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Overview

ID MAG01847
Name HKD3_bin.3
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus RBG-13-68-16
Species
Assembly information
Completeness (%) 85.63
Contamination (%) 0.4
GC content (%) 68.0
N50 (bp) 12,073
Genome size (bp) 2,635,647

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2257

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1013551_0 PFAM Aldehyde dehydrogenase K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 1.488e-237 745.0
HKD3_k127_1013551_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.58e-203 651.0
HKD3_k127_1013551_10 ATPase activity K01990,K13926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 264.0
HKD3_k127_1013551_11 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002445 267.0
HKD3_k127_1013551_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
HKD3_k127_1013551_13 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000001059 209.0
HKD3_k127_1013551_14 - - - - 0.00000000000000000000000000000000000002225 152.0
HKD3_k127_1013551_15 4Fe-4S binding domain - - - 0.000000000000000000000000000003923 121.0
HKD3_k127_1013551_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000005462 127.0
HKD3_k127_1013551_17 peptidyl-tyrosine sulfation - - - 0.00000000000000000000001208 117.0
HKD3_k127_1013551_18 PFAM Outer membrane efflux protein K03287 - - 0.0000000000003629 83.0
HKD3_k127_1013551_19 membrane protein domain - - - 0.000000000006616 78.0
HKD3_k127_1013551_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 430.0
HKD3_k127_1013551_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
HKD3_k127_1013551_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 335.0
HKD3_k127_1013551_5 ABC transporter, (ATP-binding protein) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 312.0
HKD3_k127_1013551_6 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 308.0
HKD3_k127_1013551_7 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 314.0
HKD3_k127_1013551_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HKD3_k127_1013551_9 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009206 278.0
HKD3_k127_115506_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 587.0
HKD3_k127_115506_2 - - - - 0.00000000000004963 86.0
HKD3_k127_115506_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0002807 54.0
HKD3_k127_1223114_0 PFAM RNA polymerase sigma factor 54, interaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 541.0
HKD3_k127_1223114_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000006667 63.0
HKD3_k127_1233400_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 550.0
HKD3_k127_1233400_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 460.0
HKD3_k127_1233400_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 441.0
HKD3_k127_1233400_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 392.0
HKD3_k127_1233400_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001525 287.0
HKD3_k127_124657_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 475.0
HKD3_k127_124657_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 409.0
HKD3_k127_124657_2 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000002791 132.0
HKD3_k127_1250165_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 375.0
HKD3_k127_1250165_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000003692 190.0
HKD3_k127_1250165_3 Protein of unknown function (DUF1232) - - - 0.000000000000000007766 90.0
HKD3_k127_1263387_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 434.0
HKD3_k127_1271118_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 293.0
HKD3_k127_1271118_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000284 106.0
HKD3_k127_1271118_2 Amidohydrolase family - - - 0.0000000000000009024 81.0
HKD3_k127_127796_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 503.0
HKD3_k127_127796_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 415.0
HKD3_k127_127796_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 395.0
HKD3_k127_127796_3 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 348.0
HKD3_k127_127796_4 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 321.0
HKD3_k127_127796_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002954 246.0
HKD3_k127_127796_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000003346 175.0
HKD3_k127_127796_7 HD domain - - - 0.00000000000000000000000000000000000000002094 173.0
HKD3_k127_127796_8 response to abiotic stimulus - - - 0.0000000000000000000000000000000000001285 160.0
HKD3_k127_127796_9 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000003608 76.0
HKD3_k127_1279009_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 488.0
HKD3_k127_1279009_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 428.0
HKD3_k127_1279009_2 oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000002 151.0
HKD3_k127_1279009_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000004591 95.0
HKD3_k127_1282333_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
HKD3_k127_1282333_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000007197 172.0
HKD3_k127_1282333_2 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000006127 127.0
HKD3_k127_1282333_3 - - - - 0.000000000000001772 83.0
HKD3_k127_1306837_0 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 333.0
HKD3_k127_1306837_2 Tetratricopeptide repeat - - - 0.00055 46.0
HKD3_k127_1308925_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.342e-217 683.0
HKD3_k127_1308925_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 586.0
HKD3_k127_1325266_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 3.86e-231 731.0
HKD3_k127_1325266_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 3.427e-211 672.0
HKD3_k127_1325266_10 - - - - 0.000000003321 59.0
HKD3_k127_1325266_11 Psort location CytoplasmicMembrane, score - - - 0.000007325 57.0
HKD3_k127_1325266_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 425.0
HKD3_k127_1325266_3 Zinc-binding dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 328.0
HKD3_k127_1325266_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004786 260.0
HKD3_k127_1325266_5 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
HKD3_k127_1325266_6 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000003283 237.0
HKD3_k127_1325266_7 epimerase - - - 0.0000000000000000000000000000000000000000000003376 172.0
HKD3_k127_1325266_8 Protein tyrosine kinase - - - 0.00000000000000000000000000003611 134.0
HKD3_k127_1325266_9 Intracellular proteinase inhibitor - - - 0.00000000000006438 84.0
HKD3_k127_1353700_0 Protein kinase domain K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 451.0
HKD3_k127_1353700_1 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000007836 221.0
HKD3_k127_1353700_2 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000006302 176.0
HKD3_k127_1353700_3 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000004389 177.0
HKD3_k127_1353700_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000436 151.0
HKD3_k127_1368733_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 422.0
HKD3_k127_1368733_1 TIGRFAM phage plasmid-related protein TIGR03299 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 363.0
HKD3_k127_1368733_10 Sigma-54 interaction domain K07713,K07714 - - 0.000000000000000000000000007672 120.0
HKD3_k127_1368733_11 Histidine kinase - - - 0.0000000000004189 71.0
HKD3_k127_1368733_12 Domain of unknown function (DUF4198) - - - 0.000000000002923 78.0
HKD3_k127_1368733_2 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 304.0
HKD3_k127_1368733_3 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
HKD3_k127_1368733_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000001012 226.0
HKD3_k127_1368733_5 DNA recombination - - - 0.000000000000000000000000000000000000000000000000000000001273 209.0
HKD3_k127_1368733_6 Virulence-associated protein E - - - 0.00000000000000000000000000000000000000000000000000001155 212.0
HKD3_k127_1368733_7 response to copper ion K16915 - - 0.000000000000000000000000000000000000002692 151.0
HKD3_k127_1368733_8 Bifunctional DNA primase/polymerase, N-terminal - - - 0.00000000000000000000000000006595 130.0
HKD3_k127_1368733_9 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000007482 135.0
HKD3_k127_1370441_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 341.0
HKD3_k127_1370441_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000001003 239.0
HKD3_k127_1370441_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000004849 111.0
HKD3_k127_137143_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 458.0
HKD3_k127_137143_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 421.0
HKD3_k127_137143_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 335.0
HKD3_k127_137143_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000001234 163.0
HKD3_k127_1390894_0 Involved in the tonB-independent uptake of proteins K01256,K03641 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 456.0
HKD3_k127_140592_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 419.0
HKD3_k127_140592_1 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000001338 206.0
HKD3_k127_140592_2 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000002101 195.0
HKD3_k127_1411019_0 - - - - 0.00000000000000000000000000000000000000000000001897 189.0
HKD3_k127_1411019_1 kinase activity K02850 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000009194 83.0
HKD3_k127_1411019_2 - - - - 0.00000000001078 73.0
HKD3_k127_1411019_3 Polymer-forming cytoskeletal - - - 0.00004721 48.0
HKD3_k127_1418387_0 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000001665 214.0
HKD3_k127_1418387_1 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000001568 196.0
HKD3_k127_1418387_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000002762 114.0
HKD3_k127_1418936_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 334.0
HKD3_k127_1418936_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000001236 261.0
HKD3_k127_1418936_2 Ras family - - - 0.000000000000000000000000000000000000000000000000000000000001929 234.0
HKD3_k127_1418936_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000007447 198.0
HKD3_k127_1418936_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000002628 183.0
HKD3_k127_1418936_5 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000005091 136.0
HKD3_k127_1418936_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000002026 125.0
HKD3_k127_1418936_7 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000001003 132.0
HKD3_k127_1418936_8 Histidine kinase - - - 0.0000000000000007341 90.0
HKD3_k127_1418936_9 general secretion pathway protein K08084,K08085 - - 0.00001053 55.0
HKD3_k127_1437625_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 543.0
HKD3_k127_1437625_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001649 142.0
HKD3_k127_1437625_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000004385 105.0
HKD3_k127_1437625_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000002401 80.0
HKD3_k127_1437625_4 Roadblock/LC7 domain - - - 0.00000002186 62.0
HKD3_k127_143906_0 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 493.0
HKD3_k127_143906_1 PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000009666 224.0
HKD3_k127_1443157_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 422.0
HKD3_k127_1443157_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 310.0
HKD3_k127_1443157_10 Neuraminyllactose-binding hemagglutinin precursor (NLBH) K15846 - - 0.0000000005242 70.0
HKD3_k127_1443157_11 helix_turn_helix, Lux Regulon - - - 0.000004292 59.0
HKD3_k127_1443157_12 Amino acid permease - - - 0.0007619 44.0
HKD3_k127_1443157_2 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 293.0
HKD3_k127_1443157_3 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000001727 186.0
HKD3_k127_1443157_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000007883 166.0
HKD3_k127_1443157_5 OsmC-like protein K07397 - - 0.000000000000000000000000001513 117.0
HKD3_k127_1443157_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000003375 122.0
HKD3_k127_1443157_7 Peptidase family M23 K21471 - - 0.00000000000000000001981 105.0
HKD3_k127_1443157_8 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000002322 94.0
HKD3_k127_1443157_9 Beta-lactamase - - - 0.00000000003725 65.0
HKD3_k127_1454643_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 520.0
HKD3_k127_1454643_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 514.0
HKD3_k127_1454643_10 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000002438 195.0
HKD3_k127_1454643_11 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000658 187.0
HKD3_k127_1454643_12 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000269 178.0
HKD3_k127_1454643_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.0000000000000000000000000000000003432 154.0
HKD3_k127_1454643_14 - - - - 0.0000000000000000000000000000000006392 144.0
HKD3_k127_1454643_15 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000003305 133.0
HKD3_k127_1454643_16 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000001606 121.0
HKD3_k127_1454643_17 ATPase or kinase K06925 - - 0.0000000000000000003233 102.0
HKD3_k127_1454643_19 PFAM Forkhead-associated protein - - - 0.0000000004742 66.0
HKD3_k127_1454643_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 494.0
HKD3_k127_1454643_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 484.0
HKD3_k127_1454643_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 398.0
HKD3_k127_1454643_5 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 353.0
HKD3_k127_1454643_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 325.0
HKD3_k127_1454643_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
HKD3_k127_1454643_8 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000002644 250.0
HKD3_k127_1454643_9 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.00000000000000000000000000000000000000000000000000000000000512 226.0
HKD3_k127_1499624_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 434.0
HKD3_k127_1499624_1 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000004504 229.0
HKD3_k127_1499624_2 - - - - 0.00000000000000000000000000000000000000000000000000001131 193.0
HKD3_k127_1499624_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000007517 197.0
HKD3_k127_1499624_4 Binds the 23S rRNA K02909 - - 0.000000000000000000000000105 108.0
HKD3_k127_1541814_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 483.0
HKD3_k127_1541814_1 signal peptide processing K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
HKD3_k127_1541814_2 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000003474 179.0
HKD3_k127_1541814_3 Putative adhesin - - - 0.0000000000000000000000003195 113.0
HKD3_k127_1541814_4 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000001076 109.0
HKD3_k127_1541814_5 Domain of unknown function (DUF4349) - - - 0.000002529 59.0
HKD3_k127_1544297_0 Aminotransferase, class I K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 521.0
HKD3_k127_1544297_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000002284 102.0
HKD3_k127_155987_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
HKD3_k127_155987_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 398.0
HKD3_k127_155987_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000003838 85.0
HKD3_k127_155987_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000003756 71.0
HKD3_k127_1600119_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 598.0
HKD3_k127_1600119_1 Proton-conducting membrane transporter K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000261 239.0
HKD3_k127_1600119_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.0000000003699 68.0
HKD3_k127_1671634_0 AAA domain (Cdc48 subfamily) K03544 - - 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
HKD3_k127_1671634_1 Ankyrin repeats (many copies) K06867,K21440 - - 0.000000000000000000002995 106.0
HKD3_k127_1671634_2 DEAD/H associated K03724 - - 0.00000000000136 70.0
HKD3_k127_1684925_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 554.0
HKD3_k127_1684925_1 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 423.0
HKD3_k127_1684925_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000002335 229.0
HKD3_k127_1684925_3 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000001861 181.0
HKD3_k127_1730306_0 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 429.0
HKD3_k127_1730306_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007138 279.0
HKD3_k127_1730306_2 spore germination - - - 0.00000000000000000000000000000000000000000000000000005662 198.0
HKD3_k127_1730306_5 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0002224 46.0
HKD3_k127_1788327_0 Heat shock 70 kDa protein K04043 - - 6.737e-289 899.0
HKD3_k127_1788327_1 symporter activity K03307,K11928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 512.0
HKD3_k127_1788327_10 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000000000000946 132.0
HKD3_k127_1788327_11 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000003531 131.0
HKD3_k127_1788327_12 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000003084 125.0
HKD3_k127_1788327_13 NUDIX domain K03574 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000008983 113.0
HKD3_k127_1788327_14 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000116 103.0
HKD3_k127_1788327_15 COG3209 Rhs family protein - - - 0.0000000000000000008358 101.0
HKD3_k127_1788327_16 - - - - 0.000000000000000005508 91.0
HKD3_k127_1788327_17 Tetratricopeptide repeat - - - 0.0000000000001365 84.0
HKD3_k127_1788327_18 Hsp20/alpha crystallin family K13993 - - 0.000000000000749 76.0
HKD3_k127_1788327_19 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000002172 80.0
HKD3_k127_1788327_2 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 405.0
HKD3_k127_1788327_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000008491 72.0
HKD3_k127_1788327_21 Domain of unknown function (DUF1844) - - - 0.00001808 52.0
HKD3_k127_1788327_3 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006787 278.0
HKD3_k127_1788327_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 258.0
HKD3_k127_1788327_5 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000178 259.0
HKD3_k127_1788327_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
HKD3_k127_1788327_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000003027 227.0
HKD3_k127_1788327_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000001984 195.0
HKD3_k127_1788327_9 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000007205 182.0
HKD3_k127_1924521_0 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 333.0
HKD3_k127_1924521_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003707 291.0
HKD3_k127_1924521_2 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000005656 113.0
HKD3_k127_196908_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000003499 267.0
HKD3_k127_196908_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000001145 74.0
HKD3_k127_1980217_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.26e-287 899.0
HKD3_k127_1980217_1 GTP-binding protein TypA K06207 - - 1.796e-257 807.0
HKD3_k127_1980217_10 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 370.0
HKD3_k127_1980217_11 abc transporter atp-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 360.0
HKD3_k127_1980217_12 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
HKD3_k127_1980217_13 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 306.0
HKD3_k127_1980217_14 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003494 286.0
HKD3_k127_1980217_15 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006735 285.0
HKD3_k127_1980217_16 PFAM Uracil DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000001249 249.0
HKD3_k127_1980217_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000008218 171.0
HKD3_k127_1980217_18 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000003601 164.0
HKD3_k127_1980217_19 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000001099 151.0
HKD3_k127_1980217_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 2.454e-216 688.0
HKD3_k127_1980217_20 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000001971 160.0
HKD3_k127_1980217_21 Ubiquinone biosynthesis protein UbiA K02548 - 2.5.1.74 0.0000000000000000000000000000005633 138.0
HKD3_k127_1980217_22 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000573 124.0
HKD3_k127_1980217_23 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001097 126.0
HKD3_k127_1980217_24 Tetratricopeptide repeat - - - 0.0000000000000000000000003117 119.0
HKD3_k127_1980217_25 Thioesterase K01075 - 3.1.2.23 0.0000000000000000000000005642 113.0
HKD3_k127_1980217_26 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000003203 76.0
HKD3_k127_1980217_27 DNA polymerase III subunit chi K02339 - 2.7.7.7 0.000000002956 64.0
HKD3_k127_1980217_28 Cyclic nucleotide-monophosphate binding domain - - - 0.00000009175 65.0
HKD3_k127_1980217_29 Outer membrane protein (OmpH-like) K06142 - - 0.0000003791 59.0
HKD3_k127_1980217_3 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 537.0
HKD3_k127_1980217_30 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000004792 57.0
HKD3_k127_1980217_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
HKD3_k127_1980217_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 464.0
HKD3_k127_1980217_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 404.0
HKD3_k127_1980217_8 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 392.0
HKD3_k127_1980217_9 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 373.0
HKD3_k127_1981820_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 4.934e-230 729.0
HKD3_k127_1981820_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 294.0
HKD3_k127_1981820_2 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD3_k127_1981820_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
HKD3_k127_1981820_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001496 247.0
HKD3_k127_214386_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 591.0
HKD3_k127_214386_1 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 435.0
HKD3_k127_214386_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 424.0
HKD3_k127_214386_3 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 339.0
HKD3_k127_214386_4 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 256.0
HKD3_k127_214386_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000005041 200.0
HKD3_k127_214386_6 GYD domain - - - 0.000000000000000000000000000002243 126.0
HKD3_k127_214386_7 amidohydrolase - - - 0.000000003717 58.0
HKD3_k127_214386_9 Calcineurin-like phosphoesterase - - - 0.0000005391 61.0
HKD3_k127_2239378_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 336.0
HKD3_k127_2239378_1 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 304.0
HKD3_k127_2239378_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000003201 147.0
HKD3_k127_2239378_3 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000009153 118.0
HKD3_k127_2239378_4 - - - - 0.00000000000000000002356 100.0
HKD3_k127_225718_0 ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 350.0
HKD3_k127_225718_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000002111 108.0
HKD3_k127_230153_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1148.0
HKD3_k127_230153_1 Response regulator, receiver K01007 - 2.7.9.2 2.099e-245 791.0
HKD3_k127_230153_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.685e-210 663.0
HKD3_k127_230153_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 3.205e-194 624.0
HKD3_k127_230153_4 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 558.0
HKD3_k127_230153_5 secondary active sulfate transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 538.0
HKD3_k127_230153_6 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 310.0
HKD3_k127_230153_7 B3/4 domain - - - 0.000000000000000001632 97.0
HKD3_k127_230153_8 - - - - 0.00000000002191 70.0
HKD3_k127_2415421_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 524.0
HKD3_k127_2415421_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000554 278.0
HKD3_k127_2415421_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000002988 211.0
HKD3_k127_2415421_3 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000003273 152.0
HKD3_k127_2415421_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000005874 117.0
HKD3_k127_2427070_0 COGs COG3533 conserved K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 385.0
HKD3_k127_2427070_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 346.0
HKD3_k127_2427070_2 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000003834 149.0
HKD3_k127_2446160_0 tagaturonate epimerase - - - 2.063e-207 663.0
HKD3_k127_2446160_1 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 583.0
HKD3_k127_2446160_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 348.0
HKD3_k127_2463851_0 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 376.0
HKD3_k127_2463851_1 transporter, DctM subunit K11690 - - 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
HKD3_k127_2463851_2 TRAP transporter T-component - - - 0.00000000000232 67.0
HKD3_k127_2466145_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000003982 241.0
HKD3_k127_2466145_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0000000000000000000000000000000000000000000002529 168.0
HKD3_k127_2466912_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 391.0
HKD3_k127_2466912_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
HKD3_k127_2466912_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000005073 185.0
HKD3_k127_2466912_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000849 128.0
HKD3_k127_2466912_4 - - - - 0.0000000000003049 72.0
HKD3_k127_2466912_5 Putative regulatory protein - - - 0.0000001856 60.0
HKD3_k127_2466912_6 GGDEF domain - - - 0.0000005909 54.0
HKD3_k127_2470277_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.793e-275 870.0
HKD3_k127_2470277_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.306e-204 651.0
HKD3_k127_2470277_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005954 257.0
HKD3_k127_2470277_11 Alpha beta - - - 0.0000000000000000000000000000000000000000000000000000007888 203.0
HKD3_k127_2470277_12 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000001261 192.0
HKD3_k127_2470277_13 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000002464 165.0
HKD3_k127_2470277_14 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000388 153.0
HKD3_k127_2470277_15 PHP domain protein K02347 - - 0.00000000000000000000000000000001255 131.0
HKD3_k127_2470277_16 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000005217 127.0
HKD3_k127_2470277_17 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000002544 96.0
HKD3_k127_2470277_18 - - - - 0.00000000000000003797 91.0
HKD3_k127_2470277_19 Redox-active disulfide protein - - - 0.00000000000005652 83.0
HKD3_k127_2470277_2 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 472.0
HKD3_k127_2470277_20 - - - - 0.0000000001394 66.0
HKD3_k127_2470277_21 - - - - 0.0000000002407 64.0
HKD3_k127_2470277_22 Pilus assembly protein PilW K02656 - - 0.000001752 59.0
HKD3_k127_2470277_23 Roadblock/LC7 domain - - - 0.00002192 53.0
HKD3_k127_2470277_3 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 458.0
HKD3_k127_2470277_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 322.0
HKD3_k127_2470277_5 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 324.0
HKD3_k127_2470277_6 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 305.0
HKD3_k127_2470277_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 290.0
HKD3_k127_2470277_8 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000006502 262.0
HKD3_k127_2470277_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005825 259.0
HKD3_k127_247884_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1672.0
HKD3_k127_247884_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1438.0
HKD3_k127_247884_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002299 118.0
HKD3_k127_247884_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001773 82.0
HKD3_k127_247884_12 Ribosomal protein L33 K02913 - - 0.00000000000002891 75.0
HKD3_k127_247884_13 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000003468 55.0
HKD3_k127_247884_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 5.535e-306 952.0
HKD3_k127_247884_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.788e-203 638.0
HKD3_k127_247884_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 305.0
HKD3_k127_247884_5 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000001106 231.0
HKD3_k127_247884_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
HKD3_k127_247884_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD3_k127_247884_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
HKD3_k127_247884_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000003561 149.0
HKD3_k127_2479275_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 8.513e-259 810.0
HKD3_k127_2479275_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000009827 217.0
HKD3_k127_2485809_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 404.0
HKD3_k127_2485809_1 ABC transporter K02013 - 3.6.3.34 0.0000006176 57.0
HKD3_k127_2492_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000005513 217.0
HKD3_k127_2492_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001271 219.0
HKD3_k127_2492_2 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000009226 166.0
HKD3_k127_2492_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000003245 112.0
HKD3_k127_2492_4 - - - - 0.000000000007569 77.0
HKD3_k127_2494414_0 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000009406 146.0
HKD3_k127_2494414_2 Transposase IS200 like - - - 0.00000000000000000000000000002037 130.0
HKD3_k127_2494414_3 PAP2 superfamily - - - 0.0000000000000000000372 100.0
HKD3_k127_2495539_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 496.0
HKD3_k127_2495539_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 426.0
HKD3_k127_2495539_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 420.0
HKD3_k127_2495539_3 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006374 267.0
HKD3_k127_2495539_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000001601 229.0
HKD3_k127_2495539_5 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000003909 172.0
HKD3_k127_2495539_6 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000004272 168.0
HKD3_k127_2495539_7 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000004897 139.0
HKD3_k127_2495539_8 PFAM FecR protein - - - 0.0000000000000000006436 100.0
HKD3_k127_2495539_9 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000002864 81.0
HKD3_k127_2505189_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
HKD3_k127_2505189_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 375.0
HKD3_k127_2505189_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000001702 156.0
HKD3_k127_2505189_11 toxin-antitoxin pair type II binding K08591,K19159 GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 2.3.1.15 0.000000000006945 70.0
HKD3_k127_2505189_12 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000105 50.0
HKD3_k127_2505189_2 PHP domain protein K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
HKD3_k127_2505189_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009655 273.0
HKD3_k127_2505189_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003144 278.0
HKD3_k127_2505189_5 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HKD3_k127_2505189_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000001562 228.0
HKD3_k127_2505189_7 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000004744 188.0
HKD3_k127_2505189_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000005889 181.0
HKD3_k127_2505189_9 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000001246 172.0
HKD3_k127_2513458_0 AcrB/AcrD/AcrF family K03296 - - 2.057e-304 960.0
HKD3_k127_2513458_1 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.913e-212 685.0
HKD3_k127_2513458_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 418.0
HKD3_k127_2513458_3 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003335 228.0
HKD3_k127_2513458_4 - - - - 0.000000000000002453 82.0
HKD3_k127_2513458_5 Acetyltransferase (GNAT) domain - - - 0.000000000000004783 87.0
HKD3_k127_2554344_0 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 401.0
HKD3_k127_2554344_1 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 333.0
HKD3_k127_2554344_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000007389 261.0
HKD3_k127_2554344_3 Serine threonine protein kinase K07282,K12132,K15539 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003387 235.0
HKD3_k127_2559470_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000002341 125.0
HKD3_k127_2559470_1 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.000000000000000006768 98.0
HKD3_k127_2559470_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000186 76.0
HKD3_k127_2559470_3 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.00002224 55.0
HKD3_k127_2594802_0 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
HKD3_k127_2594802_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 384.0
HKD3_k127_2594802_2 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000002106 233.0
HKD3_k127_2594802_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000008969 138.0
HKD3_k127_2595732_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.448e-293 927.0
HKD3_k127_2595732_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 495.0
HKD3_k127_2595732_10 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000003594 174.0
HKD3_k127_2595732_11 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000006046 172.0
HKD3_k127_2595732_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000001169 124.0
HKD3_k127_2595732_13 cheY-homologous receiver domain - - - 0.000000000000000000000284 102.0
HKD3_k127_2595732_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000002296 93.0
HKD3_k127_2595732_15 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000009337 94.0
HKD3_k127_2595732_16 regulatory protein, arsR K03892 - - 0.00000000000008852 78.0
HKD3_k127_2595732_17 - - - - 0.0000000003083 68.0
HKD3_k127_2595732_18 SH3 type 3 domain protein K01447 - 3.5.1.28 0.000000000839 68.0
HKD3_k127_2595732_2 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 476.0
HKD3_k127_2595732_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 387.0
HKD3_k127_2595732_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 300.0
HKD3_k127_2595732_5 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002161 256.0
HKD3_k127_2595732_6 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
HKD3_k127_2595732_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000112 233.0
HKD3_k127_2595732_8 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001213 227.0
HKD3_k127_2595732_9 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000004709 206.0
HKD3_k127_2599566_0 Na H antiporter K03315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 401.0
HKD3_k127_2599566_1 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 381.0
HKD3_k127_2599566_2 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000129 251.0
HKD3_k127_2599566_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000001699 226.0
HKD3_k127_2599566_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.0000000000000000000000000000000000000000000001917 171.0
HKD3_k127_2599566_5 Histidine kinase K11383 - 2.7.13.3 0.00000000000000000000000000000000000000006365 169.0
HKD3_k127_2599566_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.00000000000000000000000000000000000002884 151.0
HKD3_k127_2599566_7 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000002106 126.0
HKD3_k127_2599650_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.432e-199 627.0
HKD3_k127_2599650_1 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 459.0
HKD3_k127_2599650_10 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 330.0
HKD3_k127_2599650_11 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002887 287.0
HKD3_k127_2599650_12 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 271.0
HKD3_k127_2599650_13 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000002735 239.0
HKD3_k127_2599650_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000001258 229.0
HKD3_k127_2599650_15 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000004219 179.0
HKD3_k127_2599650_16 Signal peptidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000002496 167.0
HKD3_k127_2599650_17 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000004617 164.0
HKD3_k127_2599650_18 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000004944 165.0
HKD3_k127_2599650_19 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000002794 147.0
HKD3_k127_2599650_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 452.0
HKD3_k127_2599650_20 amidohydrolase - - - 0.000000000000000000000000000000000002379 158.0
HKD3_k127_2599650_21 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000001265 139.0
HKD3_k127_2599650_22 FMN binding - - - 0.0000000000000000000000000002865 121.0
HKD3_k127_2599650_23 Hfq protein - - - 0.000000000000000000000000007205 116.0
HKD3_k127_2599650_24 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000001211 106.0
HKD3_k127_2599650_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004708 70.0
HKD3_k127_2599650_27 Methionine biosynthesis protein MetW - - - 0.000001348 59.0
HKD3_k127_2599650_28 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000857 59.0
HKD3_k127_2599650_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 421.0
HKD3_k127_2599650_4 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 406.0
HKD3_k127_2599650_5 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 361.0
HKD3_k127_2599650_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 352.0
HKD3_k127_2599650_7 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 339.0
HKD3_k127_2599650_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
HKD3_k127_2599650_9 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 335.0
HKD3_k127_2619030_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 339.0
HKD3_k127_2619030_1 Glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000002515 51.0
HKD3_k127_2620099_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 602.0
HKD3_k127_2620099_1 Peptidase dimerisation domain K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 495.0
HKD3_k127_2620099_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000001105 224.0
HKD3_k127_2620099_11 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000009588 186.0
HKD3_k127_2620099_12 DoxX K15977 - - 0.00000000000000000000000000000000000000000000003423 174.0
HKD3_k127_2620099_13 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000001869 181.0
HKD3_k127_2620099_14 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000709 156.0
HKD3_k127_2620099_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000032 151.0
HKD3_k127_2620099_16 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000001659 145.0
HKD3_k127_2620099_17 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000004331 139.0
HKD3_k127_2620099_18 Protein of unknown function DUF58 - - - 0.00000000000000000000000001507 122.0
HKD3_k127_2620099_19 PAP2 superfamily - - - 0.00000000000000000000000007451 119.0
HKD3_k127_2620099_2 CBS domain containing protein K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 505.0
HKD3_k127_2620099_20 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000001005 106.0
HKD3_k127_2620099_21 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000002194 96.0
HKD3_k127_2620099_22 Pilus assembly protein, PilP - - - 0.00000000000000842 79.0
HKD3_k127_2620099_23 Bacterial SH3 domain K01876 - 6.1.1.12 0.00006317 55.0
HKD3_k127_2620099_24 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00038 53.0
HKD3_k127_2620099_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
HKD3_k127_2620099_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 327.0
HKD3_k127_2620099_5 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 335.0
HKD3_k127_2620099_6 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 316.0
HKD3_k127_2620099_7 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 301.0
HKD3_k127_2620099_8 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 297.0
HKD3_k127_2620099_9 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005564 259.0
HKD3_k127_2627861_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004325 280.0
HKD3_k127_2627861_1 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
HKD3_k127_2627861_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000002926 111.0
HKD3_k127_2627861_3 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.0000000000000001354 83.0
HKD3_k127_2627861_4 FR47-like protein - - - 0.0002117 51.0
HKD3_k127_2634694_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 446.0
HKD3_k127_2634694_1 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 435.0
HKD3_k127_2634694_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 301.0
HKD3_k127_2634694_3 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 285.0
HKD3_k127_2634694_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000004394 199.0
HKD3_k127_2634694_5 AraC-type transcriptional regulator N-terminus - - - 0.00000000000000000000000000000000000000000000000000008012 188.0
HKD3_k127_2634694_6 DinB family - - - 0.00000000000000000000000000000000000000000000001384 177.0
HKD3_k127_2634694_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000002527 103.0
HKD3_k127_2634694_8 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000005236 68.0
HKD3_k127_2634694_9 RESPONSE REGULATOR receiver - - - 0.00002678 52.0
HKD3_k127_2646303_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 524.0
HKD3_k127_2646303_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 452.0
HKD3_k127_2646303_10 - - - - 0.0000000000000000000000000000000004234 136.0
HKD3_k127_2646303_11 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000001659 121.0
HKD3_k127_2646303_12 Domain of unknown function (DUF374) - - - 0.0000000000000000000000001605 114.0
HKD3_k127_2646303_13 Stage II sporulation protein - - - 0.0000000000000000003684 94.0
HKD3_k127_2646303_14 - - - - 0.0000000000000006088 89.0
HKD3_k127_2646303_15 lysyltransferase activity K07027 - - 0.0000000005205 72.0
HKD3_k127_2646303_16 Resolvase - - - 0.00005007 50.0
HKD3_k127_2646303_2 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 424.0
HKD3_k127_2646303_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 289.0
HKD3_k127_2646303_4 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001779 289.0
HKD3_k127_2646303_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
HKD3_k127_2646303_6 LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005241 254.0
HKD3_k127_2646303_7 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000003833 229.0
HKD3_k127_2646303_8 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000000000000000000000000000000000001834 163.0
HKD3_k127_2646303_9 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000001406 142.0
HKD3_k127_2670469_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002379 245.0
HKD3_k127_2670469_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000003157 81.0
HKD3_k127_2679037_0 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 442.0
HKD3_k127_2679037_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000001009 150.0
HKD3_k127_2681189_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 422.0
HKD3_k127_2681189_1 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000005153 159.0
HKD3_k127_2681189_2 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000002915 132.0
HKD3_k127_2681189_3 methyltransferase activity - - - 0.000000000000000000005151 100.0
HKD3_k127_2681189_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000001322 93.0
HKD3_k127_2681189_5 Peptidase dimerisation domain K01295 - 3.4.17.11 0.000000001946 61.0
HKD3_k127_270560_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 419.0
HKD3_k127_270560_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007332 288.0
HKD3_k127_270560_2 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001957 284.0
HKD3_k127_270560_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008124 282.0
HKD3_k127_270560_4 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000001901 178.0
HKD3_k127_270560_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000001708 168.0
HKD3_k127_270560_6 Peptidase family M28 - - - 0.00000000000000000004094 94.0
HKD3_k127_2716468_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 5.965e-286 900.0
HKD3_k127_2716468_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.699e-251 788.0
HKD3_k127_2716468_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000005794 59.0
HKD3_k127_2716468_11 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.000006854 57.0
HKD3_k127_2716468_12 Peptidase S24-like - - - 0.00002286 55.0
HKD3_k127_2716468_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 6.431e-217 681.0
HKD3_k127_2716468_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000005508 207.0
HKD3_k127_2716468_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000001345 194.0
HKD3_k127_2716468_5 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000002286 206.0
HKD3_k127_2716468_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000002607 128.0
HKD3_k127_2716468_7 recA bacterial DNA recombination protein - - - 0.0000000000000000000002105 109.0
HKD3_k127_2716468_8 Lipopolysaccharide-assembly - - - 0.00000000000002333 81.0
HKD3_k127_2716468_9 Helix-turn-helix XRE-family like proteins - - - 0.0000002301 62.0
HKD3_k127_2722896_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 497.0
HKD3_k127_276188_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.794e-266 846.0
HKD3_k127_276188_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.094e-219 691.0
HKD3_k127_276188_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.737e-211 668.0
HKD3_k127_276188_3 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000003379 233.0
HKD3_k127_276188_4 Thioesterase superfamily - - - 0.0000000000000009818 83.0
HKD3_k127_276188_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000001127 81.0
HKD3_k127_2801021_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 327.0
HKD3_k127_2801021_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000004851 165.0
HKD3_k127_2801021_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000004983 113.0
HKD3_k127_2813604_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 478.0
HKD3_k127_2813604_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000002615 177.0
HKD3_k127_2813604_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000003166 148.0
HKD3_k127_2835015_0 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 368.0
HKD3_k127_2835015_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000002372 182.0
HKD3_k127_2835015_2 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000003449 202.0
HKD3_k127_2854229_0 Carbon starvation protein K06200 - - 1.573e-215 686.0
HKD3_k127_2854229_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 511.0
HKD3_k127_2854229_2 Tetratricopeptide repeat - - - 0.000007151 59.0
HKD3_k127_2855311_0 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000272 106.0
HKD3_k127_2855311_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000001743 102.0
HKD3_k127_2855311_2 TonB-dependent receptor plug - - - 0.0000000000004556 71.0
HKD3_k127_2855311_3 peptidase M36 - - - 0.000005587 58.0
HKD3_k127_2880158_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 409.0
HKD3_k127_2880158_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 355.0
HKD3_k127_2880158_2 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003729 286.0
HKD3_k127_2880158_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
HKD3_k127_2880158_4 PFAM Phosphate-starvation-inducible - - - 0.000000000000000000000000000000000000000000000000009847 189.0
HKD3_k127_2880158_5 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000003074 134.0
HKD3_k127_2880158_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0005061 44.0
HKD3_k127_2910249_0 ABC transporter transmembrane K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 483.0
HKD3_k127_2916922_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 499.0
HKD3_k127_2916922_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 370.0
HKD3_k127_2916922_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008218 286.0
HKD3_k127_2916922_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000001624 122.0
HKD3_k127_2916922_4 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000008223 86.0
HKD3_k127_2958603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1273.0
HKD3_k127_2958603_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1076.0
HKD3_k127_2958603_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000004915 217.0
HKD3_k127_2958603_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000002091 104.0
HKD3_k127_2958603_4 pfam yhs - - - 0.0000000000004556 71.0
HKD3_k127_3041915_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 399.0
HKD3_k127_3041915_1 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000000000000000000000000000000000000124 221.0
HKD3_k127_3041915_2 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000001244 173.0
HKD3_k127_3041915_3 O-antigen ligase like membrane protein - - - 0.000000000000000000000000519 120.0
HKD3_k127_3092802_0 Cytochrome c554 and c-prime - - - 0.0 1050.0
HKD3_k127_3092802_1 Arylsulfatase - - - 1.663e-268 841.0
HKD3_k127_3092802_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 473.0
HKD3_k127_3092802_3 PFAM regulatory protein LuxR K13041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
HKD3_k127_3092802_4 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000004808 72.0
HKD3_k127_3142929_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 465.0
HKD3_k127_3142929_1 PFAM multicopper oxidase type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001357 246.0
HKD3_k127_3142929_2 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000579 203.0
HKD3_k127_3142929_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000007337 159.0
HKD3_k127_3142929_4 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.00000000000000000000000000000000511 149.0
HKD3_k127_3142929_5 Peptidase m28 - - - 0.00000000001686 71.0
HKD3_k127_317006_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 461.0
HKD3_k127_317006_1 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008125 274.0
HKD3_k127_317006_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD3_k127_317006_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
HKD3_k127_317006_4 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000004259 116.0
HKD3_k127_317006_5 - - - - 0.0000000000006172 81.0
HKD3_k127_3179618_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1262.0
HKD3_k127_3179618_1 Protein export membrane protein K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 607.0
HKD3_k127_3179618_2 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
HKD3_k127_3179618_3 PFAM Polyphosphate kinase 2 K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 422.0
HKD3_k127_3179618_4 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000577 221.0
HKD3_k127_3179618_5 AsmA family K07289 - - 0.000002747 61.0
HKD3_k127_3192221_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 411.0
HKD3_k127_3192221_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000000000000000000000000006302 121.0
HKD3_k127_3385867_0 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000008407 188.0
HKD3_k127_3385867_1 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000001531 102.0
HKD3_k127_3385867_3 Cytochrome C biogenesis protein K05516 - - 0.000004303 59.0
HKD3_k127_3438210_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 8.041e-251 803.0
HKD3_k127_3438210_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 510.0
HKD3_k127_3438210_10 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000002105 74.0
HKD3_k127_3438210_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000634 58.0
HKD3_k127_3438210_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000001799 55.0
HKD3_k127_3438210_13 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00008004 54.0
HKD3_k127_3438210_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 410.0
HKD3_k127_3438210_3 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002371 292.0
HKD3_k127_3438210_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000265 194.0
HKD3_k127_3438210_5 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000006701 184.0
HKD3_k127_3438210_6 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000005899 173.0
HKD3_k127_3438210_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000003258 167.0
HKD3_k127_3438210_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000002823 162.0
HKD3_k127_3438210_9 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000002625 155.0
HKD3_k127_3479498_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.074e-254 797.0
HKD3_k127_3479498_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000008737 209.0
HKD3_k127_353554_0 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002308 263.0
HKD3_k127_353554_1 Bacterial membrane protein YfhO - - - 0.00000000000000003343 94.0
HKD3_k127_3646891_0 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
HKD3_k127_3646891_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD3_k127_3651540_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 2.083e-282 899.0
HKD3_k127_3651540_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000003827 91.0
HKD3_k127_3657649_0 Bacterial sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 401.0
HKD3_k127_3657649_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 295.0
HKD3_k127_3657649_2 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000009279 229.0
HKD3_k127_3657649_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000002196 220.0
HKD3_k127_3657649_4 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000001691 196.0
HKD3_k127_3657649_5 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000006353 188.0
HKD3_k127_3657649_6 Glycosyltransferase, group 1 family protein - - - 0.000000000000000000000000000000007849 143.0
HKD3_k127_3657649_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000002264 94.0
HKD3_k127_3657649_8 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000004843 92.0
HKD3_k127_3657649_9 Enoyl-CoA hydratase/isomerase - - - 0.0000002606 61.0
HKD3_k127_3661892_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 528.0
HKD3_k127_3661892_1 - - - - 0.000000000004399 78.0
HKD3_k127_3661892_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000007033 68.0
HKD3_k127_3661892_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001097 66.0
HKD3_k127_3661892_4 Putative adhesin - - - 0.00004358 55.0
HKD3_k127_3661892_5 Phage integrase family - - - 0.0002299 47.0
HKD3_k127_3674689_0 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 496.0
HKD3_k127_3674689_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 312.0
HKD3_k127_3674689_10 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000007388 116.0
HKD3_k127_3674689_11 Membrane - - - 0.0000001842 62.0
HKD3_k127_3674689_12 RHS Repeat - - - 0.000006686 60.0
HKD3_k127_3674689_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 308.0
HKD3_k127_3674689_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003676 287.0
HKD3_k127_3674689_4 Belongs to the LTA synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007563 298.0
HKD3_k127_3674689_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
HKD3_k127_3674689_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000005556 177.0
HKD3_k127_3674689_7 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000005751 165.0
HKD3_k127_3674689_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000002513 129.0
HKD3_k127_3674689_9 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000492 136.0
HKD3_k127_3697501_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000005533 222.0
HKD3_k127_3697501_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000005796 190.0
HKD3_k127_3697501_2 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.000000000002974 79.0
HKD3_k127_3700257_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 1.983e-209 668.0
HKD3_k127_3700257_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 359.0
HKD3_k127_3700257_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 326.0
HKD3_k127_3700257_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 308.0
HKD3_k127_3700257_4 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001182 258.0
HKD3_k127_3700257_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000001651 249.0
HKD3_k127_3700257_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 239.0
HKD3_k127_3700257_7 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000005315 96.0
HKD3_k127_3700257_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000006816 87.0
HKD3_k127_3701853_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 2.253e-198 629.0
HKD3_k127_3701853_1 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 385.0
HKD3_k127_3701853_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000002091 202.0
HKD3_k127_3701853_11 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000235 191.0
HKD3_k127_3701853_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001061 194.0
HKD3_k127_3701853_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002091 192.0
HKD3_k127_3701853_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000001455 176.0
HKD3_k127_3701853_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000006515 175.0
HKD3_k127_3701853_16 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000004642 169.0
HKD3_k127_3701853_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000305 138.0
HKD3_k127_3701853_18 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000004225 139.0
HKD3_k127_3701853_19 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000001709 133.0
HKD3_k127_3701853_2 Dihydroxyacetone kinase family K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 375.0
HKD3_k127_3701853_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000002558 129.0
HKD3_k127_3701853_21 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000005369 131.0
HKD3_k127_3701853_22 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000002369 130.0
HKD3_k127_3701853_23 Regulatory protein ArsR - - - 0.0000000000000000000006033 101.0
HKD3_k127_3701853_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000003218 84.0
HKD3_k127_3701853_25 Ribosomal protein L36 K02919 - - 0.0000000000002467 70.0
HKD3_k127_3701853_26 Tetratricopeptide repeat protein - - - 0.0000001182 59.0
HKD3_k127_3701853_28 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000001319 59.0
HKD3_k127_3701853_29 TIGRFAM TonB family C-terminal domain K03832 - - 0.000004479 59.0
HKD3_k127_3701853_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 369.0
HKD3_k127_3701853_30 Psort location CytoplasmicMembrane, score - - - 0.0002812 53.0
HKD3_k127_3701853_4 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 363.0
HKD3_k127_3701853_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HKD3_k127_3701853_6 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
HKD3_k127_3701853_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 283.0
HKD3_k127_3701853_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD3_k127_3701853_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001321 237.0
HKD3_k127_3706418_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000002592 226.0
HKD3_k127_3706418_1 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000009046 70.0
HKD3_k127_3717325_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 531.0
HKD3_k127_3717325_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 317.0
HKD3_k127_3717325_2 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000002793 141.0
HKD3_k127_3744269_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 521.0
HKD3_k127_3744269_1 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 347.0
HKD3_k127_3744269_10 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000001638 142.0
HKD3_k127_3744269_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000155 134.0
HKD3_k127_3744269_12 outer membrane efflux protein - - - 0.00000000000000000000000000004981 127.0
HKD3_k127_3744269_13 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000003834 114.0
HKD3_k127_3744269_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000002303 119.0
HKD3_k127_3744269_15 Serine aminopeptidase, S33 - - - 0.000000000000000000003404 104.0
HKD3_k127_3744269_16 DinB family - - - 0.0000000001614 70.0
HKD3_k127_3744269_2 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 263.0
HKD3_k127_3744269_3 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005296 269.0
HKD3_k127_3744269_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HKD3_k127_3744269_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K15876 - - 0.00000000000000000000000000000000000000000001115 169.0
HKD3_k127_3744269_6 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000006762 158.0
HKD3_k127_3744269_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000177 160.0
HKD3_k127_3744269_8 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000001517 155.0
HKD3_k127_3744269_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000006962 150.0
HKD3_k127_3751865_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000001574 124.0
HKD3_k127_3751865_1 Pfam:N_methyl_2 K02650 - - 0.00000000000000000000006984 106.0
HKD3_k127_3751865_2 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000006438 82.0
HKD3_k127_3817731_0 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000001621 140.0
HKD3_k127_3817731_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000829 96.0
HKD3_k127_3837935_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 367.0
HKD3_k127_3837935_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 349.0
HKD3_k127_3840860_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 490.0
HKD3_k127_3840860_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 429.0
HKD3_k127_3840860_2 - - - - 0.00000000000000000000000000000000000000000000000000003361 199.0
HKD3_k127_3840860_3 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000003381 131.0
HKD3_k127_3840860_4 oxidoreductase activity - - - 0.00000000000000001709 96.0
HKD3_k127_3840860_5 bacterial OsmY and nodulation domain - - - 0.0000000000000009799 86.0
HKD3_k127_3840860_6 oxidoreductase activity - - - 0.000000000000004892 90.0
HKD3_k127_3840860_7 Bacterial regulatory proteins, tetR family - - - 0.0000002203 60.0
HKD3_k127_3840860_8 Psort location Cytoplasmic, score - - - 0.0001197 55.0
HKD3_k127_3842005_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 549.0
HKD3_k127_3842005_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 541.0
HKD3_k127_3842005_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002462 269.0
HKD3_k127_3842005_3 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000005729 149.0
HKD3_k127_3842005_4 - K01992 - - 0.0000000000000000000000000006129 128.0
HKD3_k127_3842005_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000008671 124.0
HKD3_k127_3842005_7 - - - - 0.000006949 57.0
HKD3_k127_3858768_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 301.0
HKD3_k127_3858768_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD3_k127_3858768_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000005397 152.0
HKD3_k127_3858768_3 PFAM Glycosyl transferase family 2 - - - 0.000005968 55.0
HKD3_k127_386685_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 1.179e-218 702.0
HKD3_k127_386685_1 B12 binding domain - - - 1.074e-203 645.0
HKD3_k127_386685_2 prohibitin homologues K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 407.0
HKD3_k127_386685_3 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 334.0
HKD3_k127_386685_4 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
HKD3_k127_386685_5 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000241 225.0
HKD3_k127_386685_6 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000002782 96.0
HKD3_k127_386685_7 Rubrerythrin - - - 0.0009897 48.0
HKD3_k127_3871363_0 DNA integration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HKD3_k127_3871363_1 Transcriptional regulator K04033 - - 0.000000000000000000000000009077 122.0
HKD3_k127_3871363_2 - - - - 0.000000000008435 70.0
HKD3_k127_3871363_3 Transcriptional regulator K03655,K12573 - 3.6.4.12 0.0000001351 64.0
HKD3_k127_3874842_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000002198 245.0
HKD3_k127_3887395_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 529.0
HKD3_k127_3905453_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000004584 193.0
HKD3_k127_3905453_1 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000003406 174.0
HKD3_k127_3905453_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000001643 168.0
HKD3_k127_3905453_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001647 151.0
HKD3_k127_3905453_4 Alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000004324 136.0
HKD3_k127_3905453_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000009584 108.0
HKD3_k127_3905453_6 Forkhead associated domain - - - 0.000000000008377 75.0
HKD3_k127_3905453_7 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000001371 66.0
HKD3_k127_3905453_8 TonB C terminal K03832 - - 0.000000085 63.0
HKD3_k127_3905453_9 RDD family - - - 0.000003333 58.0
HKD3_k127_3911880_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 488.0
HKD3_k127_3911880_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 277.0
HKD3_k127_3911880_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000008878 234.0
HKD3_k127_3911880_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000001094 68.0
HKD3_k127_3911880_4 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000001525 66.0
HKD3_k127_3916480_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 613.0
HKD3_k127_3916480_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 434.0
HKD3_k127_3916480_2 elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 359.0
HKD3_k127_3916480_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000008266 265.0
HKD3_k127_3916480_4 DNA polymerase beta thumb K02347 - - 0.000000000000000000000000000000000345 147.0
HKD3_k127_3916480_5 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000007971 111.0
HKD3_k127_3916480_6 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000002243 108.0
HKD3_k127_3916480_7 Transcriptional regulator - - - 0.00005315 55.0
HKD3_k127_3923876_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000207 214.0
HKD3_k127_3923876_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000001162 199.0
HKD3_k127_3948681_0 butyrate kinase activity K00625,K00929,K04020,K13788 GO:0003674,GO:0003824,GO:0006950,GO:0008150,GO:0008959,GO:0009266,GO:0009408,GO:0009628,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0050896 2.3.1.8,2.7.2.7 1e-323 1005.0
HKD3_k127_3948681_1 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 544.0
HKD3_k127_3948681_2 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 333.0
HKD3_k127_3948681_3 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 0.0000005374 55.0
HKD3_k127_3948681_4 Rubrerythrin - - - 0.000002829 53.0
HKD3_k127_3949413_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1761.0
HKD3_k127_3949413_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 429.0
HKD3_k127_3949413_2 PFAM Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 445.0
HKD3_k127_3949413_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 402.0
HKD3_k127_3949413_4 2,3-bisphosphoglycerate-independent phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 387.0
HKD3_k127_3949413_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 329.0
HKD3_k127_3949413_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000003472 143.0
HKD3_k127_3960613_0 belongs to the aldehyde dehydrogenase family - - - 6.358e-198 635.0
HKD3_k127_3960613_1 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000001685 173.0
HKD3_k127_3960613_2 Peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.000000000000006501 83.0
HKD3_k127_4011110_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 472.0
HKD3_k127_4011110_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 390.0
HKD3_k127_4011110_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
HKD3_k127_4011110_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 302.0
HKD3_k127_4011110_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HKD3_k127_4011110_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000007006 178.0
HKD3_k127_4011110_6 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.000000000000000000000000000000005943 139.0
HKD3_k127_404140_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1019.0
HKD3_k127_404140_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 607.0
HKD3_k127_404140_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 447.0
HKD3_k127_404140_3 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 399.0
HKD3_k127_404140_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000001064 190.0
HKD3_k127_404140_5 PFAM peptidase U34 dipeptidase - - - 0.000000000000000000001532 98.0
HKD3_k127_404140_6 - - - - 0.000000000000000000417 91.0
HKD3_k127_404140_7 oxidoreductase activity - - - 0.0000000000002477 83.0
HKD3_k127_404140_8 Winged helix-turn-helix domain (DUF2582) - - - 0.000000000003674 69.0
HKD3_k127_404140_9 oxidoreductase activity - - - 0.0000001887 64.0
HKD3_k127_4047286_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 586.0
HKD3_k127_4047286_1 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 416.0
HKD3_k127_4047286_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000044 222.0
HKD3_k127_4047286_3 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
HKD3_k127_4047286_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000004157 157.0
HKD3_k127_4047286_5 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000000000001831 149.0
HKD3_k127_404836_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000003343 157.0
HKD3_k127_404836_1 Receptor family ligand binding region K01999 - - 0.0000000000003591 81.0
HKD3_k127_4072862_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 621.0
HKD3_k127_4072862_1 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000000000119 206.0
HKD3_k127_4072862_2 kinase activity K02850 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.00000000000000000000000000000000000000006106 168.0
HKD3_k127_4072862_3 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000002347 149.0
HKD3_k127_4072862_4 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000001371 51.0
HKD3_k127_4078194_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 484.0
HKD3_k127_4078194_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
HKD3_k127_4078194_2 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000849 212.0
HKD3_k127_4078194_3 secreted acid phosphatase - - - 0.00000000000000000002927 98.0
HKD3_k127_4097782_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 441.0
HKD3_k127_4097782_1 Outer membrane protein beta-barrel family K16087,K16092 - - 0.000000000000000000000000000000000000000000000000000007743 209.0
HKD3_k127_4097782_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000001518 73.0
HKD3_k127_4120025_0 iron-nicotianamine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 394.0
HKD3_k127_4120025_1 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000002987 181.0
HKD3_k127_4120025_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000004003 106.0
HKD3_k127_4120025_3 Protein of unknown function (DUF2914) - - - 0.00000000000032 81.0
HKD3_k127_4206212_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 580.0
HKD3_k127_4206212_1 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 452.0
HKD3_k127_4206212_2 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 373.0
HKD3_k127_4206212_3 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 329.0
HKD3_k127_4206212_4 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000001254 213.0
HKD3_k127_4206212_5 Melibiase K07407 - 3.2.1.22 0.0008264 43.0
HKD3_k127_4297904_0 PFAM Type II secretion system protein E K02652 - - 1.362e-213 677.0
HKD3_k127_4297904_1 glycosyl hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 556.0
HKD3_k127_4297904_2 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 301.0
HKD3_k127_4297904_3 Belongs to the GSP D family K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000129 298.0
HKD3_k127_4297904_4 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000001546 177.0
HKD3_k127_4297904_5 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000003667 127.0
HKD3_k127_4297904_6 Pilus assembly protein K02662 - - 0.00000001079 67.0
HKD3_k127_4297904_7 PFAM Fimbrial assembly family protein K02663 - - 0.0000002301 61.0
HKD3_k127_4318361_0 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000000009019 117.0
HKD3_k127_4318361_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000006488 109.0
HKD3_k127_4322012_0 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 344.0
HKD3_k127_4322012_1 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 316.0
HKD3_k127_4322012_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000003667 260.0
HKD3_k127_4322012_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001556 229.0
HKD3_k127_4322012_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000118 198.0
HKD3_k127_4322012_5 PspC domain K03973 - - 0.0000000001387 68.0
HKD3_k127_4323726_0 Tricorn protease homolog K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 556.0
HKD3_k127_4323726_1 ECF sigma factor K03088 - - 0.00000000000000000000000000000000003927 142.0
HKD3_k127_4382328_0 magnesium chelatase K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 549.0
HKD3_k127_4382328_1 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 455.0
HKD3_k127_4382328_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 396.0
HKD3_k127_4382328_3 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007268 274.0
HKD3_k127_4382328_4 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000008674 238.0
HKD3_k127_4382328_5 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
HKD3_k127_4382328_6 PFAM Ferritin Dps family protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000001298 182.0
HKD3_k127_4382328_7 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000007981 150.0
HKD3_k127_4382328_8 Transcription factor zinc-finger K09981 - - 0.00000000000000000000002957 106.0
HKD3_k127_440698_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000002193 236.0
HKD3_k127_440698_1 class II (D K K01893 - 6.1.1.22 0.00000000000000000000000000000000000009024 142.0
HKD3_k127_440698_2 4Fe-4S dicluster domain - - - 0.0000000000000000007523 87.0
HKD3_k127_4499717_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 481.0
HKD3_k127_4499717_1 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 405.0
HKD3_k127_45190_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 314.0
HKD3_k127_45190_1 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000003038 177.0
HKD3_k127_45190_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000006534 157.0
HKD3_k127_4548151_0 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009351 472.0
HKD3_k127_4548151_1 iron-nicotianamine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 352.0
HKD3_k127_4548151_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
HKD3_k127_4548151_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000002691 158.0
HKD3_k127_4548151_4 Thioredoxin-like - - - 0.0000000000000000001339 96.0
HKD3_k127_4548151_5 Inter-alpha-trypsin inhibitor heavy chain - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.00000001316 66.0
HKD3_k127_4548151_6 Belongs to the ompA family K03286 - - 0.0002602 51.0
HKD3_k127_4564109_0 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000001476 213.0
HKD3_k127_4564109_1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.0000000000000000000000000000000000000000002565 165.0
HKD3_k127_4564109_2 Ion channel - - - 0.00000000000000004378 93.0
HKD3_k127_457538_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000002159 150.0
HKD3_k127_457538_1 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.0000000000000000000007407 109.0
HKD3_k127_457538_2 PFAM PEGA domain - - - 0.000003371 57.0
HKD3_k127_4597176_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.086e-273 866.0
HKD3_k127_4690043_0 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
HKD3_k127_4690043_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000003729 155.0
HKD3_k127_4690043_3 - - - - 0.0000000000000003079 86.0
HKD3_k127_4690043_4 leucine-zipper of insertion element IS481 - - - 0.000000001617 61.0
HKD3_k127_4701451_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.111e-228 737.0
HKD3_k127_4701451_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 491.0
HKD3_k127_4701451_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 466.0
HKD3_k127_4701451_3 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 394.0
HKD3_k127_4701451_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003043 265.0
HKD3_k127_4701451_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000002575 236.0
HKD3_k127_4701451_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000271 223.0
HKD3_k127_4701451_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000002679 171.0
HKD3_k127_4701451_8 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000622 150.0
HKD3_k127_4701451_9 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000004765 140.0
HKD3_k127_472894_0 Outer membrane receptor - - - 0.00000000000000000000000000000000000000009482 175.0
HKD3_k127_4835268_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 256.0
HKD3_k127_4835268_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000001011 193.0
HKD3_k127_4835443_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 2.715e-255 824.0
HKD3_k127_4835443_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 501.0
HKD3_k127_4835443_2 - - - - 0.000000000000000000000000000000000002493 143.0
HKD3_k127_4861567_0 Elongation factor G, domain IV K02355 - - 8.857e-200 647.0
HKD3_k127_4861567_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 592.0
HKD3_k127_4861567_10 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001661 141.0
HKD3_k127_4861567_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000001235 144.0
HKD3_k127_4861567_12 DinB superfamily - - - 0.0000000000000000000000000000004484 131.0
HKD3_k127_4861567_13 Cold shock protein K03704 - - 0.0000000000000000000000000002249 116.0
HKD3_k127_4861567_14 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000001632 122.0
HKD3_k127_4861567_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000185 121.0
HKD3_k127_4861567_16 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000009754 100.0
HKD3_k127_4861567_17 Smr domain - - - 0.00000000000000000001709 104.0
HKD3_k127_4861567_18 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001523 74.0
HKD3_k127_4861567_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 419.0
HKD3_k127_4861567_3 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 354.0
HKD3_k127_4861567_4 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 305.0
HKD3_k127_4861567_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 301.0
HKD3_k127_4861567_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
HKD3_k127_4861567_7 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
HKD3_k127_4861567_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001808 143.0
HKD3_k127_4861567_9 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000006823 141.0
HKD3_k127_4883572_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 386.0
HKD3_k127_4883572_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 351.0
HKD3_k127_4883572_2 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004826 247.0
HKD3_k127_4883572_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000008389 247.0
HKD3_k127_4883572_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000001384 225.0
HKD3_k127_4883572_5 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000002692 120.0
HKD3_k127_4883572_6 PFAM phosphoryl transfer system HPr K11189 - - 0.000000000000000000000008473 103.0
HKD3_k127_4883572_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000006122 100.0
HKD3_k127_4883572_8 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000002514 96.0
HKD3_k127_488553_0 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 459.0
HKD3_k127_488553_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 442.0
HKD3_k127_488553_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000002473 127.0
HKD3_k127_488553_3 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.00000000000000000000000000202 118.0
HKD3_k127_4886509_0 Tricorn protease homolog - - - 0.0 1433.0
HKD3_k127_4886509_1 Oligoendopeptidase f - - - 7.563e-228 728.0
HKD3_k127_4886509_2 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 452.0
HKD3_k127_4886509_3 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 412.0
HKD3_k127_4886509_4 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 356.0
HKD3_k127_4886509_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 340.0
HKD3_k127_4886509_6 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
HKD3_k127_4886509_7 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000001217 168.0
HKD3_k127_4886509_8 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000004099 166.0
HKD3_k127_4886509_9 4Fe-4S binding domain - - - 0.000000000005559 77.0
HKD3_k127_4900249_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 533.0
HKD3_k127_4900249_1 Protease prsW family - - - 0.00004809 54.0
HKD3_k127_4906952_0 N,N-dimethylaniline monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 599.0
HKD3_k127_4906952_1 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 417.0
HKD3_k127_4906952_2 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000198 167.0
HKD3_k127_4906952_3 SnoaL-like domain - - - 0.00000000000000000007645 100.0
HKD3_k127_4906952_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000003284 78.0
HKD3_k127_4906952_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000005732 51.0
HKD3_k127_4932624_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000007342 220.0
HKD3_k127_4932624_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000003421 203.0
HKD3_k127_4943349_0 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 452.0
HKD3_k127_4943349_1 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 398.0
HKD3_k127_4943349_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 245.0
HKD3_k127_4949809_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 503.0
HKD3_k127_4949809_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000002919 98.0
HKD3_k127_4955680_0 Zinc-binding dehydrogenase K22231 - - 4.244e-200 630.0
HKD3_k127_4955680_1 Outer membrane protein beta-barrel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 524.0
HKD3_k127_4955680_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 504.0
HKD3_k127_4955680_3 PFAM Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 520.0
HKD3_k127_4955680_4 ATPases associated with a variety of cellular activities K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 484.0
HKD3_k127_4955680_5 Belongs to the binding-protein-dependent transport system permease family K10439,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 422.0
HKD3_k127_4955680_6 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 334.0
HKD3_k127_4955680_7 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
HKD3_k127_4955680_8 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 289.0
HKD3_k127_4955680_9 3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003151 267.0
HKD3_k127_4970766_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.435e-232 741.0
HKD3_k127_4970766_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 560.0
HKD3_k127_4970766_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 361.0
HKD3_k127_4970766_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001306 268.0
HKD3_k127_4970766_4 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000006335 207.0
HKD3_k127_4970766_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000001451 193.0
HKD3_k127_4970766_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000194 189.0
HKD3_k127_4970766_7 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000000002217 127.0
HKD3_k127_4970766_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000236 83.0
HKD3_k127_4970766_9 general secretion pathway protein K02456,K02650 - - 0.0000000000000009085 87.0
HKD3_k127_5007917_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 361.0
HKD3_k127_5007917_1 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000133 243.0
HKD3_k127_5007917_2 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000002414 196.0
HKD3_k127_5033639_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1344.0
HKD3_k127_5033639_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 598.0
HKD3_k127_5033639_2 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
HKD3_k127_5033806_0 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 324.0
HKD3_k127_5033806_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000005946 119.0
HKD3_k127_5105726_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 340.0
HKD3_k127_5105726_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HKD3_k127_5105726_2 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001995 281.0
HKD3_k127_5105726_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001297 279.0
HKD3_k127_5105726_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
HKD3_k127_5105726_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000005474 196.0
HKD3_k127_5105726_6 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000002608 144.0
HKD3_k127_5105726_7 Pfam AhpC TSA family - - - 0.0000000000000000000002086 106.0
HKD3_k127_5105726_8 Histidine kinase - - - 0.00000000000000003412 94.0
HKD3_k127_5105726_9 Glycosyl transferase, family 2 - - - 0.0000000000000003774 90.0
HKD3_k127_512367_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1286.0
HKD3_k127_512367_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 532.0
HKD3_k127_512367_10 Sulfatase - - - 0.000000000000000000009912 108.0
HKD3_k127_512367_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 531.0
HKD3_k127_512367_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
HKD3_k127_512367_4 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 288.0
HKD3_k127_512367_5 geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002553 296.0
HKD3_k127_512367_6 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000009054 251.0
HKD3_k127_512367_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000001145 229.0
HKD3_k127_512367_8 DinB family - - - 0.000000000000000000000000000000000000000009398 160.0
HKD3_k127_512367_9 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000001758 166.0
HKD3_k127_5133467_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003198 274.0
HKD3_k127_5133467_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000002989 254.0
HKD3_k127_5133467_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000004378 214.0
HKD3_k127_5133467_3 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000013 142.0
HKD3_k127_5133467_4 Aminotransferase, class I - - - 0.0001499 45.0
HKD3_k127_5137302_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 1.13e-234 739.0
HKD3_k127_5137302_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.868e-198 647.0
HKD3_k127_5137302_10 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000002069 154.0
HKD3_k127_5137302_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001633 128.0
HKD3_k127_5137302_12 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000303 133.0
HKD3_k127_5137302_13 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000004164 121.0
HKD3_k127_5137302_14 Ribosome-binding factor A - - - 0.00000000000000002964 89.0
HKD3_k127_5137302_15 succinate dehydrogenase activity K00242,K00246 - - 0.0000000000006978 73.0
HKD3_k127_5137302_16 Protein conserved in bacteria K09764 - - 0.0000000006086 64.0
HKD3_k127_5137302_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 571.0
HKD3_k127_5137302_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
HKD3_k127_5137302_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 374.0
HKD3_k127_5137302_5 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HKD3_k127_5137302_6 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
HKD3_k127_5137302_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HKD3_k127_5137302_8 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000001859 239.0
HKD3_k127_5137302_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000002533 218.0
HKD3_k127_5147174_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 335.0
HKD3_k127_5147174_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000002716 70.0
HKD3_k127_5147174_2 - - - - 0.0000000004285 65.0
HKD3_k127_5154293_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 5.943e-290 906.0
HKD3_k127_5154293_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 318.0
HKD3_k127_5154293_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD3_k127_5154293_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002911 257.0
HKD3_k127_5154293_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
HKD3_k127_5154293_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000006958 192.0
HKD3_k127_5154293_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000001026 170.0
HKD3_k127_5161567_0 Glycosyltransferase like family 2 - - - 2.865e-198 644.0
HKD3_k127_5161567_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.662e-197 624.0
HKD3_k127_5161567_10 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000009319 129.0
HKD3_k127_5161567_11 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000001615 136.0
HKD3_k127_5161567_12 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000005817 131.0
HKD3_k127_5161567_13 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000008374 91.0
HKD3_k127_5161567_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HKD3_k127_5161567_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 325.0
HKD3_k127_5161567_4 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000482 291.0
HKD3_k127_5161567_5 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD3_k127_5161567_6 ABC transporter, permease protein K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004233 258.0
HKD3_k127_5161567_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002922 247.0
HKD3_k127_5161567_8 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000000000001854 207.0
HKD3_k127_5161567_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000002531 169.0
HKD3_k127_5201535_0 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 428.0
HKD3_k127_5201535_1 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 295.0
HKD3_k127_5201535_2 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000006877 162.0
HKD3_k127_5201535_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000005134 137.0
HKD3_k127_5201535_4 protein-disulfide reductase activity - - - 0.00000000000000000000000006252 117.0
HKD3_k127_5201535_5 - - - - 0.0000000000000000000005279 105.0
HKD3_k127_5201535_6 Protein of unknown function DUF47 K07220 - - 0.000000000000000000001682 96.0
HKD3_k127_5228258_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 1.681e-200 639.0
HKD3_k127_5228258_1 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 481.0
HKD3_k127_5228258_2 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
HKD3_k127_5228258_4 Domain of unknown function (DUF4156) - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00004835 51.0
HKD3_k127_5237600_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 460.0
HKD3_k127_5237600_1 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007367 252.0
HKD3_k127_5237600_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000002321 225.0
HKD3_k127_5237600_3 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000001759 234.0
HKD3_k127_5237600_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000001403 182.0
HKD3_k127_5237600_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000001147 169.0
HKD3_k127_5237600_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000000001748 129.0
HKD3_k127_5237600_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000001669 122.0
HKD3_k127_5237600_8 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000001318 110.0
HKD3_k127_5237600_9 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000001907 80.0
HKD3_k127_5267681_0 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 471.0
HKD3_k127_5267681_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 439.0
HKD3_k127_5267681_2 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
HKD3_k127_5267681_3 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000004917 148.0
HKD3_k127_5311393_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 389.0
HKD3_k127_5311393_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
HKD3_k127_5311393_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000007731 255.0
HKD3_k127_5311393_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000002168 243.0
HKD3_k127_5311393_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000005227 214.0
HKD3_k127_5311393_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000006062 181.0
HKD3_k127_5311393_6 metal-sulfur cluster biosynthetic - - - 0.00000000000000000000001263 104.0
HKD3_k127_5311393_7 PFAM YbbR family protein - - - 0.00000000000000000000545 105.0
HKD3_k127_5311393_8 DSBA-like thioredoxin domain - - - 0.0000000000000000443 95.0
HKD3_k127_5311393_9 protein kinase activity - - - 0.0000000000000002824 94.0
HKD3_k127_5321923_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1037.0
HKD3_k127_5321923_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 430.0
HKD3_k127_5321923_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000001562 161.0
HKD3_k127_5321923_3 DinB family - - - 0.000000000000000000000001627 109.0
HKD3_k127_5321923_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000005722 96.0
HKD3_k127_5324865_0 PFAM ABC transporter K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 358.0
HKD3_k127_5324865_1 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 313.0
HKD3_k127_5324865_2 Glycosyltransferase like family 2 K20444 - - 0.0000000000000000000000009906 114.0
HKD3_k127_5332622_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.556e-264 842.0
HKD3_k127_5332622_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 563.0
HKD3_k127_5332622_2 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 456.0
HKD3_k127_5392128_0 transferase activity, transferring acyl groups - - - 0.000000000000000000003016 105.0
HKD3_k127_5392128_1 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000001627 102.0
HKD3_k127_5392128_2 Acetyltransferase (GNAT) domain - - - 0.000000000000001732 88.0
HKD3_k127_5392128_3 Bacterial membrane protein, YfhO - - - 0.000321 52.0
HKD3_k127_5416405_0 Belongs to the ClpA ClpB family K03696 - - 1.221e-265 844.0
HKD3_k127_5416405_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 535.0
HKD3_k127_5416405_10 - - - - 0.000000000000000000000000000000000000000000000000000000003072 226.0
HKD3_k127_5416405_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000744 173.0
HKD3_k127_5416405_12 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000001947 184.0
HKD3_k127_5416405_13 spore germination K03298 - - 0.00000000000000000000000000000000000000001018 164.0
HKD3_k127_5416405_14 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000004752 124.0
HKD3_k127_5416405_15 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000008082 106.0
HKD3_k127_5416405_16 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000006499 83.0
HKD3_k127_5416405_17 ribonuclease BN K07058 - - 0.0000000000002716 83.0
HKD3_k127_5416405_18 snoRNA binding - - - 0.000002213 55.0
HKD3_k127_5416405_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 471.0
HKD3_k127_5416405_3 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
HKD3_k127_5416405_4 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 355.0
HKD3_k127_5416405_5 Surface antigen variable number K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 349.0
HKD3_k127_5416405_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
HKD3_k127_5416405_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
HKD3_k127_5416405_8 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000003065 234.0
HKD3_k127_5416405_9 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000001667 220.0
HKD3_k127_5420750_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 581.0
HKD3_k127_5420750_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 427.0
HKD3_k127_5420750_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 395.0
HKD3_k127_5420750_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002284 164.0
HKD3_k127_5420750_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000007069 148.0
HKD3_k127_5420750_5 PFAM Peptidase M23 - - - 0.0000000000000000008187 99.0
HKD3_k127_5420750_6 DoxX - - - 0.000000000000000001214 89.0
HKD3_k127_5426918_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.249e-264 828.0
HKD3_k127_5426918_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.069e-219 697.0
HKD3_k127_5426918_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 2.879e-204 651.0
HKD3_k127_5426918_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 504.0
HKD3_k127_5454054_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000009869 125.0
HKD3_k127_5454054_1 Heavy-metal resistance - - - 0.0000000000000383 80.0
HKD3_k127_5477717_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 338.0
HKD3_k127_5477717_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000001169 201.0
HKD3_k127_5477717_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002225 183.0
HKD3_k127_5477717_3 - - - - 0.000000000000000000000000000000000000006555 157.0
HKD3_k127_5494547_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 609.0
HKD3_k127_5494547_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000002416 211.0
HKD3_k127_5506734_0 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
HKD3_k127_5506734_1 EamA-like transporter family - - - 0.000000000000000000000000000000000007378 141.0
HKD3_k127_5506734_2 - - - - 0.000000005768 67.0
HKD3_k127_5550825_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 4.386e-268 853.0
HKD3_k127_5550825_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 594.0
HKD3_k127_5550825_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 443.0
HKD3_k127_5550825_3 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 411.0
HKD3_k127_5550825_4 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 321.0
HKD3_k127_5550825_5 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002763 254.0
HKD3_k127_5550825_6 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000005231 78.0
HKD3_k127_5550825_7 Amidohydrolase family K01464 - 3.5.2.2 0.000729 44.0
HKD3_k127_5558388_0 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001805 288.0
HKD3_k127_5558388_1 DinB superfamily - - - 0.000000000000000000000000002059 120.0
HKD3_k127_5559546_0 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 424.0
HKD3_k127_5559546_1 family UPF0029 - - - 0.00000000000000000000002687 104.0
HKD3_k127_5583321_0 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 286.0
HKD3_k127_5583321_1 Periplasmic or secreted lipoprotein - - - 0.0000000000000000001079 97.0
HKD3_k127_5583321_2 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000004177 83.0
HKD3_k127_5583321_3 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000003018 65.0
HKD3_k127_5602551_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 434.0
HKD3_k127_5602551_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 397.0
HKD3_k127_5602551_10 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000004538 68.0
HKD3_k127_5602551_12 PFAM peptidase - - - 0.0005376 53.0
HKD3_k127_5602551_13 domain, Protein - - - 0.0009345 52.0
HKD3_k127_5602551_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 369.0
HKD3_k127_5602551_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002475 231.0
HKD3_k127_5602551_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000527 160.0
HKD3_k127_5602551_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000003173 157.0
HKD3_k127_5602551_6 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000002932 135.0
HKD3_k127_5602551_7 von Willebrand factor, type A - - - 0.00000000000000000000000000000009746 142.0
HKD3_k127_5602551_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000006118 123.0
HKD3_k127_5602551_9 FtsX-like permease family K02004 - - 0.0000000003843 64.0
HKD3_k127_578353_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 456.0
HKD3_k127_578353_1 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 363.0
HKD3_k127_580420_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 459.0
HKD3_k127_580420_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 361.0
HKD3_k127_580420_2 COG1606 ATP-utilizing enzymes of the PP-loop superfamily K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD3_k127_580420_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002579 244.0
HKD3_k127_580420_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000002509 194.0
HKD3_k127_580420_5 Transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000147 179.0
HKD3_k127_580420_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000002799 145.0
HKD3_k127_580420_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000001503 122.0
HKD3_k127_580420_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000001002 118.0
HKD3_k127_5841699_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 545.0
HKD3_k127_5841699_1 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000001162 162.0
HKD3_k127_5841699_2 TIGRFAM methyltransferase FkbM - - - 0.0000000000000000000000000000000000000001305 164.0
HKD3_k127_5841699_3 pfam abc K09691 - - 0.0000000002612 64.0
HKD3_k127_592482_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 414.0
HKD3_k127_592482_1 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000003755 168.0
HKD3_k127_5942539_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1182.0
HKD3_k127_5942539_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 555.0
HKD3_k127_5942539_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 308.0
HKD3_k127_5942539_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000001127 217.0
HKD3_k127_5942539_4 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000001141 172.0
HKD3_k127_5942539_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000001205 180.0
HKD3_k127_5942539_6 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000003251 134.0
HKD3_k127_5942539_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001465 89.0
HKD3_k127_5942539_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000008435 87.0
HKD3_k127_5942539_9 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000001204 69.0
HKD3_k127_6034722_0 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000001877 216.0
HKD3_k127_6034722_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.00000000000000000000000000000000000000000000000006824 193.0
HKD3_k127_6034722_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000003229 127.0
HKD3_k127_6035617_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 545.0
HKD3_k127_6035617_1 PFAM Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 526.0
HKD3_k127_6035617_10 RNA-binding protein - - - 0.000000000000000004171 94.0
HKD3_k127_6035617_11 Rdx family K07401 - - 0.000000000002485 68.0
HKD3_k127_6035617_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 359.0
HKD3_k127_6035617_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 310.0
HKD3_k127_6035617_4 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001012 254.0
HKD3_k127_6035617_5 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000005994 231.0
HKD3_k127_6035617_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
HKD3_k127_6035617_7 Surface antigen K07277 - - 0.00000000000000000000000000000000000000003667 176.0
HKD3_k127_6035617_8 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000004629 173.0
HKD3_k127_6035617_9 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000007386 139.0
HKD3_k127_6046449_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 361.0
HKD3_k127_6046449_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 320.0
HKD3_k127_6046449_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 298.0
HKD3_k127_6046449_3 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001568 283.0
HKD3_k127_6046449_4 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002221 299.0
HKD3_k127_6046449_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.00000000000000000000000000000000000000000000000000000000000002633 233.0
HKD3_k127_6046449_6 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000007675 220.0
HKD3_k127_6046449_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000003568 211.0
HKD3_k127_6046449_8 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000000001719 114.0
HKD3_k127_6046449_9 Hydrogenase maturation protease - - - 0.00000000000001304 80.0
HKD3_k127_6049535_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.182e-235 735.0
HKD3_k127_6049535_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 2.113e-219 692.0
HKD3_k127_6049535_10 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000007077 103.0
HKD3_k127_6049535_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000008821 96.0
HKD3_k127_6049535_12 Protein of unknown function (DUF1573) - - - 0.000000000000001033 92.0
HKD3_k127_6049535_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000259 68.0
HKD3_k127_6049535_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.00005299 55.0
HKD3_k127_6049535_2 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 516.0
HKD3_k127_6049535_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 350.0
HKD3_k127_6049535_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002054 252.0
HKD3_k127_6049535_5 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001517 201.0
HKD3_k127_6049535_6 receptor K16092 - - 0.00000000000000000000000000000000000000000000001492 192.0
HKD3_k127_6049535_7 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000004287 155.0
HKD3_k127_6049535_8 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000001887 162.0
HKD3_k127_6049535_9 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.00000000000000000000000006857 123.0
HKD3_k127_6051064_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 627.0
HKD3_k127_6051064_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 554.0
HKD3_k127_6061802_0 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000000000000000000002901 214.0
HKD3_k127_6061802_1 protein secretion K20276 - - 0.0001647 54.0
HKD3_k127_6096617_0 peptidyl-tyrosine sulfation - - - 0.00000000001466 76.0
HKD3_k127_6107506_0 Prokaryotic cytochrome b561 - - - 0.0 1148.0
HKD3_k127_6107506_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 504.0
HKD3_k127_6107506_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 482.0
HKD3_k127_6107506_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 443.0
HKD3_k127_6107506_4 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000000001199 152.0
HKD3_k127_6107506_5 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000321 111.0
HKD3_k127_6107506_6 peptidase activity, acting on L-amino acid peptides - - - 0.00000000001201 69.0
HKD3_k127_6107593_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1194.0
HKD3_k127_6107593_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 316.0
HKD3_k127_6107593_2 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
HKD3_k127_6107593_3 Peptidase family M3 K01284,K01414 - 3.4.15.5,3.4.24.70 0.00000000000000000000000000000000000000000000000000002245 191.0
HKD3_k127_6107593_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000001316 121.0
HKD3_k127_6107593_5 peptidase U32 - - - 0.00000000000000000001644 95.0
HKD3_k127_6107593_6 - - - - 0.000000000000001365 89.0
HKD3_k127_6110284_0 Involved in the tonB-independent uptake of proteins - - - 9.499e-225 724.0
HKD3_k127_6110284_1 C4-dicarboxylate anaerobic carrier - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 406.0
HKD3_k127_6110284_2 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000008832 223.0
HKD3_k127_6117977_0 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 467.0
HKD3_k127_6117977_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 380.0
HKD3_k127_6117977_10 - - - - 0.0009159 48.0
HKD3_k127_6117977_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001153 251.0
HKD3_k127_6117977_3 mitochondrial electron transport, NADH to ubiquinone K10353 - 2.7.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000005812 255.0
HKD3_k127_6117977_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001556 244.0
HKD3_k127_6117977_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000003386 248.0
HKD3_k127_6117977_6 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000346 158.0
HKD3_k127_6117977_7 DNA mismatch repair protein MutT - - - 0.000000000000000000000000000000109 134.0
HKD3_k127_6117977_9 PFAM Tetratricopeptide repeat - - - 0.00005112 56.0
HKD3_k127_6137060_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003765 275.0
HKD3_k127_6137060_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000004653 268.0
HKD3_k127_6137060_10 - - - - 0.0005123 43.0
HKD3_k127_6137060_2 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004299 260.0
HKD3_k127_6137060_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000009626 135.0
HKD3_k127_6137060_5 Sporulation and spore germination - - - 0.0000000000000007425 87.0
HKD3_k127_6137060_6 lyase activity - - - 0.0000003904 61.0
HKD3_k127_6137060_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000009965 56.0
HKD3_k127_6164858_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 8.147e-285 905.0
HKD3_k127_6164858_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 547.0
HKD3_k127_6164858_2 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 361.0
HKD3_k127_6164858_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
HKD3_k127_6164858_4 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000009296 95.0
HKD3_k127_6164858_5 Acid phosphatase - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000001105 75.0
HKD3_k127_6164858_6 Iodothyronine deiodinase - - - 0.0000002594 63.0
HKD3_k127_6164858_7 Oar protein - - - 0.0000234 56.0
HKD3_k127_6180855_0 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000001814 102.0
HKD3_k127_6182817_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 410.0
HKD3_k127_6182817_1 CHRD domain - - - 0.0000004634 57.0
HKD3_k127_6184445_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 321.0
HKD3_k127_6184445_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000001543 62.0
HKD3_k127_6187952_0 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 503.0
HKD3_k127_6187952_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 321.0
HKD3_k127_6187952_2 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000001925 219.0
HKD3_k127_6187952_3 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.0000000000000000000000000000000000000000378 169.0
HKD3_k127_6187952_4 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000003396 142.0
HKD3_k127_6187952_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000003826 90.0
HKD3_k127_6200923_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 4.342e-199 646.0
HKD3_k127_6200923_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 348.0
HKD3_k127_6200923_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000006222 175.0
HKD3_k127_6200923_3 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.0000000000000001875 92.0
HKD3_k127_6217512_0 amine dehydrogenase activity - - - 7.174e-245 789.0
HKD3_k127_6217512_1 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 505.0
HKD3_k127_6217512_10 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000003359 199.0
HKD3_k127_6217512_11 DegV family - - - 0.00000000000000000000000000000000000000000000000001409 201.0
HKD3_k127_6217512_12 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.00000000000000000000000000000000000000000006207 166.0
HKD3_k127_6217512_13 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000008737 159.0
HKD3_k127_6217512_14 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000009934 138.0
HKD3_k127_6217512_15 Protease prsW family - - - 0.000000000000000000000000000000199 138.0
HKD3_k127_6217512_16 - - - - 0.0000000000000000000000000000002141 128.0
HKD3_k127_6217512_17 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000000001305 117.0
HKD3_k127_6217512_18 transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.000000000000000000005728 97.0
HKD3_k127_6217512_19 - - - - 0.00005327 53.0
HKD3_k127_6217512_2 PFAM Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 382.0
HKD3_k127_6217512_3 Oxidoreductase FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
HKD3_k127_6217512_4 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009672 274.0
HKD3_k127_6217512_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003112 255.0
HKD3_k127_6217512_6 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
HKD3_k127_6217512_7 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.00000000000000000000000000000000000000000000000000000000000001673 232.0
HKD3_k127_6217512_8 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD3_k127_6217512_9 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000001309 196.0
HKD3_k127_6256491_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 468.0
HKD3_k127_6256491_1 PFAM Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
HKD3_k127_6256491_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000005767 173.0
HKD3_k127_6256491_3 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000003224 154.0
HKD3_k127_6256491_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000004026 121.0
HKD3_k127_6256491_5 Protein of unknown function (DUF2723) - - - 0.0000000001355 75.0
HKD3_k127_6264911_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 386.0
HKD3_k127_6264911_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
HKD3_k127_6298961_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 393.0
HKD3_k127_6298961_1 PFAM ABC transporter related K01990 - - 0.000003484 53.0
HKD3_k127_6326337_0 Tricorn protease C1 domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000004448 226.0
HKD3_k127_6348758_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 379.0
HKD3_k127_6348758_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
HKD3_k127_6348758_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HKD3_k127_6348758_3 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007473 240.0
HKD3_k127_6348758_4 - - - - 0.0000000000000000000000000000000000000000004452 165.0
HKD3_k127_6348758_5 lyase activity - - - 0.0000000000000000000003756 112.0
HKD3_k127_6348758_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000008406 84.0
HKD3_k127_6348758_7 MacB-like periplasmic core domain K02004 - - 0.000000001028 62.0
HKD3_k127_6365126_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
HKD3_k127_6365126_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008031 263.0
HKD3_k127_6365126_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001366 183.0
HKD3_k127_6369972_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 309.0
HKD3_k127_6369972_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000006347 132.0
HKD3_k127_6369972_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000477 81.0
HKD3_k127_6373366_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 512.0
HKD3_k127_6373366_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 405.0
HKD3_k127_6373366_2 TIGRFAM 6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008746 269.0
HKD3_k127_6373366_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.000000000000000000000000000000000000000000000000000000005363 204.0
HKD3_k127_6373366_4 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000003873 55.0
HKD3_k127_6388738_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 312.0
HKD3_k127_6388738_1 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000001655 216.0
HKD3_k127_6388738_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000009776 203.0
HKD3_k127_6388738_3 lipase activity K15349 - - 0.0000000000000000000000000000000000000000009463 174.0
HKD3_k127_6388738_4 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000003084 156.0
HKD3_k127_6388738_5 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000001517 164.0
HKD3_k127_6388738_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000008648 84.0
HKD3_k127_6388738_7 antisigma factor binding - - - 0.00000000000000008439 85.0
HKD3_k127_6388738_8 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000002919 84.0
HKD3_k127_6391339_0 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000006128 228.0
HKD3_k127_6391339_1 translation release factor activity - - - 0.000000000000000000000000000000000000000000000883 180.0
HKD3_k127_6391339_2 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000003668 130.0
HKD3_k127_6391339_3 - - - - 0.0001138 53.0
HKD3_k127_6400032_0 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 302.0
HKD3_k127_6400032_1 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000051 213.0
HKD3_k127_6400032_2 4-amino-4-deoxy-L-arabinose transferase and related - - - 0.000002042 60.0
HKD3_k127_6472823_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 601.0
HKD3_k127_6472823_1 - - - - 0.00000000000000000000000000000000000000000000000000002247 208.0
HKD3_k127_6472823_2 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.00000000000000000000000002467 111.0
HKD3_k127_6472823_3 ABC-type cobalt transport system ATPase component K02006 - - 0.0000000000000000000002958 98.0
HKD3_k127_6506145_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.809e-233 739.0
HKD3_k127_6506145_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000001656 186.0
HKD3_k127_6506145_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000001476 168.0
HKD3_k127_6506145_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000009957 130.0
HKD3_k127_6506145_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000002507 116.0
HKD3_k127_6506145_5 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000002145 111.0
HKD3_k127_6506145_6 Zn peptidase - - - 0.000000000000005016 84.0
HKD3_k127_6506145_7 GGDEF domain - - - 0.000000000001661 75.0
HKD3_k127_6506145_8 TIGRFAM dihydropteroate synthase K00796 - 2.5.1.15 0.0001459 51.0
HKD3_k127_6544008_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 8.223e-238 751.0
HKD3_k127_6544008_1 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 612.0
HKD3_k127_6544008_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000166 88.0
HKD3_k127_6544008_11 Bacterial Ig-like domain - - - 0.0000000000000166 88.0
HKD3_k127_6544008_12 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000001424 84.0
HKD3_k127_6544008_13 Belongs to the UPF0434 family K09791 - - 0.000000000428 68.0
HKD3_k127_6544008_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001195 59.0
HKD3_k127_6544008_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 522.0
HKD3_k127_6544008_3 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 428.0
HKD3_k127_6544008_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 308.0
HKD3_k127_6544008_5 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000486 258.0
HKD3_k127_6544008_6 - - - - 0.00000000000000000000000000000000000000000000000000000000009475 227.0
HKD3_k127_6544008_7 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000007608 193.0
HKD3_k127_6544008_8 O-Antigen ligase K18814 - - 0.00000000000000000000000000002061 131.0
HKD3_k127_6544008_9 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.000000000000003003 87.0
HKD3_k127_6569590_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 564.0
HKD3_k127_6569590_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 432.0
HKD3_k127_6569590_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 322.0
HKD3_k127_6569590_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000008964 227.0
HKD3_k127_6569590_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000000000721 106.0
HKD3_k127_6577802_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000001073 194.0
HKD3_k127_6577802_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000774 165.0
HKD3_k127_6578369_0 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000005248 179.0
HKD3_k127_6578369_1 Surface antigen - - - 0.000000000000000000169 100.0
HKD3_k127_6624522_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.38e-247 783.0
HKD3_k127_6624522_1 hydrogenase large subunit K14126 - 1.8.98.5 5.237e-237 739.0
HKD3_k127_6624522_10 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000001052 208.0
HKD3_k127_6624522_11 Hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000005219 160.0
HKD3_k127_6624522_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000006789 141.0
HKD3_k127_6624522_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000002259 134.0
HKD3_k127_6624522_14 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000001839 106.0
HKD3_k127_6624522_15 Domain of unknown function (DUF2520) - - - 0.0000000000000001472 91.0
HKD3_k127_6624522_16 - - - - 0.0000003293 58.0
HKD3_k127_6624522_17 ABC transporter K01995,K01998 - - 0.000007489 54.0
HKD3_k127_6624522_2 Heat shock 70 kDa protein K04043 - - 1.434e-225 715.0
HKD3_k127_6624522_3 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 474.0
HKD3_k127_6624522_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 454.0
HKD3_k127_6624522_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
HKD3_k127_6624522_6 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001454 281.0
HKD3_k127_6624522_7 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006676 253.0
HKD3_k127_6624522_8 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
HKD3_k127_6624522_9 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000001265 245.0
HKD3_k127_6700002_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 405.0
HKD3_k127_6700002_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
HKD3_k127_6700002_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006106 243.0
HKD3_k127_6700002_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000001109 173.0
HKD3_k127_6700002_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000001019 160.0
HKD3_k127_6700002_5 NTPase K06928 - 3.6.1.15 0.0000000000000000000000000000000000006963 147.0
HKD3_k127_6700002_6 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000008921 96.0
HKD3_k127_6700002_7 SNARE associated Golgi protein - - - 0.0000001626 53.0
HKD3_k127_6767381_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 350.0
HKD3_k127_6767381_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 339.0
HKD3_k127_6767381_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
HKD3_k127_6767381_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HKD3_k127_6767381_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001276 276.0
HKD3_k127_6767381_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000001637 210.0
HKD3_k127_6767381_6 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000003165 154.0
HKD3_k127_6767381_7 Glycosyl transferase family 41 - - - 0.0000007715 62.0
HKD3_k127_6767381_8 Alpha beta - - - 0.00002147 56.0
HKD3_k127_6797388_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 9.487e-254 809.0
HKD3_k127_6797388_1 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 417.0
HKD3_k127_6797388_10 Protein conserved in bacteria - - - 0.00000000000000002307 91.0
HKD3_k127_6797388_11 GntR family transcriptional regulator K07979 - - 0.0009361 51.0
HKD3_k127_6797388_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 334.0
HKD3_k127_6797388_3 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 323.0
HKD3_k127_6797388_4 hydrolase of the alpha beta superfamily K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007636 273.0
HKD3_k127_6797388_5 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002641 230.0
HKD3_k127_6797388_6 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.00000000000000000000000000000000000000000000000000000000543 207.0
HKD3_k127_6797388_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000002204 124.0
HKD3_k127_6797388_8 Major Facilitator Superfamily - - - 0.00000000000000000005391 102.0
HKD3_k127_6797388_9 Poly(ADP-ribose) polymerase catalytic domain K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.000000000000000001356 100.0
HKD3_k127_68142_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 392.0
HKD3_k127_68142_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001467 264.0
HKD3_k127_68142_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000002037 175.0
HKD3_k127_68142_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004945 184.0
HKD3_k127_68142_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000007058 180.0
HKD3_k127_68142_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000001407 160.0
HKD3_k127_68142_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001448 155.0
HKD3_k127_68142_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000006662 139.0
HKD3_k127_68142_8 Could be involved in septation K06412 - - 0.000000000000000000006683 96.0
HKD3_k127_68142_9 Domain of unknown function (DUF4398) - - - 0.00002196 55.0
HKD3_k127_6837506_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 526.0
HKD3_k127_6837506_1 - - - - 0.00000002413 64.0
HKD3_k127_6850316_0 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 444.0
HKD3_k127_6850316_1 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000004188 243.0
HKD3_k127_6850316_2 - - - - 0.0000000000000000000000000000000000185 147.0
HKD3_k127_6851448_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 396.0
HKD3_k127_6851448_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009479 247.0
HKD3_k127_6851448_2 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000003858 234.0
HKD3_k127_6851448_3 domain, Protein - - - 0.00000000000000000000000000000000006006 154.0
HKD3_k127_6851448_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain - - - 0.000000000000000000000000000000009957 130.0
HKD3_k127_6851448_5 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000001204 128.0
HKD3_k127_6851448_6 Protein of unknown function, DUF547 - - - 0.00007066 54.0
HKD3_k127_6881284_0 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 409.0
HKD3_k127_6881284_1 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000002289 196.0
HKD3_k127_6926069_0 Peptidase M14, carboxypeptidase A - - - 3.815e-269 860.0
HKD3_k127_6926069_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000009799 86.0
HKD3_k127_6926069_2 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.00000003572 64.0
HKD3_k127_6932619_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000764 226.0
HKD3_k127_6932619_1 Efflux ABC transporter permease protein - - - 0.000000000000000000000000000000000000000000000007459 186.0
HKD3_k127_6970836_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 400.0
HKD3_k127_6970836_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000004127 234.0
HKD3_k127_6970836_2 ApaG domain K06195 - - 0.00000000000000000000000000000000000001937 167.0
HKD3_k127_6970836_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000001879 113.0
HKD3_k127_6970836_4 SMART phosphoesterase PA-phosphatase related - - - 0.00000000000000000000000001304 123.0
HKD3_k127_7091336_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000003538 185.0
HKD3_k127_7091336_1 - - - - 0.0000000000000000000003467 105.0
HKD3_k127_712468_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000008698 242.0
HKD3_k127_7257251_0 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000001979 114.0
HKD3_k127_7257251_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000001315 59.0
HKD3_k127_7257251_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00002835 52.0
HKD3_k127_7257373_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 5.299e-294 925.0
HKD3_k127_7257373_1 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 418.0
HKD3_k127_7257373_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000001711 201.0
HKD3_k127_7259335_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 339.0
HKD3_k127_7259335_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
HKD3_k127_7259335_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 244.0
HKD3_k127_7259335_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000005985 213.0
HKD3_k127_7259335_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002096 83.0
HKD3_k127_7261217_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 542.0
HKD3_k127_7261217_1 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 451.0
HKD3_k127_7261217_2 Doxx family K15977 - - 0.00000000000000000000000000000000000000000000006773 173.0
HKD3_k127_7261217_3 L-malate dehydrogenase activity - - - 0.0000000000000000000000000000000000000000003051 179.0
HKD3_k127_7261217_4 Transglycosylase associated protein - - - 0.0000000000000000000000000000007615 124.0
HKD3_k127_7262429_0 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 595.0
HKD3_k127_7262429_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 455.0
HKD3_k127_7262429_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 359.0
HKD3_k127_7262429_3 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 339.0
HKD3_k127_7262429_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
HKD3_k127_7262429_5 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000137 196.0
HKD3_k127_7262429_6 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000004044 180.0
HKD3_k127_7262429_7 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000007534 136.0
HKD3_k127_7262429_8 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000125 124.0
HKD3_k127_7268955_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 582.0
HKD3_k127_7268955_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 504.0
HKD3_k127_7268955_10 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000001604 237.0
HKD3_k127_7268955_11 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000007707 236.0
HKD3_k127_7268955_12 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000000000004152 190.0
HKD3_k127_7268955_13 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000001133 174.0
HKD3_k127_7268955_14 oxidase subunit K08738 - - 0.000000000000000000000000000000000000000000008236 177.0
HKD3_k127_7268955_15 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000001446 149.0
HKD3_k127_7268955_16 BMC K04027 - - 0.000000000000000000000000000000001797 132.0
HKD3_k127_7268955_17 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000004513 140.0
HKD3_k127_7268955_18 Ethanolamine utilisation protein EutN/carboxysome - - - 0.00000000000000000000000008011 109.0
HKD3_k127_7268955_19 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.0000000000000000000000001225 116.0
HKD3_k127_7268955_2 Aldehyde dehydrogenase (NAD) family protein K13922 - 1.2.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 467.0
HKD3_k127_7268955_20 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000002008 99.0
HKD3_k127_7268955_21 Bacterial membrane protein, YfhO - - - 0.0000000000000000000004057 113.0
HKD3_k127_7268955_22 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000005083 98.0
HKD3_k127_7268955_23 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000001331 98.0
HKD3_k127_7268955_24 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000001249 89.0
HKD3_k127_7268955_25 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000006605 54.0
HKD3_k127_7268955_26 Protein of unknown function (DUF4013) - - - 0.00001066 57.0
HKD3_k127_7268955_3 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 404.0
HKD3_k127_7268955_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 337.0
HKD3_k127_7268955_5 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 351.0
HKD3_k127_7268955_6 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003974 279.0
HKD3_k127_7268955_7 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
HKD3_k127_7268955_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 277.0
HKD3_k127_7268955_9 Cytochrome bd terminal oxidase subunit I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007667 261.0
HKD3_k127_7280263_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.001e-222 702.0
HKD3_k127_7280263_1 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 523.0
HKD3_k127_7335955_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.453e-225 709.0
HKD3_k127_7335955_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 567.0
HKD3_k127_7335955_10 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 428.0
HKD3_k127_7335955_11 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 437.0
HKD3_k127_7335955_12 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 423.0
HKD3_k127_7335955_13 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 395.0
HKD3_k127_7335955_14 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 386.0
HKD3_k127_7335955_15 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 365.0
HKD3_k127_7335955_16 PFAM HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 363.0
HKD3_k127_7335955_17 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 365.0
HKD3_k127_7335955_18 Pfam Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
HKD3_k127_7335955_19 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 362.0
HKD3_k127_7335955_2 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 487.0
HKD3_k127_7335955_20 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 365.0
HKD3_k127_7335955_21 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 341.0
HKD3_k127_7335955_22 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
HKD3_k127_7335955_23 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 336.0
HKD3_k127_7335955_24 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 351.0
HKD3_k127_7335955_25 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 333.0
HKD3_k127_7335955_26 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006845 318.0
HKD3_k127_7335955_27 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 327.0
HKD3_k127_7335955_28 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 319.0
HKD3_k127_7335955_29 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 300.0
HKD3_k127_7335955_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 458.0
HKD3_k127_7335955_30 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD3_k127_7335955_31 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
HKD3_k127_7335955_32 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 282.0
HKD3_k127_7335955_33 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 253.0
HKD3_k127_7335955_34 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007427 266.0
HKD3_k127_7335955_35 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HKD3_k127_7335955_36 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000009981 232.0
HKD3_k127_7335955_37 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001198 237.0
HKD3_k127_7335955_38 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000009648 224.0
HKD3_k127_7335955_39 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000006558 224.0
HKD3_k127_7335955_4 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 458.0
HKD3_k127_7335955_40 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000001576 213.0
HKD3_k127_7335955_41 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000003291 209.0
HKD3_k127_7335955_42 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000000000000000000000000000000000000000003539 216.0
HKD3_k127_7335955_43 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000006345 210.0
HKD3_k127_7335955_44 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000001501 208.0
HKD3_k127_7335955_45 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000001462 192.0
HKD3_k127_7335955_46 GAF domain - - - 0.00000000000000000000000000000000000000000000000004586 192.0
HKD3_k127_7335955_47 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000001377 192.0
HKD3_k127_7335955_48 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000003034 181.0
HKD3_k127_7335955_49 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000107 169.0
HKD3_k127_7335955_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 463.0
HKD3_k127_7335955_50 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000006736 177.0
HKD3_k127_7335955_51 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000001111 168.0
HKD3_k127_7335955_52 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000001381 165.0
HKD3_k127_7335955_53 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000006884 159.0
HKD3_k127_7335955_54 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000002716 149.0
HKD3_k127_7335955_55 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000002859 163.0
HKD3_k127_7335955_56 protein kinase activity - - - 0.0000000000000000000000000000000000008209 159.0
HKD3_k127_7335955_57 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000001688 144.0
HKD3_k127_7335955_59 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000002356 127.0
HKD3_k127_7335955_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 445.0
HKD3_k127_7335955_60 - - - - 0.000000000000000000000000003706 121.0
HKD3_k127_7335955_61 Belongs to the MraZ family K03925 - - 0.000000000000000000000000004256 118.0
HKD3_k127_7335955_62 YMGG-like Gly-zipper - - - 0.000000000000000000000000006119 119.0
HKD3_k127_7335955_63 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000001939 125.0
HKD3_k127_7335955_65 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000001728 106.0
HKD3_k127_7335955_66 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000006385 96.0
HKD3_k127_7335955_67 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000009491 95.0
HKD3_k127_7335955_69 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000005614 98.0
HKD3_k127_7335955_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 439.0
HKD3_k127_7335955_70 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000513 81.0
HKD3_k127_7335955_71 BatB protein K07114 - - 0.000000000000006296 89.0
HKD3_k127_7335955_72 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000006832 88.0
HKD3_k127_7335955_73 - - - - 0.000000002263 64.0
HKD3_k127_7335955_74 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000299 70.0
HKD3_k127_7335955_75 Essential cell division protein K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.00000007413 63.0
HKD3_k127_7335955_76 - - - - 0.0000009457 60.0
HKD3_k127_7335955_78 Oxygen tolerance - - - 0.000002559 60.0
HKD3_k127_7335955_79 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000005014 58.0
HKD3_k127_7335955_8 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 436.0
HKD3_k127_7335955_80 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000007923 59.0
HKD3_k127_7335955_81 TonB-dependent siderophore receptor K02014 - - 0.00006289 46.0
HKD3_k127_7335955_82 Multicopper oxidase - - - 0.00007199 55.0
HKD3_k127_7335955_83 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0006674 51.0
HKD3_k127_7335955_9 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 429.0
HKD3_k127_7342310_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000002548 248.0
HKD3_k127_7342310_1 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000006093 134.0
HKD3_k127_7342310_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000008653 89.0
HKD3_k127_7342310_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000002446 87.0
HKD3_k127_7391731_0 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001731 233.0
HKD3_k127_7391731_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000004117 173.0
HKD3_k127_7391731_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.0002535 46.0
HKD3_k127_7423010_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 446.0
HKD3_k127_7423010_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000002134 217.0
HKD3_k127_7423010_2 CotH kinase protein - - - 0.000004728 58.0
HKD3_k127_7423010_3 peptide catabolic process K01256 - 3.4.11.2 0.00002304 55.0
HKD3_k127_7434453_0 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000001237 235.0
HKD3_k127_7434453_2 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000001167 90.0
HKD3_k127_7434453_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000001079 76.0
HKD3_k127_7434453_4 - - - - 0.000001994 54.0
HKD3_k127_7453504_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 9.65e-254 799.0
HKD3_k127_7453504_1 PFAM glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 365.0
HKD3_k127_7453504_10 unfolded protein binding K06142 - - 0.000000002797 70.0
HKD3_k127_7453504_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 314.0
HKD3_k127_7453504_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001723 258.0
HKD3_k127_7453504_4 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000005573 207.0
HKD3_k127_7453504_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000001601 193.0
HKD3_k127_7453504_6 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000001663 183.0
HKD3_k127_7453504_7 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000004905 185.0
HKD3_k127_7453504_8 Glycosyl transferase, family 2 - - - 0.00000000000000000417 96.0
HKD3_k127_7453504_9 Glycosyl transferase K20444 - - 0.0000000000000001659 93.0
HKD3_k127_7459450_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.254e-205 649.0
HKD3_k127_7459450_1 Sodium:solute symporter family K14393 - - 0.000000000000000000000000008583 115.0
HKD3_k127_7469025_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 630.0
HKD3_k127_7469025_1 Phospholipase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 552.0
HKD3_k127_7469025_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000004238 173.0
HKD3_k127_7469025_11 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000822 168.0
HKD3_k127_7469025_12 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000001075 159.0
HKD3_k127_7469025_13 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000001567 165.0
HKD3_k127_7469025_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000001053 155.0
HKD3_k127_7469025_15 YsiA-like protein, C-terminal region K13770 - - 0.0000000000000000000000000000000000005001 148.0
HKD3_k127_7469025_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000002765 116.0
HKD3_k127_7469025_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000061 96.0
HKD3_k127_7469025_18 - - - - 0.0000004346 54.0
HKD3_k127_7469025_19 Domain of unknown function (DUF4440) - - - 0.0000008077 60.0
HKD3_k127_7469025_2 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 503.0
HKD3_k127_7469025_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 445.0
HKD3_k127_7469025_4 Amino-transferase class IV K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 366.0
HKD3_k127_7469025_5 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002246 293.0
HKD3_k127_7469025_6 Competence-damaged protein K03742,K03743 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000001838 265.0
HKD3_k127_7469025_7 Protein export membrane protein K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002238 271.0
HKD3_k127_7469025_8 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000001237 243.0
HKD3_k127_7469025_9 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000005428 182.0
HKD3_k127_7470127_0 AcrB/AcrD/AcrF family - - - 6.296e-286 894.0
HKD3_k127_7470127_1 - - - - 0.0000000000000000000008082 98.0
HKD3_k127_7470127_2 glyoxalase III activity - - - 0.000001155 57.0
HKD3_k127_7477267_0 von Willebrand factor, type A K07114 - - 1.555e-264 841.0
HKD3_k127_7477267_1 5' nucleotidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 597.0
HKD3_k127_7477267_10 - - - - 0.000000001316 71.0
HKD3_k127_7477267_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 513.0
HKD3_k127_7477267_3 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 489.0
HKD3_k127_7477267_4 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 468.0
HKD3_k127_7477267_5 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 312.0
HKD3_k127_7477267_6 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001699 259.0
HKD3_k127_7477267_7 Domain of Unknown Function with PDB structure (DUF3858) - - - 0.0000000000000000000000000002574 134.0
HKD3_k127_7477267_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000005027 108.0
HKD3_k127_7477267_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000001136 88.0
HKD3_k127_7477457_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 1.957e-303 942.0
HKD3_k127_7477457_1 MmgE/PrpD family K01720 - 4.2.1.79 8.921e-213 677.0
HKD3_k127_7477457_2 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009592 358.0
HKD3_k127_7477457_3 mRNA catabolic process K06950,K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006215 277.0
HKD3_k127_7477457_4 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000001477 205.0
HKD3_k127_7477457_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000001454 166.0
HKD3_k127_7477457_6 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000006225 93.0
HKD3_k127_7477457_7 Fibronectin type 3 domain - - - 0.0000000000000004244 90.0
HKD3_k127_7477457_8 TIGRFAM TonB K03832 - - 0.0000000000008099 79.0
HKD3_k127_7489097_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000005148 213.0
HKD3_k127_7489097_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000003521 175.0
HKD3_k127_7489097_2 transcriptional - - - 0.00000000002274 77.0
HKD3_k127_7495930_0 tRNA synthetases class II (D, K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000001808 168.0
HKD3_k127_7495930_1 - - - - 0.00000000564 65.0
HKD3_k127_7495930_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001867 65.0
HKD3_k127_7499337_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 582.0
HKD3_k127_7499337_1 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 563.0
HKD3_k127_7499337_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 477.0
HKD3_k127_7499337_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 448.0
HKD3_k127_7499337_4 PFAM Cys Met metabolism K01760,K01761 - 4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 451.0
HKD3_k127_7499337_5 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000003511 181.0
HKD3_k127_7499337_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000001224 135.0
HKD3_k127_7499337_7 COG1012 NAD-dependent aldehyde dehydrogenases K00131 - 1.2.1.9 0.0000000000000000000021 96.0
HKD3_k127_7499337_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000004098 96.0
HKD3_k127_7510554_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.101e-245 797.0
HKD3_k127_7510554_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 514.0
HKD3_k127_7510554_2 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 437.0
HKD3_k127_7510554_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 344.0
HKD3_k127_7510554_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004026 280.0
HKD3_k127_7510554_5 peptidase inhibitor activity - - - 0.000000000000000005185 100.0
HKD3_k127_7510554_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000002599 63.0
HKD3_k127_7530566_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.029e-205 656.0
HKD3_k127_7530566_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 318.0
HKD3_k127_7530566_2 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000002561 173.0
HKD3_k127_7530566_3 Pilus assembly protein, PilO K02664 - - 0.000000000000000000002533 105.0
HKD3_k127_7530566_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000006624 85.0
HKD3_k127_7530566_5 Fimbrial assembly protein (PilN) K02663 - - 0.00000000264 66.0
HKD3_k127_7543017_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 361.0
HKD3_k127_7543017_1 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000001301 143.0
HKD3_k127_7543017_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.0006376 53.0
HKD3_k127_7555100_0 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 562.0
HKD3_k127_7555100_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 309.0
HKD3_k127_7555100_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006609 266.0
HKD3_k127_7555100_3 isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000001702 232.0
HKD3_k127_7555100_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000003348 189.0
HKD3_k127_7555100_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000009703 86.0
HKD3_k127_7555100_6 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000002379 66.0
HKD3_k127_7566145_0 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 425.0
HKD3_k127_7566145_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
HKD3_k127_7566145_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000001439 191.0
HKD3_k127_7566145_3 acid phosphatase activity - - - 0.0000000000000000001131 101.0
HKD3_k127_7566145_4 Vacuole effluxer Atg22 like K06902 - - 0.00000000000001156 88.0
HKD3_k127_7606646_0 Beta-lactamase class C - - - 3.645e-263 822.0
HKD3_k127_7606646_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 463.0
HKD3_k127_7606646_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000001788 106.0
HKD3_k127_7606646_3 Cytochrome b/b6/petB K00127 - - 0.00000000000006905 81.0
HKD3_k127_7618174_0 Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 469.0
HKD3_k127_7618174_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 372.0
HKD3_k127_7618174_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 354.0
HKD3_k127_7618174_3 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000857 274.0
HKD3_k127_7618174_4 - - - - 0.00000000000000004045 84.0
HKD3_k127_7630631_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009512 596.0
HKD3_k127_7630631_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000002406 201.0
HKD3_k127_7630631_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000231 184.0
HKD3_k127_7630631_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000002068 104.0
HKD3_k127_7630631_4 - - - - 0.00000000000000000000001043 105.0
HKD3_k127_7630631_5 - - - - 0.00000003856 59.0
HKD3_k127_7637627_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 304.0
HKD3_k127_7637627_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 300.0
HKD3_k127_7637627_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000433 237.0
HKD3_k127_7637627_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000002531 170.0
HKD3_k127_7637627_4 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000004968 119.0
HKD3_k127_7637627_5 PQQ-like domain K17713 - - 0.000000000000914 78.0
HKD3_k127_7657217_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000001822 226.0
HKD3_k127_7657217_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000001955 189.0
HKD3_k127_7657217_2 PFAM glycosyl transferase family 2 K07011 - - 0.000000001107 65.0
HKD3_k127_7695052_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1045.0
HKD3_k127_7695052_1 Phosphotransferase enzyme family - - - 8.507e-281 897.0
HKD3_k127_7695052_10 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 388.0
HKD3_k127_7695052_11 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 385.0
HKD3_k127_7695052_12 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 346.0
HKD3_k127_7695052_13 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 339.0
HKD3_k127_7695052_14 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 328.0
HKD3_k127_7695052_15 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 322.0
HKD3_k127_7695052_16 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 301.0
HKD3_k127_7695052_17 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006537 287.0
HKD3_k127_7695052_19 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000711 260.0
HKD3_k127_7695052_2 Oligopeptide transporter OPT - - - 5.33e-247 782.0
HKD3_k127_7695052_20 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
HKD3_k127_7695052_21 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000008206 214.0
HKD3_k127_7695052_22 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
HKD3_k127_7695052_23 ABC transporter, ATP-binding protein K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000008658 201.0
HKD3_k127_7695052_24 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000005779 171.0
HKD3_k127_7695052_25 transmembrane transport - - - 0.00000000000000000000000000000000000000001344 164.0
HKD3_k127_7695052_26 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000005128 139.0
HKD3_k127_7695052_27 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000002024 146.0
HKD3_k127_7695052_28 hydrolase (HAD superfamily) K07026 - 3.1.3.70 0.00000000000000000000000000000003018 137.0
HKD3_k127_7695052_29 histidine kinase A domain protein - - - 0.000000000000000000000000000001272 132.0
HKD3_k127_7695052_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 631.0
HKD3_k127_7695052_30 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000004357 121.0
HKD3_k127_7695052_31 Tetratricopeptide repeat K08309 - - 0.000000000000000000000007733 119.0
HKD3_k127_7695052_32 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001726 86.0
HKD3_k127_7695052_33 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000002958 89.0
HKD3_k127_7695052_34 nuclear chromosome segregation - - - 0.0000000000002526 82.0
HKD3_k127_7695052_35 DivIVA domain K04074 - - 0.0000000003702 67.0
HKD3_k127_7695052_36 C4-type zinc ribbon domain K07164 - - 0.000000001543 68.0
HKD3_k127_7695052_38 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00005615 53.0
HKD3_k127_7695052_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 572.0
HKD3_k127_7695052_5 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 512.0
HKD3_k127_7695052_6 UvrD-like helicase C-terminal domain K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 518.0
HKD3_k127_7695052_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 503.0
HKD3_k127_7695052_8 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 489.0
HKD3_k127_7695052_9 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 394.0
HKD3_k127_7779485_0 Phosphoglycerol transferase family protein, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 492.0
HKD3_k127_7812240_0 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 610.0
HKD3_k127_7812240_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 614.0
HKD3_k127_7812240_10 Bacterial transferase hexapeptide (six repeats) K18234 - - 0.0000000000000000000000000000000000000000000004737 175.0
HKD3_k127_7812240_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001125 171.0
HKD3_k127_7812240_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000001399 137.0
HKD3_k127_7812240_13 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000034 116.0
HKD3_k127_7812240_14 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000002472 115.0
HKD3_k127_7812240_15 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000002542 114.0
HKD3_k127_7812240_16 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000477 111.0
HKD3_k127_7812240_17 Protein of unknown function (DUF2721) - - - 0.00000000000000005848 94.0
HKD3_k127_7812240_2 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 504.0
HKD3_k127_7812240_3 Alanine dehydrogenase/PNT, C-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 402.0
HKD3_k127_7812240_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 402.0
HKD3_k127_7812240_5 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 330.0
HKD3_k127_7812240_6 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000009344 274.0
HKD3_k127_7812240_7 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005658 256.0
HKD3_k127_7812240_8 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001124 232.0
HKD3_k127_7812240_9 deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000001011 214.0
HKD3_k127_7879888_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 634.0
HKD3_k127_7879888_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 496.0
HKD3_k127_7879888_10 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000008814 149.0
HKD3_k127_7879888_11 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000007214 142.0
HKD3_k127_7879888_12 Psort location CytoplasmicMembrane, score K07088 - - 0.000000000000000000000000000001351 135.0
HKD3_k127_7879888_13 - - - - 0.0000000000000000000001113 100.0
HKD3_k127_7879888_14 Transglycosylase associated protein - - - 0.000000000000000000001022 97.0
HKD3_k127_7879888_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000007684 78.0
HKD3_k127_7879888_2 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 425.0
HKD3_k127_7879888_3 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001698 249.0
HKD3_k127_7879888_4 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001477 249.0
HKD3_k127_7879888_5 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000002418 250.0
HKD3_k127_7879888_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000006254 198.0
HKD3_k127_7879888_7 PFAM DNA repair protein RadC K03630 - - 0.0000000000000000000000000000000000000000000000001101 186.0
HKD3_k127_7879888_8 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000007442 171.0
HKD3_k127_7879888_9 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000001163 160.0
HKD3_k127_7974955_0 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 512.0
HKD3_k127_7974955_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 399.0
HKD3_k127_7974955_2 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000000000009048 205.0
HKD3_k127_7974955_3 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000001252 179.0
HKD3_k127_7977635_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 415.0
HKD3_k127_7977635_1 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 316.0
HKD3_k127_7977635_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000000001445 86.0
HKD3_k127_7977635_11 Bacterial membrane protein, YfhO - - - 0.0000000000273 77.0
HKD3_k127_7977635_12 Protein of unknown function (DUF3891) - - - 0.0000000000652 72.0
HKD3_k127_7977635_13 general secretion pathway protein K02456 - - 0.000000002602 65.0
HKD3_k127_7977635_2 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 306.0
HKD3_k127_7977635_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 275.0
HKD3_k127_7977635_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
HKD3_k127_7977635_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005403 246.0
HKD3_k127_7977635_6 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000001325 171.0
HKD3_k127_7977635_7 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000001364 163.0
HKD3_k127_7977635_8 Receptor family ligand binding region - - - 0.000000000000000000000000000001197 135.0
HKD3_k127_7977635_9 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000003311 83.0
HKD3_k127_7979985_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 375.0
HKD3_k127_7979985_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002915 281.0
HKD3_k127_7979985_2 MacB-like periplasmic core domain K02004 - - 0.00000000005894 65.0
HKD3_k127_7994434_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 533.0
HKD3_k127_7994434_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
HKD3_k127_7994434_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000002401 131.0
HKD3_k127_7994434_3 Peptidase M56 - - - 0.000000006271 68.0
HKD3_k127_7994434_4 Surface antigen K07277 - - 0.0000006808 53.0
HKD3_k127_8043116_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 438.0
HKD3_k127_8043116_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
HKD3_k127_8043116_2 light absorption K06893 - - 0.000000000000000000000000000000002097 133.0
HKD3_k127_806164_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.548e-281 893.0
HKD3_k127_806164_1 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 2.225e-219 695.0
HKD3_k127_806164_10 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000001526 191.0
HKD3_k127_806164_11 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000002786 191.0
HKD3_k127_806164_12 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000007565 157.0
HKD3_k127_806164_13 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000001363 162.0
HKD3_k127_806164_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000002887 159.0
HKD3_k127_806164_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000005763 119.0
HKD3_k127_806164_16 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000001011 112.0
HKD3_k127_806164_17 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000004931 116.0
HKD3_k127_806164_18 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000007326 72.0
HKD3_k127_806164_19 outer membrane autotransporter barrel domain protein - - - 0.000000000004079 75.0
HKD3_k127_806164_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
HKD3_k127_806164_20 chaperone-mediated protein folding - - - 0.00000003991 67.0
HKD3_k127_806164_3 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 362.0
HKD3_k127_806164_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001877 282.0
HKD3_k127_806164_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000004267 270.0
HKD3_k127_806164_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000002014 262.0
HKD3_k127_806164_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000004177 249.0
HKD3_k127_806164_8 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000005367 235.0
HKD3_k127_806164_9 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000005179 227.0
HKD3_k127_81037_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 2.532e-219 709.0
HKD3_k127_81037_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 6.74e-203 648.0
HKD3_k127_81037_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000001736 202.0
HKD3_k127_81037_11 Pfam:TPM K08988 - - 0.000000000000000000000000000000000007609 156.0
HKD3_k127_81037_12 chain release factor K15034 - - 0.000000000000000000000000000000002148 134.0
HKD3_k127_81037_13 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000001937 132.0
HKD3_k127_81037_14 - - - - 0.00000000000000000000000000001974 120.0
HKD3_k127_81037_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001399 121.0
HKD3_k127_81037_16 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000001414 113.0
HKD3_k127_81037_17 Transcriptional regulator - - - 0.0000000000000000000000008516 110.0
HKD3_k127_81037_18 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000001413 101.0
HKD3_k127_81037_19 TIGRFAM TonB K03832 - - 0.00000000000000005724 89.0
HKD3_k127_81037_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 569.0
HKD3_k127_81037_20 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000006106 84.0
HKD3_k127_81037_21 - - - - 0.000000000000001583 89.0
HKD3_k127_81037_22 photosystem II stabilization - - - 0.000000000000004718 89.0
HKD3_k127_81037_23 acyl carrier protein - - - 0.000000001363 64.0
HKD3_k127_81037_24 - - - - 0.00005183 54.0
HKD3_k127_81037_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
HKD3_k127_81037_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 448.0
HKD3_k127_81037_5 PFAM ABC transporter related K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 313.0
HKD3_k127_81037_6 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000009828 224.0
HKD3_k127_81037_7 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000001585 210.0
HKD3_k127_81037_8 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000002063 216.0
HKD3_k127_81037_9 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
HKD3_k127_8129962_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 354.0
HKD3_k127_8173183_0 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003342 304.0
HKD3_k127_8173183_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000009226 143.0
HKD3_k127_8359337_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
HKD3_k127_8359337_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 452.0
HKD3_k127_8359337_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 413.0
HKD3_k127_8359337_3 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 311.0
HKD3_k127_8359337_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000328 250.0
HKD3_k127_8359337_5 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000007043 162.0
HKD3_k127_8359337_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000001415 119.0
HKD3_k127_8359337_7 Regulatory protein, FmdB - - - 0.000000000000000000000327 99.0
HKD3_k127_8359337_8 Domain of unknown function (DUF4388) - - - 0.0000000000003659 79.0
HKD3_k127_8359337_9 PFAM Outer membrane efflux protein - - - 0.000000003809 69.0
HKD3_k127_8460111_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 367.0
HKD3_k127_8460111_1 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 325.0
HKD3_k127_8460111_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000002799 53.0
HKD3_k127_8460942_0 AAA ATPase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 459.0
HKD3_k127_8460942_1 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 441.0
HKD3_k127_8460942_10 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000002305 136.0
HKD3_k127_8460942_11 - - - - 0.000000000000000000000000002701 113.0
HKD3_k127_8460942_12 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.00000000000000000000000534 109.0
HKD3_k127_8460942_13 - - - - 0.00000000000000000000001902 113.0
HKD3_k127_8460942_14 family UPF0066 K01628 - 4.1.2.17 0.000000000000000009664 91.0
HKD3_k127_8460942_15 - - - - 0.000000000000001215 86.0
HKD3_k127_8460942_16 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000001995 81.0
HKD3_k127_8460942_17 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000003854 78.0
HKD3_k127_8460942_18 Helix-turn-helix domain - - - 0.0000000006843 69.0
HKD3_k127_8460942_19 - - - - 0.00002731 55.0
HKD3_k127_8460942_2 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 323.0
HKD3_k127_8460942_3 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000006164 216.0
HKD3_k127_8460942_4 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000004968 197.0
HKD3_k127_8460942_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000008409 189.0
HKD3_k127_8460942_6 TIGRFAM maf protein K06287 - - 0.0000000000000000000000000000000000000007505 157.0
HKD3_k127_8460942_7 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000789 155.0
HKD3_k127_8460942_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000173 153.0
HKD3_k127_8460942_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000001373 140.0
HKD3_k127_8461185_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.219e-252 814.0
HKD3_k127_8461185_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000001587 204.0
HKD3_k127_8461185_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000007115 181.0
HKD3_k127_8461185_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000293 157.0
HKD3_k127_8467215_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 538.0
HKD3_k127_8467215_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 514.0
HKD3_k127_8467215_2 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 407.0
HKD3_k127_8467215_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 248.0
HKD3_k127_8467215_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002063 267.0
HKD3_k127_8467215_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000001588 190.0
HKD3_k127_8467215_6 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000004561 170.0
HKD3_k127_8468694_0 pyrophosphate-energized membrane proton pump K01507 - 3.6.1.1 2.891e-286 897.0
HKD3_k127_8468694_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.339e-265 848.0
HKD3_k127_8468694_10 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 400.0
HKD3_k127_8468694_11 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 353.0
HKD3_k127_8468694_12 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 333.0
HKD3_k127_8468694_13 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 332.0
HKD3_k127_8468694_14 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 319.0
HKD3_k127_8468694_15 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 311.0
HKD3_k127_8468694_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003652 294.0
HKD3_k127_8468694_17 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000005936 234.0
HKD3_k127_8468694_18 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000001333 218.0
HKD3_k127_8468694_19 Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000009323 174.0
HKD3_k127_8468694_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.661e-229 721.0
HKD3_k127_8468694_20 - - - - 0.0000000000000000000000000000000000000009887 158.0
HKD3_k127_8468694_21 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000004097 156.0
HKD3_k127_8468694_22 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000001519 122.0
HKD3_k127_8468694_23 protein conserved in bacteria - - - 0.0000000000000000000000000005205 117.0
HKD3_k127_8468694_24 Transport and Golgi organisation 2 - - - 0.000000000000000000000000002273 121.0
HKD3_k127_8468694_25 spore coat K01790 - 5.1.3.13 0.00000000000000000000000002657 115.0
HKD3_k127_8468694_26 NifU-like domain - - - 0.0000000000000000003807 94.0
HKD3_k127_8468694_27 ECF sigma factor K03088 - - 0.000000002931 65.0
HKD3_k127_8468694_28 - - - - 0.00000003348 62.0
HKD3_k127_8468694_29 Protein of unknown function (DUF2905) - - - 0.00000003593 61.0
HKD3_k127_8468694_3 carboxypeptidase - - - 1.046e-209 684.0
HKD3_k127_8468694_30 Modulates RecA activity K03565 - - 0.00000006013 61.0
HKD3_k127_8468694_31 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000001748 61.0
HKD3_k127_8468694_32 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000008277 61.0
HKD3_k127_8468694_33 Domain of unknown function (DUF4412) - - - 0.000002305 59.0
HKD3_k127_8468694_34 Acetyltransferase (GNAT) domain - - - 0.00003979 53.0
HKD3_k127_8468694_4 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 569.0
HKD3_k127_8468694_5 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 520.0
HKD3_k127_8468694_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
HKD3_k127_8468694_7 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 486.0
HKD3_k127_8468694_8 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 437.0
HKD3_k127_8468694_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 424.0
HKD3_k127_8475657_0 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 1.381e-205 666.0
HKD3_k127_8475657_1 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 591.0
HKD3_k127_8475657_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 510.0
HKD3_k127_8475657_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 402.0
HKD3_k127_8475657_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 291.0
HKD3_k127_8475657_5 COGs COG0790 FOG TPR repeat SEL1 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HKD3_k127_8475657_6 - - - - 0.0000000000000000000000000000001662 133.0
HKD3_k127_8475657_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.000000000000000000000001791 120.0
HKD3_k127_8475657_8 Belongs to the 'phage' integrase family - - - 0.00006612 46.0
HKD3_k127_8482162_0 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 507.0
HKD3_k127_8482162_1 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 468.0
HKD3_k127_8482162_2 of the major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 296.0
HKD3_k127_8482162_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000001476 176.0
HKD3_k127_8482162_4 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000001475 154.0
HKD3_k127_8511085_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000003884 228.0
HKD3_k127_8525234_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.659e-243 772.0
HKD3_k127_8525234_1 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 319.0
HKD3_k127_8525234_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 305.0
HKD3_k127_8525234_3 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000002328 166.0
HKD3_k127_8525234_4 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000004542 141.0
HKD3_k127_8525234_5 DRTGG domain - - - 0.00000000000000000000521 103.0
HKD3_k127_8525234_7 DRTGG domain - - - 0.00000004236 59.0
HKD3_k127_8550116_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.417e-247 775.0
HKD3_k127_8550116_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 459.0
HKD3_k127_8550116_10 Transcriptional regulator - - - 0.00005235 51.0
HKD3_k127_8550116_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 470.0
HKD3_k127_8550116_3 Heme copper-type cytochrome quinol oxidase, subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
HKD3_k127_8550116_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000006126 224.0
HKD3_k127_8550116_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000649 222.0
HKD3_k127_8550116_6 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000001695 175.0
HKD3_k127_8550116_7 Cytochrome oxidase assembly protein K02259,K03110 - - 0.000000000000000000000000000000000000001584 166.0
HKD3_k127_8550116_8 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000162 116.0
HKD3_k127_8550116_9 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000009633 89.0
HKD3_k127_8551367_0 Polysulphide reductase K00185 - - 2.217e-216 684.0
HKD3_k127_8551367_1 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 428.0
HKD3_k127_8551367_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 383.0
HKD3_k127_8551367_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 290.0
HKD3_k127_8551367_4 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HKD3_k127_8551367_5 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000002654 211.0
HKD3_k127_8551367_6 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000003671 139.0
HKD3_k127_8551367_7 - - - - 0.0000009537 55.0
HKD3_k127_8556870_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 612.0
HKD3_k127_8556870_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 489.0
HKD3_k127_8556870_2 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 317.0
HKD3_k127_8556870_3 Glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 298.0
HKD3_k127_8556870_4 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000001462 203.0
HKD3_k127_8556870_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000603 195.0
HKD3_k127_8561698_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 561.0
HKD3_k127_8561698_1 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 430.0
HKD3_k127_8561698_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 439.0
HKD3_k127_8561698_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 411.0
HKD3_k127_8599563_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000003988 212.0
HKD3_k127_8599563_1 FIST_C - - - 0.00002642 56.0
HKD3_k127_8628810_0 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000004039 130.0
HKD3_k127_8628810_1 Lipoate-protein ligase - - - 0.00000000000000000000000000009412 129.0
HKD3_k127_865208_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 391.0
HKD3_k127_865208_1 RDD family - - - 0.00000000000000000000000000000009322 130.0
HKD3_k127_8652100_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000001436 166.0
HKD3_k127_8652100_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000001794 145.0
HKD3_k127_8675053_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 356.0
HKD3_k127_8675053_1 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 333.0
HKD3_k127_8696808_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 455.0
HKD3_k127_8696808_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 296.0
HKD3_k127_8725396_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 510.0
HKD3_k127_8725396_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000006699 159.0
HKD3_k127_8725396_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000127 121.0
HKD3_k127_8725396_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002147 60.0
HKD3_k127_8739488_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 2.705e-317 989.0
HKD3_k127_87449_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004758 245.0
HKD3_k127_87449_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000006803 235.0
HKD3_k127_87449_2 Peptidase family M28 K19702 - 3.4.11.24 0.00000000000001401 88.0
HKD3_k127_8751087_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.679e-276 872.0
HKD3_k127_8751087_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.686e-271 856.0
HKD3_k127_8751087_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000005768 259.0
HKD3_k127_8751087_11 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
HKD3_k127_8751087_12 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000005316 213.0
HKD3_k127_8751087_13 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000247 205.0
HKD3_k127_8751087_14 helix_turn_helix gluconate operon transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000008503 192.0
HKD3_k127_8751087_15 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000002644 179.0
HKD3_k127_8751087_16 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000001783 151.0
HKD3_k127_8751087_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000009691 150.0
HKD3_k127_8751087_18 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000626 139.0
HKD3_k127_8751087_19 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001857 113.0
HKD3_k127_8751087_2 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 597.0
HKD3_k127_8751087_20 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000003843 96.0
HKD3_k127_8751087_21 Polymer-forming cytoskeletal - - - 0.00000000000003336 81.0
HKD3_k127_8751087_22 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000431 72.0
HKD3_k127_8751087_23 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000001002 79.0
HKD3_k127_8751087_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000004234 68.0
HKD3_k127_8751087_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 463.0
HKD3_k127_8751087_4 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 414.0
HKD3_k127_8751087_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 379.0
HKD3_k127_8751087_6 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 370.0
HKD3_k127_8751087_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
HKD3_k127_8751087_8 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
HKD3_k127_8751087_9 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005406 269.0
HKD3_k127_8754370_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 349.0
HKD3_k127_8754370_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000005739 235.0
HKD3_k127_8754370_2 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000008845 195.0
HKD3_k127_8754370_3 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002512 204.0
HKD3_k127_8754370_4 protein-disulfide reductase activity K04084 - 1.8.1.8 0.0000000000000000000000001681 115.0
HKD3_k127_8754370_5 Putative regulatory protein - - - 0.000000000000000000000001976 110.0
HKD3_k127_8754370_6 - - - - 0.0000000000000000003989 94.0
HKD3_k127_8787638_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.495e-244 764.0
HKD3_k127_8787638_1 SMART Elongator protein 3 MiaB NifB - - - 2.827e-238 762.0
HKD3_k127_8787638_10 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000003111 102.0
HKD3_k127_8787638_11 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000273 85.0
HKD3_k127_8787638_12 Glycosyltransferase family 87 - - - 0.0000000000002761 82.0
HKD3_k127_8787638_13 Methyltransferase domain - - - 0.0000000000009647 81.0
HKD3_k127_8787638_14 - - - - 0.0000000006483 72.0
HKD3_k127_8787638_15 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000005843 59.0
HKD3_k127_8787638_16 COGs COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000006107 59.0
HKD3_k127_8787638_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 476.0
HKD3_k127_8787638_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 336.0
HKD3_k127_8787638_4 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002159 289.0
HKD3_k127_8787638_5 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 265.0
HKD3_k127_8787638_6 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003669 261.0
HKD3_k127_8787638_7 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000003181 193.0
HKD3_k127_8787638_8 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000002788 171.0
HKD3_k127_8787638_9 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000964 116.0
HKD3_k127_8791049_0 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000001033 169.0
HKD3_k127_8791049_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000008701 166.0
HKD3_k127_8791049_2 - - - - 0.0000000000000000000000003836 108.0
HKD3_k127_8791049_3 - - - - 0.00000000000000000000006478 101.0
HKD3_k127_8791049_4 - - - - 0.000000000001156 67.0
HKD3_k127_8791049_5 cheY-homologous receiver domain - - - 0.000000000004607 72.0
HKD3_k127_8791049_6 histidine kinase A domain protein - - - 0.000000000007794 71.0
HKD3_k127_8791049_7 oxidation-reduction process - - - 0.000000382 52.0
HKD3_k127_8794819_0 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 557.0
HKD3_k127_8794819_1 Membrane dipeptidase (Peptidase family M19) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 464.0
HKD3_k127_8794819_2 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 402.0
HKD3_k127_8794819_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 335.0
HKD3_k127_8794819_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000672 278.0
HKD3_k127_8794819_5 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000644 239.0
HKD3_k127_8794819_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
HKD3_k127_8794819_7 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000002035 119.0
HKD3_k127_8794819_8 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000002005 120.0
HKD3_k127_8824339_0 aconitate hydratase K01681 - 4.2.1.3 6.187e-279 874.0
HKD3_k127_8824339_1 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 441.0
HKD3_k127_8824339_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000001659 225.0
HKD3_k127_8824339_3 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000000000000001441 134.0
HKD3_k127_8824339_4 Putative adhesin - - - 0.0000001398 63.0
HKD3_k127_8824339_5 Domain of unknown function (DUF4340) - - - 0.0000003601 61.0
HKD3_k127_8864054_0 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 496.0
HKD3_k127_8864054_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 372.0
HKD3_k127_8864054_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 381.0
HKD3_k127_8864054_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000002947 137.0
HKD3_k127_8885720_0 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 547.0
HKD3_k127_8885720_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 516.0
HKD3_k127_8885720_2 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HKD3_k127_8885720_3 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000003291 167.0
HKD3_k127_8885720_4 Helix-turn-helix domain - - - 0.000000000003171 76.0
HKD3_k127_8913097_0 glycosyltransferase 36 associated - - - 1.387e-220 710.0
HKD3_k127_8913097_1 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 291.0
HKD3_k127_8913097_2 hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000007973 192.0
HKD3_k127_8988375_0 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000005825 134.0
HKD3_k127_8988375_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003889 99.0
HKD3_k127_8988375_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000001366 85.0
HKD3_k127_9018887_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 7.765e-197 618.0
HKD3_k127_9018887_1 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 546.0
HKD3_k127_9018887_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 508.0
HKD3_k127_9018887_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
HKD3_k127_9018887_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000004862 220.0
HKD3_k127_9018887_5 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000003435 163.0
HKD3_k127_9018887_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000001035 137.0
HKD3_k127_9018887_7 Bacterial membrane protein, YfhO - - - 0.0000000007626 71.0
HKD3_k127_9096943_0 Major Facilitator Superfamily - - - 1.962e-199 632.0
HKD3_k127_9096943_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 499.0
HKD3_k127_9096943_10 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000001133 186.0
HKD3_k127_9096943_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000166 165.0
HKD3_k127_9096943_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002396 149.0
HKD3_k127_9096943_13 Iron-sulfur cluster insertion protein ErpA K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000001881 132.0
HKD3_k127_9096943_14 PDZ domain - - - 0.0000000000000004444 92.0
HKD3_k127_9096943_15 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000001414 81.0
HKD3_k127_9096943_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 398.0
HKD3_k127_9096943_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
HKD3_k127_9096943_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 342.0
HKD3_k127_9096943_5 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 331.0
HKD3_k127_9096943_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 311.0
HKD3_k127_9096943_7 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 299.0
HKD3_k127_9096943_8 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000001616 256.0
HKD3_k127_9096943_9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000006406 227.0
HKD3_k127_9110788_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 553.0
HKD3_k127_9110788_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 501.0
HKD3_k127_9110788_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007706 289.0
HKD3_k127_9110788_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000002417 151.0
HKD3_k127_9167183_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 529.0
HKD3_k127_9167183_1 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000005537 164.0
HKD3_k127_9215962_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 304.0
HKD3_k127_9215962_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
HKD3_k127_9215962_10 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000421 105.0
HKD3_k127_9215962_11 phosphotransferase related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000003093 108.0
HKD3_k127_9215962_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000002862 98.0
HKD3_k127_9215962_13 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000002156 77.0
HKD3_k127_9215962_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.00000000001711 66.0
HKD3_k127_9215962_15 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000004425 61.0
HKD3_k127_9215962_16 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0001059 54.0
HKD3_k127_9215962_17 PFAM response regulator receiver - - - 0.0009052 47.0
HKD3_k127_9215962_2 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003523 246.0
HKD3_k127_9215962_3 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
HKD3_k127_9215962_4 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000008401 198.0
HKD3_k127_9215962_5 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000186 181.0
HKD3_k127_9215962_6 positive regulation of growth rate - - - 0.000000000000000000000000000000000000000000003308 180.0
HKD3_k127_9215962_7 protein kinase activity - - - 0.00000000000000000000000000000000000042 157.0
HKD3_k127_9215962_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000008107 143.0
HKD3_k127_9215962_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000002006 117.0
HKD3_k127_9235818_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 454.0
HKD3_k127_9235818_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 425.0
HKD3_k127_9235818_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 374.0
HKD3_k127_9235818_3 4 iron, 4 sulfur cluster binding K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002239 251.0
HKD3_k127_9235818_4 Glycine cleavage H-protein - - - 0.0000000000000000000434 99.0
HKD3_k127_9235818_5 zinc metalloprotease whose natural substrate is K06974 - - 0.0000000000000000000614 96.0
HKD3_k127_9256227_0 amino acid K03294,K13868 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 421.0
HKD3_k127_9256227_2 Tetratricopeptide repeat - - - 0.000000000000000001246 97.0
HKD3_k127_9303384_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 519.0
HKD3_k127_9303384_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 435.0
HKD3_k127_9303384_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 419.0
HKD3_k127_9303384_3 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 297.0
HKD3_k127_9303384_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008955 300.0
HKD3_k127_9303384_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000009236 244.0
HKD3_k127_9303384_6 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000281 189.0
HKD3_k127_9303384_7 Universal stress protein - - - 0.000000000000000000000000000001512 132.0
HKD3_k127_9303384_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000002064 78.0
HKD3_k127_9404863_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.625e-198 650.0
HKD3_k127_9404863_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002487 280.0
HKD3_k127_9404863_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000002446 161.0
HKD3_k127_9404863_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000001143 152.0
HKD3_k127_9404863_4 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.00000000000000000000000000000001308 144.0
HKD3_k127_9404863_5 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000005334 115.0
HKD3_k127_9404863_6 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000001585 101.0
HKD3_k127_9404863_7 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000004354 81.0
HKD3_k127_9404863_8 glycoprotease K14742 - - 0.0000000000003113 79.0
HKD3_k127_9404863_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000844 64.0
HKD3_k127_9516732_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 587.0
HKD3_k127_9516732_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 590.0
HKD3_k127_9516732_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000003941 154.0
HKD3_k127_9516732_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000003924 153.0
HKD3_k127_9516732_12 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000006267 139.0
HKD3_k127_9516732_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000004553 114.0
HKD3_k127_9516732_14 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000007536 109.0
HKD3_k127_9516732_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005978 274.0
HKD3_k127_9516732_4 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000128 238.0
HKD3_k127_9516732_5 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000002366 207.0
HKD3_k127_9516732_6 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000003033 218.0
HKD3_k127_9516732_7 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000002808 198.0
HKD3_k127_9516732_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000001458 182.0
HKD3_k127_9516732_9 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000428 166.0