Overview

ID MAG01848
Name HKD3_bin.30
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Methyloligellaceae
Genus Methyloceanibacter
Species
Assembly information
Completeness (%) 59.79
Contamination (%) 1.59
GC content (%) 64.0
N50 (bp) 5,985
Genome size (bp) 1,422,684

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1515

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1001706_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 366.0
HKD3_k127_1001706_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
HKD3_k127_1001706_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000000000000001806 156.0
HKD3_k127_1001706_3 Ion channel - - - 0.00000000000000001024 83.0
HKD3_k127_1001706_4 GMC oxidoreductase K06151,K08261,K19813 - 1.1.5.9,1.1.99.21,1.1.99.3 0.00000000000000007992 81.0
HKD3_k127_1024213_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 337.0
HKD3_k127_1024213_1 Scaffold protein Nfu/NifU N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 286.0
HKD3_k127_1024213_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006177 283.0
HKD3_k127_1024213_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000005579 198.0
HKD3_k127_1024213_4 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000003342 151.0
HKD3_k127_1024213_5 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000001775 118.0
HKD3_k127_1024213_6 FR47-like protein K03789 - 2.3.1.128 0.0000000000000002981 88.0
HKD3_k127_102948_0 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 599.0
HKD3_k127_102948_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 567.0
HKD3_k127_102948_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 389.0
HKD3_k127_102948_3 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 301.0
HKD3_k127_102948_4 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000000000000000000000000000005506 231.0
HKD3_k127_102948_5 4-HFC-P synthase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000001208 204.0
HKD3_k127_102948_6 Amino acid kinase family - - - 0.00000000000000000000000000000000002779 149.0
HKD3_k127_102948_7 PFAM Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000002417 125.0
HKD3_k127_102948_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000001264 88.0
HKD3_k127_102948_9 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000001336 79.0
HKD3_k127_1038870_0 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 422.0
HKD3_k127_1038870_1 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
HKD3_k127_1038870_2 - - - - 0.000000000000000000000000000000000000003183 151.0
HKD3_k127_1038870_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000005995 109.0
HKD3_k127_1061725_0 Signal transduction histidine kinase K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 571.0
HKD3_k127_1061725_1 Sigma-54 interaction domain K13599 - - 0.000000000003912 66.0
HKD3_k127_1082099_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 394.0
HKD3_k127_1082099_1 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 345.0
HKD3_k127_1082099_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000123 213.0
HKD3_k127_1082099_3 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000005597 117.0
HKD3_k127_1170891_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000005406 223.0
HKD3_k127_1170891_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000001042 183.0
HKD3_k127_1170891_2 ABC-type nitrate sulfonate bicarbonate transport - - - 0.000000000000000000000000000000000000000005496 174.0
HKD3_k127_1170891_3 Haem-degrading - - - 0.00000000000000000000000000000001524 132.0
HKD3_k127_1186170_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 496.0
HKD3_k127_1186170_1 Dihydro-orotase-like K01465 - 3.5.2.3 0.000000000000006868 78.0
HKD3_k127_1203285_0 DEAD/H associated K03724 - - 3.036e-307 955.0
HKD3_k127_1203285_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 380.0
HKD3_k127_1203285_2 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005868 250.0
HKD3_k127_1203285_3 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000005009 202.0
HKD3_k127_1203810_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 577.0
HKD3_k127_1203810_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 458.0
HKD3_k127_1203810_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 393.0
HKD3_k127_1203810_3 PFAM Aminotransferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 333.0
HKD3_k127_1203810_4 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002326 244.0
HKD3_k127_1203810_5 - - - - 0.000000061 58.0
HKD3_k127_1203810_6 Predicted integral membrane protein (DUF2269) - - - 0.00001401 47.0
HKD3_k127_1248510_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001591 272.0
HKD3_k127_1248510_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
HKD3_k127_1248510_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000003662 218.0
HKD3_k127_1248510_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000005115 109.0
HKD3_k127_1281846_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.626e-247 772.0
HKD3_k127_1281846_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 589.0
HKD3_k127_1281846_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 291.0
HKD3_k127_1281846_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000004104 202.0
HKD3_k127_1281846_4 Disulfide bond formation protein DsbB - - - 0.0000000000000000000000000000000000000000000000000000005086 198.0
HKD3_k127_1281846_5 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000006112 149.0
HKD3_k127_1281846_6 Chorismate mutase, type II K04782 - 4.2.99.21 0.000000000000000000000000000000000009983 145.0
HKD3_k127_1281846_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000001147 130.0
HKD3_k127_1281846_8 - - - - 0.00001194 55.0
HKD3_k127_1281846_9 - - - - 0.0002798 45.0
HKD3_k127_1298552_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.391e-300 932.0
HKD3_k127_1298552_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 398.0
HKD3_k127_1298552_2 FAD FMN-containing dehydrogenases K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 379.0
HKD3_k127_1298552_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 335.0
HKD3_k127_1298552_4 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 286.0
HKD3_k127_1298552_5 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000000000000000000002085 207.0
HKD3_k127_1298552_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000000000000000000000005748 184.0
HKD3_k127_1298552_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000001648 120.0
HKD3_k127_1298552_8 Cytochrome P450 - - - 0.0000000000002421 76.0
HKD3_k127_1304522_0 RimK-like ATP-grasp domain K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 460.0
HKD3_k127_1304522_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000008071 231.0
HKD3_k127_1304522_2 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000001451 194.0
HKD3_k127_1304522_3 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000002311 173.0
HKD3_k127_1304522_4 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000004456 143.0
HKD3_k127_1304522_5 Sodium calcium exchanger membrane K07300 - - 0.000000000000001957 81.0
HKD3_k127_1304522_6 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000000002994 78.0
HKD3_k127_1315265_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.004e-304 955.0
HKD3_k127_1315265_1 Participates in both transcription termination and antitermination K02600 - - 7.851e-261 814.0
HKD3_k127_1315265_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000006911 153.0
HKD3_k127_1315265_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000515 102.0
HKD3_k127_1315265_12 PhoH-like protein K06217 - - 0.0001199 44.0
HKD3_k127_1315265_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 571.0
HKD3_k127_1315265_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 476.0
HKD3_k127_1315265_4 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 311.0
HKD3_k127_1315265_5 Putative methyltransferase K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
HKD3_k127_1315265_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000001311 194.0
HKD3_k127_1315265_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000001222 194.0
HKD3_k127_1315265_8 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000000000000000000000000000000003984 174.0
HKD3_k127_1315265_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000005845 149.0
HKD3_k127_1357714_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 617.0
HKD3_k127_1357714_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000002997 139.0
HKD3_k127_1371410_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 5.958e-314 975.0
HKD3_k127_1371410_1 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 269.0
HKD3_k127_1371410_2 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
HKD3_k127_1371410_3 histidine kinase A domain protein K07647,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001764 235.0
HKD3_k127_1371410_4 reductase K00001,K14446 - 1.1.1.1,1.3.1.85 0.00000000000000000000000000000000000000005379 153.0
HKD3_k127_1371410_5 HNH endonuclease - - - 0.0000000000000000000000000000000000002978 141.0
HKD3_k127_1371410_6 endonuclease III K01247 - 3.2.2.21 0.0000000000000000003724 94.0
HKD3_k127_1371410_7 endonuclease III K01247 - 3.2.2.21 0.00000000000002162 78.0
HKD3_k127_1371410_8 bacterioferritin-associated ferredoxin - - - 0.0000000000002434 72.0
HKD3_k127_1423276_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 362.0
HKD3_k127_1423276_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006418 276.0
HKD3_k127_1423276_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000002686 194.0
HKD3_k127_1423276_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000001445 164.0
HKD3_k127_1563996_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1084.0
HKD3_k127_1563996_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 363.0
HKD3_k127_1563996_2 membrane protein domain - - - 0.000000001665 59.0
HKD3_k127_1590439_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 1.154e-199 638.0
HKD3_k127_1590439_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 612.0
HKD3_k127_1590439_2 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 539.0
HKD3_k127_1590439_3 of ABC transporters with duplicated ATPase K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 353.0
HKD3_k127_1598390_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 415.0
HKD3_k127_1598390_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 348.0
HKD3_k127_1598390_2 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002258 288.0
HKD3_k127_1598390_4 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.0000000001263 66.0
HKD3_k127_1598390_5 membrane protein (DUF2078) K08982 - - 0.0000008977 53.0
HKD3_k127_1620847_0 Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 444.0
HKD3_k127_1620847_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
HKD3_k127_1620847_2 Cytochrome c - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000007045 135.0
HKD3_k127_1620847_3 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000001338 123.0
HKD3_k127_1620847_4 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0000000000001854 73.0
HKD3_k127_1620847_5 Protein of unknown function (DUF2735) - - - 0.0000000002884 63.0
HKD3_k127_1630589_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1322.0
HKD3_k127_1630589_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.995e-214 681.0
HKD3_k127_1630589_2 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 535.0
HKD3_k127_1630589_3 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 527.0
HKD3_k127_1630589_4 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 481.0
HKD3_k127_1630589_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000011 184.0
HKD3_k127_1637290_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 499.0
HKD3_k127_1637290_1 Protein of unknown function (DUF3754) - - - 0.000000000000000000000000000000000001287 145.0
HKD3_k127_1637290_2 Protein of unknown function (DUF3754) - - - 0.0000006466 55.0
HKD3_k127_1652060_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1041.0
HKD3_k127_1652060_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 287.0
HKD3_k127_1652060_2 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000003161 181.0
HKD3_k127_1657683_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 602.0
HKD3_k127_1657683_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000006899 112.0
HKD3_k127_1664731_0 Adenylylsulphate kinase K00955,K00956 - 2.7.1.25,2.7.7.4 7.419e-265 833.0
HKD3_k127_1664731_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 504.0
HKD3_k127_1664731_2 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 315.0
HKD3_k127_1664731_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
HKD3_k127_1664731_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002672 274.0
HKD3_k127_1664731_5 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.000000000000000000000000000000000000000000000000003469 184.0
HKD3_k127_1664731_6 NMT1-like family - - - 0.00000000000000000000000000005262 123.0
HKD3_k127_1664731_7 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000172 68.0
HKD3_k127_1679978_0 Domain of unknown function (DUF374) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 4.55e-198 637.0
HKD3_k127_1679978_1 ABC transporter transmembrane region K02021,K06147,K11085 - - 3.695e-197 633.0
HKD3_k127_1679978_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 604.0
HKD3_k127_1679978_3 Exonuclease VII, large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 549.0
HKD3_k127_1679978_4 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 359.0
HKD3_k127_1679978_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002125 283.0
HKD3_k127_1679978_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000002035 133.0
HKD3_k127_1679978_7 Domain of unknown function (DUF4170) - - - 0.0000000000000000000000000007615 115.0
HKD3_k127_1679978_8 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.00000000000000000000003578 101.0
HKD3_k127_1697937_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1105.0
HKD3_k127_1697937_1 Sulfate permease family K03321 - - 0.0000000000000000000000000000004446 125.0
HKD3_k127_1697937_2 Sulfate permease family K03321 - - 0.0000000000002225 74.0
HKD3_k127_1697937_3 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.00000000001052 66.0
HKD3_k127_1698959_0 Class II Aldolase and Adducin N-terminal domain - - - 1.102e-261 824.0
HKD3_k127_1698959_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 357.0
HKD3_k127_1698959_2 - - - - 0.0000009727 54.0
HKD3_k127_1703701_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 564.0
HKD3_k127_1706540_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 505.0
HKD3_k127_1706540_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 449.0
HKD3_k127_1706540_2 prohibitin homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 434.0
HKD3_k127_1706540_3 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 412.0
HKD3_k127_1706540_4 COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 368.0
HKD3_k127_1706540_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000006465 258.0
HKD3_k127_1706540_6 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000001983 136.0
HKD3_k127_1706540_7 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000001113 129.0
HKD3_k127_1706540_8 SOS response K14160 - - 0.00000000000000000002589 102.0
HKD3_k127_1706540_9 - - - - 0.000000000001084 76.0
HKD3_k127_1724863_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 545.0
HKD3_k127_1724863_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000002847 199.0
HKD3_k127_1724863_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000015 184.0
HKD3_k127_1724863_3 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000004874 148.0
HKD3_k127_1743645_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.839e-204 644.0
HKD3_k127_1743645_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 344.0
HKD3_k127_1743645_2 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 304.0
HKD3_k127_1743645_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000002413 173.0
HKD3_k127_1743645_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000005954 159.0
HKD3_k127_1743645_5 BolA-like protein - - - 0.00000000000000000000000000000002139 127.0
HKD3_k127_1743645_6 - - - - 0.00000000000000007048 91.0
HKD3_k127_1743645_7 Metal-binding integral membrane protein - - - 0.0000000000189 71.0
HKD3_k127_1764464_0 Glycolate oxidase subunit K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 1.587e-205 649.0
HKD3_k127_1764464_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 3.274e-198 629.0
HKD3_k127_1764464_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 498.0
HKD3_k127_1764464_3 FAD linked oxidase K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 403.0
HKD3_k127_1764464_4 cytochrome K08738 - - 0.000000000000000000000000003919 116.0
HKD3_k127_1815454_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.609e-206 651.0
HKD3_k127_1815454_1 Lipoprotein releasing system transmembrane protein K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 563.0
HKD3_k127_1815454_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 299.0
HKD3_k127_1815454_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
HKD3_k127_1815454_4 Protein of unknown function (DUF1467) - - - 0.000000000000000004418 86.0
HKD3_k127_1815454_5 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.00000000003867 63.0
HKD3_k127_1875583_0 Domain of unknown function DUF21 K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 533.0
HKD3_k127_1875583_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 428.0
HKD3_k127_1875583_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
HKD3_k127_1875583_3 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000007043 57.0
HKD3_k127_1894318_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 501.0
HKD3_k127_1894318_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 498.0
HKD3_k127_1894318_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 384.0
HKD3_k127_1894318_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000004012 100.0
HKD3_k127_1896711_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
HKD3_k127_1896711_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 343.0
HKD3_k127_1896711_2 pfam php K02347 - - 0.000000000000000000000000001151 113.0
HKD3_k127_19577_0 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 301.0
HKD3_k127_19577_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000007668 266.0
HKD3_k127_19577_2 Recombinase zinc beta ribbon domain K06400 - - 0.0001172 44.0
HKD3_k127_196320_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 504.0
HKD3_k127_196320_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768,K01769 - 4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 358.0
HKD3_k127_196320_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000001603 183.0
HKD3_k127_196320_3 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000006188 166.0
HKD3_k127_196320_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000001221 76.0
HKD3_k127_196858_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.244e-210 664.0
HKD3_k127_196858_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 489.0
HKD3_k127_196858_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000001792 211.0
HKD3_k127_196858_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 - 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000005465 203.0
HKD3_k127_196858_4 Thioesterase involved in non-ribosomal peptide biosynthesis K02170 - 3.1.1.85 0.0000000000000000000001186 104.0
HKD3_k127_2010108_0 Tetratricopeptide repeat K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 355.0
HKD3_k127_2010108_1 hydroxylase K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 342.0
HKD3_k127_2010108_2 peptidase S16 K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000003633 261.0
HKD3_k127_2010108_3 YbaK prolyl-tRNA synthetase associated K19055 - - 0.00000000000000000000000000000000000000000000000000007012 192.0
HKD3_k127_2010108_4 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000002859 100.0
HKD3_k127_2010108_6 - - - - 0.0000000008558 61.0
HKD3_k127_2020150_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 370.0
HKD3_k127_2020150_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 359.0
HKD3_k127_2020150_2 Thermostable hemolysin - - - 0.0000000000000000000000000000000000000000000002294 174.0
HKD3_k127_2064741_0 Cytochrome c-type biogenesis protein K02198 - - 6.334e-307 952.0
HKD3_k127_2064741_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 418.0
HKD3_k127_2064741_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 302.0
HKD3_k127_2064741_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000322 191.0
HKD3_k127_2064741_4 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000002768 177.0
HKD3_k127_2064741_5 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000006524 154.0
HKD3_k127_207024_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.374e-247 776.0
HKD3_k127_207024_1 PQ loop repeat K15383 - - 0.0000000000000000006871 88.0
HKD3_k127_2102540_0 Major Facilitator Superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 395.0
HKD3_k127_2102540_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000008257 198.0
HKD3_k127_2116078_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 5.573e-271 848.0
HKD3_k127_2116078_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006035 271.0
HKD3_k127_2116078_2 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000003279 166.0
HKD3_k127_2116078_3 ThiS family K03636 - - 0.00000000000000000000003065 100.0
HKD3_k127_213398_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.39e-202 647.0
HKD3_k127_213398_1 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
HKD3_k127_213398_2 - - - - 0.00000000000000009603 82.0
HKD3_k127_2183285_0 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
HKD3_k127_2183285_1 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000002012 235.0
HKD3_k127_2183285_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000002804 144.0
HKD3_k127_2235475_0 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 3.224e-238 742.0
HKD3_k127_2235475_1 RNA pseudouridylate synthase K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 446.0
HKD3_k127_2235475_2 ATP12 chaperone protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004189 273.0
HKD3_k127_2235475_3 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.00000000000000005641 86.0
HKD3_k127_2235475_4 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.0000000000000001487 91.0
HKD3_k127_2342444_0 ATPase AAA K03924 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 501.0
HKD3_k127_2342444_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000001784 188.0
HKD3_k127_2342444_2 protein conserved in bacteria K09986 - - 0.00000000000000000000000000000000000000000000006038 175.0
HKD3_k127_242403_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.146e-224 700.0
HKD3_k127_242403_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 462.0
HKD3_k127_242403_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 445.0
HKD3_k127_242403_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 359.0
HKD3_k127_242403_4 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000001886 233.0
HKD3_k127_242403_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000001406 216.0
HKD3_k127_242403_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000001271 165.0
HKD3_k127_242403_7 Pfam:DUF1049 - - - 0.0000000000000000000007317 98.0
HKD3_k127_2425528_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 2.661e-312 958.0
HKD3_k127_2425528_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 563.0
HKD3_k127_2425528_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 539.0
HKD3_k127_2425528_3 Penicillin-binding Protein K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 542.0
HKD3_k127_2425528_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 495.0
HKD3_k127_2425528_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 428.0
HKD3_k127_2425528_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 374.0
HKD3_k127_2425528_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 295.0
HKD3_k127_2425528_8 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000008128 208.0
HKD3_k127_2425528_9 secreted (Periplasmic) protein - - - 0.000000000000007223 80.0
HKD3_k127_2443786_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.633e-195 617.0
HKD3_k127_2443786_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 432.0
HKD3_k127_2443786_2 Septum formation initiator - - - 0.0000000000000004801 84.0
HKD3_k127_245991_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1013.0
HKD3_k127_245991_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.17e-205 646.0
HKD3_k127_245991_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 336.0
HKD3_k127_245991_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
HKD3_k127_2467843_0 D-isomer specific 2-hydroxyacid dehydrogenase K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 554.0
HKD3_k127_2467843_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 524.0
HKD3_k127_2467843_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038,K21977 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 514.0
HKD3_k127_2467843_3 UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 352.0
HKD3_k127_2467843_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000263 214.0
HKD3_k127_2467843_5 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000009174 179.0
HKD3_k127_2467843_6 Bacterial SH3 domain K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000159 190.0
HKD3_k127_2467843_7 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000001064 64.0
HKD3_k127_2467843_8 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000214 55.0
HKD3_k127_2468976_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1023.0
HKD3_k127_2468976_1 Histidine kinase K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 523.0
HKD3_k127_2468976_10 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000368 102.0
HKD3_k127_2468976_11 Universal stress protein family - - - 0.00000000000000000000001604 110.0
HKD3_k127_2468976_12 Cytochrome c - - - 0.0000000000000000005921 90.0
HKD3_k127_2468976_13 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000002273 78.0
HKD3_k127_2468976_15 Protein required for attachment to host cells - - - 0.000006058 51.0
HKD3_k127_2468976_16 Response regulator receiver - - - 0.00001837 53.0
HKD3_k127_2468976_17 PilZ domain - - - 0.00005348 53.0
HKD3_k127_2468976_18 Bacterial protein of unknown function (DUF883) - - - 0.0009052 47.0
HKD3_k127_2468976_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 492.0
HKD3_k127_2468976_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 445.0
HKD3_k127_2468976_4 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 351.0
HKD3_k127_2468976_5 hopanoid biosynthesis associated protein HpnK K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 339.0
HKD3_k127_2468976_6 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 328.0
HKD3_k127_2468976_7 response regulator K14987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
HKD3_k127_2468976_8 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003924 225.0
HKD3_k127_2468976_9 helix_turn_helix, cAMP Regulatory protein K01420,K15861 - - 0.000000000000000000000000000000000000000000000000003086 190.0
HKD3_k127_2475901_0 Histidine kinase K11527 - 2.7.13.3 2.421e-229 739.0
HKD3_k127_2475901_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.00000009259 56.0
HKD3_k127_2507922_0 YmdB-like protein K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 410.0
HKD3_k127_2507922_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 411.0
HKD3_k127_2507922_10 Domain of unknown function (DUF4164) - - - 0.000002079 55.0
HKD3_k127_2507922_2 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 349.0
HKD3_k127_2507922_3 inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 317.0
HKD3_k127_2507922_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 302.0
HKD3_k127_2507922_5 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004658 264.0
HKD3_k127_2507922_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000001507 129.0
HKD3_k127_2507922_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000002309 98.0
HKD3_k127_2507922_8 B-1 B cell differentiation - - - 0.0000000000000001236 86.0
HKD3_k127_2507922_9 TIR domain - - - 0.0000000000004529 75.0
HKD3_k127_2512588_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 476.0
HKD3_k127_2512588_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
HKD3_k127_2512588_2 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000003489 118.0
HKD3_k127_2512588_3 Mitochondrial fission ELM1 K07276 - - 0.0000004293 59.0
HKD3_k127_2545445_0 Sigma-54 interaction domain K13599 - - 1.276e-235 735.0
HKD3_k127_2545445_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 486.0
HKD3_k127_2545445_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000001985 154.0
HKD3_k127_2559617_0 FtsX-like permease family K02004 - - 2.033e-206 672.0
HKD3_k127_2559617_1 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 337.0
HKD3_k127_2559617_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004582 282.0
HKD3_k127_2559617_3 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000005113 218.0
HKD3_k127_2559617_4 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000001955 172.0
HKD3_k127_2559617_5 CDP-alcohol phosphatidyltransferase K00995 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5 0.000000000000000000000000000000000000001524 152.0
HKD3_k127_2559617_6 dienelactone hydrolase - - - 0.000000000000000000000000000000000003189 142.0
HKD3_k127_2559835_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 301.0
HKD3_k127_2559835_1 PFAM MaoC domain protein dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0022607,GO:0032787,GO:0042620,GO:0042621,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0046487,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.00000000000000000000000000000000000000000000002266 175.0
HKD3_k127_2572182_0 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 576.0
HKD3_k127_2572182_1 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 451.0
HKD3_k127_2572182_10 DNA repair protein MmcB-like - - - 0.00000000000000000000000000000000000007116 147.0
HKD3_k127_2572182_11 protein SCO1 SenC K07152 - - 0.000000000000000000889 87.0
HKD3_k127_2572182_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 407.0
HKD3_k127_2572182_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 342.0
HKD3_k127_2572182_4 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
HKD3_k127_2572182_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 327.0
HKD3_k127_2572182_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
HKD3_k127_2572182_7 response regulator K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001804 279.0
HKD3_k127_2572182_9 S-adenosylmethionine decarboxylase K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000001736 175.0
HKD3_k127_2583858_0 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000379 186.0
HKD3_k127_2583858_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000009123 145.0
HKD3_k127_2583858_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000492 118.0
HKD3_k127_2583858_3 GTP-binding protein TypA K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 0.0000000000000000000000006275 104.0
HKD3_k127_2607789_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1345.0
HKD3_k127_2607789_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000855 187.0
HKD3_k127_2640968_0 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 478.0
HKD3_k127_2640968_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 444.0
HKD3_k127_2640968_2 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000004972 179.0
HKD3_k127_2640968_3 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000002521 105.0
HKD3_k127_2640968_4 NNMT/PNMT/TEMT family - - - 0.00008775 46.0
HKD3_k127_2657075_0 IG-like fold at C-terminal of FixG, putative oxidoreductase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.389e-198 630.0
HKD3_k127_2657075_1 Belongs to the heme-copper respiratory oxidase family K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 407.0
HKD3_k127_2657075_2 cytochrome C K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 368.0
HKD3_k127_2657075_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 368.0
HKD3_k127_2657075_4 copper-translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 310.0
HKD3_k127_2657075_5 FixH - - - 0.00000000000000000001553 100.0
HKD3_k127_2657075_6 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000009301 63.0
HKD3_k127_2720153_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 5.8e-253 785.0
HKD3_k127_2720153_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.168e-194 613.0
HKD3_k127_2720153_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000002333 98.0
HKD3_k127_2720153_12 Domain of unknown function (DUF4212) - - - 0.0005536 46.0
HKD3_k127_2720153_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 578.0
HKD3_k127_2720153_3 Belongs to the EutC family K03736 - 4.3.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 385.0
HKD3_k127_2720153_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 325.0
HKD3_k127_2720153_5 Belongs to the UPF0262 family - - - 0.00000000000000000000000000000000000000000000000000000000001897 211.0
HKD3_k127_2720153_6 Low molecular weight phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000001899 198.0
HKD3_k127_2720153_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000005898 180.0
HKD3_k127_2720153_8 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000007967 162.0
HKD3_k127_2720153_9 Amino acid ABC transporter substrate-binding protein K02030 - - 0.0000000000000000000000000000000000003022 151.0
HKD3_k127_2721555_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 8.25e-219 686.0
HKD3_k127_2721555_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 301.0
HKD3_k127_2721555_2 - - - - 0.00000000000000000000000000000002449 132.0
HKD3_k127_2721555_3 PFAM peptidase C14, caspase catalytic subunit p20 - - - 0.0000000000000000000000463 100.0
HKD3_k127_2721555_4 PFAM peptidase C14, caspase catalytic subunit p20 - - - 0.0000000000000008222 84.0
HKD3_k127_2736669_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 539.0
HKD3_k127_2736669_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007507 268.0
HKD3_k127_2736669_2 invasion associated locus B - - - 0.00000000000000000000000000000000007472 141.0
HKD3_k127_2736669_3 HdeA/HdeB family K19778 - - 0.00002472 53.0
HKD3_k127_2736669_4 Autoinducer binding domain K18098,K19733 - - 0.000285 48.0
HKD3_k127_2790292_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 1.664e-260 812.0
HKD3_k127_2790292_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 503.0
HKD3_k127_2790292_10 Alpha/beta hydrolase family - - - 0.000000000000000000001903 99.0
HKD3_k127_2790292_11 GGDEF domain - - - 0.00004802 47.0
HKD3_k127_2790292_12 diguanylate cyclase - - - 0.00009549 48.0
HKD3_k127_2790292_2 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
HKD3_k127_2790292_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003006 276.0
HKD3_k127_2790292_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006757 262.0
HKD3_k127_2790292_5 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000001844 262.0
HKD3_k127_2790292_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000002923 241.0
HKD3_k127_2790292_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000004799 215.0
HKD3_k127_2790292_8 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000001143 206.0
HKD3_k127_2790292_9 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000481 160.0
HKD3_k127_2822636_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 398.0
HKD3_k127_2822636_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001187 246.0
HKD3_k127_2866444_0 MgsA AAA+ ATPase C terminal K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 606.0
HKD3_k127_2866444_1 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 500.0
HKD3_k127_2866444_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000003796 89.0
HKD3_k127_287645_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.416e-263 821.0
HKD3_k127_287645_1 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 5.428e-240 758.0
HKD3_k127_287645_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
HKD3_k127_287645_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000001693 148.0
HKD3_k127_288990_0 Thiol oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 612.0
HKD3_k127_288990_1 Imelysin K07338 - - 0.000000001674 62.0
HKD3_k127_2896542_0 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 304.0
HKD3_k127_2896542_1 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000005056 222.0
HKD3_k127_2896542_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000009081 128.0
HKD3_k127_2896542_3 Belongs to the SOS response-associated peptidase family - - - 0.0000002627 59.0
HKD3_k127_2896542_4 - - - - 0.0005772 48.0
HKD3_k127_293124_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 500.0
HKD3_k127_293124_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 479.0
HKD3_k127_293124_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000008407 151.0
HKD3_k127_293124_3 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001767 139.0
HKD3_k127_293124_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000002253 100.0
HKD3_k127_2939930_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1026.0
HKD3_k127_2939930_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 3.03e-290 910.0
HKD3_k127_2939930_2 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 2.246e-197 641.0
HKD3_k127_2939930_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001234 260.0
HKD3_k127_2939930_4 - - - - 0.0000000000000000000000000000000000000000000006728 170.0
HKD3_k127_2939930_5 Putative diguanylate phosphodiesterase - - - 0.0000001149 57.0
HKD3_k127_2939930_6 Putative diguanylate phosphodiesterase - - - 0.00002824 51.0
HKD3_k127_2995662_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.507e-273 857.0
HKD3_k127_2995662_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000002711 148.0
HKD3_k127_2995662_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000001623 53.0
HKD3_k127_3013917_0 Signal transduction histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 543.0
HKD3_k127_3013917_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 507.0
HKD3_k127_3013917_10 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000532 252.0
HKD3_k127_3013917_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001535 249.0
HKD3_k127_3013917_12 - - - - 0.00000000000000000000000000000000000000000000000000001642 204.0
HKD3_k127_3013917_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000000002351 173.0
HKD3_k127_3013917_14 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000001238 117.0
HKD3_k127_3013917_15 Dodecin K09165 - - 0.0000000000000000000000003901 107.0
HKD3_k127_3013917_16 Cupin - - - 0.0000000000000000000001071 97.0
HKD3_k127_3013917_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 384.0
HKD3_k127_3013917_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
HKD3_k127_3013917_4 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 332.0
HKD3_k127_3013917_5 Two component transcriptional regulator K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 314.0
HKD3_k127_3013917_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 301.0
HKD3_k127_3013917_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 278.0
HKD3_k127_3013917_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001789 265.0
HKD3_k127_3013917_9 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000239 261.0
HKD3_k127_3121473_0 Required for chromosome condensation and partitioning K03529 - - 6.014e-304 965.0
HKD3_k127_3121473_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 451.0
HKD3_k127_3121473_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000002621 137.0
HKD3_k127_3121473_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000004737 125.0
HKD3_k127_3121473_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000001249 119.0
HKD3_k127_3121473_13 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000006045 94.0
HKD3_k127_3121473_14 Stage II sporulation protein P (SpoIIP) K06385 - - 0.0003709 52.0
HKD3_k127_3121473_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 449.0
HKD3_k127_3121473_3 Diguanylate cyclase phosphodiesterase with PAS PAC K13245 - 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 337.0
HKD3_k127_3121473_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 332.0
HKD3_k127_3121473_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
HKD3_k127_3121473_6 RNase H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000003304 239.0
HKD3_k127_3121473_7 Peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000002837 207.0
HKD3_k127_3121473_8 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000000000000000002174 197.0
HKD3_k127_3121473_9 - - - - 0.0000000000000000000000000000000000000000000000002277 186.0
HKD3_k127_3170818_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 538.0
HKD3_k127_3170818_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001739 253.0
HKD3_k127_3170818_2 - - - - 0.000000000000000000000000002215 118.0
HKD3_k127_3198520_0 COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 299.0
HKD3_k127_3225281_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008551 394.0
HKD3_k127_3225281_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 354.0
HKD3_k127_3225281_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.00000000000000000000000000000001591 128.0
HKD3_k127_3225281_3 PFAM TPR repeat-containing protein - - - 0.0000000000001934 77.0
HKD3_k127_3225281_4 - - - - 0.00006125 48.0
HKD3_k127_3236711_0 Permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000001584 209.0
HKD3_k127_3236711_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000001384 108.0
HKD3_k127_3236711_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15584 - - 0.00000000000000003022 81.0
HKD3_k127_3236711_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000005937 54.0
HKD3_k127_3296884_0 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 381.0
HKD3_k127_3296884_1 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 368.0
HKD3_k127_3297502_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 7.071e-213 669.0
HKD3_k127_3297502_1 FAD linked oxidases, C-terminal domain K00004,K00102 GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 618.0
HKD3_k127_3297502_2 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000006174 243.0
HKD3_k127_3297502_3 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000003993 200.0
HKD3_k127_3302500_0 Two component transcriptional regulator, winged helix family K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 349.0
HKD3_k127_3302500_1 HAMP domain - - - 0.0000000000000000000000000000000000002458 149.0
HKD3_k127_3302500_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000001454 109.0
HKD3_k127_3312262_0 Domain of unknown function (DUF1974) K06445 - - 0.0 1050.0
HKD3_k127_3312262_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 488.0
HKD3_k127_3312262_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 490.0
HKD3_k127_3312262_3 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 472.0
HKD3_k127_3312262_4 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 411.0
HKD3_k127_3312262_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 393.0
HKD3_k127_3312262_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 314.0
HKD3_k127_3312262_7 - - - - 0.000000000000000000000000000002971 127.0
HKD3_k127_3312262_8 CDGSH-type zinc finger. Function unknown. - - - 0.00000000000000000000000000004244 119.0
HKD3_k127_3312262_9 - - - - 0.0000000000181 74.0
HKD3_k127_332271_0 Carbamoyl-phosphate synthase L chain ATP-binding K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 4.813e-228 716.0
HKD3_k127_332271_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 524.0
HKD3_k127_332271_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HKD3_k127_332271_3 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003681 256.0
HKD3_k127_332271_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000001048 98.0
HKD3_k127_3425060_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.734e-220 691.0
HKD3_k127_3425060_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003109 228.0
HKD3_k127_3425060_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000009061 212.0
HKD3_k127_3425060_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000001357 205.0
HKD3_k127_3425060_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000000000000002395 188.0
HKD3_k127_3426855_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1e-212 684.0
HKD3_k127_3426855_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000004515 254.0
HKD3_k127_3496601_0 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 535.0
HKD3_k127_3496601_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 420.0
HKD3_k127_3496601_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 411.0
HKD3_k127_3496601_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 338.0
HKD3_k127_3496601_4 Cys/Met metabolism PLP-dependent enzyme K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000005991 183.0
HKD3_k127_3496601_5 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000001273 125.0
HKD3_k127_3523917_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000005073 146.0
HKD3_k127_3523917_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000001312 144.0
HKD3_k127_3523917_2 Glyoxalase-like domain - - - 0.000000000000000001947 88.0
HKD3_k127_3523917_3 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000003707 78.0
HKD3_k127_3554121_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.702e-273 847.0
HKD3_k127_3554121_1 transport system, permease and ATPase K02471 - - 1.45e-198 632.0
HKD3_k127_3554121_2 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 359.0
HKD3_k127_3554121_3 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000002269 190.0
HKD3_k127_3554121_4 Chaperonin 10 Kd subunit K04078 - - 0.0000000000000000000000000000000000000000008363 159.0
HKD3_k127_3554121_5 Aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000374 110.0
HKD3_k127_356531_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 589.0
HKD3_k127_356531_1 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 384.0
HKD3_k127_356531_10 3'-5' exonuclease K03684 - 3.1.13.5 0.00000006132 53.0
HKD3_k127_356531_11 polygalacturonase activity - - - 0.0000002997 55.0
HKD3_k127_356531_12 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00001202 57.0
HKD3_k127_356531_2 Beta-lactamase K18988 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 305.0
HKD3_k127_356531_3 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.000000000000000000000000000000000000000000000000000000004126 208.0
HKD3_k127_356531_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000003999 205.0
HKD3_k127_356531_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000008873 201.0
HKD3_k127_356531_6 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000002318 133.0
HKD3_k127_356531_7 OstA-like protein K09774 - - 0.00000000000000000000000000005614 128.0
HKD3_k127_356531_8 Beta-lactamase K18988 - 3.4.16.4 0.00000000000000000000183 99.0
HKD3_k127_356531_9 Protein of unknown function (DUF1150) - - - 0.00000000000000008204 83.0
HKD3_k127_3638337_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
HKD3_k127_3638337_1 PFAM ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 368.0
HKD3_k127_3638337_2 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 331.0
HKD3_k127_3638337_3 ABC transporter K02074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 317.0
HKD3_k127_3638337_4 PFAM methyltransferase small - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
HKD3_k127_3638337_5 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000001251 224.0
HKD3_k127_3638337_6 Belongs to the Fur family K09823 - - 0.00000000000000000000000609 106.0
HKD3_k127_3642049_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 4.443e-248 772.0
HKD3_k127_3642049_1 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 269.0
HKD3_k127_3642049_2 Glutamate synthase central domain K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.00000000000000000000000002716 110.0
HKD3_k127_3654723_0 Proton-conducting membrane transporter - - - 6.891e-282 876.0
HKD3_k127_3654723_1 Proton-conducting membrane transporter K12141 - - 2.068e-239 747.0
HKD3_k127_3654723_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 4.448e-220 694.0
HKD3_k127_3654723_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 473.0
HKD3_k127_3654723_4 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 341.0
HKD3_k127_3654723_5 oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000985 104.0
HKD3_k127_3691743_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.843e-204 646.0
HKD3_k127_3691743_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.064e-195 621.0
HKD3_k127_3691743_2 Cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
HKD3_k127_3691743_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 339.0
HKD3_k127_3691743_4 NeuB family K01654,K05304,K18430 - 2.5.1.101,2.5.1.132,2.5.1.56,2.5.1.57 0.0000000000000000000004137 98.0
HKD3_k127_3716488_0 Alpha-2-Macroglobulin K06894 - - 0.0 2051.0
HKD3_k127_3716488_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 2.11e-265 843.0
HKD3_k127_3716488_2 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 482.0
HKD3_k127_3716488_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 467.0
HKD3_k127_3716488_4 ABC-type sulfate transport system, permease component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 407.0
HKD3_k127_3716488_5 ABC-type sulfate transport system, permease component K02046 - - 0.000000000000000000000000000000000007754 138.0
HKD3_k127_3716488_6 Beta-lactamase class C - - - 0.0000000000005498 69.0
HKD3_k127_3738197_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 527.0
HKD3_k127_3738197_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
HKD3_k127_3738197_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000002683 201.0
HKD3_k127_374140_0 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000007294 215.0
HKD3_k127_374140_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000006297 138.0
HKD3_k127_374140_2 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.000000009418 68.0
HKD3_k127_3742229_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 508.0
HKD3_k127_3742229_1 MotA/TolQ/ExbB proton channel family K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 301.0
HKD3_k127_3742229_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000001705 175.0
HKD3_k127_3742229_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000007761 142.0
HKD3_k127_3792357_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 1.604e-218 700.0
HKD3_k127_3792357_1 YcjX-like family, DUF463 K06918 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
HKD3_k127_3792357_2 Domain of unknown function (DUF697) K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
HKD3_k127_3792357_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000005177 247.0
HKD3_k127_3792357_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000004026 220.0
HKD3_k127_3792357_5 Flagellar biosynthesis protein, FliO - - - 0.000000000000004019 79.0
HKD3_k127_3792357_6 Papain family cysteine protease - - - 0.0006281 49.0
HKD3_k127_379776_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256,K15785 - 2.6.1.113,2.6.1.76 3.632e-262 811.0
HKD3_k127_379776_1 Belongs to the aldehyde dehydrogenase family - - - 2.309e-222 696.0
HKD3_k127_379776_2 -glutamine K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 334.0
HKD3_k127_379776_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000792 261.0
HKD3_k127_379776_4 Glutamine synthetase, catalytic domain K01915 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 0.000000000000000000000000000001984 121.0
HKD3_k127_379776_5 Amino acid permease K03294,K16238 - - 0.00000000000000007292 83.0
HKD3_k127_379776_6 Amino acid permease K03294,K16238 - - 0.0000000000001069 71.0
HKD3_k127_3847628_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 393.0
HKD3_k127_3847628_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 322.0
HKD3_k127_3847628_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000005251 216.0
HKD3_k127_3847628_3 Aldo/keto reductase family - - - 0.0000000000000158 73.0
HKD3_k127_3847628_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000203 56.0
HKD3_k127_3854889_0 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 480.0
HKD3_k127_3854889_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 416.0
HKD3_k127_3854889_2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 312.0
HKD3_k127_3854889_3 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000000000002123 186.0
HKD3_k127_3854889_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000009594 99.0
HKD3_k127_3933061_0 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 300.0
HKD3_k127_3933061_1 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000009023 176.0
HKD3_k127_3933061_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000002291 138.0
HKD3_k127_3933061_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000002936 113.0
HKD3_k127_3990531_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1143.0
HKD3_k127_3990531_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 5.259e-255 804.0
HKD3_k127_3990531_2 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000176 80.0
HKD3_k127_39995_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 4.764e-206 654.0
HKD3_k127_39995_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 565.0
HKD3_k127_39995_2 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001506 283.0
HKD3_k127_39995_3 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000004958 184.0
HKD3_k127_39995_4 - - - - 0.000000000003173 72.0
HKD3_k127_400548_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.041e-273 857.0
HKD3_k127_400548_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000153 269.0
HKD3_k127_4012320_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 537.0
HKD3_k127_4012320_1 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 471.0
HKD3_k127_4012320_2 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000001218 158.0
HKD3_k127_4015616_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 565.0
HKD3_k127_4015616_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 437.0
HKD3_k127_4015616_2 Protein of unknown function (DUF2865) - - - 0.000000000000000000000000003572 119.0
HKD3_k127_4021659_0 COG0174 Glutamine synthetase K01915 - 6.3.1.2 3.335e-247 767.0
HKD3_k127_4021659_1 -glutamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 429.0
HKD3_k127_4021659_2 COG0070 Glutamate synthase domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
HKD3_k127_4021659_3 Conserved region in glutamate synthase K22083 - 2.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
HKD3_k127_4127931_0 Histidine kinase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 597.0
HKD3_k127_4127931_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 437.0
HKD3_k127_4127931_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000006436 157.0
HKD3_k127_418284_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.009e-220 688.0
HKD3_k127_4204779_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 400.0
HKD3_k127_4204779_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000007087 166.0
HKD3_k127_4237170_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 544.0
HKD3_k127_4237170_1 PQQ-like domain K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 426.0
HKD3_k127_4237170_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
HKD3_k127_4237170_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000004495 205.0
HKD3_k127_4237170_4 DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000004072 196.0
HKD3_k127_4237170_5 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000007274 168.0
HKD3_k127_4237170_6 CorA-like Mg2+ transporter protein K16074 - - 0.00000000000000001718 85.0
HKD3_k127_4264611_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 7.933e-219 685.0
HKD3_k127_4264611_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008754 276.0
HKD3_k127_4264611_2 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000006272 186.0
HKD3_k127_4264611_3 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000001862 142.0
HKD3_k127_4274060_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 3.591e-206 647.0
HKD3_k127_4274060_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 611.0
HKD3_k127_4274060_10 Protein of unknown function (DUF1345) - - - 0.0000000000000000000000000000000000000000001548 170.0
HKD3_k127_4274060_11 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000003919 116.0
HKD3_k127_4274060_12 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000587 103.0
HKD3_k127_4274060_13 Protein of unknown function (DUF429) - - - 0.000000000000000000003328 101.0
HKD3_k127_4274060_14 GGDEF domain - - - 0.00000000001397 69.0
HKD3_k127_4274060_15 Putative diguanylate phosphodiesterase - - - 0.00000000001454 68.0
HKD3_k127_4274060_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 503.0
HKD3_k127_4274060_3 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 487.0
HKD3_k127_4274060_4 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 307.0
HKD3_k127_4274060_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 289.0
HKD3_k127_4274060_6 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000154 289.0
HKD3_k127_4274060_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000003888 226.0
HKD3_k127_4274060_8 Transglycosylase K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
HKD3_k127_4274060_9 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000007475 200.0
HKD3_k127_434348_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 534.0
HKD3_k127_434348_1 MafB19-like deaminase - - - 0.00000000000000008774 87.0
HKD3_k127_434348_2 MafB19-like deaminase - - - 0.0000000000000003087 82.0
HKD3_k127_438963_0 Aminotransferase K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 1.048e-209 657.0
HKD3_k127_438963_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 534.0
HKD3_k127_438963_2 Fructose-1,6-bisphosphatase K02446,K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 416.0
HKD3_k127_438963_3 exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000001919 252.0
HKD3_k127_4426913_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 386.0
HKD3_k127_4426913_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 296.0
HKD3_k127_4426913_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
HKD3_k127_4426913_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000397 207.0
HKD3_k127_4426913_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000006707 152.0
HKD3_k127_453444_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 344.0
HKD3_k127_453444_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000002461 161.0
HKD3_k127_453444_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000005533 131.0
HKD3_k127_4566294_0 COG0841 Cation multidrug efflux pump - - - 0.0 1363.0
HKD3_k127_4566294_1 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
HKD3_k127_4566294_2 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000001168 200.0
HKD3_k127_4566294_3 A circularly permuted ATPgrasp - - - 0.00000000000000000006541 92.0
HKD3_k127_4614117_0 Glycine cleavage T-protein C-terminal barrel domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.0 1276.0
HKD3_k127_4614117_1 Belongs to the glutamate synthase family K22083 - 2.1.1.21 9.097e-244 767.0
HKD3_k127_4614117_2 FAD dependent oxidoreductase K00303,K22084 - 1.5.3.1,1.5.99.5 5.495e-228 713.0
HKD3_k127_4614117_3 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 407.0
HKD3_k127_4614117_4 helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 398.0
HKD3_k127_4614117_5 GXGXG motif K22082 - 2.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 349.0
HKD3_k127_4614117_6 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 290.0
HKD3_k127_4614117_7 Glutamine synthetase, catalytic domain K01915,K01949 - 6.3.1.2,6.3.4.12 0.00000000000000000000000000000000000001051 147.0
HKD3_k127_4614117_8 Sarcosine oxidase, delta subunit K00304,K22085 - 1.5.3.1,1.5.99.5 0.000000000000000000000000000003371 123.0
HKD3_k127_461524_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000001051 219.0
HKD3_k127_461524_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000005779 158.0
HKD3_k127_461524_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000003195 144.0
HKD3_k127_4630677_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.926e-209 655.0
HKD3_k127_4630677_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 572.0
HKD3_k127_4630677_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 394.0
HKD3_k127_4630677_3 DnaJ C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 370.0
HKD3_k127_4630677_4 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000003706 105.0
HKD3_k127_4630677_5 Protein of unknown function (DUF2905) - - - 0.00000004277 57.0
HKD3_k127_4635802_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 1.008e-229 726.0
HKD3_k127_4635802_1 AMP-binding enzyme K00666 - - 1.059e-223 707.0
HKD3_k127_4635802_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 578.0
HKD3_k127_4635802_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001204 244.0
HKD3_k127_4635802_4 Permease family K06901 - - 0.000000000000000000000000000000007444 134.0
HKD3_k127_4663187_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 374.0
HKD3_k127_4663187_1 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001195 284.0
HKD3_k127_4663187_2 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001033 194.0
HKD3_k127_4663187_3 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K00087,K03518,K07302,K11177 - 1.17.1.4,1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000006959 179.0
HKD3_k127_4663187_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000002259 154.0
HKD3_k127_4804588_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 3.14e-305 942.0
HKD3_k127_4804588_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 554.0
HKD3_k127_4833563_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 363.0
HKD3_k127_4833563_1 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD3_k127_4865695_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 259.0
HKD3_k127_4865695_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000001879 246.0
HKD3_k127_4865695_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000006744 231.0
HKD3_k127_4865695_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000004305 164.0
HKD3_k127_4865695_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000355 116.0
HKD3_k127_4865695_5 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005489 105.0
HKD3_k127_4871361_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 2.229e-236 744.0
HKD3_k127_4871361_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 439.0
HKD3_k127_4871361_2 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000006044 222.0
HKD3_k127_4871361_3 Copper chaperone PCu(A)C K09796 - - 0.00000000001261 65.0
HKD3_k127_4871361_4 Copper resistance protein D K07245 - - 0.00000003026 59.0
HKD3_k127_4871361_5 copper resistance protein K07245 - - 0.0003438 51.0
HKD3_k127_4876702_0 Rod shape-determining protein (MreB) K03569 - - 0.00000000000000000000000000000000000000000000000000000000004431 210.0
HKD3_k127_4876702_1 shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000000000000000001159 205.0
HKD3_k127_497217_0 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 314.0
HKD3_k127_497217_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000001716 225.0
HKD3_k127_497217_2 - - - - 0.00000001317 64.0
HKD3_k127_4983303_0 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 416.0
HKD3_k127_4983303_1 Dihydrodipicolinate reductase, C-terminus K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 359.0
HKD3_k127_4983303_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 296.0
HKD3_k127_4983303_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 293.0
HKD3_k127_4983303_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
HKD3_k127_4983303_5 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.0000000000000000000000000000000000000000000000000000003393 200.0
HKD3_k127_4983303_6 Integral membrane protein (DUF2244) - - - 0.00000000000000000000000000000000000000000002016 166.0
HKD3_k127_4983303_7 Putative diguanylate phosphodiesterase - - - 0.00000000000003458 83.0
HKD3_k127_5018549_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 343.0
HKD3_k127_5018549_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
HKD3_k127_5018549_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
HKD3_k127_5018549_3 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.0000000007156 62.0
HKD3_k127_5023808_0 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 389.0
HKD3_k127_5023808_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000365 283.0
HKD3_k127_5023808_2 phosphohistidine phosphatase, SixA - - - 0.000000000000000000000000000000000000000000000000000000002375 221.0
HKD3_k127_5023808_3 transport system, permease and ATPase K02471 - - 0.000000000000000000000000000001722 123.0
HKD3_k127_5033685_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 599.0
HKD3_k127_5033685_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 322.0
HKD3_k127_5035510_0 Fumarase C C-terminus K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 544.0
HKD3_k127_5035510_1 protein histidine kinase activity K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000001928 147.0
HKD3_k127_505131_0 Serine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 530.0
HKD3_k127_505131_1 PFAM regulatory protein LysR K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 322.0
HKD3_k127_505131_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000001435 244.0
HKD3_k127_505131_3 - - - - 0.0005135 50.0
HKD3_k127_5112755_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 497.0
HKD3_k127_5112755_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 485.0
HKD3_k127_5112755_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000005791 176.0
HKD3_k127_5112755_3 Protein of unknown function - - - 0.00003329 51.0
HKD3_k127_5125225_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.258e-205 656.0
HKD3_k127_5125225_1 - - - - 0.00000000000000000006315 94.0
HKD3_k127_5125225_2 Protein of unknown function (DUF3311) - - - 0.0000000001099 66.0
HKD3_k127_5127978_0 Alpha beta hydrolase fold K01048 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 334.0
HKD3_k127_5127978_1 PFAM Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
HKD3_k127_5127978_2 TIGRFAM outer membrane autotransporter barrel domain - - - 0.00003865 49.0
HKD3_k127_5168618_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 419.0
HKD3_k127_5168618_1 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 323.0
HKD3_k127_5168618_2 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 316.0
HKD3_k127_5168618_3 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 283.0
HKD3_k127_5168618_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000009984 192.0
HKD3_k127_5168618_5 COG0471 Di- and tricarboxylate transporters - - - 0.000000000000000000000000000000000000000000000007011 179.0
HKD3_k127_5168618_6 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000004408 172.0
HKD3_k127_5168618_7 TrkA-C domain - - - 0.000000000000002753 82.0
HKD3_k127_5176942_0 Flavodoxin-like fold K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 289.0
HKD3_k127_5176942_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000961 262.0
HKD3_k127_5176942_2 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001618 256.0
HKD3_k127_5176942_4 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000008478 185.0
HKD3_k127_5176942_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002051 162.0
HKD3_k127_5176942_6 membrane - - - 0.00000000000000000000002162 101.0
HKD3_k127_5176942_7 - - - - 0.000000000000000000001009 102.0
HKD3_k127_5176942_8 - - - - 0.0000000000007676 70.0
HKD3_k127_5176942_9 - - - - 0.00000008851 56.0
HKD3_k127_5188640_0 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 1.584e-210 668.0
HKD3_k127_5188640_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 489.0
HKD3_k127_5188640_2 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000001961 209.0
HKD3_k127_5199227_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.979e-264 827.0
HKD3_k127_5199227_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 484.0
HKD3_k127_5199227_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 482.0
HKD3_k127_5199227_3 Fumarylacetoacetate (FAA) hydrolase family K16856 - 4.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 358.0
HKD3_k127_5199227_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 328.0
HKD3_k127_5199227_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 316.0
HKD3_k127_5199227_6 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 289.0
HKD3_k127_5199227_7 Protein of unknown function (DUF2283) - - - 0.00000000000000000000000000000403 120.0
HKD3_k127_5199227_8 - - - - 0.00000000000000000000000000319 117.0
HKD3_k127_5199227_9 - - - - 0.0000000000000003992 79.0
HKD3_k127_5242508_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.912e-222 692.0
HKD3_k127_5242508_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 386.0
HKD3_k127_5242508_2 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000385 190.0
HKD3_k127_5242508_3 Asparagine synthase K01953 - 6.3.5.4 0.000002986 50.0
HKD3_k127_5245322_0 AcrB/AcrD/AcrF family K18138,K18307 - - 0.0 1099.0
HKD3_k127_5245322_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 304.0
HKD3_k127_5275836_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006728 497.0
HKD3_k127_5275836_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003307 250.0
HKD3_k127_5275836_2 PFAM secretion protein HlyD family protein K03543,K15549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004182 252.0
HKD3_k127_5275836_3 Malic enzyme K00027 - 1.1.1.38 0.0000000000000009663 79.0
HKD3_k127_5275836_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000009717 64.0
HKD3_k127_5275836_5 Dienelactone hydrolase - - - 0.0000003612 55.0
HKD3_k127_5275836_6 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00001123 50.0
HKD3_k127_5300896_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 512.0
HKD3_k127_5300896_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 505.0
HKD3_k127_5371341_0 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 547.0
HKD3_k127_5371341_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000006523 177.0
HKD3_k127_5371341_2 Multidrug resistance protein K11741 - - 0.00000000000006798 72.0
HKD3_k127_5371341_3 MaoC like domain K14449 GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.000007225 49.0
HKD3_k127_5400228_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 3.294e-292 919.0
HKD3_k127_5400228_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 460.0
HKD3_k127_5408624_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 415.0
HKD3_k127_5408624_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 380.0
HKD3_k127_5408624_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000649 251.0
HKD3_k127_5408624_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000006197 171.0
HKD3_k127_5408624_4 Pyrimidine 5'-nucleotidase K07025 - - 0.00000000000000000000000000000000000836 139.0
HKD3_k127_5427763_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 409.0
HKD3_k127_5427763_1 Peptidase S24-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 288.0
HKD3_k127_5427763_2 protein conserved in bacteria - - - 0.00000000000000000000000000000001147 130.0
HKD3_k127_5427763_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000008072 124.0
HKD3_k127_5427763_4 Lysozyme inhibitor LprI - - - 0.0000000000000000000001687 109.0
HKD3_k127_5427763_5 Lysozyme inhibitor LprI - - - 0.000000000000000003344 96.0
HKD3_k127_5427763_6 nuclease - - - 0.000000000000000003512 94.0
HKD3_k127_543328_0 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 455.0
HKD3_k127_543328_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 437.0
HKD3_k127_543328_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000003321 198.0
HKD3_k127_5502743_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 371.0
HKD3_k127_5502743_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 319.0
HKD3_k127_5502743_2 oxidase, subunit K00425 - 1.10.3.14 0.00000000000000000000000000003093 119.0
HKD3_k127_555910_0 MMPL family K07003 - - 1.474e-270 854.0
HKD3_k127_555910_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.05e-198 628.0
HKD3_k127_555910_2 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000007185 231.0
HKD3_k127_555910_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000002314 212.0
HKD3_k127_555910_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000002788 206.0
HKD3_k127_555910_5 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000001271 149.0
HKD3_k127_5570836_0 DNA polymerase K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1312.0
HKD3_k127_5570836_1 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 396.0
HKD3_k127_5570836_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
HKD3_k127_5570836_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 308.0
HKD3_k127_5634586_0 Cell wall-binding repeat protein - - - 0.00000003955 60.0
HKD3_k127_5634586_1 - - - - 0.00001489 55.0
HKD3_k127_5732880_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.514e-295 915.0
HKD3_k127_5732880_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
HKD3_k127_5732880_2 PRC-barrel domain - - - 0.0000000000000000006493 96.0
HKD3_k127_5732880_3 MAPEG family - - - 0.0000000000003281 78.0
HKD3_k127_5732880_4 DoxX-like family - - - 0.0000001104 57.0
HKD3_k127_5745464_0 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 454.0
HKD3_k127_5745464_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 372.0
HKD3_k127_5745464_2 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000000000000000000000003151 194.0
HKD3_k127_5745464_3 Belongs to the HesB IscA family K13628,K15724 - - 0.00000000000000000000000000000000000000401 153.0
HKD3_k127_5745464_4 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000721 82.0
HKD3_k127_5758933_0 Two component transcriptional regulator PhoB, winged helix family K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 362.0
HKD3_k127_5758933_1 GcrA cell cycle regulator K13583 - - 0.0000000000000000000000000000000000000000000000000000000004243 207.0
HKD3_k127_5758933_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000002819 123.0
HKD3_k127_5758933_3 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00004872 46.0
HKD3_k127_5765221_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 585.0
HKD3_k127_5765221_1 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001152 209.0
HKD3_k127_5765221_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000002942 132.0
HKD3_k127_5769522_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 522.0
HKD3_k127_5769522_1 PFAM Methylene-tetrahydromethanopterin dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 404.0
HKD3_k127_5769522_2 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002726 264.0
HKD3_k127_5769522_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018 - 1.1.1.29 0.000000000000000000000000000000000000000003131 155.0
HKD3_k127_5964635_0 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000006935 130.0
HKD3_k127_5964635_1 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.000000000000000000001682 94.0
HKD3_k127_5964635_3 AntiSigma factor - - - 0.0000000000000001628 91.0
HKD3_k127_5964635_4 Sigma-70, region 4 K03088 - - 0.000000006353 64.0
HKD3_k127_5989577_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 348.0
HKD3_k127_5989577_1 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001203 225.0
HKD3_k127_5989577_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.0000000000000000008594 89.0
HKD3_k127_5989577_3 PFAM Sporulation domain protein - - - 0.00000000000008479 76.0
HKD3_k127_6042984_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 389.0
HKD3_k127_6042984_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 351.0
HKD3_k127_6042984_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 317.0
HKD3_k127_6042984_3 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 290.0
HKD3_k127_6042984_4 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008746 280.0
HKD3_k127_6042984_5 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000002607 234.0
HKD3_k127_6042984_6 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000781 134.0
HKD3_k127_6046494_0 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 459.0
HKD3_k127_6046494_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006282 271.0
HKD3_k127_6046494_2 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000155 246.0
HKD3_k127_6046494_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000002674 220.0
HKD3_k127_6046494_5 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000002405 91.0
HKD3_k127_6060683_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1020.0
HKD3_k127_6060683_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 2.977e-233 731.0
HKD3_k127_6060683_2 PFAM peptidase M13 K01415 - 3.4.24.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 483.0
HKD3_k127_6060683_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 415.0
HKD3_k127_6060683_4 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000156 162.0
HKD3_k127_6060683_5 - - - - 0.00000000000000000000000000000001949 128.0
HKD3_k127_6060683_6 Glutamine amido-transferase K01951 - 6.3.5.2 0.00005417 53.0
HKD3_k127_6122541_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.636e-301 930.0
HKD3_k127_6122541_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.351e-213 676.0
HKD3_k127_6122541_10 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000006611 179.0
HKD3_k127_6122541_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000005061 149.0
HKD3_k127_6122541_12 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000006933 148.0
HKD3_k127_6122541_13 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000005945 99.0
HKD3_k127_6122541_2 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 470.0
HKD3_k127_6122541_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 432.0
HKD3_k127_6122541_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 316.0
HKD3_k127_6122541_5 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000006691 257.0
HKD3_k127_6122541_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HKD3_k127_6122541_7 Domain of unknown function (DUF1835) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002328 249.0
HKD3_k127_6122541_8 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000003982 203.0
HKD3_k127_6122541_9 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.00000000000000000000000000000000000000000000000000000000789 203.0
HKD3_k127_6125763_0 acyl-CoA dehydrogenase K14448 - 1.3.8.12 2.373e-241 757.0
HKD3_k127_6125763_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 325.0
HKD3_k127_6125763_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000036 276.0
HKD3_k127_6125763_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 262.0
HKD3_k127_6125763_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000006518 139.0
HKD3_k127_6125763_5 PFAM Hypoxia induced protein conserved region - - - 0.0000000000000001886 82.0
HKD3_k127_6135303_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 616.0
HKD3_k127_6135303_1 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 344.0
HKD3_k127_6137555_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 532.0
HKD3_k127_6137555_1 endonuclease III K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 438.0
HKD3_k127_6137555_2 DSBA oxidoreductase - - - 0.0000000000000000000000000000001536 132.0
HKD3_k127_6137555_3 Protein of unknown function (DUF721) - - - 0.00000000000000000000000002765 116.0
HKD3_k127_6160362_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 481.0
HKD3_k127_6160362_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000004061 125.0
HKD3_k127_6164492_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 376.0
HKD3_k127_6164492_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 317.0
HKD3_k127_6164492_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000009615 153.0
HKD3_k127_6183203_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1049.0
HKD3_k127_6183203_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 510.0
HKD3_k127_6183203_2 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 334.0
HKD3_k127_6183203_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 299.0
HKD3_k127_6183203_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
HKD3_k127_6183203_5 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001353 242.0
HKD3_k127_6183203_6 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000002233 213.0
HKD3_k127_6183203_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000001751 190.0
HKD3_k127_6183203_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000003018 165.0
HKD3_k127_6202810_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 399.0
HKD3_k127_6202810_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 394.0
HKD3_k127_6202810_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000001424 210.0
HKD3_k127_6202810_3 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000007096 100.0
HKD3_k127_6202810_4 Protein of unknown function DUF47 K07220 - - 0.0000000000000000001032 91.0
HKD3_k127_6207052_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 4.725e-227 711.0
HKD3_k127_6207052_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 363.0
HKD3_k127_6207052_10 Cobalt transporter subunit CbtB - - - 0.000000000001425 70.0
HKD3_k127_6207052_11 PFAM Aminotransferase class I and II K02225 - - 0.0000002447 61.0
HKD3_k127_6207052_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 341.0
HKD3_k127_6207052_3 cobalt transporter, subunit CbtA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
HKD3_k127_6207052_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000037 229.0
HKD3_k127_6207052_5 Extensin-like protein C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000001459 215.0
HKD3_k127_6207052_6 PFAM Aminotransferase class I and II K02225 - - 0.0000000000000000000000000000000000000000000000000000002895 199.0
HKD3_k127_6207052_7 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000001176 198.0
HKD3_k127_6207052_8 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000004957 195.0
HKD3_k127_6207052_9 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K02225 - - 0.0000000000000000000001675 99.0
HKD3_k127_620890_0 Protein of unknown function, DUF255 K06888 - - 2.855e-216 687.0
HKD3_k127_6223085_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.37e-280 870.0
HKD3_k127_6223085_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 293.0
HKD3_k127_6223085_2 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
HKD3_k127_6223085_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000001863 154.0
HKD3_k127_6240465_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 406.0
HKD3_k127_6240465_1 Molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
HKD3_k127_625138_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 544.0
HKD3_k127_625138_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 384.0
HKD3_k127_625138_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0005787 45.0
HKD3_k127_6282569_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 9.094e-219 684.0
HKD3_k127_6282569_1 Phosphopantetheine attachment site K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000004639 146.0
HKD3_k127_6287330_0 Diguanylate cyclase phosphodiesterase with PAS PAC K13245 - 3.1.4.52 1.306e-210 670.0
HKD3_k127_6287330_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 524.0
HKD3_k127_6287330_2 Cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 417.0
HKD3_k127_6287330_3 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 418.0
HKD3_k127_6287330_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000008246 264.0
HKD3_k127_6287330_5 SURF1 family K14998 GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HKD3_k127_6287330_6 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000006003 201.0
HKD3_k127_6287330_7 Protein of unknown function (DUF983) - - - 0.000000000000000000000000000000000000001112 153.0
HKD3_k127_6287330_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000009668 79.0
HKD3_k127_6287330_9 - - - - 0.00000008045 56.0
HKD3_k127_6309522_0 Amidohydrolase family K01465 - 3.5.2.3 4.989e-198 631.0
HKD3_k127_6309522_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 297.0
HKD3_k127_6309522_2 Belongs to the GcvT family K06980,K22073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001691 266.0
HKD3_k127_6309522_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002638 262.0
HKD3_k127_6309522_4 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000000007144 208.0
HKD3_k127_6309522_5 - - - - 0.0000000000000000000000000000000007599 138.0
HKD3_k127_6309522_6 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.0000000000000000003644 89.0
HKD3_k127_6309522_7 - - - - 0.00000000000000002863 85.0
HKD3_k127_6341_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 586.0
HKD3_k127_6341_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 443.0
HKD3_k127_6341_2 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 387.0
HKD3_k127_6341_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 342.0
HKD3_k127_6341_4 Protein of unknown function (DUF805) - - - 0.0000000000000000000003931 101.0
HKD3_k127_6341_5 TIR domain - - - 0.000000000000000006258 87.0
HKD3_k127_6341_6 Tetratricopeptide repeat - - - 0.000000000000000337 83.0
HKD3_k127_6341_7 Protein of unknown function (DUF805) - - - 0.0000000001028 68.0
HKD3_k127_6341_8 serine threonine protein kinase K12132 - 2.7.11.1 0.00000003897 62.0
HKD3_k127_6342293_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1262.0
HKD3_k127_6342293_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 473.0
HKD3_k127_6342293_2 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000003405 183.0
HKD3_k127_6342293_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000007269 180.0
HKD3_k127_6342293_4 phasin family - - - 0.0000000000000000000000000000000001247 135.0
HKD3_k127_6342293_5 Dodecin K09165 - - 0.000000000000000000006408 94.0
HKD3_k127_6363050_0 Protein of unknown function (DUF1513) K09947 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 328.0
HKD3_k127_6363050_1 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003149 278.0
HKD3_k127_6363050_2 Imelysin K07338 - - 0.0000000000000000000000000000000000000000000000000000002532 204.0
HKD3_k127_6382946_0 - - - - 0.000000003026 68.0
HKD3_k127_6412734_0 Beta-eliminating lyase K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 7.327e-220 688.0
HKD3_k127_6412734_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 358.0
HKD3_k127_6412734_2 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 322.0
HKD3_k127_6412734_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000007496 243.0
HKD3_k127_6412734_4 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
HKD3_k127_6412734_5 structural constituent of ribosome K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003722 135.0
HKD3_k127_6412734_6 PFAM polysaccharide deacetylase - - - 0.0000000000000002601 81.0
HKD3_k127_6412734_7 Polysaccharide deacetylase - - - 0.00000000000007886 72.0
HKD3_k127_6412734_8 Protein of unknown function (DUF2842) - - - 0.0000000000004013 72.0
HKD3_k127_6421798_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 4.396e-236 741.0
HKD3_k127_6421798_1 unusual protein kinase - - - 1.113e-213 672.0
HKD3_k127_6421798_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 495.0
HKD3_k127_6421798_3 Oligopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 476.0
HKD3_k127_6421798_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.00000000000000000000000000000000002519 146.0
HKD3_k127_6421798_5 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000004052 134.0
HKD3_k127_6421798_6 Protein of unknown function (DUF3574) - - - 0.0000000000000000008594 89.0
HKD3_k127_6421798_7 diguanylate cyclase - - - 0.0000000000000001933 85.0
HKD3_k127_6421798_8 Addiction module antidote - - - 0.00000004052 54.0
HKD3_k127_6427069_0 biosynthesis protein - GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 593.0
HKD3_k127_6427069_1 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 355.0
HKD3_k127_6427069_2 epimerase dehydratase K01784,K19997 - 5.1.3.2,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000009902 255.0
HKD3_k127_6427069_3 Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000004501 213.0
HKD3_k127_6427069_4 LUD domain K00782 - - 0.000000000000009309 74.0
HKD3_k127_6427069_5 Belongs to the 'phage' integrase family - - - 0.00000000000001198 75.0
HKD3_k127_6441749_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 456.0
HKD3_k127_6441749_1 - - - - 0.00000001294 62.0
HKD3_k127_6530780_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 1274.0
HKD3_k127_6530780_1 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000005888 134.0
HKD3_k127_6567467_0 sodium channel regulator activity K09639 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0015672,GO:0016020,GO:0016247,GO:0016787,GO:0017080,GO:0017171,GO:0019538,GO:0030001,GO:0031224,GO:0031225,GO:0031226,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046658,GO:0051179,GO:0051234,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0071944,GO:0098772,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000004161 155.0
HKD3_k127_6567467_1 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000004161 155.0
HKD3_k127_6567467_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000001988 126.0
HKD3_k127_6567467_4 COG5640 Secreted trypsin-like serine protease - - - 0.0000000000001242 78.0
HKD3_k127_6592727_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1012.0
HKD3_k127_6592727_1 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 627.0
HKD3_k127_6592727_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009974 273.0
HKD3_k127_6610596_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 533.0
HKD3_k127_6610596_1 Conserved protein of DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009036 232.0
HKD3_k127_6610596_2 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000006684 90.0
HKD3_k127_6629771_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 437.0
HKD3_k127_6629771_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 368.0
HKD3_k127_6629771_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 332.0
HKD3_k127_6629771_3 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000006568 175.0
HKD3_k127_6629771_4 Protein of unknown function (DUF2628) - - - 0.00000000000000000604 91.0
HKD3_k127_6629771_5 - - - - 0.00000000001654 68.0
HKD3_k127_6639097_0 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 426.0
HKD3_k127_6639097_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 330.0
HKD3_k127_6639097_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.0000000000000000000007461 102.0
HKD3_k127_6639097_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000002083 79.0
HKD3_k127_6647401_0 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 490.0
HKD3_k127_6647401_1 LppC putative lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 408.0
HKD3_k127_6647401_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 317.0
HKD3_k127_6647401_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
HKD3_k127_6647401_4 Uncharacterised protein family UPF0102 K07460 - - 0.00000001333 61.0
HKD3_k127_6647401_5 2TM domain - - - 0.0000029 55.0
HKD3_k127_6647401_6 2TM domain - - - 0.000003941 55.0
HKD3_k127_6671862_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 3.915e-263 817.0
HKD3_k127_6671862_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 3.484e-258 817.0
HKD3_k127_6671862_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000005471 52.0
HKD3_k127_6671862_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000009408 263.0
HKD3_k127_6671862_3 PFAM O-methyltransferase family 2 K09846 - 2.1.1.210 0.00000000000000000000000000000000000000000000000000000000000000004378 236.0
HKD3_k127_6671862_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000001407 160.0
HKD3_k127_6671862_5 D-ala D-ala ligase C-terminus - - - 0.0000000000000000000000000005588 116.0
HKD3_k127_6671862_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000001748 81.0
HKD3_k127_6671862_7 Protein of unknown function (DUF4239) - - - 0.0000000000001692 72.0
HKD3_k127_6671862_8 Alpha beta hydrolase - - - 0.00000000000183 75.0
HKD3_k127_6671862_9 protein conserved in bacteria - - - 0.0000000197 57.0
HKD3_k127_6676678_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 461.0
HKD3_k127_6676678_1 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 382.0
HKD3_k127_6676678_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000136 50.0
HKD3_k127_6679048_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 523.0
HKD3_k127_6679048_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 407.0
HKD3_k127_6696418_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 464.0
HKD3_k127_6696418_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 303.0
HKD3_k127_6696418_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000003819 246.0
HKD3_k127_6696418_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000002576 201.0
HKD3_k127_6696418_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000009089 187.0
HKD3_k127_6696418_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000008636 170.0
HKD3_k127_6696418_6 OmpW family K07275 - - 0.000000000000000000000000000000009083 132.0
HKD3_k127_6696418_7 Crp-like helix-turn-helix domain K01420 - - 0.0000000008738 68.0
HKD3_k127_6696418_8 Crp-like helix-turn-helix domain K01420 - - 0.00000000965 68.0
HKD3_k127_6696418_9 OmpW family K07275 - - 0.0002223 43.0
HKD3_k127_6702669_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.671e-279 887.0
HKD3_k127_6702669_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 461.0
HKD3_k127_6702669_2 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 374.0
HKD3_k127_6702669_3 ABC-type transport auxiliary lipoprotein component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 346.0
HKD3_k127_6702669_4 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001388 231.0
HKD3_k127_6702669_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001224 214.0
HKD3_k127_6702669_6 - - - - 0.0000000000000000000000000000000000002343 146.0
HKD3_k127_675652_0 E1 component K00164 - 1.2.4.2 1.174e-250 780.0
HKD3_k127_675652_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000001104 147.0
HKD3_k127_675727_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 444.0
HKD3_k127_675727_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 387.0
HKD3_k127_675727_2 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000004981 237.0
HKD3_k127_675727_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000008613 228.0
HKD3_k127_6757453_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1153.0
HKD3_k127_6757453_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.648e-267 845.0
HKD3_k127_6757453_2 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000000000000000004171 188.0
HKD3_k127_6757453_3 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000009713 101.0
HKD3_k127_6833520_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1388.0
HKD3_k127_6833520_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 496.0
HKD3_k127_6833520_10 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000001621 169.0
HKD3_k127_6833520_11 PFAM regulatory protein LysR K02019 - - 0.0000000000000000000000000000000000000007621 152.0
HKD3_k127_6833520_12 Bacterial SH3 domain - - - 0.000000000002576 74.0
HKD3_k127_6833520_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 484.0
HKD3_k127_6833520_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 396.0
HKD3_k127_6833520_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 371.0
HKD3_k127_6833520_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799,K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 369.0
HKD3_k127_6833520_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 340.0
HKD3_k127_6833520_7 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000006539 240.0
HKD3_k127_6833520_8 MEKHLA domain protein - - - 0.0000000000000000000000000000000000000000000000000000003834 200.0
HKD3_k127_6833520_9 TOBE domain K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000005281 198.0
HKD3_k127_6876735_0 PFAM binding-protein-dependent transport systems inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 563.0
HKD3_k127_6876735_1 N-terminal TM domain of oligopeptide transport permease C K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000006646 133.0
HKD3_k127_6896273_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 521.0
HKD3_k127_6896273_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 501.0
HKD3_k127_6896273_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004074 253.0
HKD3_k127_6896273_3 Domain of unknown function (DUF4010) - - - 0.000000000004794 68.0
HKD3_k127_6927968_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1022.0
HKD3_k127_6927968_1 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 557.0
HKD3_k127_6927968_10 PRC-barrel domain - - - 0.00000000000000000000000000003258 124.0
HKD3_k127_6927968_11 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000368 111.0
HKD3_k127_6927968_12 Protein of unknown function (DUF3309) - - - 0.000000000000002742 78.0
HKD3_k127_6927968_13 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0001155 49.0
HKD3_k127_6927968_2 amine oxidase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 494.0
HKD3_k127_6927968_3 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 456.0
HKD3_k127_6927968_4 Hopene-associated glycosyltransferase HpnB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 452.0
HKD3_k127_6927968_5 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 421.0
HKD3_k127_6927968_6 Squalene synthase HpnD K02291,K21678 - 2.5.1.103,2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 327.0
HKD3_k127_6927968_7 squalene synthase HpnC K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 329.0
HKD3_k127_6927968_8 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000000000000000000000000000002219 163.0
HKD3_k127_6927968_9 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000003215 150.0
HKD3_k127_6943464_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 502.0
HKD3_k127_6943464_1 pyridine nucleotide-disulfide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004294 255.0
HKD3_k127_6943464_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000001415 143.0
HKD3_k127_6943464_3 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000002731 104.0
HKD3_k127_7002324_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1149.0
HKD3_k127_7002324_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1039.0
HKD3_k127_7002324_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 529.0
HKD3_k127_7002324_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 486.0
HKD3_k127_7002324_4 Belongs to the HpcH HpaI aldolase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 424.0
HKD3_k127_7002324_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 353.0
HKD3_k127_7002324_6 3' exoribonuclease family, domain 2 K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
HKD3_k127_7002324_7 - - - - 0.0000000000000000005007 91.0
HKD3_k127_7122232_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 503.0
HKD3_k127_7122232_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000001704 125.0
HKD3_k127_7184999_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 2.939e-245 769.0
HKD3_k127_7184999_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 514.0
HKD3_k127_7184999_2 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 378.0
HKD3_k127_7184999_3 N-terminal TM domain of oligopeptide transport permease C K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 318.0
HKD3_k127_7184999_4 NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
HKD3_k127_721678_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 482.0
HKD3_k127_721678_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 491.0
HKD3_k127_721678_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000001448 145.0
HKD3_k127_721678_3 MAPEG family - - - 0.0000000000000000000000000000000006199 135.0
HKD3_k127_721678_4 - - - - 0.000000000000003806 86.0
HKD3_k127_7251585_0 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0044237,GO:0044281 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 385.0
HKD3_k127_7251585_1 Cyclohydrolase (MCH) K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 374.0
HKD3_k127_7251585_2 chorismate binding enzyme K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 355.0
HKD3_k127_7251585_3 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 335.0
HKD3_k127_7251585_4 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009869 276.0
HKD3_k127_7251585_5 TIGRFAM beta-ribofuranosylaminobenzene 5'-phosphate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001493 265.0
HKD3_k127_7251585_6 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000000000000000000001848 220.0
HKD3_k127_7251585_7 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000009834 218.0
HKD3_k127_7251585_8 GXGXG motif K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000008627 222.0
HKD3_k127_7252125_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 560.0
HKD3_k127_7252125_1 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 537.0
HKD3_k127_7252125_10 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000304 141.0
HKD3_k127_7252125_11 FecR protein - - - 0.000000000000000000002688 100.0
HKD3_k127_7252125_12 KR domain - - - 0.0000000009185 69.0
HKD3_k127_7252125_13 - - - - 0.00000008567 58.0
HKD3_k127_7252125_14 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000007656 60.0
HKD3_k127_7252125_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 377.0
HKD3_k127_7252125_3 Cold-shock K03704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 291.0
HKD3_k127_7252125_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006707 265.0
HKD3_k127_7252125_5 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000001149 229.0
HKD3_k127_7252125_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000001022 186.0
HKD3_k127_7252125_7 Chromate K07240 - - 0.000000000000000000000000000000000000000003914 158.0
HKD3_k127_7252125_8 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000002402 145.0
HKD3_k127_7252125_9 PFAM ETC complex I subunit conserved region K00329 - 1.6.5.3 0.00000000000000000000000000000000009536 136.0
HKD3_k127_7266172_0 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 332.0
HKD3_k127_7266172_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000001638 155.0
HKD3_k127_7266172_2 cytochrome - - - 0.0003641 43.0
HKD3_k127_7269332_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 516.0
HKD3_k127_7269332_1 ATPase involved in DNA repair K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 478.0
HKD3_k127_7269332_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000000000002766 180.0
HKD3_k127_7269332_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000005134 159.0
HKD3_k127_7269332_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000007278 136.0
HKD3_k127_7269332_5 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000001445 128.0
HKD3_k127_7269332_6 Histidine Phosphotransfer domain - - - 0.00000000000000000000008478 102.0
HKD3_k127_7269332_7 Methyltransferase domain - - - 0.000000005044 61.0
HKD3_k127_7276438_0 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1034.0
HKD3_k127_7276438_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000003579 166.0
HKD3_k127_7276438_2 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000021 157.0
HKD3_k127_7276438_3 Ribosomal L28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002156 132.0
HKD3_k127_730155_0 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 422.0
HKD3_k127_730155_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001724 252.0
HKD3_k127_730155_2 ABC transporter K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000003851 217.0
HKD3_k127_730155_3 protein tyrosine phosphatase - - - 0.0000000000000000000000000000000000000000000000000006636 189.0
HKD3_k127_730155_4 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000007497 58.0
HKD3_k127_7314781_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 1.19e-219 689.0
HKD3_k127_7314781_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 582.0
HKD3_k127_7314781_10 Squalene/phytoene synthase K02291,K18163 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000291 198.0
HKD3_k127_7314781_11 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000002885 160.0
HKD3_k127_7314781_12 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000008746 127.0
HKD3_k127_7314781_13 Preprotein translocase subunit (YajC) K03210 - - 0.0000000000000000000000000004778 117.0
HKD3_k127_7314781_14 DNA mediated transformation K04096 - - 0.000000000000000000005482 100.0
HKD3_k127_7314781_15 Protein of unknown function (DUF3175) - - - 0.000000000000000001232 89.0
HKD3_k127_7314781_16 Putative molybdenum carrier - - - 0.0000000005207 62.0
HKD3_k127_7314781_17 - - - - 0.0000000005644 66.0
HKD3_k127_7314781_18 Cupin domain - - - 0.000002436 52.0
HKD3_k127_7314781_2 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 396.0
HKD3_k127_7314781_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 338.0
HKD3_k127_7314781_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 334.0
HKD3_k127_7314781_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 320.0
HKD3_k127_7314781_6 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 295.0
HKD3_k127_7314781_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 265.0
HKD3_k127_7314781_8 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001077 258.0
HKD3_k127_7314781_9 Protein of unknown function (DUF1097) - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
HKD3_k127_7322688_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.783e-242 762.0
HKD3_k127_7322688_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 1.372e-239 749.0
HKD3_k127_7322688_10 - - - - 0.000000000000000000000000000000000000000000000000000002112 206.0
HKD3_k127_7322688_11 rRNA binding K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000242 196.0
HKD3_k127_7322688_12 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000905 164.0
HKD3_k127_7322688_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000008938 139.0
HKD3_k127_7322688_14 Glutaredoxin - - - 0.0002383 48.0
HKD3_k127_7322688_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 6.974e-211 665.0
HKD3_k127_7322688_3 KaiC K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 565.0
HKD3_k127_7322688_4 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 371.0
HKD3_k127_7322688_5 Hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 359.0
HKD3_k127_7322688_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 365.0
HKD3_k127_7322688_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
HKD3_k127_7322688_8 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000002919 241.0
HKD3_k127_7322688_9 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001113 227.0
HKD3_k127_7351592_0 cobalt chelatase K09883 - 6.6.1.2 2.07e-240 763.0
HKD3_k127_7351592_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 582.0
HKD3_k127_7351592_2 Domain of unknown function DUF21 K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 430.0
HKD3_k127_7351592_3 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 282.0
HKD3_k127_7351592_4 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000001252 213.0
HKD3_k127_7351592_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000007989 133.0
HKD3_k127_7351592_6 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000000002974 113.0
HKD3_k127_7371930_0 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 448.0
HKD3_k127_7371930_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 425.0
HKD3_k127_7371930_2 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 306.0
HKD3_k127_7371930_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001884 283.0
HKD3_k127_7371930_4 - - - - 0.000000000000000000000000000000000001276 144.0
HKD3_k127_7371930_5 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000333 146.0
HKD3_k127_7371930_6 AsmA-like C-terminal region K07289 - - 0.0000000000001019 85.0
HKD3_k127_7371930_7 Phasin protein - - - 0.00000002771 59.0
HKD3_k127_738649_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 3.321e-237 741.0
HKD3_k127_738649_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 524.0
HKD3_k127_738649_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
HKD3_k127_741109_0 Belongs to the CarB family K01955 - 6.3.5.5 1.547e-260 809.0
HKD3_k127_741109_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 536.0
HKD3_k127_741109_2 Yqey-like protein K09117 - - 0.000000000000002593 79.0
HKD3_k127_7426366_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 452.0
HKD3_k127_7426366_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000387 226.0
HKD3_k127_7426366_2 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000003555 222.0
HKD3_k127_7426366_3 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000000000000000000000000000000001654 174.0
HKD3_k127_7426366_4 Sugar efflux transporter for intercellular exchange K15383 - - 0.000003036 50.0
HKD3_k127_7448860_0 ABC transporter K15738 - - 5.119e-282 875.0
HKD3_k127_7448860_1 reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 449.0
HKD3_k127_7448860_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 368.0
HKD3_k127_7448860_3 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001802 268.0
HKD3_k127_7448860_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001162 153.0
HKD3_k127_7448860_5 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000006147 106.0
HKD3_k127_7448860_6 Protein of unknown function (DUF533) - - - 0.0004277 49.0
HKD3_k127_7493213_0 ATP-grasp domain K09181 - - 2.376e-303 954.0
HKD3_k127_7497322_0 MiaB-like tRNA modifying K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 565.0
HKD3_k127_7497322_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 463.0
HKD3_k127_7497322_2 SRP54-type protein, GTPase domain K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 398.0
HKD3_k127_7497322_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 368.0
HKD3_k127_7531675_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 462.0
HKD3_k127_7531675_1 Putative peptidoglycan binding domain K21470,K21572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 368.0
HKD3_k127_7531675_2 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002755 279.0
HKD3_k127_7531675_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
HKD3_k127_7531675_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HKD3_k127_7531675_5 Extensin family - - - 0.0000000000000000000000000000000000000000002777 173.0
HKD3_k127_7531675_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000001715 145.0
HKD3_k127_7531675_7 membrane protein domain - - - 0.0000000000000000000000000000000000008248 145.0
HKD3_k127_7574097_0 Pyruvate kinase, alpha/beta domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 612.0
HKD3_k127_7574097_1 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 322.0
HKD3_k127_7574097_10 Protein of unknown function (DUF1244) K09948 - - 0.0000000000000000000000000000008022 136.0
HKD3_k127_7574097_11 Tetratricopeptide repeat - - - 0.000000000000000000000000007029 123.0
HKD3_k127_7574097_12 Belongs to the UPF0335 family - - - 0.0000000000000000000000006944 106.0
HKD3_k127_7574097_13 Ribosomal protein L36 K02919 - - 0.00000000001714 68.0
HKD3_k127_7574097_14 - - - - 0.000001025 56.0
HKD3_k127_7574097_15 - - - - 0.0004131 46.0
HKD3_k127_7574097_2 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 315.0
HKD3_k127_7574097_3 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002885 276.0
HKD3_k127_7574097_4 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000000000000005819 207.0
HKD3_k127_7574097_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000129 190.0
HKD3_k127_7574097_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000002847 174.0
HKD3_k127_7574097_7 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000001396 168.0
HKD3_k127_7574097_8 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000001733 164.0
HKD3_k127_7574097_9 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000003711 143.0
HKD3_k127_7596086_0 PFAM DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000002338 196.0
HKD3_k127_7596086_1 Adenylate - - - 0.000000000000007321 88.0
HKD3_k127_7604929_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 4.742e-311 970.0
HKD3_k127_7604929_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 405.0
HKD3_k127_7604929_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 376.0
HKD3_k127_7604929_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 359.0
HKD3_k127_7604929_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
HKD3_k127_7604929_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008854 257.0
HKD3_k127_7604929_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000004433 203.0
HKD3_k127_7604929_7 Protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000006868 173.0
HKD3_k127_7604929_8 Cysteine-rich secretory protein family - - - 0.0000000000000000000000003861 112.0
HKD3_k127_7614163_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 525.0
HKD3_k127_7614163_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 374.0
HKD3_k127_7614163_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000723 257.0
HKD3_k127_7614163_3 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000001777 235.0
HKD3_k127_7614163_4 CHAD - - - 0.00000000000000000000000000000000000000001599 167.0
HKD3_k127_7614163_5 thiamine biosynthesis K03154 - - 0.00000000004782 69.0
HKD3_k127_7627583_0 Stimulus-sensing domain K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 1.014e-207 662.0
HKD3_k127_7627583_1 Transcriptional regulatory protein, C terminal K14981 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 398.0
HKD3_k127_7627583_2 PFAM peptidase M13 K01415 - 3.4.24.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005075 288.0
HKD3_k127_7627583_3 pyridoxamine 5'-phosphate K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
HKD3_k127_7627583_4 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000003556 197.0
HKD3_k127_7627583_5 HPr Serine kinase C-terminal domain K06023 - - 0.000000000000000000000000000003275 124.0
HKD3_k127_7627583_6 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.0000000000000000000000013 107.0
HKD3_k127_7627583_7 Aspartyl protease - - - 0.0000000000000000000003538 107.0
HKD3_k127_7627583_8 Phasin protein - - - 0.0000009868 53.0
HKD3_k127_7647911_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 325.0
HKD3_k127_7647911_1 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000007058 170.0
HKD3_k127_7647911_2 Protein of unknown function (DUF1489) - - - 0.00000000000000000000000000000000000000005641 156.0
HKD3_k127_7647911_3 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000002675 147.0
HKD3_k127_7647911_4 Putative DNA-binding domain - - - 0.000000000000000006066 86.0
HKD3_k127_7675915_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 383.0
HKD3_k127_7675915_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
HKD3_k127_7675915_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 0.0000000009091 61.0
HKD3_k127_7677021_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1633.0
HKD3_k127_7677021_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 290.0
HKD3_k127_7677021_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000002122 224.0
HKD3_k127_7677021_3 NADH ubiquinone oxidoreductase 17.2 kD subunit K00356 - 1.6.99.3 0.000000000000000000000000000000000000000000001113 168.0
HKD3_k127_7677021_4 Response regulator receiver K03413 - - 0.00003596 52.0
HKD3_k127_7775888_0 Sulfite reductase K00381 - 1.8.1.2 5.577e-226 722.0
HKD3_k127_7775888_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 528.0
HKD3_k127_7775888_2 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 495.0
HKD3_k127_7775888_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 377.0
HKD3_k127_7775888_4 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 326.0
HKD3_k127_7775888_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002809 263.0
HKD3_k127_7775888_6 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000000000000003428 161.0
HKD3_k127_7775888_7 Protein of unknown function (DUF2849) - - - 0.000000000005642 70.0
HKD3_k127_7775888_8 Parallel beta-helix repeats - - - 0.00005664 47.0
HKD3_k127_7779151_0 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 394.0
HKD3_k127_7779151_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 335.0
HKD3_k127_7779151_2 (ABC) transporter, permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 328.0
HKD3_k127_7779151_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 - - 0.000000000000000000000000000000000000000000000007447 174.0
HKD3_k127_7779151_4 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000001739 98.0
HKD3_k127_7803668_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 9.648e-196 616.0
HKD3_k127_7803668_1 Acetoacetyl-CoA reductase K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 336.0
HKD3_k127_7803668_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000008017 201.0
HKD3_k127_7803668_3 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000001871 194.0
HKD3_k127_7807600_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1215.0
HKD3_k127_7807600_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 371.0
HKD3_k127_7807600_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 352.0
HKD3_k127_7807600_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
HKD3_k127_7807600_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 269.0
HKD3_k127_7807600_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000003621 179.0
HKD3_k127_7807600_6 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000000000000000000000004978 157.0
HKD3_k127_7807600_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000008711 59.0
HKD3_k127_7826704_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 558.0
HKD3_k127_7826704_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 506.0
HKD3_k127_7826704_2 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 353.0
HKD3_k127_7826704_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 312.0
HKD3_k127_7826704_4 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000001503 83.0
HKD3_k127_7826704_5 Protein conserved in bacteria K09937 - - 0.0000000000000003546 79.0
HKD3_k127_7858213_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
HKD3_k127_7858213_1 Bacterial dnaA protein - - - 0.00000000000000000000000000000000007114 138.0
HKD3_k127_7880195_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1095.0
HKD3_k127_7880195_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 368.0
HKD3_k127_7880195_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 324.0
HKD3_k127_7880195_3 Cell Wall Hydrolase - - - 0.0000000000000000000000000000000000000000000000001441 191.0
HKD3_k127_8027599_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 391.0
HKD3_k127_8027599_1 Bacterial extracellular solute-binding proteins, family 5 Middle K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 372.0
HKD3_k127_8027599_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 337.0
HKD3_k127_8027599_3 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005042 265.0
HKD3_k127_8027599_4 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.0001561 44.0
HKD3_k127_8092873_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 502.0
HKD3_k127_8092873_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 297.0
HKD3_k127_8092873_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 285.0
HKD3_k127_8092873_3 GMC oxidoreductase K06151,K08261,K19813 - 1.1.5.9,1.1.99.21,1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006061 255.0
HKD3_k127_8092873_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000005088 134.0
HKD3_k127_8092873_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000008052 116.0
HKD3_k127_8092873_6 Membrane bound FAD containing D-sorbitol dehydrogenase - - - 0.00000000001807 69.0
HKD3_k127_8094923_0 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 588.0
HKD3_k127_8094923_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
HKD3_k127_8094923_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 297.0
HKD3_k127_8094923_3 Invasion associated locus B - - - 0.00000000000000000000000000000000000000000000000001382 184.0
HKD3_k127_8094923_4 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000007523 166.0
HKD3_k127_8110928_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 602.0
HKD3_k127_8110928_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000002392 195.0
HKD3_k127_8293305_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000003426 181.0
HKD3_k127_8293305_1 Glutaminase - - - 0.0000000000000000000000000000000000000001122 160.0
HKD3_k127_8304559_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 8.211e-204 638.0
HKD3_k127_8304559_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 563.0
HKD3_k127_8304559_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 373.0
HKD3_k127_8304559_3 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006004 277.0
HKD3_k127_8304559_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002312 240.0
HKD3_k127_8304559_5 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000006792 171.0
HKD3_k127_8304559_6 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000003211 126.0
HKD3_k127_8304559_7 Protein of unknown function, DUF488 - - - 0.000000007226 61.0
HKD3_k127_8304559_8 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000001183 63.0
HKD3_k127_8360719_0 synthase K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 469.0
HKD3_k127_8360719_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000065 207.0
HKD3_k127_8360719_2 Protein of unknown function (DUF1353) - - - 0.0000000000000000000000000004815 123.0
HKD3_k127_8360719_3 Oxidoreductase, short chain dehydrogenase reductase family protein - - - 0.000001265 51.0
HKD3_k127_8360719_4 B-1 B cell differentiation - - - 0.0005446 45.0
HKD3_k127_8409929_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1249.0
HKD3_k127_8409929_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000649 201.0
HKD3_k127_8464704_0 Oligoendopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 570.0
HKD3_k127_8464704_1 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000006263 227.0
HKD3_k127_84982_0 Erythromycin esterase K00573 - 2.1.1.77 4.469e-243 769.0
HKD3_k127_84982_1 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 439.0
HKD3_k127_84982_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 364.0
HKD3_k127_84982_3 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 296.0
HKD3_k127_84982_4 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000007331 188.0
HKD3_k127_84982_5 Putative metallopeptidase - - - 0.0000000000000000000000000000000000000001055 163.0
HKD3_k127_84982_6 - - - - 0.00000000000000000000000000000006919 128.0
HKD3_k127_84982_7 Putative metallopeptidase - - - 0.00000000000000000000000000002668 128.0
HKD3_k127_8571595_0 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 332.0
HKD3_k127_8571595_1 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 336.0
HKD3_k127_8571595_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 325.0
HKD3_k127_8571595_3 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000003199 189.0
HKD3_k127_8573427_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 1e-323 1007.0
HKD3_k127_8595017_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 349.0
HKD3_k127_8595017_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
HKD3_k127_8595017_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000006566 92.0
HKD3_k127_8715437_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 2.226e-269 858.0
HKD3_k127_8715437_1 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 439.0
HKD3_k127_8779759_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003362 256.0
HKD3_k127_8779759_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000001264 124.0
HKD3_k127_8779759_3 membrane - - - 0.00000000000000000000002864 113.0
HKD3_k127_8825073_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 501.0
HKD3_k127_8825073_1 Citrate synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 406.0
HKD3_k127_8827751_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 422.0
HKD3_k127_8827751_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009787 255.0
HKD3_k127_8900251_0 Protein of unknown function - - - 2.706e-207 682.0
HKD3_k127_8900251_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 596.0
HKD3_k127_8900251_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 359.0
HKD3_k127_8900251_3 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001547 263.0
HKD3_k127_8909055_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 525.0
HKD3_k127_8909055_1 Sigma-70, region 4 K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 466.0
HKD3_k127_8909055_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 388.0
HKD3_k127_8909055_4 Phage terminase large subunit K06909 - - 0.000006361 48.0
HKD3_k127_8929959_0 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 318.0
HKD3_k127_8929959_1 Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004334 259.0
HKD3_k127_8929959_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000006897 173.0
HKD3_k127_8929959_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000006728 157.0
HKD3_k127_8945860_0 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 1.011e-268 835.0
HKD3_k127_8945860_1 lipid A ABC exporter family, fused ATPase and inner membrane subunits K06147 - - 2.628e-219 696.0
HKD3_k127_8945860_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 425.0
HKD3_k127_8945860_3 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 398.0
HKD3_k127_8945860_4 Protein of unknown function (DUF1013) K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 314.0
HKD3_k127_8945860_5 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000003448 177.0
HKD3_k127_8945860_6 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000000000000000000000001205 160.0
HKD3_k127_8945860_7 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000002269 130.0
HKD3_k127_8945860_8 Protein of unknown function (DUF1192) - - - 0.000000002302 60.0
HKD3_k127_894695_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 546.0
HKD3_k127_894695_1 PFAM regulatory protein LuxR - - - 0.00000000001203 65.0
HKD3_k127_8996286_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 507.0
HKD3_k127_8996286_1 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000003442 236.0
HKD3_k127_8996286_2 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000001397 173.0
HKD3_k127_8996286_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000184 78.0
HKD3_k127_9080122_0 Heat shock 70 kDa protein K04043 - - 5.226e-320 986.0
HKD3_k127_9080122_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 554.0
HKD3_k127_9080122_2 AI-2E family transporter - - - 0.0000000000000000000000002325 117.0
HKD3_k127_9112537_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 569.0
HKD3_k127_9112537_1 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 344.0
HKD3_k127_9112537_2 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000006317 227.0
HKD3_k127_9112537_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000002441 219.0
HKD3_k127_9112537_4 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000006522 207.0
HKD3_k127_9112537_5 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000003068 153.0
HKD3_k127_9112537_6 Mitochondrial fission ELM1 K07276 - - 0.00000000000000001002 84.0
HKD3_k127_9112537_7 Belongs to the MEMO1 family K06990 - - 0.0000000000000003183 90.0
HKD3_k127_9112537_8 Belongs to the MEMO1 family K06990 - - 0.000000000004961 69.0
HKD3_k127_912334_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 529.0
HKD3_k127_912334_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 381.0
HKD3_k127_912334_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000001664 107.0
HKD3_k127_9155056_0 Domain of unknown function (DUF4159) - - - 1.575e-292 925.0
HKD3_k127_9155056_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000001893 203.0
HKD3_k127_9243073_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 557.0
HKD3_k127_9243073_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 388.0
HKD3_k127_9243073_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 391.0
HKD3_k127_9243073_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000005301 225.0
HKD3_k127_9259270_0 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 456.0
HKD3_k127_9259270_1 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 413.0
HKD3_k127_9259270_2 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000001098 207.0
HKD3_k127_9259270_3 Belongs to the globin family - - - 0.000000000001773 76.0
HKD3_k127_9260828_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 436.0
HKD3_k127_9260828_1 FAD binding domain - - - 0.00000000000000000000000000000000001169 148.0
HKD3_k127_9376711_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 9.989e-241 767.0
HKD3_k127_9376711_1 His Kinase A (phosphoacceptor) domain K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 280.0
HKD3_k127_9376711_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008184 253.0
HKD3_k127_9376711_3 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000001206 170.0
HKD3_k127_9376711_4 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000001374 132.0
HKD3_k127_9376711_5 integral membrane protein - - - 0.00000000000000000000000002047 118.0
HKD3_k127_9376711_6 Putative peptidoglycan binding domain - - - 0.000000000000000144 89.0
HKD3_k127_9376711_7 Pentapeptide repeats (8 copies) - - - 0.000000005469 64.0
HKD3_k127_938043_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K15778 - 5.4.2.2,5.4.2.8 3.264e-248 776.0
HKD3_k127_938043_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 406.0
HKD3_k127_938043_2 Aspartyl protease K06985 - - 0.000000000000006868 78.0
HKD3_k127_938043_3 Phospholipid methyltransferase - - - 0.00000000000009479 77.0
HKD3_k127_9462093_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 557.0
HKD3_k127_9462093_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000004334 231.0
HKD3_k127_9462093_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000003899 48.0
HKD3_k127_9487681_0 Sarcosine oxidase, gamma subunit family K22087 - 1.5.99.5 0.00000000000000000000000000000000000000001075 162.0
HKD3_k127_9487681_1 - - - - 0.00000000000000000000000117 104.0
HKD3_k127_9487681_2 - - - - 0.000000000000000218 90.0
HKD3_k127_9487681_3 Aminomethyltransferase folate-binding domain K00302,K22086 - 1.5.3.1,1.5.99.5 0.00000000003473 63.0
HKD3_k127_9487681_4 - - - - 0.00000001602 57.0
HKD3_k127_9606989_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 380.0
HKD3_k127_9606989_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
HKD3_k127_9606989_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008048 268.0
HKD3_k127_9606989_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.000000000000000000000000000000000000000003368 156.0
HKD3_k127_9635278_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 461.0
HKD3_k127_9635278_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009233 259.0
HKD3_k127_9635278_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000004362 107.0
HKD3_k127_9647411_0 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000006411 216.0
HKD3_k127_9647411_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000002585 205.0
HKD3_k127_9647411_2 - - - - 0.0000005374 55.0