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Overview

ID MAG01846
Name HKD3_bin.29
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Reyranellales
Family Reyranellaceae
Genus Reyranella
Species
Assembly information
Completeness (%) 70.1
Contamination (%) 1.0
GC content (%) 67.0
N50 (bp) 9,184
Genome size (bp) 4,326,802

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4376

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1024267_0 amine dehydrogenase activity - - - 0.0 1045.0
HKD3_k127_1024267_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 329.0
HKD3_k127_10305_0 TonB-dependent receptor K16092 - - 1.117e-300 935.0
HKD3_k127_10305_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 612.0
HKD3_k127_10305_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 305.0
HKD3_k127_10305_3 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003847 251.0
HKD3_k127_10305_4 Protein of unknown function (DUF1244) K09948 - - 0.00000000000000000000000000000000000000000000000000001246 189.0
HKD3_k127_10305_5 FCD - - - 0.00000000000000000000000000000000000000000000000001174 198.0
HKD3_k127_10305_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000001079 148.0
HKD3_k127_10305_7 Fe-S protein - - - 0.0000000000000000000000000000000000003359 149.0
HKD3_k127_10305_8 N-formylglutamate amidohydrolase - - - 0.00005332 45.0
HKD3_k127_1043527_0 YidE YbjL duplication K07085 - - 1.414e-244 765.0
HKD3_k127_1049560_0 lactate metabolic process - - - 9.643e-235 733.0
HKD3_k127_1049560_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 565.0
HKD3_k127_1049560_10 - - - - 0.00000000000000000000000001016 109.0
HKD3_k127_1049560_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 564.0
HKD3_k127_1049560_3 Glycine cleavage system T protein K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 298.0
HKD3_k127_1049560_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 292.0
HKD3_k127_1049560_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005974 282.0
HKD3_k127_1049560_6 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004596 261.0
HKD3_k127_1049560_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
HKD3_k127_1049560_8 NIPSNAP - - - 0.000000000000000000000000000000000000000000005018 165.0
HKD3_k127_1049560_9 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000001525 141.0
HKD3_k127_1052007_0 Amidase K02433 - 6.3.5.6,6.3.5.7 7.24e-238 741.0
HKD3_k127_1052007_1 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 383.0
HKD3_k127_1052007_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 317.0
HKD3_k127_1052007_3 SCO1/SenC K07152 - - 0.00000000000000000000000000006643 118.0
HKD3_k127_1055805_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1081.0
HKD3_k127_1055805_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000001256 82.0
HKD3_k127_1095162_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.821e-274 865.0
HKD3_k127_1095162_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 527.0
HKD3_k127_1095162_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 413.0
HKD3_k127_1095162_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 303.0
HKD3_k127_1095162_4 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000001858 222.0
HKD3_k127_1158037_0 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 579.0
HKD3_k127_1158037_1 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 444.0
HKD3_k127_1158037_2 - - - - 0.00000000000000000000000000000000006036 134.0
HKD3_k127_115812_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 601.0
HKD3_k127_115812_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 298.0
HKD3_k127_115812_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 296.0
HKD3_k127_115812_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 279.0
HKD3_k127_115812_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
HKD3_k127_115812_5 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000299 235.0
HKD3_k127_115812_6 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000006142 175.0
HKD3_k127_115812_7 Cupin domain - - - 0.0000000000000000000000000000000006561 141.0
HKD3_k127_1163392_0 DNA helicase K03657 - 3.6.4.12 2.218e-320 983.0
HKD3_k127_1163392_1 ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 422.0
HKD3_k127_1165741_0 Beta-eliminating lyase K01620 - 4.1.2.48 2.497e-198 631.0
HKD3_k127_1165741_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 503.0
HKD3_k127_1165741_2 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 439.0
HKD3_k127_1165741_3 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 440.0
HKD3_k127_1165741_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000006054 230.0
HKD3_k127_1165741_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000001682 199.0
HKD3_k127_1165741_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000001679 100.0
HKD3_k127_1178993_0 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 505.0
HKD3_k127_1178993_1 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 500.0
HKD3_k127_1178993_2 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 479.0
HKD3_k127_1178993_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
HKD3_k127_1184913_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.558e-270 834.0
HKD3_k127_1184913_1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 494.0
HKD3_k127_1190501_0 Enoyl-CoA hydratase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 1.521e-230 721.0
HKD3_k127_1190501_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 7.673e-226 704.0
HKD3_k127_1190501_10 methionine biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 381.0
HKD3_k127_1190501_11 Bacterial regulatory protein, Fis family K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 377.0
HKD3_k127_1190501_12 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008941 287.0
HKD3_k127_1190501_13 transcriptional regulator K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005817 259.0
HKD3_k127_1190501_14 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000004011 160.0
HKD3_k127_1190501_15 ybak prolyl-trna synthetase associated K19055 - - 0.000000000000000000000000000000000001591 143.0
HKD3_k127_1190501_16 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.0000000000000000000000000004051 113.0
HKD3_k127_1190501_17 AraC-like ligand binding domain - - - 0.000000000000000000000002371 106.0
HKD3_k127_1190501_18 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000001025 91.0
HKD3_k127_1190501_2 COG1960 Acyl-CoA dehydrogenases - - - 8.51e-217 677.0
HKD3_k127_1190501_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 1.511e-214 668.0
HKD3_k127_1190501_4 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739 - 2.5.1.48 2.268e-210 659.0
HKD3_k127_1190501_5 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 566.0
HKD3_k127_1190501_6 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 497.0
HKD3_k127_1190501_7 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 488.0
HKD3_k127_1190501_8 chorismate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 464.0
HKD3_k127_1190501_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 456.0
HKD3_k127_1202672_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 554.0
HKD3_k127_1209879_0 Epoxide hydrolase N terminus K21159 - - 1.056e-200 631.0
HKD3_k127_1209879_1 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000001293 118.0
HKD3_k127_1210950_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.296e-270 841.0
HKD3_k127_1210950_1 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 599.0
HKD3_k127_1210950_2 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 561.0
HKD3_k127_1210950_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 538.0
HKD3_k127_1210950_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 509.0
HKD3_k127_1210950_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 457.0
HKD3_k127_1210950_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000203 217.0
HKD3_k127_1210950_7 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000003104 113.0
HKD3_k127_1230186_0 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 405.0
HKD3_k127_1230186_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 394.0
HKD3_k127_1230186_2 Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret K03383 - 3.5.2.15 0.000000000000000000000000000000000000000000000000007614 188.0
HKD3_k127_1230186_3 LysR substrate binding domain - - - 0.0000000000000000000000000006697 115.0
HKD3_k127_1233823_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1499.0
HKD3_k127_1242850_0 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 477.0
HKD3_k127_1242850_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 430.0
HKD3_k127_1242850_2 Putative vitamin uptake transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 302.0
HKD3_k127_1242850_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002405 243.0
HKD3_k127_1242850_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000006653 194.0
HKD3_k127_1243019_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.498e-303 947.0
HKD3_k127_1243019_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.09e-298 924.0
HKD3_k127_1243019_10 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001879 226.0
HKD3_k127_1243019_11 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.0000000000000000000000000000000000000000000000000000005028 193.0
HKD3_k127_1243019_12 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000001224 146.0
HKD3_k127_1243019_13 Amidohydrolase family - - - 0.000000000000000000000000000000006084 127.0
HKD3_k127_1243019_14 Mannose-6-phosphate isomerase - - - 0.000000001591 65.0
HKD3_k127_1243019_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.297e-287 887.0
HKD3_k127_1243019_3 PFAM amidohydrolase K07045 - - 4.097e-247 764.0
HKD3_k127_1243019_4 Belongs to the DEAD box helicase family - - - 1.848e-230 728.0
HKD3_k127_1243019_5 Mate efflux family protein - - - 2.826e-222 698.0
HKD3_k127_1243019_6 Acetyl-CoA hydrolase/transferase C-terminal domain K18288,K22214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 578.0
HKD3_k127_1243019_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 387.0
HKD3_k127_1243019_8 Belongs to the HpcH HpaI aldolase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 323.0
HKD3_k127_1243019_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007365 257.0
HKD3_k127_1287433_0 secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 605.0
HKD3_k127_1287433_1 type II secretion system protein K12511 - - 0.0000000000000000000000000000000000000000000000000000000000006699 226.0
HKD3_k127_1287433_2 pilus assembly protein TadB K12510 - - 0.0000000000000000000000000000000000000000000000004265 200.0
HKD3_k127_1287433_3 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000002353 100.0
HKD3_k127_1290751_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.643e-254 801.0
HKD3_k127_1290751_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 2.819e-214 670.0
HKD3_k127_1290751_10 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005827 278.0
HKD3_k127_1290751_11 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003106 269.0
HKD3_k127_1290751_12 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
HKD3_k127_1290751_13 PFAM FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001522 218.0
HKD3_k127_1290751_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000001949 207.0
HKD3_k127_1290751_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000002802 222.0
HKD3_k127_1290751_16 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000007973 192.0
HKD3_k127_1290751_18 - - - - 0.000000000000000000000000005466 117.0
HKD3_k127_1290751_19 Sodium/hydrogen exchanger family - - - 0.000000000005376 66.0
HKD3_k127_1290751_2 Belongs to the thiolase family K00626 - 2.3.1.9 4.993e-198 623.0
HKD3_k127_1290751_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 591.0
HKD3_k127_1290751_4 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 576.0
HKD3_k127_1290751_5 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 542.0
HKD3_k127_1290751_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 404.0
HKD3_k127_1290751_7 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 357.0
HKD3_k127_1290751_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
HKD3_k127_1290751_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 329.0
HKD3_k127_1297818_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.128e-218 682.0
HKD3_k127_1297818_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 382.0
HKD3_k127_1298441_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.588e-263 819.0
HKD3_k127_1298441_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 305.0
HKD3_k127_1298441_2 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HKD3_k127_1298441_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000001931 183.0
HKD3_k127_1298441_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000002042 158.0
HKD3_k127_1305394_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family - - - 0.0 1123.0
HKD3_k127_1305394_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.566e-220 687.0
HKD3_k127_1307375_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 369.0
HKD3_k127_1307375_1 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 377.0
HKD3_k127_1307375_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 287.0
HKD3_k127_1315864_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1232.0
HKD3_k127_1315864_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 8.019e-314 963.0
HKD3_k127_1315864_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 8.847e-242 758.0
HKD3_k127_1315864_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 325.0
HKD3_k127_1315864_4 PFAM Rieske 2Fe-2S domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
HKD3_k127_1315864_5 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000001824 164.0
HKD3_k127_1315864_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000001238 145.0
HKD3_k127_1315864_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000004247 108.0
HKD3_k127_1315864_8 Putative transposase of IS4/5 family (DUF4096) - - - 0.00000000000000005742 80.0
HKD3_k127_1319024_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 7.527e-242 754.0
HKD3_k127_1319024_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 1.768e-200 627.0
HKD3_k127_1319024_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 624.0
HKD3_k127_1319024_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 565.0
HKD3_k127_1319024_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 567.0
HKD3_k127_1319024_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000002733 237.0
HKD3_k127_1319024_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000001238 181.0
HKD3_k127_1319024_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000006952 149.0
HKD3_k127_1319024_9 receptor - - - 0.00000005012 58.0
HKD3_k127_1332466_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.3e-237 741.0
HKD3_k127_1332466_1 Zn-dependent protease, contains TPR repeats - - - 3.42e-221 693.0
HKD3_k127_1332466_2 Aminotransferase - - - 2.167e-217 677.0
HKD3_k127_1332466_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 567.0
HKD3_k127_1332466_4 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 391.0
HKD3_k127_1332466_5 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 362.0
HKD3_k127_1332466_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003409 263.0
HKD3_k127_1332466_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD3_k127_1336142_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.349e-260 808.0
HKD3_k127_1336142_1 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 573.0
HKD3_k127_1336142_2 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 513.0
HKD3_k127_1336142_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 447.0
HKD3_k127_1336142_4 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 346.0
HKD3_k127_1336142_5 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 341.0
HKD3_k127_1336142_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000003029 211.0
HKD3_k127_1336142_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000003766 170.0
HKD3_k127_1339431_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.77e-286 892.0
HKD3_k127_1339431_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 8.092e-273 845.0
HKD3_k127_1339431_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 456.0
HKD3_k127_1339431_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 354.0
HKD3_k127_1339431_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 299.0
HKD3_k127_1339431_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002918 261.0
HKD3_k127_1339431_6 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000004489 223.0
HKD3_k127_1339431_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000005454 199.0
HKD3_k127_1339431_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000000000003656 184.0
HKD3_k127_1341761_0 COG0569 K transport systems, NAD-binding component K03499 - - 1.9e-263 816.0
HKD3_k127_1341761_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.369e-251 781.0
HKD3_k127_1341761_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 9.697e-224 696.0
HKD3_k127_1341761_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 489.0
HKD3_k127_1341761_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 362.0
HKD3_k127_1343947_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 574.0
HKD3_k127_1343947_1 Cell division and transport-associated protein TolA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 475.0
HKD3_k127_1343947_2 COG0811 Biopolymer transport proteins K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 444.0
HKD3_k127_1343947_3 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 291.0
HKD3_k127_1343947_4 thioesterase K07107 - - 0.00000000000000000000000000000000000000000000007713 169.0
HKD3_k127_1353663_0 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 2.122e-284 878.0
HKD3_k127_1353663_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 519.0
HKD3_k127_1353663_2 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 475.0
HKD3_k127_1353663_3 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000001273 132.0
HKD3_k127_1359765_0 Encapsulating protein for peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 436.0
HKD3_k127_1359765_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 412.0
HKD3_k127_1359765_2 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000003904 221.0
HKD3_k127_1359765_3 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000482 171.0
HKD3_k127_1359765_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000008336 107.0
HKD3_k127_136588_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 9.688e-278 859.0
HKD3_k127_136588_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 604.0
HKD3_k127_136588_2 amidinotransferase K00613 - 2.1.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 540.0
HKD3_k127_136588_3 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 438.0
HKD3_k127_136588_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 436.0
HKD3_k127_1369526_0 acetyl-coa acetyltransferase - - - 5.683e-229 712.0
HKD3_k127_1369526_1 Major Facilitator Superfamily - - - 3.754e-206 646.0
HKD3_k127_1369526_2 COG1176 ABC-type spermidine putrescine transport system permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 514.0
HKD3_k127_1369526_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 463.0
HKD3_k127_1369526_4 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 319.0
HKD3_k127_1369526_5 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 272.0
HKD3_k127_1369526_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000005383 225.0
HKD3_k127_1369526_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02055 - - 0.000000000000000000000000000000000000000000000000000007464 190.0
HKD3_k127_1369526_8 Cytochrome c2 K08738 - - 0.0000000000000000000000001093 115.0
HKD3_k127_1376883_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 573.0
HKD3_k127_1376883_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005323 244.0
HKD3_k127_1376883_2 PFAM NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001231 224.0
HKD3_k127_1379814_0 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 539.0
HKD3_k127_1379814_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 544.0
HKD3_k127_1379814_10 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000004242 134.0
HKD3_k127_1379814_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 506.0
HKD3_k127_1379814_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 432.0
HKD3_k127_1379814_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 390.0
HKD3_k127_1379814_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 356.0
HKD3_k127_1379814_6 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
HKD3_k127_1379814_7 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 308.0
HKD3_k127_1379814_8 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000002592 203.0
HKD3_k127_1379814_9 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.000000000000000000000000000000000000000000000000816 181.0
HKD3_k127_138655_0 HflC and HflK could encode or regulate a protease K04088 - - 9.822e-203 636.0
HKD3_k127_138655_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 589.0
HKD3_k127_138655_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 471.0
HKD3_k127_138655_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007317 336.0
HKD3_k127_138655_4 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 315.0
HKD3_k127_138655_5 Urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000004926 74.0
HKD3_k127_1399083_0 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 528.0
HKD3_k127_1399083_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 449.0
HKD3_k127_1399083_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 349.0
HKD3_k127_1399083_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 339.0
HKD3_k127_1399083_4 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 332.0
HKD3_k127_1405813_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 573.0
HKD3_k127_1405813_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 534.0
HKD3_k127_1405813_12 Zinc-finger domain - - - 0.0000000000000000009924 91.0
HKD3_k127_1405813_2 Lysophospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 534.0
HKD3_k127_1405813_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 436.0
HKD3_k127_1405813_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 402.0
HKD3_k127_1405813_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 364.0
HKD3_k127_1405813_6 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 302.0
HKD3_k127_1405813_8 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002724 241.0
HKD3_k127_1405813_9 oxidation-reduction process K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000000000000000003911 202.0
HKD3_k127_1447674_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.724e-258 801.0
HKD3_k127_1447674_1 trisaccharide binding - - - 1.849e-209 680.0
HKD3_k127_1447674_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
HKD3_k127_1447674_3 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007044 280.0
HKD3_k127_1447674_4 ArsC family - - - 0.0000000000000000000000000000000000000000000000000004095 194.0
HKD3_k127_1447674_5 L-xylulose reductase (NAD+) activity K19336 - - 0.000000000000000000000000000000000000000239 161.0
HKD3_k127_1447674_7 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000002417 135.0
HKD3_k127_1447674_8 glyoxalase K06996 - - 0.0000000000003868 70.0
HKD3_k127_1447674_9 - - - - 0.00000000002738 67.0
HKD3_k127_1453438_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.373e-222 717.0
HKD3_k127_1453438_1 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 479.0
HKD3_k127_1453438_2 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 394.0
HKD3_k127_1453438_3 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 368.0
HKD3_k127_1453438_4 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
HKD3_k127_1453438_5 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
HKD3_k127_1453438_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000001162 68.0
HKD3_k127_1453438_7 TOBE domain K02052 - - 0.0002405 44.0
HKD3_k127_1461371_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.443e-264 821.0
HKD3_k127_1461371_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.561e-238 740.0
HKD3_k127_1461371_2 FAD binding domain K20940 - 1.14.13.218 1.83e-237 737.0
HKD3_k127_1461371_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 614.0
HKD3_k127_1461371_4 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 325.0
HKD3_k127_1461371_5 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001758 251.0
HKD3_k127_1461371_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000004072 234.0
HKD3_k127_1461371_7 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000000000003342 229.0
HKD3_k127_1461371_8 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000000002595 113.0
HKD3_k127_1462979_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 2.593e-236 734.0
HKD3_k127_1462979_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 519.0
HKD3_k127_1462979_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
HKD3_k127_1462979_3 Thiolase, C-terminal domain - - - 0.00000000000000000007041 93.0
HKD3_k127_1475178_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 3.469e-260 807.0
HKD3_k127_1475178_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.025e-202 643.0
HKD3_k127_1475178_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 539.0
HKD3_k127_1475178_3 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 496.0
HKD3_k127_1475178_4 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 421.0
HKD3_k127_1475178_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 385.0
HKD3_k127_1475178_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 331.0
HKD3_k127_1475178_7 regulatory protein K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000006441 259.0
HKD3_k127_1475178_8 - - - - 0.0000000000000000000000000000000000000000000000000000000001024 211.0
HKD3_k127_1475178_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000003316 125.0
HKD3_k127_1479304_0 Acyl-CoA dehydrogenase, C-terminal domain K06446 - - 6.169e-239 750.0
HKD3_k127_1479304_1 Acyl-CoA dehydrogenase, middle domain - - - 2.413e-235 742.0
HKD3_k127_1479304_10 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000001662 207.0
HKD3_k127_1479304_11 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000435 120.0
HKD3_k127_1479304_12 - - - - 0.00000000000000000000008737 107.0
HKD3_k127_1479304_13 Cytochrome c - - - 0.0000000000000000000007188 99.0
HKD3_k127_1479304_14 - - - - 0.00000003099 67.0
HKD3_k127_1479304_15 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000008843 53.0
HKD3_k127_1479304_16 - - - - 0.000009908 55.0
HKD3_k127_1479304_17 - - - - 0.0001227 51.0
HKD3_k127_1479304_2 III protein, CoA-transferase family - - - 3.541e-220 696.0
HKD3_k127_1479304_3 CoA-transferase family III - - - 5.829e-201 649.0
HKD3_k127_1479304_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 414.0
HKD3_k127_1479304_5 AAA ATPase K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 404.0
HKD3_k127_1479304_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 368.0
HKD3_k127_1479304_7 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
HKD3_k127_1479304_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001951 230.0
HKD3_k127_1479304_9 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000026 213.0
HKD3_k127_1483701_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.0 1077.0
HKD3_k127_1483701_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 1.383e-206 650.0
HKD3_k127_1483701_2 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001469 271.0
HKD3_k127_1483701_4 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000184 218.0
HKD3_k127_1483701_5 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000000000000009846 216.0
HKD3_k127_1483701_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000008061 145.0
HKD3_k127_1484321_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.839e-269 856.0
HKD3_k127_1484321_1 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 4.869e-215 674.0
HKD3_k127_1484321_10 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 342.0
HKD3_k127_1484321_11 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 301.0
HKD3_k127_1484321_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD3_k127_1484321_14 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000008408 182.0
HKD3_k127_1484321_16 Protein of unknown function (DUF433) - - - 0.0000000000000000000000006699 106.0
HKD3_k127_1484321_17 - - - - 0.0000000000000000000002658 102.0
HKD3_k127_1484321_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 5.28e-199 625.0
HKD3_k127_1484321_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 513.0
HKD3_k127_1484321_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 507.0
HKD3_k127_1484321_5 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 457.0
HKD3_k127_1484321_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 426.0
HKD3_k127_1484321_7 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 392.0
HKD3_k127_1484321_8 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 366.0
HKD3_k127_1484321_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 359.0
HKD3_k127_14910_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.389e-284 876.0
HKD3_k127_14910_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000001197 169.0
HKD3_k127_14910_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000000008165 156.0
HKD3_k127_1497020_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2905.0
HKD3_k127_1497020_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 4.821e-292 899.0
HKD3_k127_1497020_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
HKD3_k127_1497020_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 406.0
HKD3_k127_1497020_4 Dehydroquinase class II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005906 253.0
HKD3_k127_1497020_5 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000003458 233.0
HKD3_k127_1497020_6 Glutathione-dependent formaldehyde-activating enzyme family protein 3 - - - 0.00000000000000000000000000000000006404 139.0
HKD3_k127_1497020_7 transcriptional regulator - - - 0.000000000000000000001336 100.0
HKD3_k127_1500075_0 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 598.0
HKD3_k127_1500075_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 383.0
HKD3_k127_1500810_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1938.0
HKD3_k127_1500810_1 Transposase DDE domain - - - 0.00000000000000000000001424 100.0
HKD3_k127_1538230_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 432.0
HKD3_k127_1538230_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 427.0
HKD3_k127_1538230_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000003245 143.0
HKD3_k127_1538230_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 399.0
HKD3_k127_1538230_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 362.0
HKD3_k127_1538230_4 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 348.0
HKD3_k127_1538230_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004155 264.0
HKD3_k127_1538230_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006947 270.0
HKD3_k127_1538230_7 - - - - 0.000000000000000000000000000000000000000001772 167.0
HKD3_k127_1538230_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K00561 - 2.1.1.184 0.0000000000000000000000000000000000000007348 156.0
HKD3_k127_1538230_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000007409 143.0
HKD3_k127_1548279_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 6.452e-294 928.0
HKD3_k127_1548279_1 PFAM nitrite and sulphite reductase 4Fe-4S K00366 - 1.7.7.1 9.726e-204 662.0
HKD3_k127_1548279_2 Oxidoreductase NAD-binding domain K00380,K02641,K14338 - 1.14.14.1,1.18.1.2,1.6.2.4,1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 500.0
HKD3_k127_1548279_3 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 460.0
HKD3_k127_1548279_4 ABC transporter K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 407.0
HKD3_k127_1548279_5 Binding-protein-dependent transport system inner membrane component K02050,K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 412.0
HKD3_k127_1548847_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 568.0
HKD3_k127_1548847_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 422.0
HKD3_k127_1548847_2 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000005333 204.0
HKD3_k127_1552098_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.512e-296 925.0
HKD3_k127_1552098_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 620.0
HKD3_k127_1552098_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 565.0
HKD3_k127_1552098_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 547.0
HKD3_k127_1552098_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 483.0
HKD3_k127_1552098_5 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004336 237.0
HKD3_k127_1552098_6 Belongs to the ABC transporter superfamily K02031 - - 0.000213 46.0
HKD3_k127_155242_0 TOBE domain K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 422.0
HKD3_k127_155242_1 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 337.0
HKD3_k127_155242_2 Binding-protein-dependent transport system inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 341.0
HKD3_k127_155242_3 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000002277 135.0
HKD3_k127_1571628_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0 1068.0
HKD3_k127_1571628_1 Amidase K01426 - 3.5.1.4 2.177e-248 779.0
HKD3_k127_1571628_10 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000006626 216.0
HKD3_k127_1571628_11 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000779 206.0
HKD3_k127_1571628_12 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000000002695 134.0
HKD3_k127_1571628_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 5.109e-244 759.0
HKD3_k127_1571628_3 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 506.0
HKD3_k127_1571628_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
HKD3_k127_1571628_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
HKD3_k127_1571628_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000183 268.0
HKD3_k127_1571628_7 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009217 254.0
HKD3_k127_1571628_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002276 237.0
HKD3_k127_1571628_9 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD3_k127_1574638_0 Protein export membrane protein - - - 7.338e-298 942.0
HKD3_k127_1574638_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 3e-296 914.0
HKD3_k127_1574638_10 Membrane-associated sensor, integral membrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
HKD3_k127_1574638_11 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000000000000000000000000000001824 203.0
HKD3_k127_1574638_13 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 - - 0.0000000000000000000000000003249 116.0
HKD3_k127_1574638_14 Protein of unknown function (DUF2892) - - - 0.000000000000000000000005309 102.0
HKD3_k127_1574638_2 PFAM amidohydrolase K07045 - - 2.945e-231 719.0
HKD3_k127_1574638_3 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 7.064e-226 707.0
HKD3_k127_1574638_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 4.889e-206 648.0
HKD3_k127_1574638_5 Aldo keto reductase K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 595.0
HKD3_k127_1574638_6 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
HKD3_k127_1574638_7 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 441.0
HKD3_k127_1574638_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 381.0
HKD3_k127_1574638_9 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
HKD3_k127_1598634_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 467.0
HKD3_k127_1598634_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 361.0
HKD3_k127_1598634_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000002215 182.0
HKD3_k127_1602504_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 352.0
HKD3_k127_1602504_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
HKD3_k127_1602504_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001079 284.0
HKD3_k127_1602504_3 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003388 278.0
HKD3_k127_1602504_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003428 287.0
HKD3_k127_1602504_5 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002121 179.0
HKD3_k127_1614466_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 553.0
HKD3_k127_1614466_1 transport systems, ATPase components K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003242 286.0
HKD3_k127_1614466_2 Catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides K01464 - 3.5.2.2 0.00000000000000002702 84.0
HKD3_k127_1614466_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000001601 67.0
HKD3_k127_1653631_0 Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 376.0
HKD3_k127_1653631_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003629 266.0
HKD3_k127_1653631_2 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000002259 241.0
HKD3_k127_1653631_3 - - - - 0.0000000000000000000000004829 116.0
HKD3_k127_1653631_4 Protein of unknown function (DUF2933) - - - 0.000000000000000007597 86.0
HKD3_k127_1653631_5 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.00000000006944 66.0
HKD3_k127_1659859_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1600.0
HKD3_k127_1659859_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
HKD3_k127_1659859_2 Domain of unknown function (DUF3576) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
HKD3_k127_1659859_3 Gram-negative porin K08720 - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
HKD3_k127_167749_0 Glycosyl transferase, family 2 - - - 1.609e-222 694.0
HKD3_k127_167749_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 456.0
HKD3_k127_167749_2 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 405.0
HKD3_k127_167749_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000003324 235.0
HKD3_k127_1713600_0 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 577.0
HKD3_k127_1713600_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 328.0
HKD3_k127_1717210_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0 1079.0
HKD3_k127_1717210_1 single-stranded-DNA-specific exonuclease recJ K07462 - - 0.0 1045.0
HKD3_k127_1717210_2 Aminotransferase K14261 - - 4.767e-255 801.0
HKD3_k127_1717210_3 homoserine dehydrogenase K00003 - 1.1.1.3 2.787e-232 724.0
HKD3_k127_1717210_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 454.0
HKD3_k127_1717210_5 in Escherichia coli this protein forms a dimer and binds manganese K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 435.0
HKD3_k127_1717210_6 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005587 285.0
HKD3_k127_1717210_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000005572 196.0
HKD3_k127_1717210_8 Belongs to the ompA family - - - 0.00000000000000000000000000001165 123.0
HKD3_k127_1723336_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 8.037e-255 790.0
HKD3_k127_1723336_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 548.0
HKD3_k127_1723336_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 363.0
HKD3_k127_1723336_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000348 219.0
HKD3_k127_1753099_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812,K08351 - 1.7.2.3 0.0 1356.0
HKD3_k127_1753099_1 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 3.17e-252 792.0
HKD3_k127_1753099_2 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 594.0
HKD3_k127_1753099_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 478.0
HKD3_k127_1753099_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000001018 209.0
HKD3_k127_1758757_0 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 541.0
HKD3_k127_1758757_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 398.0
HKD3_k127_1758757_2 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 229.0
HKD3_k127_1781220_0 COG2015, Alkyl sulfatase and related hydrolases - - - 0.0 1069.0
HKD3_k127_1781220_1 Major Facilitator Superfamily - - - 5.685e-213 665.0
HKD3_k127_1781220_2 PFAM Deoxyribonuclease II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 400.0
HKD3_k127_1781220_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 381.0
HKD3_k127_1781220_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 370.0
HKD3_k127_1781220_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 325.0
HKD3_k127_1781220_6 - - - - 0.00000000008636 72.0
HKD3_k127_178512_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 524.0
HKD3_k127_178512_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 381.0
HKD3_k127_178512_2 Redoxin K03386 - 1.11.1.15 0.00003186 46.0
HKD3_k127_1792374_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1146.0
HKD3_k127_1792374_1 COG2030 Acyl dehydratase K14449 - 4.2.1.148 4.535e-202 634.0
HKD3_k127_1792374_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 5.716e-199 623.0
HKD3_k127_1792374_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 515.0
HKD3_k127_1792374_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 466.0
HKD3_k127_1792374_5 Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP K00868 - 2.7.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 331.0
HKD3_k127_1792374_6 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000000000000000000000000000000001149 201.0
HKD3_k127_1792374_7 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000001942 182.0
HKD3_k127_1792374_8 Hydrolyzes N-terminal residues in D-amino acid- containing peptides K01266 - 3.4.11.19 0.00000000000000547 75.0
HKD3_k127_1795220_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.247e-315 969.0
HKD3_k127_1795220_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 5.913e-206 650.0
HKD3_k127_1795220_2 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000001136 85.0
HKD3_k127_1795220_3 nitrite transmembrane transporter activity - - - 0.000007991 58.0
HKD3_k127_179657_0 Flavin-binding monooxygenase-like - - - 2.503e-284 877.0
HKD3_k127_179657_1 Bacterial extracellular solute-binding protein K02012 - - 3.099e-203 635.0
HKD3_k127_179657_10 SnoaL-like polyketide cyclase K15945 - - 0.000000000003848 73.0
HKD3_k127_179657_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 587.0
HKD3_k127_179657_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 462.0
HKD3_k127_179657_4 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 364.0
HKD3_k127_179657_5 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
HKD3_k127_179657_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000002496 203.0
HKD3_k127_179657_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000005534 156.0
HKD3_k127_179657_8 - - - - 0.000000000000000000000002585 104.0
HKD3_k127_179657_9 Aldehyde dehydrogenase family - - - 0.000000000000000000000008096 100.0
HKD3_k127_1797252_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 494.0
HKD3_k127_1797252_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 371.0
HKD3_k127_1797252_3 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
HKD3_k127_1797252_6 HWE histidine kinase - - - 0.00000000000000000000000000000001653 136.0
HKD3_k127_182526_0 Alcohol dehydrogenase GroES-like domain - - - 8.053e-207 644.0
HKD3_k127_182526_1 Nitroreductase K10678 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 431.0
HKD3_k127_182526_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002697 258.0
HKD3_k127_182526_3 Acetyltransferase (GNAT) domain K03829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007553 256.0
HKD3_k127_182526_4 Ion channel - - - 0.0000000000000000000000000000000000002507 146.0
HKD3_k127_182526_5 LTXXQ motif family protein - - - 0.000000000000000006067 91.0
HKD3_k127_183305_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 1.259e-224 706.0
HKD3_k127_183305_1 - - - - 0.000000003183 64.0
HKD3_k127_186500_0 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 554.0
HKD3_k127_186500_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 534.0
HKD3_k127_186500_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
HKD3_k127_186500_3 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 468.0
HKD3_k127_1893847_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 5.678e-244 756.0
HKD3_k127_1893847_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 7.045e-226 707.0
HKD3_k127_1893847_10 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 259.0
HKD3_k127_1893847_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000000000001104 163.0
HKD3_k127_1893847_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 544.0
HKD3_k127_1893847_3 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 541.0
HKD3_k127_1893847_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
HKD3_k127_1893847_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 430.0
HKD3_k127_1893847_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 289.0
HKD3_k127_1893847_8 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
HKD3_k127_1893847_9 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002854 267.0
HKD3_k127_1904820_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 586.0
HKD3_k127_1904820_1 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 421.0
HKD3_k127_1906344_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 317.0
HKD3_k127_1906344_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 284.0
HKD3_k127_1906344_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000347 91.0
HKD3_k127_1906344_3 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000003467 60.0
HKD3_k127_1909799_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0 1039.0
HKD3_k127_1909799_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0 1034.0
HKD3_k127_1909799_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000004487 107.0
HKD3_k127_1909799_11 Protein of unknown function (DUF465) - - - 0.00000000000000000001152 93.0
HKD3_k127_1909799_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000005462 73.0
HKD3_k127_1909799_13 - - - - 0.000007552 58.0
HKD3_k127_1909799_2 histidine ammonia-lyase activity K01745 - 4.3.1.3 2.608e-254 792.0
HKD3_k127_1909799_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 555.0
HKD3_k127_1909799_4 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 306.0
HKD3_k127_1909799_5 Protein of unknown function (DUF2390) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 290.0
HKD3_k127_1909799_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006909 272.0
HKD3_k127_1909799_7 Flavoprotein K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000002218 265.0
HKD3_k127_1909799_9 Protein of unknown function (DUF465) - - - 0.000000000000000000000000005092 111.0
HKD3_k127_1919197_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 391.0
HKD3_k127_1919197_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
HKD3_k127_1919197_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000003346 232.0
HKD3_k127_1919197_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000001133 129.0
HKD3_k127_1919197_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000006088 115.0
HKD3_k127_1929892_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1192.0
HKD3_k127_1929892_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001079 267.0
HKD3_k127_1943325_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.076e-242 758.0
HKD3_k127_1943325_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 316.0
HKD3_k127_1943325_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
HKD3_k127_1943325_3 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001131 250.0
HKD3_k127_1978996_0 Major facilitator superfamily K07552 - - 1.183e-198 625.0
HKD3_k127_1978996_1 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 604.0
HKD3_k127_1978996_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 428.0
HKD3_k127_1978996_3 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001297 245.0
HKD3_k127_198158_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1498.0
HKD3_k127_198158_1 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0 1105.0
HKD3_k127_198158_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 359.0
HKD3_k127_198158_11 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 331.0
HKD3_k127_198158_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003786 285.0
HKD3_k127_198158_13 Ribosomal protein L11 methyltransferase (PrmA) K05929 - 2.1.1.103 0.0000000000000000000000000000000000000000003069 177.0
HKD3_k127_198158_14 Major Facilitator Superfamily - - - 0.0001561 44.0
HKD3_k127_198158_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1048.0
HKD3_k127_198158_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1030.0
HKD3_k127_198158_4 Thymidine phosphorylase K00758 - 2.4.2.4 4.468e-199 633.0
HKD3_k127_198158_5 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 600.0
HKD3_k127_198158_6 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 532.0
HKD3_k127_198158_7 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 437.0
HKD3_k127_198158_8 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 369.0
HKD3_k127_198158_9 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 362.0
HKD3_k127_1982199_0 Sodium/hydrogen exchanger family - - - 2.97e-275 860.0
HKD3_k127_1982199_1 Luciferase-like monooxygenase - - - 1.362e-257 798.0
HKD3_k127_1982199_2 Amidase - - - 2.946e-257 800.0
HKD3_k127_1982199_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 468.0
HKD3_k127_1982199_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 443.0
HKD3_k127_1982199_5 Domain of unknown function (DUF4864) - - - 0.00000000000000000000000000000000000000000000000000000000000000006949 225.0
HKD3_k127_1982199_7 Resolvase - - - 0.000000000001558 68.0
HKD3_k127_2003442_0 ABC transporter K06147,K11004 - - 0.0 1125.0
HKD3_k127_2003442_1 elongator protein 3 miab nifb - - - 0.0 1117.0
HKD3_k127_2003442_10 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 240.0
HKD3_k127_2003442_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002996 233.0
HKD3_k127_2003442_12 Protein of unknown function (DUF3309) - - - 0.0000000000000000000001397 97.0
HKD3_k127_2003442_13 2Fe-2S -binding domain K02192 - - 0.0000000009784 68.0
HKD3_k127_2003442_2 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 1.509e-228 710.0
HKD3_k127_2003442_3 TIGRFAM type I secretion membrane fusion protein, HlyD family K11003 - - 6.611e-209 659.0
HKD3_k127_2003442_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 3.149e-204 649.0
HKD3_k127_2003442_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 569.0
HKD3_k127_2003442_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 569.0
HKD3_k127_2003442_7 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 558.0
HKD3_k127_2003442_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 336.0
HKD3_k127_2003442_9 Belongs to the bacterioferritin family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 289.0
HKD3_k127_2015007_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 557.0
HKD3_k127_2015007_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 378.0
HKD3_k127_2015007_2 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 350.0
HKD3_k127_2015007_3 - - - - 0.00000000000000000000001846 104.0
HKD3_k127_2015007_4 FecR protein - - - 0.00000000000000000000004131 113.0
HKD3_k127_2015007_5 Tetratricopeptide repeat - - - 0.0000000000000004115 85.0
HKD3_k127_2027686_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.253e-267 828.0
HKD3_k127_2027686_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 6.443e-206 646.0
HKD3_k127_2027686_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 462.0
HKD3_k127_2027686_3 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 446.0
HKD3_k127_2027686_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 349.0
HKD3_k127_2027686_5 toxin biosynthetic process K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 302.0
HKD3_k127_2027686_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000531 85.0
HKD3_k127_2037832_0 NMT1-like family K15576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 591.0
HKD3_k127_2037832_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 544.0
HKD3_k127_2037832_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 495.0
HKD3_k127_2037832_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 494.0
HKD3_k127_2037832_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 396.0
HKD3_k127_2037832_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
HKD3_k127_2037832_6 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 306.0
HKD3_k127_2038559_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1503.0
HKD3_k127_2038559_1 Elongation factor SelB, winged helix K03833 - - 0.0 1057.0
HKD3_k127_2038559_2 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 2.186e-235 735.0
HKD3_k127_2038559_3 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 588.0
HKD3_k127_2038559_4 Prokaryotic cytochrome b561 K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 408.0
HKD3_k127_2038559_5 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 350.0
HKD3_k127_2038559_6 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
HKD3_k127_2038559_7 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000001216 171.0
HKD3_k127_2038559_8 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.000000000000000000005729 104.0
HKD3_k127_2038559_9 O-methyltransferase activity - - - 0.000000000001858 78.0
HKD3_k127_2048260_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.702e-277 857.0
HKD3_k127_2048260_1 Glycosyl hydrolases family 15 K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 332.0
HKD3_k127_2048260_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000001326 131.0
HKD3_k127_2080330_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 518.0
HKD3_k127_2080330_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K21323 - 1.14.13.229,1.14.19.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 460.0
HKD3_k127_2092943_0 COG0480 Translation elongation factors (GTPases) K02355 - - 5.161e-310 955.0
HKD3_k127_2092943_1 A circularly permuted ATPgrasp - - - 6.522e-283 887.0
HKD3_k127_2092943_10 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000002208 144.0
HKD3_k127_2092943_11 type II secretion system protein E K02283,K20527 - - 0.00000000000000006824 94.0
HKD3_k127_2092943_12 COG3209 Rhs family protein - - - 0.000000000007478 72.0
HKD3_k127_2092943_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.281e-262 810.0
HKD3_k127_2092943_3 Aminotransferase K00812 - 2.6.1.1 1.062e-225 705.0
HKD3_k127_2092943_4 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 549.0
HKD3_k127_2092943_5 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 497.0
HKD3_k127_2092943_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 447.0
HKD3_k127_2092943_7 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009308 437.0
HKD3_k127_2092943_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 306.0
HKD3_k127_2092943_9 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000000000000000000000002481 237.0
HKD3_k127_2105530_0 Methionine synthase K00548 - 2.1.1.13 0.0 1590.0
HKD3_k127_2105530_1 SNF2 family N-terminal domain - - - 0.0 1227.0
HKD3_k127_2105530_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 601.0
HKD3_k127_2105530_11 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 529.0
HKD3_k127_2105530_12 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 529.0
HKD3_k127_2105530_13 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 487.0
HKD3_k127_2105530_14 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 434.0
HKD3_k127_2105530_15 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 428.0
HKD3_k127_2105530_16 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 400.0
HKD3_k127_2105530_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 409.0
HKD3_k127_2105530_18 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 359.0
HKD3_k127_2105530_19 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 350.0
HKD3_k127_2105530_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.0 1017.0
HKD3_k127_2105530_20 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HKD3_k127_2105530_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 252.0
HKD3_k127_2105530_22 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001903 186.0
HKD3_k127_2105530_23 Fusaric acid resistance protein-like - - - 0.000000000000000000000000000000000000000001246 175.0
HKD3_k127_2105530_25 - - - - 0.0000000000000000000000000000000002475 138.0
HKD3_k127_2105530_26 CoA-transferase family III - - - 0.000000000000000000000000000007172 119.0
HKD3_k127_2105530_3 Acyl-CoA dehydrogenase, middle domain - - - 1.325e-257 796.0
HKD3_k127_2105530_4 Acyl-CoA dehydrogenase, middle domain - - - 1.666e-249 775.0
HKD3_k127_2105530_5 CoA-transferase family III - - - 2.101e-243 761.0
HKD3_k127_2105530_6 Acyl-CoA dehydrogenase, middle domain - - - 5.349e-229 711.0
HKD3_k127_2105530_7 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase - - - 2.475e-212 670.0
HKD3_k127_2105530_8 Homocysteine S-methyltransferase K00548 - 2.1.1.13 1.959e-202 639.0
HKD3_k127_2105530_9 CoA-transferase family III - - - 2.07e-202 645.0
HKD3_k127_2115978_0 COG2873 O-acetylhomoserine sulfhydrylase - - - 5.748e-263 813.0
HKD3_k127_2115978_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 447.0
HKD3_k127_2115978_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 283.0
HKD3_k127_2115978_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000004537 115.0
HKD3_k127_2115978_4 Protein of unknown function (DUF1192) - - - 0.000000000000000000000000002156 111.0
HKD3_k127_2136486_0 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 490.0
HKD3_k127_2136486_1 - - - - 0.00000001969 68.0
HKD3_k127_2136486_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000003356 49.0
HKD3_k127_213712_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 486.0
HKD3_k127_213712_1 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000001161 100.0
HKD3_k127_2137587_0 carnitine dehydratase K07749 - 2.8.3.16 2.132e-219 684.0
HKD3_k127_2137587_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 5.642e-200 625.0
HKD3_k127_2137587_2 carnitine dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 489.0
HKD3_k127_2137587_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 498.0
HKD3_k127_2137587_4 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 379.0
HKD3_k127_2152344_0 Glycosyl transferase, family 2 - - - 4.601e-299 922.0
HKD3_k127_2152344_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 2.92e-237 739.0
HKD3_k127_2152344_2 Putative cyclase - - - 1.455e-222 691.0
HKD3_k127_2152344_3 Major facilitator superfamily - - - 2.805e-194 612.0
HKD3_k127_2152344_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 547.0
HKD3_k127_2152344_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 287.0
HKD3_k127_2152344_7 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001491 286.0
HKD3_k127_2152344_8 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000001096 188.0
HKD3_k127_2152344_9 NUDIX domain - - - 0.000000000000000000000000000000000000007807 153.0
HKD3_k127_2165459_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 1.536e-248 777.0
HKD3_k127_2165459_1 N-terminal half of MaoC dehydratase - - - 3.481e-212 680.0
HKD3_k127_2165459_2 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 320.0
HKD3_k127_2165459_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000004489 52.0
HKD3_k127_2167520_0 Glycosyl transferase family group 2 - - - 0.0 1712.0
HKD3_k127_2167520_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 0.0 1050.0
HKD3_k127_2167520_10 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 429.0
HKD3_k127_2167520_11 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 415.0
HKD3_k127_2167520_12 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 385.0
HKD3_k127_2167520_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 370.0
HKD3_k127_2167520_14 Rieske (2fe-2S) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 372.0
HKD3_k127_2167520_15 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
HKD3_k127_2167520_16 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
HKD3_k127_2167520_17 Protein tyrosine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 322.0
HKD3_k127_2167520_18 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 322.0
HKD3_k127_2167520_19 DTW K05812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 307.0
HKD3_k127_2167520_2 AMP-binding enzyme C-terminal domain K01895,K08295 - 6.2.1.1,6.2.1.32 1.42e-253 814.0
HKD3_k127_2167520_20 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 308.0
HKD3_k127_2167520_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001209 287.0
HKD3_k127_2167520_22 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002766 278.0
HKD3_k127_2167520_23 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007575 270.0
HKD3_k127_2167520_24 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 274.0
HKD3_k127_2167520_26 Belongs to the binding-protein-dependent transport system permease family K01995 - - 0.0000000000000000000000000000000000000000000000001279 184.0
HKD3_k127_2167520_27 - - - - 0.0000000000000000000000000000000000000000000000002318 181.0
HKD3_k127_2167520_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002435 150.0
HKD3_k127_2167520_29 Toprim domain K06919 - - 0.0000000000000000000000000000000000002303 152.0
HKD3_k127_2167520_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 5.892e-211 675.0
HKD3_k127_2167520_30 Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine - - - 0.0000000000000000000000000000000001256 149.0
HKD3_k127_2167520_31 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000005762 134.0
HKD3_k127_2167520_32 glycogen (starch) synthase activity - - - 0.0000000000000000000004931 109.0
HKD3_k127_2167520_33 AAA domain - - - 0.000000000000000001115 91.0
HKD3_k127_2167520_34 Biotin carboxyl carrier protein K02160 - - 0.000000000000007162 78.0
HKD3_k127_2167520_4 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 538.0
HKD3_k127_2167520_5 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 476.0
HKD3_k127_2167520_6 Serine aminopeptidase, S33 K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 469.0
HKD3_k127_2167520_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008462 470.0
HKD3_k127_2167520_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 462.0
HKD3_k127_2167520_9 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 449.0
HKD3_k127_2170804_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.366e-245 761.0
HKD3_k127_2170804_1 Major Facilitator Superfamily - - - 2.719e-215 675.0
HKD3_k127_2170804_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 480.0
HKD3_k127_2170804_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000001273 132.0
HKD3_k127_2176274_0 amine dehydrogenase activity K03418 - 3.5.1.56 0.0 1279.0
HKD3_k127_2176274_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 3.177e-204 639.0
HKD3_k127_2176274_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 7.613e-198 637.0
HKD3_k127_2176274_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
HKD3_k127_2176274_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.000000000000000000000000000000000000000000000000000000000000000000003454 239.0
HKD3_k127_2176274_5 - - - - 0.000000000000000000000682 96.0
HKD3_k127_225850_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 9.028e-295 914.0
HKD3_k127_225850_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 524.0
HKD3_k127_225850_2 Acetyltransferase (GNAT) domain K22479 - - 0.000000000000000000000000000000000000000000000000002732 193.0
HKD3_k127_225850_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000001493 96.0
HKD3_k127_225850_4 Transposase IS200 like - - - 0.00005724 46.0
HKD3_k127_2264682_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1137.0
HKD3_k127_2264682_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 5.409e-310 956.0
HKD3_k127_2264682_2 Histidine kinase - - - 2.733e-212 667.0
HKD3_k127_2264682_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 1.393e-197 623.0
HKD3_k127_2264682_4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 487.0
HKD3_k127_2264682_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 386.0
HKD3_k127_2264682_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000007615 115.0
HKD3_k127_2268785_0 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 1.064e-265 822.0
HKD3_k127_2268785_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 357.0
HKD3_k127_2268785_3 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000002631 108.0
HKD3_k127_2284209_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 1.203e-291 897.0
HKD3_k127_2284209_1 L-carnitine dehydratase bile acid-inducible protein F - - - 2.631e-233 725.0
HKD3_k127_2284209_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
HKD3_k127_2284209_4 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 297.0
HKD3_k127_2284209_5 Cupin domain - - - 0.0000000000000000000000000000000000000157 154.0
HKD3_k127_2289597_0 Amidohydrolase - - - 3.773e-234 727.0
HKD3_k127_2289597_1 Bacterial extracellular solute-binding protein - - - 9.144e-234 729.0
HKD3_k127_2289597_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 525.0
HKD3_k127_2289597_3 HeAt shock protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 485.0
HKD3_k127_2289597_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000004498 219.0
HKD3_k127_2289597_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001641 184.0
HKD3_k127_2289597_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0003476 48.0
HKD3_k127_2290172_0 Transport of potassium into the cell - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 481.0
HKD3_k127_2290172_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 330.0
HKD3_k127_2290172_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003955 241.0
HKD3_k127_2290172_3 CHRD domain - - - 0.00000000000000000000000000000000000000002797 156.0
HKD3_k127_2290172_4 - - - - 0.0000000000000000000000000001748 126.0
HKD3_k127_2290172_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000121 83.0
HKD3_k127_2294810_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 1.062e-234 728.0
HKD3_k127_2294810_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.445e-223 697.0
HKD3_k127_2294810_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 4.192e-195 612.0
HKD3_k127_2294810_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 552.0
HKD3_k127_2294810_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 385.0
HKD3_k127_2294810_5 sequence-specific DNA binding K15539 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 371.0
HKD3_k127_2294810_6 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 315.0
HKD3_k127_2294810_7 Domain of unknown function (DUF4167) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 289.0
HKD3_k127_2294810_8 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001953 242.0
HKD3_k127_2296191_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 7.527e-218 682.0
HKD3_k127_2296191_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 520.0
HKD3_k127_2296191_2 HAD superfamily, subfamily IIIB (Acid phosphatase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 462.0
HKD3_k127_2296191_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 442.0
HKD3_k127_2296191_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system - - - 0.00000003239 54.0
HKD3_k127_2330003_0 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 522.0
HKD3_k127_2330003_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 484.0
HKD3_k127_2330003_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 407.0
HKD3_k127_2330003_3 Amidase - - - 0.0000000000000000000000000000000000002758 146.0
HKD3_k127_2330003_4 - - - - 0.0000000001288 66.0
HKD3_k127_2330003_5 Protein of unknown function (DUF3175) - - - 0.0000000002079 64.0
HKD3_k127_235667_0 AMP-binding enzyme K00666 - - 7.046e-310 958.0
HKD3_k127_235667_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 1.73e-240 747.0
HKD3_k127_235667_10 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000000000000000001283 229.0
HKD3_k127_235667_11 Phosphopantetheine attachment site - - - 0.00000000000000000000000000004869 119.0
HKD3_k127_235667_12 Cation efflux family - - - 0.000000002482 67.0
HKD3_k127_235667_13 Cation efflux family - - - 0.00000001456 65.0
HKD3_k127_235667_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.0001857 44.0
HKD3_k127_235667_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.324e-233 739.0
HKD3_k127_235667_3 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 6.13e-222 691.0
HKD3_k127_235667_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 602.0
HKD3_k127_235667_5 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 522.0
HKD3_k127_235667_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 524.0
HKD3_k127_235667_7 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 446.0
HKD3_k127_235667_8 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 383.0
HKD3_k127_235667_9 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006193 274.0
HKD3_k127_2370381_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 547.0
HKD3_k127_2370381_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 476.0
HKD3_k127_2370381_2 Transition state regulatory protein AbrB K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 445.0
HKD3_k127_2370381_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 397.0
HKD3_k127_2370381_4 PFAM Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000005759 76.0
HKD3_k127_2386011_0 Protein of unknown function (DUF1214) - - - 1.595e-211 667.0
HKD3_k127_2386011_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 541.0
HKD3_k127_2386011_2 Histidine phosphatase superfamily (branch 2) K01093 - 3.1.3.2,3.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
HKD3_k127_2386011_5 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12262 - - 0.00000000000000000000000000000000000000000000000000000002239 203.0
HKD3_k127_2386011_6 DoxX K15977 - - 0.00000000000000000000000000000000000007302 145.0
HKD3_k127_2386011_7 Bacterial extracellular solute-binding protein K02027 - - 0.0005102 43.0
HKD3_k127_2395505_0 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 3.961e-232 722.0
HKD3_k127_2395505_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 482.0
HKD3_k127_2395505_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 443.0
HKD3_k127_2395505_3 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
HKD3_k127_2395505_4 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000001864 94.0
HKD3_k127_2416693_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 554.0
HKD3_k127_2416693_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 460.0
HKD3_k127_2416693_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000001194 233.0
HKD3_k127_2442600_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.492e-207 657.0
HKD3_k127_2442600_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 525.0
HKD3_k127_2442600_2 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 333.0
HKD3_k127_2442600_3 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
HKD3_k127_2442600_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001755 235.0
HKD3_k127_2442600_5 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000000001538 174.0
HKD3_k127_2444392_0 dioxygenase K11159 - - 4.889e-285 878.0
HKD3_k127_2444392_1 Beta-lactamase - - - 2.283e-218 697.0
HKD3_k127_2444392_10 bond formation protein, DsbB - - - 0.00000000000000000000000000000000000000000000000000000000000000004449 226.0
HKD3_k127_2444392_11 FecR protein - - - 0.00000000000000000000000000001255 126.0
HKD3_k127_2444392_12 - - - - 0.00002049 55.0
HKD3_k127_2444392_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 9.201e-212 661.0
HKD3_k127_2444392_3 Methionine synthase K00549 - 2.1.1.14 4.947e-208 650.0
HKD3_k127_2444392_4 Nitronate monooxygenase K00459 - 1.13.12.16 5.584e-201 630.0
HKD3_k127_2444392_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 460.0
HKD3_k127_2444392_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 369.0
HKD3_k127_2444392_7 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 352.0
HKD3_k127_2444392_8 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 333.0
HKD3_k127_2444392_9 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 304.0
HKD3_k127_2447916_0 Dehydratase family K22186 - 4.2.1.82 0.0 1030.0
HKD3_k127_2447916_1 Reductase C-terminal K05297 - 1.18.1.1 9.36e-241 754.0
HKD3_k127_2447916_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 551.0
HKD3_k127_2447916_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 510.0
HKD3_k127_2447916_4 Enoyl-(Acyl carrier protein) reductase K18335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 419.0
HKD3_k127_2447916_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
HKD3_k127_2447916_6 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001113 282.0
HKD3_k127_2447916_7 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000004839 190.0
HKD3_k127_2447916_9 Dehydratase family K22186 - 4.2.1.82 0.0000000000004377 75.0
HKD3_k127_2451064_0 Rod shape-determining protein MreB K03569 - - 2.415e-207 646.0
HKD3_k127_2451064_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 326.0
HKD3_k127_2453314_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.815e-258 799.0
HKD3_k127_2453314_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 9.098e-232 720.0
HKD3_k127_2453314_10 - - - - 0.0000000000000000000000000000000000000000000007654 175.0
HKD3_k127_2453314_11 - - - - 0.0000000000000000000000000000000000000000000059 172.0
HKD3_k127_2453314_12 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000002788 164.0
HKD3_k127_2453314_13 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000449 117.0
HKD3_k127_2453314_14 DDE superfamily endonuclease - - - 0.000134 44.0
HKD3_k127_2453314_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 553.0
HKD3_k127_2453314_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 546.0
HKD3_k127_2453314_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 471.0
HKD3_k127_2453314_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 427.0
HKD3_k127_2453314_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 373.0
HKD3_k127_2453314_7 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003918 260.0
HKD3_k127_2453314_8 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000001009 217.0
HKD3_k127_2453314_9 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000000000000000005351 199.0
HKD3_k127_2471171_0 Transposase C of IS166 homeodomain - - - 7.073e-265 824.0
HKD3_k127_2471171_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 0.0000000000000000000000000000000000000000000000003041 183.0
HKD3_k127_2471171_2 Helix-turn-helix domain - - - 0.000000000000000000000000000009084 122.0
HKD3_k127_2486600_0 Flavin-binding monooxygenase-like K07222 - - 1.046e-303 939.0
HKD3_k127_2486600_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.476e-288 894.0
HKD3_k127_2486600_10 (E1) component, eukaryotic type, alpha subunit K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 330.0
HKD3_k127_2486600_11 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 319.0
HKD3_k127_2486600_12 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 312.0
HKD3_k127_2486600_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
HKD3_k127_2486600_14 Protein of unknown function (DUF1109) - - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
HKD3_k127_2486600_15 FAD binding domain K00480,K14974 - 1.14.13.1,1.14.13.114 0.000000000000000000000000000000000000000000000000000000002708 202.0
HKD3_k127_2486600_16 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000002023 188.0
HKD3_k127_2486600_17 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000003516 183.0
HKD3_k127_2486600_18 dioxygenase K16320,K18243 - 1.14.12.1,1.14.13.172 0.0000000000000000000000000000000000004429 145.0
HKD3_k127_2486600_19 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000001051 128.0
HKD3_k127_2486600_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 519.0
HKD3_k127_2486600_20 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000002652 113.0
HKD3_k127_2486600_21 Receptor family ligand binding region - - - 0.00000000000000000000005336 100.0
HKD3_k127_2486600_22 - - - - 0.000000005924 63.0
HKD3_k127_2486600_23 - - - - 0.0009014 46.0
HKD3_k127_2486600_3 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 476.0
HKD3_k127_2486600_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 437.0
HKD3_k127_2486600_5 Ring hydroxylating alpha subunit (catalytic domain) K16319 - 1.14.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 426.0
HKD3_k127_2486600_6 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 382.0
HKD3_k127_2486600_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 372.0
HKD3_k127_2486600_8 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 364.0
HKD3_k127_2486600_9 helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 343.0
HKD3_k127_2505369_0 Function of homologous gene experimentally demonstrated in an other organism K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 515.0
HKD3_k127_2505369_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 427.0
HKD3_k127_2505369_2 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 318.0
HKD3_k127_2505369_3 - - - - 0.000000000000000000000000000000000000000007052 160.0
HKD3_k127_2530113_0 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 484.0
HKD3_k127_2530113_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 434.0
HKD3_k127_2530113_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002199 269.0
HKD3_k127_2530113_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000003335 148.0
HKD3_k127_2530113_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000004093 72.0
HKD3_k127_2537233_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 469.0
HKD3_k127_2537233_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 366.0
HKD3_k127_2537233_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00002687 57.0
HKD3_k127_2576864_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 1.834e-296 915.0
HKD3_k127_2576864_1 Paraquat-inducible protein B K06192 - - 1.209e-253 793.0
HKD3_k127_2576864_10 Protein conserved in bacteria K09857 - - 0.000000000000000000000000000000000000000000000000000000000000000005881 245.0
HKD3_k127_2576864_11 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000002904 215.0
HKD3_k127_2576864_12 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000006855 200.0
HKD3_k127_2576864_2 Ammonium transporter K03320 - - 5.669e-250 778.0
HKD3_k127_2576864_3 COG0004 Ammonia permease K03320 - - 2.166e-245 766.0
HKD3_k127_2576864_4 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 2.79e-223 699.0
HKD3_k127_2576864_5 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 9e-213 666.0
HKD3_k127_2576864_6 paraquat-inducible protein A K03808 - - 2.012e-202 640.0
HKD3_k127_2576864_7 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 526.0
HKD3_k127_2576864_8 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 434.0
HKD3_k127_2576864_9 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 387.0
HKD3_k127_2577173_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 8.346e-234 730.0
HKD3_k127_2577173_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000003156 186.0
HKD3_k127_2593947_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.18e-262 821.0
HKD3_k127_2593947_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 500.0
HKD3_k127_2593947_2 AMP-binding enzyme K12508 - 6.2.1.34 0.0000000000003765 83.0
HKD3_k127_2593947_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000002786 55.0
HKD3_k127_2599246_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0 1014.0
HKD3_k127_2599246_1 protein conserved in bacteria K09989 - - 9.36e-255 788.0
HKD3_k127_2599246_10 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000003439 195.0
HKD3_k127_2599246_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 538.0
HKD3_k127_2599246_3 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 454.0
HKD3_k127_2599246_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 395.0
HKD3_k127_2599246_5 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 385.0
HKD3_k127_2599246_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 376.0
HKD3_k127_2599246_7 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000009864 216.0
HKD3_k127_2599246_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000199 214.0
HKD3_k127_2599246_9 Cytochrome C' - - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
HKD3_k127_2602709_0 Radical SAM superfamily K11779 - 2.5.1.77 0.0 1321.0
HKD3_k127_2602709_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 567.0
HKD3_k127_2602709_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 484.0
HKD3_k127_2602709_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 459.0
HKD3_k127_2602709_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 364.0
HKD3_k127_2602709_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 336.0
HKD3_k127_2602709_6 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 316.0
HKD3_k127_2602709_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000133 276.0
HKD3_k127_2602709_8 Shikimate kinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000003145 243.0
HKD3_k127_2602709_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000005018 175.0
HKD3_k127_2606037_0 CoA-transferase family III - - - 1.142e-235 732.0
HKD3_k127_2606037_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 542.0
HKD3_k127_2606037_2 belongs to the nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 429.0
HKD3_k127_2606037_3 FAD binding domain K22270 - 1.14.13.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 360.0
HKD3_k127_2606037_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 319.0
HKD3_k127_2606037_5 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 295.0
HKD3_k127_2606037_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000001014 203.0
HKD3_k127_2606037_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000003216 139.0
HKD3_k127_2606037_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000005189 91.0
HKD3_k127_2609220_0 AIR synthase related protein, C-terminal domain - - - 1.483e-294 913.0
HKD3_k127_2609220_1 oligosaccharyl transferase activity - - - 4.799e-197 626.0
HKD3_k127_2610164_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 468.0
HKD3_k127_2610164_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 421.0
HKD3_k127_2610164_2 TIGRFAM 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 417.0
HKD3_k127_2610164_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
HKD3_k127_2612737_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 4.71e-247 764.0
HKD3_k127_2612737_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 9.04e-243 758.0
HKD3_k127_2612737_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000001039 198.0
HKD3_k127_2612737_11 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000001845 196.0
HKD3_k127_2612737_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001076 183.0
HKD3_k127_2612737_13 rubredoxin - - - 0.00000000000000000000000008409 112.0
HKD3_k127_2612737_14 - - - - 0.00000001472 59.0
HKD3_k127_2612737_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 600.0
HKD3_k127_2612737_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 533.0
HKD3_k127_2612737_4 drug resistance transporter, Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 507.0
HKD3_k127_2612737_5 Methyl-transferase K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 494.0
HKD3_k127_2612737_6 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 432.0
HKD3_k127_2612737_7 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
HKD3_k127_2612737_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
HKD3_k127_2612737_9 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
HKD3_k127_2636227_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.04e-321 990.0
HKD3_k127_2636227_1 Binds the 23S rRNA K02909 - - 0.000000002081 59.0
HKD3_k127_2646743_0 Belongs to the ABC transporter superfamily K13896 - - 6.139e-296 925.0
HKD3_k127_2646743_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 1.052e-221 696.0
HKD3_k127_2646743_10 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000009035 237.0
HKD3_k127_2646743_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000001259 227.0
HKD3_k127_2646743_12 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000001803 162.0
HKD3_k127_2646743_13 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000006915 55.0
HKD3_k127_2646743_2 transport system, permease component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 582.0
HKD3_k127_2646743_3 transport system, permease component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 576.0
HKD3_k127_2646743_4 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 576.0
HKD3_k127_2646743_5 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 402.0
HKD3_k127_2646743_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 330.0
HKD3_k127_2646743_7 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 318.0
HKD3_k127_2646743_8 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 315.0
HKD3_k127_2646743_9 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001377 257.0
HKD3_k127_2649051_0 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 443.0
HKD3_k127_2649051_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 394.0
HKD3_k127_2649051_2 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 323.0
HKD3_k127_2649051_3 ABC-type tungstate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000004693 227.0
HKD3_k127_2649051_4 - - - - 0.00000000000000000000000000000000000000000007109 165.0
HKD3_k127_2652569_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 506.0
HKD3_k127_2652569_1 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 455.0
HKD3_k127_2652569_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 294.0
HKD3_k127_2698208_0 AcrB/AcrD/AcrF family - - - 0.0 1738.0
HKD3_k127_2698208_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 4.577e-214 668.0
HKD3_k127_2698208_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 6.192e-198 620.0
HKD3_k127_2698208_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 556.0
HKD3_k127_2698208_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 499.0
HKD3_k127_2698208_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 455.0
HKD3_k127_2698208_6 Protein of unknown function (DUF3225) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004505 237.0
HKD3_k127_2698208_7 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
HKD3_k127_2698208_8 ABC transporter K02035 - - 0.000000000000000000000000000000000000000000000000000000000007941 223.0
HKD3_k127_2698208_9 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000004614 154.0
HKD3_k127_2704253_0 Sugar (and other) transporter K05548,K08369 - - 6.323e-235 737.0
HKD3_k127_2704253_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
HKD3_k127_2704253_2 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 338.0
HKD3_k127_2719269_0 HELICc2 K03722 - 3.6.4.12 0.0 1630.0
HKD3_k127_2719269_1 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 434.0
HKD3_k127_2719269_2 B-1 B cell differentiation K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 277.0
HKD3_k127_2719269_3 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000001016 216.0
HKD3_k127_2719269_4 Papain family cysteine protease - - - 0.0000000003455 64.0
HKD3_k127_2725231_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1188.0
HKD3_k127_2725231_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 2.796e-201 629.0
HKD3_k127_2725231_10 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000003328 174.0
HKD3_k127_2725231_12 thioesterase K07107 - - 0.000000000000000000000004257 101.0
HKD3_k127_2725231_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 2.536e-199 624.0
HKD3_k127_2725231_3 Protein conserved in bacteria K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 510.0
HKD3_k127_2725231_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 451.0
HKD3_k127_2725231_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 299.0
HKD3_k127_2725231_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 306.0
HKD3_k127_2725231_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000009679 272.0
HKD3_k127_2725231_8 Ureidoglycolate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003775 239.0
HKD3_k127_2725231_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005061 229.0
HKD3_k127_2736064_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1930.0
HKD3_k127_2736064_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 326.0
HKD3_k127_2736064_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 295.0
HKD3_k127_2736064_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
HKD3_k127_2736064_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000009574 124.0
HKD3_k127_2750261_0 Heat shock 70 kDa protein K04043 - - 0.0 1107.0
HKD3_k127_2750261_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 1.443e-217 678.0
HKD3_k127_2750261_10 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008332 276.0
HKD3_k127_2750261_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000008441 240.0
HKD3_k127_2750261_12 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000003352 150.0
HKD3_k127_2750261_2 PFAM extracellular solute-binding protein family 5 K02035 - - 4.802e-207 656.0
HKD3_k127_2750261_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 7.572e-204 640.0
HKD3_k127_2750261_4 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 471.0
HKD3_k127_2750261_5 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 464.0
HKD3_k127_2750261_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 453.0
HKD3_k127_2750261_7 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 420.0
HKD3_k127_2750261_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 406.0
HKD3_k127_2750261_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 291.0
HKD3_k127_2805110_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.715e-263 816.0
HKD3_k127_280583_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 604.0
HKD3_k127_280583_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 587.0
HKD3_k127_280583_10 Caspase domain - - - 0.00000000000005258 80.0
HKD3_k127_280583_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000007269 70.0
HKD3_k127_280583_2 peptidyl-tyrosine modification K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 492.0
HKD3_k127_280583_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 392.0
HKD3_k127_280583_4 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 392.0
HKD3_k127_280583_5 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HKD3_k127_280583_6 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000003135 208.0
HKD3_k127_280583_7 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000001406 184.0
HKD3_k127_280583_8 Cytochrome c K17230 - - 0.00000000000000000000000000000000000000000000004088 177.0
HKD3_k127_280583_9 Pyrroloquinoline quinone biosynthesis protein D K06138 - - 0.000000000000000000000000009582 111.0
HKD3_k127_2835969_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 3.788e-279 863.0
HKD3_k127_2836220_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.782e-267 823.0
HKD3_k127_2836220_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 534.0
HKD3_k127_2836220_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 422.0
HKD3_k127_2849423_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1041.0
HKD3_k127_2849423_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.115e-268 834.0
HKD3_k127_2849423_10 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
HKD3_k127_2849423_11 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002848 283.0
HKD3_k127_2849423_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005452 274.0
HKD3_k127_2849423_13 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD3_k127_2849423_14 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000004535 195.0
HKD3_k127_2849423_2 Aminotransferase class-III - - - 3.516e-264 816.0
HKD3_k127_2849423_3 FAD dependent oxidoreductase - - - 7.493e-214 668.0
HKD3_k127_2849423_4 Rieske [2Fe-2S] domain - - - 1.513e-208 683.0
HKD3_k127_2849423_5 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 565.0
HKD3_k127_2849423_6 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 558.0
HKD3_k127_2849423_7 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 395.0
HKD3_k127_2849423_8 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
HKD3_k127_2849423_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 350.0
HKD3_k127_2849730_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1159.0
HKD3_k127_2849730_1 III protein, CoA-transferase family - - - 4.931e-241 746.0
HKD3_k127_2849730_10 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000133 121.0
HKD3_k127_2849730_11 - - - - 0.0000000000000000000000005996 121.0
HKD3_k127_2849730_2 Periplasmic binding protein - - - 5.433e-222 726.0
HKD3_k127_2849730_3 Belongs to the binding-protein-dependent transport system permease family - - - 2.811e-202 632.0
HKD3_k127_2849730_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 594.0
HKD3_k127_2849730_5 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 515.0
HKD3_k127_2849730_6 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 499.0
HKD3_k127_2849730_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 490.0
HKD3_k127_2849730_8 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 466.0
HKD3_k127_2849730_9 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 301.0
HKD3_k127_2853641_0 GTP-binding protein TypA K06207 - - 0.0 1057.0
HKD3_k127_2853641_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0 1036.0
HKD3_k127_2853641_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 418.0
HKD3_k127_2853641_3 Stringent starvation protein B K09985 - - 0.000000003675 60.0
HKD3_k127_2855128_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.507e-280 873.0
HKD3_k127_2855128_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 6.164e-227 711.0
HKD3_k127_2855128_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HKD3_k127_2855128_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 1.311e-196 616.0
HKD3_k127_2855128_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 517.0
HKD3_k127_2855128_4 Peptidase family S49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 399.0
HKD3_k127_2855128_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 361.0
HKD3_k127_2855128_6 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 347.0
HKD3_k127_2855128_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 346.0
HKD3_k127_2855128_8 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 299.0
HKD3_k127_2855128_9 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003721 279.0
HKD3_k127_2858063_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1317.0
HKD3_k127_2858063_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 6.671e-222 701.0
HKD3_k127_2858063_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17202,K17205,K17213 - - 0.00000000000000000000000000000000000000000000000000000001165 209.0
HKD3_k127_2858063_3 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000366 174.0
HKD3_k127_2858063_4 photosystem II stabilization K02237 - - 0.00000000000000000000000000000406 124.0
HKD3_k127_2876065_0 TAP-like protein - - - 7.863e-272 848.0
HKD3_k127_2876065_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.096e-258 799.0
HKD3_k127_2876065_10 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 407.0
HKD3_k127_2876065_11 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 373.0
HKD3_k127_2876065_12 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 293.0
HKD3_k127_2876065_14 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007268 274.0
HKD3_k127_2876065_15 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004121 247.0
HKD3_k127_2876065_16 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009379 246.0
HKD3_k127_2876065_17 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000002534 241.0
HKD3_k127_2876065_2 Proton-conducting membrane transporter - - - 1.116e-253 799.0
HKD3_k127_2876065_3 Major Facilitator Superfamily - - - 1.384e-240 747.0
HKD3_k127_2876065_4 COG0665 Glycine D-amino acid oxidases (deaminating) K00285,K21060 - 1.4.5.1 1.547e-228 711.0
HKD3_k127_2876065_5 Proton-conducting membrane transporter K12141 - - 1.705e-206 655.0
HKD3_k127_2876065_6 NADH-ubiquinone oxidoreductase chain 49kDa - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 612.0
HKD3_k127_2876065_7 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 526.0
HKD3_k127_2876065_8 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 508.0
HKD3_k127_2876065_9 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 419.0
HKD3_k127_2876658_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 7.025e-224 696.0
HKD3_k127_2876658_1 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 479.0
HKD3_k127_2876658_2 Helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 400.0
HKD3_k127_2876658_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 384.0
HKD3_k127_2876658_4 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 329.0
HKD3_k127_2876658_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 305.0
HKD3_k127_2876658_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 287.0
HKD3_k127_2876658_7 Belongs to the UPF0310 family - - - 0.000000000000000000000000000000000000000000000000002766 186.0
HKD3_k127_2889164_0 COG1960 Acyl-CoA dehydrogenases - - - 3.419e-263 812.0
HKD3_k127_2889164_1 Bacterial protein of unknown function (DUF853) K06915 - - 1.697e-254 801.0
HKD3_k127_2889164_10 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 396.0
HKD3_k127_2889164_11 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
HKD3_k127_2889164_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
HKD3_k127_2889164_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
HKD3_k127_2889164_14 myo-inosose-2 dehydratase activity K01805,K19974 - 5.1.3.35,5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 346.0
HKD3_k127_2889164_15 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 308.0
HKD3_k127_2889164_16 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
HKD3_k127_2889164_17 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001607 263.0
HKD3_k127_2889164_18 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
HKD3_k127_2889164_19 deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000003176 211.0
HKD3_k127_2889164_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.971e-201 635.0
HKD3_k127_2889164_20 Heavy-metal resistance - - - 0.000000000000000000000000000000000000000000000000002503 194.0
HKD3_k127_2889164_21 - - - - 0.0000000000000000000000000000000000000000000001081 173.0
HKD3_k127_2889164_22 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000002479 150.0
HKD3_k127_2889164_23 - - - - 0.00000000000000000005439 93.0
HKD3_k127_2889164_24 Ferredoxin - - - 0.0000009226 53.0
HKD3_k127_2889164_3 His Kinase A (phosphoacceptor) domain - - - 5.24e-200 633.0
HKD3_k127_2889164_4 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 518.0
HKD3_k127_2889164_5 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 494.0
HKD3_k127_2889164_6 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 424.0
HKD3_k127_2889164_7 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 404.0
HKD3_k127_2889164_8 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 406.0
HKD3_k127_2889164_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 389.0
HKD3_k127_2893507_0 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0 1402.0
HKD3_k127_2893507_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0 1016.0
HKD3_k127_2893507_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004819 270.0
HKD3_k127_2893507_12 - - - - 0.00000000000000000000000000001415 123.0
HKD3_k127_2893507_3 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 4.679e-207 662.0
HKD3_k127_2893507_4 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 567.0
HKD3_k127_2893507_5 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 534.0
HKD3_k127_2893507_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 497.0
HKD3_k127_2893507_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 440.0
HKD3_k127_2893507_8 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 436.0
HKD3_k127_2893507_9 Glutathione S-transferase, C-terminal domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 357.0
HKD3_k127_2906911_0 DNA polymerase K02337 - 2.7.7.7 0.0 1709.0
HKD3_k127_2906911_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 571.0
HKD3_k127_2906911_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 512.0
HKD3_k127_2906911_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 478.0
HKD3_k127_2906911_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 441.0
HKD3_k127_2906911_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 320.0
HKD3_k127_2906911_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000005943 71.0
HKD3_k127_2926508_0 Mechanosensitive ion channel - - - 1.635e-253 801.0
HKD3_k127_2926508_1 Metallo-beta-lactamase superfamily - - - 1.819e-216 673.0
HKD3_k127_2926508_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 579.0
HKD3_k127_2926508_3 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 548.0
HKD3_k127_2926508_4 Aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 511.0
HKD3_k127_2926508_5 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 481.0
HKD3_k127_2941757_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 505.0
HKD3_k127_2941757_1 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000009511 115.0
HKD3_k127_2941757_2 CoA-transferase family III - - - 0.000000000002485 68.0
HKD3_k127_2958769_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 1.07e-252 797.0
HKD3_k127_2958769_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 1.741e-232 722.0
HKD3_k127_2958769_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 407.0
HKD3_k127_2958769_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001651 279.0
HKD3_k127_2958769_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 261.0
HKD3_k127_2958769_5 Glycosyl Transferase - - - 0.000000000000000000000000000000005761 130.0
HKD3_k127_296012_0 Protein of unknown function (DUF445) - - - 2.742e-231 720.0
HKD3_k127_296012_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 451.0
HKD3_k127_296012_2 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007168 221.0
HKD3_k127_296012_3 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000002477 203.0
HKD3_k127_296012_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000549 98.0
HKD3_k127_2964357_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 558.0
HKD3_k127_2964357_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000002463 209.0
HKD3_k127_2985257_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 4.491e-291 900.0
HKD3_k127_2985257_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.323e-222 702.0
HKD3_k127_2985257_2 FAD binding domain - - - 3.161e-209 659.0
HKD3_k127_2985257_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
HKD3_k127_2985257_4 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000007351 173.0
HKD3_k127_2985257_5 Response regulator receiver - - - 0.00000000000000000008609 94.0
HKD3_k127_2985257_6 Belongs to the UPF0312 family - - - 0.00002358 49.0
HKD3_k127_2994108_0 Histidine kinase - - - 0.0 1062.0
HKD3_k127_2994108_1 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 282.0
HKD3_k127_2994108_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003638 285.0
HKD3_k127_2994108_4 carboxymuconolactone decarboxylase - - - 0.0000000002913 61.0
HKD3_k127_3023071_0 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 591.0
HKD3_k127_3023071_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 334.0
HKD3_k127_3023071_2 Probable cobalt transporter subunit (CbtA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001913 243.0
HKD3_k127_3023071_3 Protein of unknown function (DUF1636) - - - 0.0000000000000000000000000000000000000000008086 168.0
HKD3_k127_3023071_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000007979 160.0
HKD3_k127_3023071_5 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 0.00000000000000000000000000000000000006928 143.0
HKD3_k127_3023071_6 Probable cobalt transporter subunit (CbtB) - - - 0.000000000001303 79.0
HKD3_k127_3043633_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1079.0
HKD3_k127_3043633_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 1.212e-296 926.0
HKD3_k127_3043633_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 9.087e-203 633.0
HKD3_k127_3043633_3 Dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 435.0
HKD3_k127_3043633_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 421.0
HKD3_k127_3043633_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000007288 193.0
HKD3_k127_3050805_0 COG0477 Permeases of the major facilitator superfamily - - - 9.238e-211 660.0
HKD3_k127_3050805_1 Acetamidase/Formamidase family - - - 1.018e-196 618.0
HKD3_k127_3050805_10 Alpha/beta hydrolase family - - - 0.000000000009138 73.0
HKD3_k127_3050805_2 Permease MlaE K02066 - - 2.833e-195 623.0
HKD3_k127_3050805_3 MlaD protein K02067,K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 537.0
HKD3_k127_3050805_4 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 536.0
HKD3_k127_3050805_5 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 439.0
HKD3_k127_3050805_6 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 451.0
HKD3_k127_3050805_7 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 420.0
HKD3_k127_3050805_8 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000002737 250.0
HKD3_k127_3050805_9 NfeD-like C-terminal, partner-binding K07340 - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
HKD3_k127_3055828_0 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 551.0
HKD3_k127_3055828_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 538.0
HKD3_k127_3055828_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 496.0
HKD3_k127_3055828_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 428.0
HKD3_k127_3055828_4 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005962 271.0
HKD3_k127_3055828_5 Transcription elongation factor, GreA/GreB, C-term K06140 - - 0.000000000000000000000000000000000000000000000000000007168 195.0
HKD3_k127_3055828_6 ABC transporter permease - - - 0.00000001204 63.0
HKD3_k127_3055828_7 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.00000004144 59.0
HKD3_k127_306299_0 Cytochrome c K02198 - - 0.0 1212.0
HKD3_k127_306299_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 392.0
HKD3_k127_306299_2 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 295.0
HKD3_k127_306299_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 237.0
HKD3_k127_306299_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000000000000003064 103.0
HKD3_k127_3072358_0 LUD domain K18929 - - 9.796e-279 870.0
HKD3_k127_3072358_1 Gram-negative porin K08720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 482.0
HKD3_k127_3072358_2 (Fe-S) oxidoreductase K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 448.0
HKD3_k127_3072358_3 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 375.0
HKD3_k127_3072358_4 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 353.0
HKD3_k127_3086524_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.38e-253 787.0
HKD3_k127_3086524_1 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 587.0
HKD3_k127_3086524_10 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 325.0
HKD3_k127_3086524_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 314.0
HKD3_k127_3086524_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001401 252.0
HKD3_k127_3086524_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000006594 230.0
HKD3_k127_3086524_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000009909 220.0
HKD3_k127_3086524_15 AIG2-like family - - - 0.000000000000000000000000000000000000000000000000000000000025 211.0
HKD3_k127_3086524_16 Domain of unknown function (DUF1476) - - - 0.00000000000000000000000000000000000000001125 155.0
HKD3_k127_3086524_17 PRC-barrel domain - - - 0.00000000000000000000000000000002235 126.0
HKD3_k127_3086524_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 567.0
HKD3_k127_3086524_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 550.0
HKD3_k127_3086524_4 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 511.0
HKD3_k127_3086524_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 453.0
HKD3_k127_3086524_6 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 428.0
HKD3_k127_3086524_7 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 429.0
HKD3_k127_3086524_8 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 391.0
HKD3_k127_3086524_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 386.0
HKD3_k127_3095365_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 601.0
HKD3_k127_3095365_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 401.0
HKD3_k127_3095365_2 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 293.0
HKD3_k127_3128685_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 3.033e-215 671.0
HKD3_k127_3128685_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 343.0
HKD3_k127_3128685_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 313.0
HKD3_k127_3128685_3 Protein conserved in bacteria K09962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000453 282.0
HKD3_k127_3128685_5 decarboxylase K01607 - 4.1.1.44 0.0000000000000000004409 94.0
HKD3_k127_3150641_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.938e-231 745.0
HKD3_k127_3150641_1 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 2.179e-202 638.0
HKD3_k127_3150641_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 332.0
HKD3_k127_3150641_11 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 316.0
HKD3_k127_3150641_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 289.0
HKD3_k127_3150641_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 293.0
HKD3_k127_3150641_14 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000002555 223.0
HKD3_k127_3150641_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000195 185.0
HKD3_k127_3150641_16 Methylmuconolactone methyl-isomerase - - - 0.000000000000000000000000000000000000000000000003933 179.0
HKD3_k127_3150641_18 - - - - 0.00000000000000000000000000000000008495 141.0
HKD3_k127_3150641_19 nucleotidyltransferase activity K00984 - 2.7.7.47 0.000001741 53.0
HKD3_k127_3150641_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 544.0
HKD3_k127_3150641_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 480.0
HKD3_k127_3150641_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 473.0
HKD3_k127_3150641_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 471.0
HKD3_k127_3150641_6 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 437.0
HKD3_k127_3150641_7 COG0477 Permeases of the major facilitator superfamily K13021 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 421.0
HKD3_k127_3150641_8 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HKD3_k127_3150641_9 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 386.0
HKD3_k127_3160660_0 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 4.833e-286 899.0
HKD3_k127_3160660_1 Protein of unknown function (DUF917) K09703 - - 7.571e-211 658.0
HKD3_k127_3160660_10 Ketosteroid isomerase-related protein - - - 0.0000000000000000000003295 102.0
HKD3_k127_3160660_2 Protein of unknown function (DUF917) K09703 - - 2.57e-205 642.0
HKD3_k127_3160660_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 559.0
HKD3_k127_3160660_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 512.0
HKD3_k127_3160660_5 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 520.0
HKD3_k127_3160660_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 379.0
HKD3_k127_3160660_7 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 338.0
HKD3_k127_3160660_8 AroM protein K14591 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 332.0
HKD3_k127_3180544_0 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 484.0
HKD3_k127_3180544_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 398.0
HKD3_k127_3180544_2 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 330.0
HKD3_k127_3180544_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 307.0
HKD3_k127_3180544_4 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000000000000002586 188.0
HKD3_k127_3180544_5 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000001941 117.0
HKD3_k127_3180544_6 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000004852 97.0
HKD3_k127_3180544_7 carboxylate-amine ligase domain protein - - - 0.000000000008643 72.0
HKD3_k127_3206266_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
HKD3_k127_3206266_1 Belongs to the HpcH HpaI aldolase family K01644 GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0071704 4.1.3.34 0.0000000000002763 70.0
HKD3_k127_3213715_0 Amidase - - - 1.232e-279 864.0
HKD3_k127_3213715_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 522.0
HKD3_k127_3214077_0 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0 1007.0
HKD3_k127_3214077_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.94e-286 900.0
HKD3_k127_3214077_10 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 562.0
HKD3_k127_3214077_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 543.0
HKD3_k127_3214077_12 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 509.0
HKD3_k127_3214077_13 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 478.0
HKD3_k127_3214077_14 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 379.0
HKD3_k127_3214077_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 292.0
HKD3_k127_3214077_16 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002032 190.0
HKD3_k127_3214077_18 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000003106 103.0
HKD3_k127_3214077_19 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000007173 75.0
HKD3_k127_3214077_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.021e-256 795.0
HKD3_k127_3214077_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.279e-244 761.0
HKD3_k127_3214077_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.778e-241 754.0
HKD3_k127_3214077_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 3.247e-239 747.0
HKD3_k127_3214077_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.747e-219 694.0
HKD3_k127_3214077_7 Belongs to the SEDS family K03588 - - 5.532e-215 671.0
HKD3_k127_3214077_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.308e-205 643.0
HKD3_k127_3214077_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 586.0
HKD3_k127_3227859_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 485.0
HKD3_k127_3227859_1 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 293.0
HKD3_k127_3229795_0 Phosphotransferase enzyme family - - - 3.879e-195 638.0
HKD3_k127_3229795_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 479.0
HKD3_k127_3229795_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 426.0
HKD3_k127_3229795_3 TIGRFAM L-lactate transport K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 359.0
HKD3_k127_32367_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 7.173e-238 737.0
HKD3_k127_32367_1 Major Facilitator Superfamily - - - 3.711e-229 716.0
HKD3_k127_32367_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000376 210.0
HKD3_k127_32367_11 bacterial (prokaryotic) histone like domain - - - 0.00000000000000000000000000000000000000000000002277 172.0
HKD3_k127_32367_12 Protein conserved in bacteria K09984 - - 0.00000000000000000000000000000000000000000000006505 172.0
HKD3_k127_32367_13 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000006462 139.0
HKD3_k127_32367_14 Putative peptidoglycan binding domain - - - 0.00006321 55.0
HKD3_k127_32367_2 ABC transporter substrate-binding protein K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 569.0
HKD3_k127_32367_3 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 536.0
HKD3_k127_32367_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 521.0
HKD3_k127_32367_5 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
HKD3_k127_32367_6 DJ-1/PfpI family K18199 - 4.2.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 374.0
HKD3_k127_32367_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 377.0
HKD3_k127_32367_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 325.0
HKD3_k127_32367_9 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HKD3_k127_3256365_0 Sodium/hydrogen exchanger family K03316 - - 0.0 1251.0
HKD3_k127_3256365_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.639e-286 882.0
HKD3_k127_3256365_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000005417 197.0
HKD3_k127_3256365_11 - - - - 0.0000000000000000001943 91.0
HKD3_k127_3256365_2 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 567.0
HKD3_k127_3256365_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 535.0
HKD3_k127_3256365_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 378.0
HKD3_k127_3256365_5 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 321.0
HKD3_k127_3256365_6 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001759 265.0
HKD3_k127_3256365_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004962 248.0
HKD3_k127_3256365_8 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006421 233.0
HKD3_k127_328183_0 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0 1073.0
HKD3_k127_328183_1 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 8.322e-312 972.0
HKD3_k127_328183_10 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 400.0
HKD3_k127_328183_11 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 294.0
HKD3_k127_328183_12 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 286.0
HKD3_k127_328183_13 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003571 263.0
HKD3_k127_328183_14 Protein of unknown function (DUF1467) - - - 0.0000000000000000000000000000000000005491 140.0
HKD3_k127_328183_2 Belongs to the amidase family K01426 - 3.5.1.4 9.1e-307 943.0
HKD3_k127_328183_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 6.062e-297 914.0
HKD3_k127_328183_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.682e-263 818.0
HKD3_k127_328183_5 Periplasmic binding protein domain K11959 - - 2.691e-251 785.0
HKD3_k127_328183_6 Permease family K06901 - - 1.458e-216 679.0
HKD3_k127_328183_7 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 567.0
HKD3_k127_328183_8 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 506.0
HKD3_k127_328183_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 430.0
HKD3_k127_3285680_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 604.0
HKD3_k127_3285680_1 COG2148 Sugar transferases involved in lipopolysaccharide synthesis K03606,K20997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 501.0
HKD3_k127_3285947_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.111e-224 697.0
HKD3_k127_3285947_1 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 8.164e-194 617.0
HKD3_k127_3285947_10 Cupin - - - 0.000000000000000000000000000000000000000000000000000000225 196.0
HKD3_k127_3285947_2 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 563.0
HKD3_k127_3285947_3 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 511.0
HKD3_k127_3285947_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 478.0
HKD3_k127_3285947_5 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 464.0
HKD3_k127_3285947_6 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 415.0
HKD3_k127_3285947_7 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 398.0
HKD3_k127_3285947_8 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 350.0
HKD3_k127_3285947_9 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 318.0
HKD3_k127_3287295_0 Acyclic terpene utilisation family protein AtuA - - - 0.0 1064.0
HKD3_k127_3287295_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 516.0
HKD3_k127_3287295_10 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
HKD3_k127_3287295_11 Bacterial regulatory helix-turn-helix protein, lysR family K02623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001726 259.0
HKD3_k127_3287295_12 Alpha beta hydrolase K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000001178 180.0
HKD3_k127_3287295_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000001549 70.0
HKD3_k127_3287295_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 423.0
HKD3_k127_3287295_3 thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 437.0
HKD3_k127_3287295_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 399.0
HKD3_k127_3287295_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 342.0
HKD3_k127_3287295_6 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
HKD3_k127_3287295_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002188 287.0
HKD3_k127_3287295_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 269.0
HKD3_k127_3287295_9 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000003735 261.0
HKD3_k127_3306097_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.0 1182.0
HKD3_k127_3306097_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 507.0
HKD3_k127_3306097_2 Metal-sensitive transcriptional repressor - - - 0.0000000000000000000000000000000000000000000832 164.0
HKD3_k127_3306097_4 LTXXQ motif family protein - - - 0.0000000000000000000000000001075 123.0
HKD3_k127_3306097_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000001238 123.0
HKD3_k127_3306097_7 Copper binding periplasmic protein CusF - - - 0.000000000000000003616 95.0
HKD3_k127_331306_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1384.0
HKD3_k127_331306_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.589e-307 945.0
HKD3_k127_331306_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 1.238e-219 685.0
HKD3_k127_331306_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000006994 216.0
HKD3_k127_331306_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000000005419 128.0
HKD3_k127_3358025_0 RQC K03654 - 3.6.4.12 5e-324 998.0
HKD3_k127_3358025_1 amine dehydrogenase activity - - - 2.96e-211 660.0
HKD3_k127_3358025_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 567.0
HKD3_k127_3358025_3 de-polymerase K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 499.0
HKD3_k127_3358025_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 482.0
HKD3_k127_3358025_5 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 481.0
HKD3_k127_3358025_6 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 289.0
HKD3_k127_3378015_0 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 575.0
HKD3_k127_3378015_1 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 407.0
HKD3_k127_3378015_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 381.0
HKD3_k127_3378015_3 Ferredoxin, 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 230.0
HKD3_k127_3413695_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 561.0
HKD3_k127_3413695_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 560.0
HKD3_k127_3413695_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 388.0
HKD3_k127_3413695_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 291.0
HKD3_k127_3413695_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000009099 112.0
HKD3_k127_3413695_5 Periplasmic binding protein domain - - - 0.0000000003885 64.0
HKD3_k127_3420490_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 536.0
HKD3_k127_3420490_1 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 482.0
HKD3_k127_3420490_2 Beta-lactamase K18372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 456.0
HKD3_k127_3420490_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K01856 - 5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
HKD3_k127_3420490_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 362.0
HKD3_k127_3420490_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 361.0
HKD3_k127_3420490_6 ATPases associated with a variety of cellular activities K02028,K02029,K09972,K10004 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 295.0
HKD3_k127_3420490_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000003684 245.0
HKD3_k127_3420490_8 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000002075 200.0
HKD3_k127_3420490_9 Luciferase-like monooxygenase - - - 0.0000000001375 61.0
HKD3_k127_343900_0 COG0841 Cation multidrug efflux pump K03296 - - 4.335e-241 752.0
HKD3_k127_343900_1 ABC-type dipeptide transport system periplasmic component K02035 - - 1.848e-227 716.0
HKD3_k127_343900_2 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 503.0
HKD3_k127_343900_3 Uracil-DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
HKD3_k127_343900_4 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006451 269.0
HKD3_k127_343900_5 Belongs to the ompA family - - - 0.0000000000000000000004423 99.0
HKD3_k127_3455585_0 Receptor family ligand binding region - - - 2.809e-224 699.0
HKD3_k127_3455585_1 HI0933-like protein K07007 - - 2.456e-206 656.0
HKD3_k127_3455585_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 562.0
HKD3_k127_3455585_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 492.0
HKD3_k127_3455585_4 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 428.0
HKD3_k127_3455585_5 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 392.0
HKD3_k127_3455585_6 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001067 263.0
HKD3_k127_3455585_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000156 248.0
HKD3_k127_3455585_8 Belongs to the ABC transporter superfamily K01996 GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008144,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:0098655,GO:0098656,GO:1901265,GO:1901363,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000004034 227.0
HKD3_k127_348928_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 8.65e-198 618.0
HKD3_k127_348928_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 334.0
HKD3_k127_348928_3 - - - - 0.00000000000000000000001278 101.0
HKD3_k127_3496080_0 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 400.0
HKD3_k127_3496080_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000006897 113.0
HKD3_k127_3496080_2 Conserved hypothetical protein 698 - - - 0.00000000000000003413 86.0
HKD3_k127_3496080_3 DsrE/DsrF/DrsH-like family - - - 0.00000000005895 63.0
HKD3_k127_3520507_0 Phosphonate ABC transporter K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 508.0
HKD3_k127_3520507_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 446.0
HKD3_k127_3520507_2 Phosphonate ABC transporter K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 444.0
HKD3_k127_3520507_3 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 403.0
HKD3_k127_3520507_4 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 406.0
HKD3_k127_3520507_5 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001115 217.0
HKD3_k127_3520507_6 - - - - 0.0000000000000000000000000000000000000000000000006262 197.0
HKD3_k127_3520507_7 Protein of unknown function (DUF1045) - - - 0.0000000000000000000000000007445 126.0
HKD3_k127_3520507_8 Sodium Bile acid symporter family - - - 0.000000007603 66.0
HKD3_k127_3537418_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.233e-283 877.0
HKD3_k127_3537418_1 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 389.0
HKD3_k127_3537418_2 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
HKD3_k127_3537418_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000001256 171.0
HKD3_k127_3537418_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000009614 124.0
HKD3_k127_3554809_0 Hydantoinase/oxoprolinase - - - 0.0 1177.0
HKD3_k127_3554809_1 Hydantoinase B/oxoprolinase - - - 0.0 1074.0
HKD3_k127_3554809_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 421.0
HKD3_k127_3554809_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 374.0
HKD3_k127_3554809_4 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 279.0
HKD3_k127_3554809_5 long-chain fatty acid transporting porin activity K09806 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000005457 149.0
HKD3_k127_3564358_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 8.672e-251 776.0
HKD3_k127_3564358_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 447.0
HKD3_k127_3564358_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 418.0
HKD3_k127_3564358_3 protein containing LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 404.0
HKD3_k127_3564358_4 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 336.0
HKD3_k127_3564358_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 276.0
HKD3_k127_3564358_6 COG0558 Phosphatidylglycerophosphate synthase - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
HKD3_k127_3564358_8 Type IV leader peptidase family - - - 0.00000001358 59.0
HKD3_k127_3564358_9 pilus assembly protein CpaB K02279 - - 0.000002774 52.0
HKD3_k127_3582063_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 3.795e-317 975.0
HKD3_k127_3582063_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 551.0
HKD3_k127_3582063_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 535.0
HKD3_k127_3582063_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 520.0
HKD3_k127_3582063_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 424.0
HKD3_k127_3582063_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 393.0
HKD3_k127_3582063_6 Iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000001411 224.0
HKD3_k127_3582063_7 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000001433 168.0
HKD3_k127_3621221_0 Biotin carboxylase C-terminal domain - - - 0.0 1853.0
HKD3_k127_3621221_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1225.0
HKD3_k127_3621221_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1051.0
HKD3_k127_3621221_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 562.0
HKD3_k127_3621221_4 COG0655 Multimeric flavodoxin WrbA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 288.0
HKD3_k127_3621221_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000002156 117.0
HKD3_k127_3622997_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 458.0
HKD3_k127_3622997_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 472.0
HKD3_k127_3622997_2 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 401.0
HKD3_k127_3622997_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000874 220.0
HKD3_k127_3622997_4 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000000001313 208.0
HKD3_k127_3622997_5 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HKD3_k127_3654898_0 TonB dependent receptor - - - 6.573e-282 880.0
HKD3_k127_3654898_1 Phosphoesterase family K01114 - 3.1.4.3 2.892e-194 620.0
HKD3_k127_3654898_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
HKD3_k127_3654898_11 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000003819 159.0
HKD3_k127_3654898_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000004345 141.0
HKD3_k127_3654898_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 590.0
HKD3_k127_3654898_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 535.0
HKD3_k127_3654898_4 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 512.0
HKD3_k127_3654898_5 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 531.0
HKD3_k127_3654898_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 431.0
HKD3_k127_3654898_7 transcriptional regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 411.0
HKD3_k127_3654898_8 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 391.0
HKD3_k127_3654898_9 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 363.0
HKD3_k127_3662222_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 596.0
HKD3_k127_3662222_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 377.0
HKD3_k127_3662222_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008098 268.0
HKD3_k127_3698358_0 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 468.0
HKD3_k127_3698358_1 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 443.0
HKD3_k127_3698358_2 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 449.0
HKD3_k127_3698358_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 343.0
HKD3_k127_3703748_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 7.549e-287 891.0
HKD3_k127_3703748_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 6.74e-216 677.0
HKD3_k127_3703748_2 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 599.0
HKD3_k127_3703748_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 547.0
HKD3_k127_3703748_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 448.0
HKD3_k127_3703748_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
HKD3_k127_3788829_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
HKD3_k127_3788829_1 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000000003048 205.0
HKD3_k127_3788829_2 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000002933 194.0
HKD3_k127_3788829_3 Phosphotransferase enzyme family - - - 0.0000000000004905 70.0
HKD3_k127_3794749_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0 1064.0
HKD3_k127_3794749_1 Glycosyltransferase family 28 C-terminal domain - - - 0.0 1033.0
HKD3_k127_3794749_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 295.0
HKD3_k127_3794749_11 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008887 268.0
HKD3_k127_3794749_12 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
HKD3_k127_3794749_13 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000001093 190.0
HKD3_k127_3794749_2 Sulfatase - - - 4.049e-291 903.0
HKD3_k127_3794749_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 2.888e-278 862.0
HKD3_k127_3794749_4 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 497.0
HKD3_k127_3794749_5 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 428.0
HKD3_k127_3794749_6 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 397.0
HKD3_k127_3794749_7 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 368.0
HKD3_k127_3794749_8 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 295.0
HKD3_k127_3794749_9 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 294.0
HKD3_k127_3805094_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 GO:0003674,GO:0003824,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016740,GO:0016741,GO:0016743,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0046944,GO:0051604,GO:0071704,GO:1901564 - 5.796e-234 750.0
HKD3_k127_3805094_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 6.428e-230 718.0
HKD3_k127_3805094_10 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 377.0
HKD3_k127_3805094_11 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 322.0
HKD3_k127_3805094_12 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000004876 236.0
HKD3_k127_3805094_13 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000006843 169.0
HKD3_k127_3805094_14 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000000002129 98.0
HKD3_k127_3805094_15 carbon dioxide binding K04653 - - 0.000000000001982 75.0
HKD3_k127_3805094_16 Protein of unknown function (DUF3141) - - - 0.0000000001452 61.0
HKD3_k127_3805094_2 Major Facilitator Superfamily - - - 7.116e-205 646.0
HKD3_k127_3805094_3 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 8.108e-204 659.0
HKD3_k127_3805094_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 574.0
HKD3_k127_3805094_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 543.0
HKD3_k127_3805094_6 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 528.0
HKD3_k127_3805094_7 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 476.0
HKD3_k127_3805094_8 AIR synthase related protein, N-terminal domain K04655 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 441.0
HKD3_k127_3805094_9 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 379.0
HKD3_k127_3812916_0 Amidase K02433 - 6.3.5.6,6.3.5.7 7.518e-281 887.0
HKD3_k127_3812916_1 Amidase K02433 - 6.3.5.6,6.3.5.7 1.866e-245 792.0
HKD3_k127_3812916_10 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000001735 91.0
HKD3_k127_3812916_11 DNA-dependent DNA replication - - - 0.0000000000000003286 93.0
HKD3_k127_3812916_13 - - - - 0.00000007287 61.0
HKD3_k127_3812916_2 repeat protein - - - 4.373e-237 738.0
HKD3_k127_3812916_3 COG0457 FOG TPR repeat - - - 1.787e-222 716.0
HKD3_k127_3812916_4 NUDIX domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
HKD3_k127_3812916_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 370.0
HKD3_k127_3812916_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 376.0
HKD3_k127_3828850_0 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 529.0
HKD3_k127_3828850_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 523.0
HKD3_k127_3828850_2 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.00000000000000000000000000000000000000000000003736 174.0
HKD3_k127_3828850_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000001793 89.0
HKD3_k127_3828850_4 - - - - 0.000002505 57.0
HKD3_k127_3831138_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.541e-242 774.0
HKD3_k127_3831138_1 Belongs to the binding-protein-dependent transport system permease family K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 555.0
HKD3_k127_3831138_3 ABC transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.00000001034 68.0
HKD3_k127_3837332_0 COG3264 Small-conductance mechanosensitive channel K05802 - - 1.166e-320 1005.0
HKD3_k127_3837332_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 5.765e-204 648.0
HKD3_k127_3837332_2 Alpha beta hydrolase K18092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 544.0
HKD3_k127_3837332_3 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 366.0
HKD3_k127_3837332_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 299.0
HKD3_k127_3837332_5 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000003812 179.0
HKD3_k127_3837332_6 - - - - 0.00000000000000005249 82.0
HKD3_k127_3837332_7 - - - - 0.0000000000000006228 79.0
HKD3_k127_3852596_0 cytochrome c oxidase K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 530.0
HKD3_k127_3852596_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 509.0
HKD3_k127_3852596_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 325.0
HKD3_k127_3852596_3 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
HKD3_k127_3852596_4 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
HKD3_k127_3854959_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0 1011.0
HKD3_k127_3854959_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 2.683e-194 618.0
HKD3_k127_3854959_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001987 261.0
HKD3_k127_3854959_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003217 235.0
HKD3_k127_3854959_4 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.00000000000000000000000000000000000000000000003298 173.0
HKD3_k127_3854959_5 Major facilitator superfamily - - - 0.0000000000000000000000000004668 114.0
HKD3_k127_3862514_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0 1375.0
HKD3_k127_3862514_1 protein involved in outer membrane biogenesis - - - 0.0 1373.0
HKD3_k127_3862514_10 GTP-binding protein TypA K06207 - - 0.00000000000001382 75.0
HKD3_k127_3862514_11 Domain of unknown function (DUF4169) - - - 0.000000004724 69.0
HKD3_k127_3862514_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 516.0
HKD3_k127_3862514_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 465.0
HKD3_k127_3862514_4 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 433.0
HKD3_k127_3862514_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 400.0
HKD3_k127_3862514_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 342.0
HKD3_k127_3862514_7 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 318.0
HKD3_k127_3862514_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000004073 108.0
HKD3_k127_3862514_9 Ribbon-helix-helix domain - - - 0.00000000000000000001059 95.0
HKD3_k127_3865385_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 494.0
HKD3_k127_3865385_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 434.0
HKD3_k127_3865385_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 387.0
HKD3_k127_3865385_3 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000008989 181.0
HKD3_k127_3868683_0 Transposase and inactivated derivatives K07498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 368.0
HKD3_k127_3868683_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 305.0
HKD3_k127_3871177_0 AMP-binding enzyme K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 440.0
HKD3_k127_3871177_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000598 254.0
HKD3_k127_3871177_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000001201 179.0
HKD3_k127_3871177_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000001324 156.0
HKD3_k127_387174_0 Amidohydrolase family - - - 2.016e-197 620.0
HKD3_k127_387174_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 603.0
HKD3_k127_387174_10 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 413.0
HKD3_k127_387174_11 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 370.0
HKD3_k127_387174_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 338.0
HKD3_k127_387174_13 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001927 242.0
HKD3_k127_387174_14 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000573 124.0
HKD3_k127_387174_15 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000446 102.0
HKD3_k127_387174_16 Protein of unknown function (DUF4242) - - - 0.00000000000005549 77.0
HKD3_k127_387174_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 580.0
HKD3_k127_387174_3 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 494.0
HKD3_k127_387174_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 482.0
HKD3_k127_387174_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 466.0
HKD3_k127_387174_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 451.0
HKD3_k127_387174_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 469.0
HKD3_k127_387174_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K22185 - 1.1.1.175 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 431.0
HKD3_k127_387174_9 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 417.0
HKD3_k127_3876160_0 Binding-protein-dependent transport system inner membrane component - - - 8.826e-314 967.0
HKD3_k127_3876160_1 MmgE/PrpD family - - - 1.357e-252 783.0
HKD3_k127_3876160_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 510.0
HKD3_k127_3876160_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 294.0
HKD3_k127_3876160_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.000000000000000000000000277 106.0
HKD3_k127_3919521_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 5.666e-266 822.0
HKD3_k127_3919521_1 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.339e-203 638.0
HKD3_k127_3919521_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 596.0
HKD3_k127_3919521_3 SMP-30/Gluconolaconase/LRE-like region K02352 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 552.0
HKD3_k127_3919521_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 271.0
HKD3_k127_3919521_5 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000003697 223.0
HKD3_k127_3919521_6 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000008492 126.0
HKD3_k127_3919521_7 Sel1-like repeats. - - - 0.0000000000000000000002835 105.0
HKD3_k127_3935455_0 AsmA family K07289,K07290 - - 0.0 1011.0
HKD3_k127_3935455_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 567.0
HKD3_k127_3935455_2 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 520.0
HKD3_k127_3939687_0 - - - - 5.124e-197 617.0
HKD3_k127_3939687_1 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 503.0
HKD3_k127_3939687_2 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 481.0
HKD3_k127_3939687_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 426.0
HKD3_k127_3939687_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 327.0
HKD3_k127_3939687_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000000000000000000001596 231.0
HKD3_k127_3939687_6 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000002463 171.0
HKD3_k127_3939687_7 NUDIX domain - - - 0.00000000000000000000002572 111.0
HKD3_k127_396370_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0 1296.0
HKD3_k127_396370_1 Virulence factor SrfB - - - 0.0 1145.0
HKD3_k127_396370_10 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 444.0
HKD3_k127_396370_11 COX Aromatic Rich Motif K02297 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 388.0
HKD3_k127_396370_12 Cytochrome c oxidase subunit III K02299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 304.0
HKD3_k127_396370_14 transposase activity - - - 0.00000000000000000000000000000006743 143.0
HKD3_k127_396370_15 Prokaryotic Cytochrome C oxidase subunit IV K02300 - - 0.0000000000000000000000000000128 130.0
HKD3_k127_396370_16 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000009861 91.0
HKD3_k127_396370_2 Belongs to the heme-copper respiratory oxidase family - - - 0.0 1122.0
HKD3_k127_396370_3 Putative bacterial virulence factor - - - 0.0 1071.0
HKD3_k127_396370_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.256e-238 739.0
HKD3_k127_396370_5 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 1.557e-213 673.0
HKD3_k127_396370_6 Polysaccharide deacetylase - - - 4.226e-199 620.0
HKD3_k127_396370_7 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 542.0
HKD3_k127_396370_8 Putative bacterial virulence factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 509.0
HKD3_k127_396370_9 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 453.0
HKD3_k127_3993702_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 7.252e-248 770.0
HKD3_k127_3993702_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 9.361e-200 625.0
HKD3_k127_3993702_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 372.0
HKD3_k127_3993702_11 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 353.0
HKD3_k127_3993702_12 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000000000000000000000000000000000000000003003 205.0
HKD3_k127_3993702_13 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000000000000000000000000000001065 208.0
HKD3_k127_3993702_14 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000008241 189.0
HKD3_k127_3993702_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000000000000008465 140.0
HKD3_k127_3993702_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 561.0
HKD3_k127_3993702_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 518.0
HKD3_k127_3993702_4 restriction endodeoxyribonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 505.0
HKD3_k127_3993702_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
HKD3_k127_3993702_6 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
HKD3_k127_3993702_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 385.0
HKD3_k127_3993702_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 385.0
HKD3_k127_3993702_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 395.0
HKD3_k127_3996283_0 Carbon-nitrogen hydrolase - - - 1.903e-195 611.0
HKD3_k127_3996283_1 GDP-mannose 4,6 dehydratase K18981 - 1.1.1.203 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 487.0
HKD3_k127_3996283_2 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 429.0
HKD3_k127_4048279_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.572e-237 740.0
HKD3_k127_4048279_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.047e-226 711.0
HKD3_k127_4048279_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000001985 201.0
HKD3_k127_4048279_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002132 147.0
HKD3_k127_4048279_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000000000008084 111.0
HKD3_k127_4048279_13 - - - - 0.000000000005925 70.0
HKD3_k127_4048279_2 COG1530 Ribonucleases G and E K08300,K08301 - 3.1.26.12 2.519e-215 677.0
HKD3_k127_4048279_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 417.0
HKD3_k127_4048279_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 352.0
HKD3_k127_4048279_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 302.0
HKD3_k127_4048279_6 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001191 259.0
HKD3_k127_4048279_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002399 252.0
HKD3_k127_4048279_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002722 246.0
HKD3_k127_4048279_9 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000000000000000000000000000009142 232.0
HKD3_k127_4049290_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 607.0
HKD3_k127_4049290_1 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000000000000000000000008397 205.0
HKD3_k127_4049290_2 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001889 205.0
HKD3_k127_4049290_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000003576 195.0
HKD3_k127_4049290_4 - - - - 0.00000000000000000000000000000000000000000002536 166.0
HKD3_k127_4049290_5 AMP-dependent synthetase K01897 - 6.2.1.3 0.00000002525 55.0
HKD3_k127_4065191_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 551.0
HKD3_k127_4065191_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 436.0
HKD3_k127_4065191_2 Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 383.0
HKD3_k127_408694_0 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 6.601e-274 867.0
HKD3_k127_408694_1 Sulfate permease family K03321 - - 2.88e-249 779.0
HKD3_k127_408694_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000002088 226.0
HKD3_k127_408694_11 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000002126 196.0
HKD3_k127_408694_12 VIT family - - - 0.000000000000000000000000000000000000000000000000000522 191.0
HKD3_k127_408694_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001405 174.0
HKD3_k127_408694_16 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0001665 45.0
HKD3_k127_408694_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 437.0
HKD3_k127_408694_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 419.0
HKD3_k127_408694_4 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 407.0
HKD3_k127_408694_5 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 334.0
HKD3_k127_408694_6 Poly(3-hydroxyalkanoate) synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 309.0
HKD3_k127_408694_7 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 291.0
HKD3_k127_408694_8 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000001938 234.0
HKD3_k127_408694_9 [2Fe-2S] binding domain K18029 - 1.17.2.1 0.00000000000000000000000000000000000000000000000000000000000001034 218.0
HKD3_k127_4128771_0 - - - - 3.136e-206 647.0
HKD3_k127_4128771_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 366.0
HKD3_k127_4128771_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003957 267.0
HKD3_k127_4138469_0 III protein, CoA-transferase family K07749 - 2.8.3.16 6.049e-214 669.0
HKD3_k127_4138469_1 OpgC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 587.0
HKD3_k127_4138469_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 542.0
HKD3_k127_4138469_3 COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 474.0
HKD3_k127_4138469_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000004895 178.0
HKD3_k127_4148676_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 9.01e-226 702.0
HKD3_k127_4148676_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 506.0
HKD3_k127_4148676_2 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 481.0
HKD3_k127_4148676_3 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
HKD3_k127_4148676_4 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 294.0
HKD3_k127_4148676_5 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
HKD3_k127_4148676_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000002919 57.0
HKD3_k127_4167172_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.503e-314 968.0
HKD3_k127_4167172_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 6.813e-283 876.0
HKD3_k127_4167172_10 integral membrane protein - - - 0.000000000000000000000003687 109.0
HKD3_k127_4167172_11 EamA-like transporter family - - - 0.0000000000008207 80.0
HKD3_k127_4167172_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 5.503e-207 646.0
HKD3_k127_4167172_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 512.0
HKD3_k127_4167172_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00038 - 1.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 458.0
HKD3_k127_4167172_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
HKD3_k127_4167172_6 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000009394 200.0
HKD3_k127_4167172_7 PFAM Dimethylmenaquinone methyltransferase - - - 0.00000000000000000000000000000000001398 149.0
HKD3_k127_4167172_8 - - - - 0.00000000000000000000000000000000002956 139.0
HKD3_k127_4167172_9 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000423 126.0
HKD3_k127_4181287_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.163e-277 859.0
HKD3_k127_4181287_1 Heparinase II/III-like protein - - - 1.839e-205 648.0
HKD3_k127_4181287_10 ClpX C4-type zinc finger - - - 0.00000000000000000000000604 105.0
HKD3_k127_4181287_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 465.0
HKD3_k127_4181287_3 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 327.0
HKD3_k127_4181287_4 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 261.0
HKD3_k127_4181287_5 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003435 259.0
HKD3_k127_4181287_6 Cupin domain - - - 0.00000000000000000000000000000000000000000002443 167.0
HKD3_k127_4181287_7 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000003717 166.0
HKD3_k127_4181287_9 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000000000006643 118.0
HKD3_k127_4183362_0 Penicillin amidase K01434 - 3.5.1.11 2.7e-322 991.0
HKD3_k127_4183362_1 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 535.0
HKD3_k127_4183362_2 Enoyl-CoA hydratase/isomerase K15312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 381.0
HKD3_k127_4196280_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 514.0
HKD3_k127_4196280_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
HKD3_k127_4196280_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 381.0
HKD3_k127_4196280_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
HKD3_k127_4196280_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000008351 221.0
HKD3_k127_41963_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 512.0
HKD3_k127_41963_1 Alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 479.0
HKD3_k127_41963_2 cell division K05803 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 368.0
HKD3_k127_4227107_0 protein involved in outer membrane biogenesis - - - 0.0 1215.0
HKD3_k127_4227107_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.676e-247 772.0
HKD3_k127_4227107_2 mandelate racemase muconate lactonizing - - - 3.147e-208 651.0
HKD3_k127_4227107_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 492.0
HKD3_k127_4227107_4 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 379.0
HKD3_k127_4227178_0 Amidase K01426 - 3.5.1.4 4.194e-255 816.0
HKD3_k127_4227178_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.59e-201 632.0
HKD3_k127_4227178_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000001316 95.0
HKD3_k127_4227178_11 Amidohydrolase K07045 - - 0.0005362 51.0
HKD3_k127_4227178_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 595.0
HKD3_k127_4227178_3 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 505.0
HKD3_k127_4227178_4 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 440.0
HKD3_k127_4227178_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 443.0
HKD3_k127_4227178_6 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 436.0
HKD3_k127_4227178_7 Methyladenine glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 396.0
HKD3_k127_4227178_8 PFAM Asp Glu hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
HKD3_k127_4227178_9 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD3_k127_4259635_0 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.369e-199 628.0
HKD3_k127_4259635_1 FAD linked oxidases, C-terminal domain K18930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 494.0
HKD3_k127_4259635_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 310.0
HKD3_k127_4259635_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
HKD3_k127_4259635_4 chaperone-mediated protein folding - GO:0003674,GO:0003756,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016043,GO:0016787,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0022607,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043163,GO:0043165,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044464,GO:0045229,GO:0046872,GO:0051603,GO:0061024,GO:0061077,GO:0070011,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009627 273.0
HKD3_k127_4259635_5 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000009875 87.0
HKD3_k127_4273129_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1232.0
HKD3_k127_4273129_1 aminopeptidase K01262 - 3.4.11.9 0.0 1081.0
HKD3_k127_4273129_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
HKD3_k127_4273129_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 559.0
HKD3_k127_4273129_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 452.0
HKD3_k127_4273129_5 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
HKD3_k127_4273129_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 289.0
HKD3_k127_4298457_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0 1102.0
HKD3_k127_4298457_1 Protein tyrosine kinase - - - 2.049e-272 850.0
HKD3_k127_4298457_10 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 464.0
HKD3_k127_4298457_11 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 444.0
HKD3_k127_4298457_12 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 394.0
HKD3_k127_4298457_13 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 359.0
HKD3_k127_4298457_14 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 352.0
HKD3_k127_4298457_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 322.0
HKD3_k127_4298457_16 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 285.0
HKD3_k127_4298457_17 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001444 266.0
HKD3_k127_4298457_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000171 246.0
HKD3_k127_4298457_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000294 221.0
HKD3_k127_4298457_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.198e-265 820.0
HKD3_k127_4298457_20 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000008161 221.0
HKD3_k127_4298457_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000000006449 208.0
HKD3_k127_4298457_23 acetyltransferase K06966 - 3.2.2.10 0.000000000000000000000000000000000000005496 151.0
HKD3_k127_4298457_25 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002979 111.0
HKD3_k127_4298457_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000004638 98.0
HKD3_k127_4298457_3 Cytochrome P450 - - - 2.504e-221 693.0
HKD3_k127_4298457_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 8.153e-214 665.0
HKD3_k127_4298457_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
HKD3_k127_4298457_6 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 519.0
HKD3_k127_4298457_7 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 538.0
HKD3_k127_4298457_8 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 505.0
HKD3_k127_4298457_9 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 494.0
HKD3_k127_4301255_0 ABC transporter transmembrane region K02021 - - 0.0 1551.0
HKD3_k127_4301255_1 COG0708 Exonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 509.0
HKD3_k127_4301255_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 462.0
HKD3_k127_4301255_3 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 326.0
HKD3_k127_4301255_4 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 280.0
HKD3_k127_4301255_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005195 245.0
HKD3_k127_4301255_6 Transglycosylase associated protein - - - 0.0000000000000000000000000000001298 124.0
HKD3_k127_4301255_7 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000005608 110.0
HKD3_k127_4303232_0 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 GO:0003674,GO:0003824,GO:0004497,GO:0006139,GO:0006206,GO:0006208,GO:0006210,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0017144,GO:0019740,GO:0019859,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0052614,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 532.0
HKD3_k127_4303232_1 ABC transporter substrate-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 529.0
HKD3_k127_4303232_2 In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 K09020 - 3.5.1.110 0.00000000000000000000000000000000000000000000000000000000000000001953 233.0
HKD3_k127_4307339_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.025e-288 891.0
HKD3_k127_4307339_1 N-terminal domain of oxidoreductase K07119 - - 5.092e-196 618.0
HKD3_k127_4307339_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 473.0
HKD3_k127_4307339_3 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 415.0
HKD3_k127_4311435_0 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 7.463e-288 889.0
HKD3_k127_4311435_1 Luciferase-like monooxygenase - - - 6.005e-231 733.0
HKD3_k127_4311435_10 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000008835 158.0
HKD3_k127_4311435_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000005176 145.0
HKD3_k127_4311435_2 Putative serine dehydratase domain - - - 9.018e-215 682.0
HKD3_k127_4311435_3 Flavoprotein involved in K transport - - - 4.184e-208 652.0
HKD3_k127_4311435_4 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 509.0
HKD3_k127_4311435_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 366.0
HKD3_k127_4311435_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000375 250.0
HKD3_k127_4311435_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000004117 201.0
HKD3_k127_4311435_9 - - - - 0.00000000000000000000000000000000000000000009715 173.0
HKD3_k127_4324242_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 995.0
HKD3_k127_4324242_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 564.0
HKD3_k127_4348244_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1231.0
HKD3_k127_4348244_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.504e-281 865.0
HKD3_k127_4348244_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.532e-210 654.0
HKD3_k127_4348244_3 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 354.0
HKD3_k127_4348244_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 332.0
HKD3_k127_4348244_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003825 217.0
HKD3_k127_4403133_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1300.0
HKD3_k127_4403133_1 FAD dependent oxidoreductase - - - 6.133e-225 703.0
HKD3_k127_4403133_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 578.0
HKD3_k127_4403133_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 460.0
HKD3_k127_4403133_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 387.0
HKD3_k127_4403133_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001838 274.0
HKD3_k127_4403133_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000002395 218.0
HKD3_k127_4403133_7 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000007235 220.0
HKD3_k127_4403133_8 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
HKD3_k127_4403133_9 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000000000000002463 147.0
HKD3_k127_4408663_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 6.733e-196 616.0
HKD3_k127_4408663_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 373.0
HKD3_k127_4408663_2 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 352.0
HKD3_k127_441860_0 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.0 1111.0
HKD3_k127_441860_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 353.0
HKD3_k127_441860_2 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 285.0
HKD3_k127_441860_3 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000000000000000157 220.0
HKD3_k127_4422613_0 Retinal pigment epithelial membrane protein - - - 1.57e-236 743.0
HKD3_k127_4422613_1 metal-dependent hydrolase of the TIM-barrel fold - - - 7.466e-234 726.0
HKD3_k127_4422613_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 498.0
HKD3_k127_4422613_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 467.0
HKD3_k127_4422613_4 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 429.0
HKD3_k127_4422613_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 401.0
HKD3_k127_4422613_6 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HKD3_k127_4422613_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004689 265.0
HKD3_k127_4422613_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
HKD3_k127_4422613_9 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000000000000000000000000000001451 143.0
HKD3_k127_4436354_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.598e-296 915.0
HKD3_k127_4436354_1 Putative serine dehydratase domain - - - 6.759e-213 664.0
HKD3_k127_4436354_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 444.0
HKD3_k127_4436354_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 461.0
HKD3_k127_4436354_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 317.0
HKD3_k127_4436354_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
HKD3_k127_4436354_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000003145 137.0
HKD3_k127_4440578_0 malic enzyme K00029 - 1.1.1.40 3.115e-204 638.0
HKD3_k127_4440578_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 427.0
HKD3_k127_4460796_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 1.551e-305 959.0
HKD3_k127_4460796_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 5.126e-292 900.0
HKD3_k127_4460796_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.126e-226 714.0
HKD3_k127_4460796_4 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000000000000005473 168.0
HKD3_k127_4460796_6 - - - - 0.00000000000000000000000001023 116.0
HKD3_k127_4460796_7 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000001603 79.0
HKD3_k127_4487591_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00612 - - 0.0 1137.0
HKD3_k127_4487591_1 Carboxyl transferase domain - - - 1.232e-233 734.0
HKD3_k127_4487591_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 307.0
HKD3_k127_4487591_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 304.0
HKD3_k127_4487591_4 hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
HKD3_k127_4487591_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005724 243.0
HKD3_k127_4487591_6 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000005194 177.0
HKD3_k127_4487591_7 - - - - 0.000000000000000002687 93.0
HKD3_k127_4492890_0 Sulfatase K01130 - 3.1.6.1 4.271e-317 992.0
HKD3_k127_4492890_1 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 1.653e-310 972.0
HKD3_k127_4492890_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K14446 - 1.3.1.85 2.137e-284 876.0
HKD3_k127_4492890_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 554.0
HKD3_k127_4492890_4 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 495.0
HKD3_k127_4492890_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 444.0
HKD3_k127_4492890_6 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 426.0
HKD3_k127_4578236_0 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 0.0 1156.0
HKD3_k127_4578236_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 6.126e-286 884.0
HKD3_k127_4578236_10 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 438.0
HKD3_k127_4578236_11 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 383.0
HKD3_k127_4578236_12 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 372.0
HKD3_k127_4578236_13 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 318.0
HKD3_k127_4578236_15 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
HKD3_k127_4578236_16 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
HKD3_k127_4578236_17 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000001383 177.0
HKD3_k127_4578236_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000001855 175.0
HKD3_k127_4578236_19 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000000000007005 169.0
HKD3_k127_4578236_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.289e-285 881.0
HKD3_k127_4578236_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 7.312e-264 816.0
HKD3_k127_4578236_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 9.122e-229 715.0
HKD3_k127_4578236_5 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 7.532e-215 675.0
HKD3_k127_4578236_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 1.253e-199 623.0
HKD3_k127_4578236_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 600.0
HKD3_k127_4578236_8 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 535.0
HKD3_k127_4578236_9 Amino-transferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 506.0
HKD3_k127_4583428_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1092.0
HKD3_k127_4583428_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.091e-229 715.0
HKD3_k127_4583428_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 6.924e-209 655.0
HKD3_k127_4583428_3 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 597.0
HKD3_k127_4583428_4 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000002122 156.0
HKD3_k127_4584092_0 COG0841 Cation multidrug efflux pump K18138 - - 0.0 1701.0
HKD3_k127_4584092_1 CoA-transferase family III - - - 6.765e-231 722.0
HKD3_k127_4584092_2 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 499.0
HKD3_k127_4584092_3 the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 435.0
HKD3_k127_4584092_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 422.0
HKD3_k127_4584092_5 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000003918 87.0
HKD3_k127_4612607_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 3.125e-318 981.0
HKD3_k127_4612607_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 3.857e-204 640.0
HKD3_k127_4612607_2 peptidyl-tyrosine sulfation - - - 2.89e-196 621.0
HKD3_k127_4612607_3 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 579.0
HKD3_k127_4612607_4 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 576.0
HKD3_k127_4612607_5 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 512.0
HKD3_k127_4612607_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
HKD3_k127_4612607_7 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000006224 125.0
HKD3_k127_4612607_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000002909 62.0
HKD3_k127_4612607_9 Major Facilitator Superfamily K03446 - - 0.0003341 44.0
HKD3_k127_4623213_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 544.0
HKD3_k127_4623213_1 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 475.0
HKD3_k127_4623213_2 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 385.0
HKD3_k127_4641498_0 Glycosyl hydrolases family 15 - - - 0.0 1050.0
HKD3_k127_4641498_1 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 395.0
HKD3_k127_4686677_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 501.0
HKD3_k127_4686677_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 469.0
HKD3_k127_4686677_2 Bacterial periplasmic substrate-binding proteins K10018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 466.0
HKD3_k127_4686677_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 335.0
HKD3_k127_4686677_4 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
HKD3_k127_4686677_5 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000000000000000000000000000000000000000000000000000000000008406 214.0
HKD3_k127_4704682_0 Threonine synthase K01733 - 4.2.3.1 3.115e-268 834.0
HKD3_k127_4704682_1 Belongs to the peptidase M16 family - - - 1.891e-252 781.0
HKD3_k127_4704682_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 2.377e-201 646.0
HKD3_k127_4704682_3 Aspartyl/Asparaginyl beta-hydroxylase K12979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 475.0
HKD3_k127_4704682_4 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 439.0
HKD3_k127_4704682_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 376.0
HKD3_k127_4704682_6 Catechol dioxygenase N terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 337.0
HKD3_k127_4704682_7 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000000000000000000000000000004749 196.0
HKD3_k127_4704682_8 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000000000000000000001122 179.0
HKD3_k127_471992_0 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0 1119.0
HKD3_k127_471992_1 malic enzyme K00029 - 1.1.1.40 1.172e-264 820.0
HKD3_k127_471992_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 426.0
HKD3_k127_471992_3 - - - - 0.0000000000000000000000000000000000000000000005616 173.0
HKD3_k127_4724445_0 CoA-transferase family III K01796 - 5.1.99.4 4.114e-231 720.0
HKD3_k127_4724445_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 391.0
HKD3_k127_4724445_2 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
HKD3_k127_474505_0 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 602.0
HKD3_k127_474505_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 537.0
HKD3_k127_474505_2 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 549.0
HKD3_k127_474505_3 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 488.0
HKD3_k127_474505_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 485.0
HKD3_k127_474505_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000002062 221.0
HKD3_k127_474505_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000005197 199.0
HKD3_k127_474505_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000004407 183.0
HKD3_k127_4749184_0 Transmembrane secretion effector - - - 9.876e-220 690.0
HKD3_k127_4749184_1 ammonia monooxygenase K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 586.0
HKD3_k127_4749184_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 507.0
HKD3_k127_4749184_3 Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 511.0
HKD3_k127_4749184_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 440.0
HKD3_k127_4749184_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 391.0
HKD3_k127_4749184_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 374.0
HKD3_k127_4749184_7 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001012 260.0
HKD3_k127_4749184_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001448 255.0
HKD3_k127_4749184_9 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000000000002947 196.0
HKD3_k127_4760703_0 Receptor family ligand binding region - - - 3.665e-242 754.0
HKD3_k127_4760703_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 537.0
HKD3_k127_4760703_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 511.0
HKD3_k127_4760703_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 436.0
HKD3_k127_4760703_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 389.0
HKD3_k127_4760703_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 399.0
HKD3_k127_4760703_6 COG2015, Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 351.0
HKD3_k127_481953_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 415.0
HKD3_k127_481953_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 400.0
HKD3_k127_481953_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001879 264.0
HKD3_k127_481953_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
HKD3_k127_481953_4 TIR domain - - - 0.000000000000000000000000000000000000000000001822 181.0
HKD3_k127_482573_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1105.0
HKD3_k127_482573_1 Cys/Met metabolism PLP-dependent enzyme K00652,K00654 - 2.3.1.47,2.3.1.50 6.257e-243 754.0
HKD3_k127_482573_2 pfam abc K01990,K01992,K09695 - - 1.501e-195 631.0
HKD3_k127_482573_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 378.0
HKD3_k127_482573_4 Abc-type multidrug transport system, permease component K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 357.0
HKD3_k127_482573_5 secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 287.0
HKD3_k127_482573_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000001905 246.0
HKD3_k127_482573_7 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
HKD3_k127_482573_8 Phosphopantetheine attachment site - - - 0.0000000000000000000000001285 106.0
HKD3_k127_482573_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.0000001552 59.0
HKD3_k127_4846049_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 539.0
HKD3_k127_4846049_1 Ca2 -binding protein (EF-Hand superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 495.0
HKD3_k127_4846049_2 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 429.0
HKD3_k127_4846049_3 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 414.0
HKD3_k127_4847280_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1842.0
HKD3_k127_4847280_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 4.164e-281 874.0
HKD3_k127_4847280_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000004838 241.0
HKD3_k127_4847280_13 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 0.000000000000000000000000000000001653 130.0
HKD3_k127_4847280_14 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000002 52.0
HKD3_k127_4847280_2 AAA domain K07028 - - 6.102e-227 718.0
HKD3_k127_4847280_3 Major Facilitator Superfamily - - - 8.927e-217 679.0
HKD3_k127_4847280_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.241e-214 670.0
HKD3_k127_4847280_5 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 541.0
HKD3_k127_4847280_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 370.0
HKD3_k127_4847280_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 343.0
HKD3_k127_4847280_8 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 316.0
HKD3_k127_4847280_9 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001059 252.0
HKD3_k127_4853078_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596 - 4.1.1.64 1.827e-239 756.0
HKD3_k127_4853078_1 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 518.0
HKD3_k127_4853078_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 354.0
HKD3_k127_4853078_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004677 269.0
HKD3_k127_4893309_0 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 602.0
HKD3_k127_4893309_1 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 566.0
HKD3_k127_4893309_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 527.0
HKD3_k127_4893309_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 496.0
HKD3_k127_4893309_4 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009309 271.0
HKD3_k127_4893309_5 ABC-type nitrate sulfonate bicarbonate transport system permease component - - - 0.000000000000000000000000000000000000000000000000000000000000005217 232.0
HKD3_k127_4893309_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000003194 93.0
HKD3_k127_4893309_7 NMT1-like family K02051 - - 0.0000000000000000007817 93.0
HKD3_k127_4902589_0 Homospermidine synthase K00808 - 2.5.1.44 3.767e-269 833.0
HKD3_k127_4902589_1 Bacterial extracellular solute-binding protein K05813 - - 1.272e-255 792.0
HKD3_k127_4902589_10 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 398.0
HKD3_k127_4902589_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 361.0
HKD3_k127_4902589_12 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
HKD3_k127_4902589_13 Invasion associated locus B (IalB) protein - - - 0.0000000000000000000000000000000000000000000000009111 182.0
HKD3_k127_4902589_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000003181 67.0
HKD3_k127_4902589_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 1.02e-237 736.0
HKD3_k127_4902589_3 acetyltransferase - - - 1.341e-219 684.0
HKD3_k127_4902589_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816 - 3.6.3.20 9.27e-204 637.0
HKD3_k127_4902589_5 Transmembrane secretion effector - - - 1.712e-200 650.0
HKD3_k127_4902589_6 Autotransporter beta-domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 571.0
HKD3_k127_4902589_7 Binding-protein-dependent transport system inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 523.0
HKD3_k127_4902589_8 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 471.0
HKD3_k127_4902589_9 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 419.0
HKD3_k127_4908697_0 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 4.222e-221 689.0
HKD3_k127_4908697_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 589.0
HKD3_k127_4908697_10 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000001425 164.0
HKD3_k127_4908697_12 Protein conserved in bacteria - - - 0.0000005795 59.0
HKD3_k127_4908697_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 516.0
HKD3_k127_4908697_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 491.0
HKD3_k127_4908697_4 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 438.0
HKD3_k127_4908697_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 366.0
HKD3_k127_4908697_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 310.0
HKD3_k127_4908697_7 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009054 287.0
HKD3_k127_4908697_8 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001053 223.0
HKD3_k127_4914940_0 ATPases associated with a variety of cellular activities K06147 - - 1.98e-280 874.0
HKD3_k127_4914940_1 Glutathionylspermidine synthase preATP-grasp - - - 1.608e-231 722.0
HKD3_k127_4914940_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 572.0
HKD3_k127_4914940_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 536.0
HKD3_k127_4914940_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 523.0
HKD3_k127_4921549_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 4.152e-212 673.0
HKD3_k127_4921549_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 570.0
HKD3_k127_4921549_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 487.0
HKD3_k127_4921549_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000007066 204.0
HKD3_k127_4925422_0 amino acid K01999 - - 7.589e-229 716.0
HKD3_k127_4925422_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 8.033e-201 630.0
HKD3_k127_4925422_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 546.0
HKD3_k127_4925422_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 477.0
HKD3_k127_4925422_4 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 473.0
HKD3_k127_4925422_5 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 436.0
HKD3_k127_4925422_6 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 307.0
HKD3_k127_4929792_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 541.0
HKD3_k127_4929792_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 461.0
HKD3_k127_4929792_2 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 413.0
HKD3_k127_4929792_3 Belongs to the enoyl-CoA hydratase isomerase family K08299,K16426 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
HKD3_k127_4929792_4 cyclic nucleotide binding K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 394.0
HKD3_k127_4929792_5 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 356.0
HKD3_k127_4929792_6 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001052 272.0
HKD3_k127_4929792_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000005579 235.0
HKD3_k127_4929792_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000001202 174.0
HKD3_k127_4933775_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 8.183e-257 809.0
HKD3_k127_4933775_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.439e-236 743.0
HKD3_k127_4933775_2 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HKD3_k127_4933775_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 329.0
HKD3_k127_4933775_4 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 325.0
HKD3_k127_4933775_5 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 291.0
HKD3_k127_4933775_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 278.0
HKD3_k127_4933775_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002226 289.0
HKD3_k127_4962310_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1338.0
HKD3_k127_4983923_0 COG1960 Acyl-CoA dehydrogenases - - - 1.177e-215 678.0
HKD3_k127_4983923_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 313.0
HKD3_k127_4983923_2 EamA-like transporter family - - - 0.000000000000000000000000000000000005791 139.0
HKD3_k127_4983923_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000001705 108.0
HKD3_k127_5029902_0 Belongs to the TPP enzyme family - - - 1.542e-275 856.0
HKD3_k127_5029902_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 532.0
HKD3_k127_5029902_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD3_k127_5029902_3 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000000000000000000000000000005655 229.0
HKD3_k127_5031107_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1107.0
HKD3_k127_5031107_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.839e-265 822.0
HKD3_k127_5031107_2 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 4.125e-205 649.0
HKD3_k127_5031107_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 514.0
HKD3_k127_5031107_4 2-oxohepta-3-ene-1,7-dioic acid hydratase K01617,K02509 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 362.0
HKD3_k127_5031107_5 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000006566 185.0
HKD3_k127_5031107_7 transcriptional regulator - - - 0.000000000000000000004531 104.0
HKD3_k127_5031107_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000004063 70.0
HKD3_k127_5038754_0 DNA ligase K01971 - 6.5.1.1 0.0 1272.0
HKD3_k127_5038754_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
HKD3_k127_5038754_2 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22316 - 3.1.26.4,3.1.3.3,3.1.3.73,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000006018 247.0
HKD3_k127_5045270_0 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 1.203e-285 884.0
HKD3_k127_5045270_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 338.0
HKD3_k127_5045270_2 Peptidase M15A K03791 - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
HKD3_k127_5045270_3 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000002238 97.0
HKD3_k127_507074_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.754e-252 790.0
HKD3_k127_507074_1 Adenylate cyclase K01768 - 4.6.1.1 2.545e-211 667.0
HKD3_k127_507074_2 Adenylate cyclase K01768 - 4.6.1.1 3.435e-196 643.0
HKD3_k127_507074_3 Transglutaminase - - - 2.551e-195 632.0
HKD3_k127_507074_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 609.0
HKD3_k127_507074_5 HIUase/Transthyretin family K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 484.0
HKD3_k127_508636_0 Glycosyl transferase 4-like domain K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 608.0
HKD3_k127_508636_1 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 546.0
HKD3_k127_508636_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 474.0
HKD3_k127_5111964_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
HKD3_k127_5111964_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000001684 180.0
HKD3_k127_5111964_2 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000004575 176.0
HKD3_k127_5111964_3 - - - - 0.00000001414 63.0
HKD3_k127_5119317_0 His Kinase A (phosphoacceptor) domain - - - 6.083e-250 782.0
HKD3_k127_5119317_1 Histidine kinase - - - 3.311e-211 684.0
HKD3_k127_5119317_12 TadE-like protein - - - 0.00001073 53.0
HKD3_k127_5119317_13 PFAM TadE family protein - - - 0.000314 51.0
HKD3_k127_5119317_14 Putative Flp pilus-assembly TadE/G-like - - - 0.0004528 48.0
HKD3_k127_5119317_2 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 420.0
HKD3_k127_5119317_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 362.0
HKD3_k127_5119317_4 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 297.0
HKD3_k127_5119317_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001815 230.0
HKD3_k127_5119317_8 CsbD-like - - - 0.000000000000000000000000000001669 122.0
HKD3_k127_5119317_9 Tetratricopeptide repeat - - - 0.000000000000000000000000157 116.0
HKD3_k127_5122967_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 8.042e-294 904.0
HKD3_k127_5122967_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.85e-254 805.0
HKD3_k127_5122967_10 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003775 239.0
HKD3_k127_5122967_11 PFAM NUDIX hydrolase K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000002003 237.0
HKD3_k127_5122967_12 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000009117 209.0
HKD3_k127_5122967_13 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000002034 196.0
HKD3_k127_5122967_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000001103 173.0
HKD3_k127_5122967_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000002283 161.0
HKD3_k127_5122967_16 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000000000000005908 162.0
HKD3_k127_5122967_17 - - - - 0.0000000000000000000000003802 106.0
HKD3_k127_5122967_19 Protein conserved in bacteria K09914 - - 0.000008878 56.0
HKD3_k127_5122967_2 Vacuole effluxer Atg22 like K06902 - - 1.092e-247 771.0
HKD3_k127_5122967_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 526.0
HKD3_k127_5122967_4 Haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 469.0
HKD3_k127_5122967_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 426.0
HKD3_k127_5122967_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 397.0
HKD3_k127_5122967_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
HKD3_k127_5122967_8 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 359.0
HKD3_k127_5122967_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 282.0
HKD3_k127_5129689_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 456.0
HKD3_k127_5129689_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
HKD3_k127_5129689_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 400.0
HKD3_k127_5129689_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 318.0
HKD3_k127_5129689_4 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002089 223.0
HKD3_k127_5146206_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1300.0
HKD3_k127_5146206_1 CoA-transferase family III - - - 6.561e-218 690.0
HKD3_k127_5146206_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
HKD3_k127_5146206_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
HKD3_k127_5146206_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 541.0
HKD3_k127_5146206_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 477.0
HKD3_k127_5146206_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003874 271.0
HKD3_k127_5146206_7 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
HKD3_k127_5146206_8 Intracellular septation protein A - - - 0.0000000000000000000000000000000000000000000000000003992 188.0
HKD3_k127_5163128_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 1.201e-198 636.0
HKD3_k127_5163128_1 IS66 Orf2 K07484 - - 0.000000000000000000000000000000000000000000000000006447 188.0
HKD3_k127_5163128_2 Transposase K07483 - - 0.00000000000000000758 87.0
HKD3_k127_5183783_0 Tfp pilus assembly protein K02655 - - 0.0000000000000000000000000000000002978 136.0
HKD3_k127_5183783_1 Prokaryotic N-terminal methylation motif K08084 - - 0.00000000000000000000000000007246 128.0
HKD3_k127_5183783_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000009535 85.0
HKD3_k127_5195769_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
HKD3_k127_5195769_1 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
HKD3_k127_5195769_2 oxidoreductase - - - 0.0000000000000585 72.0
HKD3_k127_5200464_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0 1051.0
HKD3_k127_5200464_1 Zn-dependent proteases and their inactivated homologs K03592 - - 1.79e-247 770.0
HKD3_k127_5200464_2 L-carnitine dehydratase bile acid-inducible protein - - - 7.845e-240 744.0
HKD3_k127_5200464_3 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 453.0
HKD3_k127_5200464_4 - - - - 0.00000000000000000004347 92.0
HKD3_k127_5213285_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1125.0
HKD3_k127_5213285_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.178e-277 859.0
HKD3_k127_5213285_2 Belongs to the ABC transporter superfamily - - - 1.074e-199 625.0
HKD3_k127_5213285_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 570.0
HKD3_k127_5213285_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 549.0
HKD3_k127_5213285_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 526.0
HKD3_k127_5213285_6 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 433.0
HKD3_k127_5213285_7 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HKD3_k127_5213285_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004294 247.0
HKD3_k127_5213285_9 PFAM conserved - - - 0.0000000000001456 75.0
HKD3_k127_5216222_0 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
HKD3_k127_5216222_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004745 245.0
HKD3_k127_5229224_0 ABC transporter transmembrane region - - - 0.0 1930.0
HKD3_k127_5229224_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1136.0
HKD3_k127_5229224_10 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000001209 156.0
HKD3_k127_5229224_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000336 151.0
HKD3_k127_5229224_12 - - - - 0.000000000000000000000000000000000186 134.0
HKD3_k127_5229224_13 transposase activity - - - 0.000000000000000000000000000004088 129.0
HKD3_k127_5229224_14 Transcriptional regulator - - - 0.0000000000000000000000003519 108.0
HKD3_k127_5229224_15 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000003467 63.0
HKD3_k127_5229224_16 Cysteine dioxygenase type I - - - 0.00000001803 58.0
HKD3_k127_5229224_17 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000002101 55.0
HKD3_k127_5229224_2 56kDa selenium binding protein (SBP56) K17285 - - 1.18e-289 891.0
HKD3_k127_5229224_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 593.0
HKD3_k127_5229224_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD3_k127_5229224_5 PFAM beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 377.0
HKD3_k127_5229224_6 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 297.0
HKD3_k127_5229224_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002414 282.0
HKD3_k127_5229224_8 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000003194 232.0
HKD3_k127_5229224_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003894 212.0
HKD3_k127_5229628_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0 1023.0
HKD3_k127_5229628_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 1.865e-255 807.0
HKD3_k127_5229628_10 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000973 256.0
HKD3_k127_5229628_11 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001701 218.0
HKD3_k127_5229628_12 LysE type translocator - - - 0.0000000000000000000000000000000000000000000003386 191.0
HKD3_k127_5229628_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000003824 164.0
HKD3_k127_5229628_14 Ndr family K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000004904 123.0
HKD3_k127_5229628_2 COG1960 Acyl-CoA dehydrogenases - - - 6.258e-219 683.0
HKD3_k127_5229628_3 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 599.0
HKD3_k127_5229628_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 502.0
HKD3_k127_5229628_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 511.0
HKD3_k127_5229628_6 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 434.0
HKD3_k127_5229628_7 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
HKD3_k127_5229628_8 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 399.0
HKD3_k127_5229628_9 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 298.0
HKD3_k127_5231360_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.76e-321 988.0
HKD3_k127_5231360_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 9.716e-318 975.0
HKD3_k127_5231360_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001691 242.0
HKD3_k127_5231360_11 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000006222 154.0
HKD3_k127_5231360_12 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000002627 111.0
HKD3_k127_5231360_13 Dodecin K09165 - - 0.00000000000000000000001163 103.0
HKD3_k127_5231360_2 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 7.934e-317 976.0
HKD3_k127_5231360_3 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 1.721e-295 915.0
HKD3_k127_5231360_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 7.332e-293 902.0
HKD3_k127_5231360_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 539.0
HKD3_k127_5231360_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 519.0
HKD3_k127_5231360_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 516.0
HKD3_k127_5231360_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 462.0
HKD3_k127_5231360_9 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 306.0
HKD3_k127_5253850_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.061e-292 900.0
HKD3_k127_5253850_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 428.0
HKD3_k127_5253850_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004896 141.0
HKD3_k127_5253850_3 membrane - - - 0.0000000000000000000000000000000337 129.0
HKD3_k127_5253850_4 - - - - 0.00000000000001546 79.0
HKD3_k127_5272789_0 P-aminobenzoate N-oxygenase AurF - - - 7.919e-222 690.0
HKD3_k127_5272789_1 P-aminobenzoate N-oxygenase AurF - - - 3.081e-211 659.0
HKD3_k127_5272789_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 326.0
HKD3_k127_5272789_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 238.0
HKD3_k127_5272789_14 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
HKD3_k127_5272789_15 - - - - 0.00000000000000000000000000000000000000000001555 162.0
HKD3_k127_5272789_16 YGGT family K02221 - - 0.0000000000000000000000000000000002082 133.0
HKD3_k127_5272789_17 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000007033 109.0
HKD3_k127_5272789_2 Receptor family ligand binding region - - - 1.132e-208 655.0
HKD3_k127_5272789_3 Oxidoreductase NAD-binding domain K21832 - - 3.023e-197 620.0
HKD3_k127_5272789_4 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 563.0
HKD3_k127_5272789_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 484.0
HKD3_k127_5272789_6 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 477.0
HKD3_k127_5272789_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 458.0
HKD3_k127_5272789_8 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 379.0
HKD3_k127_5272789_9 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 363.0
HKD3_k127_5275137_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 2104.0
HKD3_k127_5275137_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1833.0
HKD3_k127_5275137_10 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000001104 213.0
HKD3_k127_5275137_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000001917 171.0
HKD3_k127_5275137_12 - - - - 0.000000000000000000000000000000003685 130.0
HKD3_k127_5275137_13 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000002726 123.0
HKD3_k127_5275137_15 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.0000000000000000002699 93.0
HKD3_k127_5275137_16 - - - - 0.00000000000000005742 80.0
HKD3_k127_5275137_2 Belongs to the ClpA ClpB family K03694 - - 0.0 1450.0
HKD3_k127_5275137_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 2.092e-260 816.0
HKD3_k127_5275137_4 Peptidogalycan biosysnthesis/recognition K09919 - - 7.873e-244 754.0
HKD3_k127_5275137_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 572.0
HKD3_k127_5275137_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 399.0
HKD3_k127_5275137_7 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001419 283.0
HKD3_k127_5275137_8 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000007615 225.0
HKD3_k127_5275137_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000001857 218.0
HKD3_k127_5278122_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 374.0
HKD3_k127_5278122_1 - - - - 0.00000000000004151 75.0
HKD3_k127_5278122_2 TIGRFAM Dyp-type peroxidase family K07223 - - 0.0000000002758 63.0
HKD3_k127_5278156_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 556.0
HKD3_k127_5278156_1 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 489.0
HKD3_k127_5278156_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
HKD3_k127_5278156_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000003117 186.0
HKD3_k127_5297132_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 590.0
HKD3_k127_5297132_1 Ribosomal protein L11 methyltransferase (PrmA) K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 466.0
HKD3_k127_5297132_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 461.0
HKD3_k127_5297132_3 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000002184 164.0
HKD3_k127_5317176_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001523 234.0
HKD3_k127_5317176_1 transporter solute receptor, DctP family - - - 0.0000000000000000000000000000000003123 145.0
HKD3_k127_5317176_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000001689 62.0
HKD3_k127_5323560_0 Amidase - - - 1.09e-267 828.0
HKD3_k127_5323560_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 7.797e-248 778.0
HKD3_k127_5323560_10 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000000000000001893 227.0
HKD3_k127_5323560_11 CHAP domain - - - 0.0000000000000000000000000000000001344 150.0
HKD3_k127_5323560_12 electron transfer activity K08738 - - 0.00000000000000000002548 106.0
HKD3_k127_5323560_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.125e-199 623.0
HKD3_k127_5323560_3 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 595.0
HKD3_k127_5323560_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 486.0
HKD3_k127_5323560_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 475.0
HKD3_k127_5323560_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 440.0
HKD3_k127_5323560_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 452.0
HKD3_k127_5323560_8 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 421.0
HKD3_k127_5323560_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005557 282.0
HKD3_k127_5352891_0 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.0 1000.0
HKD3_k127_5352891_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 548.0
HKD3_k127_5352891_2 KR domain K13774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 491.0
HKD3_k127_5400711_0 Patatin-like phospholipase K07001 - - 0.0 1027.0
HKD3_k127_5400711_1 Amidase - - - 2.768e-247 767.0
HKD3_k127_5400711_10 transcriptional regulator, ArsR family - - - 0.0000000000000000001014 89.0
HKD3_k127_5400711_11 transcriptional regulator, ArsR family - - - 0.0000000000000001335 81.0
HKD3_k127_5400711_12 Protein of unknown function (DUF2000) - - - 0.000003265 58.0
HKD3_k127_5400711_13 Protein of unknown function (DUF2000) - - - 0.0008714 46.0
HKD3_k127_5400711_2 Protein of unknown function (DUF2817) - - - 8.479e-209 652.0
HKD3_k127_5400711_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 567.0
HKD3_k127_5400711_4 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 372.0
HKD3_k127_5400711_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 326.0
HKD3_k127_5400711_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 318.0
HKD3_k127_5400711_7 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000000000000002758 198.0
HKD3_k127_5400711_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000003096 197.0
HKD3_k127_5400711_9 Protein of unknown function (DUF2000) - - - 0.0000000000000000000000000000000002291 138.0
HKD3_k127_5408411_0 Major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 475.0
HKD3_k127_5408411_1 Biotin-lipoyl like K03543,K15549 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 420.0
HKD3_k127_5408411_2 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 374.0
HKD3_k127_5408411_3 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000004866 115.0
HKD3_k127_5412924_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 572.0
HKD3_k127_5412924_1 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 449.0
HKD3_k127_5412924_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 337.0
HKD3_k127_5412924_3 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
HKD3_k127_5437107_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 4.467e-314 967.0
HKD3_k127_5437107_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.951e-260 812.0
HKD3_k127_5437107_2 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 381.0
HKD3_k127_5437107_3 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 308.0
HKD3_k127_5437107_4 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 253.0
HKD3_k127_5438152_0 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
HKD3_k127_5438152_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 281.0
HKD3_k127_5438152_2 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 290.0
HKD3_k127_5438152_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000002973 97.0
HKD3_k127_5455156_0 Beta-lactamase - - - 1.274e-249 796.0
HKD3_k127_5455156_1 NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 598.0
HKD3_k127_5455156_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000005647 172.0
HKD3_k127_5455156_11 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000006547 153.0
HKD3_k127_5455156_13 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.000000000000005108 87.0
HKD3_k127_5455156_14 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.00000002586 57.0
HKD3_k127_5455156_15 Protein of unknown function (DUF465) K09794 - - 0.0000000611 65.0
HKD3_k127_5455156_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 567.0
HKD3_k127_5455156_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 545.0
HKD3_k127_5455156_4 FAD binding domain K00480,K14974 - 1.14.13.1,1.14.13.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 538.0
HKD3_k127_5455156_5 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 441.0
HKD3_k127_5455156_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 409.0
HKD3_k127_5455156_7 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 304.0
HKD3_k127_5455156_8 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009068 283.0
HKD3_k127_5455156_9 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005053 274.0
HKD3_k127_5456365_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.551e-227 716.0
HKD3_k127_5456365_1 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 470.0
HKD3_k127_5456365_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 443.0
HKD3_k127_5456365_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001377 279.0
HKD3_k127_5456365_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000003317 284.0
HKD3_k127_5456365_5 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
HKD3_k127_5456365_6 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.000000000000000000000000000000000000000000000000000005863 190.0
HKD3_k127_5456365_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000004392 191.0
HKD3_k127_5456365_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000001667 99.0
HKD3_k127_5456365_9 SnoaL-like polyketide cyclase - - - 0.0003006 46.0
HKD3_k127_5518415_0 Sulfatase - - - 1.649e-291 899.0
HKD3_k127_5518415_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 577.0
HKD3_k127_5538320_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0 1071.0
HKD3_k127_5538320_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 1.546e-251 784.0
HKD3_k127_5546736_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 4.928e-203 633.0
HKD3_k127_5546736_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 522.0
HKD3_k127_5546736_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 419.0
HKD3_k127_5546736_3 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 396.0
HKD3_k127_5546736_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 356.0
HKD3_k127_5546736_5 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001978 266.0
HKD3_k127_5565950_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.46e-322 989.0
HKD3_k127_5565950_1 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 395.0
HKD3_k127_5565950_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006772 234.0
HKD3_k127_5565950_3 - - - - 0.000000000000000000000000000000000000000000000008818 195.0
HKD3_k127_5565950_4 Protein of unknown function (DUF805) - - - 0.00000000000000007069 87.0
HKD3_k127_5615188_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.317e-308 952.0
HKD3_k127_5615188_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 548.0
HKD3_k127_5615188_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 423.0
HKD3_k127_5615188_3 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 361.0
HKD3_k127_5615188_4 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
HKD3_k127_5615188_5 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000008237 170.0
HKD3_k127_5637246_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 295.0
HKD3_k127_5637246_1 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000001808 237.0
HKD3_k127_5637246_2 Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate K09018 - 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000002071 211.0
HKD3_k127_5637246_3 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 - - 0.00000000000000000000000000000000000000000000000000000000002644 222.0
HKD3_k127_5637246_4 transport system permease component - - - 0.00000000000000000000000000000000000000000000003183 188.0
HKD3_k127_5652768_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 519.0
HKD3_k127_5652768_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 412.0
HKD3_k127_5652768_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005767 265.0
HKD3_k127_5652768_3 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
HKD3_k127_5652768_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001345 256.0
HKD3_k127_5652768_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000002652 200.0
HKD3_k127_5652768_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000004492 119.0
HKD3_k127_5652768_7 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001665 130.0
HKD3_k127_5652768_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000579 68.0
HKD3_k127_5656918_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.322e-274 848.0
HKD3_k127_5656918_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 9.015e-206 643.0
HKD3_k127_5656918_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 475.0
HKD3_k127_5656918_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD3_k127_5656918_4 carbohydrate metabolic process K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 412.0
HKD3_k127_5656918_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001504 270.0
HKD3_k127_5656918_6 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001504 252.0
HKD3_k127_5656918_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD3_k127_5666835_0 oxidoreductase FAD NAD(P)-binding domain protein K14581 - 1.18.1.7 6.156e-201 640.0
HKD3_k127_5666835_1 ATPase (AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 537.0
HKD3_k127_5666835_2 Pfam:Pyridox_oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 352.0
HKD3_k127_5666835_3 Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 336.0
HKD3_k127_5666835_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 311.0
HKD3_k127_5666835_5 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000000001369 214.0
HKD3_k127_5666835_6 Transcriptional regulator, MarR family - - - 0.0000000000000000000000000000000000000000000000000000001427 214.0
HKD3_k127_5666835_7 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000007664 148.0
HKD3_k127_5684304_0 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 407.0
HKD3_k127_5684304_1 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 378.0
HKD3_k127_5684304_2 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
HKD3_k127_5684304_4 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
HKD3_k127_5684304_5 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000003026 212.0
HKD3_k127_5684304_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000004406 132.0
HKD3_k127_5684304_7 Redoxin - - - 0.0000000000002003 73.0
HKD3_k127_5684409_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 0.0 1677.0
HKD3_k127_5684409_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 5.475e-203 641.0
HKD3_k127_5684409_10 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.0000000000000000000000000000000000000005865 149.0
HKD3_k127_5684409_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000006708 126.0
HKD3_k127_5684409_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 1.975e-195 611.0
HKD3_k127_5684409_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 1.411e-194 610.0
HKD3_k127_5684409_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 584.0
HKD3_k127_5684409_5 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 481.0
HKD3_k127_5684409_6 ATPases associated with a variety of cellular activities K02074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 447.0
HKD3_k127_5684409_7 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 370.0
HKD3_k127_5684409_8 transcriptional regulator K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 328.0
HKD3_k127_5684409_9 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000005614 217.0
HKD3_k127_5695639_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13926 - - 0.0 1304.0
HKD3_k127_5695639_1 Aconitase family (aconitate hydratase) - - - 1.11e-264 819.0
HKD3_k127_5695639_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000123 158.0
HKD3_k127_5695639_11 Domain of unknown function (DUF1127) - - - 0.0000000000000000000007188 99.0
HKD3_k127_5695639_12 Domain of unknown function (DUF1127) - - - 0.00000008698 55.0
HKD3_k127_5695639_2 Luciferase-like monooxygenase - - - 3.469e-220 685.0
HKD3_k127_5695639_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 557.0
HKD3_k127_5695639_4 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 564.0
HKD3_k127_5695639_5 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 452.0
HKD3_k127_5695639_6 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 453.0
HKD3_k127_5695639_7 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 453.0
HKD3_k127_5695639_8 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 392.0
HKD3_k127_5695639_9 Aconitase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 366.0
HKD3_k127_5718487_0 FAD dependent oxidoreductase - - - 8.318e-249 772.0
HKD3_k127_5718487_1 Patatin-like phospholipase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008841 279.0
HKD3_k127_5718487_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000001813 237.0
HKD3_k127_5731697_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 3.105e-234 730.0
HKD3_k127_5731697_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 3.3e-201 638.0
HKD3_k127_5731697_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.000000000000000000000000000000000000000001082 161.0
HKD3_k127_5731697_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000001187 117.0
HKD3_k127_5746863_0 5-oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 5e-324 1034.0
HKD3_k127_5746863_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 1.034e-238 739.0
HKD3_k127_5746863_2 Aminotransferase class-V - - - 9.574e-223 693.0
HKD3_k127_5746863_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 1.487e-195 613.0
HKD3_k127_5746863_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 586.0
HKD3_k127_5746863_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 540.0
HKD3_k127_5746863_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000001411 124.0
HKD3_k127_5751842_0 L,D-transpeptidase catalytic domain K21470 - - 5.702e-246 766.0
HKD3_k127_5751842_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 6.383e-225 698.0
HKD3_k127_5751842_2 FAD binding domain - - - 1.334e-203 647.0
HKD3_k127_5791298_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003544 274.0
HKD3_k127_5791298_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000003576 77.0
HKD3_k127_5805344_0 Amidohydrolase - - - 8.482e-207 647.0
HKD3_k127_5805344_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 582.0
HKD3_k127_5805344_10 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
HKD3_k127_5805344_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 571.0
HKD3_k127_5805344_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 438.0
HKD3_k127_5805344_4 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 357.0
HKD3_k127_5805344_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009786 261.0
HKD3_k127_5805344_6 protein containing double-stranded beta helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000228 240.0
HKD3_k127_5805344_7 Sel1-like repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
HKD3_k127_5805344_8 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000001704 240.0
HKD3_k127_5805344_9 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000001846 216.0
HKD3_k127_5825942_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 8.513e-297 919.0
HKD3_k127_5825942_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 572.0
HKD3_k127_5825942_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 576.0
HKD3_k127_5825942_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 530.0
HKD3_k127_5825942_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 524.0
HKD3_k127_5825942_5 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 452.0
HKD3_k127_5825942_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 387.0
HKD3_k127_5835567_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 4.488e-215 670.0
HKD3_k127_5835567_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 594.0
HKD3_k127_5835567_2 Methionine synthase K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 569.0
HKD3_k127_5835567_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 335.0
HKD3_k127_5835567_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000003522 213.0
HKD3_k127_5841234_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.354e-207 665.0
HKD3_k127_5841234_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 419.0
HKD3_k127_5841234_2 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 412.0
HKD3_k127_5841234_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 366.0
HKD3_k127_5841234_4 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 315.0
HKD3_k127_5841234_5 Nitrilotriacetate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005807 236.0
HKD3_k127_5841494_0 phosphomannomutase K01840 - 5.4.2.8 1.179e-276 854.0
HKD3_k127_5841494_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 6.322e-255 789.0
HKD3_k127_5841494_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 551.0
HKD3_k127_5841494_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 516.0
HKD3_k127_5841494_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 499.0
HKD3_k127_5841494_5 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 350.0
HKD3_k127_5841494_6 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
HKD3_k127_584571_0 Luciferase-like monooxygenase - - - 9.152e-217 702.0
HKD3_k127_584571_1 COG0477 Permeases of the major facilitator superfamily - - - 9.117e-216 673.0
HKD3_k127_584571_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 414.0
HKD3_k127_584571_3 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 308.0
HKD3_k127_584571_4 DDE superfamily endonuclease K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000764 262.0
HKD3_k127_584571_5 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001674 245.0
HKD3_k127_584571_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000001684 250.0
HKD3_k127_584571_7 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000001516 220.0
HKD3_k127_584571_8 'Paired box' domain K07499 - - 0.00000000000000000000955 96.0
HKD3_k127_586423_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1421.0
HKD3_k127_586423_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 600.0
HKD3_k127_586423_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 557.0
HKD3_k127_586423_3 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 541.0
HKD3_k127_586423_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000001865 186.0
HKD3_k127_586423_5 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000001024 80.0
HKD3_k127_5887207_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1832.0
HKD3_k127_5887207_1 Coenzyme A transferase K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 422.0
HKD3_k127_5887207_2 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 395.0
HKD3_k127_5887207_3 PFAM ABC transporter K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 392.0
HKD3_k127_5887207_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
HKD3_k127_5887207_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 362.0
HKD3_k127_5887207_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 371.0
HKD3_k127_5887207_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001145 275.0
HKD3_k127_5887207_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000008399 164.0
HKD3_k127_5887207_9 DNA replication initiation - - - 0.000000000000000000000000335 120.0
HKD3_k127_5953310_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 604.0
HKD3_k127_5953310_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 449.0
HKD3_k127_5969600_0 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 9.027e-261 810.0
HKD3_k127_5969600_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 406.0
HKD3_k127_5969600_2 Acyltransferase family - - - 0.000000000000000000000000000000000008847 151.0
HKD3_k127_5969600_3 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000003264 117.0
HKD3_k127_5969600_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00003188 47.0
HKD3_k127_5986315_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 7.043e-266 822.0
HKD3_k127_5986315_1 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 1.191e-218 684.0
HKD3_k127_5986315_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 370.0
HKD3_k127_5986315_3 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 297.0
HKD3_k127_5986315_4 DNA polymerase K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000003048 231.0
HKD3_k127_5994644_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1118.0
HKD3_k127_5994644_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 465.0
HKD3_k127_5994644_2 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 353.0
HKD3_k127_5994644_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
HKD3_k127_5994644_4 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 301.0
HKD3_k127_6018581_0 Proton-conducting membrane transporter - - - 5.376e-300 933.0
HKD3_k127_6018581_1 Proton-conducting membrane transporter K12141 - - 2.426e-246 767.0
HKD3_k127_6018581_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 449.0
HKD3_k127_6018581_3 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 327.0
HKD3_k127_6018581_4 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
HKD3_k127_6018581_5 Integral membrane protein TerC family - - - 0.000000002194 59.0
HKD3_k127_6018581_6 NADH-ubiquinone oxidoreductase chain 49kDa - - - 0.000000007407 57.0
HKD3_k127_6043753_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 566.0
HKD3_k127_6043753_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000046 249.0
HKD3_k127_6043753_2 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004101 269.0
HKD3_k127_6049985_0 Belongs to the amidase family - - - 5.21e-262 811.0
HKD3_k127_6049985_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000001102 102.0
HKD3_k127_6049985_3 Phospholipase D. Active site motifs. - - - 0.00003299 53.0
HKD3_k127_6082499_0 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 512.0
HKD3_k127_6082499_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 467.0
HKD3_k127_6082499_2 Protein of unknown function (DUF2848) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 327.0
HKD3_k127_6082499_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000004385 220.0
HKD3_k127_6114972_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.62e-321 987.0
HKD3_k127_6141240_0 Acetyl-coenzyme A transporter 1 K08218 - - 1.197e-203 647.0
HKD3_k127_6141240_1 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 569.0
HKD3_k127_6141240_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 459.0
HKD3_k127_6141240_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 403.0
HKD3_k127_6141240_4 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000002308 222.0
HKD3_k127_6141240_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000001524 93.0
HKD3_k127_6204042_0 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 456.0
HKD3_k127_6204042_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000123 196.0
HKD3_k127_6204042_2 Major Facilitator Superfamily K03446 - - 0.0000000000000000000000000000000002847 137.0
HKD3_k127_621669_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0 1132.0
HKD3_k127_621669_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 1.252e-210 658.0
HKD3_k127_621669_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000004863 104.0
HKD3_k127_6222240_0 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 504.0
HKD3_k127_6222240_1 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00467,K16422 - 1.1.2.3,1.1.3.46,1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 419.0
HKD3_k127_6222240_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 393.0
HKD3_k127_6222240_3 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
HKD3_k127_6222240_4 Protein of unknown function (DUF3574) - - - 0.00000000000000000000000000000000000000000000005556 177.0
HKD3_k127_6222240_5 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.00000000000000000002118 93.0
HKD3_k127_6226171_0 acid transport system permease K09970 - - 1.277e-223 696.0
HKD3_k127_6226171_1 general L-amino acid-binding periplasmic protein AapJ K09969 - - 7.294e-200 627.0
HKD3_k127_6226171_2 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 596.0
HKD3_k127_6226171_3 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 578.0
HKD3_k127_6226171_4 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 566.0
HKD3_k127_6226171_5 acid transport K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 480.0
HKD3_k127_6226171_6 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 388.0
HKD3_k127_6226171_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 - 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 342.0
HKD3_k127_6226171_8 Lipase (class 2) K01046 - 3.1.1.3 0.0007936 44.0
HKD3_k127_6233818_0 Peptidase family M20/M25/M40 - - - 3.317e-299 919.0
HKD3_k127_6233818_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.411e-274 853.0
HKD3_k127_6233818_10 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000005008 146.0
HKD3_k127_6233818_11 ChrR Cupin-like domain K07167 - - 0.00000000000000000000000000000003688 136.0
HKD3_k127_6233818_12 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000003091 117.0
HKD3_k127_6233818_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.653e-239 744.0
HKD3_k127_6233818_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 9.505e-207 651.0
HKD3_k127_6233818_4 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 479.0
HKD3_k127_6233818_5 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
HKD3_k127_6233818_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 334.0
HKD3_k127_6233818_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 315.0
HKD3_k127_6233818_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001924 170.0
HKD3_k127_6233818_9 GYD domain - - - 0.0000000000000000000000000000000000000000008471 162.0
HKD3_k127_6234168_0 Carboxyl transferase domain - - - 7.759e-312 959.0
HKD3_k127_6234168_1 Ring hydroxylating alpha subunit (catalytic domain) K03268,K05708 - 1.14.12.11,1.14.12.19,1.14.12.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 533.0
HKD3_k127_6234168_2 Cell division protein ZipA - - - 0.00000000000000000000000000000000000000000000000000000000000001816 220.0
HKD3_k127_6234168_3 Ring hydroxylating beta subunit K15750 - 1.14.12.18 0.00000000000000000000000000000000000000000000000000000000258 208.0
HKD3_k127_6234168_4 PFAM DoxX K15977 - - 0.000000000000000000005878 108.0
HKD3_k127_6234168_5 - - - - 0.000007113 58.0
HKD3_k127_6239569_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.724e-296 911.0
HKD3_k127_6239569_1 Uncharacterized protein conserved in bacteria (DUF2272) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 372.0
HKD3_k127_6239569_2 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001933 252.0
HKD3_k127_6239569_3 Major Facilitator Superfamily - - - 0.000000000000004661 81.0
HKD3_k127_6239569_4 acetyltransferase - - - 0.000103 53.0
HKD3_k127_6240094_0 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 4.426e-224 696.0
HKD3_k127_6240094_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.529e-206 642.0
HKD3_k127_6240094_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
HKD3_k127_6241753_0 ABC transporter K02471 - - 4.376e-268 835.0
HKD3_k127_6241753_1 Amidohydrolase family - - - 1.081e-265 826.0
HKD3_k127_6241753_10 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 498.0
HKD3_k127_6241753_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 448.0
HKD3_k127_6241753_12 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 430.0
HKD3_k127_6241753_13 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 419.0
HKD3_k127_6241753_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 400.0
HKD3_k127_6241753_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 398.0
HKD3_k127_6241753_16 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008136 261.0
HKD3_k127_6241753_17 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
HKD3_k127_6241753_18 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000203 202.0
HKD3_k127_6241753_19 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000001367 207.0
HKD3_k127_6241753_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 4.693e-219 682.0
HKD3_k127_6241753_20 FAD linked oxidases, C-terminal domain K18930 - - 0.000000000000000000000000000000000000000000000001821 174.0
HKD3_k127_6241753_21 - - - - 0.000000000000000001638 92.0
HKD3_k127_6241753_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.403e-216 685.0
HKD3_k127_6241753_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.198e-215 677.0
HKD3_k127_6241753_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 6.138e-209 676.0
HKD3_k127_6241753_6 Fusaric acid resistance protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 563.0
HKD3_k127_6241753_7 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 534.0
HKD3_k127_6241753_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 545.0
HKD3_k127_6241753_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 492.0
HKD3_k127_6257994_0 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 5.603e-258 797.0
HKD3_k127_6257994_1 Histidine kinase - - - 6.778e-224 703.0
HKD3_k127_6257994_2 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 565.0
HKD3_k127_6257994_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000354 178.0
HKD3_k127_6257994_4 Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000003942 154.0
HKD3_k127_6259938_0 NAD synthase K01950 - 6.3.5.1 0.0 1180.0
HKD3_k127_6259938_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 9.076e-286 882.0
HKD3_k127_6259938_10 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
HKD3_k127_6259938_11 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000001152 225.0
HKD3_k127_6259938_12 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000002448 155.0
HKD3_k127_6259938_13 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0004293 44.0
HKD3_k127_6259938_2 AMP-binding enzyme C-terminal domain - - - 5.947e-283 875.0
HKD3_k127_6259938_3 III protein, CoA-transferase family - - - 1.037e-231 719.0
HKD3_k127_6259938_4 hydroxy-methylglutaryl-CoA lyase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 577.0
HKD3_k127_6259938_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 537.0
HKD3_k127_6259938_6 Amidohydrolase family K01461 - 3.5.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 515.0
HKD3_k127_6259938_7 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 456.0
HKD3_k127_6259938_8 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 297.0
HKD3_k127_6259938_9 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009775 256.0
HKD3_k127_6267024_0 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 585.0
HKD3_k127_6267024_1 Catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 584.0
HKD3_k127_6267024_2 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006223 278.0
HKD3_k127_6267024_3 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001996 274.0
HKD3_k127_6267024_4 cobalamin synthesis CobW domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007448 264.0
HKD3_k127_6267024_5 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000001193 134.0
HKD3_k127_6267024_6 RDD family - - - 0.000004929 52.0
HKD3_k127_6285024_0 Hydantoinase B/oxoprolinase - - - 0.0 1016.0
HKD3_k127_6285024_1 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1010.0
HKD3_k127_6285024_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
HKD3_k127_6285024_11 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
HKD3_k127_6285024_12 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000000000000000000000000000000001358 155.0
HKD3_k127_6285024_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000009893 78.0
HKD3_k127_6285024_2 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 8.678e-267 826.0
HKD3_k127_6285024_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 2.281e-198 631.0
HKD3_k127_6285024_4 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 462.0
HKD3_k127_6285024_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 457.0
HKD3_k127_6285024_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 416.0
HKD3_k127_6285024_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 350.0
HKD3_k127_6285024_8 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 313.0
HKD3_k127_6285024_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
HKD3_k127_6289450_0 COG0457 FOG TPR repeat - - - 1.055e-290 899.0
HKD3_k127_6289450_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 415.0
HKD3_k127_6289450_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 396.0
HKD3_k127_6289450_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 351.0
HKD3_k127_6289450_4 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000007236 227.0
HKD3_k127_6289450_5 - - - - 0.00000000000000000000000000000000000000000000114 180.0
HKD3_k127_6306130_0 Class II Aldolase and Adducin N-terminal domain - - - 3.761e-297 916.0
HKD3_k127_6306130_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 580.0
HKD3_k127_6306130_2 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.0000000000000003292 78.0
HKD3_k127_6311322_0 Psort location Cytoplasmic, score 7.50 - - - 1.113e-255 790.0
HKD3_k127_6311322_1 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 1.018e-197 620.0
HKD3_k127_6311322_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.944e-196 615.0
HKD3_k127_6311322_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 549.0
HKD3_k127_6311322_4 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 534.0
HKD3_k127_6311322_5 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 527.0
HKD3_k127_6311322_6 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 475.0
HKD3_k127_6311322_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 453.0
HKD3_k127_6311322_8 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 420.0
HKD3_k127_6318245_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 451.0
HKD3_k127_6318245_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 431.0
HKD3_k127_6318245_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 363.0
HKD3_k127_6318245_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001322 273.0
HKD3_k127_6318245_4 flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group K06205 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000001784 258.0
HKD3_k127_632257_0 Alpha-2-Macroglobulin K06894 - - 0.0 2187.0
HKD3_k127_632257_1 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000000000000000000000000000001656 221.0
HKD3_k127_6323628_0 - K13582,K13924,K15580 - 2.1.1.80,3.1.1.61 0.0 1454.0
HKD3_k127_6323628_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 600.0
HKD3_k127_6323628_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 572.0
HKD3_k127_6323628_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 550.0
HKD3_k127_6323628_4 mitochondrial gene expression - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 536.0
HKD3_k127_6323628_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 489.0
HKD3_k127_6323628_6 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 317.0
HKD3_k127_6323628_7 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 301.0
HKD3_k127_6340949_0 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 7.393e-214 673.0
HKD3_k127_6340949_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 512.0
HKD3_k127_6340949_2 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 490.0
HKD3_k127_6340949_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 264.0
HKD3_k127_6340949_4 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000001619 217.0
HKD3_k127_6340949_5 - - - - 0.0000000000000000000000000000000000000000000000000001533 199.0
HKD3_k127_6340949_6 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000003541 125.0
HKD3_k127_6340949_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000002947 84.0
HKD3_k127_6352577_0 Conserved region in glutamate synthase - - - 1.414e-291 908.0
HKD3_k127_6352577_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 5.711e-243 754.0
HKD3_k127_6352577_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 303.0
HKD3_k127_6352577_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
HKD3_k127_6352577_13 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000002079 169.0
HKD3_k127_6352577_14 PFAM Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000003835 136.0
HKD3_k127_6352577_2 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 547.0
HKD3_k127_6352577_3 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 514.0
HKD3_k127_6352577_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 469.0
HKD3_k127_6352577_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 412.0
HKD3_k127_6352577_6 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 388.0
HKD3_k127_6352577_7 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 392.0
HKD3_k127_6352577_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 350.0
HKD3_k127_6352577_9 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
HKD3_k127_6388222_0 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain - - - 2.578e-245 758.0
HKD3_k127_6388222_1 BFD-like [2Fe-2S] binding domain - - - 8.61e-242 754.0
HKD3_k127_6388222_10 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001141 183.0
HKD3_k127_6388222_11 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000002374 157.0
HKD3_k127_6388222_12 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000002291 139.0
HKD3_k127_6388222_13 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000000001255 132.0
HKD3_k127_6388222_14 - - - - 0.00000000000000000000000000009454 117.0
HKD3_k127_6388222_15 - - - - 0.0000000000000000000000164 111.0
HKD3_k127_6388222_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.371e-232 722.0
HKD3_k127_6388222_3 FAD dependent oxidoreductase - - - 3.932e-219 682.0
HKD3_k127_6388222_4 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 531.0
HKD3_k127_6388222_5 Methyltransferase K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 501.0
HKD3_k127_6388222_6 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 297.0
HKD3_k127_6388222_7 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 298.0
HKD3_k127_6388222_8 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003874 271.0
HKD3_k127_6388222_9 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000003582 202.0
HKD3_k127_64016_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 9.634e-234 725.0
HKD3_k127_64016_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 550.0
HKD3_k127_64016_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 529.0
HKD3_k127_64016_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 527.0
HKD3_k127_64016_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 507.0
HKD3_k127_64016_5 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
HKD3_k127_64016_6 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 293.0
HKD3_k127_64016_7 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
HKD3_k127_64016_8 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000001277 171.0
HKD3_k127_64016_9 Protein of unknown function (DUF1254) - - - 0.000000000000000009392 83.0
HKD3_k127_6428785_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.285e-298 920.0
HKD3_k127_6428785_1 DNA polymerase III subunit delta K02341 - 2.7.7.7 6.432e-207 647.0
HKD3_k127_6428785_11 Resolvase, N terminal domain - - - 0.000000000003366 69.0
HKD3_k127_6428785_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 3.69e-200 631.0
HKD3_k127_6428785_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 480.0
HKD3_k127_6428785_4 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 440.0
HKD3_k127_6428785_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 328.0
HKD3_k127_6428785_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007556 277.0
HKD3_k127_6428785_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
HKD3_k127_6428785_8 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000002014 148.0
HKD3_k127_6428785_9 Cell division protein K03591,K03749 - - 0.000000000000000000000000000003527 132.0
HKD3_k127_644833_0 PFAM peptidase S15 K06978 - - 1.543e-241 762.0
HKD3_k127_644833_1 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 435.0
HKD3_k127_644833_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
HKD3_k127_644833_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 372.0
HKD3_k127_644833_4 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 291.0
HKD3_k127_644833_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000001072 134.0
HKD3_k127_644833_7 GDSL-like Lipase/Acylhydrolase family - - - 0.0001846 53.0
HKD3_k127_6465185_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0 1041.0
HKD3_k127_6465185_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 487.0
HKD3_k127_6465185_2 ATPases associated with a variety of cellular activities K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 331.0
HKD3_k127_6465185_3 ABC transporter K11962 - - 0.00000000000000000001407 91.0
HKD3_k127_6465326_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 567.0
HKD3_k127_6465326_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 507.0
HKD3_k127_6465326_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 473.0
HKD3_k127_6465326_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 460.0
HKD3_k127_6465326_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000003473 93.0
HKD3_k127_6465326_5 mRNA binding K07339 - - 0.00000000002432 68.0
HKD3_k127_6465326_6 Protein of unknown function (DUF4239) - - - 0.000000002566 59.0
HKD3_k127_6473892_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.03e-322 990.0
HKD3_k127_6473892_1 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 1.009e-309 958.0
HKD3_k127_6473892_13 - - - - 0.00001124 59.0
HKD3_k127_6473892_14 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.00002436 52.0
HKD3_k127_6473892_2 Adenylate cyclase - - - 1.877e-308 954.0
HKD3_k127_6473892_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.066e-250 789.0
HKD3_k127_6473892_4 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 539.0
HKD3_k127_6473892_5 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 458.0
HKD3_k127_6473892_6 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 389.0
HKD3_k127_6473892_7 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 341.0
HKD3_k127_6473892_8 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000003075 248.0
HKD3_k127_6473892_9 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.0000000000000000000000000000000000000000000000000000003744 202.0
HKD3_k127_6488143_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 385.0
HKD3_k127_6488143_1 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 357.0
HKD3_k127_6488143_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 329.0
HKD3_k127_6488143_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K02228 - 2.1.1.152 0.00000000000000000000000000000000000000000000000000006568 189.0
HKD3_k127_6488143_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000001731 182.0
HKD3_k127_6488143_5 GYD domain - - - 0.000000000000000000000000000000009087 129.0
HKD3_k127_6488143_6 - - - - 0.0000000000000000000000000009649 130.0
HKD3_k127_6488143_7 Cupin domain - - - 0.00000005233 59.0
HKD3_k127_6496247_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1032.0
HKD3_k127_6496247_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 504.0
HKD3_k127_6496247_2 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 329.0
HKD3_k127_6496247_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000006007 272.0
HKD3_k127_6496247_4 NosL K19342 - - 0.0000000000000000000000000000000000000000000000000000002736 211.0
HKD3_k127_6496247_5 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000000005692 171.0
HKD3_k127_6496247_7 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000002153 120.0
HKD3_k127_6496247_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000001493 70.0
HKD3_k127_6496247_9 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 0.000002395 51.0
HKD3_k127_652446_0 cobalamin synthesis protein - - - 2.045e-226 704.0
HKD3_k127_652446_1 Aconitase family (aconitate hydratase) - - - 8.933e-220 691.0
HKD3_k127_652446_10 Flavin reductase like domain K09024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 312.0
HKD3_k127_652446_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000001611 240.0
HKD3_k127_652446_12 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000001327 240.0
HKD3_k127_652446_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000001396 126.0
HKD3_k127_652446_14 - - - - 0.000001426 51.0
HKD3_k127_652446_2 Resolvase K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 537.0
HKD3_k127_652446_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 437.0
HKD3_k127_652446_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 426.0
HKD3_k127_652446_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 413.0
HKD3_k127_652446_6 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 396.0
HKD3_k127_652446_7 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 383.0
HKD3_k127_652446_8 Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 376.0
HKD3_k127_652446_9 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 349.0
HKD3_k127_6529078_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 9.801e-200 625.0
HKD3_k127_6529078_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 512.0
HKD3_k127_6529078_2 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 333.0
HKD3_k127_6529078_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000001339 173.0
HKD3_k127_6536367_0 - - - - 0.0 1088.0
HKD3_k127_6536367_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5.4e-287 887.0
HKD3_k127_6536367_2 Sugar (and other) transporter - - - 1.402e-233 726.0
HKD3_k127_6536367_3 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 6.836e-218 680.0
HKD3_k127_6536367_4 Ketopantoate reductase PanE/ApbA C terminal - - - 1.039e-207 648.0
HKD3_k127_6536367_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 443.0
HKD3_k127_6536367_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002691 274.0
HKD3_k127_6536367_7 - - - - 0.000000000000000000000000000000000002261 149.0
HKD3_k127_6536367_8 - - - - 0.000000000000000000001252 111.0
HKD3_k127_6536367_9 - - - - 0.000000000002549 72.0
HKD3_k127_6554603_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1135.0
HKD3_k127_6561294_0 Bacterial extracellular solute-binding protein - - - 2.066e-235 736.0
HKD3_k127_6561294_1 Aminotransferase class I and II - - - 1.33e-230 719.0
HKD3_k127_6561294_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 374.0
HKD3_k127_6561294_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 330.0
HKD3_k127_6561294_12 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 289.0
HKD3_k127_6561294_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 8.777e-227 711.0
HKD3_k127_6561294_3 COG3839 ABC-type sugar transport systems, ATPase components - - - 2.271e-220 685.0
HKD3_k127_6561294_4 Malate/L-lactate dehydrogenase - - - 3.712e-214 667.0
HKD3_k127_6561294_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.087e-214 666.0
HKD3_k127_6561294_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 554.0
HKD3_k127_6561294_7 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 548.0
HKD3_k127_6561294_8 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 424.0
HKD3_k127_6561294_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 402.0
HKD3_k127_6571633_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1302.0
HKD3_k127_6581672_0 Binding-protein-dependent transport system inner membrane component K02011 - - 1.288e-261 817.0
HKD3_k127_6581672_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 548.0
HKD3_k127_6581672_10 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000001662 156.0
HKD3_k127_6581672_2 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 543.0
HKD3_k127_6581672_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 486.0
HKD3_k127_6581672_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 477.0
HKD3_k127_6581672_5 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 427.0
HKD3_k127_6581672_6 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 344.0
HKD3_k127_6581672_7 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 341.0
HKD3_k127_6581672_8 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 309.0
HKD3_k127_6581672_9 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000505 237.0
HKD3_k127_659662_0 Molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 534.0
HKD3_k127_659662_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 489.0
HKD3_k127_659662_2 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
HKD3_k127_659662_3 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000000000000000000000000000000000000000001399 220.0
HKD3_k127_659662_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.00000000000000000000000000000000000000118 163.0
HKD3_k127_6603130_0 Belongs to the DegT DnrJ EryC1 family - - - 2.416e-202 635.0
HKD3_k127_6603130_1 2-nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 601.0
HKD3_k127_6603130_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 318.0
HKD3_k127_6603130_11 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
HKD3_k127_6603130_12 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000002934 216.0
HKD3_k127_6603130_13 WxcM-like, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000001372 215.0
HKD3_k127_6603130_14 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000715 186.0
HKD3_k127_6603130_16 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000001549 110.0
HKD3_k127_6603130_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 567.0
HKD3_k127_6603130_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 501.0
HKD3_k127_6603130_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 492.0
HKD3_k127_6603130_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 481.0
HKD3_k127_6603130_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 468.0
HKD3_k127_6603130_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 - 4.2.1.46,4.2.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 413.0
HKD3_k127_6603130_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 403.0
HKD3_k127_6603130_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 372.0
HKD3_k127_6610196_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.729e-274 847.0
HKD3_k127_6610196_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000009737 135.0
HKD3_k127_6623602_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 570.0
HKD3_k127_6623602_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 349.0
HKD3_k127_6623602_2 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 286.0
HKD3_k127_6623602_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
HKD3_k127_6623602_4 - - - - 0.00000000000000000000000000000000000000000000000000000004192 198.0
HKD3_k127_6624290_0 beta-lactamase K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 600.0
HKD3_k127_6624290_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 404.0
HKD3_k127_6624290_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 361.0
HKD3_k127_6624290_3 Belongs to the pirin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 340.0
HKD3_k127_6624290_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000000000000000000004433 171.0
HKD3_k127_6624290_5 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000002403 121.0
HKD3_k127_6624290_6 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000006286 102.0
HKD3_k127_6624290_7 - - - - 0.000000000000001101 82.0
HKD3_k127_6627462_0 Domain of unknown function (DUF4175) - - - 0.0 1438.0
HKD3_k127_6627462_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1372.0
HKD3_k127_6627462_10 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003108 239.0
HKD3_k127_6627462_11 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001174 214.0
HKD3_k127_6627462_12 - - - - 0.00000000000000000000000000000000000000000000000000004069 192.0
HKD3_k127_6627462_13 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000009677 188.0
HKD3_k127_6627462_2 argininosuccinate lyase K01755 - 4.3.2.1 2.74e-269 833.0
HKD3_k127_6627462_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 6.031e-230 745.0
HKD3_k127_6627462_4 Belongs to the peptidase S1C family - - - 1.678e-226 708.0
HKD3_k127_6627462_5 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 387.0
HKD3_k127_6627462_6 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 373.0
HKD3_k127_6627462_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 307.0
HKD3_k127_6627462_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
HKD3_k127_6627462_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004399 262.0
HKD3_k127_6634321_0 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 0.0 1113.0
HKD3_k127_6634321_1 2-hydroxyacyl-CoA lyase 1 K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 518.0
HKD3_k127_6634321_10 Glyoxalase-like domain - - - 0.00000000000000000002029 92.0
HKD3_k127_6634321_11 Belongs to the ompA family - - - 0.000000000007478 72.0
HKD3_k127_6634321_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 472.0
HKD3_k127_6634321_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 464.0
HKD3_k127_6634321_4 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 448.0
HKD3_k127_6634321_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 383.0
HKD3_k127_6634321_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 333.0
HKD3_k127_6634321_7 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004526 279.0
HKD3_k127_6634321_8 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003609 240.0
HKD3_k127_6634321_9 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.0000000000000000000000000000255 122.0
HKD3_k127_6646862_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.678e-290 895.0
HKD3_k127_6647373_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 6.851e-251 781.0
HKD3_k127_6647373_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 491.0
HKD3_k127_6647859_0 glutamine synthetase K01915 - 6.3.1.2 1.74e-274 869.0
HKD3_k127_6647859_1 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 2.054e-267 827.0
HKD3_k127_6647859_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000143 147.0
HKD3_k127_6647859_11 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000001153 62.0
HKD3_k127_6647859_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 604.0
HKD3_k127_6647859_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 587.0
HKD3_k127_6647859_4 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 531.0
HKD3_k127_6647859_5 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 512.0
HKD3_k127_6647859_6 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 332.0
HKD3_k127_6647859_7 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
HKD3_k127_6647859_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000006547 153.0
HKD3_k127_6647859_9 Belongs to the amidase family - - - 0.00000000000000000000000000000000001415 146.0
HKD3_k127_6667734_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1294.0
HKD3_k127_6667734_1 monooxygenase K09018 - 1.14.99.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 557.0
HKD3_k127_6667734_2 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 382.0
HKD3_k127_6667734_3 ABC-type dipeptide transport system periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 412.0
HKD3_k127_6667734_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 320.0
HKD3_k127_6667734_5 N-terminal TM domain of oligopeptide transport permease C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 318.0
HKD3_k127_6667734_6 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 296.0
HKD3_k127_6667734_7 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 300.0
HKD3_k127_6692599_0 AlkA N-terminal domain K13529 - 3.2.2.21 8.731e-197 616.0
HKD3_k127_6692599_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 550.0
HKD3_k127_6692599_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
HKD3_k127_6692599_3 Inosine-uridine preferring nucleoside hydrolase K12700 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
HKD3_k127_6692599_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006883 238.0
HKD3_k127_6692599_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
HKD3_k127_6692599_6 - - - - 0.00000000000000000000000000000001715 138.0
HKD3_k127_670432_0 Poly(3-hydroxyalkanoate) synthetase - - - 5.505e-263 819.0
HKD3_k127_670432_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 453.0
HKD3_k127_670432_2 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 447.0
HKD3_k127_6716208_0 ATP-dependent helicase K03579 - 3.6.4.13 0.0 1381.0
HKD3_k127_6716208_1 Flavoprotein involved in K transport - - - 4.709e-282 873.0
HKD3_k127_6716208_10 Cupin domain K11312 - - 0.00000000000000000000000000000000000000002851 155.0
HKD3_k127_6716208_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 607.0
HKD3_k127_6716208_3 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K16319,K18074 - 1.14.12.1,1.14.12.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 514.0
HKD3_k127_6716208_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 362.0
HKD3_k127_6716208_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 310.0
HKD3_k127_6716208_6 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 283.0
HKD3_k127_6716208_7 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000000001041 200.0
HKD3_k127_6716208_8 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000000000000000000000135 203.0
HKD3_k127_6716208_9 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.000000000000000000000000000000000000000000001226 171.0
HKD3_k127_6725923_0 Hydrolyzes N-terminal residues in D-amino acid- containing peptides K01266 - 3.4.11.19 4.863e-244 766.0
HKD3_k127_6725923_1 alpha/beta hydrolase fold K03821 - - 7.346e-211 662.0
HKD3_k127_6725923_10 Hydrolyzes N-terminal residues in D-amino acid- containing peptides K01266 - 3.4.11.19 0.00001995 57.0
HKD3_k127_6725923_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 480.0
HKD3_k127_6725923_3 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 393.0
HKD3_k127_6725923_4 COG3279 Response regulator of the LytR AlgR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 398.0
HKD3_k127_6725923_5 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 360.0
HKD3_k127_6725923_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000001247 137.0
HKD3_k127_6725923_7 Fe-S protein K06938 - - 0.00000000000000007373 88.0
HKD3_k127_6725923_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000004547 74.0
HKD3_k127_6725923_9 - - - - 0.0000000002118 67.0
HKD3_k127_6730391_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.327e-291 900.0
HKD3_k127_6730391_1 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 516.0
HKD3_k127_6730391_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 456.0
HKD3_k127_6730391_3 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001054 280.0
HKD3_k127_6730391_4 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000001103 160.0
HKD3_k127_6730391_5 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 0.000000000000000000000000000000000000002821 146.0
HKD3_k127_6730753_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 472.0
HKD3_k127_6730753_1 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 465.0
HKD3_k127_6730753_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 399.0
HKD3_k127_6730753_3 DoxX-like family K15977 - - 0.00000000000000000000000000000000000000000000000001002 188.0
HKD3_k127_6730753_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000001555 173.0
HKD3_k127_6730753_5 - - - - 0.000000000000000000000000000000000000000007284 164.0
HKD3_k127_6730753_6 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000004085 158.0
HKD3_k127_6730753_7 SnoaL-like domain - - - 0.00000000000000000001278 98.0
HKD3_k127_6730753_8 Isochorismatase family K08281 - 3.5.1.19 0.00000000000005954 71.0
HKD3_k127_6730753_9 - - - - 0.000000000008959 68.0
HKD3_k127_6752280_0 Aminotransferase class I and II - - - 2.821e-226 704.0
HKD3_k127_6752280_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 519.0
HKD3_k127_6752280_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 281.0
HKD3_k127_6752280_3 PFAM NnrUfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002606 280.0
HKD3_k127_6752280_4 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001565 290.0
HKD3_k127_6752280_5 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HKD3_k127_6752280_6 Isochorismatase family - - - 0.000000000000000000000000000000000000003054 154.0
HKD3_k127_6752280_8 SmpA / OmlA family - - - 0.0000000000000000000001768 112.0
HKD3_k127_6752280_9 - - - - 0.00001567 53.0
HKD3_k127_6807978_0 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 580.0
HKD3_k127_6807978_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 435.0
HKD3_k127_6821676_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 597.0
HKD3_k127_6821676_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HKD3_k127_6821676_10 cobalamin biosynthesis protein K02189 - 3.7.1.12 0.000000000000000000000000007887 120.0
HKD3_k127_6821676_11 carbohydrate kinase activity - - - 0.0000000000000000006881 100.0
HKD3_k127_6821676_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000007879 72.0
HKD3_k127_6821676_2 Precorrin-4 K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
HKD3_k127_6821676_3 Nitroreductase family K04719 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 394.0
HKD3_k127_6821676_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 325.0
HKD3_k127_6821676_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 318.0
HKD3_k127_6821676_6 Precorrin-6Y C5,15-methyltransferase K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000008407 239.0
HKD3_k127_6821676_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
HKD3_k127_6821676_8 - - - - 0.0000000000000000000000000000000002435 134.0
HKD3_k127_6821676_9 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000009708 123.0
HKD3_k127_682201_0 Periplasmic binding protein K01999 - - 3.33e-218 684.0
HKD3_k127_682201_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 497.0
HKD3_k127_682201_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000006688 145.0
HKD3_k127_6835342_0 homoserine dehydrogenase - - - 3.559e-282 869.0
HKD3_k127_6835342_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 524.0
HKD3_k127_6835342_2 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 409.0
HKD3_k127_6835342_3 Globin - - - 0.0000000000000000000000000000000000000000000000000000001092 199.0
HKD3_k127_6835342_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000003503 191.0
HKD3_k127_6835342_5 - - - - 0.00000000000000000000000000000000000000034 159.0
HKD3_k127_6840001_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 440.0
HKD3_k127_6840001_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 256.0
HKD3_k127_6840001_2 Protein conserved in bacteria K09991 - - 0.000000000000000000000000000000000000000000000000000000000000000009096 231.0
HKD3_k127_6916816_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.623e-199 623.0
HKD3_k127_6916816_1 FAD binding domain K11472 - - 7.864e-199 623.0
HKD3_k127_6942848_0 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.0 1060.0
HKD3_k127_6942848_1 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 578.0
HKD3_k127_6942848_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 531.0
HKD3_k127_6942848_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 388.0
HKD3_k127_6942848_4 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 327.0
HKD3_k127_6942848_5 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 316.0
HKD3_k127_6942848_6 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003642 267.0
HKD3_k127_696962_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1234.0
HKD3_k127_696962_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 489.0
HKD3_k127_696962_2 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 434.0
HKD3_k127_696962_3 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 415.0
HKD3_k127_696962_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 413.0
HKD3_k127_696962_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001089 273.0
HKD3_k127_696962_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000004334 223.0
HKD3_k127_696962_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000005696 148.0
HKD3_k127_7000781_0 FAD dependent oxidoreductase - - - 0.0 1489.0
HKD3_k127_7000781_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.748e-275 850.0
HKD3_k127_7000781_2 Iron-containing alcohol dehydrogenase - - - 6.108e-226 704.0
HKD3_k127_7000781_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.151e-197 627.0
HKD3_k127_7000781_4 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000003118 89.0
HKD3_k127_702226_0 transport system fused permease components - - - 8.913e-197 629.0
HKD3_k127_702226_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 544.0
HKD3_k127_702226_2 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 449.0
HKD3_k127_702226_3 membrane K08985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 446.0
HKD3_k127_7042361_0 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 4.744e-246 770.0
HKD3_k127_7042361_1 Mo-co oxidoreductase dimerisation domain - - - 2.717e-205 644.0
HKD3_k127_7042361_2 Benzoate membrane transport protein K05782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 567.0
HKD3_k127_7042361_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 521.0
HKD3_k127_7042361_5 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
HKD3_k127_7042361_6 Transcriptional - - - 0.000000000000000000000000000000000000000000000003595 173.0
HKD3_k127_7042361_8 Cytochrome c1 - - - 0.000000000000000000000000000000002688 129.0
HKD3_k127_7042361_9 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000001843 79.0
HKD3_k127_7051560_0 Phosphate transport regulator - - - 9.747e-245 771.0
HKD3_k127_7051560_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002006 292.0
HKD3_k127_7065172_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0 1185.0
HKD3_k127_7065172_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0 1034.0
HKD3_k127_7065172_2 Major Facilitator Superfamily - - - 3.304e-243 760.0
HKD3_k127_7065172_3 carboxylic acid catabolic process - - - 4.132e-237 734.0
HKD3_k127_7065172_4 HlyD membrane-fusion protein of T1SS - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 557.0
HKD3_k127_7065172_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 403.0
HKD3_k127_7065172_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 401.0
HKD3_k127_7065172_7 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 323.0
HKD3_k127_7065172_8 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 251.0
HKD3_k127_7073031_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 0.0 1236.0
HKD3_k127_7073031_1 SbmA/BacA-like family K02471 - - 0.0 1012.0
HKD3_k127_7073031_10 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000001604 162.0
HKD3_k127_7073031_12 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000003435 117.0
HKD3_k127_7073031_13 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000001027 117.0
HKD3_k127_7073031_15 Integrase core domain - - - 0.0008282 42.0
HKD3_k127_7073031_2 Sulfide dehydrogenase - - - 1.684e-222 694.0
HKD3_k127_7073031_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 467.0
HKD3_k127_7073031_4 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 376.0
HKD3_k127_7073031_5 transcriptional regulator K05800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 293.0
HKD3_k127_7073031_6 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005974 259.0
HKD3_k127_7073031_7 sulfur oxidation protein (SoxY) K17226 - - 0.000000000000000000000000000000000000000000000000000000005123 201.0
HKD3_k127_7073031_8 cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000004898 211.0
HKD3_k127_7073031_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002919 185.0
HKD3_k127_7073553_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 625.0
HKD3_k127_7073553_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 310.0
HKD3_k127_7073553_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 337.0
HKD3_k127_7073553_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000006355 226.0
HKD3_k127_7073553_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000001358 98.0
HKD3_k127_7109879_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.352e-253 786.0
HKD3_k127_7109879_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.558e-223 699.0
HKD3_k127_7109879_10 Uncharacterized protein family UPF0016 - - - 0.00007066 46.0
HKD3_k127_7109879_2 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 462.0
HKD3_k127_7109879_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 410.0
HKD3_k127_7109879_4 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 315.0
HKD3_k127_7109879_6 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000004866 162.0
HKD3_k127_7109879_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000001885 144.0
HKD3_k127_7109879_8 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000001373 140.0
HKD3_k127_7109879_9 Aha1 domain protein - - - 0.0000000000000000000000000000001377 129.0
HKD3_k127_713565_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 2.829e-245 761.0
HKD3_k127_713565_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 409.0
HKD3_k127_713565_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000008542 183.0
HKD3_k127_718166_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 9.62e-306 941.0
HKD3_k127_718166_1 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 9.928e-224 698.0
HKD3_k127_718166_2 NADH-ubiquinone oxidoreductase chain 49kDa - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 549.0
HKD3_k127_718166_3 oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
HKD3_k127_718166_4 Pentapeptide repeats (9 copies) - - - 0.0000000000000009615 83.0
HKD3_k127_7193475_0 Aminotransferase class-III K01845 - 5.4.3.8 3.206e-244 758.0
HKD3_k127_7193475_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 4.224e-228 708.0
HKD3_k127_7193475_10 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007407 255.0
HKD3_k127_7193475_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000004651 229.0
HKD3_k127_7193475_12 Response regulator receiver - - - 0.00000000000000001447 91.0
HKD3_k127_7193475_13 - - - - 0.00000000000000002775 88.0
HKD3_k127_7193475_14 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000001907 89.0
HKD3_k127_7193475_15 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18303,K21134 - - 0.00000000001318 67.0
HKD3_k127_7193475_16 Response regulator receiver - - - 0.0000004227 59.0
HKD3_k127_7193475_2 CoA-transferase family III - - - 3.871e-200 636.0
HKD3_k127_7193475_3 N-terminal domain of oxidoreductase K07119 - - 8.012e-197 617.0
HKD3_k127_7193475_4 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 603.0
HKD3_k127_7193475_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 500.0
HKD3_k127_7193475_6 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 435.0
HKD3_k127_7193475_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 394.0
HKD3_k127_7193475_8 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
HKD3_k127_7193475_9 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
HKD3_k127_7215324_0 TIGRFAM FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family K20938 - 1.14.14.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 533.0
HKD3_k127_7215324_1 of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 506.0
HKD3_k127_7215324_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 398.0
HKD3_k127_7215324_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 324.0
HKD3_k127_7215324_4 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002659 279.0
HKD3_k127_7215324_5 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001424 275.0
HKD3_k127_7215324_6 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001408 248.0
HKD3_k127_7218851_0 Psort location Cytoplasmic, score 7.50 - - - 3.248e-230 732.0
HKD3_k127_7218851_1 Major Facilitator - - - 3.571e-206 659.0
HKD3_k127_7218851_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000002725 139.0
HKD3_k127_7218851_11 - - - - 0.00000000000000000000000000000008163 131.0
HKD3_k127_7218851_13 Serine aminopeptidase, S33 - - - 0.000000000000000005887 83.0
HKD3_k127_7218851_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 595.0
HKD3_k127_7218851_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 397.0
HKD3_k127_7218851_4 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 353.0
HKD3_k127_7218851_5 COG0861 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 344.0
HKD3_k127_7218851_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
HKD3_k127_7218851_7 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 293.0
HKD3_k127_7218851_8 - - - - 0.0000000000000000000000000000000000000000000000000000001396 215.0
HKD3_k127_723572_0 Belongs to the binding-protein-dependent transport system permease family K11960 - - 8.078e-278 862.0
HKD3_k127_723572_1 Periplasmic binding protein domain K11959 - - 5.714e-263 813.0
HKD3_k127_723572_2 Belongs to the binding-protein-dependent transport system permease family K11961 - - 1.318e-202 654.0
HKD3_k127_723572_3 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 424.0
HKD3_k127_723572_4 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 397.0
HKD3_k127_723572_5 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 355.0
HKD3_k127_723572_6 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 304.0
HKD3_k127_723572_7 Hydrogenase urease accessory protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000006521 250.0
HKD3_k127_723572_8 Protein of unknown function (DUF3995) - - - 0.00000000000000000000000000000000000000000000000000000000002558 219.0
HKD3_k127_723572_9 ABC transporter K11962 - - 0.000000000000000000000000000000000000000000000000001181 187.0
HKD3_k127_7266349_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.535e-237 741.0
HKD3_k127_7266349_1 Soluble lytic murein K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 306.0
HKD3_k127_7266349_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000008365 139.0
HKD3_k127_7267776_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1976.0
HKD3_k127_7267776_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1479.0
HKD3_k127_7267776_11 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000001438 144.0
HKD3_k127_7267776_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 497.0
HKD3_k127_7267776_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 498.0
HKD3_k127_7267776_4 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 345.0
HKD3_k127_7267776_5 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 321.0
HKD3_k127_7267776_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001135 282.0
HKD3_k127_7267776_7 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008029 276.0
HKD3_k127_7267776_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004251 241.0
HKD3_k127_7267776_9 - - - - 0.0000000000000000000000000000000000000000000004406 185.0
HKD3_k127_72729_0 phosphonate metabolism K06164 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 604.0
HKD3_k127_72729_1 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 - 4.7.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 531.0
HKD3_k127_72729_2 (ABC transporter), ATP-binding K05780 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 365.0
HKD3_k127_72729_3 ABC transporter K05781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 374.0
HKD3_k127_72729_4 metal-dependent hydrolase involved in phosphonate metabolism K06162 - 3.6.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 366.0
HKD3_k127_72729_5 Bacterial phosphonate metabolism protein (PhnH) K06165 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 253.0
HKD3_k127_72729_6 Phosphonate C-P lyase system protein PhnG K06166 - 2.7.8.37 0.000000000000000000000000000000000000006683 149.0
HKD3_k127_7274220_0 Amidase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 565.0
HKD3_k127_7274220_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 465.0
HKD3_k127_7274220_2 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 292.0
HKD3_k127_7280653_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 482.0
HKD3_k127_7280653_1 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006866 256.0
HKD3_k127_7280653_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000001322 236.0
HKD3_k127_7280653_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000002287 216.0
HKD3_k127_7306164_0 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 581.0
HKD3_k127_7306164_1 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 421.0
HKD3_k127_7315831_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 463.0
HKD3_k127_7315831_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 361.0
HKD3_k127_7315831_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000144 67.0
HKD3_k127_7329881_0 FAD linked oxidase domain protein - - - 1.246e-282 878.0
HKD3_k127_7329881_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 2.393e-264 825.0
HKD3_k127_7329881_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 325.0
HKD3_k127_7329881_12 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 283.0
HKD3_k127_7329881_13 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004991 269.0
HKD3_k127_7329881_15 Glutathione S-transferase K11209 - - 0.00000000000000000000004349 98.0
HKD3_k127_7329881_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.231e-255 790.0
HKD3_k127_7329881_3 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 605.0
HKD3_k127_7329881_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 606.0
HKD3_k127_7329881_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 587.0
HKD3_k127_7329881_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 579.0
HKD3_k127_7329881_7 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 493.0
HKD3_k127_7329881_8 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 490.0
HKD3_k127_7329881_9 Glutathione S-transferase K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 437.0
HKD3_k127_7331609_0 amidohydrolase - - - 2.897e-215 671.0
HKD3_k127_7331609_1 DinB superfamily - - - 6.895e-194 611.0
HKD3_k127_7331609_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
HKD3_k127_7331609_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 488.0
HKD3_k127_7331609_4 ubiquitin protein ligase binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 403.0
HKD3_k127_7331609_5 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 349.0
HKD3_k127_7331609_6 2-Nitropropane dioxygenase - - - 0.0000000000000000000000000000000000000000001375 172.0
HKD3_k127_7331609_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000312 125.0
HKD3_k127_7331609_8 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000001618 120.0
HKD3_k127_7331609_9 Protein of unknown function (DUF1328) - - - 0.000000000000000001032 91.0
HKD3_k127_7333180_0 signal transduction histidine kinase K07636 - 2.7.13.3 3.257e-239 745.0
HKD3_k127_7333180_1 Radical SAM K06937 - - 2.638e-212 669.0
HKD3_k127_7333180_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 337.0
HKD3_k127_7333180_3 Autotransporter beta-domain - - - 0.00000000003233 65.0
HKD3_k127_7333180_4 Autotransporter beta-domain - - - 0.00000000004993 72.0
HKD3_k127_7333180_5 pathogenesis - - - 0.000004811 54.0
HKD3_k127_7342083_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 444.0
HKD3_k127_7342083_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002501 225.0
HKD3_k127_7342083_2 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000002029 177.0
HKD3_k127_7342083_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000001606 97.0
HKD3_k127_7363147_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 377.0
HKD3_k127_7363147_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 337.0
HKD3_k127_7363147_2 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008986 266.0
HKD3_k127_7363147_3 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000006557 262.0
HKD3_k127_7378298_0 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbD K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 426.0
HKD3_k127_7378298_1 carbohydrate binding K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 424.0
HKD3_k127_7378298_2 PFAM PepSY-associated TM helix domain protein K09939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 354.0
HKD3_k127_7378298_3 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 340.0
HKD3_k127_7378298_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 289.0
HKD3_k127_7378298_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001202 275.0
HKD3_k127_7378298_6 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
HKD3_k127_7378298_7 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
HKD3_k127_7378298_8 COG1629 Outer membrane receptor proteins, mostly Fe transport K16090 - - 0.0000000000000000000000001469 106.0
HKD3_k127_7381326_0 Adenylate cyclase K01768 - 4.6.1.1 1.513e-270 842.0
HKD3_k127_7381326_1 Capsular polysaccharide biosynthesis protein CapK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 403.0
HKD3_k127_7381326_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 357.0
HKD3_k127_7381326_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000005642 147.0
HKD3_k127_7381326_4 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000002615 145.0
HKD3_k127_7393249_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.237e-236 732.0
HKD3_k127_7393249_1 Peptidase dimerisation domain K01295 - 3.4.17.11 1.326e-224 698.0
HKD3_k127_7393249_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 563.0
HKD3_k127_7393249_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 450.0
HKD3_k127_7393249_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 373.0
HKD3_k127_7393249_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 331.0
HKD3_k127_7393249_6 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006186 272.0
HKD3_k127_7393249_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 262.0
HKD3_k127_7393249_8 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004844 235.0
HKD3_k127_7393249_9 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000009784 122.0
HKD3_k127_7407511_0 COG1042 Acyl-CoA synthetase (NDP forming) - - - 0.0 1139.0
HKD3_k127_7407511_1 Psort location Cytoplasmic, score 7.50 - - - 4.169e-223 696.0
HKD3_k127_7407511_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 537.0
HKD3_k127_7407511_3 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 397.0
HKD3_k127_7407511_4 cation efflux K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 380.0
HKD3_k127_7407511_5 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
HKD3_k127_7407511_6 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
HKD3_k127_7407511_7 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000009191 157.0
HKD3_k127_7407511_9 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.000000000002866 66.0
HKD3_k127_741029_0 ATPase involved in DNA repair K13924 - 2.1.1.80,3.1.1.61 3.569e-273 880.0
HKD3_k127_741029_1 mitochondrial gene expression - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 585.0
HKD3_k127_741029_2 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 542.0
HKD3_k127_741029_3 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 351.0
HKD3_k127_741029_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002444 259.0
HKD3_k127_741029_5 COG0457 FOG TPR repeat - - - 0.000000004617 62.0
HKD3_k127_7412714_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 347.0
HKD3_k127_7412714_1 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000001063 165.0
HKD3_k127_7412714_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000002991 95.0
HKD3_k127_7417715_0 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 449.0
HKD3_k127_7417715_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 339.0
HKD3_k127_7421268_0 P-aminobenzoate N-oxygenase AurF - - - 9.092e-222 690.0
HKD3_k127_7421268_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 508.0
HKD3_k127_7421268_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 424.0
HKD3_k127_7421268_3 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000004394 199.0
HKD3_k127_7421268_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000005938 144.0
HKD3_k127_7421268_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000253 128.0
HKD3_k127_7428302_0 Adenylate cyclase K01768 - 4.6.1.1 2.755e-305 949.0
HKD3_k127_7428302_1 belongs to the bacterial solute-binding protein 3 family K02030 - - 3.597e-220 699.0
HKD3_k127_7428302_2 Belongs to the amidase family K01426 - 3.5.1.4 4.196e-211 664.0
HKD3_k127_7428302_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
HKD3_k127_7428302_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004169 267.0
HKD3_k127_7428302_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003608 259.0
HKD3_k127_7428302_6 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001753 229.0
HKD3_k127_7428302_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000775 237.0
HKD3_k127_7428302_8 Protein tyrosine kinase - - - 0.000000009692 64.0
HKD3_k127_7428302_9 acetyl-coa acetyltransferase - - - 0.0000002703 55.0
HKD3_k127_7436472_0 Luciferase-like monooxygenase - - - 7.365e-255 787.0
HKD3_k127_7436472_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 553.0
HKD3_k127_7436472_10 decarboxylase - - - 0.0000000000001874 76.0
HKD3_k127_7436472_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 448.0
HKD3_k127_7436472_3 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 311.0
HKD3_k127_7436472_4 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
HKD3_k127_7436472_5 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002775 249.0
HKD3_k127_7436472_6 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000004691 229.0
HKD3_k127_7436472_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000000000000000005349 208.0
HKD3_k127_7436472_8 FAD binding domain K00480 - 1.14.13.1 0.0000000000000000000000000000000000000114 147.0
HKD3_k127_7436472_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.00000000000000000000000000000000003204 135.0
HKD3_k127_7439238_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.634e-304 937.0
HKD3_k127_7439238_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 1.65e-276 857.0
HKD3_k127_7439238_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 518.0
HKD3_k127_7439238_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 406.0
HKD3_k127_7439238_4 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000001456 75.0
HKD3_k127_7445272_0 Sulfatase K01133 - 3.1.6.6 3.665e-307 949.0
HKD3_k127_7445272_1 Periplasmic binding protein K01999 - - 1.935e-214 674.0
HKD3_k127_7445272_2 cellulose binding - - - 2.634e-194 609.0
HKD3_k127_7445272_3 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 542.0
HKD3_k127_7445272_4 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 451.0
HKD3_k127_7445272_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 360.0
HKD3_k127_7445272_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001275 239.0
HKD3_k127_7445272_7 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 0.00000000000002142 74.0
HKD3_k127_7452008_0 Serine/threonine phosphatases, family 2C, catalytic domain - - - 1.464e-259 811.0
HKD3_k127_7452008_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.028e-204 640.0
HKD3_k127_7452008_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 386.0
HKD3_k127_7452008_3 Formate/nitrite transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000005584 226.0
HKD3_k127_7454558_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008501 299.0
HKD3_k127_7454558_1 Family of unknown function (DUF5309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003139 240.0
HKD3_k127_7454558_3 - - - - 0.00000002884 64.0
HKD3_k127_7467869_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1374.0
HKD3_k127_7467869_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1217.0
HKD3_k127_7467869_10 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000000000000000000005352 149.0
HKD3_k127_7467869_11 transcriptional regulator - - - 0.0000000000000000000866 97.0
HKD3_k127_7467869_2 Domain of unknown function (DUF4139) - - - 0.0 1014.0
HKD3_k127_7467869_3 Probable molybdopterin binding domain K07141 - 2.7.7.76 7.653e-296 927.0
HKD3_k127_7467869_4 VWA domain containing CoxE-like protein K07161 - - 4.313e-243 754.0
HKD3_k127_7467869_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 2.375e-223 707.0
HKD3_k127_7467869_6 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 563.0
HKD3_k127_7467869_7 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 382.0
HKD3_k127_7467869_8 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000005523 232.0
HKD3_k127_7467869_9 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
HKD3_k127_7497844_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1772.0
HKD3_k127_7497844_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 544.0
HKD3_k127_7497844_2 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003491 252.0
HKD3_k127_7501065_0 Major Facilitator Superfamily K03446 - - 1.67e-297 917.0
HKD3_k127_7501065_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.973e-276 857.0
HKD3_k127_7501065_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 481.0
HKD3_k127_7514915_0 Luciferase-like monooxygenase - - - 4.791e-213 663.0
HKD3_k127_7514915_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 412.0
HKD3_k127_7514915_2 Chain length determinant protein K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 300.0
HKD3_k127_7514915_3 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000004356 220.0
HKD3_k127_7524398_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 1.426e-298 921.0
HKD3_k127_7524398_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.883e-236 746.0
HKD3_k127_7524398_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 538.0
HKD3_k127_7524398_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 479.0
HKD3_k127_7524398_4 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 282.0
HKD3_k127_7524398_5 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006353 269.0
HKD3_k127_7524398_6 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
HKD3_k127_7524398_7 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000000000000000000000000000007826 213.0
HKD3_k127_7524398_8 ChaB K06197 - - 0.00000000000000000000000199 105.0
HKD3_k127_7524441_0 beta (1-6) glucans synthase - - - 0.0 1132.0
HKD3_k127_7524441_1 Protein of unknown function (DUF2817) - - - 9.538e-218 678.0
HKD3_k127_7524441_2 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 5.912e-198 618.0
HKD3_k127_7524441_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 456.0
HKD3_k127_7524441_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001617 256.0
HKD3_k127_7524441_5 dehydratase - - - 0.0000000000003255 69.0
HKD3_k127_7524441_6 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.00001153 49.0
HKD3_k127_7525623_0 Na+/Pi-cotransporter K03324 - - 4.856e-268 834.0
HKD3_k127_7525623_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.169e-243 755.0
HKD3_k127_7525623_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 2.303e-213 666.0
HKD3_k127_7525623_3 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 484.0
HKD3_k127_7525623_4 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 336.0
HKD3_k127_7525623_5 FAD dependent oxidoreductase - - - 0.0000000000003255 69.0
HKD3_k127_7567312_0 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 469.0
HKD3_k127_7567312_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
HKD3_k127_7567312_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
HKD3_k127_7567312_3 Exodeoxyribonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007367 252.0
HKD3_k127_7567312_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000771 76.0
HKD3_k127_7576132_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 522.0
HKD3_k127_7576132_1 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 448.0
HKD3_k127_7576132_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001838 179.0
HKD3_k127_7576132_11 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000006247 119.0
HKD3_k127_7576132_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 403.0
HKD3_k127_7576132_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 359.0
HKD3_k127_7576132_4 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 331.0
HKD3_k127_7576132_5 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001787 284.0
HKD3_k127_7576132_6 universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003879 263.0
HKD3_k127_7576132_7 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009664 239.0
HKD3_k127_7576132_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000445 228.0
HKD3_k127_7576132_9 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000001525 197.0
HKD3_k127_7595290_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 2557.0
HKD3_k127_7595290_1 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
HKD3_k127_7595290_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000003099 123.0
HKD3_k127_7609724_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1363.0
HKD3_k127_7609724_1 Hydantoinase B/oxoprolinase - - - 0.0 1069.0
HKD3_k127_7609724_11 CoA-transferase family III - - - 0.00000000000005549 77.0
HKD3_k127_7609724_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 9.301e-255 791.0
HKD3_k127_7609724_3 Luciferase-like monooxygenase - - - 1.41e-249 773.0
HKD3_k127_7609724_4 acetyl-coa acetyltransferase - - - 1.049e-243 754.0
HKD3_k127_7609724_5 oxidase, subunit K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 596.0
HKD3_k127_7609724_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 548.0
HKD3_k127_7609724_7 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 522.0
HKD3_k127_7609724_8 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 398.0
HKD3_k127_7609724_9 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001165 263.0
HKD3_k127_7618550_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 2.153e-289 903.0
HKD3_k127_7618550_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.674e-272 842.0
HKD3_k127_7618550_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 513.0
HKD3_k127_7618550_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 466.0
HKD3_k127_7618550_4 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 453.0
HKD3_k127_7618550_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 370.0
HKD3_k127_7618550_6 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 330.0
HKD3_k127_7618550_7 Protein of unknown function (DUF1007) K00937,K06925 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 333.0
HKD3_k127_7618550_9 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000000000000000000000000000006266 181.0
HKD3_k127_763918_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 584.0
HKD3_k127_763918_1 Glucose / Sorbosone dehydrogenase K21430 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 570.0
HKD3_k127_763918_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 422.0
HKD3_k127_763918_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000003404 149.0
HKD3_k127_763918_4 Maf-like protein K06287 - - 0.00000000000000002839 82.0
HKD3_k127_7655682_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1006.0
HKD3_k127_7655682_1 Adenylate cyclase K01768 - 4.6.1.1 1.938e-266 837.0
HKD3_k127_7655682_10 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000001639 232.0
HKD3_k127_7655682_11 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000001256 222.0
HKD3_k127_7655682_12 Carbohydrate-selective porin, OprB family K16080 - - 0.000000000000000000000000000000000000000000000000005978 182.0
HKD3_k127_7655682_13 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000007546 169.0
HKD3_k127_7655682_2 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 542.0
HKD3_k127_7655682_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 547.0
HKD3_k127_7655682_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 509.0
HKD3_k127_7655682_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 494.0
HKD3_k127_7655682_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 454.0
HKD3_k127_7655682_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 405.0
HKD3_k127_7655682_8 Major intrinsic protein K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 360.0
HKD3_k127_7655682_9 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 357.0
HKD3_k127_7675715_0 FAD dependent oxidoreductase - - - 2.441e-213 668.0
HKD3_k127_7675715_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000519 257.0
HKD3_k127_7680990_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 1.667e-228 710.0
HKD3_k127_7680990_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000668 261.0
HKD3_k127_7756201_0 Acyl-CoA dehydrogenase, middle domain - - - 1.157e-223 694.0
HKD3_k127_7756201_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.046e-217 678.0
HKD3_k127_7756201_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 392.0
HKD3_k127_7756201_3 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006117 271.0
HKD3_k127_7756201_4 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000000000000000000000000004636 205.0
HKD3_k127_7756201_5 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000000000000000000000002645 212.0
HKD3_k127_7756201_6 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000004974 95.0
HKD3_k127_7762473_0 oligoendopeptidase F K08602 - - 0.0 1094.0
HKD3_k127_7762473_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.513e-319 980.0
HKD3_k127_7762473_2 ABC1 family - - - 3.52e-259 802.0
HKD3_k127_7762473_3 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 535.0
HKD3_k127_7762473_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 373.0
HKD3_k127_7762473_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
HKD3_k127_7762473_6 Vancomycin high temperature exclusion protein K03748 - - 0.00000000000000000000000000000000000000000000000000000000002925 232.0
HKD3_k127_7762473_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000008262 187.0
HKD3_k127_7762473_8 GAF domain - - - 0.000000000000000000000000000000000000008113 156.0
HKD3_k127_7762473_9 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000000008563 139.0
HKD3_k127_7769703_0 Receptor family ligand binding region - - - 5.782e-202 637.0
HKD3_k127_7769703_1 - - - - 5.214e-196 623.0
HKD3_k127_7769703_10 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000463 177.0
HKD3_k127_7769703_11 Cupin domain - - - 0.00000000000000000000000000000000000000000000001592 183.0
HKD3_k127_7769703_12 Redoxin - - - 0.00000000000000000000000000000000004716 144.0
HKD3_k127_7769703_13 DoxX K15977 - - 0.0000000000000000000000000000000001484 143.0
HKD3_k127_7769703_14 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000004207 130.0
HKD3_k127_7769703_15 integral membrane protein - - - 0.0000000000000000000007638 98.0
HKD3_k127_7769703_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 510.0
HKD3_k127_7769703_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 505.0
HKD3_k127_7769703_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 475.0
HKD3_k127_7769703_5 Major Facilitator Superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 452.0
HKD3_k127_7769703_6 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 426.0
HKD3_k127_7769703_7 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 364.0
HKD3_k127_7769703_8 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 304.0
HKD3_k127_7769703_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004008 266.0
HKD3_k127_7776923_0 Enoyl-CoA hydratase/isomerase - - - 0.0 1028.0
HKD3_k127_7776923_1 benzoyl-CoA oxygenase - - - 3.107e-288 888.0
HKD3_k127_7776923_10 conserved protein, contains double-stranded beta-helix domain - - - 0.0009028 47.0
HKD3_k127_7776923_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 4.49e-220 692.0
HKD3_k127_7776923_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 598.0
HKD3_k127_7776923_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 556.0
HKD3_k127_7776923_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 517.0
HKD3_k127_7776923_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 411.0
HKD3_k127_7776923_7 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 323.0
HKD3_k127_7776923_8 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 286.0
HKD3_k127_7776923_9 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.00000005565 55.0
HKD3_k127_778448_0 Patatin phospholipase K07001 - - 6.673e-195 613.0
HKD3_k127_778448_1 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 484.0
HKD3_k127_778448_2 KR domain K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 453.0
HKD3_k127_778448_3 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 421.0
HKD3_k127_778448_4 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 324.0
HKD3_k127_778448_5 chlorophyll binding - - - 0.00000000000004987 83.0
HKD3_k127_7789384_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 462.0
HKD3_k127_7789384_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 399.0
HKD3_k127_7789384_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
HKD3_k127_7789384_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 267.0
HKD3_k127_7789384_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000004757 211.0
HKD3_k127_7789384_5 Globin - - - 0.000000000000000000000000000000000000000000000000165 183.0
HKD3_k127_7795283_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 1.54e-197 621.0
HKD3_k127_7795283_1 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 532.0
HKD3_k127_7795283_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 486.0
HKD3_k127_7795283_3 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 270.0
HKD3_k127_7796522_0 III protein, CoA-transferase family - - - 1.422e-233 727.0
HKD3_k127_7796522_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 564.0
HKD3_k127_7796522_2 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 490.0
HKD3_k127_7796522_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 355.0
HKD3_k127_7796522_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000007145 232.0
HKD3_k127_7796522_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000003849 149.0
HKD3_k127_7796522_6 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000305 75.0
HKD3_k127_780237_0 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.126e-311 970.0
HKD3_k127_780237_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 7.623e-205 639.0
HKD3_k127_780237_2 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 541.0
HKD3_k127_780237_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
HKD3_k127_7830729_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1541.0
HKD3_k127_7830729_1 Amidohydrolase family - - - 0.0 1028.0
HKD3_k127_7830729_2 Pyridoxal-dependent decarboxylase conserved domain - - - 6.716e-195 618.0
HKD3_k127_7830729_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 575.0
HKD3_k127_7830729_4 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HKD3_k127_7830729_5 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 301.0
HKD3_k127_7830729_6 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004695 274.0
HKD3_k127_7830729_8 Putative peptidoglycan binding domain - - - 0.000006962 53.0
HKD3_k127_7855245_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.146e-279 872.0
HKD3_k127_7855245_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 541.0
HKD3_k127_7855245_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 449.0
HKD3_k127_7855245_3 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 426.0
HKD3_k127_7855245_4 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007392 251.0
HKD3_k127_7855245_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000001436 231.0
HKD3_k127_7855245_6 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000536 136.0
HKD3_k127_7855245_7 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000001988 139.0
HKD3_k127_7856997_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0 1005.0
HKD3_k127_7856997_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 536.0
HKD3_k127_7856997_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 406.0
HKD3_k127_7856997_3 WHG domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 380.0
HKD3_k127_7856997_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002544 286.0
HKD3_k127_7856997_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HKD3_k127_7856997_6 CreA protein K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
HKD3_k127_7856997_7 Protein of unknown function (DUF2852) - - - 0.000000000000000000000000000000000000000000000000000000000000009822 218.0
HKD3_k127_7885084_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 419.0
HKD3_k127_7885084_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001503 218.0
HKD3_k127_7885084_2 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000005863 185.0
HKD3_k127_790093_0 monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 511.0
HKD3_k127_790093_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 462.0
HKD3_k127_790093_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 404.0
HKD3_k127_790093_3 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 344.0
HKD3_k127_790093_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 331.0
HKD3_k127_790394_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 1.412e-292 915.0
HKD3_k127_790394_1 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 6.463e-246 767.0
HKD3_k127_790394_10 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 314.0
HKD3_k127_790394_11 Belongs to the Fur family K09823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 309.0
HKD3_k127_790394_12 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002741 273.0
HKD3_k127_790394_13 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000005765 257.0
HKD3_k127_790394_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000000000009811 245.0
HKD3_k127_790394_15 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000000000003289 206.0
HKD3_k127_790394_2 Major Facilitator Superfamily - - - 2.226e-198 623.0
HKD3_k127_790394_3 Cysteine synthase K01738 - 2.5.1.47 4.984e-197 629.0
HKD3_k127_790394_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 542.0
HKD3_k127_790394_5 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 527.0
HKD3_k127_790394_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 439.0
HKD3_k127_790394_7 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 424.0
HKD3_k127_790394_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 395.0
HKD3_k127_790394_9 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 348.0
HKD3_k127_7916002_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 3.897e-270 850.0
HKD3_k127_7916002_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 524.0
HKD3_k127_7938149_0 ATPase with chaperone activity K07391 - - 9.737e-286 900.0
HKD3_k127_7938149_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 387.0
HKD3_k127_7938149_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000005736 270.0
HKD3_k127_7938149_3 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000003726 112.0
HKD3_k127_7938149_4 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000001891 81.0
HKD3_k127_7938149_5 PFAM pyridoxamine 5-phosphate oxidase-related FMN-binding - - - 0.0000005972 53.0
HKD3_k127_7938149_6 PFAM Uncharacterised protein family UPF0150 - - - 0.00001179 52.0
HKD3_k127_7938149_7 ATPase with chaperone activity K07391 - - 0.0003987 44.0
HKD3_k127_7938820_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.838e-244 761.0
HKD3_k127_7938820_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 6.67e-237 742.0
HKD3_k127_7938820_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 365.0
HKD3_k127_7938820_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001911 284.0
HKD3_k127_7938820_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD3_k127_7938820_5 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000003384 138.0
HKD3_k127_7938820_6 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000009708 123.0
HKD3_k127_798506_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.856e-305 944.0
HKD3_k127_798506_1 GTP cyclohydrolase II activity - - - 1.192e-260 805.0
HKD3_k127_798506_10 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000004114 224.0
HKD3_k127_798506_11 protein conserved in bacteria K09796 - - 0.00000000000000000000000000000000000000000000000000000000000006216 221.0
HKD3_k127_798506_12 Small multidrug resistance protein K11741 - - 0.0000000000000000000000000000000000000000000000000001381 192.0
HKD3_k127_798506_13 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000002101 191.0
HKD3_k127_798506_14 - - - - 0.000000000000000000000000000000000000000000002486 166.0
HKD3_k127_798506_16 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000001024 127.0
HKD3_k127_798506_17 KR domain - - - 0.000000007043 57.0
HKD3_k127_798506_18 - - - - 0.00003161 49.0
HKD3_k127_798506_19 - - - - 0.00003435 52.0
HKD3_k127_798506_2 Protein of unknown function (DUF1688) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 612.0
HKD3_k127_798506_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 598.0
HKD3_k127_798506_4 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 587.0
HKD3_k127_798506_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 539.0
HKD3_k127_798506_6 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 408.0
HKD3_k127_798506_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
HKD3_k127_798506_8 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HKD3_k127_798506_9 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003074 238.0
HKD3_k127_8005079_0 Beta-lactamase - - - 9.196e-237 735.0
HKD3_k127_8005079_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 552.0
HKD3_k127_8005079_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 341.0
HKD3_k127_8005079_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000009475 166.0
HKD3_k127_8047587_0 TonB dependent receptor - - - 1.06e-310 967.0
HKD3_k127_8047587_1 Epoxide hydrolase N terminus K01253 - 3.3.2.9 5.643e-245 764.0
HKD3_k127_8047587_10 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 403.0
HKD3_k127_8047587_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000016 308.0
HKD3_k127_8047587_12 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001767 266.0
HKD3_k127_8047587_13 Protein of unknown function (DUF4239) - - - 0.0000000000000000000000000000000000000003365 160.0
HKD3_k127_8047587_14 YjbR - - - 0.00000000000000000000000000005077 128.0
HKD3_k127_8047587_15 GIY-YIG catalytic domain - - - 0.000000000000000008548 90.0
HKD3_k127_8047587_2 Mg2 and Co2 transporter CorB - - - 1.12e-214 675.0
HKD3_k127_8047587_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 1.677e-197 630.0
HKD3_k127_8047587_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 558.0
HKD3_k127_8047587_6 PFAM Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 524.0
HKD3_k127_8047587_7 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006333 499.0
HKD3_k127_8047587_8 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 480.0
HKD3_k127_8047587_9 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 452.0
HKD3_k127_805667_0 Binding-protein-dependent transport system inner membrane component K02050 - - 1.059e-295 915.0
HKD3_k127_805667_1 C-terminal AAA-associated domain K02049 - - 3.248e-240 746.0
HKD3_k127_805667_10 Domain of unknown function (DUF305) - - - 0.0000000000000000000000000000000002256 137.0
HKD3_k127_805667_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000118 120.0
HKD3_k127_805667_12 AntiSigma factor - - - 0.00000000000000000000001233 110.0
HKD3_k127_805667_13 - - - - 0.000000000000000001146 91.0
HKD3_k127_805667_14 transcriptional regulator - - - 0.000000000000000003918 88.0
HKD3_k127_805667_15 Transposase, Mutator family K07493 - - 0.00000000003562 71.0
HKD3_k127_805667_16 MerT mercuric transport protein - - - 0.0000000007761 65.0
HKD3_k127_805667_17 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000009504 64.0
HKD3_k127_805667_2 40-residue yvtn family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 596.0
HKD3_k127_805667_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 531.0
HKD3_k127_805667_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
HKD3_k127_805667_5 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001675 246.0
HKD3_k127_805667_6 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
HKD3_k127_805667_7 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001742 250.0
HKD3_k127_805667_8 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000001047 153.0
HKD3_k127_805667_9 helix_turn_helix, mercury resistance K08365 - - 0.0000000000000000000000000000000000004681 151.0
HKD3_k127_805729_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 2.962e-317 974.0
HKD3_k127_805729_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000188 252.0
HKD3_k127_805729_2 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000019 138.0
HKD3_k127_8059430_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1629.0
HKD3_k127_8059430_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 468.0
HKD3_k127_8059430_10 Asp Glu hydantoin racemase - - - 0.00000002261 63.0
HKD3_k127_8059430_2 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 412.0
HKD3_k127_8059430_3 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 421.0
HKD3_k127_8059430_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 300.0
HKD3_k127_8059430_5 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 306.0
HKD3_k127_8059430_6 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000276 270.0
HKD3_k127_8059430_7 phosphatase activity K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
HKD3_k127_8059430_9 transport, permease protein K09690 - - 0.0000000001736 72.0
HKD3_k127_8077654_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 558.0
HKD3_k127_8077654_1 transport systems, ATPase components K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 440.0
HKD3_k127_8077654_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 352.0
HKD3_k127_8098564_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1129.0
HKD3_k127_8098564_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1050.0
HKD3_k127_8098564_2 acetyl-coa acetyltransferase K00626 - 2.3.1.9 2.184e-291 900.0
HKD3_k127_8098564_3 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 9.901e-220 685.0
HKD3_k127_8098564_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 542.0
HKD3_k127_8098564_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 467.0
HKD3_k127_8098564_6 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 403.0
HKD3_k127_8098564_7 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 375.0
HKD3_k127_8098564_8 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000001911 191.0
HKD3_k127_8180887_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 428.0
HKD3_k127_8180887_1 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 394.0
HKD3_k127_8180887_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 393.0
HKD3_k127_8180887_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 322.0
HKD3_k127_8180887_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000004043 231.0
HKD3_k127_8180887_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000001665 123.0
HKD3_k127_8196827_0 Luciferase-like monooxygenase - - - 1.538e-246 766.0
HKD3_k127_8196827_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 598.0
HKD3_k127_8196827_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 494.0
HKD3_k127_8196827_3 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 382.0
HKD3_k127_8196827_4 Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001157 292.0
HKD3_k127_8196827_5 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000001224 165.0
HKD3_k127_8196827_6 - - - - 0.000000000592 67.0
HKD3_k127_8196827_7 - - - - 0.00000006023 55.0
HKD3_k127_8204303_0 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 3.095e-213 664.0
HKD3_k127_8204303_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
HKD3_k127_8204303_2 16S RNA G1207 methylase RsmC K00564 - 2.1.1.172 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 437.0
HKD3_k127_8204303_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 433.0
HKD3_k127_8204303_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
HKD3_k127_8204303_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 409.0
HKD3_k127_8204303_6 branched-chain amino acid K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 356.0
HKD3_k127_8204303_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 298.0
HKD3_k127_8208419_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.061e-236 734.0
HKD3_k127_8208419_1 Protein of unknown function (DUF3419) - - - 1.115e-206 649.0
HKD3_k127_8208419_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 543.0
HKD3_k127_8208419_3 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 521.0
HKD3_k127_8208419_4 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 373.0
HKD3_k127_8208419_5 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002131 292.0
HKD3_k127_8220924_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 582.0
HKD3_k127_8220924_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 482.0
HKD3_k127_8220924_2 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 376.0
HKD3_k127_8220924_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004201 221.0
HKD3_k127_8220924_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000001719 173.0
HKD3_k127_8220924_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000008697 150.0
HKD3_k127_82342_0 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 491.0
HKD3_k127_82342_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 473.0
HKD3_k127_82342_10 - - - - 0.0000000000000000000000000729 115.0
HKD3_k127_82342_12 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.00000000002488 66.0
HKD3_k127_82342_14 - - - - 0.0007284 46.0
HKD3_k127_82342_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 489.0
HKD3_k127_82342_3 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 430.0
HKD3_k127_82342_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 414.0
HKD3_k127_82342_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 331.0
HKD3_k127_82342_6 LTXXQ motif family protein - - - 0.000000000000000000000000000000000000000000000000000006578 196.0
HKD3_k127_82342_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000003993 188.0
HKD3_k127_82342_8 YHS domain protein - - - 0.00000000000000000000000000000008475 131.0
HKD3_k127_82342_9 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000001088 112.0
HKD3_k127_8253569_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.663e-247 767.0
HKD3_k127_8253569_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009619 483.0
HKD3_k127_8253569_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 438.0
HKD3_k127_8253569_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 437.0
HKD3_k127_8253569_4 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 394.0
HKD3_k127_8253569_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000008807 188.0
HKD3_k127_8253569_7 Septum formation initiator - - - 0.0000000000000000000000000000000000000000000000000001482 186.0
HKD3_k127_8253569_8 transposase activity - - - 0.0000000000000000000000000000000001494 147.0
HKD3_k127_8253569_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000004276 110.0
HKD3_k127_8284204_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 527.0
HKD3_k127_8284204_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 502.0
HKD3_k127_8284204_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
HKD3_k127_8284204_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000003873 149.0
HKD3_k127_8284204_4 amidohydrolase 2 - - - 0.0000000000000000000000001035 106.0
HKD3_k127_8296303_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 1.275e-198 622.0
HKD3_k127_8296303_1 RND efflux system, outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 614.0
HKD3_k127_8296303_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 561.0
HKD3_k127_8305632_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 2.715e-244 762.0
HKD3_k127_8305632_1 Belongs to the GARS family K01945 - 6.3.4.13 3.838e-228 711.0
HKD3_k127_8305632_10 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000004554 194.0
HKD3_k127_8305632_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
HKD3_k127_8305632_12 PIN domain - - - 0.0000000000000000000000000009599 117.0
HKD3_k127_8305632_13 positive regulation of growth - - - 0.00000000004445 66.0
HKD3_k127_8305632_2 Metallo-beta-lactamase superfamily - - - 3.127e-225 700.0
HKD3_k127_8305632_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 7.42e-211 664.0
HKD3_k127_8305632_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.984e-195 622.0
HKD3_k127_8305632_5 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 571.0
HKD3_k127_8305632_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 507.0
HKD3_k127_8305632_7 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 446.0
HKD3_k127_8305632_8 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 437.0
HKD3_k127_8305632_9 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 372.0
HKD3_k127_8308875_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 8.62e-317 975.0
HKD3_k127_8308875_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.326e-227 726.0
HKD3_k127_8308875_10 Flavodoxin-like fold K00355 - 1.6.5.2 0.00001816 55.0
HKD3_k127_8308875_2 Ureidoglycolate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 376.0
HKD3_k127_8308875_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 368.0
HKD3_k127_8308875_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 327.0
HKD3_k127_8308875_5 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 290.0
HKD3_k127_8308875_6 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002899 140.0
HKD3_k127_8308875_7 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000001046 132.0
HKD3_k127_8308875_9 - - - - 0.000000000000000000002984 102.0
HKD3_k127_8338466_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
HKD3_k127_8338466_1 2OG-Fe dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 392.0
HKD3_k127_8338466_2 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 409.0
HKD3_k127_8338466_3 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 331.0
HKD3_k127_8338466_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000002075 207.0
HKD3_k127_8338466_5 Sugar (and other) transporter K03762 - - 0.00000000000002414 75.0
HKD3_k127_8350234_0 Chaperone SurA K03771 - 5.2.1.8 1.478e-195 618.0
HKD3_k127_8350234_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 548.0
HKD3_k127_8350234_10 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001973 274.0
HKD3_k127_8350234_11 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002828 216.0
HKD3_k127_8350234_12 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000001893 214.0
HKD3_k127_8350234_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000002079 203.0
HKD3_k127_8350234_14 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000006975 87.0
HKD3_k127_8350234_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 545.0
HKD3_k127_8350234_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 496.0
HKD3_k127_8350234_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 420.0
HKD3_k127_8350234_5 GHMP kinases N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 366.0
HKD3_k127_8350234_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 357.0
HKD3_k127_8350234_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 293.0
HKD3_k127_8350234_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002277 281.0
HKD3_k127_8350234_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005395 277.0
HKD3_k127_8356092_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 2.945e-302 953.0
HKD3_k127_8356092_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K19745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 587.0
HKD3_k127_8356092_2 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 544.0
HKD3_k127_8356092_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 501.0
HKD3_k127_8356092_4 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 503.0
HKD3_k127_8356092_5 transcriptional regulator K05818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009376 302.0
HKD3_k127_8356092_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005526 275.0
HKD3_k127_8356092_7 - - - - 0.000000000000000000001743 96.0
HKD3_k127_8357571_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0 1180.0
HKD3_k127_8357571_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.119e-255 787.0
HKD3_k127_8357571_10 - - - - 0.00000000000000000000000000000000002677 138.0
HKD3_k127_8357571_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000001201 91.0
HKD3_k127_8357571_12 Bacterial protein of unknown function (DUF839) K07093 - - 0.000009778 56.0
HKD3_k127_8357571_2 CoA-transferase family III - - - 1.521e-235 733.0
HKD3_k127_8357571_3 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 511.0
HKD3_k127_8357571_4 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 422.0
HKD3_k127_8357571_5 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 356.0
HKD3_k127_8357571_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000001321 214.0
HKD3_k127_8357571_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD3_k127_8357571_8 Formate/nitrite transporter - - - 0.00000000000000000000000000000000000000000000001679 174.0
HKD3_k127_8357571_9 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000000000000000001935 172.0
HKD3_k127_8372365_0 Major Facilitator Superfamily K02575 - - 0.0 1427.0
HKD3_k127_8372365_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.0000000000000000000000000000000000000000000000000000000000131 208.0
HKD3_k127_8395385_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 6.23e-322 989.0
HKD3_k127_8395385_1 Flavoprotein involved in K transport K03379,K21730 - 1.14.13.160,1.14.13.22 1.875e-232 733.0
HKD3_k127_8395385_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 357.0
HKD3_k127_8395385_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 294.0
HKD3_k127_8395385_12 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001582 283.0
HKD3_k127_8395385_2 Periplasmic binding protein domain - - - 5.96e-228 732.0
HKD3_k127_8395385_3 PFAM Acyl-CoA dehydrogenase type 2 K16047 - 1.14.14.12 4.648e-205 655.0
HKD3_k127_8395385_4 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 568.0
HKD3_k127_8395385_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 561.0
HKD3_k127_8395385_6 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 541.0
HKD3_k127_8395385_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 486.0
HKD3_k127_8395385_8 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 420.0
HKD3_k127_8395385_9 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 397.0
HKD3_k127_8400749_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 5.275e-206 653.0
HKD3_k127_8400749_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 594.0
HKD3_k127_8400749_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 561.0
HKD3_k127_8400749_3 transferase activity, transferring glycosyl groups K16558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 553.0
HKD3_k127_8400749_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377,K16554 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
HKD3_k127_8400749_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000004872 106.0
HKD3_k127_8424474_0 Protein of unknown function - - - 0.0 1357.0
HKD3_k127_8424474_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000001065 236.0
HKD3_k127_8424474_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000007016 161.0
HKD3_k127_8425663_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 440.0
HKD3_k127_8425663_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 402.0
HKD3_k127_8425663_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 288.0
HKD3_k127_8425663_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002003 277.0
HKD3_k127_8425663_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000002785 138.0
HKD3_k127_8425663_6 Protein of unknown function (DUF3299) - - - 0.00001565 51.0
HKD3_k127_8466920_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1210.0
HKD3_k127_8466920_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.047e-199 634.0
HKD3_k127_8466920_2 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 487.0
HKD3_k127_8466920_3 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
HKD3_k127_8466920_4 Transcriptional regulator, Crp Fnr family - - - 0.000000000000000000000000000000000000000000000000007928 188.0
HKD3_k127_84767_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1144.0
HKD3_k127_84767_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 6.917e-199 625.0
HKD3_k127_84767_2 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 447.0
HKD3_k127_84767_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 311.0
HKD3_k127_84767_4 PFAM secretion protein HlyD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 314.0
HKD3_k127_84767_5 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
HKD3_k127_84767_6 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000000000000000000000000000000002518 170.0
HKD3_k127_84767_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000000000000015 146.0
HKD3_k127_84767_8 - - - - 0.0000009813 58.0
HKD3_k127_8497587_0 Belongs to the aldehyde dehydrogenase family - - - 2.498e-279 868.0
HKD3_k127_8497587_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.224e-232 732.0
HKD3_k127_8497587_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
HKD3_k127_8497587_12 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000000000000004854 157.0
HKD3_k127_8497587_13 - - - - 0.0000000000000000000000000000000000000001451 162.0
HKD3_k127_8497587_14 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000009478 77.0
HKD3_k127_8497587_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000959 502.0
HKD3_k127_8497587_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 443.0
HKD3_k127_8497587_4 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 423.0
HKD3_k127_8497587_5 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 319.0
HKD3_k127_8497587_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 327.0
HKD3_k127_8497587_7 Steryl acetyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
HKD3_k127_8497587_8 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
HKD3_k127_8497587_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 253.0
HKD3_k127_8503770_0 Binding-protein-dependent transport system inner membrane component K02011 - - 1.022e-296 926.0
HKD3_k127_8503770_1 PrpF protein - - - 1.762e-202 636.0
HKD3_k127_8503770_2 Transposase - - - 1.275e-196 618.0
HKD3_k127_8503770_3 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
HKD3_k127_8503770_4 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
HKD3_k127_8503770_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005864 260.0
HKD3_k127_8503770_6 Alpha/beta hydrolase family K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000003177 253.0
HKD3_k127_8503770_7 - - - - 0.000000000000000000000000000000000000000001095 158.0
HKD3_k127_8503770_8 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000009513 121.0
HKD3_k127_8505057_0 ABC-type Fe3 transport system permease component K02011 - - 2.082e-300 929.0
HKD3_k127_8505057_1 Bacterial extracellular solute-binding protein K02012 - - 1.611e-198 622.0
HKD3_k127_8505057_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 551.0
HKD3_k127_8505057_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000479 185.0
HKD3_k127_8505963_0 Major Facilitator Superfamily - - - 9.101e-207 663.0
HKD3_k127_8505963_1 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
HKD3_k127_8505963_2 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 369.0
HKD3_k127_8505963_3 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 344.0
HKD3_k127_8530704_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 376.0
HKD3_k127_8530704_2 Belongs to the UPF0337 (CsbD) family - - - 0.000000000000000000000000000000000000001256 150.0
HKD3_k127_854135_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 9.581e-222 691.0
HKD3_k127_854135_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 529.0
HKD3_k127_854135_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 503.0
HKD3_k127_854135_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 - 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 323.0
HKD3_k127_854135_4 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000003779 232.0
HKD3_k127_854135_5 Scavenger mRNA decapping enzyme C-term binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009041 229.0
HKD3_k127_854135_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 - 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000007361 161.0
HKD3_k127_8541907_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 7.003e-318 979.0
HKD3_k127_8541907_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.339e-238 738.0
HKD3_k127_8541907_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 579.0
HKD3_k127_8541907_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 477.0
HKD3_k127_8541907_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 475.0
HKD3_k127_8541907_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 434.0
HKD3_k127_8541907_6 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 341.0
HKD3_k127_8541907_7 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 311.0
HKD3_k127_8541907_8 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 315.0
HKD3_k127_8541907_9 Involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000000000000001085 186.0
HKD3_k127_856183_0 COG0841 Cation multidrug efflux pump - - - 0.0 1761.0
HKD3_k127_856183_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1435.0
HKD3_k127_856183_10 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001756 210.0
HKD3_k127_856183_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122 - 1.17.1.9 1.764e-263 822.0
HKD3_k127_856183_3 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 575.0
HKD3_k127_856183_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 571.0
HKD3_k127_856183_5 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 458.0
HKD3_k127_856183_6 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 442.0
HKD3_k127_856183_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 383.0
HKD3_k127_856183_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 299.0
HKD3_k127_856183_9 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
HKD3_k127_8575511_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 2.85e-258 802.0
HKD3_k127_8575511_1 COG1960 Acyl-CoA dehydrogenases - - - 1.835e-230 715.0
HKD3_k127_8575511_10 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 485.0
HKD3_k127_8575511_11 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 439.0
HKD3_k127_8575511_12 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 376.0
HKD3_k127_8575511_13 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 376.0
HKD3_k127_8575511_14 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 324.0
HKD3_k127_8575511_15 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 292.0
HKD3_k127_8575511_16 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 273.0
HKD3_k127_8575511_17 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002286 246.0
HKD3_k127_8575511_18 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 239.0
HKD3_k127_8575511_19 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000008546 211.0
HKD3_k127_8575511_2 CoA-transferase family III K18702 - 2.8.3.19 1.586e-223 695.0
HKD3_k127_8575511_20 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000002953 180.0
HKD3_k127_8575511_21 - - - - 0.0000000000000000000000000000000000000000000000001807 198.0
HKD3_k127_8575511_3 transport protein CorA K03284 - - 2.14e-204 643.0
HKD3_k127_8575511_4 Belongs to the ALAD family K01698 - 4.2.1.24 5.755e-198 619.0
HKD3_k127_8575511_5 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 601.0
HKD3_k127_8575511_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 576.0
HKD3_k127_8575511_7 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 525.0
HKD3_k127_8575511_8 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 532.0
HKD3_k127_8575511_9 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 487.0
HKD3_k127_8598973_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1320.0
HKD3_k127_8598973_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 2.119e-297 918.0
HKD3_k127_8598973_2 Universal stress protein UspA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
HKD3_k127_8598973_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001568 224.0
HKD3_k127_8598973_4 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000004681 188.0
HKD3_k127_8598973_5 Modulates RecA activity K03565 - - 0.0000000000003798 70.0
HKD3_k127_8609443_0 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 457.0
HKD3_k127_8609443_1 amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 420.0
HKD3_k127_8609443_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 375.0
HKD3_k127_8609443_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 343.0
HKD3_k127_861781_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 426.0
HKD3_k127_861781_1 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 422.0
HKD3_k127_861781_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 415.0
HKD3_k127_861781_3 imidazolonepropionase activity K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 258.0
HKD3_k127_8628168_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 422.0
HKD3_k127_8628168_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 321.0
HKD3_k127_8628168_2 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000006754 109.0
HKD3_k127_8630524_0 Dyp-type peroxidase family K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 355.0
HKD3_k127_8630524_1 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000449 209.0
HKD3_k127_8630524_2 PFAM Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000001053 143.0
HKD3_k127_8647115_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1168.0
HKD3_k127_8647115_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
HKD3_k127_8647115_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 490.0
HKD3_k127_8647115_3 Phosphorylase superfamily K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000002079 231.0
HKD3_k127_8683700_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1688.0
HKD3_k127_8683700_1 Hydantoinase/oxoprolinase - - - 0.0 1174.0
HKD3_k127_8683700_10 - - - - 0.00000000000000000000000000000000000000000001785 175.0
HKD3_k127_8683700_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000009793 48.0
HKD3_k127_8683700_2 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0 1056.0
HKD3_k127_8683700_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 2.56e-247 769.0
HKD3_k127_8683700_4 Receptor family ligand binding region K01999 - - 1.181e-234 729.0
HKD3_k127_8683700_5 Domain of unknown function DUF108 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 444.0
HKD3_k127_8683700_6 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 434.0
HKD3_k127_8683700_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 427.0
HKD3_k127_8683700_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 333.0
HKD3_k127_8683700_9 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003447 235.0
HKD3_k127_8705069_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 410.0
HKD3_k127_8705069_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 313.0
HKD3_k127_8732482_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 522.0
HKD3_k127_8732482_1 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 412.0
HKD3_k127_8732482_2 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003037 278.0
HKD3_k127_8762335_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 6.329e-271 849.0
HKD3_k127_8762335_1 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
HKD3_k127_8762335_2 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 271.0
HKD3_k127_8763383_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1213.0
HKD3_k127_8763383_1 COG0841 Cation multidrug efflux pump K03296 - - 6.594e-270 851.0
HKD3_k127_8763383_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 535.0
HKD3_k127_8763383_3 FAD binding domain - - - 0.000000000000000003267 84.0
HKD3_k127_877067_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 561.0
HKD3_k127_877067_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 417.0
HKD3_k127_877067_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
HKD3_k127_877067_3 transferase activity, transferring glycosyl groups K16558 - - 0.000000000000000000000000000000000000000000000000002673 183.0
HKD3_k127_8786806_0 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 500.0
HKD3_k127_8786806_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 511.0
HKD3_k127_8786806_2 peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 459.0
HKD3_k127_8786806_3 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 411.0
HKD3_k127_8786806_4 Protein of unknown function (DUF962) - - - 0.000000000000000000000000000000000000000000000000005293 186.0
HKD3_k127_8786806_6 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000000000393 115.0
HKD3_k127_8786806_7 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000007369 115.0
HKD3_k127_8786806_8 Protein of unknown function (DUF971) - - - 0.00000000000004604 77.0
HKD3_k127_8792559_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 460.0
HKD3_k127_8792559_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002283 260.0
HKD3_k127_8792559_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000000000000000007814 223.0
HKD3_k127_8792559_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000004458 63.0
HKD3_k127_8795409_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 4.851e-266 835.0
HKD3_k127_8795409_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.609e-214 691.0
HKD3_k127_8795409_2 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 348.0
HKD3_k127_8795409_3 AAA domain, putative AbiEii toxin, Type IV TA system K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 314.0
HKD3_k127_8795409_4 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000001273 234.0
HKD3_k127_8821845_0 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 378.0
HKD3_k127_8821845_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000004257 173.0
HKD3_k127_8821845_2 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000003343 167.0
HKD3_k127_8821845_3 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000005044 61.0
HKD3_k127_8836562_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 514.0
HKD3_k127_8836562_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 461.0
HKD3_k127_8836562_2 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 293.0
HKD3_k127_8836562_3 PHB de-polymerase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000006415 226.0
HKD3_k127_8836562_5 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000003314 125.0
HKD3_k127_8836562_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000006228 54.0
HKD3_k127_8844915_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 0.0 1246.0
HKD3_k127_8844915_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 1.184e-305 968.0
HKD3_k127_8844915_10 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000007329 154.0
HKD3_k127_8844915_11 YCII-related domain K09780 - - 0.00000000000002181 77.0
HKD3_k127_8844915_2 Beta-lactamase - - - 3.065e-230 729.0
HKD3_k127_8844915_3 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 518.0
HKD3_k127_8844915_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 455.0
HKD3_k127_8844915_5 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 429.0
HKD3_k127_8844915_6 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 373.0
HKD3_k127_8844915_7 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001117 250.0
HKD3_k127_8844915_8 Protein conserved in bacteria K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001429 248.0
HKD3_k127_8844915_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000009934 169.0
HKD3_k127_8848331_0 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 440.0
HKD3_k127_8848331_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 334.0
HKD3_k127_8848331_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000009415 190.0
HKD3_k127_8848331_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000143 143.0
HKD3_k127_8850965_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1e-323 991.0
HKD3_k127_8852551_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.967e-264 825.0
HKD3_k127_8852551_1 Amidohydrolase family - - - 7.55e-230 720.0
HKD3_k127_8852551_2 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 6.436e-206 647.0
HKD3_k127_8852551_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 428.0
HKD3_k127_8852551_5 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000009327 235.0
HKD3_k127_8852551_6 - - - - 0.0000000000000000000000000000000000001847 161.0
HKD3_k127_8852551_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000003219 102.0
HKD3_k127_8880357_0 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 321.0
HKD3_k127_8880357_1 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.000000000000000000000000000000000003422 153.0
HKD3_k127_8880357_2 Pilus assembly protein CpaB K02279 - - 0.0000000000000008453 84.0
HKD3_k127_8880357_3 Pilus assembly protein CpaD K02281 - - 0.0006129 51.0
HKD3_k127_8884064_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2444.0
HKD3_k127_8884064_1 Nitrate reductase beta subunit K00371 - 1.7.5.1 0.0 1022.0
HKD3_k127_8884064_2 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 411.0
HKD3_k127_8884064_3 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 383.0
HKD3_k127_8884064_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000002475 160.0
HKD3_k127_889531_0 Carbohydrate-selective porin, OprB family K16080 - - 1.234e-302 936.0
HKD3_k127_889531_1 Carbohydrate-selective porin, OprB family K16080 - - 3.227e-274 858.0
HKD3_k127_889531_2 Uncharacterized ACR, YdiU/UPF0061 family - - - 1.305e-234 734.0
HKD3_k127_889531_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 477.0
HKD3_k127_889531_4 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K02225 - - 0.000000000000000000000000000000000008638 138.0
HKD3_k127_889531_5 - - - - 0.00000000000000000000000000000000002257 138.0
HKD3_k127_8904096_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 380.0
HKD3_k127_8904096_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 376.0
HKD3_k127_8904096_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000001188 168.0
HKD3_k127_8904096_4 cheY-homologous receiver domain - - - 0.0000000000000000002476 93.0
HKD3_k127_8929987_0 Acetolactate synthase K01576,K01652 GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6,4.1.1.7 1.739e-281 879.0
HKD3_k127_8929987_1 - - - - 2.767e-222 696.0
HKD3_k127_8929987_2 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000004194 159.0
HKD3_k127_8929987_3 Luciferase-like monooxygenase - - - 0.00000008038 57.0
HKD3_k127_8933752_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 4.281e-235 734.0
HKD3_k127_8933752_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 525.0
HKD3_k127_8933752_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 252.0
HKD3_k127_8947263_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1341.0
HKD3_k127_8947263_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.883e-268 844.0
HKD3_k127_8947263_2 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 451.0
HKD3_k127_8947263_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 387.0
HKD3_k127_8947263_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 368.0
HKD3_k127_8947263_5 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
HKD3_k127_8947263_6 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 280.0
HKD3_k127_8947263_7 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000004911 258.0
HKD3_k127_8947263_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
HKD3_k127_8947263_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000439 215.0
HKD3_k127_8956797_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 608.0
HKD3_k127_8956797_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 462.0
HKD3_k127_8956797_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 369.0
HKD3_k127_8956797_3 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000008177 232.0
HKD3_k127_8960689_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 488.0
HKD3_k127_8960689_1 isochorismatase, hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
HKD3_k127_8960689_2 Inorganic pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000001406 196.0
HKD3_k127_8990719_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.384e-279 869.0
HKD3_k127_8990719_1 Gamma-glutamyltranspeptidase - - - 5.111e-259 807.0
HKD3_k127_8990719_11 - - - - 0.0000000000000000000003781 98.0
HKD3_k127_8990719_14 PFAM CBS domain containing protein - - - 0.000000000000001391 81.0
HKD3_k127_8990719_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 4.542e-210 655.0
HKD3_k127_8990719_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 5.945e-202 663.0
HKD3_k127_8990719_4 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 589.0
HKD3_k127_8990719_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 541.0
HKD3_k127_8990719_6 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 496.0
HKD3_k127_8990719_7 Chitinase class I K03791 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 318.0
HKD3_k127_8990719_8 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000001257 228.0
HKD3_k127_8990719_9 Conserved hypothetical protein (Lin0512_fam) - - - 0.000000000000000000000000000000000000000000000000002162 183.0
HKD3_k127_8999934_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1777.0
HKD3_k127_8999934_1 DEAD/H associated K03724 - - 0.0 1034.0
HKD3_k127_8999934_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 3.54e-283 880.0
HKD3_k127_8999934_3 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 487.0
HKD3_k127_8999934_4 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 432.0
HKD3_k127_8999934_5 SOS response K14160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 380.0
HKD3_k127_8999934_6 Amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 358.0
HKD3_k127_8999934_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000000008371 222.0
HKD3_k127_9010958_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1199.0
HKD3_k127_9010958_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 1.006e-217 678.0
HKD3_k127_9010958_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 477.0
HKD3_k127_9010958_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000002868 184.0
HKD3_k127_9011730_0 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 4.985e-238 739.0
HKD3_k127_9011730_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 1.81e-219 683.0
HKD3_k127_9011730_2 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 592.0
HKD3_k127_9011730_3 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 380.0
HKD3_k127_9011730_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
HKD3_k127_9011730_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000177 227.0
HKD3_k127_9022746_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 525.0
HKD3_k127_9022746_1 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 523.0
HKD3_k127_9022746_2 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 304.0
HKD3_k127_904105_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0 1056.0
HKD3_k127_904105_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 356.0
HKD3_k127_904105_2 SnoaL-like polyketide cyclase K07255 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
HKD3_k127_904105_3 NHL repeat - - - 0.000000000000000000001428 94.0
HKD3_k127_9096513_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 1.834e-287 888.0
HKD3_k127_9096513_1 5-aminolevulinic acid synthase K00643 - 2.3.1.37 3.656e-226 719.0
HKD3_k127_9096513_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 4.602e-200 624.0
HKD3_k127_9096513_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 602.0
HKD3_k127_9096513_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 532.0
HKD3_k127_9096513_5 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 389.0
HKD3_k127_9096513_6 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000006406 213.0
HKD3_k127_9096513_8 Cytochrome c K08738 - - 0.0000000000000000000000000000001925 137.0
HKD3_k127_9097741_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 3.613e-209 653.0
HKD3_k127_9097741_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 2.46e-204 642.0
HKD3_k127_9097741_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 604.0
HKD3_k127_9097741_3 GntP family permease K03299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 589.0
HKD3_k127_9097741_4 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 503.0
HKD3_k127_9097741_5 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 417.0
HKD3_k127_9097741_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 410.0
HKD3_k127_9098618_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1218.0
HKD3_k127_9098618_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1094.0
HKD3_k127_9098618_10 - - - - 0.000000000000000000000000000000000000000000005477 168.0
HKD3_k127_9098618_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 7.625e-281 869.0
HKD3_k127_9098618_3 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 9.583e-277 856.0
HKD3_k127_9098618_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 5.608e-221 689.0
HKD3_k127_9098618_5 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 556.0
HKD3_k127_9098618_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 556.0
HKD3_k127_9098618_7 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 498.0
HKD3_k127_9098618_8 Domain of unknown function (DUF1849) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 439.0
HKD3_k127_9098618_9 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 372.0
HKD3_k127_9101693_0 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.0 1032.0
HKD3_k127_9101693_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001899 261.0
HKD3_k127_9117465_0 Binding-protein-dependent transport system inner membrane component - - - 0.0 1018.0
HKD3_k127_9117465_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.312e-285 880.0
HKD3_k127_9117465_2 TOBE domain - - - 5.128e-214 667.0
HKD3_k127_9117465_3 Bacterial extracellular solute-binding protein - - - 1.403e-194 610.0
HKD3_k127_9117465_4 L-seryl-tRNA selenium transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 599.0
HKD3_k127_9117465_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 523.0
HKD3_k127_9117465_6 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003218 260.0
HKD3_k127_9117465_7 Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret K03383 - 3.5.2.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000004474 260.0
HKD3_k127_9130787_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0 1266.0
HKD3_k127_9130787_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 545.0
HKD3_k127_9174320_0 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 2.24e-219 682.0
HKD3_k127_9174320_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 468.0
HKD3_k127_9174320_2 Thiamine biosynthesis K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 447.0
HKD3_k127_9174320_3 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 448.0
HKD3_k127_9174320_4 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 372.0
HKD3_k127_9174320_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000472 111.0
HKD3_k127_9174320_6 Protein of unknown function (DUF2630) - - - 0.000000000000000007943 86.0
HKD3_k127_9182718_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 5.854e-202 636.0
HKD3_k127_9182718_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 430.0
HKD3_k127_9182718_2 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 371.0
HKD3_k127_919444_0 cytochrome P-450 - - - 1.785e-218 684.0
HKD3_k127_919444_1 Transport of potassium into the cell - - - 2.464e-194 618.0
HKD3_k127_919444_2 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 546.0
HKD3_k127_919444_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 397.0
HKD3_k127_919444_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 385.0
HKD3_k127_919444_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000000000001438 197.0
HKD3_k127_919444_6 PFAM Usg family protein - - - 0.00000000000000000000000000000000000000000006757 163.0
HKD3_k127_919444_7 Protein of unknown function (DUF3592) - - - 0.0000000000000000000000000000000001921 152.0
HKD3_k127_9201943_0 Rhodanese Homology Domain - - - 9.784e-298 918.0
HKD3_k127_9201943_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 553.0
HKD3_k127_9201943_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 378.0
HKD3_k127_9201943_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000302 147.0
HKD3_k127_9201943_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000001531 109.0
HKD3_k127_9201943_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000004329 68.0
HKD3_k127_9211125_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1400.0
HKD3_k127_9211125_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 340.0
HKD3_k127_9211125_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000002618 74.0
HKD3_k127_9280612_0 Polysaccharide deacetylase - - - 1.051e-195 610.0
HKD3_k127_9280612_1 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 521.0
HKD3_k127_9280612_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 475.0
HKD3_k127_9280612_3 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 459.0
HKD3_k127_9280612_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 324.0
HKD3_k127_9280612_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008214 243.0
HKD3_k127_9299332_0 Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 572.0
HKD3_k127_9299332_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 406.0
HKD3_k127_9299332_10 PFAM Glutathione S-transferase domain - - - 0.0000000000000000000000000000002084 131.0
HKD3_k127_9299332_2 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 334.0
HKD3_k127_9299332_3 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
HKD3_k127_9299332_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
HKD3_k127_9299332_5 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005406 295.0
HKD3_k127_9299332_6 Nad-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000162 271.0
HKD3_k127_9299332_7 FAD binding domain K05898,K13796 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000002645 216.0
HKD3_k127_9299332_8 carbonate dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000001889 203.0
HKD3_k127_9299332_9 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000002725 168.0
HKD3_k127_9305079_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 544.0
HKD3_k127_9305079_1 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
HKD3_k127_9305079_2 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000001999 164.0
HKD3_k127_9306394_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 459.0
HKD3_k127_9306394_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 437.0
HKD3_k127_9306394_2 Belongs to the glycosyl hydrolase 18 family K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 369.0
HKD3_k127_9306394_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 345.0
HKD3_k127_9306394_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006503 263.0
HKD3_k127_9306394_5 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000000000000000001142 235.0
HKD3_k127_9349852_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.045e-289 896.0
HKD3_k127_9349852_1 Protein of unknown function (DUF1800) - - - 4.917e-248 775.0
HKD3_k127_9349852_10 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000167 243.0
HKD3_k127_9349852_12 TspO MBR family protein K05770 - - 0.0000000000000000000000000000000000000001124 166.0
HKD3_k127_9349852_13 - K09712,K14475 - - 0.0000000000000000000000000000000000000001253 154.0
HKD3_k127_9349852_15 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000001618 141.0
HKD3_k127_9349852_16 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00003317 47.0
HKD3_k127_9349852_2 Major Facilitator Superfamily - - - 1.458e-227 722.0
HKD3_k127_9349852_3 Major facilitator superfamily - - - 8.418e-202 643.0
HKD3_k127_9349852_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 479.0
HKD3_k127_9349852_5 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 434.0
HKD3_k127_9349852_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K21395 GO:0003674,GO:0005488,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0030246,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 321.0
HKD3_k127_9349852_7 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 307.0
HKD3_k127_9349852_8 'TIGRFAM RNA polymerase sigma factor, sigma-70 family' K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 292.0
HKD3_k127_9349852_9 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003507 259.0
HKD3_k127_9373795_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 389.0
HKD3_k127_9373795_1 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000001904 119.0
HKD3_k127_9398372_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1673.0
HKD3_k127_9398372_1 serine-type peptidase activity - - - 4.67e-213 670.0
HKD3_k127_9398372_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 428.0
HKD3_k127_9398372_3 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 418.0
HKD3_k127_9398372_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 290.0
HKD3_k127_9398372_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003175 274.0
HKD3_k127_9398372_6 cell division K05803 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 - 0.00000000000000000000000000000000001854 141.0
HKD3_k127_9442471_0 ABC-type Fe3 transport system permease component K02011 - - 4.683e-287 890.0
HKD3_k127_9442471_1 Adenylate and Guanylate cyclase catalytic domain - - - 2.435e-221 725.0
HKD3_k127_9442471_2 ABC-type Fe3 transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004898 274.0
HKD3_k127_9443803_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1287.0
HKD3_k127_9443803_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.0 1175.0
HKD3_k127_9443803_10 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 546.0
HKD3_k127_9443803_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 517.0
HKD3_k127_9443803_12 SbmA/BacA-like family K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 522.0
HKD3_k127_9443803_13 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 444.0
HKD3_k127_9443803_14 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 429.0
HKD3_k127_9443803_15 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 415.0
HKD3_k127_9443803_16 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 387.0
HKD3_k127_9443803_17 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 353.0
HKD3_k127_9443803_18 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 297.0
HKD3_k127_9443803_19 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 299.0
HKD3_k127_9443803_2 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1157.0
HKD3_k127_9443803_20 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
HKD3_k127_9443803_21 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005868 250.0
HKD3_k127_9443803_22 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001697 244.0
HKD3_k127_9443803_23 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002396 250.0
HKD3_k127_9443803_24 FixH - - - 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
HKD3_k127_9443803_25 'PFAM Response regulator receiver - - - 0.0000000000000000000000000000000000000002157 153.0
HKD3_k127_9443803_26 - - - - 0.000000000000000000002495 108.0
HKD3_k127_9443803_29 cytochrome oxidase maturation protein - - - 0.00000000000001164 87.0
HKD3_k127_9443803_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.452e-302 931.0
HKD3_k127_9443803_4 Nitrogen fixation protein fixG - - - 2.95e-262 813.0
HKD3_k127_9443803_5 Haemolysin-type calcium-binding repeat (2 copies) - - - 1.131e-241 757.0
HKD3_k127_9443803_6 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 4.134e-240 759.0
HKD3_k127_9443803_7 Adenylate cyclase - - - 5.946e-219 690.0
HKD3_k127_9443803_8 His Kinase A (phosphoacceptor) domain - - - 1.06e-201 650.0
HKD3_k127_9443803_9 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 558.0
HKD3_k127_9456681_0 Peptidase dimerisation domain - - - 5.087e-217 676.0
HKD3_k127_9456681_1 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 1.592e-206 647.0
HKD3_k127_9530992_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 404.0
HKD3_k127_9530992_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 385.0
HKD3_k127_9530992_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 366.0
HKD3_k127_9530992_3 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000356 229.0
HKD3_k127_9530992_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000089 163.0
HKD3_k127_9530992_5 Flavoprotein involved in K transport - - - 0.00000000000000000000000000000000000000004116 157.0
HKD3_k127_9530992_6 SnoaL-like domain - - - 0.000000000000000000000000002316 115.0
HKD3_k127_954087_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 605.0
HKD3_k127_954087_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 593.0
HKD3_k127_954087_10 - - - - 0.000000000000000000000327 99.0
HKD3_k127_954087_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 503.0
HKD3_k127_954087_3 transcriptional regulator, MerR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 313.0
HKD3_k127_954087_4 Uncharacterized ACR, COG1399 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008286 270.0
HKD3_k127_954087_5 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002626 263.0
HKD3_k127_954087_6 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000176 260.0
HKD3_k127_954087_7 COG2913 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HKD3_k127_954087_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000008353 150.0
HKD3_k127_954087_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000000000102 108.0
HKD3_k127_9588915_0 Luciferase-like monooxygenase - - - 8.924e-194 608.0
HKD3_k127_9588915_1 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 475.0
HKD3_k127_9588915_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 472.0
HKD3_k127_9588915_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 477.0
HKD3_k127_9588915_4 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008838 269.0
HKD3_k127_9588915_5 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000001406 218.0
HKD3_k127_9588915_6 - - - - 0.00000000000000000000000000191 116.0
HKD3_k127_9600770_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1870.0
HKD3_k127_9600770_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 7.123e-224 697.0
HKD3_k127_9600770_2 AFG1-like ATPase K06916 - - 1.819e-206 646.0
HKD3_k127_9600770_3 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 597.0
HKD3_k127_9600770_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 531.0
HKD3_k127_9600770_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 488.0
HKD3_k127_9600770_6 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 468.0
HKD3_k127_9600770_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 456.0
HKD3_k127_9600770_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 420.0
HKD3_k127_9600770_9 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 356.0
HKD3_k127_9616249_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 1.317e-201 635.0
HKD3_k127_9616249_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 524.0
HKD3_k127_9616249_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 493.0
HKD3_k127_9616249_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 345.0
HKD3_k127_9616249_4 belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003304 254.0
HKD3_k127_9616249_6 methyltransferase - - - 0.0008566 51.0
HKD3_k127_9626731_0 Luciferase-like monooxygenase K09018 - 1.14.99.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 542.0
HKD3_k127_9626731_1 Luciferase-like monooxygenase K09018 - 1.14.99.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 529.0
HKD3_k127_9626731_10 PFAM FAD linked oxidase domain protein - - - 0.0000000000607 66.0
HKD3_k127_9626731_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 474.0
HKD3_k127_9626731_3 Acetamidase/Formamidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 476.0
HKD3_k127_9626731_4 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 334.0
HKD3_k127_9626731_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000002283 213.0
HKD3_k127_9626731_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000004806 191.0
HKD3_k127_9626731_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000003829 149.0
HKD3_k127_9626731_9 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000001002 124.0
HKD3_k127_974828_0 Chromate transporter K07240 - - 9.098e-212 666.0
HKD3_k127_974828_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 464.0
HKD3_k127_974828_10 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000002461 130.0
HKD3_k127_974828_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 403.0
HKD3_k127_974828_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 349.0
HKD3_k127_974828_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 314.0
HKD3_k127_974828_5 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 289.0
HKD3_k127_974828_6 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 289.0
HKD3_k127_974828_7 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001363 281.0
HKD3_k127_974828_8 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003817 244.0
HKD3_k127_974828_9 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000004796 219.0
HKD3_k127_977357_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 598.0
HKD3_k127_977357_1 Proline racemase K12658 - 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 541.0
HKD3_k127_977357_2 Belongs to the DapA family K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 442.0
HKD3_k127_977357_3 Shikimate kinase - - - 0.00000000000000000000000000000000000000000003224 168.0
HKD3_k127_977357_4 CoA-transferase family III - - - 0.000000000000000000000009854 100.0