000000000000000000000000002567 221.0
HKD3_k127_1303555_37 Pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
HKD3_k127_1303555_38 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
HKD3_k127_1303555_39 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000002899 214.0
HKD3_k127_1303555_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.291e-240 750.0
HKD3_k127_1303555_40 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000003191 203.0
HKD3_k127_1303555_41 - - - - 0.000000000000000000000000000000000000000000002208 171.0
HKD3_k127_1303555_42 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000000001118 158.0
HKD3_k127_1303555_43 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000007561 146.0
HKD3_k127_1303555_45 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000001035 118.0
HKD3_k127_1303555_47 response regulator K07663 - - 0.00000004716 54.0
HKD3_k127_1303555_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.987e-222 707.0
HKD3_k127_1303555_6 component I K01657 - 4.1.3.27 3.474e-220 694.0
HKD3_k127_1303555_7 chitinase K01183 - 3.2.1.14 6.176e-210 664.0
HKD3_k127_1303555_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 580.0
HKD3_k127_1303555_9 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 546.0
HKD3_k127_1385494_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1153.0
HKD3_k127_1385494_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1048.0
HKD3_k127_1385494_10 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 532.0
HKD3_k127_1385494_11 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 531.0
HKD3_k127_1385494_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 497.0
HKD3_k127_1385494_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 501.0
HKD3_k127_1385494_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 441.0
HKD3_k127_1385494_15 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 441.0
HKD3_k127_1385494_16 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 410.0
HKD3_k127_1385494_17 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 376.0
HKD3_k127_1385494_18 Biopolymer K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 366.0
HKD3_k127_1385494_19 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 316.0
HKD3_k127_1385494_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0 1002.0
HKD3_k127_1385494_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 323.0
HKD3_k127_1385494_21 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 303.0
HKD3_k127_1385494_22 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000005583 233.0
HKD3_k127_1385494_23 Biopolymer K03559 - - 0.000000000000000000000000000000000000000000000000000002735 200.0
HKD3_k127_1385494_24 succinate dehydrogenase K00242 - - 0.0000000000000000000000000000000000000000000000001662 188.0
HKD3_k127_1385494_25 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000000000000000008747 154.0
HKD3_k127_1385494_26 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000000004456 152.0
HKD3_k127_1385494_27 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000001968 147.0
HKD3_k127_1385494_28 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000005115 149.0
HKD3_k127_1385494_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.5e-323 1006.0
HKD3_k127_1385494_30 Sulfatase K01130 - 3.1.6.1 0.000000000000000001146 91.0
HKD3_k127_1385494_31 Protein of unknown function (DUF1674) - - - 0.000000000000007338 75.0
HKD3_k127_1385494_32 - - - - 0.000000000003122 79.0
HKD3_k127_1385494_34 PFAM Carbohydrate-selective porin OprB K07267 - - 0.000004886 48.0
HKD3_k127_1385494_4 Belongs to the glutamate synthase family - - - 1.939e-297 919.0
HKD3_k127_1385494_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.57e-282 872.0
HKD3_k127_1385494_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 2.513e-251 794.0
HKD3_k127_1385494_7 Nhl repeat - - - 1.986e-226 709.0
HKD3_k127_1385494_8 Lipoprotein releasing system transmembrane protein K09808 - - 2.373e-205 645.0
HKD3_k127_1385494_9 TRAP-type C4-dicarboxylate transport system, large permease component - - - 2.82e-198 631.0
HKD3_k127_1418891_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1255.0
HKD3_k127_1418891_1 Response regulator receiver - - - 0.0 1209.0
HKD3_k127_1418891_10 Belongs to the GARS family K01945 - 6.3.4.13 3.297e-226 707.0
HKD3_k127_1418891_11 Divalent cation transporter - - - 2.394e-201 632.0
HKD3_k127_1418891_12 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 527.0
HKD3_k127_1418891_13 Membrane protein required for beta-lactamase induction K03807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 518.0
HKD3_k127_1418891_14 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 520.0
HKD3_k127_1418891_15 Bacterial signalling protein N terminal repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 514.0
HKD3_k127_1418891_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 494.0
HKD3_k127_1418891_17 nadh pyrophosphatase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 462.0
HKD3_k127_1418891_18 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 456.0
HKD3_k127_1418891_19 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 357.0
HKD3_k127_1418891_2 His Kinase A (phosphoacceptor) domain - - - 0.0 1088.0
HKD3_k127_1418891_20 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
HKD3_k127_1418891_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 360.0
HKD3_k127_1418891_22 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
HKD3_k127_1418891_23 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000542 261.0
HKD3_k127_1418891_24 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 263.0
HKD3_k127_1418891_25 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000984 245.0
HKD3_k127_1418891_26 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
HKD3_k127_1418891_27 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000001874 247.0
HKD3_k127_1418891_28 type iii restriction K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000000003658 214.0
HKD3_k127_1418891_29 cell shape determination - - - 0.000000000000000000000000000000000000000000000000000000000000333 215.0
HKD3_k127_1418891_3 Thiol disulfide Interchange Protein K04084 - 1.8.1.8 4.4e-323 1017.0
HKD3_k127_1418891_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000009831 194.0
HKD3_k127_1418891_31 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000005898 180.0
HKD3_k127_1418891_32 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000000000000000000000004194 159.0
HKD3_k127_1418891_33 Acetyltransferase (GNAT) K06977 - - 0.0000000000000000000000000000000000000001807 156.0
HKD3_k127_1418891_34 Interferon-induced transmembrane protein - - - 0.000000000000000000000000000000000000002957 149.0
HKD3_k127_1418891_35 Protein of unknown function (DUF2752) - - - 0.00000000000000000000000000000000000004226 150.0
HKD3_k127_1418891_36 - - - - 0.00000000000000000000000000000000334 141.0
HKD3_k127_1418891_37 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000000000000000000004061 125.0
HKD3_k127_1418891_39 bacterial-type flagellum organization K02279,K02386 - - 0.000001181 53.0
HKD3_k127_1418891_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.165e-318 985.0
HKD3_k127_1418891_5 Acyltransferase - - - 2.928e-313 969.0
HKD3_k127_1418891_6 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 5.25e-291 894.0
HKD3_k127_1418891_7 Sulfatase - - - 2.992e-288 895.0
HKD3_k127_1418891_8 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.22e-286 893.0
HKD3_k127_1418891_9 Adenylate cyclase - - - 7.663e-269 843.0
HKD3_k127_1599347_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1482.0
HKD3_k127_1599347_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1105.0
HKD3_k127_1599347_10 peptidoglycan-binding protein, lysm - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 464.0
HKD3_k127_1599347_11 Signal transduction histidine kinase, glucose-6-phosphate specific K07675,K20263 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 463.0
HKD3_k127_1599347_12 Tropinone reductase K08081 - 1.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 445.0
HKD3_k127_1599347_13 Protein of unknown function (DUF3667) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 379.0
HKD3_k127_1599347_14 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 382.0
HKD3_k127_1599347_15 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 353.0
HKD3_k127_1599347_16 Stealth protein CR1, conserved region 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 335.0
HKD3_k127_1599347_17 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 312.0
HKD3_k127_1599347_18 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 307.0
HKD3_k127_1599347_19 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005572 253.0
HKD3_k127_1599347_2 signal peptide peptidase K04773 - - 0.0 1019.0
HKD3_k127_1599347_20 helix_turn_helix, Lux Regulon K20264 - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
HKD3_k127_1599347_21 - - - - 0.00000000000000000000000000000000000000000000000000000000007773 215.0
HKD3_k127_1599347_22 - - - - 0.0000000000000000000000000000000000000000000000000000001883 208.0
HKD3_k127_1599347_23 Protein of unknown function (DUF3106) - - - 0.00000000000000000000000000000000000000000001058 176.0
HKD3_k127_1599347_24 Domain of unknown function (DUF4286) - - - 0.0000000000000000000000001338 122.0
HKD3_k127_1599347_26 similarity to GP 17427840 K07497 - - 0.0000197 50.0
HKD3_k127_1599347_3 Amidohydrolase family - - - 1.328e-306 949.0
HKD3_k127_1599347_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 6.552e-246 769.0
HKD3_k127_1599347_5 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 1.43e-210 662.0
HKD3_k127_1599347_6 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 1.767e-199 646.0
HKD3_k127_1599347_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 608.0
HKD3_k127_1599347_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 506.0
HKD3_k127_1599347_9 DNA processing protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 492.0
HKD3_k127_1628603_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1125.0
HKD3_k127_1628603_1 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0 1093.0
HKD3_k127_1628603_10 Transposase - - - 0.0000000000000000000000000000000000000000003734 157.0
HKD3_k127_1628603_11 protein conserved in bacteria K09806 - - 0.0000000000000000000000000000000000003008 147.0
HKD3_k127_1628603_13 Protein of unknown function (DUF805) - - - 0.000000001551 65.0
HKD3_k127_1628603_2 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 584.0
HKD3_k127_1628603_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 546.0
HKD3_k127_1628603_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 458.0
HKD3_k127_1628603_5 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 332.0
HKD3_k127_1628603_6 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 289.0
HKD3_k127_1628603_7 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000001568 230.0
HKD3_k127_1628603_8 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000007094 208.0
HKD3_k127_1628603_9 Cell division protein - - - 0.0000000000000000000000000000000000000000000000000000000001561 230.0
HKD3_k127_1662815_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.499e-287 887.0
HKD3_k127_1662815_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 2.585e-225 714.0
HKD3_k127_1662815_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 607.0
HKD3_k127_1662815_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 503.0
HKD3_k127_1662815_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 426.0
HKD3_k127_1662815_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 414.0
HKD3_k127_1662815_6 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000000000000000002692 169.0
HKD3_k127_1662815_7 - - - - 0.00000000000000000000000000001885 120.0
HKD3_k127_1837377_0 MMPL family - - - 0.0 1284.0
HKD3_k127_1837377_1 Protein of unknown function (DUF1302) - - - 1.149e-320 992.0
HKD3_k127_1837377_10 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 580.0
HKD3_k127_1837377_11 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 576.0
HKD3_k127_1837377_12 CHASE4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 582.0
HKD3_k127_1837377_13 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 561.0
HKD3_k127_1837377_14 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 566.0
HKD3_k127_1837377_15 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 526.0
HKD3_k127_1837377_16 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 526.0
HKD3_k127_1837377_17 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 498.0
HKD3_k127_1837377_18 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 481.0
HKD3_k127_1837377_19 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
HKD3_k127_1837377_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.892e-293 904.0
HKD3_k127_1837377_20 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
HKD3_k127_1837377_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 434.0
HKD3_k127_1837377_22 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 423.0
HKD3_k127_1837377_23 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 400.0
HKD3_k127_1837377_24 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 414.0
HKD3_k127_1837377_25 Methyltransferase K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 404.0
HKD3_k127_1837377_26 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 404.0
HKD3_k127_1837377_27 Transcriptional regulator K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 395.0
HKD3_k127_1837377_28 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 381.0
HKD3_k127_1837377_29 phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 371.0
HKD3_k127_1837377_3 Belongs to the peptidase S8 family - - - 8.296e-292 929.0
HKD3_k127_1837377_30 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 353.0
HKD3_k127_1837377_31 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 349.0
HKD3_k127_1837377_32 Protein of unknown function (DUF2884) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 342.0
HKD3_k127_1837377_33 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
HKD3_k127_1837377_34 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
HKD3_k127_1837377_35 OmpW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 321.0
HKD3_k127_1837377_36 Nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 285.0
HKD3_k127_1837377_37 transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 294.0
HKD3_k127_1837377_38 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 299.0
HKD3_k127_1837377_39 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003788 272.0
HKD3_k127_1837377_4 dehydrogenase K00382 - 1.8.1.4 1.493e-291 905.0
HKD3_k127_1837377_40 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004436 278.0
HKD3_k127_1837377_41 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007149 266.0
HKD3_k127_1837377_42 antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001575 267.0
HKD3_k127_1837377_43 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001244 276.0
HKD3_k127_1837377_44 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
HKD3_k127_1837377_45 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000169 230.0
HKD3_k127_1837377_46 - - - - 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
HKD3_k127_1837377_47 lipocalin K03098 - - 0.000000000000000000000000000000000000000000000000000000001835 205.0
HKD3_k127_1837377_48 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000002563 214.0
HKD3_k127_1837377_49 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000009523 196.0
HKD3_k127_1837377_5 Protein of unknown function (DUF1329) - - - 1.212e-277 859.0
HKD3_k127_1837377_50 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000000000000002045 196.0
HKD3_k127_1837377_51 Polymorphic membrane protein - - - 0.00000000000000000000000000000000000000000000365 189.0
HKD3_k127_1837377_52 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000006458 167.0
HKD3_k127_1837377_53 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000006433 157.0
HKD3_k127_1837377_54 Cytochrome c - - - 0.000000000000000000000000000000000000001232 149.0
HKD3_k127_1837377_55 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000009766 154.0
HKD3_k127_1837377_56 Protein of unknown function (DUF3297) - - - 0.000000000000000000000000000000000006802 145.0
HKD3_k127_1837377_57 Outer membrane receptor - - - 0.0000000000000000000004804 100.0
HKD3_k127_1837377_59 Protein of unknown function (DUF1289) K06938 - - 0.000000000001214 72.0
HKD3_k127_1837377_6 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 637.0
HKD3_k127_1837377_60 EF-hand domain pair - - - 0.0000007738 62.0
HKD3_k127_1837377_7 oxidoreductase K09471 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 590.0
HKD3_k127_1837377_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 588.0
HKD3_k127_1837377_9 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 582.0
HKD3_k127_1909854_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 8.35e-320 982.0
HKD3_k127_1909854_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 8.924e-209 657.0
HKD3_k127_1909854_2 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 356.0
HKD3_k127_1909854_3 - - - - 0.00000000000000000000000068 115.0
HKD3_k127_2038844_0 M61 glycyl aminopeptidase - - - 0.0 1004.0
HKD3_k127_2038844_1 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 9.023e-251 792.0
HKD3_k127_2038844_10 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 350.0
HKD3_k127_2038844_11 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HKD3_k127_2038844_12 phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004269 279.0
HKD3_k127_2038844_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007833 274.0
HKD3_k127_2038844_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002707 278.0
HKD3_k127_2038844_15 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008378 273.0
HKD3_k127_2038844_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 253.0
HKD3_k127_2038844_18 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000039 210.0
HKD3_k127_2038844_19 (Barnase) inhibitor - - - 0.0000000000000000000000000000000000000000000000000003043 189.0
HKD3_k127_2038844_2 Lecithin:cholesterol acyltransferase - - - 7.457e-194 624.0
HKD3_k127_2038844_20 Belongs to the UPF0225 family K09858 - - 0.00000000000000000000000000000000000000000000000004984 181.0
HKD3_k127_2038844_22 - - - - 0.00000000000000002655 93.0
HKD3_k127_2038844_24 - - - - 0.0001528 51.0
HKD3_k127_2038844_3 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 549.0
HKD3_k127_2038844_4 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 546.0
HKD3_k127_2038844_5 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 542.0
HKD3_k127_2038844_6 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 552.0
HKD3_k127_2038844_7 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 456.0
HKD3_k127_2038844_8 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 391.0
HKD3_k127_2038844_9 Belongs to the UPF0149 family K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 374.0
HKD3_k127_2051461_0 GGDEF domain - - - 0.0 1416.0
HKD3_k127_2051461_1 ABC transporter K02031,K02032 - - 4.611e-207 677.0
HKD3_k127_2051461_10 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 340.0
HKD3_k127_2051461_11 Membrane - - - 0.0000000000000000000000000000000000000000000000009991 183.0
HKD3_k127_2051461_12 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000000001034 139.0
HKD3_k127_2051461_13 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000001062 138.0
HKD3_k127_2051461_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 599.0
HKD3_k127_2051461_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 578.0
HKD3_k127_2051461_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 526.0
HKD3_k127_2051461_5 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 487.0
HKD3_k127_2051461_6 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 460.0
HKD3_k127_2051461_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 439.0
HKD3_k127_2051461_8 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 428.0
HKD3_k127_2051461_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 409.0
HKD3_k127_2234258_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 2.056e-255 801.0
HKD3_k127_2234258_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 490.0
HKD3_k127_2234258_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 310.0
HKD3_k127_2234258_3 - - - - 0.000000000000000000000000000000003711 143.0
HKD3_k127_2271514_0 Helicase K03578 - 3.6.4.13 0.0 2087.0
HKD3_k127_2271514_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1134.0
HKD3_k127_2271514_2 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004363 299.0
HKD3_k127_2271514_3 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000001517 159.0
HKD3_k127_2294236_0 Phosphate starvation protein PhoH K07175 - - 1.295e-299 923.0
HKD3_k127_2294236_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.024e-245 765.0
HKD3_k127_2294236_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
HKD3_k127_2294236_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000000000606 223.0
HKD3_k127_2294236_12 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000125 244.0
HKD3_k127_2294236_13 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.00000000000000000000000000000000000000001993 170.0
HKD3_k127_2294236_14 Helix-turn-helix - - - 0.000000000000000000000000000000005689 129.0
HKD3_k127_2294236_15 alpha/beta hydrolase fold - - - 0.00000000003637 63.0
HKD3_k127_2294236_2 Sulfate transporter K03321 - - 2.413e-235 742.0
HKD3_k127_2294236_3 Belongs to the GPI family K01810 - 5.3.1.9 1.281e-229 720.0
HKD3_k127_2294236_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 7.19e-204 638.0
HKD3_k127_2294236_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 501.0
HKD3_k127_2294236_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 460.0
HKD3_k127_2294236_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 424.0
HKD3_k127_2294236_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 392.0
HKD3_k127_2294236_9 Glycine cleavage system regulatory protein K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 362.0
HKD3_k127_2308662_0 Efflux pump membrane transporter K19585 - - 0.0 1740.0
HKD3_k127_2308662_1 Cytochrome c - - - 0.0 1263.0
HKD3_k127_2308662_10 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 511.0
HKD3_k127_2308662_11 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 478.0
HKD3_k127_2308662_12 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 477.0
HKD3_k127_2308662_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 458.0
HKD3_k127_2308662_14 isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 304.0
HKD3_k127_2308662_15 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
HKD3_k127_2308662_16 short chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000001024 233.0
HKD3_k127_2308662_17 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000000000000000000000000000001957 205.0
HKD3_k127_2308662_2 Peptidase family M3 K01414 - 3.4.24.70 0.0 1150.0
HKD3_k127_2308662_3 Patatin-like phospholipase - - - 7.164e-303 979.0
HKD3_k127_2308662_4 Cytochrome c - - - 1.133e-256 805.0
HKD3_k127_2308662_5 7TM diverse intracellular signalling - - - 2.18e-239 754.0
HKD3_k127_2308662_6 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 587.0
HKD3_k127_2308662_7 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 560.0
HKD3_k127_2308662_8 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 528.0
HKD3_k127_2308662_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18298,K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 530.0
HKD3_k127_2414162_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 5.035e-209 657.0
HKD3_k127_2414162_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.171e-207 650.0
HKD3_k127_2414162_10 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000182 234.0
HKD3_k127_2414162_11 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000000001033 220.0
HKD3_k127_2414162_12 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000262 104.0
HKD3_k127_2414162_13 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000001002 86.0
HKD3_k127_2414162_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 575.0
HKD3_k127_2414162_3 UPF0761 membrane protein K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 511.0
HKD3_k127_2414162_4 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 445.0
HKD3_k127_2414162_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 417.0
HKD3_k127_2414162_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 408.0
HKD3_k127_2414162_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 381.0
HKD3_k127_2414162_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 377.0
HKD3_k127_2414162_9 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 285.0
HKD3_k127_2416207_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1688.0
HKD3_k127_2416207_1 Potassium transporter TrkA - - - 3.461e-275 858.0
HKD3_k127_2416207_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 452.0
HKD3_k127_2416207_11 XRE family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 444.0
HKD3_k127_2416207_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 426.0
HKD3_k127_2416207_13 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
HKD3_k127_2416207_14 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 376.0
HKD3_k127_2416207_15 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 285.0
HKD3_k127_2416207_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
HKD3_k127_2416207_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000033 209.0
HKD3_k127_2416207_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000008283 186.0
HKD3_k127_2416207_19 - - - - 0.000000000000000000000000000000000000000000000000002135 189.0
HKD3_k127_2416207_2 Sugar (and other) transporter - - - 3.66e-270 837.0
HKD3_k127_2416207_21 ferredoxin - - - 0.000000000000000000000000000001262 130.0
HKD3_k127_2416207_22 Thiamine biosynthesis protein K03154 - - 0.000000000000000000002483 94.0
HKD3_k127_2416207_23 - - - - 0.000393 48.0
HKD3_k127_2416207_3 aminopeptidase - - - 7.741e-228 714.0
HKD3_k127_2416207_4 Histidine kinase - - - 1.003e-195 617.0
HKD3_k127_2416207_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 561.0
HKD3_k127_2416207_6 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 515.0
HKD3_k127_2416207_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 493.0
HKD3_k127_2416207_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 475.0
HKD3_k127_2416207_9 HlyD membrane-fusion protein of T1SS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 487.0
HKD3_k127_2533917_0 3-hydroxyacyl-coa dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1227.0
HKD3_k127_2533917_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1210.0
HKD3_k127_2533917_10 MucB/RseB C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 481.0
HKD3_k127_2533917_11 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 484.0
HKD3_k127_2533917_12 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 436.0
HKD3_k127_2533917_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 419.0
HKD3_k127_2533917_14 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 396.0
HKD3_k127_2533917_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 374.0
HKD3_k127_2533917_16 protein conserved in bacteria K09973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 368.0
HKD3_k127_2533917_17 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
HKD3_k127_2533917_18 Rnf-Nqr subunit, membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
HKD3_k127_2533917_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001668 265.0
HKD3_k127_2533917_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1124.0
HKD3_k127_2533917_20 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
HKD3_k127_2533917_21 Predicted membrane protein (DUF2127) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005467 240.0
HKD3_k127_2533917_22 Anti sigma-E protein RseA, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000002097 221.0
HKD3_k127_2533917_23 ATPase or kinase K06925 - - 0.0000000000000000000000000000000000000000000000000000000127 214.0
HKD3_k127_2533917_24 RDD family - - - 0.000000000000000000000000000000000000000000000000002856 190.0
HKD3_k127_2533917_25 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000000001738 196.0
HKD3_k127_2533917_26 Domain of unknown function (DUF4845) - - - 0.000000000000256 77.0
HKD3_k127_2533917_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.125e-311 962.0
HKD3_k127_2533917_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.648e-268 828.0
HKD3_k127_2533917_5 ATP-binding protein K06915 - - 3.973e-260 837.0
HKD3_k127_2533917_6 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 5.057e-236 739.0
HKD3_k127_2533917_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.048e-219 697.0
HKD3_k127_2533917_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 3.051e-198 623.0
HKD3_k127_2533917_9 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 494.0
HKD3_k127_2607433_0 FtsX-like permease family K02004 - - 0.0 1084.0
HKD3_k127_2607433_1 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 612.0
HKD3_k127_2607433_10 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 324.0
HKD3_k127_2607433_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005116 273.0
HKD3_k127_2607433_12 signal transduction protein containing sensor and EAL domains - - - 0.00000000000000000000000000000000000000000000000000000000000000002633 245.0
HKD3_k127_2607433_13 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000158 205.0
HKD3_k127_2607433_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
HKD3_k127_2607433_15 - - - - 0.00000000000000000000000000000000000000000000000000000001214 203.0
HKD3_k127_2607433_16 Alkylphosphonate utilization operon protein K06193 - - 0.000000000000000000000000000000000000000000000004918 180.0
HKD3_k127_2607433_17 diguanylate cyclase K20961 - 2.7.7.65 0.00000000000000000000000000000000000000000000002111 175.0
HKD3_k127_2607433_18 Beta-lactamase - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD3_k127_2607433_19 - - - - 0.000000000000000000000000000000000000006103 150.0
HKD3_k127_2607433_2 dehydrogenase K00001,K12957 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 590.0
HKD3_k127_2607433_20 acetyltransferase K06975 - - 0.000000000000000000000000000000637 124.0
HKD3_k127_2607433_21 Histidine kinase - - - 0.000000000000000000000000000002296 128.0
HKD3_k127_2607433_23 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000007588 51.0
HKD3_k127_2607433_3 - K01387,K06399 - 3.4.21.116,3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 533.0
HKD3_k127_2607433_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 497.0
HKD3_k127_2607433_5 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 494.0
HKD3_k127_2607433_6 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 455.0
HKD3_k127_2607433_7 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 444.0
HKD3_k127_2607433_8 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 397.0
HKD3_k127_2607433_9 Beta-lactamase superfamily domain K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 373.0
HKD3_k127_2666218_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 0.0 1077.0
HKD3_k127_2666218_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0 1064.0
HKD3_k127_2666218_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 426.0
HKD3_k127_2666218_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 396.0
HKD3_k127_2666218_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 339.0
HKD3_k127_2666218_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 321.0
HKD3_k127_2666218_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 311.0
HKD3_k127_2666218_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 304.0
HKD3_k127_2666218_8 Protein of unknown function (DUF3011) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002196 246.0
HKD3_k127_2690795_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1475.0
HKD3_k127_2690795_1 diguanylate cyclase - - - 0.0 1375.0
HKD3_k127_2690795_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 425.0
HKD3_k127_2690795_11 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 418.0
HKD3_k127_2690795_12 Biopolymer transporter ExbB K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008518 398.0
HKD3_k127_2690795_13 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 383.0
HKD3_k127_2690795_14 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 373.0
HKD3_k127_2690795_15 LuxR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 374.0
HKD3_k127_2690795_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 309.0
HKD3_k127_2690795_17 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 312.0
HKD3_k127_2690795_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 291.0
HKD3_k127_2690795_19 transcriptional K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004733 266.0
HKD3_k127_2690795_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 5.839e-211 674.0
HKD3_k127_2690795_20 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001002 258.0
HKD3_k127_2690795_21 Biopolymer K03559 - - 0.000000000000000000000000000000000000000000000000000000000000000002414 228.0
HKD3_k127_2690795_22 Biopolymer K03559 - - 0.000000000000000000000000000000000000000000000000000005289 192.0
HKD3_k127_2690795_23 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000001614 130.0
HKD3_k127_2690795_24 Transglycosylase associated protein - - - 0.000000000000000000000000000001717 121.0
HKD3_k127_2690795_25 - - - - 0.000000000000000000005222 101.0
HKD3_k127_2690795_26 - - - - 0.0000000000000007321 87.0
HKD3_k127_2690795_3 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 1.838e-202 637.0
HKD3_k127_2690795_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 603.0
HKD3_k127_2690795_5 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 544.0
HKD3_k127_2690795_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 548.0
HKD3_k127_2690795_7 membrane protein terc K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 510.0
HKD3_k127_2690795_8 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 492.0
HKD3_k127_2690795_9 DNA repair photolyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 503.0
HKD3_k127_2692266_0 Outer membrane receptor - - - 0.0 1356.0
HKD3_k127_2692266_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1018.0
HKD3_k127_2692266_10 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 519.0
HKD3_k127_2692266_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 417.0
HKD3_k127_2692266_12 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 409.0
HKD3_k127_2692266_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 398.0
HKD3_k127_2692266_14 membrane transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 391.0
HKD3_k127_2692266_15 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 385.0
HKD3_k127_2692266_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 316.0
HKD3_k127_2692266_17 SURF1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 295.0
HKD3_k127_2692266_18 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000004596 259.0
HKD3_k127_2692266_19 Glutamyl-tRNA amidotransferase K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000000459 230.0
HKD3_k127_2692266_2 Lytic murein transglycosylase K08309 - - 1.306e-306 951.0
HKD3_k127_2692266_20 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000008626 203.0
HKD3_k127_2692266_21 signal sequence binding - - - 0.00000000000000000000000000000000106 139.0
HKD3_k127_2692266_22 PFAM VanZ - - - 0.00000000000000000000000000000001795 147.0
HKD3_k127_2692266_23 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001708 135.0
HKD3_k127_2692266_24 Protein of unknown function (DUF2909) - - - 0.00000000000000000000000008279 120.0
HKD3_k127_2692266_25 - - - - 0.0000000000000000000000001198 111.0
HKD3_k127_2692266_26 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000001691 87.0
HKD3_k127_2692266_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 3.141e-216 677.0
HKD3_k127_2692266_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 7.405e-202 646.0
HKD3_k127_2692266_5 cytochrome oxidase assembly K02259 - - 1.495e-194 611.0
HKD3_k127_2692266_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 592.0
HKD3_k127_2692266_7 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 591.0
HKD3_k127_2692266_8 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 538.0
HKD3_k127_2692266_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 529.0
HKD3_k127_2692269_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.0 1209.0
HKD3_k127_2692269_1 Outer membrane receptor - - - 0.0 1125.0
HKD3_k127_2692269_10 oxidase, subunit II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 530.0
HKD3_k127_2692269_11 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 447.0
HKD3_k127_2692269_12 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 423.0
HKD3_k127_2692269_13 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 437.0
HKD3_k127_2692269_14 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 368.0
HKD3_k127_2692269_15 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
HKD3_k127_2692269_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 365.0
HKD3_k127_2692269_17 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001974 277.0
HKD3_k127_2692269_18 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004271 275.0
HKD3_k127_2692269_19 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HKD3_k127_2692269_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.537e-317 975.0
HKD3_k127_2692269_20 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009072 251.0
HKD3_k127_2692269_21 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000537 210.0
HKD3_k127_2692269_22 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000009993 149.0
HKD3_k127_2692269_23 Domain of unknown function (DUF4190) - - - 0.0000000000000000000000000000000406 128.0
HKD3_k127_2692269_25 - - - - 0.0001562 54.0
HKD3_k127_2692269_3 oxidase, subunit - - - 1.143e-238 743.0
HKD3_k127_2692269_4 Sulfatase-modifying factor enzyme 1 - - - 1.32e-221 703.0
HKD3_k127_2692269_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 596.0
HKD3_k127_2692269_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 593.0
HKD3_k127_2692269_7 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 607.0
HKD3_k127_2692269_8 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 555.0
HKD3_k127_2692269_9 COG2202 FOG PAS PAC domain K21025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 525.0
HKD3_k127_2697831_0 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 0.0 1355.0
HKD3_k127_2697831_1 peptidase K07386 - - 0.0 1070.0
HKD3_k127_2697831_10 N-acyl-L-amino acid amidohydrolase K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 621.0
HKD3_k127_2697831_11 NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 560.0
HKD3_k127_2697831_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 489.0
HKD3_k127_2697831_13 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 482.0
HKD3_k127_2697831_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HKD3_k127_2697831_15 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 402.0
HKD3_k127_2697831_16 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 401.0
HKD3_k127_2697831_17 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 375.0
HKD3_k127_2697831_18 exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 339.0
HKD3_k127_2697831_19 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 305.0
HKD3_k127_2697831_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1028.0
HKD3_k127_2697831_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005581 280.0
HKD3_k127_2697831_21 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
HKD3_k127_2697831_22 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006438 235.0
HKD3_k127_2697831_23 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001956 228.0
HKD3_k127_2697831_24 SMART Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000003414 179.0
HKD3_k127_2697831_25 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000008439 173.0
HKD3_k127_2697831_26 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000167 181.0
HKD3_k127_2697831_27 PFAM DoxX K15977 - - 0.000000000000000000000000000000000000000003235 161.0
HKD3_k127_2697831_28 - - - - 0.00000000000000000000000000001045 130.0
HKD3_k127_2697831_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 1.561e-315 1024.0
HKD3_k127_2697831_4 Histidine kinase - - - 5.591e-293 921.0
HKD3_k127_2697831_5 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 8.333e-284 882.0
HKD3_k127_2697831_6 Amidohydrolase family - - - 1.111e-255 799.0
HKD3_k127_2697831_7 Nuclease K07004 - - 4.086e-243 765.0
HKD3_k127_2697831_8 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 8.998e-219 739.0
HKD3_k127_2697831_9 MASE1 - - - 1.201e-205 653.0
HKD3_k127_2729022_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.864e-307 956.0
HKD3_k127_2729022_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 3.648e-228 714.0
HKD3_k127_2729022_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.638e-216 710.0
HKD3_k127_2729022_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 610.0
HKD3_k127_2729022_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 509.0
HKD3_k127_2729022_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001012 273.0
HKD3_k127_2729022_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 242.0
HKD3_k127_2729022_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000003625 155.0
HKD3_k127_2729022_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000000000000003191 149.0
HKD3_k127_2732909_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1582.0
HKD3_k127_2732909_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1433.0
HKD3_k127_2732909_10 Protein tyrosine kinase - - - 2.03e-234 734.0
HKD3_k127_2732909_11 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 2.989e-208 650.0
HKD3_k127_2732909_12 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.056e-207 651.0
HKD3_k127_2732909_13 heptosyltransferase K12982 - - 5.014e-201 629.0
HKD3_k127_2732909_14 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 669.0
HKD3_k127_2732909_15 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 582.0
HKD3_k127_2732909_16 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 527.0
HKD3_k127_2732909_17 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 522.0
HKD3_k127_2732909_18 Catalyzes a key regulatory step in fatty acid biosynthesis K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 467.0
HKD3_k127_2732909_19 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 447.0
HKD3_k127_2732909_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1412.0
HKD3_k127_2732909_20 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 439.0
HKD3_k127_2732909_21 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 412.0
HKD3_k127_2732909_22 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 395.0
HKD3_k127_2732909_23 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 395.0
HKD3_k127_2732909_24 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 400.0
HKD3_k127_2732909_25 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 381.0
HKD3_k127_2732909_26 transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 370.0
HKD3_k127_2732909_27 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 366.0
HKD3_k127_2732909_28 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 346.0
HKD3_k127_2732909_29 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 341.0
HKD3_k127_2732909_3 Caspase domain - - - 0.0 1036.0
HKD3_k127_2732909_30 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 291.0
HKD3_k127_2732909_31 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002318 271.0
HKD3_k127_2732909_32 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000002524 262.0
HKD3_k127_2732909_33 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HKD3_k127_2732909_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
HKD3_k127_2732909_35 Outer membrane lipoprotein K07285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
HKD3_k127_2732909_36 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
HKD3_k127_2732909_37 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006888 238.0
HKD3_k127_2732909_38 Methyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001253 232.0
HKD3_k127_2732909_39 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HKD3_k127_2732909_4 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 1.136e-267 854.0
HKD3_k127_2732909_40 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001263 211.0
HKD3_k127_2732909_41 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000002024 188.0
HKD3_k127_2732909_42 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000000000000000000000000156 184.0
HKD3_k127_2732909_43 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000001345 181.0
HKD3_k127_2732909_44 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000008043 160.0
HKD3_k127_2732909_45 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001319 147.0
HKD3_k127_2732909_46 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000000000002314 121.0
HKD3_k127_2732909_47 Molybdopterin K03636 - - 0.0000000000000000000000000004147 126.0
HKD3_k127_2732909_48 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000009325 89.0
HKD3_k127_2732909_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.212e-267 826.0
HKD3_k127_2732909_50 - - - - 0.000000001938 59.0
HKD3_k127_2732909_51 - - - - 0.00000001457 59.0
HKD3_k127_2732909_52 - - - - 0.00000001737 55.0
HKD3_k127_2732909_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.125e-265 824.0
HKD3_k127_2732909_7 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.606e-264 820.0
HKD3_k127_2732909_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.158e-258 805.0
HKD3_k127_2732909_9 peptidylprolyl isomerase K03770 - 5.2.1.8 1.089e-255 804.0
HKD3_k127_2816963_0 gtp-binding protein K06207 - - 0.0 1115.0
HKD3_k127_2816963_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.804e-275 862.0
HKD3_k127_2816963_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001104 278.0
HKD3_k127_2816963_12 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008401 259.0
HKD3_k127_2816963_13 Ion channel - - - 0.0000000000000000000000000000000000000000000001859 174.0
HKD3_k127_2816963_2 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 1.119e-263 824.0
HKD3_k127_2816963_3 aminotransferase K00812 - 2.6.1.1 3.133e-243 769.0
HKD3_k127_2816963_4 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 3.817e-232 720.0
HKD3_k127_2816963_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 3.742e-198 620.0
HKD3_k127_2816963_6 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 550.0
HKD3_k127_2816963_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 531.0
HKD3_k127_2816963_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
HKD3_k127_2816963_9 Cell Wall - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 285.0
HKD3_k127_2882618_0 Malic enzyme K00029 - 1.1.1.40 0.0 1349.0
HKD3_k127_2882618_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 7.5e-322 1010.0
HKD3_k127_2882618_10 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000002521 204.0
HKD3_k127_2882618_11 Domain of unknown function (DUF4345) - - - 0.00000000000000000000000000000000000000000000000112 177.0
HKD3_k127_2882618_12 Acetyl-coenzyme A synthetase N-terminus - - - 0.000000000000111 74.0
HKD3_k127_2882618_2 aminotransferase K14260 - 2.6.1.2,2.6.1.66 9.528e-246 762.0
HKD3_k127_2882618_3 protein conserved in bacteria - - - 4.08e-220 706.0
HKD3_k127_2882618_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 609.0
HKD3_k127_2882618_5 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 547.0
HKD3_k127_2882618_6 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 550.0
HKD3_k127_2882618_7 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 428.0
HKD3_k127_2882618_8 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 306.0
HKD3_k127_2882618_9 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002182 263.0
HKD3_k127_2991814_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1453.0
HKD3_k127_2991814_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 2.586e-229 715.0
HKD3_k127_2991814_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 4.332e-219 700.0
HKD3_k127_2991814_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 362.0
HKD3_k127_2991814_4 protein conserved in bacteria K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 315.0
HKD3_k127_2991814_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 293.0
HKD3_k127_2991814_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003831 268.0
HKD3_k127_2991814_7 type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
HKD3_k127_2991814_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.0000000000000000000000000000000000002691 143.0
HKD3_k127_2991814_9 tRNA-binding protein K06878 - - 0.000000000000000001936 84.0
HKD3_k127_3040440_0 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1961.0
HKD3_k127_3040440_1 Heat shock 70 kDa protein K04043 - - 0.0 1133.0
HKD3_k127_3040440_10 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 585.0
HKD3_k127_3040440_11 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 479.0
HKD3_k127_3040440_12 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 368.0
HKD3_k127_3040440_13 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 312.0
HKD3_k127_3040440_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 306.0
HKD3_k127_3040440_15 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 299.0
HKD3_k127_3040440_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
HKD3_k127_3040440_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
HKD3_k127_3040440_18 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003355 250.0
HKD3_k127_3040440_19 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000323 251.0
HKD3_k127_3040440_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.474e-298 920.0
HKD3_k127_3040440_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000000000000002837 213.0
HKD3_k127_3040440_21 Enoyl-CoA hydratase/isomerase K13816 - - 0.00000000000000000000000171 103.0
HKD3_k127_3040440_3 Histidine kinase K10715 - 2.7.13.3 5.334e-284 889.0
HKD3_k127_3040440_4 Single-stranded-DNA-specific exonuclease K07462 - - 1.427e-274 866.0
HKD3_k127_3040440_5 Radical SAM superfamily - - - 5.5e-263 822.0
HKD3_k127_3040440_6 May be involved in recombinational repair of damaged DNA K03631 - - 5.845e-259 818.0
HKD3_k127_3040440_7 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 2.177e-232 722.0
HKD3_k127_3040440_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 5.803e-224 699.0
HKD3_k127_3040440_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 595.0
HKD3_k127_3103416_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1752.0
HKD3_k127_3103416_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1015.0
HKD3_k127_3103416_10 phenol hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 437.0
HKD3_k127_3103416_11 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
HKD3_k127_3103416_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 404.0
HKD3_k127_3103416_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 312.0
HKD3_k127_3103416_14 - - - - 0.0000000000000000000000000000000000000000000000000000002069 203.0
HKD3_k127_3103416_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000000001018 188.0
HKD3_k127_3103416_16 Transcriptional regulator K07729 - - 0.00000000000000000000001001 105.0
HKD3_k127_3103416_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000008713 87.0
HKD3_k127_3103416_18 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0006157 42.0
HKD3_k127_3103416_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.578e-243 762.0
HKD3_k127_3103416_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 3.055e-237 739.0
HKD3_k127_3103416_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 4.125e-215 681.0
HKD3_k127_3103416_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 6.944e-197 622.0
HKD3_k127_3103416_6 Sodium ABC transporter permease K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 612.0
HKD3_k127_3103416_7 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 524.0
HKD3_k127_3103416_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 512.0
HKD3_k127_3103416_9 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 481.0
HKD3_k127_3127248_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1235.0
HKD3_k127_3127248_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1125.0
HKD3_k127_3127248_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.258e-244 760.0
HKD3_k127_3127248_11 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.469e-242 751.0
HKD3_k127_3127248_12 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 4.742e-222 693.0
HKD3_k127_3127248_13 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 2.25e-207 662.0
HKD3_k127_3127248_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 9.388e-203 636.0
HKD3_k127_3127248_15 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 602.0
HKD3_k127_3127248_16 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 578.0
HKD3_k127_3127248_17 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 579.0
HKD3_k127_3127248_18 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 562.0
HKD3_k127_3127248_19 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 518.0
HKD3_k127_3127248_2 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.0 1074.0
HKD3_k127_3127248_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 490.0
HKD3_k127_3127248_21 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 466.0
HKD3_k127_3127248_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 475.0
HKD3_k127_3127248_23 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 439.0
HKD3_k127_3127248_24 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 441.0
HKD3_k127_3127248_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 433.0
HKD3_k127_3127248_26 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
HKD3_k127_3127248_27 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K03940 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 425.0
HKD3_k127_3127248_28 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 411.0
HKD3_k127_3127248_29 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 415.0
HKD3_k127_3127248_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1013.0
HKD3_k127_3127248_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 405.0
HKD3_k127_3127248_31 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 401.0
HKD3_k127_3127248_32 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 376.0
HKD3_k127_3127248_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 372.0
HKD3_k127_3127248_34 glycosylase K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 355.0
HKD3_k127_3127248_35 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 359.0
HKD3_k127_3127248_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 325.0
HKD3_k127_3127248_37 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 330.0
HKD3_k127_3127248_38 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 325.0
HKD3_k127_3127248_39 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
HKD3_k127_3127248_4 Participates in both transcription termination and antitermination K02600 - - 6.061e-302 929.0
HKD3_k127_3127248_40 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
HKD3_k127_3127248_41 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
HKD3_k127_3127248_42 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000001775 233.0
HKD3_k127_3127248_43 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000002085 208.0
HKD3_k127_3127248_44 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000000000000002404 171.0
HKD3_k127_3127248_45 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000009539 162.0
HKD3_k127_3127248_46 - - - - 0.00000000000000000000000000000000000000000001581 180.0
HKD3_k127_3127248_47 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000002129 175.0
HKD3_k127_3127248_48 - - - - 0.00000000000000000000000000000000001655 136.0
HKD3_k127_3127248_49 Protein of unknown function (DUF423) - - - 0.000000000000000000000004797 107.0
HKD3_k127_3127248_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.168e-294 904.0
HKD3_k127_3127248_50 protein conserved in bacteria - - - 0.000000000000000000000008444 102.0
HKD3_k127_3127248_51 Protein of unknown function (DUF3144) - - - 0.0000000001067 67.0
HKD3_k127_3127248_52 - - - - 0.0000001625 56.0
HKD3_k127_3127248_53 - - - - 0.0001533 51.0
HKD3_k127_3127248_6 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 4.009e-280 866.0
HKD3_k127_3127248_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.215e-277 852.0
HKD3_k127_3127248_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.875e-259 805.0
HKD3_k127_3127248_9 Tfp pilus assembly protein FimV K08086 - - 2.295e-254 809.0
HKD3_k127_3163260_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1184.0
HKD3_k127_3163260_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 1.683e-269 835.0
HKD3_k127_3163260_10 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 299.0
HKD3_k127_3163260_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000114 238.0
HKD3_k127_3163260_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000001825 142.0
HKD3_k127_3163260_2 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 1.213e-239 752.0
HKD3_k127_3163260_3 Histidine kinase K07636 - 2.7.13.3 1.168e-215 687.0
HKD3_k127_3163260_4 Glycosyl transferase - - - 4.736e-212 663.0
HKD3_k127_3163260_5 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 609.0
HKD3_k127_3163260_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 462.0
HKD3_k127_3163260_7 Two component response regulator for the phosphate regulon K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 443.0
HKD3_k127_3163260_8 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 334.0
HKD3_k127_3163260_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 305.0
HKD3_k127_3543981_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.0 1239.0
HKD3_k127_3543981_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 8.176e-307 945.0
HKD3_k127_3543981_2 synthase K00574 - 2.1.1.79 8.956e-203 636.0
HKD3_k127_3543981_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 395.0
HKD3_k127_3543981_4 - - - - 0.000000000000000000000000000000001426 138.0
HKD3_k127_3597904_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.088e-248 771.0
HKD3_k127_3597904_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 527.0
HKD3_k127_3597904_2 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HKD3_k127_3597904_3 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 515.0
HKD3_k127_3597904_4 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 488.0
HKD3_k127_3597904_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000001375 172.0
HKD3_k127_3672756_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 6.684e-293 916.0
HKD3_k127_3672756_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 2.472e-244 759.0
HKD3_k127_3672756_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000002394 219.0
HKD3_k127_3672756_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000002857 239.0
HKD3_k127_3672756_12 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000556 180.0
HKD3_k127_3672756_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 3.131e-230 719.0
HKD3_k127_3672756_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 5.401e-230 722.0
HKD3_k127_3672756_4 Histidine kinase - - - 3.754e-212 688.0
HKD3_k127_3672756_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 1.783e-200 632.0
HKD3_k127_3672756_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 604.0
HKD3_k127_3672756_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 588.0
HKD3_k127_3672756_8 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 482.0
HKD3_k127_3672756_9 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 427.0
HKD3_k127_3676000_0 MFS transporter K11381 - 1.2.4.4 0.0 1418.0
HKD3_k127_3676000_1 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.0 1036.0
HKD3_k127_3676000_10 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 535.0
HKD3_k127_3676000_11 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 525.0
HKD3_k127_3676000_12 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 490.0
HKD3_k127_3676000_13 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 488.0
HKD3_k127_3676000_14 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 468.0
HKD3_k127_3676000_15 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 459.0
HKD3_k127_3676000_16 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 462.0
HKD3_k127_3676000_17 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 442.0
HKD3_k127_3676000_18 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 416.0
HKD3_k127_3676000_19 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 389.0
HKD3_k127_3676000_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.222e-309 951.0
HKD3_k127_3676000_20 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
HKD3_k127_3676000_21 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 389.0
HKD3_k127_3676000_22 glutathione s-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 366.0
HKD3_k127_3676000_23 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 341.0
HKD3_k127_3676000_24 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 303.0
HKD3_k127_3676000_25 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 294.0
HKD3_k127_3676000_26 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 293.0
HKD3_k127_3676000_27 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 298.0
HKD3_k127_3676000_28 7,8-dihydro-8-oxoguanine-triphosphatase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 287.0
HKD3_k127_3676000_29 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
HKD3_k127_3676000_3 Carboxypeptidase - - - 2.968e-260 832.0
HKD3_k127_3676000_30 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001841 274.0
HKD3_k127_3676000_31 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009027 277.0
HKD3_k127_3676000_32 Protein of unknown function (DUF2652) - - - 0.0000000000000000000000000000000000000000000000000000000000000002249 244.0
HKD3_k127_3676000_33 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000001521 235.0
HKD3_k127_3676000_34 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
HKD3_k127_3676000_35 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000000000000000000000000000004379 188.0
HKD3_k127_3676000_36 Cold-shock protein K03704 - - 0.0000000000000000000000000000000000000009414 149.0
HKD3_k127_3676000_37 Outer Membrane Lipoprotein K06077 - - 0.000000000000000000000000000000000000002368 165.0
HKD3_k127_3676000_38 Cold-shock K03704 - - 0.0000000000000000000000000000000000006565 141.0
HKD3_k127_3676000_39 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000003077 139.0
HKD3_k127_3676000_4 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 1.738e-244 760.0
HKD3_k127_3676000_40 - - - - 0.00000000000000000000001015 111.0
HKD3_k127_3676000_41 Acetyltransferase (GNAT) domain K22441 - 2.3.1.57 0.00000000000000000000005749 113.0
HKD3_k127_3676000_42 - - - - 0.000000000000000000001692 99.0
HKD3_k127_3676000_44 - - - - 0.0000000003495 62.0
HKD3_k127_3676000_5 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 1.637e-242 762.0
HKD3_k127_3676000_6 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate - - - 2.77e-210 662.0
HKD3_k127_3676000_7 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008244 609.0
HKD3_k127_3676000_8 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 610.0
HKD3_k127_3676000_9 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 578.0
HKD3_k127_3739259_0 aminopeptidase K01263 - 3.4.11.14 0.0 1420.0
HKD3_k127_3739259_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1120.0
HKD3_k127_3739259_10 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 593.0
HKD3_k127_3739259_11 hydroxylase K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 567.0
HKD3_k127_3739259_12 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 569.0
HKD3_k127_3739259_13 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 510.0
HKD3_k127_3739259_14 Exodeoxyribonuclease IX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
HKD3_k127_3739259_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 455.0
HKD3_k127_3739259_16 endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 356.0
HKD3_k127_3739259_17 C-terminal domain of 1-Cys peroxiredoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 351.0
HKD3_k127_3739259_18 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 356.0
HKD3_k127_3739259_19 adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 356.0
HKD3_k127_3739259_2 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1009.0
HKD3_k127_3739259_20 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 324.0
HKD3_k127_3739259_21 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 310.0
HKD3_k127_3739259_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 317.0
HKD3_k127_3739259_23 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 296.0
HKD3_k127_3739259_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
HKD3_k127_3739259_25 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 294.0
HKD3_k127_3739259_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 285.0
HKD3_k127_3739259_27 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
HKD3_k127_3739259_28 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 258.0
HKD3_k127_3739259_29 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008856 262.0
HKD3_k127_3739259_3 Protein of unknown function (DUF1631) - - - 1.942e-264 833.0
HKD3_k127_3739259_30 deaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000001636 243.0
HKD3_k127_3739259_31 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000007624 223.0
HKD3_k127_3739259_32 4TM region of pyridine nucleotide transhydrogenase, mitoch - - - 0.000000000000000000000000000000000000000000001021 173.0
HKD3_k127_3739259_33 EF hand - - - 0.0000000000000000000000000000000000000001956 156.0
HKD3_k127_3739259_34 - - - - 0.000000000000000000000000000000000000006683 149.0
HKD3_k127_3739259_35 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000000000000000007423 150.0
HKD3_k127_3739259_36 - - - - 0.000000000000000000000000001972 127.0
HKD3_k127_3739259_37 acetoin utilization protein - - - 0.0000000000000000000000006024 106.0
HKD3_k127_3739259_38 - - - - 0.00000000000000000004432 104.0
HKD3_k127_3739259_4 Alkyl hydroperoxide reductase K03387 - - 1.565e-263 821.0
HKD3_k127_3739259_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 8.531e-260 808.0
HKD3_k127_3739259_6 Diguanylate cyclase, GGDEF domain - - - 5.34e-221 708.0
HKD3_k127_3739259_7 Cysteine-rich domain - - - 1.604e-207 652.0
HKD3_k127_3739259_8 NADP transhydrogenase K00324 - 1.6.1.2 6.738e-197 617.0
HKD3_k127_3739259_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 4.458e-196 615.0
HKD3_k127_3803526_0 GGDEF domain - - - 0.0 1363.0
HKD3_k127_3803526_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 4.692e-273 848.0
HKD3_k127_3803526_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
HKD3_k127_3803526_11 dna polymerase III K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002595 257.0
HKD3_k127_3803526_12 - - - - 0.000000000000000000000000000000000000000000000006248 177.0
HKD3_k127_3803526_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000000000000003264 160.0
HKD3_k127_3803526_14 Belongs to the ompA family K03286 - - 0.00000000000000000000000002335 112.0
HKD3_k127_3803526_15 EF-hand, calcium binding motif - - - 0.000000000000000000000001001 109.0
HKD3_k127_3803526_2 aminopeptidase K01262 - 3.4.11.9 2.034e-256 796.0
HKD3_k127_3803526_3 Domain of unknown function (DUF4915) - - - 2.979e-220 688.0
HKD3_k127_3803526_4 Cyclic nucleotide-monophosphate binding domain - - - 2.909e-198 622.0
HKD3_k127_3803526_5 permease K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 496.0
HKD3_k127_3803526_6 overlaps another CDS with the same product name K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 492.0
HKD3_k127_3803526_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 343.0
HKD3_k127_3803526_8 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 289.0
HKD3_k127_3803526_9 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001033 274.0
HKD3_k127_3818102_0 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 501.0
HKD3_k127_3818102_1 SET domain K07117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004996 275.0
HKD3_k127_3818102_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000395 252.0
HKD3_k127_3818102_3 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000149 137.0
HKD3_k127_3818102_4 SnoaL-like polyketide cyclase - - - 0.000000000000000000000008215 101.0
HKD3_k127_3894296_0 Amidohydrolase family - - - 0.0 1735.0
HKD3_k127_3894296_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0 1026.0
HKD3_k127_3894296_10 ABC transporter K18480 - - 0.000000000000000000000000000000000000000000000001698 195.0
HKD3_k127_3894296_11 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000005419 148.0
HKD3_k127_3894296_12 - - - - 0.0000000000000000000000000000000000005874 162.0
HKD3_k127_3894296_13 - - - - 0.00000000000000000000000001275 116.0
HKD3_k127_3894296_14 - - - - 0.00000000000000005493 85.0
HKD3_k127_3894296_2 amidohydrolase - - - 7.04e-250 775.0
HKD3_k127_3894296_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 578.0
HKD3_k127_3894296_4 Glutaredoxin K07390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 531.0
HKD3_k127_3894296_5 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 487.0
HKD3_k127_3894296_6 protein conserved in bacteria containing a divergent form of TPR repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 406.0
HKD3_k127_3894296_7 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 373.0
HKD3_k127_3894296_8 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 362.0
HKD3_k127_3894296_9 alkylated DNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 288.0
HKD3_k127_390501_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 1.104e-230 718.0
HKD3_k127_390501_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 2.706e-228 709.0
HKD3_k127_390501_2 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 559.0
HKD3_k127_390501_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 297.0
HKD3_k127_390501_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000005557 211.0
HKD3_k127_390501_5 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000000005012 191.0
HKD3_k127_390501_6 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000000003583 173.0
HKD3_k127_4030393_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1598.0
HKD3_k127_4030393_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1249.0
HKD3_k127_4030393_10 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 467.0
HKD3_k127_4030393_11 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 462.0
HKD3_k127_4030393_12 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 457.0
HKD3_k127_4030393_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 434.0
HKD3_k127_4030393_14 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 409.0
HKD3_k127_4030393_15 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 419.0
HKD3_k127_4030393_16 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 426.0
HKD3_k127_4030393_17 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 411.0
HKD3_k127_4030393_18 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 384.0
HKD3_k127_4030393_19 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 345.0
HKD3_k127_4030393_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1163.0
HKD3_k127_4030393_20 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 345.0
HKD3_k127_4030393_21 Ion transporter K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 356.0
HKD3_k127_4030393_22 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 334.0
HKD3_k127_4030393_23 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 333.0
HKD3_k127_4030393_24 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 300.0
HKD3_k127_4030393_25 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 293.0
HKD3_k127_4030393_26 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004711 294.0
HKD3_k127_4030393_27 Glyoxalase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001242 265.0
HKD3_k127_4030393_28 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005533 247.0
HKD3_k127_4030393_29 Transcriptional regulator K18301 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
HKD3_k127_4030393_3 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 2.115e-247 767.0
HKD3_k127_4030393_30 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001628 236.0
HKD3_k127_4030393_31 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000005017 177.0
HKD3_k127_4030393_32 - - - - 0.0000000000000000000000000000000000008498 147.0
HKD3_k127_4030393_34 protein conserved in bacteria - - - 0.00000000000000000000000000000007038 126.0
HKD3_k127_4030393_35 rubredoxin - - - 0.000000000000000000000000000001202 121.0
HKD3_k127_4030393_36 - - - - 0.0000000000000000007097 96.0
HKD3_k127_4030393_37 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.0000000000005176 70.0
HKD3_k127_4030393_4 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.904e-244 761.0
HKD3_k127_4030393_5 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 2.587e-220 702.0
HKD3_k127_4030393_6 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.798e-218 683.0
HKD3_k127_4030393_7 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 1.017e-207 649.0
HKD3_k127_4030393_8 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 506.0
HKD3_k127_4030393_9 dehydrogenase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 497.0
HKD3_k127_4111620_0 Cell division protein ftsk K03466 - - 0.0 1321.0
HKD3_k127_4111620_1 Recombination factor protein RarA K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 486.0
HKD3_k127_4111620_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 346.0
HKD3_k127_4283512_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 0.0 1504.0
HKD3_k127_4283512_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1071.0
HKD3_k127_4283512_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 470.0
HKD3_k127_4283512_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 406.0
HKD3_k127_4283512_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 363.0
HKD3_k127_4283512_5 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006146 256.0
HKD3_k127_4339054_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 559.0
HKD3_k127_4339054_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
HKD3_k127_4339054_2 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 324.0
HKD3_k127_4339054_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000003835 193.0
HKD3_k127_4339054_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000738 175.0
HKD3_k127_4401575_0 Dak2 K07030 - - 6.651e-285 893.0
HKD3_k127_4401575_1 two-component system sensor protein K07637 - 2.7.13.3 5.391e-222 696.0
HKD3_k127_4401575_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 445.0
HKD3_k127_4401575_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 383.0
HKD3_k127_4401575_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002298 270.0
HKD3_k127_4401575_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000002299 203.0
HKD3_k127_4401575_6 - - - - 0.00000000000000001289 89.0
HKD3_k127_4401575_8 protein conserved in bacteria containing a pentein-type domain - - - 0.0000000239 55.0
HKD3_k127_4428028_0 peptidase M20 - - - 3.881e-298 917.0
HKD3_k127_4428028_1 receptor K16090 - - 9.95e-290 907.0
HKD3_k127_4428028_10 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD3_k127_4428028_11 Cupin domain - - - 0.0000000000000000000000000000000000002126 153.0
HKD3_k127_4428028_12 competence protein ComEA K02237 - - 0.0000000000000000000000000000000000006483 149.0
HKD3_k127_4428028_13 Transglycosylase associated protein - - - 0.000003484 53.0
HKD3_k127_4428028_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 8.629e-215 677.0
HKD3_k127_4428028_3 abc transporter, permease K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 542.0
HKD3_k127_4428028_4 Part of SUF system involved in inserting iron-sulfur clusters into proteins K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 464.0
HKD3_k127_4428028_5 Cysteine desulfurase activator complex subunit SufB K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 418.0
HKD3_k127_4428028_6 HutD K09975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
HKD3_k127_4428028_7 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 282.0
HKD3_k127_4428028_8 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000279 278.0
HKD3_k127_4428028_9 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000000000000000000000000000000004427 203.0
HKD3_k127_4500080_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1062.0
HKD3_k127_4500080_1 Ubiquinone biosynthesis protein K03688 - - 5.4e-296 915.0
HKD3_k127_4500080_10 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 290.0
HKD3_k127_4500080_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
HKD3_k127_4500080_12 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000000000005236 191.0
HKD3_k127_4500080_13 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.0000000000000000000000000000000000000000000000000008105 204.0
HKD3_k127_4500080_14 Predicted integral membrane protein (DUF2269) - - - 0.00000000000000000000000000000000000000000000000003628 200.0
HKD3_k127_4500080_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000006693 184.0
HKD3_k127_4500080_16 RNA-binding protein K14761 - - 0.000000000000000000000009992 113.0
HKD3_k127_4500080_17 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000006926 77.0
HKD3_k127_4500080_2 AlkA N-terminal domain K13529 - 3.2.2.21 6.716e-230 717.0
HKD3_k127_4500080_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 527.0
HKD3_k127_4500080_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 484.0
HKD3_k127_4500080_5 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 481.0
HKD3_k127_4500080_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 464.0
HKD3_k127_4500080_7 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 460.0
HKD3_k127_4500080_8 Drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
HKD3_k127_4500080_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 312.0
HKD3_k127_4548217_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.98e-261 823.0
HKD3_k127_4548217_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.479e-205 657.0
HKD3_k127_4548217_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 579.0
HKD3_k127_4548217_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 597.0
HKD3_k127_4548217_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 535.0
HKD3_k127_4548217_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 348.0
HKD3_k127_4711151_0 ankyrin repeat K06867 - - 0.0 1439.0
HKD3_k127_4711151_1 peptidase - - - 0.0 1307.0
HKD3_k127_4711151_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 5.85e-300 928.0
HKD3_k127_4711151_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.746e-287 889.0
HKD3_k127_4711151_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 594.0
HKD3_k127_4711151_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000004999 205.0
HKD3_k127_4711151_6 YcgL domain-containing protein K09902 - - 0.00000000000000000000000000000003491 132.0
HKD3_k127_4711151_8 Patatin-like phospholipase K07001 - - 0.00000000001168 76.0
HKD3_k127_4713997_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1668.0
HKD3_k127_4713997_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1099.0
HKD3_k127_4713997_10 ABC-type multidrug transport system, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 449.0
HKD3_k127_4713997_11 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 415.0
HKD3_k127_4713997_12 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 429.0
HKD3_k127_4713997_13 Acyltransferase family K11941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 407.0
HKD3_k127_4713997_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 340.0
HKD3_k127_4713997_15 flavodoxin nitric oxide synthase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 294.0
HKD3_k127_4713997_16 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 290.0
HKD3_k127_4713997_17 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004346 269.0
HKD3_k127_4713997_18 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002034 273.0
HKD3_k127_4713997_19 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002383 261.0
HKD3_k127_4713997_2 lysine biosynthetic process via aminoadipic acid - - - 2.88e-208 659.0
HKD3_k127_4713997_20 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009191 240.0
HKD3_k127_4713997_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001261 231.0
HKD3_k127_4713997_22 cytochrome K17230 - - 0.00000000000000000000000000000000000000000000000000000000000000001549 244.0
HKD3_k127_4713997_24 Putative inner membrane exporter, YdcZ - - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
HKD3_k127_4713997_25 glutathione transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000009523 221.0
HKD3_k127_4713997_26 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000002556 214.0
HKD3_k127_4713997_27 MAPEG family - - - 0.00000000000000000000000000000000000000000000000000000007344 199.0
HKD3_k127_4713997_28 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000961 182.0
HKD3_k127_4713997_29 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000007404 186.0
HKD3_k127_4713997_3 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 579.0
HKD3_k127_4713997_30 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000001156 183.0
HKD3_k127_4713997_31 Protein of unknown function (DUF2938) - - - 0.00000000000000000000000000000000000000000000000018 188.0
HKD3_k127_4713997_32 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000004271 173.0
HKD3_k127_4713997_33 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000468 171.0
HKD3_k127_4713997_34 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000001004 157.0
HKD3_k127_4713997_35 Catabolite gene activator and regulatory subunit of cAMP-dependent protein K10914 - - 0.0000000000000000000000000000000000000000395 161.0
HKD3_k127_4713997_36 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000009381 155.0
HKD3_k127_4713997_37 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000008556 146.0
HKD3_k127_4713997_38 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000003503 147.0
HKD3_k127_4713997_39 - - - - 0.00000000000000000000000000000000006803 147.0
HKD3_k127_4713997_4 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 561.0
HKD3_k127_4713997_40 Glyoxalase-like domain - - - 0.000000000000000000000000000000000316 136.0
HKD3_k127_4713997_41 LTXXQ motif family protein - - - 0.00000000000000000000000007197 117.0
HKD3_k127_4713997_42 Erythromycin esterase K06880 - - 0.00000000000000000000000147 121.0
HKD3_k127_4713997_43 PFAM Cyclic nucleotide-binding domain - - - 0.00000000000000000004252 104.0
HKD3_k127_4713997_44 Protein of unknown function (DUF2798) - - - 0.000000000000000005878 96.0
HKD3_k127_4713997_45 - - - - 0.000000000009202 73.0
HKD3_k127_4713997_46 Protein of unknown function (DUF2798) - - - 0.00007463 45.0
HKD3_k127_4713997_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
HKD3_k127_4713997_6 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 493.0
HKD3_k127_4713997_7 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 483.0
HKD3_k127_4713997_8 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 498.0
HKD3_k127_4713997_9 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 454.0
HKD3_k127_4835178_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1877.0
HKD3_k127_4835178_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1032.0
HKD3_k127_4835178_10 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 421.0
HKD3_k127_4835178_11 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 377.0
HKD3_k127_4835178_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 381.0
HKD3_k127_4835178_13 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 366.0
HKD3_k127_4835178_14 hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 336.0
HKD3_k127_4835178_15 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 310.0
HKD3_k127_4835178_16 cytochrome c oxidase assembly protein K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 302.0
HKD3_k127_4835178_17 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 284.0
HKD3_k127_4835178_18 Aspartyl asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001611 259.0
HKD3_k127_4835178_19 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003379 244.0
HKD3_k127_4835178_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 5e-324 996.0
HKD3_k127_4835178_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000006582 235.0
HKD3_k127_4835178_21 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000003552 233.0
HKD3_k127_4835178_22 - - - - 0.000000000000000000000000000000000000000000000000004369 184.0
HKD3_k127_4835178_23 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000000000001528 186.0
HKD3_k127_4835178_24 Globin - - - 0.00000000000000000000000000000000000000000009747 165.0
HKD3_k127_4835178_25 transcriptional K03892 - - 0.000000000000000000000000000000000000001189 154.0
HKD3_k127_4835178_27 Belongs to the AB hydrolase superfamily. MetX family K00641 - 2.3.1.31 0.0000001555 59.0
HKD3_k127_4835178_3 Acetyl-CoA dehydrogenase C-terminal like - - - 2.3e-297 921.0
HKD3_k127_4835178_4 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 557.0
HKD3_k127_4835178_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 490.0
HKD3_k127_4835178_6 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 496.0
HKD3_k127_4835178_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 478.0
HKD3_k127_4835178_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 475.0
HKD3_k127_4835178_9 metal-dependent membrane protease K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 435.0
HKD3_k127_4936079_0 Oar protein - - - 1.571e-264 829.0
HKD3_k127_4936079_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 2.777e-198 632.0
HKD3_k127_4936079_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 453.0
HKD3_k127_4936079_3 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 413.0
HKD3_k127_4936079_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 387.0
HKD3_k127_4936079_5 UPF0056 membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 336.0
HKD3_k127_4936079_6 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
HKD3_k127_4936079_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000008145 261.0
HKD3_k127_4936079_8 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000001586 196.0
HKD3_k127_4936079_9 Trm112p-like protein - - - 0.0000000000000000000000000000000000002313 142.0
HKD3_k127_4949904_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 1.14e-233 728.0
HKD3_k127_4949904_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 5.438e-225 698.0
HKD3_k127_4949904_2 pathogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 383.0
HKD3_k127_4949904_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
HKD3_k127_4949904_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 331.0
HKD3_k127_4949904_5 fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 317.0
HKD3_k127_4960865_0 dna polymerase K02337 - 2.7.7.7 0.0 1793.0
HKD3_k127_4960865_1 membrane - - - 0.0 1623.0
HKD3_k127_4960865_10 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 466.0
HKD3_k127_4960865_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 466.0
HKD3_k127_4960865_12 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 455.0
HKD3_k127_4960865_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 458.0
HKD3_k127_4960865_14 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 434.0
HKD3_k127_4960865_15 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 341.0
HKD3_k127_4960865_16 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 359.0
HKD3_k127_4960865_17 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
HKD3_k127_4960865_18 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 288.0
HKD3_k127_4960865_19 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001396 278.0
HKD3_k127_4960865_2 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1585.0
HKD3_k127_4960865_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003213 259.0
HKD3_k127_4960865_21 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000221 256.0
HKD3_k127_4960865_22 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000000000000000000000000000000000002878 236.0
HKD3_k127_4960865_23 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000000000008612 218.0
HKD3_k127_4960865_24 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000005126 191.0
HKD3_k127_4960865_25 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000000000000000000000000000004759 181.0
HKD3_k127_4960865_26 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000000000002644 141.0
HKD3_k127_4960865_3 Protein tyrosine kinase K11912 - 2.7.11.1 1.44e-299 938.0
HKD3_k127_4960865_4 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 1.51e-267 831.0
HKD3_k127_4960865_5 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 4.716e-221 695.0
HKD3_k127_4960865_6 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 594.0
HKD3_k127_4960865_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 581.0
HKD3_k127_4960865_8 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 578.0
HKD3_k127_4960865_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 482.0
HKD3_k127_5032370_0 peptidase - - - 5.786e-294 910.0
HKD3_k127_5032370_1 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 344.0
HKD3_k127_5032370_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007696 285.0
HKD3_k127_50897_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 597.0
HKD3_k127_50897_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 593.0
HKD3_k127_50897_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 290.0
HKD3_k127_50897_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 284.0
HKD3_k127_50897_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001051 207.0
HKD3_k127_50897_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000005248 131.0
HKD3_k127_5205367_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0 1064.0
HKD3_k127_5205367_1 7TMR-DISM extracellular 2 - - - 3.303e-311 979.0
HKD3_k127_5205367_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 426.0
HKD3_k127_5205367_11 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 383.0
HKD3_k127_5205367_12 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 377.0
HKD3_k127_5205367_13 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 334.0
HKD3_k127_5205367_14 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 330.0
HKD3_k127_5205367_15 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 329.0
HKD3_k127_5205367_16 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 309.0
HKD3_k127_5205367_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003418 302.0
HKD3_k127_5205367_18 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 235.0
HKD3_k127_5205367_19 protein, YerC YecD - - - 0.000000000000000000000000000000000000000325 153.0
HKD3_k127_5205367_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 6.803e-251 779.0
HKD3_k127_5205367_20 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.00000000000000000000000000003076 123.0
HKD3_k127_5205367_3 calcineurin phosphoesterase - - - 1.029e-229 722.0
HKD3_k127_5205367_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 9.697e-208 657.0
HKD3_k127_5205367_5 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 594.0
HKD3_k127_5205367_6 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 548.0
HKD3_k127_5205367_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 516.0
HKD3_k127_5205367_8 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 449.0
HKD3_k127_5205367_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 458.0
HKD3_k127_5219678_0 aminopeptidase K01256 - 3.4.11.2 0.0 1253.0
HKD3_k127_5219678_1 GGDEF domain K21023 - 2.7.7.65 1.304e-284 904.0
HKD3_k127_5219678_2 Double sensory domain of two-component sensor kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 529.0
HKD3_k127_5219678_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 448.0
HKD3_k127_5219678_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000006265 206.0
HKD3_k127_5219678_5 Bacterial protein of unknown function (DUF922) - - - 0.00006142 47.0
HKD3_k127_5380999_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1737.0
HKD3_k127_5380999_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1724.0
HKD3_k127_5380999_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 521.0
HKD3_k127_5380999_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 497.0
HKD3_k127_5380999_12 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 449.0
HKD3_k127_5380999_13 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 388.0
HKD3_k127_5380999_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 394.0
HKD3_k127_5380999_15 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 380.0
HKD3_k127_5380999_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 327.0
HKD3_k127_5380999_17 Poly(hydroxyalcanoate) granule associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001016 243.0
HKD3_k127_5380999_18 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000003552 233.0
HKD3_k127_5380999_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000006376 236.0
HKD3_k127_5380999_2 GGDEF domain - - - 0.0 1624.0
HKD3_k127_5380999_20 cytochrome - - - 0.000000000000000000000000000000000000000000000000000001914 192.0
HKD3_k127_5380999_21 Cytochrome c - - - 0.00000000000000000000000000000000000000000001005 171.0
HKD3_k127_5380999_22 Acyl CoA binding protein - - - 0.0000000000000000000000000000000000000000007066 158.0
HKD3_k127_5380999_23 - - - - 0.0000000000000000000000000000000000000000009258 173.0
HKD3_k127_5380999_24 polyhydroxyalkanoic acid - - - 0.000000000000000000000000000000001763 131.0
HKD3_k127_5380999_25 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000000005023 83.0
HKD3_k127_5380999_3 Male sterility protein - - - 0.0 1210.0
HKD3_k127_5380999_4 Patatin-like phospholipase - - - 2.024e-219 692.0
HKD3_k127_5380999_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 6.509e-212 664.0
HKD3_k127_5380999_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 2.419e-210 656.0
HKD3_k127_5380999_7 trab family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 586.0
HKD3_k127_5380999_8 Belongs to the agmatine deiminase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 582.0
HKD3_k127_5380999_9 Acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 550.0
HKD3_k127_5382807_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 566.0
HKD3_k127_5382807_1 phosphate-selective porin K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 566.0
HKD3_k127_5382807_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 544.0
HKD3_k127_5382807_3 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 497.0
HKD3_k127_5382807_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 392.0
HKD3_k127_5382807_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 284.0
HKD3_k127_5382807_6 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002016 273.0
HKD3_k127_5382807_7 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000008845 235.0
HKD3_k127_5382807_8 Rnf-Nqr subunit, membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000005147 219.0
HKD3_k127_5382807_9 Part of a membrane complex involved in electron transport - - - 0.0000000000000000137 81.0
HKD3_k127_545787_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1776.0
HKD3_k127_545787_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1556.0
HKD3_k127_545787_10 thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000004617 218.0
HKD3_k127_545787_11 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000005239 176.0
HKD3_k127_545787_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000000000532 177.0
HKD3_k127_545787_13 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000004812 171.0
HKD3_k127_545787_14 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000000001438 168.0
HKD3_k127_545787_15 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000002787 147.0
HKD3_k127_545787_16 lipid binding - - - 0.0000000000000000000000000000000000006572 154.0
HKD3_k127_545787_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.488e-273 848.0
HKD3_k127_545787_3 Domain of unknown function (DUF4139) - - - 1.687e-220 696.0
HKD3_k127_545787_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.161e-212 662.0
HKD3_k127_545787_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 566.0
HKD3_k127_545787_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 510.0
HKD3_k127_545787_7 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 469.0
HKD3_k127_545787_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 400.0
HKD3_k127_545787_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000002142 233.0
HKD3_k127_558388_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0 1027.0
HKD3_k127_558388_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009622 344.0
HKD3_k127_5621020_0 DNA helicase K03654 - 3.6.4.12 2.829e-313 968.0
HKD3_k127_5621020_1 Involved in the TonB-independent uptake of proteins K03641 - - 1.962e-246 788.0
HKD3_k127_5621020_10 Biopolymer transport protein K03560 - - 0.000000000000000000000000000000000000000000000000000000000257 209.0
HKD3_k127_5621020_11 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000001385 203.0
HKD3_k127_5621020_12 - - - - 0.0005491 44.0
HKD3_k127_5621020_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 412.0
HKD3_k127_5621020_3 TolQ protein K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 405.0
HKD3_k127_5621020_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 368.0
HKD3_k127_5621020_5 Membrane protein TolA K03646 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 339.0
HKD3_k127_5621020_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 311.0
HKD3_k127_5621020_7 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 301.0
HKD3_k127_5621020_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 304.0
HKD3_k127_5621020_9 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 295.0
HKD3_k127_5769212_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1977.0
HKD3_k127_5769212_1 Cytochrome C biogenesis K02198 - - 0.0 1120.0
HKD3_k127_5769212_10 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 608.0
HKD3_k127_5769212_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 619.0
HKD3_k127_5769212_12 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 566.0
HKD3_k127_5769212_13 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 500.0
HKD3_k127_5769212_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 484.0
HKD3_k127_5769212_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 451.0
HKD3_k127_5769212_16 carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 435.0
HKD3_k127_5769212_17 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 394.0
HKD3_k127_5769212_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 385.0
HKD3_k127_5769212_19 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 384.0
HKD3_k127_5769212_2 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 5.546e-299 923.0
HKD3_k127_5769212_20 Cytochrome C biogenesis K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 379.0
HKD3_k127_5769212_21 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 353.0
HKD3_k127_5769212_22 Peptidoglycan-synthase activator LpoB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 350.0
HKD3_k127_5769212_23 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 348.0
HKD3_k127_5769212_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 332.0
HKD3_k127_5769212_25 Thiol disulfide interchange protein K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 320.0
HKD3_k127_5769212_27 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 312.0
HKD3_k127_5769212_29 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000009512 231.0
HKD3_k127_5769212_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.572e-273 856.0
HKD3_k127_5769212_30 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000000000000000000008499 219.0
HKD3_k127_5769212_31 Protein of unknown function (DUF3011) - - - 0.000000000000000000000000000000000000000000000000000781 191.0
HKD3_k127_5769212_32 BolA family transcriptional regulator K09780 - - 0.0000000000000000000000000000000000000000000000002363 177.0
HKD3_k127_5769212_33 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000000000000006378 141.0
HKD3_k127_5769212_34 diguanylate cyclase - - - 0.00000000000000000000000000000001694 128.0
HKD3_k127_5769212_4 - - - - 3.323e-258 805.0
HKD3_k127_5769212_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 6.063e-227 736.0
HKD3_k127_5769212_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.6e-221 691.0
HKD3_k127_5769212_7 aminotransferase K14287 - 2.6.1.88 8.807e-214 676.0
HKD3_k127_5769212_8 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 1.02e-200 648.0
HKD3_k127_5769212_9 diguanylate cyclase - - - 5.918e-194 646.0
HKD3_k127_5805564_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1746.0
HKD3_k127_5805564_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1600.0
HKD3_k127_5805564_10 acetyl-coa hydrolase - - - 1.828e-271 849.0
HKD3_k127_5805564_11 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.24e-268 828.0
HKD3_k127_5805564_12 GGDEF domain - - - 5.052e-247 797.0
HKD3_k127_5805564_13 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 2.861e-230 719.0
HKD3_k127_5805564_14 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 8.18e-227 708.0
HKD3_k127_5805564_15 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 4.642e-224 710.0
HKD3_k127_5805564_16 Involved in the biosynthesis of porphyrin-containing compound - - - 1.582e-221 695.0
HKD3_k127_5805564_17 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 1.13e-218 686.0
HKD3_k127_5805564_18 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 9.805e-213 668.0
HKD3_k127_5805564_19 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.566e-212 662.0
HKD3_k127_5805564_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1315.0
HKD3_k127_5805564_20 Cyclic nucleotide-binding domain - - - 4.529e-207 649.0
HKD3_k127_5805564_21 Pilus assembly protein K02662 - - 1.448e-203 636.0
HKD3_k127_5805564_22 receptor K16092 - - 3.989e-195 630.0
HKD3_k127_5805564_23 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 544.0
HKD3_k127_5805564_24 Belongs to the IUNH family K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 518.0
HKD3_k127_5805564_25 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 494.0
HKD3_k127_5805564_26 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 487.0
HKD3_k127_5805564_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 462.0
HKD3_k127_5805564_28 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 456.0
HKD3_k127_5805564_29 Zn-dependent hydrolases including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 451.0
HKD3_k127_5805564_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1275.0
HKD3_k127_5805564_30 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 443.0
HKD3_k127_5805564_31 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 426.0
HKD3_k127_5805564_32 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 376.0
HKD3_k127_5805564_33 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 362.0
HKD3_k127_5805564_34 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 340.0
HKD3_k127_5805564_35 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 331.0
HKD3_k127_5805564_36 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 319.0
HKD3_k127_5805564_37 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 302.0
HKD3_k127_5805564_38 Outer membrane protein W K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 297.0
HKD3_k127_5805564_39 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 261.0
HKD3_k127_5805564_4 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1258.0
HKD3_k127_5805564_40 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005205 265.0
HKD3_k127_5805564_41 assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009736 265.0
HKD3_k127_5805564_42 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002397 241.0
HKD3_k127_5805564_43 endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000004764 222.0
HKD3_k127_5805564_44 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000006272 231.0
HKD3_k127_5805564_45 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000466 203.0
HKD3_k127_5805564_46 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000004005 177.0
HKD3_k127_5805564_47 PilZ domain - - - 0.00000000000000000000000000000000000000000000001142 188.0
HKD3_k127_5805564_48 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001744 165.0
HKD3_k127_5805564_49 - - - - 0.0000000000000000000000000000000000000001152 171.0
HKD3_k127_5805564_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1178.0
HKD3_k127_5805564_50 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000001329 152.0
HKD3_k127_5805564_51 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000001406 149.0
HKD3_k127_5805564_52 Putative phosphatase (DUF442) - - - 0.000000000000000000000000000004371 126.0
HKD3_k127_5805564_53 transcriptional - - - 0.0000000000000000000000000001829 120.0
HKD3_k127_5805564_54 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000005035 112.0
HKD3_k127_5805564_55 Threonine/Serine exporter, ThrE - - - 0.000000000000000001406 85.0
HKD3_k127_5805564_56 Cysteine-rich CPXCG - - - 0.00000000000000001713 96.0
HKD3_k127_5805564_57 Domain of unknown function (DUF4124) - - - 0.0000000000000000654 86.0
HKD3_k127_5805564_58 Domain of unknown function (DUF4124) - - - 0.0000000000000002212 84.0
HKD3_k127_5805564_59 - - - - 0.00000000000004495 85.0
HKD3_k127_5805564_6 Type II secretory pathway, component HofQ K02666 - - 0.0 1073.0
HKD3_k127_5805564_7 peptidase K07386 - - 3e-323 1003.0
HKD3_k127_5805564_8 Protein of unknown function (DUF1631) - - - 2.238e-304 951.0
HKD3_k127_5805564_9 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.862e-300 928.0
HKD3_k127_6038084_0 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0 2788.0
HKD3_k127_6038084_1 MASE1 - - - 0.0 1033.0
HKD3_k127_6038084_10 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 581.0
HKD3_k127_6038084_11 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 578.0
HKD3_k127_6038084_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 526.0
HKD3_k127_6038084_13 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 495.0
HKD3_k127_6038084_14 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 430.0
HKD3_k127_6038084_15 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 404.0
HKD3_k127_6038084_16 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 408.0
HKD3_k127_6038084_17 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 383.0
HKD3_k127_6038084_18 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 362.0
HKD3_k127_6038084_19 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 341.0
HKD3_k127_6038084_2 Peptidase family M49 - - - 3.239e-308 951.0
HKD3_k127_6038084_20 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 342.0
HKD3_k127_6038084_21 COG4240 Predicted kinase K15918 - 2.7.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 344.0
HKD3_k127_6038084_22 chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 336.0
HKD3_k127_6038084_23 ABC transporter substrate-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 324.0
HKD3_k127_6038084_24 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 307.0
HKD3_k127_6038084_25 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 303.0
HKD3_k127_6038084_26 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 294.0
HKD3_k127_6038084_27 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 270.0
HKD3_k127_6038084_28 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005851 273.0
HKD3_k127_6038084_29 response regulator K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 252.0
HKD3_k127_6038084_3 chemotaxis protein K02660 - - 6.919e-284 886.0
HKD3_k127_6038084_30 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002616 239.0
HKD3_k127_6038084_31 Domain of unknown function (DUF4426) - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HKD3_k127_6038084_32 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
HKD3_k127_6038084_33 protein-glutamate methylesterase K06597 - - 0.00000000000000000000000000000000000000000000000000000000000009608 230.0
HKD3_k127_6038084_34 - - - - 0.00000000000000000000000000000000000005834 143.0
HKD3_k127_6038084_35 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000006838 140.0
HKD3_k127_6038084_36 Dodecin K09165 - - 0.0000000000000000000000007167 105.0
HKD3_k127_6038084_37 Glutaredoxin-like domain (DUF836) - - - 0.000000000000000000000001408 119.0
HKD3_k127_6038084_38 Histidine kinase - - - 0.00000000000004307 80.0
HKD3_k127_6038084_39 Histidine kinase - - - 0.000000004828 69.0
HKD3_k127_6038084_4 Serine dehydratase K01752 - 4.3.1.17 9.026e-275 862.0
HKD3_k127_6038084_5 twitching motility protein K02670 - - 1.182e-239 741.0
HKD3_k127_6038084_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.217e-223 699.0
HKD3_k127_6038084_7 twitching motility protein K02669 - - 1.166e-210 657.0
HKD3_k127_6038084_8 cystathionine K01739 - 2.5.1.48 7.265e-208 657.0
HKD3_k127_6038084_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 625.0
HKD3_k127_6048456_0 Part of a membrane complex involved in electron transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 577.0
HKD3_k127_6048456_1 Part of a membrane complex involved in electron transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 555.0
HKD3_k127_6048456_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 426.0
HKD3_k127_6048456_3 DNA mismatch repair protein MutT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
HKD3_k127_6048456_4 Peptidyl-prolyl cis-trans K01802,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 320.0
HKD3_k127_6048456_5 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 306.0
HKD3_k127_6048456_6 Protein of unknown function (DUF1289) - - - 0.0000000000000000000001099 101.0
HKD3_k127_6054697_0 decarboxylase - - - 2.371e-297 925.0
HKD3_k127_6077708_0 Putative diguanylate phosphodiesterase - - - 0.0 1075.0
HKD3_k127_6077708_1 Citrate transporter - - - 4.443e-248 772.0
HKD3_k127_6077708_2 phosphate transporter K03306 - - 4.611e-199 626.0
HKD3_k127_6077708_3 Hemolysins and related proteins containing CBS domains K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 515.0
HKD3_k127_6077708_4 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 466.0
HKD3_k127_6077708_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 371.0
HKD3_k127_6077708_6 Pit accessory protein K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 369.0
HKD3_k127_6077708_7 exopolysaccharide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
HKD3_k127_6077708_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000007683 70.0
HKD3_k127_6082736_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1417.0
HKD3_k127_6082736_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1382.0
HKD3_k127_6082736_10 Polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 563.0
HKD3_k127_6082736_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 513.0
HKD3_k127_6082736_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 513.0
HKD3_k127_6082736_13 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 498.0
HKD3_k127_6082736_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 495.0
HKD3_k127_6082736_15 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 493.0
HKD3_k127_6082736_16 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 516.0
HKD3_k127_6082736_17 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 485.0
HKD3_k127_6082736_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 453.0
HKD3_k127_6082736_19 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 408.0
HKD3_k127_6082736_2 Penicillin acylase K01434 - 3.5.1.11 0.0 1205.0
HKD3_k127_6082736_20 regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 401.0
HKD3_k127_6082736_21 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 402.0
HKD3_k127_6082736_22 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 395.0
HKD3_k127_6082736_23 acetyltransferase K06977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 363.0
HKD3_k127_6082736_24 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 342.0
HKD3_k127_6082736_25 membrane K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
HKD3_k127_6082736_26 Flavin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 293.0
HKD3_k127_6082736_27 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002693 270.0
HKD3_k127_6082736_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006334 257.0
HKD3_k127_6082736_29 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
HKD3_k127_6082736_3 ABC transporter transmembrane region K06147 - - 0.0 1015.0
HKD3_k127_6082736_30 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000005802 253.0
HKD3_k127_6082736_31 SMR domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004725 235.0
HKD3_k127_6082736_32 Serine hydrolase K07002,K19073 - 1.3.1.75 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
HKD3_k127_6082736_33 ArsC family - - - 0.0000000000000000000000000000000000000000000000000000000000001894 226.0
HKD3_k127_6082736_34 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001129 185.0
HKD3_k127_6082736_35 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000000000000000000000000000000000001746 156.0
HKD3_k127_6082736_4 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.401e-320 994.0
HKD3_k127_6082736_5 converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP K01953 - 6.3.5.4 5.057e-317 976.0
HKD3_k127_6082736_6 transport system involved in gliding motility, auxiliary component - - - 2.541e-269 841.0
HKD3_k127_6082736_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 5.798e-209 664.0
HKD3_k127_6082736_8 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 3.635e-203 639.0
HKD3_k127_6082736_9 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 597.0
HKD3_k127_6160008_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1088.0
HKD3_k127_6160008_1 esterase K12686 - - 1.563e-196 642.0
HKD3_k127_6160008_10 PFAM Spore coat protein U - - - 0.00000000000000000000000000000000000001312 158.0
HKD3_k127_6160008_11 Spore Coat Protein U domain - - - 0.000000000000000000000000000000000006328 144.0
HKD3_k127_6160008_2 outer membrane usher protein K07347 - - 5.341e-195 636.0
HKD3_k127_6160008_3 dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 479.0
HKD3_k127_6160008_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 463.0
HKD3_k127_6160008_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 458.0
HKD3_k127_6160008_6 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003374 267.0
HKD3_k127_6160008_7 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005475 222.0
HKD3_k127_6160008_8 Pilus assembly protein K07346 - - 0.0000000000000000000000000000000000000000000000000000007934 205.0
HKD3_k127_6160008_9 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000005923 188.0
HKD3_k127_6303680_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1508.0
HKD3_k127_6303680_1 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
HKD3_k127_6303680_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 485.0
HKD3_k127_6303680_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 419.0
HKD3_k127_6303680_4 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 373.0
HKD3_k127_6303680_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004241 226.0
HKD3_k127_6303680_6 Protein of unknown function (DUF465) - - - 0.00000000000000000000000001816 123.0
HKD3_k127_6563142_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.618e-267 838.0
HKD3_k127_6563142_1 glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 590.0
HKD3_k127_6563142_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000001249 175.0
HKD3_k127_6563142_11 ferredoxin - - - 0.00000000000000000000000000000000000000000001003 163.0
HKD3_k127_6563142_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 495.0
HKD3_k127_6563142_3 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 458.0
HKD3_k127_6563142_4 Repeat of Unknown Function (DUF347) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 344.0
HKD3_k127_6563142_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 306.0
HKD3_k127_6563142_6 metallo-beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000154 280.0
HKD3_k127_6563142_7 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003825 289.0
HKD3_k127_6563142_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000009647 220.0
HKD3_k127_6563142_9 - - - - 0.00000000000000000000000000000000000000000000000003977 184.0
HKD3_k127_6612258_0 ABC transporter K06147 - - 7.101e-277 873.0
HKD3_k127_6612258_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 3.102e-239 744.0
HKD3_k127_6612258_10 Uncharacterized protein family UPF0029 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HKD3_k127_6612258_11 CYTH domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000199 264.0
HKD3_k127_6612258_12 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001143 272.0
HKD3_k127_6612258_13 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
HKD3_k127_6612258_14 Cold shock protein domain - - - 0.000000000000000000000000000000000001235 138.0
HKD3_k127_6612258_15 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000002044 116.0
HKD3_k127_6612258_2 Protein conserved in bacteria - - - 2.719e-197 623.0
HKD3_k127_6612258_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 572.0
HKD3_k127_6612258_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 507.0
HKD3_k127_6612258_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 429.0
HKD3_k127_6612258_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 351.0
HKD3_k127_6612258_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 320.0
HKD3_k127_6612258_8 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 300.0
HKD3_k127_6612258_9 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 299.0
HKD3_k127_6623255_0 Cystathionine beta-synthase K01697 - 4.2.1.22 5.768e-278 857.0
HKD3_k127_6623255_1 Transporter K03305 - - 2.39e-266 830.0
HKD3_k127_6623255_10 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001011 235.0
HKD3_k127_6623255_11 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000154 140.0
HKD3_k127_6623255_12 Protein of unknown function (DUF465) - - - 0.00000000000000000000000000000006386 125.0
HKD3_k127_6623255_13 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000007807 118.0
HKD3_k127_6623255_2 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 1.899e-244 760.0
HKD3_k127_6623255_3 twitching motility protein K02670 - - 3.063e-231 718.0
HKD3_k127_6623255_4 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 3.118e-213 665.0
HKD3_k127_6623255_5 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009562 588.0
HKD3_k127_6623255_6 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 474.0
HKD3_k127_6623255_7 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
HKD3_k127_6623255_8 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008079 289.0
HKD3_k127_6623255_9 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008048 242.0
HKD3_k127_6709274_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1695.0
HKD3_k127_6709274_1 peptidase K01354 - 3.4.21.83 0.0 1146.0
HKD3_k127_6709274_10 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.523e-263 858.0
HKD3_k127_6709274_11 Protein of unknown function (DUF1800) - - - 1.082e-256 806.0
HKD3_k127_6709274_12 Type II secretion system (T2SS), protein E, N-terminal domain - - - 8.432e-246 771.0
HKD3_k127_6709274_13 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 595.0
HKD3_k127_6709274_14 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 584.0
HKD3_k127_6709274_15 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 557.0
HKD3_k127_6709274_16 Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 527.0
HKD3_k127_6709274_17 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 524.0
HKD3_k127_6709274_18 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 513.0
HKD3_k127_6709274_19 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 489.0
HKD3_k127_6709274_2 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0 1112.0
HKD3_k127_6709274_20 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 489.0
HKD3_k127_6709274_21 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 480.0
HKD3_k127_6709274_22 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 473.0
HKD3_k127_6709274_23 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 467.0
HKD3_k127_6709274_24 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 448.0
HKD3_k127_6709274_25 4Fe-4S dicluster domain K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 448.0
HKD3_k127_6709274_26 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 405.0
HKD3_k127_6709274_27 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 440.0
HKD3_k127_6709274_28 Response regulator of the LytR AlgR family K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 394.0
HKD3_k127_6709274_29 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 372.0
HKD3_k127_6709274_3 aminopeptidase - - - 0.0 1094.0
HKD3_k127_6709274_30 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 376.0
HKD3_k127_6709274_31 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 361.0
HKD3_k127_6709274_32 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 360.0
HKD3_k127_6709274_33 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 361.0
HKD3_k127_6709274_34 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 353.0
HKD3_k127_6709274_35 DMSO reductase anchor subunit (DmsC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 335.0
HKD3_k127_6709274_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 304.0
HKD3_k127_6709274_37 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 298.0
HKD3_k127_6709274_38 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001257 248.0
HKD3_k127_6709274_39 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000003067 215.0
HKD3_k127_6709274_4 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.0 1052.0
HKD3_k127_6709274_40 - - - - 0.0000000000000000000000000000000000000000000000007824 178.0
HKD3_k127_6709274_41 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000001229 143.0
HKD3_k127_6709274_42 - - - - 0.000000000000000000000000000000001382 140.0
HKD3_k127_6709274_44 FixH K09926 - - 0.000000000000000000000000313 122.0
HKD3_k127_6709274_45 - - - - 0.00000000000000000001843 93.0
HKD3_k127_6709274_46 LytTr DNA-binding domain - - - 0.0000000000000003822 81.0
HKD3_k127_6709274_47 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000000001194 75.0
HKD3_k127_6709274_48 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000002284 81.0
HKD3_k127_6709274_49 - - - - 0.00000006814 63.0
HKD3_k127_6709274_5 lysine biosynthetic process via aminoadipic acid - - - 0.0 1049.0
HKD3_k127_6709274_6 aminopeptidase - - - 4.378e-280 869.0
HKD3_k127_6709274_7 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.153e-274 848.0
HKD3_k127_6709274_8 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.359e-267 826.0
HKD3_k127_6709274_9 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 2.538e-266 829.0
HKD3_k127_6927764_0 Glutaryl-7-ACA acylase K06978 - - 0.0 1110.0
HKD3_k127_6927764_1 Pyridoxal-dependent decarboxylase conserved domain - - - 2.438e-212 669.0
HKD3_k127_6927764_10 pseudouridine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 361.0
HKD3_k127_6927764_11 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 350.0
HKD3_k127_6927764_12 Protein of unknown function (DUF3228) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 347.0
HKD3_k127_6927764_13 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 300.0
HKD3_k127_6927764_14 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 294.0
HKD3_k127_6927764_15 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002482 299.0
HKD3_k127_6927764_16 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 278.0
HKD3_k127_6927764_17 LemA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
HKD3_k127_6927764_18 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000275 263.0
HKD3_k127_6927764_19 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000003245 193.0
HKD3_k127_6927764_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 603.0
HKD3_k127_6927764_20 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000005515 170.0
HKD3_k127_6927764_21 YCII-related domain - - - 0.00000000000000000000000000000000000000000001174 176.0
HKD3_k127_6927764_22 TIGRFAM phage conjugal plasmid C-4 type zinc finger protein, TraR family - - - 0.00000000000000000000000000000000000000001253 154.0
HKD3_k127_6927764_23 - - - - 0.00000000000000000000000000000000000000002038 166.0
HKD3_k127_6927764_24 - - - - 0.00000000000000000000000000000001983 138.0
HKD3_k127_6927764_25 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000368 102.0
HKD3_k127_6927764_26 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000009511 81.0
HKD3_k127_6927764_3 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 597.0
HKD3_k127_6927764_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 430.0
HKD3_k127_6927764_5 MASE2 domain K18968 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 428.0
HKD3_k127_6927764_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 394.0
HKD3_k127_6927764_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 395.0
HKD3_k127_6927764_8 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 388.0
HKD3_k127_6927764_9 Domain of unknown function (DUF4932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 385.0
HKD3_k127_6958259_0 Predicted membrane protein (DUF2339) - - - 0.0 1057.0
HKD3_k127_6958259_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 4.121e-282 869.0
HKD3_k127_6958259_10 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 561.0
HKD3_k127_6958259_11 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 544.0
HKD3_k127_6958259_12 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 539.0
HKD3_k127_6958259_13 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K07823 - 2.3.1.174 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 483.0
HKD3_k127_6958259_14 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 491.0
HKD3_k127_6958259_15 Spermidine putrescine ABC transporter permease K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 451.0
HKD3_k127_6958259_16 Protein of unknown function (DUF3999) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 452.0
HKD3_k127_6958259_17 Glutamine K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 412.0
HKD3_k127_6958259_18 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 395.0
HKD3_k127_6958259_19 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 404.0
HKD3_k127_6958259_2 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 9.917e-282 875.0
HKD3_k127_6958259_20 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 385.0
HKD3_k127_6958259_21 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 371.0
HKD3_k127_6958259_22 Phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 323.0
HKD3_k127_6958259_23 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 328.0
HKD3_k127_6958259_24 Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate K22292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 324.0
HKD3_k127_6958259_25 methyltransferase activity - - - 0.0000000000000000000000000000000000002473 147.0
HKD3_k127_6958259_26 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000003296 127.0
HKD3_k127_6958259_3 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 5.157e-281 866.0
HKD3_k127_6958259_4 Amidohydrolase family - - - 6.827e-260 807.0
HKD3_k127_6958259_5 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 9.038e-257 796.0
HKD3_k127_6958259_6 Oxidoreductase K09471 - - 5.162e-236 734.0
HKD3_k127_6958259_7 Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline K12960 - 3.5.4.28,3.5.4.31 1.552e-232 725.0
HKD3_k127_6958259_8 COG2202 FOG PAS PAC domain K21025 - - 2.492e-220 689.0
HKD3_k127_6958259_9 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 1.286e-197 622.0
HKD3_k127_7051050_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 0.0 1401.0
HKD3_k127_7051050_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 382.0
HKD3_k127_7051050_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000000000000009276 207.0
HKD3_k127_7051050_3 - - - - 0.0000000000000000000000000000000000000000004808 164.0
HKD3_k127_7051050_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000015 151.0
HKD3_k127_7051050_5 protein conserved in bacteria K09919 - - 0.00000000000000000000000000002665 119.0
HKD3_k127_7051050_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000005422 86.0
HKD3_k127_7092851_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1215.0
HKD3_k127_7092851_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 295.0
HKD3_k127_7092851_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
HKD3_k127_7253247_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1793.0
HKD3_k127_7253247_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1215.0
HKD3_k127_7253247_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 4.777e-208 653.0
HKD3_k127_7253247_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 4.464e-201 630.0
HKD3_k127_7253247_12 Sugar kinase K00856 - 2.7.1.20 2.148e-194 612.0
HKD3_k127_7253247_13 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 586.0
HKD3_k127_7253247_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 559.0
HKD3_k127_7253247_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 534.0
HKD3_k127_7253247_16 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 514.0
HKD3_k127_7253247_17 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 466.0
HKD3_k127_7253247_18 murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 467.0
HKD3_k127_7253247_19 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 454.0
HKD3_k127_7253247_2 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 0.0 1119.0
HKD3_k127_7253247_20 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 452.0
HKD3_k127_7253247_21 Methyltransferase K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 419.0
HKD3_k127_7253247_22 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 411.0
HKD3_k127_7253247_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 413.0
HKD3_k127_7253247_24 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 411.0
HKD3_k127_7253247_25 Hydrolase K20862 - 3.1.3.102,3.1.3.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 384.0
HKD3_k127_7253247_26 Predicted membrane protein (DUF2306) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 376.0
HKD3_k127_7253247_27 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 386.0
HKD3_k127_7253247_28 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 365.0
HKD3_k127_7253247_29 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004223 273.0
HKD3_k127_7253247_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1017.0
HKD3_k127_7253247_30 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
HKD3_k127_7253247_31 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000000000000000000000008306 228.0
HKD3_k127_7253247_32 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000001212 204.0
HKD3_k127_7253247_33 MAPEG family - - - 0.0000000000000000000000000000000000000000000002634 170.0
HKD3_k127_7253247_34 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000000000000001096 157.0
HKD3_k127_7253247_35 heparin binding - - - 0.000000000000000000000009654 114.0
HKD3_k127_7253247_36 - - - - 0.0000000546 55.0
HKD3_k127_7253247_4 Belongs to the peptidase M17 family K01255 - 3.4.11.1 2.847e-248 784.0
HKD3_k127_7253247_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 4.824e-238 746.0
HKD3_k127_7253247_6 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.365e-229 715.0
HKD3_k127_7253247_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 1.963e-214 670.0
HKD3_k127_7253247_8 Rod shape-determining protein K03569 - - 5.134e-212 660.0
HKD3_k127_7253247_9 cAMP biosynthetic process - - - 2.284e-210 677.0
HKD3_k127_7367731_0 Pathogenicity protein K09800 - - 0.0 1255.0
HKD3_k127_7367731_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 8.853e-305 949.0
HKD3_k127_7367731_11 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000004979 125.0
HKD3_k127_7367731_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000002258 126.0
HKD3_k127_7367731_13 protein secretion K03116,K03425 GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000002189 83.0
HKD3_k127_7367731_2 membrane K07278 - - 4.053e-219 693.0
HKD3_k127_7367731_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 601.0
HKD3_k127_7367731_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 572.0
HKD3_k127_7367731_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 421.0
HKD3_k127_7367731_6 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 391.0
HKD3_k127_7367731_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 347.0
HKD3_k127_7367731_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 324.0
HKD3_k127_7367731_9 RDD family - - - 0.00000000000000000000000000000000000000000000000366 191.0
HKD3_k127_7370959_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.0 2145.0
HKD3_k127_7370959_1 Histidine Phosphotransfer domain - - - 0.0 1434.0
HKD3_k127_7370959_10 ATPase family associated with various cellular activities (AAA) - - - 5.603e-278 863.0
HKD3_k127_7370959_11 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 3.943e-236 735.0
HKD3_k127_7370959_12 Oxidoreductase K06969 - 2.1.1.191 1.01e-225 701.0
HKD3_k127_7370959_13 Putative diguanylate phosphodiesterase - - - 5.995e-212 668.0
HKD3_k127_7370959_14 Putative diguanylate phosphodiesterase - - - 4.035e-209 656.0
HKD3_k127_7370959_15 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 4.47e-201 636.0
HKD3_k127_7370959_16 synthase K22317 - - 1.168e-200 627.0
HKD3_k127_7370959_17 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 605.0
HKD3_k127_7370959_18 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 600.0
HKD3_k127_7370959_19 Major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 581.0
HKD3_k127_7370959_2 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0 1258.0
HKD3_k127_7370959_20 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 582.0
HKD3_k127_7370959_21 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 559.0
HKD3_k127_7370959_22 3-beta hydroxysteroid dehydrogenase K22320 - 1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 523.0
HKD3_k127_7370959_23 porphyrin biosynthesis protein K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 513.0
HKD3_k127_7370959_24 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 488.0
HKD3_k127_7370959_25 Alpha beta hydrolase K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 496.0
HKD3_k127_7370959_26 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 438.0
HKD3_k127_7370959_27 acetyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 421.0
HKD3_k127_7370959_28 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 397.0
HKD3_k127_7370959_29 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 393.0
HKD3_k127_7370959_3 Peptidase M16 - - - 0.0 1135.0
HKD3_k127_7370959_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 391.0
HKD3_k127_7370959_31 pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 383.0
HKD3_k127_7370959_32 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 370.0
HKD3_k127_7370959_33 CMP-binding protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 370.0
HKD3_k127_7370959_34 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 360.0
HKD3_k127_7370959_35 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 346.0
HKD3_k127_7370959_36 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 350.0
HKD3_k127_7370959_37 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 335.0
HKD3_k127_7370959_38 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 329.0
HKD3_k127_7370959_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 327.0
HKD3_k127_7370959_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1060.0
HKD3_k127_7370959_40 Sterol-binding protein K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 324.0
HKD3_k127_7370959_41 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 313.0
HKD3_k127_7370959_42 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 302.0
HKD3_k127_7370959_43 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 300.0
HKD3_k127_7370959_44 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 318.0
HKD3_k127_7370959_45 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
HKD3_k127_7370959_46 phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001946 261.0
HKD3_k127_7370959_47 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000001054 230.0
HKD3_k127_7370959_48 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000007884 235.0
HKD3_k127_7370959_49 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000001283 226.0
HKD3_k127_7370959_5 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 4.594e-294 904.0
HKD3_k127_7370959_51 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000001524 230.0
HKD3_k127_7370959_52 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000001468 213.0
HKD3_k127_7370959_53 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
HKD3_k127_7370959_54 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000004509 205.0
HKD3_k127_7370959_55 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000007336 198.0
HKD3_k127_7370959_56 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000161 196.0
HKD3_k127_7370959_57 Domain of unknown function (DUF4156) - - - 0.0000000000000000000000000000000000000000000000001173 181.0
HKD3_k127_7370959_58 thioesterase - - - 0.00000000000000000000000000000000000000000000003956 181.0
HKD3_k127_7370959_59 - - - - 0.00000000000000000000000000000000000000000001206 170.0
HKD3_k127_7370959_6 Peptide synthase K22319 - 6.1.3.1 6.34e-286 890.0
HKD3_k127_7370959_60 - - - - 0.0000000000000000000000000000000000000000002578 162.0
HKD3_k127_7370959_61 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000009284 139.0
HKD3_k127_7370959_62 - - - - 0.000000000000000000000000000003437 127.0
HKD3_k127_7370959_63 - - - - 0.00000000000000000000003391 103.0
HKD3_k127_7370959_64 - - - - 0.000000002693 62.0
HKD3_k127_7370959_7 Cardiolipin synthase - - - 1.017e-281 876.0
HKD3_k127_7370959_8 Putative diguanylate phosphodiesterase - - - 1.089e-280 893.0
HKD3_k127_7370959_9 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.442e-280 902.0
HKD3_k127_7377708_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 571.0
HKD3_k127_7377708_1 Transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 507.0
HKD3_k127_7377708_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 286.0
HKD3_k127_7377708_3 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000001199 91.0
HKD3_k127_7499495_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.0 1514.0
HKD3_k127_7499495_1 peptidase K07386 - - 0.0 1084.0
HKD3_k127_7499495_10 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 402.0
HKD3_k127_7499495_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 385.0
HKD3_k127_7499495_12 Belongs to the phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 365.0
HKD3_k127_7499495_13 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 340.0
HKD3_k127_7499495_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 342.0
HKD3_k127_7499495_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 305.0
HKD3_k127_7499495_16 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 294.0
HKD3_k127_7499495_17 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
HKD3_k127_7499495_18 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001085 266.0
HKD3_k127_7499495_19 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 257.0
HKD3_k127_7499495_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 5.58e-295 911.0
HKD3_k127_7499495_20 MerC mercury resistance protein - - - 0.000000000000000000000000000000000000000000000000000002693 203.0
HKD3_k127_7499495_21 Domain of unknown function (DUF4399) - - - 0.00000000000000000000000000000000000000000000001045 188.0
HKD3_k127_7499495_22 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000000000000000000000000000000005749 169.0
HKD3_k127_7499495_24 membrane - - - 0.00000000000002551 72.0
HKD3_k127_7499495_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.257e-288 889.0
HKD3_k127_7499495_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.749e-255 792.0
HKD3_k127_7499495_5 Peptidase, M13 K07386 - - 3.834e-222 707.0
HKD3_k127_7499495_6 CoA-transferase family III - - - 1.683e-209 665.0
HKD3_k127_7499495_7 deiminase K05603 - 3.5.3.13 2.917e-198 623.0
HKD3_k127_7499495_8 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
HKD3_k127_7499495_9 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 596.0
HKD3_k127_7611908_0 peptidase - - - 0.0 1153.0
HKD3_k127_7611908_1 transporter - - - 0.0 1019.0
HKD3_k127_7611908_2 Transporter K03305 - - 1.04e-298 928.0
HKD3_k127_7611908_3 transport protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 593.0
HKD3_k127_7611908_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 411.0
HKD3_k127_7611908_5 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000001676 179.0
HKD3_k127_7622142_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 589.0
HKD3_k127_7622142_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 322.0
HKD3_k127_7622142_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000001907 154.0
HKD3_k127_7622142_3 - - - - 0.00000000000000000001162 96.0
HKD3_k127_7651052_0 Diguanylate cyclase - - - 0.0 1098.0
HKD3_k127_7651052_1 Bacterial protein of unknown function (DUF885) - - - 1.727e-300 930.0
HKD3_k127_7651052_2 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 597.0
HKD3_k127_7651052_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 568.0
HKD3_k127_7651052_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 519.0
HKD3_k127_7651052_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 415.0
HKD3_k127_7651052_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
HKD3_k127_7651052_7 two-component system K02485 - - 0.00000000000000000000000000000000000000000000000000000000000006538 230.0
HKD3_k127_7651052_8 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000501 127.0
HKD3_k127_766306_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 4.524e-307 945.0
HKD3_k127_766306_1 Peptidase M48 Ste24p - - - 3.526e-296 923.0
HKD3_k127_766306_10 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 477.0
HKD3_k127_766306_11 PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 428.0
HKD3_k127_766306_12 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 406.0
HKD3_k127_766306_13 Major Facilitator Superfamily K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 390.0
HKD3_k127_766306_14 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 373.0
HKD3_k127_766306_15 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 324.0
HKD3_k127_766306_16 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 321.0
HKD3_k127_766306_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
HKD3_k127_766306_18 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 246.0
HKD3_k127_766306_19 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000001073 230.0
HKD3_k127_766306_2 Autotransporter beta-domain - - - 5.74e-272 884.0
HKD3_k127_766306_20 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000000000000000000000001659 204.0
HKD3_k127_766306_21 - - - - 0.0000000000000000000000000000000000000000004365 166.0
HKD3_k127_766306_22 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000006134 177.0
HKD3_k127_766306_23 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000001063 156.0
HKD3_k127_766306_24 Family of unknown function (DUF5329) - - - 0.0000000000000000000000000001222 121.0
HKD3_k127_766306_25 Copper homeostasis K06079 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0010810,GO:0016020,GO:0019867,GO:0030155,GO:0030312,GO:0030313,GO:0031975,GO:0042802,GO:0044462,GO:0044464,GO:0050789,GO:0065007,GO:0071944 - 0.0000000000000000000000000018 125.0
HKD3_k127_766306_26 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000001982 88.0
HKD3_k127_766306_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 7.035e-246 763.0
HKD3_k127_766306_4 Na dependent nucleoside transporter K03317 - - 2.51e-221 693.0
HKD3_k127_766306_5 Thermolysin metallopeptidase, catalytic domain - - - 1.213e-209 668.0
HKD3_k127_766306_6 beta-lactamase K01467 - 3.5.2.6 6.027e-208 656.0
HKD3_k127_766306_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 3.368e-206 644.0
HKD3_k127_766306_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 561.0
HKD3_k127_766306_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 521.0
HKD3_k127_7792185_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1055.0
HKD3_k127_7792185_1 Protein of unknown function, DUF255 - - - 2.73e-303 966.0
HKD3_k127_7792185_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 488.0
HKD3_k127_7792185_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 490.0
HKD3_k127_7792185_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 448.0
HKD3_k127_7792185_13 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 432.0
HKD3_k127_7792185_14 acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 401.0
HKD3_k127_7792185_15 membrane protein terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 398.0
HKD3_k127_7792185_16 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 350.0
HKD3_k127_7792185_17 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 328.0
HKD3_k127_7792185_18 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
HKD3_k127_7792185_19 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008636 254.0
HKD3_k127_7792185_2 Histidine kinase - - - 3.778e-231 722.0
HKD3_k127_7792185_20 protein affecting Mg2 Co2 transport K06195 - - 0.000000000000000000000000000000000000000000000000000000000000000001627 228.0
HKD3_k127_7792185_21 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
HKD3_k127_7792185_22 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000000000000186 231.0
HKD3_k127_7792185_23 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000001262 220.0
HKD3_k127_7792185_24 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000114 97.0
HKD3_k127_7792185_3 Oxidoreductase - - - 2.651e-209 662.0
HKD3_k127_7792185_4 MacB-like periplasmic core domain K02004 - - 5.782e-207 662.0
HKD3_k127_7792185_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 609.0
HKD3_k127_7792185_6 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 551.0
HKD3_k127_7792185_7 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 541.0
HKD3_k127_7792185_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 538.0
HKD3_k127_7792185_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 535.0
HKD3_k127_7821667_0 AbgT putative transporter family - - - 2.111e-211 670.0
HKD3_k127_7821667_1 Protein of unknown function (DUF1298) - - - 3.004e-211 679.0
HKD3_k127_7821667_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 251.0
HKD3_k127_7821667_3 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000001289 196.0
HKD3_k127_7821667_4 PIN domain - - - 0.00000000000000000000000000000000000000000000005168 176.0
HKD3_k127_7821667_5 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000002295 100.0
HKD3_k127_7822446_0 Peptidase family S58 - - - 6.55e-199 629.0
HKD3_k127_7822446_1 amino acid K03294,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 466.0
HKD3_k127_7822446_2 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 388.0
HKD3_k127_7822446_3 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.0000000000000000000000000000000000000000000000000000006773 210.0
HKD3_k127_8151466_0 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 4.78e-243 754.0
HKD3_k127_8151466_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
HKD3_k127_8151466_2 SCO1/SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 240.0
HKD3_k127_8151466_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000008688 227.0
HKD3_k127_8151466_4 - - - - 0.00000000000000000000000000000000000000000000000001342 195.0
HKD3_k127_8151466_5 - - - - 0.0000000000000000002721 91.0
HKD3_k127_8294247_0 Outer membrane receptor - - - 0.0 1076.0
HKD3_k127_8294247_1 COG0457 FOG TPR repeat - - - 2.594e-289 904.0
HKD3_k127_8294247_10 Extradiol ring-cleavage dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 453.0
HKD3_k127_8294247_11 PFAM ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 442.0
HKD3_k127_8294247_12 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 430.0
HKD3_k127_8294247_13 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 347.0
HKD3_k127_8294247_14 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 353.0
HKD3_k127_8294247_15 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 314.0
HKD3_k127_8294247_16 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
HKD3_k127_8294247_17 protein conserved in bacteria K09941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006135 291.0
HKD3_k127_8294247_18 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003514 278.0
HKD3_k127_8294247_19 Peroxiredoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000003337 255.0
HKD3_k127_8294247_2 Bacterial protein of unknown function (DUF885) - - - 4.898e-263 825.0
HKD3_k127_8294247_20 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001481 257.0
HKD3_k127_8294247_21 cheY-homologous receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000000000002943 233.0
HKD3_k127_8294247_22 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000000000000000000000008251 190.0
HKD3_k127_8294247_23 - - - - 0.000000000000000000000000000000000000000000000000002008 190.0
HKD3_k127_8294247_24 - - - - 0.0000000000000000000000000000000000000000000000001036 186.0
HKD3_k127_8294247_25 MAPEG family - - - 0.00000000000000000000000000000000000000000000003308 173.0
HKD3_k127_8294247_26 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000003851 154.0
HKD3_k127_8294247_27 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000000000001886 123.0
HKD3_k127_8294247_28 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0000000000000000000000001664 107.0
HKD3_k127_8294247_29 pyridoxamine 5-phosphate - - - 0.000000000000000000000000257 121.0
HKD3_k127_8294247_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 3.114e-239 746.0
HKD3_k127_8294247_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 2.426e-237 738.0
HKD3_k127_8294247_5 HI0933-like protein K07007 - - 3.632e-217 679.0
HKD3_k127_8294247_6 phosphate-selective porin O and P - - - 1.826e-212 670.0
HKD3_k127_8294247_7 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 533.0
HKD3_k127_8294247_8 Zinc-uptake complex component A periplasmic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 491.0
HKD3_k127_8294247_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 505.0
HKD3_k127_8371761_0 General secretion pathway protein K02453 - - 0.0 1038.0
HKD3_k127_8371761_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 457.0
HKD3_k127_8371761_2 abc transporter atp-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 439.0
HKD3_k127_8371761_3 Glycosyl transferase K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 433.0
HKD3_k127_8371761_4 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 336.0
HKD3_k127_8371761_5 General secretion pathway protein K02462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005817 259.0
HKD3_k127_8371761_6 General secretion pathway protein K02463 - - 0.00000000000000000000000000000000000000000000000000002488 196.0
HKD3_k127_8371761_7 General secretion pathway protein K02461 - - 0.0000000000000000000000000000000003844 133.0
HKD3_k127_8449103_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.556e-248 770.0
HKD3_k127_8449103_1 abc transporter atp-binding protein - - - 1.077e-227 707.0
HKD3_k127_8449103_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 304.0
HKD3_k127_8449103_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001231 174.0
HKD3_k127_8486394_0 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 2.153e-294 911.0
HKD3_k127_8486394_1 Methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.502e-281 870.0
HKD3_k127_8486394_10 Belongs to the arginase family K01479,K01480 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 549.0
HKD3_k127_8486394_11 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 413.0
HKD3_k127_8486394_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 403.0
HKD3_k127_8486394_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 346.0
HKD3_k127_8486394_14 Phage-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 340.0
HKD3_k127_8486394_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 347.0
HKD3_k127_8486394_16 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
HKD3_k127_8486394_17 SufE protein probably involved in Fe-S center assembly K02426 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003404 250.0
HKD3_k127_8486394_18 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000004282 231.0
HKD3_k127_8486394_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001298 229.0
HKD3_k127_8486394_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.171e-278 862.0
HKD3_k127_8486394_20 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000001718 228.0
HKD3_k127_8486394_21 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000004388 92.0
HKD3_k127_8486394_3 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 1.481e-265 825.0
HKD3_k127_8486394_4 Protein of unknown function (DUF1298) - - - 7.279e-262 813.0
HKD3_k127_8486394_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 2.116e-261 809.0
HKD3_k127_8486394_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.346e-246 766.0
HKD3_k127_8486394_7 Belongs to the DNA photolyase family K01669 - 4.1.99.3 2.021e-223 734.0
HKD3_k127_8486394_8 alanine dehydrogenase K00259 - 1.4.1.1 3.875e-221 689.0
HKD3_k127_8486394_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - - 9.327e-212 664.0
HKD3_k127_8488469_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0 1034.0
HKD3_k127_8488469_1 Insulinase (Peptidase family M16) - - - 1.276e-244 766.0
HKD3_k127_8488469_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 3.904e-220 692.0
HKD3_k127_8488469_3 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 561.0
HKD3_k127_8488469_4 Thermolysin metallopeptidase, catalytic domain K20273 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 286.0
HKD3_k127_8488469_5 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001486 275.0
HKD3_k127_8488469_6 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 261.0
HKD3_k127_8488469_7 membrane K08973 - - 0.000000000000000000000000000000000000000000000000000000000000000001586 231.0
HKD3_k127_8488469_8 - - - - 0.0000000000000000000000000000000002866 145.0
HKD3_k127_8595701_0 Putative diguanylate phosphodiesterase - - - 0.0 1228.0
HKD3_k127_8595701_1 carboxylase K01968 - 6.4.1.4 0.0 1032.0
HKD3_k127_8595701_10 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009358 256.0
HKD3_k127_8595701_11 - - - - 0.000000000000000000000000000000000000000000001222 175.0
HKD3_k127_8595701_13 Cupredoxin-like domain - - - 0.0000000000000000000000000000000003074 134.0
HKD3_k127_8595701_14 FeoA - - - 0.000000000000000000000000000003241 123.0
HKD3_k127_8595701_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001485 113.0
HKD3_k127_8595701_2 Ferrous iron transport protein B K04759 - - 3.679e-238 741.0
HKD3_k127_8595701_3 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 508.0
HKD3_k127_8595701_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 437.0
HKD3_k127_8595701_5 enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 399.0
HKD3_k127_8595701_6 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 345.0
HKD3_k127_8595701_7 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 307.0
HKD3_k127_8595701_8 High-affinity Fe2 Pb2 permease K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 290.0
HKD3_k127_8595701_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 262.0
HKD3_k127_8688229_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 590.0
HKD3_k127_8688229_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001907 303.0
HKD3_k127_8688229_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000003038 241.0
HKD3_k127_8688229_3 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.00000000000000000000000000000000000000003306 158.0
HKD3_k127_8688229_6 serine-type endopeptidase activity K08372 - - 0.000000000000004497 89.0
HKD3_k127_8698354_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 333.0
HKD3_k127_8698354_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000001395 239.0
HKD3_k127_8707698_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 2.566e-289 894.0
HKD3_k127_8707698_1 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 8.588e-276 852.0
HKD3_k127_8707698_10 Spermidine putrescine ABC transporter permease K02053,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 484.0
HKD3_k127_8707698_11 Domain of unknown function (DUF4785) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 453.0
HKD3_k127_8707698_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 416.0
HKD3_k127_8707698_13 Formamidopyrimidine-DNA glycosylase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 407.0
HKD3_k127_8707698_14 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 398.0
HKD3_k127_8707698_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 347.0
HKD3_k127_8707698_16 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 327.0
HKD3_k127_8707698_17 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 311.0
HKD3_k127_8707698_18 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004664 253.0
HKD3_k127_8707698_19 translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000007357 249.0
HKD3_k127_8707698_2 Belongs to the aldehyde dehydrogenase family K07248 - 1.2.1.21,1.2.1.22 7.789e-272 855.0
HKD3_k127_8707698_20 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
HKD3_k127_8707698_21 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
HKD3_k127_8707698_22 - - - - 0.0000000000000000000000000000000000000000000004097 169.0
HKD3_k127_8707698_23 - - - - 0.00000000000000000000000000000000000000000004217 161.0
HKD3_k127_8707698_24 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002357 153.0
HKD3_k127_8707698_25 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000004237 140.0
HKD3_k127_8707698_3 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates K01141 - 3.1.11.1 1.109e-252 789.0
HKD3_k127_8707698_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 1.145e-245 762.0
HKD3_k127_8707698_5 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 3.889e-234 731.0
HKD3_k127_8707698_6 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 1.055e-213 664.0
HKD3_k127_8707698_7 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 591.0
HKD3_k127_8707698_8 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 578.0
HKD3_k127_8707698_9 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 493.0
HKD3_k127_8765353_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1115.0
HKD3_k127_8765353_1 desaturase K00507 - 1.14.19.1 1.321e-205 644.0
HKD3_k127_8765353_2 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 608.0
HKD3_k127_8765353_3 NAD dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 529.0
HKD3_k127_8765353_4 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 417.0
HKD3_k127_8765353_5 membrane - - - 0.000000000000000000000000000000000000000000000000000000006121 214.0
HKD3_k127_8765353_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000342 143.0
HKD3_k127_8765353_7 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000008284 109.0
HKD3_k127_8791155_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1754.0
HKD3_k127_8791155_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1400.0
HKD3_k127_8791155_10 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 317.0
HKD3_k127_8791155_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 295.0
HKD3_k127_8791155_12 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 291.0
HKD3_k127_8791155_13 Putative DNA-binding domain K09929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD3_k127_8791155_14 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000009733 254.0
HKD3_k127_8791155_15 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000355 250.0
HKD3_k127_8791155_16 EF hand - - - 0.00000000000000000000000000000003069 132.0
HKD3_k127_8791155_17 - - - - 0.0000000000000000000000005139 117.0
HKD3_k127_8791155_18 Outer membrane receptor - - - 0.000000000000000002027 92.0
HKD3_k127_8791155_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1305.0
HKD3_k127_8791155_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 6.67e-204 644.0
HKD3_k127_8791155_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 588.0
HKD3_k127_8791155_5 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 472.0
HKD3_k127_8791155_6 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 436.0
HKD3_k127_8791155_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 372.0
HKD3_k127_8791155_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 363.0
HKD3_k127_8791155_9 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 344.0
HKD3_k127_8888224_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 611.0
HKD3_k127_8888224_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 521.0
HKD3_k127_8888224_2 protein conserved in bacteria containing a pentein-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 422.0
HKD3_k127_8888224_3 Bacterial regulatory proteins, tetR family - - - 0.00007302 46.0
HKD3_k127_906932_0 PAS fold - - - 0.0 1223.0
HKD3_k127_906932_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 2.474e-210 661.0
HKD3_k127_906932_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 590.0
HKD3_k127_906932_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 517.0
HKD3_k127_906932_4 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000001571 239.0
HKD3_k127_906932_5 - - - - 0.00000000000000000000000000000000009428 135.0
HKD3_k127_906932_6 Competence protein - - - 0.00000000000000000000000000000007637 131.0
HKD3_k127_906932_8 Domain of unknown function (DUF4410) - - - 0.00004461 53.0
HKD3_k127_9241161_0 COG3459 Cellobiose phosphorylase - - - 0.0 3606.0
HKD3_k127_9241161_1 glutamate dehydrogenase K15371 - 1.4.1.2 0.0 2868.0
HKD3_k127_9241161_10 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.882e-250 779.0
HKD3_k127_9241161_11 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 4.381e-247 770.0
HKD3_k127_9241161_12 acyl-CoA dehydrogenase - - - 3.326e-242 750.0
HKD3_k127_9241161_13 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 1.656e-226 705.0
HKD3_k127_9241161_14 transcriptional regulator K18850 - 1.14.11.47 1.374e-214 672.0
HKD3_k127_9241161_15 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 1.624e-213 668.0
HKD3_k127_9241161_16 ABC transporter (Permease K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 559.0
HKD3_k127_9241161_17 ArsR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 550.0
HKD3_k127_9241161_18 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 542.0
HKD3_k127_9241161_19 Quinone oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 547.0
HKD3_k127_9241161_2 Large extracellular alpha-helical protein K06894 - - 0.0 2730.0
HKD3_k127_9241161_20 abc transporter atp-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 514.0
HKD3_k127_9241161_21 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 515.0
HKD3_k127_9241161_22 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 511.0
HKD3_k127_9241161_23 Cytochrome C biogenesis protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 481.0
HKD3_k127_9241161_24 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
HKD3_k127_9241161_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 406.0
HKD3_k127_9241161_26 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 385.0
HKD3_k127_9241161_27 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 342.0
HKD3_k127_9241161_28 peptidylprolyl K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
HKD3_k127_9241161_29 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 312.0
HKD3_k127_9241161_3 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 2082.0
HKD3_k127_9241161_30 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 301.0
HKD3_k127_9241161_31 Nucleoprotein polynucleotide-associated enzyme K09912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000122 262.0
HKD3_k127_9241161_32 Chemotaxis protein CheY K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 231.0
HKD3_k127_9241161_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000001149 230.0
HKD3_k127_9241161_34 GntR family transcriptional regulator K07979 - - 0.00000000000000000000000000000000000000000000000000000000000001035 220.0
HKD3_k127_9241161_35 Belongs to the SlyX family K03745 - - 0.00000000000000000000000000000000847 128.0
HKD3_k127_9241161_37 Glycine zipper 2TM domain - - - 0.00000000000000000001939 96.0
HKD3_k127_9241161_4 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1528.0
HKD3_k127_9241161_5 penicillin-binding protein K05367 - 2.4.1.129 0.0 1276.0
HKD3_k127_9241161_6 Trypsin-like serine protease - - - 0.0 1026.0
HKD3_k127_9241161_7 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 8.693e-281 868.0
HKD3_k127_9241161_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 8.671e-268 828.0
HKD3_k127_9241161_9 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.144e-264 817.0
HKD3_k127_9398063_0 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 595.0
HKD3_k127_9398063_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 518.0
HKD3_k127_9398063_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
HKD3_k127_9398063_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002957 240.0
HKD3_k127_9398063_4 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000002624 231.0
HKD3_k127_9398063_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002703 229.0
HKD3_k127_9398063_6 regulation of cell-substrate adhesion K06079 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0010810,GO:0016020,GO:0019867,GO:0030155,GO:0030312,GO:0030313,GO:0031975,GO:0042802,GO:0044462,GO:0044464,GO:0050789,GO:0065007,GO:0071944 - 0.00000000000000000000008732 101.0