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Overview

ID MAG01850
Name HKD3_bin.33
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JADJWR01
Species
Assembly information
Completeness (%) 85.98
Contamination (%) 4.98
GC content (%) 69.0
N50 (bp) 30,564
Genome size (bp) 4,485,528

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4209

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1037422_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 3.531e-286 921.0
HKD3_k127_1037422_1 Histidine kinase K07646 - 2.7.13.3 1.923e-260 830.0
HKD3_k127_1037422_10 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 348.0
HKD3_k127_1037422_11 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 318.0
HKD3_k127_1037422_12 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 315.0
HKD3_k127_1037422_13 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 299.0
HKD3_k127_1037422_14 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
HKD3_k127_1037422_15 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 302.0
HKD3_k127_1037422_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004793 283.0
HKD3_k127_1037422_17 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001737 295.0
HKD3_k127_1037422_18 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007397 270.0
HKD3_k127_1037422_19 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000006991 242.0
HKD3_k127_1037422_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 5.321e-251 790.0
HKD3_k127_1037422_20 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000006271 230.0
HKD3_k127_1037422_21 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000002869 237.0
HKD3_k127_1037422_22 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000204 209.0
HKD3_k127_1037422_23 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
HKD3_k127_1037422_24 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000009402 192.0
HKD3_k127_1037422_25 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000000006728 143.0
HKD3_k127_1037422_26 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000004374 125.0
HKD3_k127_1037422_27 cytochrome K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000001333 89.0
HKD3_k127_1037422_28 COGs COG2361 conserved - - - 0.00000002468 65.0
HKD3_k127_1037422_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.68e-220 697.0
HKD3_k127_1037422_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 584.0
HKD3_k127_1037422_5 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 571.0
HKD3_k127_1037422_6 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 530.0
HKD3_k127_1037422_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 511.0
HKD3_k127_1037422_8 Sulfide dehydrogenase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 421.0
HKD3_k127_1037422_9 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 364.0
HKD3_k127_1051849_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 526.0
HKD3_k127_1051849_1 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 475.0
HKD3_k127_1051849_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 326.0
HKD3_k127_1051849_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 304.0
HKD3_k127_1051849_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007973 272.0
HKD3_k127_1051849_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000002156 194.0
HKD3_k127_1051849_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000141 176.0
HKD3_k127_1051849_7 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000008727 108.0
HKD3_k127_109559_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.402e-284 901.0
HKD3_k127_109559_1 AMP-binding enzyme K01895 - 6.2.1.1 9.692e-240 754.0
HKD3_k127_109559_10 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 297.0
HKD3_k127_109559_11 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
HKD3_k127_109559_12 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001811 282.0
HKD3_k127_109559_13 Nlpbdapx family lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001496 297.0
HKD3_k127_109559_14 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
HKD3_k127_109559_15 tellurite resistance protein - - - 0.0000000000000000000000000000000000000000000001683 188.0
HKD3_k127_109559_16 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000000000142 171.0
HKD3_k127_109559_17 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000006321 159.0
HKD3_k127_109559_18 - - - - 0.00000000000000000000000000000000000008594 156.0
HKD3_k127_109559_19 peptidyl-prolyl K03775 - 5.2.1.8 0.0000000000000000000000000000000001271 139.0
HKD3_k127_109559_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 1.635e-196 640.0
HKD3_k127_109559_20 - - - - 0.00000000001014 72.0
HKD3_k127_109559_3 TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 454.0
HKD3_k127_109559_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 421.0
HKD3_k127_109559_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 377.0
HKD3_k127_109559_6 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 389.0
HKD3_k127_109559_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 368.0
HKD3_k127_109559_8 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 354.0
HKD3_k127_109559_9 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 295.0
HKD3_k127_110649_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 464.0
HKD3_k127_110649_1 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 398.0
HKD3_k127_110649_2 Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 380.0
HKD3_k127_110649_3 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 329.0
HKD3_k127_110649_4 deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 303.0
HKD3_k127_110649_5 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000001006 76.0
HKD3_k127_110649_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.00000000000943 75.0
HKD3_k127_110649_7 P-aminobenzoate N-oxygenase AurF - - - 0.00005363 55.0
HKD3_k127_115135_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.613e-300 926.0
HKD3_k127_115135_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 574.0
HKD3_k127_115135_10 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001062 254.0
HKD3_k127_115135_11 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000007991 221.0
HKD3_k127_115135_12 PFAM BLUF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000005462 212.0
HKD3_k127_115135_14 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000001829 153.0
HKD3_k127_115135_15 Transposase DDE domain - - - 0.0000000000000000000000002839 111.0
HKD3_k127_115135_18 Signal peptidase, peptidase S26 K09647 - - 0.0000002692 60.0
HKD3_k127_115135_2 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 482.0
HKD3_k127_115135_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 435.0
HKD3_k127_115135_4 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 398.0
HKD3_k127_115135_5 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 396.0
HKD3_k127_115135_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 374.0
HKD3_k127_115135_7 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 323.0
HKD3_k127_115135_8 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000892 295.0
HKD3_k127_115135_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007877 267.0
HKD3_k127_1210023_0 - - - - 0.00000000000000000000000000000000000000000000000000000000001151 213.0
HKD3_k127_1210023_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000151 201.0
HKD3_k127_1210023_2 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000004568 156.0
HKD3_k127_1233244_0 Bacterial protein of unknown function (DUF839) K07093 - - 2.094e-256 802.0
HKD3_k127_1233244_1 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 5.578e-228 719.0
HKD3_k127_1233244_2 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
HKD3_k127_1233244_3 transcriptional regulator K03556 - - 0.0000000619 61.0
HKD3_k127_1236123_0 CoA binding domain K09181 - - 0.0 1022.0
HKD3_k127_1236123_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000003199 117.0
HKD3_k127_1236123_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000002439 60.0
HKD3_k127_1236926_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 410.0
HKD3_k127_1236926_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000007299 160.0
HKD3_k127_1236926_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000005845 144.0
HKD3_k127_1245250_0 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 337.0
HKD3_k127_1245250_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000004776 153.0
HKD3_k127_1245250_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000005493 85.0
HKD3_k127_1250846_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 409.0
HKD3_k127_1250846_1 Thioredoxin K05838 - - 0.0000000107 56.0
HKD3_k127_1260162_0 Site-specific recombinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 303.0
HKD3_k127_1260162_1 Catalyzes the sodium-dependent transport of glutamate - - - 0.00000000000000000000000000000000000000001046 165.0
HKD3_k127_1260779_0 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
HKD3_k127_1260779_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005542 244.0
HKD3_k127_1260779_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001527 213.0
HKD3_k127_1274264_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 336.0
HKD3_k127_1274264_1 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000001092 176.0
HKD3_k127_1277118_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 586.0
HKD3_k127_1277118_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 571.0
HKD3_k127_1277118_10 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 295.0
HKD3_k127_1277118_11 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000001258 209.0
HKD3_k127_1277118_12 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000006302 213.0
HKD3_k127_1277118_13 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000003673 188.0
HKD3_k127_1277118_14 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000144 153.0
HKD3_k127_1277118_15 Cupin domain - - - 0.0000000000000000000000000000000000002158 146.0
HKD3_k127_1277118_16 antitoxin K07172 - - 0.000000000000000000000000000008284 128.0
HKD3_k127_1277118_17 PGAP1-like protein - - - 0.0000000000000000000001327 109.0
HKD3_k127_1277118_18 Cytochrome c - - - 0.00000000001528 68.0
HKD3_k127_1277118_2 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 556.0
HKD3_k127_1277118_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 499.0
HKD3_k127_1277118_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 439.0
HKD3_k127_1277118_5 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 432.0
HKD3_k127_1277118_6 Periplasmic binding protein LacI transcriptional regulator K06145 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 425.0
HKD3_k127_1277118_7 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 413.0
HKD3_k127_1277118_8 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 344.0
HKD3_k127_1277118_9 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 298.0
HKD3_k127_127977_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 523.0
HKD3_k127_127977_1 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 447.0
HKD3_k127_127977_2 Flagellar motor protein K02557 - - 0.00000000000000000000000001678 109.0
HKD3_k127_1282756_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000002271 155.0
HKD3_k127_1282756_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000007985 146.0
HKD3_k127_1296829_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
HKD3_k127_1296829_1 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000002381 130.0
HKD3_k127_1296829_2 - - - - 0.0000000000000000000005373 106.0
HKD3_k127_1323255_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1471.0
HKD3_k127_1323255_1 Sulfatase - - - 0.0 1075.0
HKD3_k127_1323255_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 451.0
HKD3_k127_1323255_11 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 399.0
HKD3_k127_1323255_12 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 383.0
HKD3_k127_1323255_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 349.0
HKD3_k127_1323255_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003342 282.0
HKD3_k127_1323255_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
HKD3_k127_1323255_16 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003094 256.0
HKD3_k127_1323255_17 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000002292 237.0
HKD3_k127_1323255_18 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000001524 212.0
HKD3_k127_1323255_19 PspC domain - - - 0.000000000000000000000000003175 115.0
HKD3_k127_1323255_2 E3 component of 2-oxoglutarate dehydrogenase complex K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.042e-218 687.0
HKD3_k127_1323255_20 Glutathione S-transferase K11208 - - 0.00000000000000000000001007 116.0
HKD3_k127_1323255_21 response regulator - - - 0.00000000000000001766 90.0
HKD3_k127_1323255_22 Outer membrane protein beta-barrel domain - - - 0.00000000000006785 84.0
HKD3_k127_1323255_23 Protein of unknown function (DUF465) - - - 0.0000000002142 73.0
HKD3_k127_1323255_3 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.419e-212 677.0
HKD3_k127_1323255_4 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.856e-207 652.0
HKD3_k127_1323255_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 5.469e-195 616.0
HKD3_k127_1323255_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 603.0
HKD3_k127_1323255_7 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 592.0
HKD3_k127_1323255_8 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 559.0
HKD3_k127_1323255_9 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 512.0
HKD3_k127_1343280_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 1.299e-250 786.0
HKD3_k127_1343280_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.864e-212 672.0
HKD3_k127_1343280_10 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001346 257.0
HKD3_k127_1343280_11 peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000002499 172.0
HKD3_k127_1343280_12 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000009034 169.0
HKD3_k127_1343280_13 chain release factor K15034 - - 0.00000000000000000000000000000000000000000002065 167.0
HKD3_k127_1343280_14 Auxin binding protein - - - 0.00000000000000000000000000000000000000001659 156.0
HKD3_k127_1343280_15 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000004177 147.0
HKD3_k127_1343280_16 SMART Cold shock protein K03704 - - 0.000000000000000000000000000003389 123.0
HKD3_k127_1343280_17 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000000000000000007225 120.0
HKD3_k127_1343280_18 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000006685 119.0
HKD3_k127_1343280_19 - - - - 0.0000000000000000000009607 103.0
HKD3_k127_1343280_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 572.0
HKD3_k127_1343280_20 Ribbon-helix-helix protein, copG family - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000000002549 68.0
HKD3_k127_1343280_3 Trypsin K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 485.0
HKD3_k127_1343280_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 425.0
HKD3_k127_1343280_5 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 359.0
HKD3_k127_1343280_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 332.0
HKD3_k127_1343280_7 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 347.0
HKD3_k127_1343280_8 LysR substrate binding domain K18900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 313.0
HKD3_k127_1343280_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 294.0
HKD3_k127_1351631_0 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 449.0
HKD3_k127_1351631_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 381.0
HKD3_k127_1351631_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009776 350.0
HKD3_k127_1351631_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000002272 192.0
HKD3_k127_1361689_0 PFAM PHB de-polymerase domain protein K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 587.0
HKD3_k127_1361689_1 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 425.0
HKD3_k127_1361689_10 Cytochrome c - - - 0.000000000000000000004523 98.0
HKD3_k127_1361689_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 330.0
HKD3_k127_1361689_3 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
HKD3_k127_1361689_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
HKD3_k127_1361689_5 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000005224 244.0
HKD3_k127_1361689_6 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000003633 197.0
HKD3_k127_1361689_7 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000008936 188.0
HKD3_k127_1361689_8 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000001954 138.0
HKD3_k127_1361689_9 Cytochrome c class I - - - 0.00000000000000000000000000121 116.0
HKD3_k127_136267_0 Acyl transferase domain - - - 0.0 1775.0
HKD3_k127_136267_1 acyl-CoA dehydrogenase activity - - - 4.397e-213 675.0
HKD3_k127_136267_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 517.0
HKD3_k127_136267_3 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000004958 208.0
HKD3_k127_136267_4 Flavodoxin domain K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.000000000000000000000000000000000000000000000000000006311 196.0
HKD3_k127_136267_5 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000002386 139.0
HKD3_k127_1366406_0 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 486.0
HKD3_k127_1366406_1 Rhodanese Homology Domain K07390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 359.0
HKD3_k127_1366406_2 - - - - 0.000000005491 63.0
HKD3_k127_1390716_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 9.591e-308 972.0
HKD3_k127_1390716_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 628.0
HKD3_k127_1390716_10 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000001678 159.0
HKD3_k127_1390716_11 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000000000000000000007849 124.0
HKD3_k127_1390716_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.00000000000000000000000000001679 124.0
HKD3_k127_1390716_13 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000003851 121.0
HKD3_k127_1390716_14 Helix-turn-helix K21498 - - 0.0000000000000000000000364 111.0
HKD3_k127_1390716_15 Rubredoxin - - - 0.00000000000000000001979 96.0
HKD3_k127_1390716_16 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000003585 91.0
HKD3_k127_1390716_17 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000004698 74.0
HKD3_k127_1390716_2 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 455.0
HKD3_k127_1390716_3 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 407.0
HKD3_k127_1390716_4 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
HKD3_k127_1390716_5 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
HKD3_k127_1390716_6 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001252 275.0
HKD3_k127_1390716_7 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002436 251.0
HKD3_k127_1390716_8 hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000005995 211.0
HKD3_k127_1390716_9 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000000000000000000000000000000000002475 201.0
HKD3_k127_1424847_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004711 249.0
HKD3_k127_1424847_1 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000008029 79.0
HKD3_k127_1424847_2 PFAM FeoA family protein K04758 - - 0.0000000002855 64.0
HKD3_k127_1480215_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 2350.0
HKD3_k127_1480215_1 nitrite transporter K02575 - - 3.317e-311 959.0
HKD3_k127_1480215_10 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 339.0
HKD3_k127_1480215_11 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 319.0
HKD3_k127_1480215_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 305.0
HKD3_k127_1480215_13 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 298.0
HKD3_k127_1480215_14 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009475 280.0
HKD3_k127_1480215_15 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
HKD3_k127_1480215_16 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000001667 252.0
HKD3_k127_1480215_17 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000002837 227.0
HKD3_k127_1480215_18 protein conserved in bacteria K09950 - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
HKD3_k127_1480215_19 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
HKD3_k127_1480215_2 Major Facilitator Superfamily K02575 - - 4.542e-213 669.0
HKD3_k127_1480215_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000016 168.0
HKD3_k127_1480215_21 COG2076 Membrane transporters of cations and cationic drugs K11741 - - 0.0000000000000000000000000000000000004657 143.0
HKD3_k127_1480215_22 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001048 133.0
HKD3_k127_1480215_23 Protein of unknown function (DUF2796) - - - 0.000000000000000000000000000005166 130.0
HKD3_k127_1480215_24 Protein of unknown function (DUF1282) - - - 0.0000000000000000000000000006289 120.0
HKD3_k127_1480215_25 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000614 112.0
HKD3_k127_1480215_26 Respiratory nitrate reductase beta C-terminal K00371,K17051 - 1.7.5.1 0.0000000000000000000001292 98.0
HKD3_k127_1480215_27 Transposase - - - 0.000000009335 58.0
HKD3_k127_1480215_28 Sulfatase K01130 - 3.1.6.1 0.0000002636 57.0
HKD3_k127_1480215_3 o-acetylhomoserine K01740 - 2.5.1.49 1.103e-210 661.0
HKD3_k127_1480215_4 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 558.0
HKD3_k127_1480215_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 506.0
HKD3_k127_1480215_6 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 478.0
HKD3_k127_1480215_7 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 423.0
HKD3_k127_1480215_8 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 408.0
HKD3_k127_1480215_9 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 407.0
HKD3_k127_1498079_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 3.933e-273 851.0
HKD3_k127_1498079_1 PFAM ABC-1 domain protein K03688 - - 1.509e-242 764.0
HKD3_k127_1498079_10 Ribosomal protein L31 K02909 - - 0.0000000000000000000000000000002556 126.0
HKD3_k127_1498079_13 contains PIN domain - - - 0.00006939 52.0
HKD3_k127_1498079_2 PFAM extracellular solute-binding protein family 5 K02035 - - 5.917e-238 749.0
HKD3_k127_1498079_3 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 527.0
HKD3_k127_1498079_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 512.0
HKD3_k127_1498079_5 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 527.0
HKD3_k127_1498079_6 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 476.0
HKD3_k127_1498079_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 445.0
HKD3_k127_1498079_8 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 422.0
HKD3_k127_1498079_9 succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 400.0
HKD3_k127_1507640_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1031.0
HKD3_k127_1507640_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 8.196e-278 867.0
HKD3_k127_1507640_10 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 408.0
HKD3_k127_1507640_11 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 405.0
HKD3_k127_1507640_12 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 360.0
HKD3_k127_1507640_13 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 335.0
HKD3_k127_1507640_14 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 291.0
HKD3_k127_1507640_15 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001878 258.0
HKD3_k127_1507640_16 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000002639 238.0
HKD3_k127_1507640_17 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001971 243.0
HKD3_k127_1507640_18 TonB dependent receptor K16090 - - 0.000000000000000000000000000000000000000000000000000000000000000005652 236.0
HKD3_k127_1507640_19 PKHD-type hydroxylase K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000006991 237.0
HKD3_k127_1507640_2 PFAM AMP-dependent synthetase and ligase K00666 - - 1.271e-268 835.0
HKD3_k127_1507640_20 dehydrogenase subunit C K00113,K11473 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000002043 223.0
HKD3_k127_1507640_21 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000003433 229.0
HKD3_k127_1507640_22 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000002388 194.0
HKD3_k127_1507640_23 protein possibly involved in utilization of glycolate and propanediol K11477 - - 0.0000000000000000000000000000000000000000000000005247 183.0
HKD3_k127_1507640_24 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000003439 183.0
HKD3_k127_1507640_25 CHRD domain - - - 0.000000000000000000000000000000000000000000001442 171.0
HKD3_k127_1507640_26 NlpC/P60 family K13695,K19303 - - 0.00000000000000000000000000000000000001489 153.0
HKD3_k127_1507640_27 membrane - - - 0.0000000000000000000000000000000004016 146.0
HKD3_k127_1507640_28 PEP-CTERM motif - - - 0.0000000000000000006832 96.0
HKD3_k127_1507640_29 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors K07336 - - 0.00000000008027 65.0
HKD3_k127_1507640_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 573.0
HKD3_k127_1507640_4 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 504.0
HKD3_k127_1507640_5 transporter K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 513.0
HKD3_k127_1507640_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 473.0
HKD3_k127_1507640_7 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 467.0
HKD3_k127_1507640_8 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 452.0
HKD3_k127_1507640_9 Deacetylases including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 430.0
HKD3_k127_1522874_0 PFAM Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 403.0
HKD3_k127_1522874_1 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006929 257.0
HKD3_k127_1534652_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.477e-227 712.0
HKD3_k127_1534652_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 5.542e-209 665.0
HKD3_k127_1534652_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 301.0
HKD3_k127_1534652_3 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003523 234.0
HKD3_k127_1534652_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000101 211.0
HKD3_k127_1534652_5 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001823 198.0
HKD3_k127_1534652_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000007671 154.0
HKD3_k127_1534652_7 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000005564 148.0
HKD3_k127_1534652_8 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.0000000000000000000000000000001759 131.0
HKD3_k127_1554796_0 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 317.0
HKD3_k127_1554796_1 zinc-ribbon domain - - - 0.000000000000000000000000000000199 136.0
HKD3_k127_1554796_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000002971 76.0
HKD3_k127_1554897_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 308.0
HKD3_k127_1554897_1 Aldo/keto reductase family - - - 0.000000000000000000000008444 102.0
HKD3_k127_1554897_2 sulfatase - - - 0.00000000002303 70.0
HKD3_k127_1554897_3 Acetyltransferase (GNAT) domain - - - 0.000003373 51.0
HKD3_k127_1554897_4 Cysteine-rich CWC - - - 0.0002886 51.0
HKD3_k127_1583064_0 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 414.0
HKD3_k127_1583064_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000005696 216.0
HKD3_k127_1583064_2 Pfam Response regulator receiver - - - 0.00000000000000000000000006715 111.0
HKD3_k127_1583064_3 ATP-binding region ATPase domain protein - - - 0.00000000000000000007025 90.0
HKD3_k127_1636783_0 Hydantoinase/oxoprolinase - - - 1.349e-223 709.0
HKD3_k127_1636783_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 349.0
HKD3_k127_1636783_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000007269 180.0
HKD3_k127_1636783_3 Polysaccharide deacetylase - - - 0.0000000000856 62.0
HKD3_k127_164896_0 AMP-binding enzyme C-terminal domain K00666 - - 8.165e-240 754.0
HKD3_k127_164896_1 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 2.824e-227 715.0
HKD3_k127_164896_10 Cytochrome B561 - - - 0.000000000000000000000000000000000000000000000000000000000006453 228.0
HKD3_k127_164896_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
HKD3_k127_164896_12 transcriptional - - - 0.000000000000000000000000000000000000000000002353 175.0
HKD3_k127_164896_13 - - - - 0.00000000000000000000000000000000000000004877 156.0
HKD3_k127_164896_14 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000003076 148.0
HKD3_k127_164896_15 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000003648 144.0
HKD3_k127_164896_17 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000005122 53.0
HKD3_k127_164896_18 Peptidase propeptide and YPEB domain - - - 0.0007031 47.0
HKD3_k127_164896_2 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 594.0
HKD3_k127_164896_3 FAD binding K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 440.0
HKD3_k127_164896_4 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 430.0
HKD3_k127_164896_5 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 414.0
HKD3_k127_164896_6 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 317.0
HKD3_k127_164896_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02484,K07640,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 304.0
HKD3_k127_164896_8 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000005647 252.0
HKD3_k127_164896_9 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001566 241.0
HKD3_k127_1653824_0 exporters of the RND superfamily K07003 - - 0.0 1198.0
HKD3_k127_1653824_1 PFAM acyl-CoA dehydrogenase domain protein K20035 - - 3.74e-318 981.0
HKD3_k127_1653824_10 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 542.0
HKD3_k127_1653824_11 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 503.0
HKD3_k127_1653824_12 Taurine catabolism dioxygenase TauD, TfdA family K03119,K22303 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 449.0
HKD3_k127_1653824_13 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 451.0
HKD3_k127_1653824_14 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 409.0
HKD3_k127_1653824_15 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 389.0
HKD3_k127_1653824_16 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 360.0
HKD3_k127_1653824_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
HKD3_k127_1653824_18 Alpha beta hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 285.0
HKD3_k127_1653824_19 COG3293 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007143 282.0
HKD3_k127_1653824_2 AMP-binding enzyme C-terminal domain K02182,K20034 GO:0003674,GO:0003824,GO:0003996,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044464,GO:0071704 6.2.1.44,6.2.1.48 2.735e-310 955.0
HKD3_k127_1653824_20 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000007467 182.0
HKD3_k127_1653824_21 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000001423 134.0
HKD3_k127_1653824_22 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000000000000001433 122.0
HKD3_k127_1653824_23 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000001781 116.0
HKD3_k127_1653824_24 PFAM DoxX family protein K15977 - - 0.000000000000000000000000001662 123.0
HKD3_k127_1653824_25 - - - - 0.00000000000000000000003174 107.0
HKD3_k127_1653824_26 F420H(2)-dependent quinone reductase - - - 0.0000000000002894 83.0
HKD3_k127_1653824_28 - - - - 0.0000000000103 69.0
HKD3_k127_1653824_3 Protein of unknown function (DUF1329) - - - 2.774e-246 766.0
HKD3_k127_1653824_30 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0002209 47.0
HKD3_k127_1653824_4 Protein of unknown function (DUF1302) - - - 5.834e-230 754.0
HKD3_k127_1653824_5 beta-keto acid cleavage enzyme - - - 3.125e-195 631.0
HKD3_k127_1653824_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 590.0
HKD3_k127_1653824_7 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 548.0
HKD3_k127_1653824_8 alcohol dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 557.0
HKD3_k127_1653824_9 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 533.0
HKD3_k127_1672490_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.134e-295 928.0
HKD3_k127_1672490_1 Large family of predicted nucleotide-binding domains K07175 - - 3.683e-240 753.0
HKD3_k127_1672490_10 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 456.0
HKD3_k127_1672490_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 433.0
HKD3_k127_1672490_12 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 401.0
HKD3_k127_1672490_13 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 381.0
HKD3_k127_1672490_14 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 356.0
HKD3_k127_1672490_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 347.0
HKD3_k127_1672490_16 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003289 280.0
HKD3_k127_1672490_17 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000007311 274.0
HKD3_k127_1672490_18 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000051 252.0
HKD3_k127_1672490_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000001792 248.0
HKD3_k127_1672490_2 Aminotransferase K14261 - - 5.53e-220 690.0
HKD3_k127_1672490_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001509 238.0
HKD3_k127_1672490_21 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
HKD3_k127_1672490_22 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
HKD3_k127_1672490_23 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000144 203.0
HKD3_k127_1672490_24 Tetratricopeptide repeat K02656 - - 0.000000000000000000000000000000000000000000000000000005628 212.0
HKD3_k127_1672490_25 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000003619 189.0
HKD3_k127_1672490_26 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000003896 158.0
HKD3_k127_1672490_27 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000001801 152.0
HKD3_k127_1672490_28 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000002943 145.0
HKD3_k127_1672490_29 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000721 141.0
HKD3_k127_1672490_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.015e-211 674.0
HKD3_k127_1672490_30 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000001187 153.0
HKD3_k127_1672490_31 Lysin motif K06194 - - 0.0000000000000000002572 87.0
HKD3_k127_1672490_32 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000001844 89.0
HKD3_k127_1672490_33 protein conserved in bacteria K09937 - - 0.00000000001428 78.0
HKD3_k127_1672490_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.553e-205 647.0
HKD3_k127_1672490_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.813e-200 630.0
HKD3_k127_1672490_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 604.0
HKD3_k127_1672490_7 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 573.0
HKD3_k127_1672490_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 535.0
HKD3_k127_1672490_9 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 535.0
HKD3_k127_1715251_0 Belongs to the malate synthase family K01638 - 2.3.3.9 4.228e-295 910.0
HKD3_k127_1715251_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.859e-275 876.0
HKD3_k127_1715251_10 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 438.0
HKD3_k127_1715251_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 431.0
HKD3_k127_1715251_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 422.0
HKD3_k127_1715251_13 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 395.0
HKD3_k127_1715251_14 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 364.0
HKD3_k127_1715251_15 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 312.0
HKD3_k127_1715251_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 308.0
HKD3_k127_1715251_17 Protein of unknown function (DUF2863) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 316.0
HKD3_k127_1715251_18 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
HKD3_k127_1715251_19 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
HKD3_k127_1715251_2 Isocitrate lyase K01637 - 4.1.3.1 9.956e-250 774.0
HKD3_k127_1715251_20 negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000005556 250.0
HKD3_k127_1715251_21 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000006196 224.0
HKD3_k127_1715251_22 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000003645 228.0
HKD3_k127_1715251_23 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000959 235.0
HKD3_k127_1715251_24 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000001693 184.0
HKD3_k127_1715251_25 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000001228 191.0
HKD3_k127_1715251_26 rieske 2fe-2s - - - 0.0000000000000000000000000000000001087 143.0
HKD3_k127_1715251_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000001285 137.0
HKD3_k127_1715251_28 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006711 107.0
HKD3_k127_1715251_29 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000004475 111.0
HKD3_k127_1715251_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.965e-208 655.0
HKD3_k127_1715251_30 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000001006 76.0
HKD3_k127_1715251_31 Anti sigma-E protein RseA K03597 - - 0.00000000000001085 81.0
HKD3_k127_1715251_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.054e-200 630.0
HKD3_k127_1715251_5 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 557.0
HKD3_k127_1715251_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 556.0
HKD3_k127_1715251_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 529.0
HKD3_k127_1715251_8 Belongs to the 5'-nucleotidase family K01081,K17224 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 464.0
HKD3_k127_1715251_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 447.0
HKD3_k127_1734471_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.59e-244 761.0
HKD3_k127_1734471_1 BFD domain protein 2Fe-2S -binding domain protein K10815 - 1.4.99.5 1.133e-223 715.0
HKD3_k127_1734471_10 Helix-turn-helix domain - - - 0.000000000000000000000000000000000008808 142.0
HKD3_k127_1734471_11 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000005365 105.0
HKD3_k127_1734471_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 1.094e-199 628.0
HKD3_k127_1734471_3 peptidase M20 - - - 2.033e-198 623.0
HKD3_k127_1734471_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 577.0
HKD3_k127_1734471_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 381.0
HKD3_k127_1734471_6 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 316.0
HKD3_k127_1734471_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000008636 170.0
HKD3_k127_1734471_8 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000000000000000000000000000000834 171.0
HKD3_k127_1734471_9 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000000005058 162.0
HKD3_k127_1744783_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 568.0
HKD3_k127_1744783_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 556.0
HKD3_k127_1744783_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
HKD3_k127_1744783_3 Bacterial protein of unknown function (DUF839) K07093 - - 0.0000000000000000000000000000000004216 138.0
HKD3_k127_1744783_4 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.0000000174 56.0
HKD3_k127_1778079_0 - - - - 0.000000001592 66.0
HKD3_k127_1778079_1 GGDEF domain containing protein - - - 0.0001549 52.0
HKD3_k127_1786437_0 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000001163 137.0
HKD3_k127_1786437_1 - - - - 0.00000000000000002848 87.0
HKD3_k127_1846212_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 5.818e-248 772.0
HKD3_k127_1846212_1 ABC transporter transmembrane region K18889 - - 1.73e-234 764.0
HKD3_k127_1846212_2 ABC transporter transmembrane region K18890 - - 7.828e-231 732.0
HKD3_k127_1846212_3 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 312.0
HKD3_k127_1846212_4 NAD(P)H-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 306.0
HKD3_k127_1846212_5 SMART Rhodanese domain protein - - - 0.0002298 44.0
HKD3_k127_188709_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1076.0
HKD3_k127_188709_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0 1019.0
HKD3_k127_188709_10 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 462.0
HKD3_k127_188709_11 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 452.0
HKD3_k127_188709_12 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HKD3_k127_188709_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 368.0
HKD3_k127_188709_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
HKD3_k127_188709_15 - - - - 0.0000000000000000000000000000000000000000000000000000001332 210.0
HKD3_k127_188709_16 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000003364 214.0
HKD3_k127_188709_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000006735 215.0
HKD3_k127_188709_18 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000002362 210.0
HKD3_k127_188709_19 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000002704 184.0
HKD3_k127_188709_2 Alpha amylase, catalytic domain - - - 4.18e-287 892.0
HKD3_k127_188709_20 transcriptional regulator - - - 0.0000000000000000000000000000000000000002201 156.0
HKD3_k127_188709_21 PFAM MAPEG family - - - 0.000000000000000000000000000000000004057 152.0
HKD3_k127_188709_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000007507 143.0
HKD3_k127_188709_23 SMART Cold shock protein K03704 - - 0.0000000000000000000000000001161 116.0
HKD3_k127_188709_24 - - - - 0.000000000000000000001257 104.0
HKD3_k127_188709_25 nucleotidyltransferase activity - - - 0.000000000000002569 85.0
HKD3_k127_188709_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 2.593e-270 861.0
HKD3_k127_188709_4 ABC transporter transmembrane region K06147 - - 3.117e-262 824.0
HKD3_k127_188709_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 4.309e-261 829.0
HKD3_k127_188709_6 FtsX-like permease family K02004 - - 2.231e-212 687.0
HKD3_k127_188709_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 615.0
HKD3_k127_188709_8 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 544.0
HKD3_k127_188709_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 466.0
HKD3_k127_1890878_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 509.0
HKD3_k127_1890878_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 491.0
HKD3_k127_1890878_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 442.0
HKD3_k127_1890878_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 315.0
HKD3_k127_1890878_4 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000007802 201.0
HKD3_k127_1890878_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000001527 192.0
HKD3_k127_193788_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 327.0
HKD3_k127_193788_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000000006833 174.0
HKD3_k127_193788_2 response regulator - - - 0.0000000000000000000000000000000000000000000004913 176.0
HKD3_k127_193788_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000003074 134.0
HKD3_k127_193788_4 PFAM Outer membrane efflux protein - - - 0.0002916 46.0
HKD3_k127_201644_0 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005441 276.0
HKD3_k127_201644_1 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000329 236.0
HKD3_k127_201644_2 - - - - 0.0000000001521 70.0
HKD3_k127_201644_3 - - - - 0.0005419 53.0
HKD3_k127_2048675_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 618.0
HKD3_k127_2048675_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 544.0
HKD3_k127_2048675_10 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000004858 148.0
HKD3_k127_2048675_11 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.00000000000000000000000000000000000005991 143.0
HKD3_k127_2048675_12 universal stress protein - - - 0.0000000000000000000000000000000001337 137.0
HKD3_k127_2048675_13 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000174 147.0
HKD3_k127_2048675_14 Universal stress protein family - - - 0.00000000000000000000000000000008818 129.0
HKD3_k127_2048675_2 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 428.0
HKD3_k127_2048675_3 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 289.0
HKD3_k127_2048675_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002895 286.0
HKD3_k127_2048675_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 266.0
HKD3_k127_2048675_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002641 263.0
HKD3_k127_2048675_7 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
HKD3_k127_2048675_8 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000001487 241.0
HKD3_k127_2048675_9 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000001422 220.0
HKD3_k127_2053756_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 572.0
HKD3_k127_2053756_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 377.0
HKD3_k127_2053756_2 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 302.0
HKD3_k127_2098132_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 337.0
HKD3_k127_2098132_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
HKD3_k127_2098132_2 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000001725 177.0
HKD3_k127_2146198_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 346.0
HKD3_k127_2146198_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000001238 235.0
HKD3_k127_2239494_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
HKD3_k127_2239494_1 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007256 293.0
HKD3_k127_2239494_2 Dienelactone hydrolase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002718 243.0
HKD3_k127_223973_0 Circularly permuted ATP-grasp type 2 - - - 1.973e-243 758.0
HKD3_k127_223973_1 DHH family K07462 - - 2.246e-200 646.0
HKD3_k127_223973_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001821 259.0
HKD3_k127_223973_11 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000008701 192.0
HKD3_k127_223973_12 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000009268 135.0
HKD3_k127_223973_13 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000001933 134.0
HKD3_k127_223973_14 peptidoglycan binding K03642 - - 0.00000000000000000000000000226 117.0
HKD3_k127_223973_15 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000004062 82.0
HKD3_k127_223973_16 - - - - 0.00000005877 64.0
HKD3_k127_223973_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 537.0
HKD3_k127_223973_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 501.0
HKD3_k127_223973_4 Putative amidoligase enzyme (DUF2126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 458.0
HKD3_k127_223973_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 454.0
HKD3_k127_223973_6 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 467.0
HKD3_k127_223973_7 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 366.0
HKD3_k127_223973_8 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 314.0
HKD3_k127_223973_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 287.0
HKD3_k127_2290584_0 Transposase IS66 family - - - 1.576e-230 724.0
HKD3_k127_2290584_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000001564 229.0
HKD3_k127_2290584_2 Transposase K07483 - - 0.000000000000000000000000000002243 126.0
HKD3_k127_2290584_3 PFAM transposase, IS4 family protein - - - 0.00000000000000000009381 92.0
HKD3_k127_2290584_4 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00004342 47.0
HKD3_k127_241194_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 482.0
HKD3_k127_241194_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000007887 246.0
HKD3_k127_241194_2 SEC-C motif domain protein K07039 - - 0.000000000000000000000000000000000000004068 160.0
HKD3_k127_241194_3 4Fe-4S dicluster domain K18930 - - 0.0000000000000000000000000000000005214 132.0
HKD3_k127_241194_4 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000002474 122.0
HKD3_k127_241194_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000001043 122.0
HKD3_k127_241194_6 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000342 71.0
HKD3_k127_2438536_0 regulatory protein LuxR K03556,K21748 - - 0.0 1022.0
HKD3_k127_2438536_1 molybdopterin cofactor binding K08352 - 1.8.5.5 2.662e-312 972.0
HKD3_k127_2438536_10 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 390.0
HKD3_k127_2438536_11 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 313.0
HKD3_k127_2438536_12 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 319.0
HKD3_k127_2438536_13 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 312.0
HKD3_k127_2438536_14 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000003031 249.0
HKD3_k127_2438536_15 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
HKD3_k127_2438536_16 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HKD3_k127_2438536_17 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000001621 195.0
HKD3_k127_2438536_18 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000001999 192.0
HKD3_k127_2438536_19 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000002363 173.0
HKD3_k127_2438536_2 permease K07089 - - 1.255e-221 696.0
HKD3_k127_2438536_20 - K07112 - - 0.00000000000000000000000000000000000000000000113 171.0
HKD3_k127_2438536_21 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000001827 158.0
HKD3_k127_2438536_22 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000004222 165.0
HKD3_k127_2438536_23 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000001766 149.0
HKD3_k127_2438536_24 Thioredoxin domain - - - 0.000000000000000000000000000000000003758 138.0
HKD3_k127_2438536_25 Domain of unknown function (DUF1857) - - - 0.0000000000000000000000000006338 122.0
HKD3_k127_2438536_26 - - - - 0.00000000000000000000000001802 115.0
HKD3_k127_2438536_27 - - - - 0.00000000000000001978 90.0
HKD3_k127_2438536_28 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0000000002406 74.0
HKD3_k127_2438536_3 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 3.923e-216 681.0
HKD3_k127_2438536_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 2.383e-205 656.0
HKD3_k127_2438536_5 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 544.0
HKD3_k127_2438536_6 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 483.0
HKD3_k127_2438536_7 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 470.0
HKD3_k127_2438536_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 466.0
HKD3_k127_2438536_9 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 402.0
HKD3_k127_2442872_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1315.0
HKD3_k127_2442872_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1243.0
HKD3_k127_2442872_10 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 527.0
HKD3_k127_2442872_11 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 529.0
HKD3_k127_2442872_12 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 499.0
HKD3_k127_2442872_13 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 503.0
HKD3_k127_2442872_14 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 484.0
HKD3_k127_2442872_15 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 481.0
HKD3_k127_2442872_16 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 482.0
HKD3_k127_2442872_17 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 486.0
HKD3_k127_2442872_18 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 441.0
HKD3_k127_2442872_19 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 429.0
HKD3_k127_2442872_2 Protein of unknown function (DUF3141) - - - 9.153e-308 962.0
HKD3_k127_2442872_20 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 432.0
HKD3_k127_2442872_21 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 374.0
HKD3_k127_2442872_22 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 380.0
HKD3_k127_2442872_23 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 371.0
HKD3_k127_2442872_24 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 344.0
HKD3_k127_2442872_25 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
HKD3_k127_2442872_26 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 294.0
HKD3_k127_2442872_27 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
HKD3_k127_2442872_28 Serine hydrolase (FSH1) K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007179 285.0
HKD3_k127_2442872_29 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008152 251.0
HKD3_k127_2442872_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.186e-253 804.0
HKD3_k127_2442872_30 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HKD3_k127_2442872_31 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001268 246.0
HKD3_k127_2442872_32 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000001003 235.0
HKD3_k127_2442872_33 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000007836 216.0
HKD3_k127_2442872_34 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
HKD3_k127_2442872_35 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
HKD3_k127_2442872_36 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000007995 220.0
HKD3_k127_2442872_37 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000001809 206.0
HKD3_k127_2442872_38 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000004217 213.0
HKD3_k127_2442872_39 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000003138 198.0
HKD3_k127_2442872_4 TRAP dicarboxylate transporter, DctM subunit K03299 - - 7.049e-253 790.0
HKD3_k127_2442872_40 Yqey-like protein - - - 0.000000000000000000000000000000000000000000000000003581 188.0
HKD3_k127_2442872_41 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000001406 183.0
HKD3_k127_2442872_42 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.0000000000000000000000000000000000002153 153.0
HKD3_k127_2442872_43 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000006417 137.0
HKD3_k127_2442872_44 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000002322 135.0
HKD3_k127_2442872_45 lipid catabolic process - - - 0.000000000000000000000000000000002593 144.0
HKD3_k127_2442872_46 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000006511 128.0
HKD3_k127_2442872_47 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001251 117.0
HKD3_k127_2442872_48 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000242 109.0
HKD3_k127_2442872_49 PFAM Methyltransferase type 11 - - - 0.0000000000000000000001255 112.0
HKD3_k127_2442872_5 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 2.164e-206 649.0
HKD3_k127_2442872_50 - - - - 0.0000000000000000008849 89.0
HKD3_k127_2442872_51 cytochrome - - - 0.00000000000000002416 85.0
HKD3_k127_2442872_52 Belongs to the UPF0758 family K03630 - - 0.00000000000000004343 87.0
HKD3_k127_2442872_53 glycosyl transferase - - - 0.0001118 54.0
HKD3_k127_2442872_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 591.0
HKD3_k127_2442872_7 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 556.0
HKD3_k127_2442872_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 533.0
HKD3_k127_2442872_9 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 532.0
HKD3_k127_2451211_0 AcrB/AcrD/AcrF family - - - 0.0 1534.0
HKD3_k127_2451211_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1220.0
HKD3_k127_2451211_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 376.0
HKD3_k127_2451211_11 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 372.0
HKD3_k127_2451211_12 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 344.0
HKD3_k127_2451211_13 Domain of unknown function (DUF4372) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 341.0
HKD3_k127_2451211_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 285.0
HKD3_k127_2451211_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 290.0
HKD3_k127_2451211_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000007249 166.0
HKD3_k127_2451211_17 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000001539 166.0
HKD3_k127_2451211_18 epimerase dehydratase - - - 0.00000000000000000000000000000000000000006407 156.0
HKD3_k127_2451211_19 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000008893 141.0
HKD3_k127_2451211_2 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 0.0 1109.0
HKD3_k127_2451211_20 PFAM transposase, mutator type K07493 - - 0.000000000000000000003994 100.0
HKD3_k127_2451211_22 nucleoside diphosphate kinase K06140 - - 0.00000004137 61.0
HKD3_k127_2451211_23 transposase activity K07493 - - 0.0000747 47.0
HKD3_k127_2451211_24 - - - - 0.00007727 54.0
HKD3_k127_2451211_3 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 8.564e-300 944.0
HKD3_k127_2451211_4 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
HKD3_k127_2451211_5 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 477.0
HKD3_k127_2451211_6 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
HKD3_k127_2451211_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 462.0
HKD3_k127_2451211_8 ATPase activity, coupled to transmembrane movement of substances - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 406.0
HKD3_k127_2451211_9 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 369.0
HKD3_k127_2456745_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 387.0
HKD3_k127_2456745_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 255.0
HKD3_k127_2456745_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005943 248.0
HKD3_k127_2456745_3 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000001257 228.0
HKD3_k127_2456745_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000002027 220.0
HKD3_k127_2456745_5 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000000000001076 216.0
HKD3_k127_2456745_6 - - - - 0.00000000000000000000000000000000000000000000005098 178.0
HKD3_k127_2456745_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000003513 130.0
HKD3_k127_2456745_8 Gram-negative porin - - - 0.00014 49.0
HKD3_k127_2460332_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 608.0
HKD3_k127_2460332_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 586.0
HKD3_k127_2460332_2 OHCU decarboxylase K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 475.0
HKD3_k127_2460332_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 332.0
HKD3_k127_2460332_4 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
HKD3_k127_2460332_5 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000007589 147.0
HKD3_k127_2469792_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 524.0
HKD3_k127_2469792_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HKD3_k127_2469792_10 Protein of unknown function (DUF1439) - - - 0.0004289 50.0
HKD3_k127_2469792_2 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 325.0
HKD3_k127_2469792_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 324.0
HKD3_k127_2469792_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 303.0
HKD3_k127_2469792_5 OsmC-like protein - - - 0.000000000000000000000000000000004508 140.0
HKD3_k127_2469792_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.000000000000000000000000221 112.0
HKD3_k127_2469792_7 - - - - 0.00000000000000000004519 99.0
HKD3_k127_2469792_8 Type II transport protein GspH K08084 - - 0.00000000000000001363 94.0
HKD3_k127_247373_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1205.0
HKD3_k127_247373_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 616.0
HKD3_k127_2487443_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 271.0
HKD3_k127_2487443_1 viral genome integration into host DNA - - - 0.00000000000000000000000000000000000000000006147 170.0
HKD3_k127_2487443_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000229 112.0
HKD3_k127_2499459_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 315.0
HKD3_k127_2499459_1 Patatin phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002599 242.0
HKD3_k127_2499459_2 Domain of unknown function (DUF4396) - - - 0.0000000000000000000000000000000000000000000000000000001543 200.0
HKD3_k127_2499459_3 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000000000000000000000000000000000347 199.0
HKD3_k127_2499459_4 helix_turn_helix, mercury resistance K19591 - - 0.000000000000000000000000000000000000000000000005636 177.0
HKD3_k127_2499459_5 glutaminyl-tRNA K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000007475 178.0
HKD3_k127_2499459_6 Glycine zipper - - - 0.00000000000000000000000000000000000000000001643 168.0
HKD3_k127_2499459_7 TfoX N-terminal domain - - - 0.0000000000000000000000000004659 116.0
HKD3_k127_2499459_8 PepSY-associated TM region - - - 0.0000000000000001511 83.0
HKD3_k127_2499459_9 Protein of unknown function (DUF2917) - - - 0.00000001549 61.0
HKD3_k127_250182_0 Glucose / Sorbosone dehydrogenase - - - 4.248e-229 715.0
HKD3_k127_250182_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 592.0
HKD3_k127_250182_10 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000001528 169.0
HKD3_k127_250182_11 PFAM Cytochrome C K17230 - - 0.000000000000000000000000000001774 124.0
HKD3_k127_250182_12 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000226 117.0
HKD3_k127_250182_13 DUF167 - - - 0.00000000000000000006315 94.0
HKD3_k127_250182_2 TonB-dependent receptor plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 588.0
HKD3_k127_250182_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 512.0
HKD3_k127_250182_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 379.0
HKD3_k127_250182_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000064 273.0
HKD3_k127_250182_6 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009282 251.0
HKD3_k127_250182_7 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000002849 240.0
HKD3_k127_250182_8 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000000461 187.0
HKD3_k127_250182_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000001812 189.0
HKD3_k127_2501904_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 523.0
HKD3_k127_2501904_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 348.0
HKD3_k127_2502510_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 3.25e-231 724.0
HKD3_k127_2502510_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 523.0
HKD3_k127_2502510_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 470.0
HKD3_k127_2502510_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 459.0
HKD3_k127_2502510_4 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 341.0
HKD3_k127_2502510_5 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 328.0
HKD3_k127_2502510_6 Type II restriction enzyme, methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 254.0
HKD3_k127_2502510_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000967 210.0
HKD3_k127_2502510_8 Phosphopantetheine attachment site - - - 0.000000000000000002343 94.0
HKD3_k127_2502510_9 MacB-like periplasmic core domain K02004 - - 0.00000001915 55.0
HKD3_k127_2553880_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002272 282.0
HKD3_k127_2553880_1 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000003676 193.0
HKD3_k127_2553880_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000004057 125.0
HKD3_k127_2553880_3 - - - - 0.000000000000000000000003807 107.0
HKD3_k127_2553880_4 - - - - 0.0000000000001704 74.0
HKD3_k127_2577360_0 Sigma-54 interaction domain K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 521.0
HKD3_k127_2577360_1 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000002716 181.0
HKD3_k127_2577360_2 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.000000001482 61.0
HKD3_k127_2577793_0 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 570.0
HKD3_k127_2577793_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 464.0
HKD3_k127_2577793_2 Coenzyme A transferase K01031 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 363.0
HKD3_k127_2577793_3 Coenzyme A transferase K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 351.0
HKD3_k127_2579953_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 4.157e-199 636.0
HKD3_k127_2579953_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 355.0
HKD3_k127_2579953_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000006173 111.0
HKD3_k127_2585228_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1351.0
HKD3_k127_2585228_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.473e-227 713.0
HKD3_k127_2585228_10 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
HKD3_k127_2585228_11 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000000000348 159.0
HKD3_k127_2585228_12 Rhomboid family - - - 0.000000000000000003376 92.0
HKD3_k127_2585228_13 Subtilase family K14645 - - 0.00000000000000321 83.0
HKD3_k127_2585228_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.781e-217 684.0
HKD3_k127_2585228_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 593.0
HKD3_k127_2585228_4 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 586.0
HKD3_k127_2585228_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 516.0
HKD3_k127_2585228_6 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 409.0
HKD3_k127_2585228_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 406.0
HKD3_k127_2585228_8 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 376.0
HKD3_k127_2585228_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007274 273.0
HKD3_k127_2596464_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1771.0
HKD3_k127_2596464_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1662.0
HKD3_k127_2596464_10 extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 462.0
HKD3_k127_2596464_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 416.0
HKD3_k127_2596464_12 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 400.0
HKD3_k127_2596464_13 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 392.0
HKD3_k127_2596464_14 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 368.0
HKD3_k127_2596464_15 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 298.0
HKD3_k127_2596464_16 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000937 286.0
HKD3_k127_2596464_17 Protein of unknown function (DUF2848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002239 281.0
HKD3_k127_2596464_18 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000001134 241.0
HKD3_k127_2596464_19 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002175 242.0
HKD3_k127_2596464_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.457e-312 963.0
HKD3_k127_2596464_20 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000002546 231.0
HKD3_k127_2596464_21 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000002884 230.0
HKD3_k127_2596464_22 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000003169 211.0
HKD3_k127_2596464_23 Thioesterase superfamily K19222 - 3.1.2.28 0.00000000000000000000000000000000000000000000001925 174.0
HKD3_k127_2596464_24 COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - 0.0000000000000000000000000000000000000002474 156.0
HKD3_k127_2596464_25 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000003349 156.0
HKD3_k127_2596464_26 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000009116 147.0
HKD3_k127_2596464_27 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000001608 138.0
HKD3_k127_2596464_28 Alpha/beta hydrolase family - - - 0.000000000000000000000000000005956 130.0
HKD3_k127_2596464_29 BolA-like protein K05527 - - 0.0000000000000000000000001207 109.0
HKD3_k127_2596464_3 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 1.457e-272 849.0
HKD3_k127_2596464_30 - - - - 0.000000002484 59.0
HKD3_k127_2596464_4 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.263e-196 619.0
HKD3_k127_2596464_5 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 578.0
HKD3_k127_2596464_6 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 561.0
HKD3_k127_2596464_7 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 481.0
HKD3_k127_2596464_8 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 477.0
HKD3_k127_2596464_9 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 465.0
HKD3_k127_2598636_0 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 0.0 1043.0
HKD3_k127_2598636_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 577.0
HKD3_k127_2598636_10 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002177 239.0
HKD3_k127_2598636_11 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009279,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016409,GO:0016416,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044462,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.251 0.000000000000000000000000000000000000000000000000000000000000000001684 244.0
HKD3_k127_2598636_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000126 233.0
HKD3_k127_2598636_13 Urease beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000002884 214.0
HKD3_k127_2598636_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001066 230.0
HKD3_k127_2598636_15 nucleic acid-binding protein contains PIN domain K07062 - - 0.0000000000000000000000000000000000000000000000003553 183.0
HKD3_k127_2598636_16 Flagellar regulatory protein FleQ - - - 0.000000000000000000000000000000000000000000000004769 186.0
HKD3_k127_2598636_17 Urease, gamma subunit K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000126 175.0
HKD3_k127_2598636_18 plasmid maintenance system antidote protein K21498 - - 0.00000000000000000000000000000000000000000000001449 176.0
HKD3_k127_2598636_19 - - - - 0.0000000000000000000000000000000000000000001357 169.0
HKD3_k127_2598636_2 UreD urease accessory protein K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 455.0
HKD3_k127_2598636_20 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000000000002275 156.0
HKD3_k127_2598636_21 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000000000000000000000000002691 143.0
HKD3_k127_2598636_22 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000003379 122.0
HKD3_k127_2598636_23 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000769 100.0
HKD3_k127_2598636_24 Plasmid stability protein - - - 0.00000000000000009103 85.0
HKD3_k127_2598636_3 Sodium calcium K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 451.0
HKD3_k127_2598636_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 440.0
HKD3_k127_2598636_5 CobW/HypB/UreG, nucleotide-binding domain K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 369.0
HKD3_k127_2598636_6 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 339.0
HKD3_k127_2598636_7 UreF K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 314.0
HKD3_k127_2598636_8 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
HKD3_k127_2598636_9 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002585 267.0
HKD3_k127_260586_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 6.229e-229 749.0
HKD3_k127_260586_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 444.0
HKD3_k127_260586_2 Nitronate monooxygenase K00459 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 417.0
HKD3_k127_260586_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 362.0
HKD3_k127_260586_4 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000001399 178.0
HKD3_k127_260586_5 - - - - 0.000000000000000000000000000000000000000005704 159.0
HKD3_k127_261979_0 Peptidase family M20/M25/M40 - - - 0.0 1245.0
HKD3_k127_261979_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1115.0
HKD3_k127_261979_10 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000001519 190.0
HKD3_k127_261979_11 Belongs to the ParB family K03497 - - 0.000000000005396 69.0
HKD3_k127_261979_12 Belongs to the universal stress protein A family - - - 0.000000009971 69.0
HKD3_k127_261979_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 7.088e-237 752.0
HKD3_k127_261979_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 552.0
HKD3_k127_261979_4 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 546.0
HKD3_k127_261979_5 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 462.0
HKD3_k127_261979_6 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 363.0
HKD3_k127_261979_7 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 344.0
HKD3_k127_261979_8 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 307.0
HKD3_k127_261979_9 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009127 293.0
HKD3_k127_2628184_0 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 422.0
HKD3_k127_2628184_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002159 240.0
HKD3_k127_2628184_2 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000002879 211.0
HKD3_k127_2640098_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.149e-311 963.0
HKD3_k127_2640098_1 von Willebrand factor type A domain K03404 - 6.6.1.1 1.475e-195 629.0
HKD3_k127_2640098_10 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001749 283.0
HKD3_k127_2640098_11 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001074 266.0
HKD3_k127_2640098_12 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005253 255.0
HKD3_k127_2640098_13 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000003674 230.0
HKD3_k127_2640098_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000001005 82.0
HKD3_k127_2640098_2 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 507.0
HKD3_k127_2640098_3 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 503.0
HKD3_k127_2640098_4 DNA-binding transcription factor activity K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 391.0
HKD3_k127_2640098_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 387.0
HKD3_k127_2640098_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 376.0
HKD3_k127_2640098_7 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 373.0
HKD3_k127_2640098_8 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 324.0
HKD3_k127_2640098_9 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 311.0
HKD3_k127_2640510_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1026.0
HKD3_k127_2640510_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 5.232e-280 872.0
HKD3_k127_2640510_10 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000005468 187.0
HKD3_k127_2640510_11 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000000000002973 169.0
HKD3_k127_2640510_12 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000001273 177.0
HKD3_k127_2640510_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000009372 138.0
HKD3_k127_2640510_14 Iron-sulphur cluster assembly - - - 0.000000000000000000000000003202 119.0
HKD3_k127_2640510_15 nitrogen regulatory protein P-II - - - 0.000000000000000000000000003217 126.0
HKD3_k127_2640510_16 chorismate lyase activity - - - 0.0000000000000000000001621 104.0
HKD3_k127_2640510_17 RES domain - - - 0.00000002226 58.0
HKD3_k127_2640510_18 HNH endonuclease - - - 0.0000002003 59.0
HKD3_k127_2640510_19 PEP-CTERM motif - - - 0.0001963 51.0
HKD3_k127_2640510_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 6.135e-236 738.0
HKD3_k127_2640510_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.85e-229 713.0
HKD3_k127_2640510_4 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 593.0
HKD3_k127_2640510_5 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 353.0
HKD3_k127_2640510_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 263.0
HKD3_k127_2640510_7 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
HKD3_k127_2640510_8 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000005543 222.0
HKD3_k127_2640510_9 ferredoxin, 2Fe-2S K04755 - - 0.00000000000000000000000000000000000000000000000001983 186.0
HKD3_k127_2657723_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1463.0
HKD3_k127_2657723_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1296.0
HKD3_k127_2657723_10 RNB K01147 - 3.1.13.1 4.483e-206 661.0
HKD3_k127_2657723_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.479e-206 649.0
HKD3_k127_2657723_12 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.365e-203 648.0
HKD3_k127_2657723_13 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.16e-199 635.0
HKD3_k127_2657723_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 587.0
HKD3_k127_2657723_15 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 577.0
HKD3_k127_2657723_16 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 564.0
HKD3_k127_2657723_17 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 550.0
HKD3_k127_2657723_18 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 529.0
HKD3_k127_2657723_19 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 520.0
HKD3_k127_2657723_2 Malic enzyme K00029 - 1.1.1.40 0.0 1125.0
HKD3_k127_2657723_20 Sigma-54 interaction domain K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 516.0
HKD3_k127_2657723_21 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 484.0
HKD3_k127_2657723_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 482.0
HKD3_k127_2657723_23 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 446.0
HKD3_k127_2657723_24 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 452.0
HKD3_k127_2657723_25 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 424.0
HKD3_k127_2657723_26 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 400.0
HKD3_k127_2657723_27 SMART AAA ATPase K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 383.0
HKD3_k127_2657723_28 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 389.0
HKD3_k127_2657723_29 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 378.0
HKD3_k127_2657723_3 Belongs to the transketolase family K00615 - 2.2.1.1 4.907e-293 917.0
HKD3_k127_2657723_30 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 353.0
HKD3_k127_2657723_31 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 318.0
HKD3_k127_2657723_32 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 313.0
HKD3_k127_2657723_33 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 324.0
HKD3_k127_2657723_34 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 319.0
HKD3_k127_2657723_35 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 295.0
HKD3_k127_2657723_36 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003367 278.0
HKD3_k127_2657723_37 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005398 271.0
HKD3_k127_2657723_38 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003321 262.0
HKD3_k127_2657723_39 PFAM Lytic transglycosylase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002991 254.0
HKD3_k127_2657723_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.711e-281 874.0
HKD3_k127_2657723_40 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
HKD3_k127_2657723_41 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000002342 244.0
HKD3_k127_2657723_42 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
HKD3_k127_2657723_43 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000246 228.0
HKD3_k127_2657723_44 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000002096 222.0
HKD3_k127_2657723_45 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000048 219.0
HKD3_k127_2657723_46 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000001649 211.0
HKD3_k127_2657723_47 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000000319 216.0
HKD3_k127_2657723_48 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000001575 207.0
HKD3_k127_2657723_49 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000003036 204.0
HKD3_k127_2657723_5 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 4.136e-265 825.0
HKD3_k127_2657723_50 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000004605 199.0
HKD3_k127_2657723_51 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000003339 172.0
HKD3_k127_2657723_52 Redoxin domain protein - - - 0.00000000000000000000000000000000000000001955 166.0
HKD3_k127_2657723_53 YbaK prolyl-tRNA synthetase associated - - - 0.00000000000000000000000000000000000000005023 160.0
HKD3_k127_2657723_54 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000002157 153.0
HKD3_k127_2657723_55 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000009552 162.0
HKD3_k127_2657723_56 YGGT family K02221 - - 0.000000000000000000000000000000000000002153 155.0
HKD3_k127_2657723_57 ribonuclease K01167 - 3.1.27.3 0.0000000000000000000000000000000000006022 145.0
HKD3_k127_2657723_58 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000003744 138.0
HKD3_k127_2657723_59 mRNA catabolic process - - - 0.00000000000000000000000000000000004545 142.0
HKD3_k127_2657723_6 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 9.108e-254 786.0
HKD3_k127_2657723_60 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000005475 138.0
HKD3_k127_2657723_61 KTSC domain - - - 0.000000000000000000000000002248 116.0
HKD3_k127_2657723_62 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000002407 110.0
HKD3_k127_2657723_63 Barstar (Barnase inhibitor) - - - 0.0000000000000000001232 99.0
HKD3_k127_2657723_64 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000006159 71.0
HKD3_k127_2657723_65 - K06950 - - 0.00000000009397 74.0
HKD3_k127_2657723_66 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000001169 73.0
HKD3_k127_2657723_67 - - - - 0.0003134 46.0
HKD3_k127_2657723_7 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 2.283e-249 782.0
HKD3_k127_2657723_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.558e-214 679.0
HKD3_k127_2657723_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.56e-210 657.0
HKD3_k127_2695996_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 6.149e-296 913.0
HKD3_k127_2695996_1 PFAM aldehyde dehydrogenase K15514 - 1.2.1.77 4.834e-259 811.0
HKD3_k127_2695996_2 PFAM Extracellular ligand-binding receptor K01999 - - 8.603e-200 636.0
HKD3_k127_2695996_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 453.0
HKD3_k127_2695996_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 311.0
HKD3_k127_2695996_5 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 285.0
HKD3_k127_2695996_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000001522 79.0
HKD3_k127_2711614_0 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 6.031e-210 662.0
HKD3_k127_2711614_1 e3 binding domain K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 479.0
HKD3_k127_2711614_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000001788 242.0
HKD3_k127_2711614_3 PFAM glycosyl transferase family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001503 252.0
HKD3_k127_2711614_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000004127 203.0
HKD3_k127_2711614_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000001731 109.0
HKD3_k127_2711614_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000002306 88.0
HKD3_k127_2717501_0 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 320.0
HKD3_k127_2717501_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 267.0
HKD3_k127_2717501_2 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000003237 82.0
HKD3_k127_2718933_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 9.98e-259 806.0
HKD3_k127_2718933_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 506.0
HKD3_k127_2718933_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 486.0
HKD3_k127_2718933_3 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 451.0
HKD3_k127_2718933_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 346.0
HKD3_k127_2718933_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002796 253.0
HKD3_k127_2718933_6 prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000004515 237.0
HKD3_k127_2718933_7 membrane - - - 0.0000000000005246 72.0
HKD3_k127_2758940_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1139.0
HKD3_k127_2758940_1 Histidine kinase K02487,K06596 - - 0.0 1097.0
HKD3_k127_2758940_10 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 389.0
HKD3_k127_2758940_11 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 373.0
HKD3_k127_2758940_12 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 290.0
HKD3_k127_2758940_13 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002477 251.0
HKD3_k127_2758940_14 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000003466 233.0
HKD3_k127_2758940_15 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000198 231.0
HKD3_k127_2758940_16 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000005104 211.0
HKD3_k127_2758940_17 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000005183 194.0
HKD3_k127_2758940_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000601 172.0
HKD3_k127_2758940_19 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000001699 116.0
HKD3_k127_2758940_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.484e-288 891.0
HKD3_k127_2758940_20 Chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000001945 126.0
HKD3_k127_2758940_22 CRISPR_assoc - - - 0.0002275 51.0
HKD3_k127_2758940_3 LPXTG-motif cell wall anchor domain - - - 1.39e-261 844.0
HKD3_k127_2758940_4 PA domain - - - 1.596e-233 741.0
HKD3_k127_2758940_5 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 3.075e-209 657.0
HKD3_k127_2758940_6 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 538.0
HKD3_k127_2758940_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 527.0
HKD3_k127_2758940_8 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 499.0
HKD3_k127_2758940_9 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 440.0
HKD3_k127_2785121_0 Tripartite tricarboxylate transporter TctA family - - - 1.909e-225 708.0
HKD3_k127_2785121_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 534.0
HKD3_k127_2785121_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000005999 134.0
HKD3_k127_2785121_11 zeta toxin - - - 0.000000000000000000000000006429 120.0
HKD3_k127_2785121_12 Nucleotidyltransferase domain K07075 - - 0.00000000000000000002747 98.0
HKD3_k127_2785121_13 - - - - 0.0000000000000001602 88.0
HKD3_k127_2785121_14 Protein of unknown function DUF86 - - - 0.0000000000003428 75.0
HKD3_k127_2785121_15 zeta toxin - - - 0.00000000003614 70.0
HKD3_k127_2785121_16 Protein of unknown function (DUF2442) - - - 0.000000001951 62.0
HKD3_k127_2785121_17 Mut7-C RNAse domain - - - 0.00000004651 57.0
HKD3_k127_2785121_18 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00006785 48.0
HKD3_k127_2785121_19 - - - - 0.0001006 46.0
HKD3_k127_2785121_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 467.0
HKD3_k127_2785121_20 Protein of unknown function DUF86 - - - 0.0001484 47.0
HKD3_k127_2785121_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 432.0
HKD3_k127_2785121_4 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 345.0
HKD3_k127_2785121_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000004759 182.0
HKD3_k127_2785121_6 - - - - 0.00000000000000000000000000000000000000001735 156.0
HKD3_k127_2785121_7 regulator K18831 - - 0.00000000000000000000000000000000000000004755 156.0
HKD3_k127_2785121_8 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000002116 147.0
HKD3_k127_2785121_9 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000000008366 131.0
HKD3_k127_2808080_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1275.0
HKD3_k127_2808080_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.147e-316 978.0
HKD3_k127_2808080_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 6.811e-300 934.0
HKD3_k127_2808080_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 568.0
HKD3_k127_2808080_4 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000001401 211.0
HKD3_k127_283584_0 Pfam:HipA_N K07154 - 2.7.11.1 4.04e-219 685.0
HKD3_k127_283584_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.779e-216 690.0
HKD3_k127_283584_10 Histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 485.0
HKD3_k127_283584_11 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 436.0
HKD3_k127_283584_12 Phosphotransferase enzyme family K00899 - 2.7.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 414.0
HKD3_k127_283584_13 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 410.0
HKD3_k127_283584_14 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 379.0
HKD3_k127_283584_15 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 376.0
HKD3_k127_283584_16 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 371.0
HKD3_k127_283584_17 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
HKD3_k127_283584_18 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 333.0
HKD3_k127_283584_19 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 311.0
HKD3_k127_283584_2 Permeases of the major facilitator superfamily - - - 1.397e-206 648.0
HKD3_k127_283584_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
HKD3_k127_283584_21 Drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
HKD3_k127_283584_22 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006879 267.0
HKD3_k127_283584_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001035 259.0
HKD3_k127_283584_24 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003186 265.0
HKD3_k127_283584_25 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001944 246.0
HKD3_k127_283584_26 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000003259 204.0
HKD3_k127_283584_27 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000008015 170.0
HKD3_k127_283584_28 TIGRFAM phasin family protein - - - 0.0000000000000000000000000000000000000000003814 165.0
HKD3_k127_283584_29 - - - - 0.00000000000000000000000000000000000000001253 154.0
HKD3_k127_283584_3 ABC1 family - - - 1.073e-199 648.0
HKD3_k127_283584_30 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000004899 154.0
HKD3_k127_283584_31 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000001503 131.0
HKD3_k127_283584_32 MarR family - - - 0.0000000000000000000000000003566 119.0
HKD3_k127_283584_33 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000003432 83.0
HKD3_k127_283584_34 - - - - 0.00000000007717 63.0
HKD3_k127_283584_4 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 598.0
HKD3_k127_283584_5 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 597.0
HKD3_k127_283584_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
HKD3_k127_283584_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 535.0
HKD3_k127_283584_8 Benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 516.0
HKD3_k127_283584_9 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 507.0
HKD3_k127_2839994_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1683.0
HKD3_k127_2839994_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1155.0
HKD3_k127_2839994_10 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 601.0
HKD3_k127_2839994_11 C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 604.0
HKD3_k127_2839994_12 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 575.0
HKD3_k127_2839994_13 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 574.0
HKD3_k127_2839994_14 COG0569 K transport systems, NAD-binding component K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 567.0
HKD3_k127_2839994_15 ABC transporter, substrate-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 572.0
HKD3_k127_2839994_16 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 503.0
HKD3_k127_2839994_17 PFAM aromatic amino acid K00500 GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016714,GO:0055114 1.14.16.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 482.0
HKD3_k127_2839994_18 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 472.0
HKD3_k127_2839994_19 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 436.0
HKD3_k127_2839994_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.217e-253 810.0
HKD3_k127_2839994_20 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 430.0
HKD3_k127_2839994_21 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 415.0
HKD3_k127_2839994_22 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 417.0
HKD3_k127_2839994_23 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 407.0
HKD3_k127_2839994_24 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 392.0
HKD3_k127_2839994_25 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 372.0
HKD3_k127_2839994_26 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 351.0
HKD3_k127_2839994_27 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 353.0
HKD3_k127_2839994_28 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 344.0
HKD3_k127_2839994_29 Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 332.0
HKD3_k127_2839994_3 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 3.339e-243 760.0
HKD3_k127_2839994_30 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 347.0
HKD3_k127_2839994_31 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 325.0
HKD3_k127_2839994_32 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 316.0
HKD3_k127_2839994_33 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
HKD3_k127_2839994_34 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 311.0
HKD3_k127_2839994_35 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003808 283.0
HKD3_k127_2839994_36 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004535 262.0
HKD3_k127_2839994_37 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002538 242.0
HKD3_k127_2839994_38 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000003051 250.0
HKD3_k127_2839994_39 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
HKD3_k127_2839994_4 Transport of potassium into the cell K03549 - - 1.35e-228 724.0
HKD3_k127_2839994_40 Transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001609 244.0
HKD3_k127_2839994_41 PFAM Fructosamine - - - 0.00000000000000000000000000000000000000000000000000000000000000001408 235.0
HKD3_k127_2839994_42 - - - - 0.0000000000000000000000000000000000000000000000000000000000000006283 232.0
HKD3_k127_2839994_43 Nuclear protein SET K07117 - - 0.000000000000000000000000000000000000000000000000000000003757 211.0
HKD3_k127_2839994_44 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
HKD3_k127_2839994_45 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000007146 207.0
HKD3_k127_2839994_46 signal peptide protein - - - 0.000000000000000000000000000000000000000000000001181 181.0
HKD3_k127_2839994_47 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000002864 173.0
HKD3_k127_2839994_48 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000247 138.0
HKD3_k127_2839994_49 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000007458 137.0
HKD3_k127_2839994_5 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 3.737e-209 675.0
HKD3_k127_2839994_50 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.000000000000000000000000003434 118.0
HKD3_k127_2839994_51 Biotin-requiring enzyme - - - 0.00000000000000000000000003631 119.0
HKD3_k127_2839994_52 Protein of unknown function (DUF2905) - - - 0.00000000000000000000001696 107.0
HKD3_k127_2839994_53 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.00000000000000000000002089 117.0
HKD3_k127_2839994_54 Protein of unknown function (DUF3567) - - - 0.0000000000000000005553 100.0
HKD3_k127_2839994_55 Acetyltransferase (GNAT) domain - - - 0.00000000000000001291 98.0
HKD3_k127_2839994_56 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000007034 84.0
HKD3_k127_2839994_57 Putative addiction module component - - - 0.00000000000004272 76.0
HKD3_k127_2839994_58 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000001529 50.0
HKD3_k127_2839994_59 cobalamin synthesis protein, P47K - GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0008270,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0001126 49.0
HKD3_k127_2839994_6 Protein of unknown function (DUF2867) - - - 1.866e-196 630.0
HKD3_k127_2839994_60 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0002309 48.0
HKD3_k127_2839994_7 B12 binding domain K00548 - 2.1.1.13 6.455e-196 621.0
HKD3_k127_2839994_8 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 627.0
HKD3_k127_2839994_9 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 619.0
HKD3_k127_2850896_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1159.0
HKD3_k127_2850896_1 Sulfite reductase K00381 - 1.8.1.2 3.683e-242 762.0
HKD3_k127_2850896_10 conserved protein ucp030820 - - - 0.000000000000000000000000000000005572 148.0
HKD3_k127_2850896_11 Universal stress protein family - - - 0.000000000000000000000000000000501 127.0
HKD3_k127_2850896_12 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000001028 107.0
HKD3_k127_2850896_13 Rhodanese Homology Domain - - - 0.000000000000000000000826 102.0
HKD3_k127_2850896_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 497.0
HKD3_k127_2850896_3 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 490.0
HKD3_k127_2850896_4 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 477.0
HKD3_k127_2850896_5 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 371.0
HKD3_k127_2850896_6 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 323.0
HKD3_k127_2850896_7 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
HKD3_k127_2850896_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000001761 279.0
HKD3_k127_2850896_9 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
HKD3_k127_2855911_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 580.0
HKD3_k127_2855911_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 450.0
HKD3_k127_2855911_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 395.0
HKD3_k127_2855911_3 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000001708 132.0
HKD3_k127_2855911_4 NHL repeat - - - 0.0000001668 57.0
HKD3_k127_2874976_0 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
HKD3_k127_2874976_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000001229 88.0
HKD3_k127_2874976_2 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000008978 54.0
HKD3_k127_287574_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1344.0
HKD3_k127_287574_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.635e-246 792.0
HKD3_k127_287574_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 460.0
HKD3_k127_287574_11 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 401.0
HKD3_k127_287574_12 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 337.0
HKD3_k127_287574_13 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 342.0
HKD3_k127_287574_14 SapC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
HKD3_k127_287574_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000001402 253.0
HKD3_k127_287574_16 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000003014 229.0
HKD3_k127_287574_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000003506 225.0
HKD3_k127_287574_18 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000005029 178.0
HKD3_k127_287574_19 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000002216 160.0
HKD3_k127_287574_2 Peptidase, M50 family - - - 2.061e-209 679.0
HKD3_k127_287574_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 582.0
HKD3_k127_287574_4 GAF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 572.0
HKD3_k127_287574_5 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 547.0
HKD3_k127_287574_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 526.0
HKD3_k127_287574_7 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 496.0
HKD3_k127_287574_8 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 498.0
HKD3_k127_287574_9 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 477.0
HKD3_k127_2882870_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.632e-276 859.0
HKD3_k127_2882870_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 557.0
HKD3_k127_2882870_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000002249 145.0
HKD3_k127_2886901_0 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 537.0
HKD3_k127_2886901_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 520.0
HKD3_k127_2886901_10 of the drug metabolite transporter (DMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001721 275.0
HKD3_k127_2886901_11 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004062 288.0
HKD3_k127_2886901_12 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001367 282.0
HKD3_k127_2886901_13 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001781 256.0
HKD3_k127_2886901_14 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000001594 179.0
HKD3_k127_2886901_15 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000000000000000000000163 144.0
HKD3_k127_2886901_16 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000008349 136.0
HKD3_k127_2886901_17 Copper resistance protein D - - - 0.0000000000000000000000001041 120.0
HKD3_k127_2886901_18 acetyltransferase - - - 0.00000000000000000000004909 104.0
HKD3_k127_2886901_19 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 0.000000000000000000002863 93.0
HKD3_k127_2886901_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 434.0
HKD3_k127_2886901_20 PFAM NHL repeat containing protein - - - 0.0000000000000000002161 98.0
HKD3_k127_2886901_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000001959 94.0
HKD3_k127_2886901_22 phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - 0.0000000002552 69.0
HKD3_k127_2886901_3 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 421.0
HKD3_k127_2886901_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 410.0
HKD3_k127_2886901_5 GTP-binding protein K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 387.0
HKD3_k127_2886901_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 321.0
HKD3_k127_2886901_7 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 317.0
HKD3_k127_2886901_8 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 287.0
HKD3_k127_2886901_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 278.0
HKD3_k127_2904454_0 Biopolymer transporter ExbB K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 341.0
HKD3_k127_2904454_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000374 233.0
HKD3_k127_2904454_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000000000000000008644 202.0
HKD3_k127_2904454_3 Biopolymer K03559 - - 0.0000000000000000000000000000102 126.0
HKD3_k127_2935906_0 Dehydrogenase E1 component K00166 - 1.2.4.4 2.164e-196 622.0
HKD3_k127_2935906_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00167 - 1.2.4.4 0.000000000000007452 75.0
HKD3_k127_2937425_0 acyl-CoA dehydrogenase K09456 - - 3.916e-301 932.0
HKD3_k127_2937425_1 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 9.131e-239 753.0
HKD3_k127_2937425_10 - - - - 0.00000000002267 72.0
HKD3_k127_2937425_12 - - - - 0.00001025 51.0
HKD3_k127_2937425_13 - - - - 0.00001309 57.0
HKD3_k127_2937425_14 helicase K08282 - 2.7.11.1 0.00008728 52.0
HKD3_k127_2937425_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 577.0
HKD3_k127_2937425_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 514.0
HKD3_k127_2937425_4 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 317.0
HKD3_k127_2937425_5 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 305.0
HKD3_k127_2937425_6 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
HKD3_k127_2937425_7 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000005121 201.0
HKD3_k127_2937425_8 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000002014 179.0
HKD3_k127_2937425_9 - - - - 0.00000000000000000000000001252 115.0
HKD3_k127_2938636_0 LysR substrate binding domain - - - 0.000000000008638 70.0
HKD3_k127_2938636_1 PFAM Peptidase M11 gametolysin - - - 0.000002263 59.0
HKD3_k127_2940326_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 451.0
HKD3_k127_2940326_1 sodium bile acid symporter family K03453 - - 0.000000000000000005705 94.0
HKD3_k127_2941230_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 341.0
HKD3_k127_2941230_1 O-Methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003636 276.0
HKD3_k127_2941230_2 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008891 245.0
HKD3_k127_2941230_3 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000004886 156.0
HKD3_k127_2941230_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000009724 121.0
HKD3_k127_2945409_0 AcrB/AcrD/AcrF family - - - 0.0 1315.0
HKD3_k127_2945409_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.574e-212 687.0
HKD3_k127_2945409_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000144 229.0
HKD3_k127_2945409_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000001017 185.0
HKD3_k127_2945409_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000125 130.0
HKD3_k127_2959202_0 FAD dependent oxidoreductase central domain - - - 0.0 1293.0
HKD3_k127_2959202_1 carboxylase K01969 - 6.4.1.4 6.939e-286 908.0
HKD3_k127_2959202_10 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 529.0
HKD3_k127_2959202_11 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 492.0
HKD3_k127_2959202_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 467.0
HKD3_k127_2959202_13 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 462.0
HKD3_k127_2959202_14 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 446.0
HKD3_k127_2959202_15 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 406.0
HKD3_k127_2959202_16 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 413.0
HKD3_k127_2959202_17 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 394.0
HKD3_k127_2959202_18 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 371.0
HKD3_k127_2959202_19 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 346.0
HKD3_k127_2959202_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 4.778e-272 849.0
HKD3_k127_2959202_20 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 313.0
HKD3_k127_2959202_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 304.0
HKD3_k127_2959202_22 Phosphoglycerate dehydrogenase and related dehydrogenases K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000007816 278.0
HKD3_k127_2959202_23 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001063 260.0
HKD3_k127_2959202_24 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002302 245.0
HKD3_k127_2959202_25 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004809 256.0
HKD3_k127_2959202_26 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000102 239.0
HKD3_k127_2959202_27 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001891 238.0
HKD3_k127_2959202_28 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000008879 219.0
HKD3_k127_2959202_29 Methyltransferase domain K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000003761 213.0
HKD3_k127_2959202_3 carboxylase K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.3,6.4.1.4 1.402e-265 833.0
HKD3_k127_2959202_30 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003174 215.0
HKD3_k127_2959202_31 LemA family K03744 - - 0.0000000000000000000000000000000000000000005382 164.0
HKD3_k127_2959202_32 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000512 164.0
HKD3_k127_2959202_33 Small Multidrug Resistance protein K03297 - - 0.0000000000000000000000000000000000000006979 152.0
HKD3_k127_2959202_34 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000002881 154.0
HKD3_k127_2959202_35 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000004074 160.0
HKD3_k127_2959202_36 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000001543 140.0
HKD3_k127_2959202_37 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000000000000000000001803 141.0
HKD3_k127_2959202_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000123 120.0
HKD3_k127_2959202_39 - - - - 0.0000000000000000000000001462 110.0
HKD3_k127_2959202_4 Histidine kinase-like ATPases - - - 1.931e-214 705.0
HKD3_k127_2959202_40 cyclic nucleotide binding K10914 - - 0.000000000000000000000002951 119.0
HKD3_k127_2959202_41 Small Multidrug Resistance protein - - - 0.00000000000000000000005185 109.0
HKD3_k127_2959202_42 PLD-like domain - - - 0.000000000000000001675 93.0
HKD3_k127_2959202_5 Amidohydrolase family - - - 3.076e-214 689.0
HKD3_k127_2959202_6 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 4.876e-202 665.0
HKD3_k127_2959202_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 573.0
HKD3_k127_2959202_8 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 539.0
HKD3_k127_2959202_9 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 536.0
HKD3_k127_2966647_0 mechanosensitive ion channel K05802 - - 5.771e-248 794.0
HKD3_k127_2966647_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 4.185e-204 646.0
HKD3_k127_2966647_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000001625 175.0
HKD3_k127_2966647_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000006174 104.0
HKD3_k127_2966647_4 Outer membrane lipoprotein K06077 - - 0.0000000000000001379 88.0
HKD3_k127_2966647_5 Radical SAM superfamily K06871 - - 0.0000000000000002486 81.0
HKD3_k127_3060019_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 8.338e-246 768.0
HKD3_k127_3060019_1 von Willebrand factor, type A K07114 - - 2.212e-216 693.0
HKD3_k127_3060019_10 - - - - 0.000000000000000000000000000000000003846 154.0
HKD3_k127_3060019_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000008294 137.0
HKD3_k127_3060019_12 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000009787 108.0
HKD3_k127_3060019_13 - - - - 0.00000000000000000791 93.0
HKD3_k127_3060019_14 Domain of unknown function (DUF1840) - - - 0.0000000000000002096 83.0
HKD3_k127_3060019_15 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000005211 74.0
HKD3_k127_3060019_16 30S ribosomal protein Thx K19033 - - 0.0001485 45.0
HKD3_k127_3060019_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 587.0
HKD3_k127_3060019_3 C4-dicarboxylate ABC transporter K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 505.0
HKD3_k127_3060019_4 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 426.0
HKD3_k127_3060019_5 Two component transcriptional regulator K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001466 281.0
HKD3_k127_3060019_6 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000000003141 203.0
HKD3_k127_3060019_7 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000001319 200.0
HKD3_k127_3060019_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000004338 176.0
HKD3_k127_3060019_9 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000005806 166.0
HKD3_k127_3156631_0 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000001949 198.0
HKD3_k127_3156631_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001589 189.0
HKD3_k127_3156631_2 LysE type translocator - - - 0.00000000000000000000000000000000000000000001035 185.0
HKD3_k127_3156631_3 Metal-dependent hydrolase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.00000000000000000000000000006511 128.0
HKD3_k127_3156631_4 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.00000000000000000006881 88.0
HKD3_k127_3174455_0 HD domain - - - 7.096e-265 848.0
HKD3_k127_3174455_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.547e-235 747.0
HKD3_k127_3174455_10 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 286.0
HKD3_k127_3174455_11 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
HKD3_k127_3174455_12 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000001101 249.0
HKD3_k127_3174455_13 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000004422 216.0
HKD3_k127_3174455_14 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000000000015 213.0
HKD3_k127_3174455_15 Sugar (and other) transporter - - - 0.000000000000000000000000000000009527 134.0
HKD3_k127_3174455_16 Belongs to the transcriptional regulatory Fis family K03557 - - 0.00000000000005718 85.0
HKD3_k127_3174455_17 SnoaL-like domain - - - 0.0000000000000668 84.0
HKD3_k127_3174455_18 PFAM SpoVT AbrB K07172,K18829 - - 0.000000008228 59.0
HKD3_k127_3174455_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 624.0
HKD3_k127_3174455_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 545.0
HKD3_k127_3174455_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 453.0
HKD3_k127_3174455_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 446.0
HKD3_k127_3174455_6 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 445.0
HKD3_k127_3174455_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 449.0
HKD3_k127_3174455_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 364.0
HKD3_k127_3174455_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001994 278.0
HKD3_k127_3176843_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 357.0
HKD3_k127_3176843_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 319.0
HKD3_k127_322816_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.226e-252 800.0
HKD3_k127_322816_1 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 439.0
HKD3_k127_322816_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 414.0
HKD3_k127_322816_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000819 241.0
HKD3_k127_322816_4 COG0500 SAM-dependent methyltransferases - - - 0.00000000000002302 76.0
HKD3_k127_322816_5 Protein of unknown function (DUF3429) - - - 0.000000000007607 76.0
HKD3_k127_3262486_0 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000000492 202.0
HKD3_k127_3262486_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000003825 170.0
HKD3_k127_3262486_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000005609 159.0
HKD3_k127_3262486_3 Gram-negative porin - - - 0.00000000000000009558 87.0
HKD3_k127_338703_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 560.0
HKD3_k127_338703_1 Predicted membrane protein (DUF2142) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 515.0
HKD3_k127_338703_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 472.0
HKD3_k127_338703_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 485.0
HKD3_k127_338703_4 Outer membrane efflux protein K12538 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001648 277.0
HKD3_k127_338703_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000007423 226.0
HKD3_k127_338703_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000008691 213.0
HKD3_k127_338703_7 Involved in the tonB-independent uptake of proteins K01406,K03641,K21449 - 3.4.24.40 0.00000000000000000000007622 109.0
HKD3_k127_338703_8 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537,K16300 - - 0.00000007531 53.0
HKD3_k127_3393699_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1583.0
HKD3_k127_3393699_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 474.0
HKD3_k127_3393699_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 306.0
HKD3_k127_3393699_3 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005116 273.0
HKD3_k127_3394889_0 alkaline phosphatase K07093 - - 2.281e-280 883.0
HKD3_k127_3394889_1 Highly conserved protein containing a thioredoxin domain K06888 - - 5.793e-245 774.0
HKD3_k127_3394889_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
HKD3_k127_3394889_11 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 311.0
HKD3_k127_3394889_12 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 307.0
HKD3_k127_3394889_13 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
HKD3_k127_3394889_14 RES domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
HKD3_k127_3394889_15 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000007477 239.0
HKD3_k127_3394889_16 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000001704 229.0
HKD3_k127_3394889_17 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000002317 196.0
HKD3_k127_3394889_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000001381 192.0
HKD3_k127_3394889_19 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000018 199.0
HKD3_k127_3394889_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 588.0
HKD3_k127_3394889_20 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000001878 178.0
HKD3_k127_3394889_21 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000001018 180.0
HKD3_k127_3394889_22 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000000000000001771 180.0
HKD3_k127_3394889_23 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000001819 180.0
HKD3_k127_3394889_24 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000004946 120.0
HKD3_k127_3394889_25 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000006326 125.0
HKD3_k127_3394889_26 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000003638 113.0
HKD3_k127_3394889_27 - - - - 0.00000000000000000004293 96.0
HKD3_k127_3394889_28 - - - - 0.00000000000000006207 94.0
HKD3_k127_3394889_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 572.0
HKD3_k127_3394889_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 561.0
HKD3_k127_3394889_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 515.0
HKD3_k127_3394889_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 496.0
HKD3_k127_3394889_7 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 422.0
HKD3_k127_3394889_8 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 376.0
HKD3_k127_3394889_9 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 378.0
HKD3_k127_3412462_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 6.873e-298 929.0
HKD3_k127_3412462_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 8.77e-253 793.0
HKD3_k127_3412462_10 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000414 198.0
HKD3_k127_3412462_11 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000003349 198.0
HKD3_k127_3412462_12 protein conserved in cyanobacteria - - - 0.0000000000000008138 91.0
HKD3_k127_3412462_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.717e-235 741.0
HKD3_k127_3412462_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 592.0
HKD3_k127_3412462_4 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 590.0
HKD3_k127_3412462_5 Phosphoribulokinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 494.0
HKD3_k127_3412462_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 502.0
HKD3_k127_3412462_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 458.0
HKD3_k127_3412462_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001204 277.0
HKD3_k127_3412462_9 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003771 261.0
HKD3_k127_3485484_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 6.632e-227 719.0
HKD3_k127_3485484_1 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001419 276.0
HKD3_k127_3485484_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000002111 238.0
HKD3_k127_3485484_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000005034 143.0
HKD3_k127_355061_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000003546 101.0
HKD3_k127_355061_1 Bacterial Ig-like domain 2 - - - 0.000006289 58.0
HKD3_k127_3654218_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 8.287e-295 923.0
HKD3_k127_3654218_1 Patatin-like phospholipase K07001 - - 8.26e-272 862.0
HKD3_k127_3654218_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 426.0
HKD3_k127_3654218_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 419.0
HKD3_k127_3654218_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 355.0
HKD3_k127_3654218_5 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000005198 248.0
HKD3_k127_3665416_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.119e-251 789.0
HKD3_k127_3665416_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 1.231e-202 636.0
HKD3_k127_3665416_10 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 281.0
HKD3_k127_3665416_11 Psort location Cytoplasmic, score K07505 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002223 298.0
HKD3_k127_3665416_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005545 274.0
HKD3_k127_3665416_13 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
HKD3_k127_3665416_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000009781 243.0
HKD3_k127_3665416_15 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
HKD3_k127_3665416_16 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000000000002536 166.0
HKD3_k127_3665416_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000253 149.0
HKD3_k127_3665416_18 Protein of unknown function (DUF3987) - - - 0.00000000000000000000000000000000008058 154.0
HKD3_k127_3665416_19 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000008257 110.0
HKD3_k127_3665416_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 466.0
HKD3_k127_3665416_21 Phage capsid family - - - 0.0000002842 63.0
HKD3_k127_3665416_3 Terminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 440.0
HKD3_k127_3665416_4 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 393.0
HKD3_k127_3665416_5 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 378.0
HKD3_k127_3665416_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 373.0
HKD3_k127_3665416_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 349.0
HKD3_k127_3665416_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 357.0
HKD3_k127_3665416_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
HKD3_k127_3677680_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 334.0
HKD3_k127_3677680_1 mechanosensitive ion channel K03442,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 334.0
HKD3_k127_3677680_2 von Willebrand factor type A domain K07114 - - 0.00000000000000009645 87.0
HKD3_k127_3685664_0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 441.0
HKD3_k127_3685664_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000001588 203.0
HKD3_k127_3688234_0 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 8.226e-196 638.0
HKD3_k127_3688234_1 Major Facilitator Superfamily - - - 0.00000000000006467 72.0
HKD3_k127_3696883_0 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003565 249.0
HKD3_k127_3696883_1 Ferredoxin - - - 0.0000000000000000000000000000000000000000000008379 168.0
HKD3_k127_3696883_2 VanZ like family - - - 0.000000000000000000000000000000000000003476 155.0
HKD3_k127_3696883_3 - - - - 0.000000000613 66.0
HKD3_k127_3697594_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 2.032e-222 699.0
HKD3_k127_3697594_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000009311 246.0
HKD3_k127_3697594_2 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000004663 136.0
HKD3_k127_3697594_3 NapD protein K02570 - - 0.00000003706 65.0
HKD3_k127_3711729_0 carboxylase K01969 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 520.0
HKD3_k127_3711729_1 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 449.0
HKD3_k127_3711729_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
HKD3_k127_3711729_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000133 170.0
HKD3_k127_3717615_0 AMP-binding enzyme C-terminal domain K18661 - - 8.587e-204 647.0
HKD3_k127_3717615_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 438.0
HKD3_k127_3717615_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 396.0
HKD3_k127_3717615_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 329.0
HKD3_k127_3717615_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
HKD3_k127_3717615_5 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000005116 224.0
HKD3_k127_3717615_6 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000675 201.0
HKD3_k127_3746462_0 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 432.0
HKD3_k127_3746462_1 OmpW family K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002274 177.0
HKD3_k127_3790530_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1633.0
HKD3_k127_3790530_1 Type II restriction enzyme, methylase - - - 0.0 1136.0
HKD3_k127_3790530_10 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 558.0
HKD3_k127_3790530_11 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 523.0
HKD3_k127_3790530_12 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 500.0
HKD3_k127_3790530_13 4-hydroxybutyrate CoA-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 503.0
HKD3_k127_3790530_14 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 490.0
HKD3_k127_3790530_15 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 454.0
HKD3_k127_3790530_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 439.0
HKD3_k127_3790530_17 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 394.0
HKD3_k127_3790530_18 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 388.0
HKD3_k127_3790530_19 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 371.0
HKD3_k127_3790530_2 helicase superfamily c-terminal domain K03724 - - 0.0 1050.0
HKD3_k127_3790530_20 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 340.0
HKD3_k127_3790530_21 Type III secretion system lipoprotein chaperone (YscW) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 346.0
HKD3_k127_3790530_22 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 341.0
HKD3_k127_3790530_23 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
HKD3_k127_3790530_24 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 293.0
HKD3_k127_3790530_25 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002359 247.0
HKD3_k127_3790530_26 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000004236 251.0
HKD3_k127_3790530_27 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000001303 227.0
HKD3_k127_3790530_28 - - - - 0.000000000000000000000000000000000000000000000000000000005308 209.0
HKD3_k127_3790530_29 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000002094 200.0
HKD3_k127_3790530_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.14e-322 996.0
HKD3_k127_3790530_30 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000003539 194.0
HKD3_k127_3790530_31 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000001971 184.0
HKD3_k127_3790530_32 response regulator - - - 0.00000000000000000000000000000000000000000000006553 177.0
HKD3_k127_3790530_33 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000007245 184.0
HKD3_k127_3790530_34 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000000000008195 146.0
HKD3_k127_3790530_35 - - - - 0.0000000000000000000000000000003483 124.0
HKD3_k127_3790530_36 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000102 128.0
HKD3_k127_3790530_37 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000001253 131.0
HKD3_k127_3790530_38 Rhodanese Homology Domain - - - 0.00000000000000000000000000002171 126.0
HKD3_k127_3790530_39 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000367 124.0
HKD3_k127_3790530_4 Glucodextranase, domain N K01178 - 3.2.1.3 8.465e-317 992.0
HKD3_k127_3790530_40 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000003817 123.0
HKD3_k127_3790530_41 - - - - 0.00000000000000000003218 94.0
HKD3_k127_3790530_42 Copper binding periplasmic protein CusF - - - 0.000000000000000006264 91.0
HKD3_k127_3790530_43 - - - - 0.000000000000002899 82.0
HKD3_k127_3790530_44 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000351 83.0
HKD3_k127_3790530_45 - - - - 0.000000000009255 78.0
HKD3_k127_3790530_46 OST-HTH/LOTUS domain - - - 0.00000000005344 72.0
HKD3_k127_3790530_47 - - - - 0.00002095 57.0
HKD3_k127_3790530_5 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.715e-236 739.0
HKD3_k127_3790530_6 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 4.768e-224 707.0
HKD3_k127_3790530_7 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 2.733e-204 668.0
HKD3_k127_3790530_8 B12 binding domain - - - 3.368e-203 644.0
HKD3_k127_3790530_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 605.0
HKD3_k127_3798938_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 418.0
HKD3_k127_3798938_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 409.0
HKD3_k127_3798938_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 333.0
HKD3_k127_3798938_3 Psort location Extracellular, score K07126 - - 0.000000000000000000000000000000000000000000000000009251 188.0
HKD3_k127_3798938_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000001185 187.0
HKD3_k127_3798938_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000005156 171.0
HKD3_k127_3798938_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000008252 149.0
HKD3_k127_3798938_7 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000001444 153.0
HKD3_k127_3798938_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000002053 144.0
HKD3_k127_3798938_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000002689 98.0
HKD3_k127_3806498_0 Tricorn protease homolog K08676 - - 0.0 1137.0
HKD3_k127_3806498_1 oxidoreductase activity - - - 0.0 1084.0
HKD3_k127_3806498_10 AMP-binding enzyme C-terminal domain - - - 1.035e-194 620.0
HKD3_k127_3806498_11 ABC-type Fe3 transport system, periplasmic component - - - 8.667e-194 615.0
HKD3_k127_3806498_12 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 616.0
HKD3_k127_3806498_13 antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 590.0
HKD3_k127_3806498_14 Zinc-binding dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 553.0
HKD3_k127_3806498_15 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 524.0
HKD3_k127_3806498_16 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 496.0
HKD3_k127_3806498_17 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 471.0
HKD3_k127_3806498_18 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 452.0
HKD3_k127_3806498_19 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 422.0
HKD3_k127_3806498_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 6.714e-300 927.0
HKD3_k127_3806498_20 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 415.0
HKD3_k127_3806498_21 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 424.0
HKD3_k127_3806498_22 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 405.0
HKD3_k127_3806498_23 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 397.0
HKD3_k127_3806498_24 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 390.0
HKD3_k127_3806498_25 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
HKD3_k127_3806498_26 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 344.0
HKD3_k127_3806498_27 Nitrile hydratase K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 331.0
HKD3_k127_3806498_28 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 323.0
HKD3_k127_3806498_29 Threonyl alanyl tRNA synthetase K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
HKD3_k127_3806498_3 ABC-type Fe3 transport system permease component K02011 - - 8.821e-260 812.0
HKD3_k127_3806498_30 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 313.0
HKD3_k127_3806498_31 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 303.0
HKD3_k127_3806498_32 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 312.0
HKD3_k127_3806498_33 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 300.0
HKD3_k127_3806498_34 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 300.0
HKD3_k127_3806498_35 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006635 270.0
HKD3_k127_3806498_36 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000003384 255.0
HKD3_k127_3806498_37 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000006389 232.0
HKD3_k127_3806498_38 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000001683 237.0
HKD3_k127_3806498_39 Glyoxalase bleomycin resistance - - - 0.00000000000000000000000000000000000000000000000000000954 192.0
HKD3_k127_3806498_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.15e-233 733.0
HKD3_k127_3806498_40 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000325 198.0
HKD3_k127_3806498_41 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000005414 198.0
HKD3_k127_3806498_42 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000009195 154.0
HKD3_k127_3806498_43 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000001789 155.0
HKD3_k127_3806498_44 CHRD domain - - - 0.0000000000000000000000000000000001877 140.0
HKD3_k127_3806498_45 acyl-coA-binding protein - - - 0.000000000000000000000000000004459 136.0
HKD3_k127_3806498_46 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000005334 132.0
HKD3_k127_3806498_47 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000001388 105.0
HKD3_k127_3806498_48 cytochrome K17230 - - 0.000000000000000001186 99.0
HKD3_k127_3806498_49 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000002454 78.0
HKD3_k127_3806498_5 Periplasmic binding protein domain K01999 - - 7.582e-214 669.0
HKD3_k127_3806498_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 5.041e-213 679.0
HKD3_k127_3806498_7 Branched-chain amino acid transport system / permease component K01997,K01998 - - 3.363e-211 674.0
HKD3_k127_3806498_8 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 1.264e-205 645.0
HKD3_k127_3806498_9 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 2.098e-200 633.0
HKD3_k127_3810125_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000001495 196.0
HKD3_k127_3810125_1 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000000000000000000000000000000000004129 185.0
HKD3_k127_3810125_2 Periplasmic or secreted lipoprotein - - - 0.0000000000003249 81.0
HKD3_k127_3816282_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 8.041e-296 921.0
HKD3_k127_3816282_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.877e-213 675.0
HKD3_k127_3816282_2 coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 380.0
HKD3_k127_3816282_3 Putative aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 366.0
HKD3_k127_3816282_4 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000001076 155.0
HKD3_k127_3816282_5 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000003806 91.0
HKD3_k127_3842292_0 oxidoreductase K04090 - 1.2.7.8 0.0 1590.0
HKD3_k127_3842292_1 COG0457 FOG TPR repeat - - - 1.979e-235 747.0
HKD3_k127_3842292_10 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 424.0
HKD3_k127_3842292_11 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 400.0
HKD3_k127_3842292_12 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 355.0
HKD3_k127_3842292_13 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 335.0
HKD3_k127_3842292_14 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
HKD3_k127_3842292_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 317.0
HKD3_k127_3842292_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002401 270.0
HKD3_k127_3842292_17 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000003341 220.0
HKD3_k127_3842292_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000003877 242.0
HKD3_k127_3842292_19 membrane - - - 0.000000000000000000000000000000000000000000000000001356 186.0
HKD3_k127_3842292_2 type II secretion system protein E K02454 - - 3.912e-209 659.0
HKD3_k127_3842292_20 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000001138 190.0
HKD3_k127_3842292_21 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000000001763 188.0
HKD3_k127_3842292_22 general secretion pathway protein K02463 - - 0.000000000000000000000000000000000000000008363 163.0
HKD3_k127_3842292_23 - - - - 0.0000000000000000000000000000003534 126.0
HKD3_k127_3842292_24 General secretion pathway protein L K02461 - - 0.000000000000000000000000004178 128.0
HKD3_k127_3842292_25 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000007009 98.0
HKD3_k127_3842292_26 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000001209 96.0
HKD3_k127_3842292_27 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000787 85.0
HKD3_k127_3842292_28 general secretion pathway protein K02457 - - 0.000000000000000001619 98.0
HKD3_k127_3842292_29 general secretion pathway protein K02459 - - 0.000000000000000003173 96.0
HKD3_k127_3842292_3 general secretion pathway protein D K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 621.0
HKD3_k127_3842292_30 General secretion pathway K02462 - - 0.000000000007006 79.0
HKD3_k127_3842292_33 - K02452 - - 0.0001563 52.0
HKD3_k127_3842292_4 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 584.0
HKD3_k127_3842292_5 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 493.0
HKD3_k127_3842292_6 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 482.0
HKD3_k127_3842292_7 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 468.0
HKD3_k127_3842292_8 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 450.0
HKD3_k127_3842292_9 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 432.0
HKD3_k127_3858207_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.38e-220 690.0
HKD3_k127_3858207_1 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 507.0
HKD3_k127_3858207_2 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 438.0
HKD3_k127_3858207_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 336.0
HKD3_k127_3858207_4 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 339.0
HKD3_k127_3858207_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000006912 78.0
HKD3_k127_3858207_6 - - - - 0.0000259 51.0
HKD3_k127_3916658_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000002046 163.0
HKD3_k127_3916658_1 - - - - 0.00000000000009223 78.0
HKD3_k127_3961607_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1317.0
HKD3_k127_3961607_1 acyl-CoA dehydrogenase K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 571.0
HKD3_k127_3961607_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 484.0
HKD3_k127_3961607_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 464.0
HKD3_k127_3961607_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 436.0
HKD3_k127_3961607_5 ATPase activity, coupled to transmembrane movement of substances - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 403.0
HKD3_k127_3961607_6 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 364.0
HKD3_k127_3961607_7 Cytochrome c K08738 - - 0.000000000000000000000000000000004671 132.0
HKD3_k127_3961607_8 - - - - 0.0007807 45.0
HKD3_k127_4006856_0 TonB dependent receptor - - - 7.362e-299 953.0
HKD3_k127_4006856_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 354.0
HKD3_k127_4006856_2 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000007039 207.0
HKD3_k127_4006856_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000001173 196.0
HKD3_k127_4006856_4 Protein of unknown function (DUF3313) - - - 0.0000000000000001451 88.0
HKD3_k127_4006856_5 - - - - 0.0000000000335 73.0
HKD3_k127_4037534_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.916e-282 874.0
HKD3_k127_4037534_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 7.064e-281 885.0
HKD3_k127_4037534_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 381.0
HKD3_k127_4037534_11 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 330.0
HKD3_k127_4037534_12 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
HKD3_k127_4037534_13 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006414 248.0
HKD3_k127_4037534_14 PFAM Ig domain protein, group 1 domain protein K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000001064 259.0
HKD3_k127_4037534_15 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000001851 234.0
HKD3_k127_4037534_16 PFAM cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000007422 231.0
HKD3_k127_4037534_17 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000001437 205.0
HKD3_k127_4037534_18 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000001793 186.0
HKD3_k127_4037534_19 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000002617 194.0
HKD3_k127_4037534_2 Secretin and TonB N terminus short domain K02666 - - 2.625e-230 734.0
HKD3_k127_4037534_20 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000009725 184.0
HKD3_k127_4037534_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000002911 184.0
HKD3_k127_4037534_22 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000005279 153.0
HKD3_k127_4037534_23 Redoxin domain protein - - - 0.00000000000000000000000000000000000007938 150.0
HKD3_k127_4037534_24 Kelch motif - - - 0.0000000000000000000000000000000000002701 161.0
HKD3_k127_4037534_25 Transcriptional regulator - - - 0.0000000000000000000000000000000000003137 152.0
HKD3_k127_4037534_26 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000007913 140.0
HKD3_k127_4037534_27 PFAM RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000005938 137.0
HKD3_k127_4037534_28 Belongs to the frataxin family K06202 - - 0.000000000000000000000000000002564 127.0
HKD3_k127_4037534_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 539.0
HKD3_k127_4037534_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 536.0
HKD3_k127_4037534_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 530.0
HKD3_k127_4037534_6 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 512.0
HKD3_k127_4037534_7 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 453.0
HKD3_k127_4037534_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 435.0
HKD3_k127_4037534_9 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 416.0
HKD3_k127_414351_0 ribonuclease, Rne Rng family K08301 - - 2.937e-226 710.0
HKD3_k127_414351_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 557.0
HKD3_k127_414351_10 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000118 199.0
HKD3_k127_414351_11 PFAM O-Antigen - - - 0.0000000000000000000000000000000000000000000000000004042 204.0
HKD3_k127_414351_12 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000002081 183.0
HKD3_k127_414351_13 - - - - 0.00000000000000000000000000000000000000000000001592 183.0
HKD3_k127_414351_14 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000009671 168.0
HKD3_k127_414351_16 - - - - 0.00000000000000000002003 100.0
HKD3_k127_414351_17 - - - - 0.0000000000000000001074 96.0
HKD3_k127_414351_18 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000184 103.0
HKD3_k127_414351_19 heptosyltransferase K02843 - - 0.0000000000000000004699 91.0
HKD3_k127_414351_2 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 351.0
HKD3_k127_414351_20 - - - - 0.00000000000000006511 84.0
HKD3_k127_414351_21 Transglycosylase associated protein - - - 0.0000000000000309 81.0
HKD3_k127_414351_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 318.0
HKD3_k127_414351_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 293.0
HKD3_k127_414351_5 PFAM glycosyl transferase family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008545 292.0
HKD3_k127_414351_6 heptosyltransferase K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005304 265.0
HKD3_k127_414351_7 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000004815 254.0
HKD3_k127_414351_8 PFAM Glycosyl transferase, family 25 K07270 - - 0.00000000000000000000000000000000000000000000000000000000000000000249 245.0
HKD3_k127_414351_9 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000003521 216.0
HKD3_k127_4168131_0 Secretin and TonB N terminus short domain K02666 - - 1.178e-205 653.0
HKD3_k127_4205121_0 Sulfatase - - - 1.198e-261 824.0
HKD3_k127_4205121_1 Mandelate Racemase Muconate Lactonizing K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 520.0
HKD3_k127_4205121_10 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001533 240.0
HKD3_k127_4205121_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000006927 200.0
HKD3_k127_4205121_12 COG1226 Kef-type K transport systems - - - 0.000000000000000000000000000000000000000000000000000003321 198.0
HKD3_k127_4205121_13 - - - - 0.00000000000000000000000000000000000000000000000005006 181.0
HKD3_k127_4205121_14 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000892 156.0
HKD3_k127_4205121_15 Cysteine-rich CWC - - - 0.0000008651 59.0
HKD3_k127_4205121_2 aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 492.0
HKD3_k127_4205121_3 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 465.0
HKD3_k127_4205121_4 Amp-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 468.0
HKD3_k127_4205121_5 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 412.0
HKD3_k127_4205121_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 406.0
HKD3_k127_4205121_7 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 348.0
HKD3_k127_4205121_8 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 315.0
HKD3_k127_4205121_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 312.0
HKD3_k127_4229908_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 8.449e-277 862.0
HKD3_k127_4229908_1 phenylacetic acid degradation protein paaN - - - 2.979e-258 807.0
HKD3_k127_4229908_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 559.0
HKD3_k127_4229908_11 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 525.0
HKD3_k127_4229908_12 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 530.0
HKD3_k127_4229908_13 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 526.0
HKD3_k127_4229908_14 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 493.0
HKD3_k127_4229908_15 Ferritin-like K20087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 504.0
HKD3_k127_4229908_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 474.0
HKD3_k127_4229908_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 476.0
HKD3_k127_4229908_18 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 454.0
HKD3_k127_4229908_19 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 377.0
HKD3_k127_4229908_2 FAD binding domain K05712 - 1.14.13.127 7.176e-250 781.0
HKD3_k127_4229908_20 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 371.0
HKD3_k127_4229908_21 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 359.0
HKD3_k127_4229908_22 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 359.0
HKD3_k127_4229908_23 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 337.0
HKD3_k127_4229908_24 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 312.0
HKD3_k127_4229908_25 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
HKD3_k127_4229908_26 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004901 295.0
HKD3_k127_4229908_27 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005846 284.0
HKD3_k127_4229908_28 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003126 276.0
HKD3_k127_4229908_29 Histidine kinase K05962 - 2.7.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000219 259.0
HKD3_k127_4229908_3 Transcriptional regulator K00375 - - 9.873e-219 691.0
HKD3_k127_4229908_30 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009657 227.0
HKD3_k127_4229908_31 Pfam:DUF59 K02612 - - 0.00000000000000000000000000000000000000000000000000000000000001186 218.0
HKD3_k127_4229908_32 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000004566 209.0
HKD3_k127_4229908_33 phenylacetic acid degradation protein K02614 - - 0.00000000000000000000000000000000000000000000000001931 183.0
HKD3_k127_4229908_34 response regulator K07662 - - 0.000000000000000000000000000000000000000000000001399 178.0
HKD3_k127_4229908_35 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.000000000000000000000000000000000000000000000005403 177.0
HKD3_k127_4229908_36 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000001172 172.0
HKD3_k127_4229908_37 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000003898 154.0
HKD3_k127_4229908_38 Belongs to the peptidase S1B family K01318,K04775 - 3.4.21.19 0.0000000000000000000000000000000001796 147.0
HKD3_k127_4229908_39 Lecithin retinol acyltransferase - - - 0.00000000000000000000000000000001098 134.0
HKD3_k127_4229908_4 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 3.109e-215 678.0
HKD3_k127_4229908_40 - - - - 0.0000000000000000000000000001985 123.0
HKD3_k127_4229908_41 Protein of unknown function (DUF2783) - - - 0.000000000000000000000000004256 118.0
HKD3_k127_4229908_42 bacterial OsmY and nodulation domain - - - 0.00000000000000000000004105 103.0
HKD3_k127_4229908_43 - - - - 0.0000000000000000000001724 103.0
HKD3_k127_4229908_44 cheY-homologous receiver domain - - - 0.0000000000000000000006318 100.0
HKD3_k127_4229908_45 Cytochrome P460 - - - 0.0000000000000000243 91.0
HKD3_k127_4229908_46 Protein of unknown function (DUF1328) - - - 0.0000000000000002588 81.0
HKD3_k127_4229908_47 Heavy-metal resistance - - - 0.0000000000000003061 91.0
HKD3_k127_4229908_48 Glycine zipper K04062 - - 0.0000000000002026 73.0
HKD3_k127_4229908_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.225e-207 659.0
HKD3_k127_4229908_50 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000643 74.0
HKD3_k127_4229908_51 LTXXQ motif family protein - - - 0.000000000009587 73.0
HKD3_k127_4229908_53 EF hand - - - 0.0002564 48.0
HKD3_k127_4229908_6 Sodium/hydrogen exchanger family - - - 3.104e-197 623.0
HKD3_k127_4229908_7 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 599.0
HKD3_k127_4229908_8 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 586.0
HKD3_k127_4229908_9 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 578.0
HKD3_k127_4264503_0 response regulator K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 389.0
HKD3_k127_4264503_1 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 394.0
HKD3_k127_4264503_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000002051 203.0
HKD3_k127_4264503_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000002191 209.0
HKD3_k127_4264503_4 DNA integration - - - 0.0000003431 52.0
HKD3_k127_431358_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 617.0
HKD3_k127_431358_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 336.0
HKD3_k127_431358_2 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007507 265.0
HKD3_k127_431358_3 Benzoate-CoA ligase family K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000112 242.0
HKD3_k127_4393635_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08356 - 1.20.2.1,1.20.9.1 0.0 1048.0
HKD3_k127_4393635_1 arsenite oxidase, small subunit K08355 - 1.20.2.1,1.20.9.1 0.00000000001648 64.0
HKD3_k127_4462648_0 DNA helicase K03657 - 3.6.4.12 5.236e-317 994.0
HKD3_k127_4462648_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.876e-207 656.0
HKD3_k127_4462648_2 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 6.771e-199 628.0
HKD3_k127_4462648_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 374.0
HKD3_k127_4462648_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 321.0
HKD3_k127_4462648_5 - - - - 0.0000000000000000000000000000002342 132.0
HKD3_k127_457390_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 599.0
HKD3_k127_457390_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 354.0
HKD3_k127_457390_2 LysM domain K08086 - - 0.000000000000000000000000000000000000000006778 162.0
HKD3_k127_4631270_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1051.0
HKD3_k127_4631270_1 Fumarase C C-terminus K01744 - 4.3.1.1 3.82e-267 826.0
HKD3_k127_4631270_10 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000000000002013 148.0
HKD3_k127_4631270_11 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000009939 149.0
HKD3_k127_4631270_12 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000000002034 147.0
HKD3_k127_4631270_13 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.000000000000000000000000000000003882 129.0
HKD3_k127_4631270_2 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 3.085e-238 742.0
HKD3_k127_4631270_3 Sodium:dicarboxylate symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 538.0
HKD3_k127_4631270_4 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 479.0
HKD3_k127_4631270_5 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 396.0
HKD3_k127_4631270_6 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 294.0
HKD3_k127_4631270_7 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002941 276.0
HKD3_k127_4631270_8 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000001273 214.0
HKD3_k127_4631270_9 Gram-negative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002387 184.0
HKD3_k127_4682827_0 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 415.0
HKD3_k127_4682827_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005532 241.0
HKD3_k127_4682827_2 helix_turn_helix, Lux Regulon - - - 0.000228 46.0
HKD3_k127_468601_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
HKD3_k127_468601_1 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000001634 252.0
HKD3_k127_468601_2 - - - - 0.0000000000000000000000000000369 132.0
HKD3_k127_468601_3 - - - - 0.000000001813 69.0
HKD3_k127_4711888_0 SNARE associated Golgi protein - - - 5.345e-319 992.0
HKD3_k127_4711888_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.888e-271 838.0
HKD3_k127_4711888_10 cystathionine K01758 - 4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 462.0
HKD3_k127_4711888_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 425.0
HKD3_k127_4711888_12 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 381.0
HKD3_k127_4711888_13 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 334.0
HKD3_k127_4711888_14 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001219 287.0
HKD3_k127_4711888_15 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005894 261.0
HKD3_k127_4711888_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
HKD3_k127_4711888_17 PFAM PilT protein domain protein - - - 0.00000000000000000000000000000000000000000000000002786 182.0
HKD3_k127_4711888_18 COG0466 ATP-dependent Lon protease, bacterial type - - - 0.00000000000000000000000000000000000000000000000006242 182.0
HKD3_k127_4711888_19 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000002479 169.0
HKD3_k127_4711888_2 Tripartite tricarboxylate transporter TctA family - - - 2.356e-239 748.0
HKD3_k127_4711888_20 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000003542 142.0
HKD3_k127_4711888_21 prlF antitoxin for toxin YhaV_toxin - - - 0.000000000000000000000000006411 113.0
HKD3_k127_4711888_22 FixH family K09926 - - 0.000000000000000000000001711 109.0
HKD3_k127_4711888_23 - - - - 0.000000000000000000004852 97.0
HKD3_k127_4711888_24 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000001955 86.0
HKD3_k127_4711888_25 Cbb3-type cytochrome oxidase K00407 - - 0.00000000000001024 74.0
HKD3_k127_4711888_26 Transmembrane anti-sigma factor - - - 0.00000005856 57.0
HKD3_k127_4711888_27 - - - - 0.00000007762 64.0
HKD3_k127_4711888_28 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000006058 51.0
HKD3_k127_4711888_29 Bacterial regulatory proteins, crp family K01420 - - 0.0001315 44.0
HKD3_k127_4711888_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.38e-230 728.0
HKD3_k127_4711888_4 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 577.0
HKD3_k127_4711888_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 578.0
HKD3_k127_4711888_6 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 534.0
HKD3_k127_4711888_7 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 462.0
HKD3_k127_4711888_8 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 462.0
HKD3_k127_4711888_9 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 457.0
HKD3_k127_4773369_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 469.0
HKD3_k127_4773369_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 413.0
HKD3_k127_4773369_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002604 256.0
HKD3_k127_4773369_11 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001559 252.0
HKD3_k127_4773369_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009458 254.0
HKD3_k127_4773369_13 Transcriptional regulator K21747 - - 0.000000000000000000000000000000000000000000000000000000000000000000005585 247.0
HKD3_k127_4773369_14 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000007506 227.0
HKD3_k127_4773369_15 AMP-binding enzyme - - - 0.000000000000000000000000000000000001179 143.0
HKD3_k127_4773369_16 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000006469 135.0
HKD3_k127_4773369_17 - - - - 0.00000000000000000000000000000003567 132.0
HKD3_k127_4773369_18 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000004251 121.0
HKD3_k127_4773369_19 enzyme related to lactoylglutathione lyase K06996 - - 0.000000000000000000000009336 106.0
HKD3_k127_4773369_2 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 419.0
HKD3_k127_4773369_3 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 369.0
HKD3_k127_4773369_4 Domain of unknown function (DUF4357) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
HKD3_k127_4773369_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 341.0
HKD3_k127_4773369_6 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 333.0
HKD3_k127_4773369_7 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 304.0
HKD3_k127_4773369_8 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001573 281.0
HKD3_k127_4773369_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000001236 266.0
HKD3_k127_4844627_0 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000006732 80.0
HKD3_k127_4844627_1 MASE1 K07709 - 2.7.13.3 0.0000000000006482 80.0
HKD3_k127_4849093_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1345.0
HKD3_k127_4849093_1 DNA polymerase K02337 - 2.7.7.7 0.0 1111.0
HKD3_k127_4849093_10 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 500.0
HKD3_k127_4849093_11 Lytic transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 446.0
HKD3_k127_4849093_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 430.0
HKD3_k127_4849093_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 347.0
HKD3_k127_4849093_14 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 340.0
HKD3_k127_4849093_15 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
HKD3_k127_4849093_16 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
HKD3_k127_4849093_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 320.0
HKD3_k127_4849093_18 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 304.0
HKD3_k127_4849093_19 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 300.0
HKD3_k127_4849093_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.393e-294 927.0
HKD3_k127_4849093_20 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004703 286.0
HKD3_k127_4849093_21 HlyD family secretion protein K13408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000781 274.0
HKD3_k127_4849093_22 Glycosyltransferase family 9 (heptosyltransferase) K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002387 276.0
HKD3_k127_4849093_23 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001234 233.0
HKD3_k127_4849093_24 PFAM Glycosyl transferase, family 25 K07270 - - 0.0000000000000000000000000000000000000000000000000000000000000000572 230.0
HKD3_k127_4849093_25 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000008822 228.0
HKD3_k127_4849093_26 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000002035 222.0
HKD3_k127_4849093_27 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000003444 227.0
HKD3_k127_4849093_28 heptosyltransferase K02843 - - 0.00000000000000000000000000000000000000000000000000000002968 214.0
HKD3_k127_4849093_29 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000009066 207.0
HKD3_k127_4849093_3 ribonuclease, Rne Rng family K08301 - - 3.479e-217 694.0
HKD3_k127_4849093_30 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000003492 184.0
HKD3_k127_4849093_31 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000001239 179.0
HKD3_k127_4849093_32 PFAM O-Antigen - - - 0.00000000000000000000000000000000000000000000002029 193.0
HKD3_k127_4849093_33 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000004474 158.0
HKD3_k127_4849093_34 pilus organization K07346 - - 0.00000000000000000000000000000000000003987 153.0
HKD3_k127_4849093_35 - - - - 0.000000003735 58.0
HKD3_k127_4849093_36 - - - - 0.0000001181 54.0
HKD3_k127_4849093_4 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 3.225e-204 680.0
HKD3_k127_4849093_5 Peptidase C39 family K13409 - - 3.552e-202 651.0
HKD3_k127_4849093_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 602.0
HKD3_k127_4849093_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 515.0
HKD3_k127_4849093_8 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 510.0
HKD3_k127_4849093_9 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 524.0
HKD3_k127_48885_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 3.295e-315 984.0
HKD3_k127_48885_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 543.0
HKD3_k127_48885_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 302.0
HKD3_k127_48885_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 288.0
HKD3_k127_48885_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001904 241.0
HKD3_k127_48885_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000009426 226.0
HKD3_k127_48885_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000004212 156.0
HKD3_k127_4910763_0 FAD linked oxidase domain protein - - - 0.0 1945.0
HKD3_k127_4910763_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.669e-279 869.0
HKD3_k127_4910763_10 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 568.0
HKD3_k127_4910763_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 563.0
HKD3_k127_4910763_12 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 538.0
HKD3_k127_4910763_13 Soluble lytic murein K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 547.0
HKD3_k127_4910763_14 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 532.0
HKD3_k127_4910763_15 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 530.0
HKD3_k127_4910763_16 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 528.0
HKD3_k127_4910763_17 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 521.0
HKD3_k127_4910763_18 Cobalamin biosynthesis protein CobW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 505.0
HKD3_k127_4910763_19 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 503.0
HKD3_k127_4910763_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.398e-267 829.0
HKD3_k127_4910763_20 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 471.0
HKD3_k127_4910763_21 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 480.0
HKD3_k127_4910763_22 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 468.0
HKD3_k127_4910763_23 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 463.0
HKD3_k127_4910763_24 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 456.0
HKD3_k127_4910763_25 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 456.0
HKD3_k127_4910763_26 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 406.0
HKD3_k127_4910763_27 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 394.0
HKD3_k127_4910763_28 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 378.0
HKD3_k127_4910763_29 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 390.0
HKD3_k127_4910763_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 2.077e-247 773.0
HKD3_k127_4910763_30 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 398.0
HKD3_k127_4910763_31 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 358.0
HKD3_k127_4910763_32 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 349.0
HKD3_k127_4910763_33 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 345.0
HKD3_k127_4910763_34 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 332.0
HKD3_k127_4910763_35 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
HKD3_k127_4910763_36 Nad-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 317.0
HKD3_k127_4910763_37 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 301.0
HKD3_k127_4910763_38 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 319.0
HKD3_k127_4910763_39 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001443 310.0
HKD3_k127_4910763_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.623e-235 730.0
HKD3_k127_4910763_40 acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
HKD3_k127_4910763_41 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 276.0
HKD3_k127_4910763_42 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001037 276.0
HKD3_k127_4910763_43 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
HKD3_k127_4910763_44 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
HKD3_k127_4910763_45 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004498 266.0
HKD3_k127_4910763_46 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000008339 271.0
HKD3_k127_4910763_47 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000009746 272.0
HKD3_k127_4910763_48 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001079 272.0
HKD3_k127_4910763_49 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000309 247.0
HKD3_k127_4910763_5 DNA polymerase X family K02347 - - 2.792e-212 674.0
HKD3_k127_4910763_50 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
HKD3_k127_4910763_51 Alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000001537 239.0
HKD3_k127_4910763_52 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
HKD3_k127_4910763_53 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
HKD3_k127_4910763_54 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000008937 233.0
HKD3_k127_4910763_55 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000001262 220.0
HKD3_k127_4910763_56 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000147 233.0
HKD3_k127_4910763_57 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000002146 216.0
HKD3_k127_4910763_58 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000003232 228.0
HKD3_k127_4910763_59 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000006115 228.0
HKD3_k127_4910763_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.884e-210 660.0
HKD3_k127_4910763_60 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000001324 208.0
HKD3_k127_4910763_61 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000001172 213.0
HKD3_k127_4910763_62 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000005008 198.0
HKD3_k127_4910763_63 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000008693 196.0
HKD3_k127_4910763_64 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000002533 199.0
HKD3_k127_4910763_65 Lysin motif - - - 0.0000000000000000000000000000000000000000000000008521 180.0
HKD3_k127_4910763_66 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000004662 181.0
HKD3_k127_4910763_67 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000873 173.0
HKD3_k127_4910763_68 Ferredoxin - - - 0.000000000000000000000000000000000000000000001405 171.0
HKD3_k127_4910763_69 DNA polymerase III, epsilon K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000005484 188.0
HKD3_k127_4910763_7 Psort location CytoplasmicMembrane, score K07793 - - 1.551e-207 656.0
HKD3_k127_4910763_70 Histidine triad (HIT) - - - 0.00000000000000000000000000000000000000000008231 166.0
HKD3_k127_4910763_71 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000201 165.0
HKD3_k127_4910763_72 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000002808 168.0
HKD3_k127_4910763_73 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000001732 154.0
HKD3_k127_4910763_74 PFAM transport-associated - - - 0.0000000000000000000000000000000000001747 154.0
HKD3_k127_4910763_75 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000009226 143.0
HKD3_k127_4910763_76 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000001642 140.0
HKD3_k127_4910763_77 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000001227 137.0
HKD3_k127_4910763_78 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001481 125.0
HKD3_k127_4910763_79 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000004466 126.0
HKD3_k127_4910763_8 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 614.0
HKD3_k127_4910763_80 membrane K08972 - - 0.000000000000000000000000000004022 134.0
HKD3_k127_4910763_81 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000002334 124.0
HKD3_k127_4910763_82 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000008244 121.0
HKD3_k127_4910763_83 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000002746 115.0
HKD3_k127_4910763_84 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000004831 112.0
HKD3_k127_4910763_85 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000008748 112.0
HKD3_k127_4910763_86 PFAM Sporulation domain protein - - - 0.00000000000000000000004761 107.0
HKD3_k127_4910763_87 Integral membrane protein (DUF2244) - - - 0.00000000000000000006866 98.0
HKD3_k127_4910763_88 Protein of unknown function (DUF2905) - - - 0.0000000000000000004721 87.0
HKD3_k127_4910763_89 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000001079 76.0
HKD3_k127_4910763_9 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 605.0
HKD3_k127_4910763_90 - - - - 0.0000000000003178 82.0
HKD3_k127_4910763_91 PFAM Phosphoribosyltransferase - - - 0.000000000003967 73.0
HKD3_k127_4910763_92 Tripartite tricarboxylate transporter TctB family - - - 0.0000001445 61.0
HKD3_k127_4910763_94 Copper-exporting ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0001843 46.0
HKD3_k127_4917153_0 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 479.0
HKD3_k127_4917153_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000003835 136.0
HKD3_k127_4917153_2 PFAM Lytic transglycosylase catalytic - - - 0.0008684 44.0
HKD3_k127_4918008_0 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 424.0
HKD3_k127_4918008_1 Transmembrane secretion effector - - - 0.000000001154 62.0
HKD3_k127_4928883_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1289.0
HKD3_k127_4928883_1 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1191.0
HKD3_k127_4928883_10 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
HKD3_k127_4928883_11 LysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 466.0
HKD3_k127_4928883_12 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 458.0
HKD3_k127_4928883_13 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 450.0
HKD3_k127_4928883_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 428.0
HKD3_k127_4928883_15 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 424.0
HKD3_k127_4928883_16 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 427.0
HKD3_k127_4928883_17 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 428.0
HKD3_k127_4928883_18 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 418.0
HKD3_k127_4928883_19 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 391.0
HKD3_k127_4928883_2 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 2.518e-287 889.0
HKD3_k127_4928883_20 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 336.0
HKD3_k127_4928883_21 Short-chain dehydrogenase reductase sdr K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 350.0
HKD3_k127_4928883_22 ATP-grasp domain K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007028 282.0
HKD3_k127_4928883_23 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001917 280.0
HKD3_k127_4928883_24 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
HKD3_k127_4928883_25 PFAM regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000202 248.0
HKD3_k127_4928883_26 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000001561 241.0
HKD3_k127_4928883_27 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000001717 220.0
HKD3_k127_4928883_28 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
HKD3_k127_4928883_29 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000008605 210.0
HKD3_k127_4928883_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 9.921e-240 761.0
HKD3_k127_4928883_30 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000000000003352 219.0
HKD3_k127_4928883_31 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000000000005427 186.0
HKD3_k127_4928883_32 endoribonuclease K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000009769 171.0
HKD3_k127_4928883_33 RES - - - 0.000000000000000000000000000000000000000000004334 171.0
HKD3_k127_4928883_34 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000000001492 145.0
HKD3_k127_4928883_35 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000006005 144.0
HKD3_k127_4928883_37 - - - - 0.00000000000000000002323 97.0
HKD3_k127_4928883_38 Aspartyl protease K06985 - - 0.0000000000000001407 91.0
HKD3_k127_4928883_39 Type II/IV secretion system protein K02670 - - 0.00000000000006255 74.0
HKD3_k127_4928883_4 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.35e-218 698.0
HKD3_k127_4928883_40 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000001523 61.0
HKD3_k127_4928883_41 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00002735 50.0
HKD3_k127_4928883_5 Periplasmic binding protein K01999 - - 3.315e-208 655.0
HKD3_k127_4928883_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 9.897e-199 625.0
HKD3_k127_4928883_7 Pilus retraction K02669,K12203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 578.0
HKD3_k127_4928883_8 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 537.0
HKD3_k127_4928883_9 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 537.0
HKD3_k127_4938795_0 malic enzyme K00029 - 1.1.1.40 4.117e-213 670.0
HKD3_k127_4938795_1 PFAM aminotransferase class I and II - - - 0.00000000000000000003989 93.0
HKD3_k127_4942831_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 379.0
HKD3_k127_4942831_1 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000002049 201.0
HKD3_k127_4945020_0 Sulfatase K01130 - 3.1.6.1 0.0 1498.0
HKD3_k127_4945020_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1485.0
HKD3_k127_4945020_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 376.0
HKD3_k127_4945020_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 370.0
HKD3_k127_4945020_12 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 370.0
HKD3_k127_4945020_13 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 312.0
HKD3_k127_4945020_14 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 299.0
HKD3_k127_4945020_15 NhaP-type Na H and K H antiporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006377 270.0
HKD3_k127_4945020_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 257.0
HKD3_k127_4945020_17 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005016 248.0
HKD3_k127_4945020_18 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000004269 204.0
HKD3_k127_4945020_19 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000000000000006413 198.0
HKD3_k127_4945020_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 - 3.6.3.25 7.112e-292 902.0
HKD3_k127_4945020_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000007181 182.0
HKD3_k127_4945020_21 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000001278 173.0
HKD3_k127_4945020_22 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000000000000000000006623 130.0
HKD3_k127_4945020_23 - - - - 0.00000000000000000000000000000009136 132.0
HKD3_k127_4945020_24 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000000000000000009128 126.0
HKD3_k127_4945020_25 - - - - 0.000000000000000000000000000426 116.0
HKD3_k127_4945020_26 - - - - 0.000000000000000000000000002701 113.0
HKD3_k127_4945020_3 regulation of DNA-templated transcription, elongation - - - 4.964e-281 888.0
HKD3_k127_4945020_4 Protein of unknown function (DUF1214) - - - 1.603e-243 762.0
HKD3_k127_4945020_5 Patatin-like phospholipase K07001 - - 1.979e-239 772.0
HKD3_k127_4945020_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.056e-195 623.0
HKD3_k127_4945020_7 Protein of unknown function (DUF1538) - - - 5.841e-195 631.0
HKD3_k127_4945020_8 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 559.0
HKD3_k127_4945020_9 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 444.0
HKD3_k127_4952466_0 Domain of unknown function (DUF5117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 329.0
HKD3_k127_4952466_1 Ligated ion channel L-glutamate- and glycine-binding site K02030 - - 0.0000000000000000000000000000000000000000000000001608 188.0
HKD3_k127_4952466_10 plasmid stabilization protein K21495 - - 0.00000000000003831 81.0
HKD3_k127_4952466_11 Acetyltransferase (GNAT) domain - - - 0.000000000001784 69.0
HKD3_k127_4952466_12 Domain of unknown function (DUF1845) - - - 0.0000000001142 66.0
HKD3_k127_4952466_13 Protein of unknown function (DUF2384) - - - 0.00000002186 59.0
HKD3_k127_4952466_14 Protein of unknown function (DUF2384) - - - 0.0000003824 52.0
HKD3_k127_4952466_15 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000878 56.0
HKD3_k127_4952466_2 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000006359 174.0
HKD3_k127_4952466_3 RES - - - 0.00000000000000000000000000000000000001768 148.0
HKD3_k127_4952466_4 PIN domain K07062 - - 0.0000000000000000000000000000000000008891 148.0
HKD3_k127_4952466_5 - - - - 0.000000000000000000000003213 108.0
HKD3_k127_4952466_7 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000004475 100.0
HKD3_k127_4952466_8 Protein conserved in bacteria - - - 0.0000000000000000000002908 100.0
HKD3_k127_4952466_9 RES - - - 0.0000000000000009978 77.0
HKD3_k127_4972818_0 PrkA family serine protein kinase K07180 GO:0003674,GO:0003824,GO:0004672,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0042594,GO:0043170,GO:0043412,GO:0043562,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 7.324e-280 874.0
HKD3_k127_4972818_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.705e-253 799.0
HKD3_k127_4972818_10 cytochrome C oxidase K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001878 244.0
HKD3_k127_4972818_11 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000004999 215.0
HKD3_k127_4972818_12 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000004484 215.0
HKD3_k127_4972818_13 Protein of unknown function (DUF2970) - - - 0.0000000000000000001734 89.0
HKD3_k127_4972818_14 - - - - 0.00002196 55.0
HKD3_k127_4972818_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.137e-220 687.0
HKD3_k127_4972818_3 SpoVR family K06415 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 572.0
HKD3_k127_4972818_4 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 423.0
HKD3_k127_4972818_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 433.0
HKD3_k127_4972818_6 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 418.0
HKD3_k127_4972818_7 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 398.0
HKD3_k127_4972818_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 396.0
HKD3_k127_4972818_9 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001705 252.0
HKD3_k127_4974789_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1022.0
HKD3_k127_497877_0 Multicopper oxidase - - - 0.0 1038.0
HKD3_k127_497877_1 Prolyl oligopeptidase K01322 - 3.4.21.26 3.544e-244 773.0
HKD3_k127_497877_10 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 401.0
HKD3_k127_497877_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 402.0
HKD3_k127_497877_12 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 378.0
HKD3_k127_497877_13 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 372.0
HKD3_k127_497877_14 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 362.0
HKD3_k127_497877_15 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 295.0
HKD3_k127_497877_16 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001242 278.0
HKD3_k127_497877_17 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
HKD3_k127_497877_18 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
HKD3_k127_497877_19 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000005372 230.0
HKD3_k127_497877_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 5.137e-221 690.0
HKD3_k127_497877_20 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000001673 186.0
HKD3_k127_497877_21 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000008839 156.0
HKD3_k127_497877_22 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000003098 145.0
HKD3_k127_497877_24 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000001266 144.0
HKD3_k127_497877_25 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000006364 130.0
HKD3_k127_497877_26 - - - - 0.00000000000000000000000000000007329 129.0
HKD3_k127_497877_27 Rubrerythrin - - - 0.000000000000000000000000000001959 137.0
HKD3_k127_497877_28 GCN5-related N-acetyltransferase K09181 - - 0.000000000000000000000000000002908 130.0
HKD3_k127_497877_29 Cytochrome P460 - - - 0.00000000000000000000000004125 119.0
HKD3_k127_497877_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.305e-210 669.0
HKD3_k127_497877_30 cytochrome - - - 0.000000000000001021 87.0
HKD3_k127_497877_32 LTXXQ motif family protein - - - 0.0000000000001285 80.0
HKD3_k127_497877_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 3.725e-209 661.0
HKD3_k127_497877_5 Aminotransferase class-III K00823 - 2.6.1.19 3.667e-198 629.0
HKD3_k127_497877_6 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 563.0
HKD3_k127_497877_7 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 563.0
HKD3_k127_497877_8 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 457.0
HKD3_k127_497877_9 PFAM Rieske 2Fe-2S K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 428.0
HKD3_k127_499231_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1118.0
HKD3_k127_499231_1 Elongation factor G, domain IV K02355 - - 2.202e-311 966.0
HKD3_k127_499231_10 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000001306 210.0
HKD3_k127_499231_11 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000005801 201.0
HKD3_k127_499231_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000007731 202.0
HKD3_k127_499231_13 Belongs to the thioredoxin family K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000000003048 158.0
HKD3_k127_499231_2 Aldehyde dehydrogenase family - - - 2.213e-201 639.0
HKD3_k127_499231_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 581.0
HKD3_k127_499231_4 Acyl-CoA dehydrogenase, C-terminal domain K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 591.0
HKD3_k127_499231_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 393.0
HKD3_k127_499231_6 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 366.0
HKD3_k127_499231_7 Peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 334.0
HKD3_k127_499231_8 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 332.0
HKD3_k127_499231_9 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 308.0
HKD3_k127_4996122_0 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 576.0
HKD3_k127_4996122_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 546.0
HKD3_k127_4996122_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 520.0
HKD3_k127_4996122_3 THUMP domain K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 443.0
HKD3_k127_4996122_4 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 360.0
HKD3_k127_4996122_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000699 252.0
HKD3_k127_4996122_6 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000000001904 205.0
HKD3_k127_4996122_7 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000007781 175.0
HKD3_k127_4996122_8 twitching motility protein K02669,K12203 - - 0.0000000000000000000000000000000001096 136.0
HKD3_k127_4996122_9 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000008568 131.0
HKD3_k127_5001460_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.774e-255 797.0
HKD3_k127_5001460_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.27e-227 713.0
HKD3_k127_5001460_10 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 433.0
HKD3_k127_5001460_11 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 436.0
HKD3_k127_5001460_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 425.0
HKD3_k127_5001460_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
HKD3_k127_5001460_14 Membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 367.0
HKD3_k127_5001460_15 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 338.0
HKD3_k127_5001460_16 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 323.0
HKD3_k127_5001460_17 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 314.0
HKD3_k127_5001460_18 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 304.0
HKD3_k127_5001460_19 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 317.0
HKD3_k127_5001460_2 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 4.304e-215 681.0
HKD3_k127_5001460_20 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004807 275.0
HKD3_k127_5001460_21 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002187 278.0
HKD3_k127_5001460_22 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009974 273.0
HKD3_k127_5001460_23 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000376 274.0
HKD3_k127_5001460_24 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000001137 230.0
HKD3_k127_5001460_25 FMN_bind K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
HKD3_k127_5001460_26 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000002048 211.0
HKD3_k127_5001460_27 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000002006 208.0
HKD3_k127_5001460_28 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000001761 184.0
HKD3_k127_5001460_29 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000003412 176.0
HKD3_k127_5001460_3 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 588.0
HKD3_k127_5001460_30 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000002407 177.0
HKD3_k127_5001460_31 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000006964 160.0
HKD3_k127_5001460_32 PFAM Isochorismatase - - - 0.000000000000000000000000000000000002137 144.0
HKD3_k127_5001460_33 PFAM CBS domain containing protein - - - 0.000000000000000000000009775 106.0
HKD3_k127_5001460_35 Hydrogenase maturation protease - - - 0.0000000000002211 83.0
HKD3_k127_5001460_36 Acetyltransferase (GNAT) domain - - - 0.00000005372 65.0
HKD3_k127_5001460_39 - - - - 0.0000924 48.0
HKD3_k127_5001460_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 544.0
HKD3_k127_5001460_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 521.0
HKD3_k127_5001460_6 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 497.0
HKD3_k127_5001460_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 466.0
HKD3_k127_5001460_8 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 463.0
HKD3_k127_5001460_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 444.0
HKD3_k127_5044195_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 481.0
HKD3_k127_5044195_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 311.0
HKD3_k127_5061021_0 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000000002633 209.0
HKD3_k127_5061021_1 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000003722 187.0
HKD3_k127_5061021_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000001377 166.0
HKD3_k127_5081736_0 Diguanylate cyclase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 351.0
HKD3_k127_5081736_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000003642 230.0
HKD3_k127_5084538_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 389.0
HKD3_k127_5084538_1 pfam abc1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 377.0
HKD3_k127_5084538_10 - - - - 0.0000007946 59.0
HKD3_k127_5084538_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 362.0
HKD3_k127_5084538_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000002877 220.0
HKD3_k127_5084538_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000004561 219.0
HKD3_k127_5084538_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000002145 198.0
HKD3_k127_5084538_6 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000003278 147.0
HKD3_k127_5084538_7 Protein of unknown function (DUF433) - - - 0.000000000000000000000000002058 115.0
HKD3_k127_5084538_8 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000006445 104.0
HKD3_k127_5084538_9 COGs COG4634 conserved - - - 0.000000001185 64.0
HKD3_k127_5088321_0 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 336.0
HKD3_k127_5088321_1 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000797 122.0
HKD3_k127_5088321_2 Domain of unknown function (DUF4010) - - - 0.0000000000000000006188 91.0
HKD3_k127_5099370_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 559.0
HKD3_k127_5099370_1 PIN domain - - - 0.00000000000000000000000000001849 126.0
HKD3_k127_5099370_2 positive regulation of growth - - - 0.00000000000000005034 84.0
HKD3_k127_5099370_3 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000002675 49.0
HKD3_k127_5103273_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000004563 167.0
HKD3_k127_5122258_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 4.138e-218 687.0
HKD3_k127_5122258_1 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 289.0
HKD3_k127_5122258_2 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000001071 218.0
HKD3_k127_5122258_3 Actin K03569 - - 0.00000000000000000000000001484 108.0
HKD3_k127_5145507_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1227.0
HKD3_k127_5145507_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 2.066e-200 637.0
HKD3_k127_5145507_10 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 361.0
HKD3_k127_5145507_11 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
HKD3_k127_5145507_12 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 338.0
HKD3_k127_5145507_13 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 331.0
HKD3_k127_5145507_14 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 332.0
HKD3_k127_5145507_15 PFAM L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 333.0
HKD3_k127_5145507_16 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
HKD3_k127_5145507_17 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 303.0
HKD3_k127_5145507_18 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 314.0
HKD3_k127_5145507_19 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 294.0
HKD3_k127_5145507_2 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 526.0
HKD3_k127_5145507_20 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 295.0
HKD3_k127_5145507_21 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
HKD3_k127_5145507_22 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000004241 240.0
HKD3_k127_5145507_23 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
HKD3_k127_5145507_24 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000001109 230.0
HKD3_k127_5145507_25 lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000002347 233.0
HKD3_k127_5145507_26 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000001143 192.0
HKD3_k127_5145507_27 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000309 189.0
HKD3_k127_5145507_28 Protein of unknown function (DUF3833) - - - 0.000000000000000000000000000000000000000000000000004677 203.0
HKD3_k127_5145507_29 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000001007 182.0
HKD3_k127_5145507_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 515.0
HKD3_k127_5145507_30 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000006716 161.0
HKD3_k127_5145507_31 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000004455 144.0
HKD3_k127_5145507_32 - - - - 0.0000000000000000000000000003111 132.0
HKD3_k127_5145507_33 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000004173 128.0
HKD3_k127_5145507_34 - - - - 0.0000000000000000000000000894 116.0
HKD3_k127_5145507_35 FabA-like domain - - - 0.00000000000000000000000009816 119.0
HKD3_k127_5145507_36 Protein of unknown function (DUF3108) - - - 0.00000000000000001027 93.0
HKD3_k127_5145507_37 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.00000000000002644 76.0
HKD3_k127_5145507_38 Serine threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15502,K15504 - - 0.0000000000001499 84.0
HKD3_k127_5145507_39 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0004875 53.0
HKD3_k127_5145507_4 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 504.0
HKD3_k127_5145507_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 484.0
HKD3_k127_5145507_6 Formate dehydrogenase N, transmembrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 454.0
HKD3_k127_5145507_7 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 460.0
HKD3_k127_5145507_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 446.0
HKD3_k127_5145507_9 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 356.0
HKD3_k127_5158771_0 protein related to plant photosystem II stability assembly factor - - - 1.265e-205 646.0
HKD3_k127_5158771_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 616.0
HKD3_k127_5158771_10 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 416.0
HKD3_k127_5158771_11 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K03778 - 1.1.1.28,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 387.0
HKD3_k127_5158771_12 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 376.0
HKD3_k127_5158771_13 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 342.0
HKD3_k127_5158771_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 332.0
HKD3_k127_5158771_15 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 324.0
HKD3_k127_5158771_17 Baseplate J-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 304.0
HKD3_k127_5158771_18 Diguanylate cyclase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000002246 277.0
HKD3_k127_5158771_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 555.0
HKD3_k127_5158771_20 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000004556 242.0
HKD3_k127_5158771_21 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
HKD3_k127_5158771_22 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
HKD3_k127_5158771_24 self proteolysis K20276 - - 0.00000000000000000000000000000000000000000000000000000000002127 239.0
HKD3_k127_5158771_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000000000000022 211.0
HKD3_k127_5158771_26 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000003342 185.0
HKD3_k127_5158771_27 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000000008602 183.0
HKD3_k127_5158771_28 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001455 176.0
HKD3_k127_5158771_29 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000002106 176.0
HKD3_k127_5158771_3 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 541.0
HKD3_k127_5158771_31 YCII-related domain - - - 0.000000000000000000000000000000000000000007007 158.0
HKD3_k127_5158771_32 PAAR repeat-containing protein - - - 0.00000000000000000000000000000000000000004076 155.0
HKD3_k127_5158771_33 Rhs element vgr protein K11904 - - 0.00000000000000000000000000000000000017 156.0
HKD3_k127_5158771_34 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000008198 149.0
HKD3_k127_5158771_35 DNA circulation - - - 0.000000000000000000000000000000000001624 146.0
HKD3_k127_5158771_36 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000005319 140.0
HKD3_k127_5158771_37 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000001387 151.0
HKD3_k127_5158771_38 Late control gene D protein - - - 0.0000000000000000000000000000000000711 146.0
HKD3_k127_5158771_39 phosphorelay signal transduction system - - - 0.00000000000000000000000000001298 129.0
HKD3_k127_5158771_4 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 533.0
HKD3_k127_5158771_41 ThiS family K03636 - - 0.00000000000000000000000000007462 117.0
HKD3_k127_5158771_42 Dodecin K09165 - - 0.000000000000000000000002342 107.0
HKD3_k127_5158771_43 - - - - 0.00000000000000000005184 94.0
HKD3_k127_5158771_45 Phage protein GP46 - - - 0.0000000000000001512 86.0
HKD3_k127_5158771_46 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000004151 75.0
HKD3_k127_5158771_47 - - - - 0.00000000002441 73.0
HKD3_k127_5158771_48 nuclear chromosome segregation - - - 0.0000002042 64.0
HKD3_k127_5158771_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 546.0
HKD3_k127_5158771_50 WD40 repeats - - - 0.0003862 51.0
HKD3_k127_5158771_51 ATPases associated with a variety of cellular activities - - - 0.0008665 48.0
HKD3_k127_5158771_6 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 534.0
HKD3_k127_5158771_7 sulfate ABC transporter K02046,K15496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 447.0
HKD3_k127_5158771_8 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 460.0
HKD3_k127_5158771_9 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 411.0
HKD3_k127_5180287_0 protein involved in propionate catabolism K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 546.0
HKD3_k127_5180287_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 499.0
HKD3_k127_5180287_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000001555 175.0
HKD3_k127_5180287_11 atpase or kinase K06925 - - 0.0000000000000000000000000000000000007418 149.0
HKD3_k127_5180287_12 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006 - - 0.00000000002006 74.0
HKD3_k127_5180287_2 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 469.0
HKD3_k127_5180287_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 466.0
HKD3_k127_5180287_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 436.0
HKD3_k127_5180287_5 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 302.0
HKD3_k127_5180287_6 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000002276 241.0
HKD3_k127_5180287_7 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000003151 230.0
HKD3_k127_5180287_8 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000005027 184.0
HKD3_k127_5180287_9 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000319 182.0
HKD3_k127_5181640_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.565e-269 845.0
HKD3_k127_5181640_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 3.743e-237 736.0
HKD3_k127_5181640_10 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000002072 150.0
HKD3_k127_5181640_11 - - - - 0.00000000000000000000000000000001965 128.0
HKD3_k127_5181640_12 cell division protein - - - 0.0000000000000000000000000003534 123.0
HKD3_k127_5181640_13 membrane - - - 0.00000000000001648 81.0
HKD3_k127_5181640_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.495e-197 624.0
HKD3_k127_5181640_3 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 516.0
HKD3_k127_5181640_4 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 465.0
HKD3_k127_5181640_5 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 407.0
HKD3_k127_5181640_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 301.0
HKD3_k127_5181640_7 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 293.0
HKD3_k127_5181640_8 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000004497 218.0
HKD3_k127_5181640_9 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000005484 181.0
HKD3_k127_518406_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1238.0
HKD3_k127_518406_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 582.0
HKD3_k127_518406_10 - - - - 0.000000000000000000000000000000001739 134.0
HKD3_k127_518406_11 membrane - - - 0.0000000000000000000000000000001024 129.0
HKD3_k127_518406_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 477.0
HKD3_k127_518406_3 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 454.0
HKD3_k127_518406_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 464.0
HKD3_k127_518406_5 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
HKD3_k127_518406_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
HKD3_k127_518406_7 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001311 276.0
HKD3_k127_518406_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000009944 245.0
HKD3_k127_518406_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000003777 181.0
HKD3_k127_5196493_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 1.42e-251 790.0
HKD3_k127_5196493_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.249e-240 768.0
HKD3_k127_5196493_10 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 428.0
HKD3_k127_5196493_11 Chromate resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 418.0
HKD3_k127_5196493_12 Rossmann-like domain K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000001843 269.0
HKD3_k127_5196493_13 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 274.0
HKD3_k127_5196493_14 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007384 270.0
HKD3_k127_5196493_15 Transcriptional K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002483 258.0
HKD3_k127_5196493_16 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000005973 234.0
HKD3_k127_5196493_17 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000001688 160.0
HKD3_k127_5196493_18 transcriptional regulator - - - 0.00000000000000000000000000000003881 128.0
HKD3_k127_5196493_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 3.655e-232 728.0
HKD3_k127_5196493_21 Chromate transporter K07240 - - 0.00003487 47.0
HKD3_k127_5196493_3 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 7.445e-217 678.0
HKD3_k127_5196493_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 554.0
HKD3_k127_5196493_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 501.0
HKD3_k127_5196493_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 480.0
HKD3_k127_5196493_7 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 471.0
HKD3_k127_5196493_8 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 486.0
HKD3_k127_5196493_9 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 445.0
HKD3_k127_5219749_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 564.0
HKD3_k127_5219749_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 507.0
HKD3_k127_5219749_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008786 269.0
HKD3_k127_5227321_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1193.0
HKD3_k127_5227321_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 557.0
HKD3_k127_5227321_2 Bacterial regulatory proteins, crp family K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 356.0
HKD3_k127_5227321_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 266.0
HKD3_k127_5227321_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000003035 156.0
HKD3_k127_5228876_0 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
HKD3_k127_5228876_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000153 103.0
HKD3_k127_5228876_2 Bacterial Ig-like domain 2 - - - 0.00000028 63.0
HKD3_k127_5229594_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.583e-217 684.0
HKD3_k127_5229594_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 7.64e-207 653.0
HKD3_k127_5229594_10 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 413.0
HKD3_k127_5229594_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
HKD3_k127_5229594_12 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 366.0
HKD3_k127_5229594_13 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 392.0
HKD3_k127_5229594_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 370.0
HKD3_k127_5229594_15 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 332.0
HKD3_k127_5229594_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 304.0
HKD3_k127_5229594_17 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 271.0
HKD3_k127_5229594_18 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 261.0
HKD3_k127_5229594_19 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 276.0
HKD3_k127_5229594_2 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 582.0
HKD3_k127_5229594_20 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000001046 271.0
HKD3_k127_5229594_21 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000001594 216.0
HKD3_k127_5229594_22 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000716 203.0
HKD3_k127_5229594_23 - - - - 0.00000000000000000000000000000000000000000000000000002126 196.0
HKD3_k127_5229594_25 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000001548 183.0
HKD3_k127_5229594_26 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000006871 158.0
HKD3_k127_5229594_27 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000001164 143.0
HKD3_k127_5229594_28 OmpA family - - - 0.00000000000000000000000000000000601 141.0
HKD3_k127_5229594_29 FecR protein - - - 0.00000000000000000000000000000001839 139.0
HKD3_k127_5229594_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 552.0
HKD3_k127_5229594_30 Transglycosylase associated protein - - - 0.0000000000000000000000000000002958 126.0
HKD3_k127_5229594_31 pyridoxamine 5-phosphate - - - 0.00000000000000000000000005001 119.0
HKD3_k127_5229594_32 Protein of unknown function (DUF3455) - - - 0.00000000000000000000002693 108.0
HKD3_k127_5229594_34 STAS domain K06378 - - 0.00000000000000003179 90.0
HKD3_k127_5229594_35 Protein of unknown function (DUF1289) K06938 - - 0.00000000000000006683 83.0
HKD3_k127_5229594_36 - - - - 0.0000000000008302 81.0
HKD3_k127_5229594_37 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.00000000007374 69.0
HKD3_k127_5229594_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 492.0
HKD3_k127_5229594_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 489.0
HKD3_k127_5229594_6 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 474.0
HKD3_k127_5229594_7 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 450.0
HKD3_k127_5229594_8 Carboxymuconolactone decarboxylase family K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 435.0
HKD3_k127_5229594_9 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 432.0
HKD3_k127_5244500_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.494e-298 922.0
HKD3_k127_5244500_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.19e-264 820.0
HKD3_k127_5244500_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 432.0
HKD3_k127_5244500_11 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 421.0
HKD3_k127_5244500_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 392.0
HKD3_k127_5244500_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000001251 145.0
HKD3_k127_5244500_14 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000000000000000000009483 138.0
HKD3_k127_5244500_15 nucleic-acid-binding protein, contains PIN domain - - - 0.000000000000000000000000000000005929 133.0
HKD3_k127_5244500_16 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000003866 88.0
HKD3_k127_5244500_17 - - - - 0.000000000000004477 78.0
HKD3_k127_5244500_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 2.525e-263 821.0
HKD3_k127_5244500_3 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.553e-256 797.0
HKD3_k127_5244500_4 PFAM FAD dependent oxidoreductase - - - 1.478e-217 681.0
HKD3_k127_5244500_5 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 4.266e-215 674.0
HKD3_k127_5244500_6 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 5.464e-198 647.0
HKD3_k127_5244500_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 511.0
HKD3_k127_5244500_8 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 465.0
HKD3_k127_5244500_9 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 427.0
HKD3_k127_5261159_0 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 602.0
HKD3_k127_5261159_1 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001201 281.0
HKD3_k127_5261159_2 Periplasmic protein thiol K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000001202 238.0
HKD3_k127_5261159_3 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000003081 146.0
HKD3_k127_5261159_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000002628 90.0
HKD3_k127_5305475_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 602.0
HKD3_k127_5305475_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000891 471.0
HKD3_k127_5305475_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
HKD3_k127_5305475_3 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 406.0
HKD3_k127_532852_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.301e-207 668.0
HKD3_k127_532852_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 455.0
HKD3_k127_532852_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 343.0
HKD3_k127_532852_3 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000005432 179.0
HKD3_k127_532852_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000593 134.0
HKD3_k127_532852_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0001025 53.0
HKD3_k127_5349657_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 1.109e-297 940.0
HKD3_k127_5349657_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 381.0
HKD3_k127_5349657_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 383.0
HKD3_k127_5349657_3 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.00000000000000000000000003832 113.0
HKD3_k127_5349657_4 - - - - 0.0000000000000000000005173 104.0
HKD3_k127_5349657_5 - - - - 0.000000000000000000001012 105.0
HKD3_k127_5349657_6 ATP synthase (F/14-kDa) subunit - - - 0.000001017 58.0
HKD3_k127_5416490_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 6.81e-237 737.0
HKD3_k127_5416490_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.815e-195 625.0
HKD3_k127_5416490_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 339.0
HKD3_k127_5416490_3 Pterin binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001205 304.0
HKD3_k127_5417211_0 Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 280.0
HKD3_k127_5417211_1 Protein of unknown function (DUF3623) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006587 280.0
HKD3_k127_5506113_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.368e-194 612.0
HKD3_k127_5506113_1 colicin v production K03558 - - 0.00000000000000000002097 96.0
HKD3_k127_551726_0 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 319.0
HKD3_k127_551726_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004939 282.0
HKD3_k127_551726_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001296 253.0
HKD3_k127_551726_3 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000002428 216.0
HKD3_k127_551726_4 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000007502 180.0
HKD3_k127_551726_5 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000006443 180.0
HKD3_k127_551726_6 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000000000000002618 170.0
HKD3_k127_551726_7 Voltage gated chloride channel - - - 0.000000000000000000000000000001886 123.0
HKD3_k127_551726_8 epimerase - - - 0.0007406 50.0
HKD3_k127_552634_0 CHAT domain - - - 0.0 1418.0
HKD3_k127_552634_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.653e-320 999.0
HKD3_k127_552634_10 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 405.0
HKD3_k127_552634_11 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 395.0
HKD3_k127_552634_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 407.0
HKD3_k127_552634_13 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 376.0
HKD3_k127_552634_14 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 364.0
HKD3_k127_552634_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 360.0
HKD3_k127_552634_16 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 366.0
HKD3_k127_552634_17 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 341.0
HKD3_k127_552634_18 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 362.0
HKD3_k127_552634_19 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 312.0
HKD3_k127_552634_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.736e-236 735.0
HKD3_k127_552634_20 phytoene K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 308.0
HKD3_k127_552634_21 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 310.0
HKD3_k127_552634_22 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 304.0
HKD3_k127_552634_23 PFAM Transposase K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
HKD3_k127_552634_24 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000006779 272.0
HKD3_k127_552634_25 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000007052 222.0
HKD3_k127_552634_26 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
HKD3_k127_552634_27 PFAM Peptidase M15A - - - 0.00000000000000000000000000000000000000000000000000001637 219.0
HKD3_k127_552634_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000005978 211.0
HKD3_k127_552634_29 PFAM Patatin - - - 0.000000000000000000000000000000000000000000000001597 176.0
HKD3_k127_552634_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 7.669e-220 688.0
HKD3_k127_552634_30 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000005649 165.0
HKD3_k127_552634_31 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000003938 159.0
HKD3_k127_552634_32 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000001304 160.0
HKD3_k127_552634_33 Peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000006948 161.0
HKD3_k127_552634_34 FOG TPR repeat - - - 0.000000000000000000000000000000000000002577 169.0
HKD3_k127_552634_35 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000005842 150.0
HKD3_k127_552634_36 Cold shock protein K03704 - - 0.000000000000000000000000000000009901 134.0
HKD3_k127_552634_37 TIR domain - - - 0.000000000000000000000001173 113.0
HKD3_k127_552634_38 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000007458 113.0
HKD3_k127_552634_39 Belongs to the UPF0434 family K09791 - - 0.00000000000000000004875 91.0
HKD3_k127_552634_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.16e-213 670.0
HKD3_k127_552634_40 PFAM OmpA MotB domain protein - - - 0.0000000000000001281 85.0
HKD3_k127_552634_41 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000004209 82.0
HKD3_k127_552634_42 DNA integration - - - 0.0000004734 52.0
HKD3_k127_552634_43 - - - - 0.0006436 46.0
HKD3_k127_552634_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.205e-205 646.0
HKD3_k127_552634_6 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.793e-196 632.0
HKD3_k127_552634_7 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 550.0
HKD3_k127_552634_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 459.0
HKD3_k127_552634_9 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 411.0
HKD3_k127_5532166_0 Zn-ribbon protein possibly nucleic acid-binding - - - 0.0 1240.0
HKD3_k127_5532166_1 ribosome binding - - - 1.258e-279 893.0
HKD3_k127_5532166_10 Outer Membrane Lipoprotein K06077 - - 0.000000000000000000000000000000000000000000000001799 178.0
HKD3_k127_5532166_11 Plasmid maintenance system killer K07334 - - 0.0000000000000000000001113 100.0
HKD3_k127_5532166_13 - - - - 0.00000001112 60.0
HKD3_k127_5532166_2 ATPase involved in DNA repair - - - 8.435e-251 817.0
HKD3_k127_5532166_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 608.0
HKD3_k127_5532166_4 Belongs to the peptidase S1B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 594.0
HKD3_k127_5532166_5 Isoleucyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 532.0
HKD3_k127_5532166_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 307.0
HKD3_k127_5532166_7 Glycosyl hydrolase 108 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 286.0
HKD3_k127_5532166_8 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000825 244.0
HKD3_k127_5532166_9 - - - - 0.00000000000000000000000000000000000000000000000000006263 199.0
HKD3_k127_5546612_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 404.0
HKD3_k127_5546612_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 240.0
HKD3_k127_5546612_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000001383 110.0
HKD3_k127_5553598_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.409e-278 871.0
HKD3_k127_5553598_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 2.239e-205 650.0
HKD3_k127_5553598_2 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 406.0
HKD3_k127_5553598_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 325.0
HKD3_k127_5553598_4 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000008099 187.0
HKD3_k127_5569300_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 578.0
HKD3_k127_5569300_1 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000009513 201.0
HKD3_k127_5584151_0 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000004991 190.0
HKD3_k127_5584151_1 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000003003 175.0
HKD3_k127_5601255_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.442e-224 703.0
HKD3_k127_5601255_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 569.0
HKD3_k127_5601255_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 396.0
HKD3_k127_5601255_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000004118 271.0
HKD3_k127_5601255_4 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001176 260.0
HKD3_k127_5601255_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006051 252.0
HKD3_k127_5601255_6 Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000001932 209.0
HKD3_k127_5601255_7 - - - - 0.0000000000000006609 87.0
HKD3_k127_560812_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 360.0
HKD3_k127_560812_1 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 294.0
HKD3_k127_560812_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000008382 128.0
HKD3_k127_560812_11 Protein of unknown function (DUF2721) - - - 0.00000000000000000000001719 114.0
HKD3_k127_560812_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000009368 94.0
HKD3_k127_560812_13 toxin-antitoxin pair type II binding - - - 0.000006464 51.0
HKD3_k127_560812_2 receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002793 301.0
HKD3_k127_560812_3 Biopolymer transport K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 263.0
HKD3_k127_560812_4 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002832 267.0
HKD3_k127_560812_5 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000005942 247.0
HKD3_k127_560812_6 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000001671 193.0
HKD3_k127_560812_7 Biopolymer transport K03559 - - 0.0000000000000000000000000000000000000005205 155.0
HKD3_k127_560812_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000549 138.0
HKD3_k127_560812_9 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000000001643 135.0
HKD3_k127_5661084_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1109.0
HKD3_k127_5661084_1 amidohydrolase K01451 - 3.5.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 559.0
HKD3_k127_5661084_2 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000003223 227.0
HKD3_k127_5661084_3 DinB family - - - 0.0000000000000000000000000000000000000000000000000002395 196.0
HKD3_k127_5661084_4 GCN5 family acetyltransferase - - - 0.000000000000000000000000009696 123.0
HKD3_k127_56782_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1010.0
HKD3_k127_56782_1 Dehydratase family K13875 - 4.2.1.25 5.417e-299 927.0
HKD3_k127_56782_10 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 499.0
HKD3_k127_56782_11 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 470.0
HKD3_k127_56782_12 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 467.0
HKD3_k127_56782_13 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 460.0
HKD3_k127_56782_14 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 470.0
HKD3_k127_56782_15 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 441.0
HKD3_k127_56782_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 460.0
HKD3_k127_56782_17 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 443.0
HKD3_k127_56782_18 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 440.0
HKD3_k127_56782_19 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 458.0
HKD3_k127_56782_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.981e-256 809.0
HKD3_k127_56782_20 Malate/L-lactate dehydrogenase K00016,K00073 - 1.1.1.27,1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 436.0
HKD3_k127_56782_21 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 404.0
HKD3_k127_56782_22 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 345.0
HKD3_k127_56782_23 MotA TolQ ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 300.0
HKD3_k127_56782_24 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 306.0
HKD3_k127_56782_25 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002734 282.0
HKD3_k127_56782_26 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000436 275.0
HKD3_k127_56782_27 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001553 280.0
HKD3_k127_56782_28 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HKD3_k127_56782_29 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000001006 234.0
HKD3_k127_56782_3 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 2.951e-232 753.0
HKD3_k127_56782_30 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
HKD3_k127_56782_31 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000003445 204.0
HKD3_k127_56782_32 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000001707 188.0
HKD3_k127_56782_33 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000009285 184.0
HKD3_k127_56782_34 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.00000000000000000000000000000000000000174 170.0
HKD3_k127_56782_35 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000412 153.0
HKD3_k127_56782_36 Acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000003232 145.0
HKD3_k127_56782_37 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000002687 144.0
HKD3_k127_56782_38 Protein of unknown function (DUF504) - - - 0.000000000000000000000003579 105.0
HKD3_k127_56782_39 TonB C terminal K03646 - - 0.000000000000000000001347 109.0
HKD3_k127_56782_4 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.474e-223 710.0
HKD3_k127_56782_40 - - - - 0.00000000000003711 76.0
HKD3_k127_56782_5 Bacterial extracellular solute-binding protein K02027 - - 4.235e-209 659.0
HKD3_k127_56782_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 567.0
HKD3_k127_56782_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 537.0
HKD3_k127_56782_8 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 524.0
HKD3_k127_56782_9 ABC-type sugar K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 507.0
HKD3_k127_5680_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001425 272.0
HKD3_k127_5680_1 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000002404 184.0
HKD3_k127_5680_2 Glycine-zipper domain - - - 0.000000000000000000000000000000000001179 146.0
HKD3_k127_5692609_0 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 625.0
HKD3_k127_5692609_1 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 584.0
HKD3_k127_5692609_10 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HKD3_k127_5692609_11 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007588 250.0
HKD3_k127_5692609_12 toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000001535 233.0
HKD3_k127_5692609_13 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000001461 207.0
HKD3_k127_5692609_14 Sodium/glutamate symporter K03312 - - 0.000000000000000000000000000000000000000000000000000000001496 216.0
HKD3_k127_5692609_15 Cupin 2, conserved barrel domain protein K00450,K00971,K09988,K11312 - 1.13.11.4,2.7.7.13,5.3.1.15 0.00000000000000000000000000000000000000005237 169.0
HKD3_k127_5692609_16 - - - - 0.0000000000000006848 82.0
HKD3_k127_5692609_17 Glycine zipper 2TM domain - - - 0.00000000000001848 79.0
HKD3_k127_5692609_18 STAS domain K07122 - - 0.00000000001551 68.0
HKD3_k127_5692609_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 475.0
HKD3_k127_5692609_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 444.0
HKD3_k127_5692609_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 458.0
HKD3_k127_5692609_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 405.0
HKD3_k127_5692609_6 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
HKD3_k127_5692609_7 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 388.0
HKD3_k127_5692609_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 375.0
HKD3_k127_5692609_9 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 337.0
HKD3_k127_5740877_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 490.0
HKD3_k127_5740877_1 Thioredoxin domain - - - 0.0000000000000000000000002028 120.0
HKD3_k127_5740877_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000001995 50.0
HKD3_k127_5763578_0 ammonium transporter K03320 - - 2.059e-217 685.0
HKD3_k127_5763578_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.309e-194 613.0
HKD3_k127_5763578_10 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000003014 211.0
HKD3_k127_5763578_11 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000001019 201.0
HKD3_k127_5763578_12 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000007348 178.0
HKD3_k127_5763578_13 Zn-dependent protease with chaperone function K07387 - - 0.00000000000000000000000000000000000000002209 163.0
HKD3_k127_5763578_14 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.0000000000000000000000000000000000004707 144.0
HKD3_k127_5763578_15 Phosphotransferase System K11189 - - 0.00000000000000000006836 92.0
HKD3_k127_5763578_16 Membrane fusogenic activity K09806 - - 0.000000000000000001344 89.0
HKD3_k127_5763578_17 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000001607 66.0
HKD3_k127_5763578_2 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 568.0
HKD3_k127_5763578_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 548.0
HKD3_k127_5763578_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
HKD3_k127_5763578_5 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 292.0
HKD3_k127_5763578_6 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 293.0
HKD3_k127_5763578_7 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007284 258.0
HKD3_k127_5763578_8 Auxin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000003325 215.0
HKD3_k127_5763578_9 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000003701 209.0
HKD3_k127_5785884_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1024.0
HKD3_k127_5785884_1 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 2.583e-261 829.0
HKD3_k127_5785884_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 466.0
HKD3_k127_5785884_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 465.0
HKD3_k127_5785884_12 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 461.0
HKD3_k127_5785884_13 Male sterility protein K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 451.0
HKD3_k127_5785884_14 Protein of unknown function (DUF1116) K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 455.0
HKD3_k127_5785884_15 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 425.0
HKD3_k127_5785884_16 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 394.0
HKD3_k127_5785884_17 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 385.0
HKD3_k127_5785884_18 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 394.0
HKD3_k127_5785884_19 FCD K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 347.0
HKD3_k127_5785884_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 6.614e-252 783.0
HKD3_k127_5785884_20 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 333.0
HKD3_k127_5785884_21 FdrA family K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 340.0
HKD3_k127_5785884_22 FdrA family K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 339.0
HKD3_k127_5785884_23 Tripartite ATP-independent periplasmic transporter, DctQ K21394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
HKD3_k127_5785884_24 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000003374 234.0
HKD3_k127_5785884_25 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000000000000005641 216.0
HKD3_k127_5785884_26 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000009025 151.0
HKD3_k127_5785884_27 Protein of unknown function (DUF2877) - - - 0.0000000000000000000000000000000000001097 163.0
HKD3_k127_5785884_28 Glycine cleavage H-protein - - - 0.0000000000000000000007077 103.0
HKD3_k127_5785884_29 DsrE/DsrF-like family K07092 - - 0.0000000000000008743 84.0
HKD3_k127_5785884_3 TRAP C4-dicarboxylate transport system permease DctM subunit K11690,K21393 - - 2.513e-230 727.0
HKD3_k127_5785884_30 - - - - 0.00000000000002867 76.0
HKD3_k127_5785884_31 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.0000003718 58.0
HKD3_k127_5785884_4 MOFRL family K11529 - 2.7.1.165 8.052e-198 628.0
HKD3_k127_5785884_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.538e-197 622.0
HKD3_k127_5785884_6 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 578.0
HKD3_k127_5785884_7 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 537.0
HKD3_k127_5785884_8 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 529.0
HKD3_k127_5785884_9 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 482.0
HKD3_k127_5795899_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.86e-238 749.0
HKD3_k127_5795899_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000002944 187.0
HKD3_k127_5795899_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000004727 98.0
HKD3_k127_5795899_3 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000003748 76.0
HKD3_k127_5823276_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1654.0
HKD3_k127_5823276_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.746e-242 772.0
HKD3_k127_5823276_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001573 74.0
HKD3_k127_5823276_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 601.0
HKD3_k127_5823276_3 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 360.0
HKD3_k127_5823276_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 309.0
HKD3_k127_5823276_5 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007402 263.0
HKD3_k127_5823276_6 - - - - 0.00000000000000000000000000000000000000000000001556 182.0
HKD3_k127_5823276_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000006906 166.0
HKD3_k127_5823276_8 Cytochrome c - - - 0.000000000000000000000000000000001825 149.0
HKD3_k127_5823276_9 cytochrome - - - 0.00000000000000000000000007045 115.0
HKD3_k127_595535_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1338.0
HKD3_k127_595535_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 304.0
HKD3_k127_595535_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009962 259.0
HKD3_k127_595535_3 PFAM regulatory protein TetR K03577 - - 0.000000000000000000000000000000000000000000000000000000649 201.0
HKD3_k127_599705_0 Amidohydrolase family K01464 - 3.5.2.2 3.608e-225 739.0
HKD3_k127_599705_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 9.6e-220 691.0
HKD3_k127_599705_10 Branched-chain amino acid ATP-binding cassette transporter K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 387.0
HKD3_k127_599705_11 Multicopper oxidase K04753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 362.0
HKD3_k127_599705_12 ABC transporter K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 321.0
HKD3_k127_599705_13 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 300.0
HKD3_k127_599705_14 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003475 261.0
HKD3_k127_599705_15 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005628 245.0
HKD3_k127_599705_16 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004423 247.0
HKD3_k127_599705_17 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002893 253.0
HKD3_k127_599705_18 C4-dicarboxylate ABC transporter, substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000006204 224.0
HKD3_k127_599705_19 dehydratase - - - 0.0000000000000000000000000000000000000000000005752 179.0
HKD3_k127_599705_2 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.096e-200 629.0
HKD3_k127_599705_20 Histidine kinase - - - 0.0000000000000000000000000000000000000000001216 175.0
HKD3_k127_599705_21 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000000000000000005803 123.0
HKD3_k127_599705_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000005784 132.0
HKD3_k127_599705_23 protein SCO1 SenC K07152 - - 0.0000000000000000000000000001998 126.0
HKD3_k127_599705_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000004202 95.0
HKD3_k127_599705_25 Peptidase family M23 - - - 0.000000000000001051 91.0
HKD3_k127_599705_26 Histidine kinase internal region - - - 0.00000000000000776 87.0
HKD3_k127_599705_27 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000004205 70.0
HKD3_k127_599705_28 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000001815 60.0
HKD3_k127_599705_29 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000001117 52.0
HKD3_k127_599705_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 555.0
HKD3_k127_599705_4 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 546.0
HKD3_k127_599705_5 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 552.0
HKD3_k127_599705_6 Branched-chain amino acid transport system / permease component K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 522.0
HKD3_k127_599705_7 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 392.0
HKD3_k127_599705_8 Asp/Glu/Hydantoin racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 380.0
HKD3_k127_599705_9 transcriptional Regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 373.0
HKD3_k127_6017707_0 Domain related to MnhB subunit of Na+/H+ antiporter K00341,K05559 - 1.6.5.3 2.56e-316 991.0
HKD3_k127_6017707_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.079e-242 760.0
HKD3_k127_6017707_2 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 569.0
HKD3_k127_6017707_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 507.0
HKD3_k127_6017707_4 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K00342,K05561,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 458.0
HKD3_k127_6017707_5 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 418.0
HKD3_k127_6017707_6 Na+/H+ ion antiporter subunit - - - 0.0000000000000000000000000000000000000000000000000000001699 217.0
HKD3_k127_6017707_7 NADH-ubiquinone oxidoreductase subunit 4L K05560 - - 0.000000000000000000000000000000000001571 149.0
HKD3_k127_6017707_8 COG1320 Multisubunit Na H antiporter, MnhG subunit K05564 - - 0.0000000000000000000000000000000001629 136.0
HKD3_k127_6017707_9 Multisubunit Na H antiporter, MnhF subunit K05563 - - 0.0000000000000000000000283 110.0
HKD3_k127_6049539_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000004979 121.0
HKD3_k127_6049539_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000006774 121.0
HKD3_k127_6049539_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000003388 51.0
HKD3_k127_6049539_3 PDZ domain (Also known as DHR or GLGF) - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000008301 60.0
HKD3_k127_6049539_4 - - - - 0.00000196 59.0
HKD3_k127_6093507_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 1.266e-286 888.0
HKD3_k127_6093507_1 FtsX-like permease family K02004 - - 4.471e-263 847.0
HKD3_k127_6093507_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 384.0
HKD3_k127_6093507_11 Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 362.0
HKD3_k127_6093507_12 Aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000004539 238.0
HKD3_k127_6093507_13 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000004838 212.0
HKD3_k127_6093507_14 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000004217 180.0
HKD3_k127_6093507_15 cell redox homeostasis - - - 0.0000000000000000000000000000000000000002474 156.0
HKD3_k127_6093507_16 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000008201 89.0
HKD3_k127_6093507_2 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 573.0
HKD3_k127_6093507_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 505.0
HKD3_k127_6093507_4 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 498.0
HKD3_k127_6093507_5 DNA recombination protein, rmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 483.0
HKD3_k127_6093507_6 Guanine deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 471.0
HKD3_k127_6093507_7 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 447.0
HKD3_k127_6093507_8 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 400.0
HKD3_k127_6093507_9 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 403.0
HKD3_k127_6108526_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001096 230.0
HKD3_k127_6108526_1 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000000004033 190.0
HKD3_k127_6108526_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000002462 179.0
HKD3_k127_6117755_0 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000001479 218.0
HKD3_k127_6117755_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000004559 136.0
HKD3_k127_6117755_2 RNB K01147 - 3.1.13.1 0.0000000000204 67.0
HKD3_k127_6143201_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1405.0
HKD3_k127_6143201_1 efflux pump K18138 - - 0.0 1362.0
HKD3_k127_6143201_10 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 458.0
HKD3_k127_6143201_11 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 438.0
HKD3_k127_6143201_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 421.0
HKD3_k127_6143201_13 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 379.0
HKD3_k127_6143201_14 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 380.0
HKD3_k127_6143201_15 transport system periplasmic component K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
HKD3_k127_6143201_16 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 328.0
HKD3_k127_6143201_17 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 326.0
HKD3_k127_6143201_18 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 305.0
HKD3_k127_6143201_19 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 294.0
HKD3_k127_6143201_2 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 1.356e-302 936.0
HKD3_k127_6143201_20 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 267.0
HKD3_k127_6143201_21 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000113 252.0
HKD3_k127_6143201_22 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
HKD3_k127_6143201_23 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000006069 231.0
HKD3_k127_6143201_24 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000005849 207.0
HKD3_k127_6143201_25 - - - - 0.000000000000000000000000000000000000000003074 164.0
HKD3_k127_6143201_26 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000004484 173.0
HKD3_k127_6143201_27 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000003541 137.0
HKD3_k127_6143201_28 DNA polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000001365 129.0
HKD3_k127_6143201_29 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000004133 124.0
HKD3_k127_6143201_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.799e-241 751.0
HKD3_k127_6143201_4 transport system fused permease components - - - 4.384e-227 737.0
HKD3_k127_6143201_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 574.0
HKD3_k127_6143201_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 547.0
HKD3_k127_6143201_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 519.0
HKD3_k127_6143201_8 membrane protein terc K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 505.0
HKD3_k127_6143201_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 514.0
HKD3_k127_6144525_0 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001636 283.0
HKD3_k127_6144525_1 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.000000000000000000000003657 116.0
HKD3_k127_6144914_0 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 528.0
HKD3_k127_6144914_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 494.0
HKD3_k127_6144914_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000004752 248.0
HKD3_k127_6165848_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1322.0
HKD3_k127_6165848_1 belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 3.636e-242 756.0
HKD3_k127_6165848_10 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000006563 175.0
HKD3_k127_6165848_11 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.0000003622 52.0
HKD3_k127_6165848_2 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 531.0
HKD3_k127_6165848_3 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 505.0
HKD3_k127_6165848_4 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 496.0
HKD3_k127_6165848_5 HI0933-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 471.0
HKD3_k127_6165848_6 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 364.0
HKD3_k127_6165848_7 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 354.0
HKD3_k127_6165848_8 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 298.0
HKD3_k127_6165848_9 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000198 180.0
HKD3_k127_6172496_0 Glycosyl hydrolases family 15 - - - 5.009e-288 897.0
HKD3_k127_6172496_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 6.234e-215 678.0
HKD3_k127_6172496_2 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 417.0
HKD3_k127_6172496_3 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 395.0
HKD3_k127_6172496_4 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005133 248.0
HKD3_k127_6172496_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000004191 210.0
HKD3_k127_6172496_6 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000000000000000000002841 200.0
HKD3_k127_6172496_7 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000044 192.0
HKD3_k127_6172496_8 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000000000002062 132.0
HKD3_k127_6173424_0 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 499.0
HKD3_k127_6173424_1 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 316.0
HKD3_k127_6173424_2 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007785 276.0
HKD3_k127_6174359_0 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 394.0
HKD3_k127_6174359_1 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 343.0
HKD3_k127_6174359_2 Low molecular weight phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003927 245.0
HKD3_k127_6174359_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000003219 141.0
HKD3_k127_6177887_0 A predicted alpha-helical domain with a conserved ER motif. - - - 2.117e-267 847.0
HKD3_k127_6177887_1 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 359.0
HKD3_k127_6177887_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000117 57.0
HKD3_k127_6177887_2 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 306.0
HKD3_k127_6177887_3 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 301.0
HKD3_k127_6177887_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
HKD3_k127_6177887_5 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001734 276.0
HKD3_k127_6177887_6 transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003199 250.0
HKD3_k127_6177887_7 Protein of unknown function (DUF2853) - - - 0.0000000000000000000000000000000004064 136.0
HKD3_k127_6177887_8 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000003034 121.0
HKD3_k127_6177887_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000003065 106.0
HKD3_k127_6191353_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1985.0
HKD3_k127_6193701_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.174e-292 904.0
HKD3_k127_6193701_1 protein conserved in bacteria K07793 - - 1.253e-240 752.0
HKD3_k127_6193701_10 Fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 325.0
HKD3_k127_6193701_11 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 343.0
HKD3_k127_6193701_12 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 276.0
HKD3_k127_6193701_13 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000004522 181.0
HKD3_k127_6193701_14 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000008737 156.0
HKD3_k127_6193701_2 AMP-binding enzyme C-terminal domain - - - 2.71e-232 728.0
HKD3_k127_6193701_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 510.0
HKD3_k127_6193701_4 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 500.0
HKD3_k127_6193701_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179,K08941 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 496.0
HKD3_k127_6193701_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 445.0
HKD3_k127_6193701_7 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 390.0
HKD3_k127_6193701_8 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 378.0
HKD3_k127_6193701_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 379.0
HKD3_k127_6193946_0 Aminotransferase K14287 - 2.6.1.88 0.0000000000000000000000000000000000000000000000000002561 188.0
HKD3_k127_6193946_1 Putative lipopolysaccharide-modifying enzyme. - - - 0.000000000006504 78.0
HKD3_k127_6193946_2 nucleic acid-binding protein, contains PIN domain - - - 0.0000001086 55.0
HKD3_k127_6207806_0 Peptidase C39 family K13409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002539 270.0
HKD3_k127_6207806_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000002217 232.0
HKD3_k127_6213368_0 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000002735 239.0
HKD3_k127_6213368_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0000000000000000001163 94.0
HKD3_k127_6213368_2 response regulator K02667 - - 0.00000000004552 66.0
HKD3_k127_6258534_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.067e-288 901.0
HKD3_k127_6258534_1 Nuclease-related domain - - - 2.066e-200 637.0
HKD3_k127_6258534_10 Putative cyclase - - - 0.0000000000003384 76.0
HKD3_k127_6258534_11 Arylsulfatase K01130,K01138 - 3.1.6.1 0.0000000001112 64.0
HKD3_k127_6258534_2 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 569.0
HKD3_k127_6258534_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 440.0
HKD3_k127_6258534_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 323.0
HKD3_k127_6258534_5 - - - - 0.0000000000000000000000000000000000000000000000000000000002265 217.0
HKD3_k127_6258534_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003266 203.0
HKD3_k127_6258534_8 Universal stress protein - - - 0.00000000000000000000000036 110.0
HKD3_k127_6258534_9 Protein of unknown function (DUF1778) - - - 0.0000000000000000002499 93.0
HKD3_k127_6270341_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.121e-319 985.0
HKD3_k127_6270341_1 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 576.0
HKD3_k127_6270341_10 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000006878 142.0
HKD3_k127_6270341_11 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 0.00000000000000003512 84.0
HKD3_k127_6270341_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 462.0
HKD3_k127_6270341_3 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 431.0
HKD3_k127_6270341_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 301.0
HKD3_k127_6270341_5 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 299.0
HKD3_k127_6270341_6 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000000000000000000000000000000000000000000005319 226.0
HKD3_k127_6270341_7 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000002061 234.0
HKD3_k127_6270341_8 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000006366 225.0
HKD3_k127_6270341_9 - - - - 0.00000000000000000000000000000000000000000006826 166.0
HKD3_k127_6272954_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 534.0
HKD3_k127_6272954_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 512.0
HKD3_k127_6272954_2 Domain of unknown function (DUF3394) - - - 0.00000000000000000000000000000000000000000000000000001825 193.0
HKD3_k127_6272954_3 Belongs to the DnaA family K10763 - - 0.000000000000000000000000000000000000000000000000000195 198.0
HKD3_k127_6272954_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000008072 93.0
HKD3_k127_6284633_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 2.095e-317 989.0
HKD3_k127_6284633_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 3.254e-310 964.0
HKD3_k127_6284633_10 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 609.0
HKD3_k127_6284633_11 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 564.0
HKD3_k127_6284633_12 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 535.0
HKD3_k127_6284633_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 537.0
HKD3_k127_6284633_14 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
HKD3_k127_6284633_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 476.0
HKD3_k127_6284633_16 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 488.0
HKD3_k127_6284633_17 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 470.0
HKD3_k127_6284633_18 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 440.0
HKD3_k127_6284633_19 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 467.0
HKD3_k127_6284633_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.131e-284 896.0
HKD3_k127_6284633_20 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 425.0
HKD3_k127_6284633_21 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 421.0
HKD3_k127_6284633_22 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 413.0
HKD3_k127_6284633_23 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 395.0
HKD3_k127_6284633_24 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HKD3_k127_6284633_25 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 376.0
HKD3_k127_6284633_26 Histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 366.0
HKD3_k127_6284633_27 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 368.0
HKD3_k127_6284633_28 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 314.0
HKD3_k127_6284633_29 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 307.0
HKD3_k127_6284633_3 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.297e-264 819.0
HKD3_k127_6284633_30 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 313.0
HKD3_k127_6284633_31 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001721 282.0
HKD3_k127_6284633_32 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001921 283.0
HKD3_k127_6284633_33 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
HKD3_k127_6284633_34 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005559 273.0
HKD3_k127_6284633_35 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005663 284.0
HKD3_k127_6284633_36 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001277 269.0
HKD3_k127_6284633_37 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000005894 261.0
HKD3_k127_6284633_38 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
HKD3_k127_6284633_39 - - - - 0.0000000000000000000000000000000000000000000000000008343 196.0
HKD3_k127_6284633_4 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.674e-227 717.0
HKD3_k127_6284633_40 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000001188 179.0
HKD3_k127_6284633_41 PGAP1-like protein - - - 0.000000000000000000000000000000000000000001876 172.0
HKD3_k127_6284633_42 RES - - - 0.000000000000000000000000000000000000003653 150.0
HKD3_k127_6284633_43 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000008713 138.0
HKD3_k127_6284633_44 - - - - 0.0000000000000000000000000000000007155 137.0
HKD3_k127_6284633_45 glycosyl transferase group 1 - - - 0.000000000000000000000000000000006903 144.0
HKD3_k127_6284633_46 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000000404 128.0
HKD3_k127_6284633_47 RDD family - - - 0.000000000000000000000000000005248 126.0
HKD3_k127_6284633_48 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000005979 117.0
HKD3_k127_6284633_49 Protein of unknown function (DUF2384) - - - 0.00000000000000000000001569 105.0
HKD3_k127_6284633_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.827e-215 685.0
HKD3_k127_6284633_50 Protein of unknown function (DUF3106) - - - 0.0000000000000000000004177 104.0
HKD3_k127_6284633_51 - - - - 0.000000000000002905 77.0
HKD3_k127_6284633_52 - - - - 0.000000000000003105 77.0
HKD3_k127_6284633_53 Protein of unknown function (DUF3619) - - - 0.000000000000006183 87.0
HKD3_k127_6284633_54 - - - - 0.0000000086 61.0
HKD3_k127_6284633_6 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 2.101e-214 683.0
HKD3_k127_6284633_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 8.524e-214 698.0
HKD3_k127_6284633_8 nitrogen regulation protein K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.504e-204 662.0
HKD3_k127_6284633_9 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 618.0
HKD3_k127_6328924_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1459.0
HKD3_k127_6328924_1 COG2366 Protein related to penicillin acylase K07116 - 3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 644.0
HKD3_k127_6328924_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 456.0
HKD3_k127_6328924_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 334.0
HKD3_k127_6328924_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 315.0
HKD3_k127_6328924_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
HKD3_k127_6328924_6 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000001857 190.0
HKD3_k127_6328924_7 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000001658 179.0
HKD3_k127_6356497_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 611.0
HKD3_k127_6356497_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 518.0
HKD3_k127_6356497_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 474.0
HKD3_k127_6356497_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 370.0
HKD3_k127_6356497_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000004293 203.0
HKD3_k127_6387041_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.42e-251 783.0
HKD3_k127_6387041_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.636e-245 773.0
HKD3_k127_6387041_10 COG0277 FAD FMN-containing dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 576.0
HKD3_k127_6387041_11 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
HKD3_k127_6387041_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 482.0
HKD3_k127_6387041_13 cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 481.0
HKD3_k127_6387041_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 444.0
HKD3_k127_6387041_15 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 428.0
HKD3_k127_6387041_16 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 398.0
HKD3_k127_6387041_17 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 396.0
HKD3_k127_6387041_18 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 366.0
HKD3_k127_6387041_19 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 357.0
HKD3_k127_6387041_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.726e-244 761.0
HKD3_k127_6387041_20 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
HKD3_k127_6387041_21 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 348.0
HKD3_k127_6387041_22 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 352.0
HKD3_k127_6387041_23 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 321.0
HKD3_k127_6387041_24 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
HKD3_k127_6387041_25 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001016 282.0
HKD3_k127_6387041_26 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
HKD3_k127_6387041_27 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002981 276.0
HKD3_k127_6387041_28 PFAM Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000104 261.0
HKD3_k127_6387041_29 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001148 269.0
HKD3_k127_6387041_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 9.879e-228 712.0
HKD3_k127_6387041_30 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
HKD3_k127_6387041_31 FAD dependent oxidoreductase K06955 - - 0.0000000000000000000000000000000000000000000000000000000000000003747 231.0
HKD3_k127_6387041_32 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000529 238.0
HKD3_k127_6387041_33 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000002173 224.0
HKD3_k127_6387041_34 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
HKD3_k127_6387041_35 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009029 233.0
HKD3_k127_6387041_36 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
HKD3_k127_6387041_37 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000002729 205.0
HKD3_k127_6387041_38 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000001641 202.0
HKD3_k127_6387041_39 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000009244 203.0
HKD3_k127_6387041_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 2.685e-222 698.0
HKD3_k127_6387041_40 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000002354 207.0
HKD3_k127_6387041_41 HD domain - - - 0.000000000000000000000000000000000000000000000000000007145 196.0
HKD3_k127_6387041_42 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000008138 199.0
HKD3_k127_6387041_43 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000003374 187.0
HKD3_k127_6387041_44 Dioxygenase K00449 - 1.13.11.3 0.000000000000000000000000000000000000000112 163.0
HKD3_k127_6387041_45 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002375 142.0
HKD3_k127_6387041_46 - - - - 0.0000000000000000000000000000000003678 139.0
HKD3_k127_6387041_47 thioesterase K07107 - - 0.000000000000000000000000000000008081 141.0
HKD3_k127_6387041_48 - - - - 0.000000000000000000000000000001427 124.0
HKD3_k127_6387041_49 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000004381 123.0
HKD3_k127_6387041_5 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.242e-214 683.0
HKD3_k127_6387041_50 - - - - 0.0000000000000000000000000113 111.0
HKD3_k127_6387041_51 - - - - 0.0000000000000000000000004945 115.0
HKD3_k127_6387041_52 Protein of unknown function (DUF2788) - - - 0.00000000000000000000004888 108.0
HKD3_k127_6387041_53 colicin v production K03558 - - 0.0000000000000000000003354 104.0
HKD3_k127_6387041_54 Sporulation related domain K03749 - - 0.000000000000000002033 94.0
HKD3_k127_6387041_55 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000003495 62.0
HKD3_k127_6387041_56 PFAM Uncharacterised protein family UPF0150 - - - 0.0000008759 59.0
HKD3_k127_6387041_57 Activator of Hsp90 ATPase 1 family protein - - - 0.00002173 48.0
HKD3_k127_6387041_58 - - - - 0.0005911 49.0
HKD3_k127_6387041_6 Belongs to the glycosyl hydrolase 57 family - - - 1.061e-213 701.0
HKD3_k127_6387041_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 577.0
HKD3_k127_6387041_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 576.0
HKD3_k127_6387041_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 569.0
HKD3_k127_6423689_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.943e-252 794.0
HKD3_k127_6423689_1 Magnesium transport protein CorA - - - 1.602e-236 743.0
HKD3_k127_6423689_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 329.0
HKD3_k127_6423689_11 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 313.0
HKD3_k127_6423689_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002027 241.0
HKD3_k127_6423689_2 acyl-CoA dehydrogenase K11731 - - 1.61e-197 621.0
HKD3_k127_6423689_3 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 519.0
HKD3_k127_6423689_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 475.0
HKD3_k127_6423689_5 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 474.0
HKD3_k127_6423689_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 413.0
HKD3_k127_6423689_7 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 397.0
HKD3_k127_6423689_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 361.0
HKD3_k127_6423689_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 352.0
HKD3_k127_6458747_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1008.0
HKD3_k127_6458747_1 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 2.131e-307 954.0
HKD3_k127_6458747_10 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 492.0
HKD3_k127_6458747_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 486.0
HKD3_k127_6458747_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 366.0
HKD3_k127_6458747_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 355.0
HKD3_k127_6458747_14 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 337.0
HKD3_k127_6458747_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 333.0
HKD3_k127_6458747_16 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 345.0
HKD3_k127_6458747_17 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 301.0
HKD3_k127_6458747_18 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 312.0
HKD3_k127_6458747_19 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 309.0
HKD3_k127_6458747_2 Peptidase family M3 K01414 - 3.4.24.70 2.365e-287 897.0
HKD3_k127_6458747_20 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
HKD3_k127_6458747_21 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002761 274.0
HKD3_k127_6458747_22 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000000000000000000002987 229.0
HKD3_k127_6458747_23 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000455 203.0
HKD3_k127_6458747_24 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000008697 192.0
HKD3_k127_6458747_25 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001479 180.0
HKD3_k127_6458747_26 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.000000000000000000000000000000000000000000000006702 185.0
HKD3_k127_6458747_27 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000004923 171.0
HKD3_k127_6458747_28 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000007518 169.0
HKD3_k127_6458747_29 Transposase - - - 0.00000000000000000000000000000000000002415 156.0
HKD3_k127_6458747_3 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.936e-249 778.0
HKD3_k127_6458747_30 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000001285 145.0
HKD3_k127_6458747_31 PFAM Glutaredoxin - - - 0.000000000000000000000000000000005182 139.0
HKD3_k127_6458747_32 phenylacetic acid degradation protein paaD K02614 - - 0.00000000000000000000000000007939 129.0
HKD3_k127_6458747_33 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000378 94.0
HKD3_k127_6458747_34 Plasmid stability protein K21495 - - 0.0000000000000000007296 87.0
HKD3_k127_6458747_35 - - - - 0.0000000000009271 69.0
HKD3_k127_6458747_36 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0006487 51.0
HKD3_k127_6458747_4 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.111e-241 758.0
HKD3_k127_6458747_5 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.057e-223 712.0
HKD3_k127_6458747_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 560.0
HKD3_k127_6458747_7 Strictosidine synthase K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 538.0
HKD3_k127_6458747_8 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 507.0
HKD3_k127_6458747_9 NADP-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 481.0
HKD3_k127_6470471_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 1.631e-231 731.0
HKD3_k127_6470471_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 446.0
HKD3_k127_6470471_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
HKD3_k127_6470471_3 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000000000000000000000000007492 207.0
HKD3_k127_6470471_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000003762 169.0
HKD3_k127_6470471_5 NACHT domain K13730 - - 0.0000000000000000000000000000000000000000004132 171.0
HKD3_k127_6470471_6 - - - - 0.0000000000000001199 92.0
HKD3_k127_6478931_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 8.73e-259 814.0
HKD3_k127_6478931_1 TonB dependent receptor - - - 5.312e-214 686.0
HKD3_k127_6478931_2 Formyl transferase K19640 - - 9.032e-213 681.0
HKD3_k127_6478931_3 Belongs to the HypD family K04654 - - 9.454e-196 620.0
HKD3_k127_6478931_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 525.0
HKD3_k127_6478931_5 High-affinity nickel-transport protein K07241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 354.0
HKD3_k127_6478931_6 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000004157 211.0
HKD3_k127_6478931_7 - - - - 0.00000000000000000000000001782 113.0
HKD3_k127_6478931_8 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000006073 107.0
HKD3_k127_6507216_0 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 372.0
HKD3_k127_6510532_0 Ammonium Transporter K03320 - - 2.166e-195 615.0
HKD3_k127_6510532_1 Beta-lactamase K01286 - 3.4.16.4 0.000000004934 63.0
HKD3_k127_6564756_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002177 294.0
HKD3_k127_6564756_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000004827 130.0
HKD3_k127_6579202_0 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 433.0
HKD3_k127_6579202_1 in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 432.0
HKD3_k127_6579202_10 - - - - 0.000000000000005108 87.0
HKD3_k127_6579202_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 301.0
HKD3_k127_6579202_3 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 301.0
HKD3_k127_6579202_4 Protein of unknown function (DUF2938) - - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HKD3_k127_6579202_5 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000003431 205.0
HKD3_k127_6579202_6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000005597 170.0
HKD3_k127_6579202_7 - - - - 0.0000000000000000000000000009785 116.0
HKD3_k127_6579202_8 Cytochrome c K17223 - - 0.00000000000000000000005518 103.0
HKD3_k127_6618556_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1296.0
HKD3_k127_6618556_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1148.0
HKD3_k127_6618556_10 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006037 275.0
HKD3_k127_6618556_11 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000471 238.0
HKD3_k127_6618556_12 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005439 228.0
HKD3_k127_6618556_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000001461 226.0
HKD3_k127_6618556_14 Smr protein MutS2 - - - 0.000000000000000000000000000000000000000000000000000000003433 220.0
HKD3_k127_6618556_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001279 184.0
HKD3_k127_6618556_16 Histidine kinase - - - 0.00000000000000000000003211 116.0
HKD3_k127_6618556_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.517e-295 946.0
HKD3_k127_6618556_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.313e-239 744.0
HKD3_k127_6618556_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.62e-210 659.0
HKD3_k127_6618556_5 protein involved in propionate catabolism - - - 2.624e-206 653.0
HKD3_k127_6618556_6 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 599.0
HKD3_k127_6618556_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 528.0
HKD3_k127_6618556_8 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 362.0
HKD3_k127_6618556_9 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001481 286.0
HKD3_k127_6629780_0 Sulfatase K01130 - 3.1.6.1 4.698e-254 810.0
HKD3_k127_6629780_1 PA domain - - - 2.646e-210 664.0
HKD3_k127_6629780_10 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 427.0
HKD3_k127_6629780_11 demethylmenaquinone methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 412.0
HKD3_k127_6629780_12 ABC-type sugar transport systems permease components K02025,K05814,K10118,K17242,K17245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 413.0
HKD3_k127_6629780_13 ABC-type sugar transport system, permease component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 407.0
HKD3_k127_6629780_14 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 408.0
HKD3_k127_6629780_15 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 408.0
HKD3_k127_6629780_16 transport system fused permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
HKD3_k127_6629780_17 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 346.0
HKD3_k127_6629780_18 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 323.0
HKD3_k127_6629780_19 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 300.0
HKD3_k127_6629780_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 9.259e-205 646.0
HKD3_k127_6629780_20 endonuclease exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009341 251.0
HKD3_k127_6629780_21 - - - - 0.000000000000000000000000000000000000000000000000000000000002591 219.0
HKD3_k127_6629780_22 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000198 127.0
HKD3_k127_6629780_23 - - - - 0.00000000000000000000000000002669 127.0
HKD3_k127_6629780_24 TIR domain - - - 0.0000000000000000000000000002768 128.0
HKD3_k127_6629780_3 Amidohydrolase family K01465 - 3.5.2.3 2.553e-196 629.0
HKD3_k127_6629780_4 Type II secretory pathway, component ExeA K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 598.0
HKD3_k127_6629780_5 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 575.0
HKD3_k127_6629780_6 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 528.0
HKD3_k127_6629780_7 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 487.0
HKD3_k127_6629780_8 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 485.0
HKD3_k127_6629780_9 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 453.0
HKD3_k127_6658794_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1383.0
HKD3_k127_6658794_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.563e-245 773.0
HKD3_k127_6658794_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 501.0
HKD3_k127_6658794_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 512.0
HKD3_k127_6658794_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 422.0
HKD3_k127_6658794_13 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 434.0
HKD3_k127_6658794_14 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 400.0
HKD3_k127_6658794_15 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 385.0
HKD3_k127_6658794_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 392.0
HKD3_k127_6658794_17 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 365.0
HKD3_k127_6658794_18 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 373.0
HKD3_k127_6658794_19 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 331.0
HKD3_k127_6658794_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 5.837e-239 745.0
HKD3_k127_6658794_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 307.0
HKD3_k127_6658794_21 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
HKD3_k127_6658794_22 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001412 280.0
HKD3_k127_6658794_23 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004721 299.0
HKD3_k127_6658794_24 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001622 271.0
HKD3_k127_6658794_25 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000003374 274.0
HKD3_k127_6658794_26 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000004699 266.0
HKD3_k127_6658794_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000001687 240.0
HKD3_k127_6658794_28 hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004378 234.0
HKD3_k127_6658794_29 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
HKD3_k127_6658794_3 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 6.256e-213 678.0
HKD3_k127_6658794_30 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000001344 221.0
HKD3_k127_6658794_31 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000000009297 224.0
HKD3_k127_6658794_32 FCD - - - 0.000000000000000000000000000000000000000000000000000000000001065 214.0
HKD3_k127_6658794_33 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000000000002903 223.0
HKD3_k127_6658794_34 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000001759 197.0
HKD3_k127_6658794_35 PFAM peptidase S16 lon domain protein K07157 - - 0.000000000000000000000000000000000000000000000000001868 198.0
HKD3_k127_6658794_36 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000002764 184.0
HKD3_k127_6658794_37 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000003802 154.0
HKD3_k127_6658794_38 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000000000000000000000000000003087 148.0
HKD3_k127_6658794_39 AAA domain - - - 0.00000000000000000000000000000000004897 154.0
HKD3_k127_6658794_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 4.145e-195 617.0
HKD3_k127_6658794_40 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000007978 130.0
HKD3_k127_6658794_41 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000001182 135.0
HKD3_k127_6658794_42 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000005379 113.0
HKD3_k127_6658794_43 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000917 114.0
HKD3_k127_6658794_44 Histidine kinase - - - 0.00000000000000000000005886 117.0
HKD3_k127_6658794_45 - - - - 0.00000000000000000001579 98.0
HKD3_k127_6658794_46 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000002561 95.0
HKD3_k127_6658794_47 Diguanylate cyclase with PAS PAC sensor - - - 0.0000000000008623 83.0
HKD3_k127_6658794_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 588.0
HKD3_k127_6658794_6 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 576.0
HKD3_k127_6658794_7 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 572.0
HKD3_k127_6658794_8 aminopeptidase N K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 576.0
HKD3_k127_6658794_9 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 563.0
HKD3_k127_6667327_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001215 153.0
HKD3_k127_675410_0 Extracellular ligand-binding receptor K01999 - - 3.718e-200 629.0
HKD3_k127_675410_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 617.0
HKD3_k127_675410_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 486.0
HKD3_k127_675410_3 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 481.0
HKD3_k127_675410_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 456.0
HKD3_k127_675410_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 382.0
HKD3_k127_675410_6 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000143 233.0
HKD3_k127_675410_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000009025 135.0
HKD3_k127_6780938_0 Domain of unknown function (DUF3372) - - - 4.409e-261 815.0
HKD3_k127_6802626_0 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 293.0
HKD3_k127_6802626_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 296.0
HKD3_k127_6899130_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.764e-307 953.0
HKD3_k127_6899130_1 Peptidoglycan-binding domain 1 protein - - - 3.848e-279 896.0
HKD3_k127_6899130_10 mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 370.0
HKD3_k127_6899130_11 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 353.0
HKD3_k127_6899130_12 response regulator, receiver K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 304.0
HKD3_k127_6899130_13 Tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008858 261.0
HKD3_k127_6899130_14 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000904 252.0
HKD3_k127_6899130_15 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000005518 252.0
HKD3_k127_6899130_16 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000006191 235.0
HKD3_k127_6899130_17 Flagellar regulatory protein FleQ - - - 0.00000000000000000000000000000000000000000000000000000001778 203.0
HKD3_k127_6899130_18 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
HKD3_k127_6899130_19 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000007705 198.0
HKD3_k127_6899130_2 Tripartite tricarboxylate transporter TctA family K07793 - - 2.627e-239 754.0
HKD3_k127_6899130_20 PFAM transposase, IS4 family protein K07481 - - 0.0000000000000000000000000000000000000000002773 166.0
HKD3_k127_6899130_21 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000000000000000125 141.0
HKD3_k127_6899130_22 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000392 109.0
HKD3_k127_6899130_23 Plasmid stability protein K21495 - - 0.0000000000000000002654 89.0
HKD3_k127_6899130_24 ATP citrate lyase citrate-binding - - - 0.00000000000000008255 80.0
HKD3_k127_6899130_25 Leucine-rich repeat (LRR) protein - - - 0.00000000000005647 85.0
HKD3_k127_6899130_26 DNA integration - - - 0.0000003431 52.0
HKD3_k127_6899130_27 Protein of unknown function (DUF2934) - - - 0.000002452 55.0
HKD3_k127_6899130_3 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 481.0
HKD3_k127_6899130_4 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 485.0
HKD3_k127_6899130_5 Histidine kinase K07649 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 481.0
HKD3_k127_6899130_6 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 460.0
HKD3_k127_6899130_7 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009488 490.0
HKD3_k127_6899130_8 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 480.0
HKD3_k127_6899130_9 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 397.0
HKD3_k127_6953943_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 512.0
HKD3_k127_6953943_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 430.0
HKD3_k127_6953943_2 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 448.0
HKD3_k127_6953943_3 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000256 274.0
HKD3_k127_6953943_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000007374 105.0
HKD3_k127_7048565_0 transposase IS66 K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 584.0
HKD3_k127_7048565_1 IS66 Orf2 like protein K07484 - - 0.0000000000000000000000000000000000000000000000000000002475 198.0
HKD3_k127_7048565_2 PFAM transposase IS3 IS911 family protein K07483 - - 0.0000000000000003649 86.0
HKD3_k127_7048565_3 TIGRFAM cysteine desulfurase family protein - - - 0.0000000007791 61.0
HKD3_k127_7048565_4 Hemerythrin-like metal-binding protein K07216 - - 0.00002439 47.0
HKD3_k127_7251927_0 Sulfatase K01130 - 3.1.6.1 0.0 1164.0
HKD3_k127_7251927_1 Phospholipase, patatin family K07001 - - 9.227e-229 718.0
HKD3_k127_7251927_2 Prophage CP4-57 regulatory protein (AlpA) K07733 - - 0.000000000000000000000000001058 119.0
HKD3_k127_7251927_3 TfoX N-terminal domain - - - 0.00000000000000000169 88.0
HKD3_k127_7251927_4 Cobyrinic acid ac-diamide synthase K12055 - - 0.0000001179 53.0
HKD3_k127_7251927_5 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.0000006387 59.0
HKD3_k127_7251927_6 Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle K14211 GO:0001101,GO:0001568,GO:0001666,GO:0001944,GO:0001974,GO:0003007,GO:0003008,GO:0003013,GO:0003151,GO:0003170,GO:0003176,GO:0003179,GO:0003180,GO:0003674,GO:0005198,GO:0005201,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007154,GO:0007275,GO:0007507,GO:0007517,GO:0007519,GO:0007568,GO:0007584,GO:0007585,GO:0008015,GO:0008064,GO:0008150,GO:0008283,GO:0009410,GO:0009605,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009887,GO:0009888,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0014070,GO:0014706,GO:0016043,GO:0022607,GO:0030023,GO:0030029,GO:0030036,GO:0030038,GO:0030198,GO:0030832,GO:0030833,GO:0031012,GO:0031032,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031960,GO:0032271,GO:0032501,GO:0032502,GO:0032526,GO:0032535,GO:0032870,GO:0032956,GO:0032970,GO:0033043,GO:0033273,GO:0033554,GO:0033591,GO:0033993,GO:0034284,GO:0035690,GO:0035904,GO:0036293,GO:0036294,GO:0036296,GO:0042221,GO:0042493,GO:0043062,GO:0043149,GO:0043254,GO:0044085,GO:0044087,GO:0044344,GO:0044420,GO:0044421,GO:0046688,GO:0048251,GO:0048513,GO:0048545,GO:0048731,GO:0048771,GO:0048856,GO:0050789,GO:0050794,GO:0050840,GO:0050896,GO:0051017,GO:0051128,GO:0051384,GO:0051493,GO:0051716,GO:0055093,GO:0060537,GO:0060538,GO:0060840,GO:0061061,GO:0061572,GO:0065007,GO:0065008,GO:0070482,GO:0070848,GO:0070887,GO:0071229,GO:0071241,GO:0071248,GO:0071280,GO:0071295,GO:0071298,GO:0071300,GO:0071310,GO:0071322,GO:0071326,GO:0071363,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071453,GO:0071456,GO:0071466,GO:0071495,GO:0071496,GO:0071548,GO:0071549,GO:0071559,GO:0071560,GO:0071774,GO:0071840,GO:0071953,GO:0072358,GO:0072359,GO:0085029,GO:0090066,GO:0097327,GO:0097435,GO:0097493,GO:0110053,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902903,GO:1905314 - 0.00008779 49.0
HKD3_k127_7256326_0 Aldo keto - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 248.0
HKD3_k127_7256326_1 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000005402 152.0
HKD3_k127_7256326_2 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000001848 146.0
HKD3_k127_7285861_0 PFAM Glycosyl transferase, family 2 - - - 0.0 1122.0
HKD3_k127_7285861_1 PFAM Type II secretion system protein E K02454,K02652,K12276 - - 3.058e-241 758.0
HKD3_k127_7285861_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 468.0
HKD3_k127_7285861_11 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 447.0
HKD3_k127_7285861_12 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 448.0
HKD3_k127_7285861_13 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 428.0
HKD3_k127_7285861_14 Phosphomethylpyrimidine kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 409.0
HKD3_k127_7285861_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 385.0
HKD3_k127_7285861_16 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 384.0
HKD3_k127_7285861_17 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 344.0
HKD3_k127_7285861_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 347.0
HKD3_k127_7285861_19 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 348.0
HKD3_k127_7285861_2 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.007e-206 661.0
HKD3_k127_7285861_20 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
HKD3_k127_7285861_21 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 319.0
HKD3_k127_7285861_22 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 307.0
HKD3_k127_7285861_23 Transport permease protein K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 297.0
HKD3_k127_7285861_24 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.00000000000000000000000000000000000000000000000000000000000000000000000000003079 264.0
HKD3_k127_7285861_25 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 263.0
HKD3_k127_7285861_26 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001562 255.0
HKD3_k127_7285861_27 PFAM Fimbrial assembly family protein K02461 - - 0.000000000000000000000000000000000000000000000000000000000000000000007887 246.0
HKD3_k127_7285861_28 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000285 235.0
HKD3_k127_7285861_29 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000008423 235.0
HKD3_k127_7285861_3 PFAM type II and III secretion system protein K02453 - - 8.288e-196 639.0
HKD3_k127_7285861_30 Kdo2-lipid A biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000001596 229.0
HKD3_k127_7285861_31 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HKD3_k127_7285861_32 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000009139 203.0
HKD3_k127_7285861_33 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000003774 207.0
HKD3_k127_7285861_34 PFAM type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000001506 197.0
HKD3_k127_7285861_35 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000001775 203.0
HKD3_k127_7285861_36 type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000000000003843 209.0
HKD3_k127_7285861_37 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000448 196.0
HKD3_k127_7285861_38 methyltransferase - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001299 192.0
HKD3_k127_7285861_39 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000142 189.0
HKD3_k127_7285861_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 553.0
HKD3_k127_7285861_40 TIGRFAM general secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000006161 153.0
HKD3_k127_7285861_41 Pfam:N_methyl_2 K02459 - - 0.000000000000000000000000000000004289 141.0
HKD3_k127_7285861_42 - - - - 0.000000000000000000000000000001125 126.0
HKD3_k127_7285861_43 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000003174 118.0
HKD3_k127_7285861_44 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000001963 125.0
HKD3_k127_7285861_45 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000000000000000000001967 119.0
HKD3_k127_7285861_46 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000003285 96.0
HKD3_k127_7285861_47 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source K10778 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 0.0000000000000167 75.0
HKD3_k127_7285861_48 - - - - 0.0000000009891 71.0
HKD3_k127_7285861_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 547.0
HKD3_k127_7285861_6 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 537.0
HKD3_k127_7285861_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 515.0
HKD3_k127_7285861_8 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 492.0
HKD3_k127_7285861_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 471.0
HKD3_k127_7316118_0 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 298.0
HKD3_k127_7316118_1 High-affinity nickel-transport protein K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009898 246.0
HKD3_k127_7316118_2 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000002416 63.0
HKD3_k127_731761_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 473.0
HKD3_k127_731761_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000129 153.0
HKD3_k127_731761_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002081 152.0
HKD3_k127_731761_3 membrane - - - 0.00000000000000000000000000000005607 133.0
HKD3_k127_731761_4 - - - - 0.0000000000147 73.0
HKD3_k127_7338752_0 Protein of unknown function (DUF533) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 332.0
HKD3_k127_7338752_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.000000000000000000000000000000000001293 147.0
HKD3_k127_7339962_0 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 401.0
HKD3_k127_7339962_1 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 287.0
HKD3_k127_7339962_2 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000127 226.0
HKD3_k127_7339962_3 response regulator - - - 0.0000000000000000000000000000000000000001854 156.0
HKD3_k127_7339962_4 Esterase, PHB depolymerase family - - - 0.000000000000000000000000000000000000005023 158.0
HKD3_k127_7339962_5 - - - - 0.00001876 55.0
HKD3_k127_7351171_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1001.0
HKD3_k127_7351171_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.748e-317 983.0
HKD3_k127_7351171_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 401.0
HKD3_k127_7351171_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
HKD3_k127_7351171_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 346.0
HKD3_k127_7351171_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 320.0
HKD3_k127_7351171_14 Ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
HKD3_k127_7351171_15 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 312.0
HKD3_k127_7351171_16 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002106 280.0
HKD3_k127_7351171_17 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000009538 223.0
HKD3_k127_7351171_18 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000408 203.0
HKD3_k127_7351171_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000003666 179.0
HKD3_k127_7351171_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.951e-309 995.0
HKD3_k127_7351171_20 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000001587 168.0
HKD3_k127_7351171_21 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000003319 161.0
HKD3_k127_7351171_22 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000001182 146.0
HKD3_k127_7351171_23 ATP synthase I chain K02116 - - 0.0000000000000000000000006636 108.0
HKD3_k127_7351171_24 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000002355 111.0
HKD3_k127_7351171_25 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000007836 102.0
HKD3_k127_7351171_26 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000001424 110.0
HKD3_k127_7351171_27 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000003281 76.0
HKD3_k127_7351171_28 - - - - 0.00000001167 64.0
HKD3_k127_7351171_29 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00003487 52.0
HKD3_k127_7351171_3 carboxylic ester hydrolase activity - - - 6.712e-243 771.0
HKD3_k127_7351171_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.062e-200 646.0
HKD3_k127_7351171_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 609.0
HKD3_k127_7351171_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 544.0
HKD3_k127_7351171_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 499.0
HKD3_k127_7351171_8 alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 499.0
HKD3_k127_7351171_9 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 414.0
HKD3_k127_73513_0 Benzoate-CoA ligase family K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 362.0
HKD3_k127_73513_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 356.0
HKD3_k127_7367366_0 4Fe-4S dicluster domain - - - 0.0 1331.0
HKD3_k127_7367366_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 7.521e-218 682.0
HKD3_k127_7367366_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 440.0
HKD3_k127_7367366_11 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 435.0
HKD3_k127_7367366_12 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 404.0
HKD3_k127_7367366_13 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
HKD3_k127_7367366_14 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 407.0
HKD3_k127_7367366_15 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 336.0
HKD3_k127_7367366_16 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 344.0
HKD3_k127_7367366_17 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
HKD3_k127_7367366_18 lipase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
HKD3_k127_7367366_19 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001461 268.0
HKD3_k127_7367366_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.04e-212 675.0
HKD3_k127_7367366_20 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002449 273.0
HKD3_k127_7367366_21 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002996 271.0
HKD3_k127_7367366_22 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
HKD3_k127_7367366_23 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000004415 182.0
HKD3_k127_7367366_24 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000242 164.0
HKD3_k127_7367366_25 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000009489 150.0
HKD3_k127_7367366_26 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000002534 139.0
HKD3_k127_7367366_27 PFAM GYD family protein - - - 0.0000000000000000000000000000000003189 133.0
HKD3_k127_7367366_28 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000004354 134.0
HKD3_k127_7367366_29 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000001118 112.0
HKD3_k127_7367366_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 4.993e-211 695.0
HKD3_k127_7367366_30 - - - - 0.0000000000000000002564 101.0
HKD3_k127_7367366_31 PFAM CBS domain containing protein - - - 0.0000000000000000009794 96.0
HKD3_k127_7367366_32 von Willebrand factor (vWF) type A domain - - - 0.000000261 53.0
HKD3_k127_7367366_4 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 8.641e-209 656.0
HKD3_k127_7367366_5 CoA-transferase family III K07749 - 2.8.3.16 7.39e-198 628.0
HKD3_k127_7367366_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 533.0
HKD3_k127_7367366_7 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 518.0
HKD3_k127_7367366_8 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 492.0
HKD3_k127_7367366_9 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 494.0
HKD3_k127_7392820_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001455 231.0
HKD3_k127_7392820_1 PFAM Hemolysin-type calcium-binding K01406 - 3.4.24.40 0.0000000000000000000000000000001031 139.0
HKD3_k127_7392820_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000009449 80.0
HKD3_k127_7445189_0 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000189 286.0
HKD3_k127_7445189_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000008155 183.0
HKD3_k127_7445189_2 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000007905 129.0
HKD3_k127_7447631_0 Sulfatase - - - 2.601e-207 653.0
HKD3_k127_7447631_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000002754 181.0
HKD3_k127_7463294_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 526.0
HKD3_k127_7463294_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 345.0
HKD3_k127_7463294_2 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000003528 190.0
HKD3_k127_7463294_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000002905 181.0
HKD3_k127_7463294_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000031 168.0
HKD3_k127_7463294_5 - - - - 0.0000000000000008973 82.0
HKD3_k127_7463294_6 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000008142 63.0
HKD3_k127_7464393_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 571.0
HKD3_k127_7464393_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 543.0
HKD3_k127_7464393_2 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000008953 220.0
HKD3_k127_7464393_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000004089 198.0
HKD3_k127_7464393_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000005661 99.0
HKD3_k127_7464393_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00000000001137 71.0
HKD3_k127_7464393_6 - - - - 0.000000001763 64.0
HKD3_k127_74786_0 Histidine kinase-like ATPases - - - 0.0 1385.0
HKD3_k127_74786_1 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1255.0
HKD3_k127_74786_10 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 439.0
HKD3_k127_74786_11 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 417.0
HKD3_k127_74786_12 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 428.0
HKD3_k127_74786_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 409.0
HKD3_k127_74786_14 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 362.0
HKD3_k127_74786_15 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 361.0
HKD3_k127_74786_16 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 349.0
HKD3_k127_74786_17 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 342.0
HKD3_k127_74786_18 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 328.0
HKD3_k127_74786_19 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 320.0
HKD3_k127_74786_2 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1249.0
HKD3_k127_74786_20 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 301.0
HKD3_k127_74786_21 LytTr DNA-binding domain K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 287.0
HKD3_k127_74786_22 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002345 260.0
HKD3_k127_74786_23 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003181 245.0
HKD3_k127_74786_24 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000001452 263.0
HKD3_k127_74786_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HKD3_k127_74786_26 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000001775 233.0
HKD3_k127_74786_27 - - - - 0.000000000000000000000000000000000000000000000000000000001761 207.0
HKD3_k127_74786_28 protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000000000007237 197.0
HKD3_k127_74786_29 Domain of unknown function (DUF4214) - - - 0.0000000000000000000000000000000000000000000000000000166 201.0
HKD3_k127_74786_3 PQQ enzyme repeat - - - 1.725e-299 926.0
HKD3_k127_74786_30 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000968 190.0
HKD3_k127_74786_31 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000000007027 186.0
HKD3_k127_74786_32 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000002061 170.0
HKD3_k127_74786_33 Sel1-like repeats. - - - 0.0000000000000000001623 98.0
HKD3_k127_74786_34 Histidine kinase K20976 - - 0.000000000000000265 83.0
HKD3_k127_74786_35 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000005388 85.0
HKD3_k127_74786_4 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 6.18e-292 923.0
HKD3_k127_74786_5 argininosuccinate lyase K01755 - 4.3.2.1 1.235e-201 662.0
HKD3_k127_74786_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 628.0
HKD3_k127_74786_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 576.0
HKD3_k127_74786_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 547.0
HKD3_k127_74786_9 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 445.0
HKD3_k127_7501662_0 Protein of unknown function (DUF533) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 340.0
HKD3_k127_7501662_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000006983 237.0
HKD3_k127_7501662_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000001084 207.0
HKD3_k127_7501662_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000001602 96.0
HKD3_k127_7501662_4 polyketide synthase - - - 0.0009232 49.0
HKD3_k127_7504678_0 ABC transporter transmembrane region K06147 - - 4.961e-254 798.0
HKD3_k127_7504678_1 Protein of unknown function (DUF808) K09781 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 394.0
HKD3_k127_7504678_10 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000002651 182.0
HKD3_k127_7504678_11 - - - - 0.0000000000000000000000000000000000000000000025 172.0
HKD3_k127_7504678_12 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.000000000000000000001058 95.0
HKD3_k127_7504678_13 - - - - 0.00000000000000001702 89.0
HKD3_k127_7504678_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 394.0
HKD3_k127_7504678_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 343.0
HKD3_k127_7504678_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 322.0
HKD3_k127_7504678_5 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 315.0
HKD3_k127_7504678_6 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
HKD3_k127_7504678_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007017 280.0
HKD3_k127_7504678_8 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000006274 206.0
HKD3_k127_7504678_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000003116 186.0
HKD3_k127_7505175_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 547.0
HKD3_k127_7505175_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 444.0
HKD3_k127_7505175_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 340.0
HKD3_k127_7505175_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000007006 145.0
HKD3_k127_7528371_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1293.0
HKD3_k127_7528371_1 Sulfatase - - - 1.271e-291 900.0
HKD3_k127_7528371_2 Sulfatase K01130 - 3.1.6.1 2.55e-214 676.0
HKD3_k127_7528371_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 578.0
HKD3_k127_7528371_4 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 552.0
HKD3_k127_7528371_5 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 441.0
HKD3_k127_7528371_6 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000000000000000002246 192.0
HKD3_k127_7528371_7 Protein of unknown function (DUF1622) - - - 0.00000000000000000000001288 106.0
HKD3_k127_7528371_8 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000000000000000001398 112.0
HKD3_k127_7528371_9 ABC-2 family transporter protein - - - 0.00000000000000106 76.0
HKD3_k127_7529849_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1527.0
HKD3_k127_7529849_1 arylsulfatase A K01130 - 3.1.6.1 4.573e-279 864.0
HKD3_k127_7529849_10 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 419.0
HKD3_k127_7529849_11 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 421.0
HKD3_k127_7529849_12 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 415.0
HKD3_k127_7529849_13 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 386.0
HKD3_k127_7529849_14 Domain of unknown function (DUF4040) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 369.0
HKD3_k127_7529849_15 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 331.0
HKD3_k127_7529849_16 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 316.0
HKD3_k127_7529849_17 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
HKD3_k127_7529849_18 Domain of unknown function (DUF1794) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 276.0
HKD3_k127_7529849_19 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002022 261.0
HKD3_k127_7529849_2 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 4.447e-251 789.0
HKD3_k127_7529849_20 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
HKD3_k127_7529849_21 Na+/H+ ion antiporter subunit - - - 0.00000000000000000000000000000000000000000000002365 178.0
HKD3_k127_7529849_22 - - - - 0.00000000000000000000000000000000000000000000212 171.0
HKD3_k127_7529849_23 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000001072 157.0
HKD3_k127_7529849_24 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000007238 127.0
HKD3_k127_7529849_25 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000003196 118.0
HKD3_k127_7529849_26 cheY-homologous receiver domain - - - 0.0000000000000000000000211 106.0
HKD3_k127_7529849_27 amino acid K03758 - - 0.00000000000000000000444 98.0
HKD3_k127_7529849_28 Protein of unknown function (DUF1254) - - - 0.00000000000000001718 85.0
HKD3_k127_7529849_29 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000002376 66.0
HKD3_k127_7529849_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.059e-225 739.0
HKD3_k127_7529849_4 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 577.0
HKD3_k127_7529849_5 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 542.0
HKD3_k127_7529849_6 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 531.0
HKD3_k127_7529849_7 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 538.0
HKD3_k127_7529849_8 SMART ATP-binding region, ATPase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 502.0
HKD3_k127_7529849_9 Transposase IS116/IS110/IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 432.0
HKD3_k127_7529895_0 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 377.0
HKD3_k127_7529895_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 366.0
HKD3_k127_7529895_2 integral membrane protein - - - 0.000000000000000000000000000000000002375 142.0
HKD3_k127_7529895_3 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000002486 56.0
HKD3_k127_7545995_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 3.008e-268 838.0
HKD3_k127_7545995_1 Acyl-CoA synthetase (NDP forming) K09181 - - 2.289e-253 810.0
HKD3_k127_7545995_10 hydrogenase maturation protease - - - 0.000000000000000000000000000000001397 149.0
HKD3_k127_7545995_11 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000007187 125.0
HKD3_k127_7545995_12 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000001445 121.0
HKD3_k127_7545995_13 TraB family K09973 - - 0.00000000000000000000000006033 126.0
HKD3_k127_7545995_14 dksA traR - - - 0.000000000000001657 81.0
HKD3_k127_7545995_15 Metal-sensitive transcriptional repressor - - - 0.000000000000001702 84.0
HKD3_k127_7545995_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 5.322e-238 756.0
HKD3_k127_7545995_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 433.0
HKD3_k127_7545995_4 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 366.0
HKD3_k127_7545995_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 329.0
HKD3_k127_7545995_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000002789 268.0
HKD3_k127_7545995_7 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000005649 243.0
HKD3_k127_7545995_8 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000003357 220.0
HKD3_k127_7545995_9 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000734 219.0
HKD3_k127_7611265_0 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
HKD3_k127_7611265_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 340.0
HKD3_k127_7611265_2 FCD - - - 0.000000000000000000000000000001144 124.0
HKD3_k127_765276_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1124.0
HKD3_k127_765276_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.5e-323 1000.0
HKD3_k127_765276_10 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HKD3_k127_765276_11 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000002603 252.0
HKD3_k127_765276_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000001517 241.0
HKD3_k127_765276_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000001049 209.0
HKD3_k127_765276_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000004432 151.0
HKD3_k127_765276_16 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000007409 143.0
HKD3_k127_765276_17 TM2 domain - - - 0.000000000000000000000107 104.0
HKD3_k127_765276_18 Putative prokaryotic signal transducing protein - - - 0.00000000000000000003237 104.0
HKD3_k127_765276_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 532.0
HKD3_k127_765276_3 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 508.0
HKD3_k127_765276_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 484.0
HKD3_k127_765276_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 469.0
HKD3_k127_765276_6 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 314.0
HKD3_k127_765276_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001764 282.0
HKD3_k127_765276_8 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005597 266.0
HKD3_k127_765276_9 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002263 254.0
HKD3_k127_7661104_0 Glucodextranase, domain N K01178 - 3.2.1.3 1.93e-322 1003.0
HKD3_k127_7661104_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 563.0
HKD3_k127_7661104_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000002835 181.0
HKD3_k127_7661104_3 6-phosphogluconolactonase activity K00036,K01057,K13937 GO:0000166,GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0003824,GO:0004345,GO:0005488,GO:0005515,GO:0005536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006066,GO:0006081,GO:0006098,GO:0006139,GO:0006518,GO:0006575,GO:0006629,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006749,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009051,GO:0009058,GO:0009117,GO:0009892,GO:0009898,GO:0009987,GO:0010605,GO:0010732,GO:0010734,GO:0016020,GO:0016051,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016788,GO:0017057,GO:0019222,GO:0019321,GO:0019322,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0021700,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030246,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033554,GO:0034101,GO:0034599,GO:0034641,GO:0036094,GO:0042221,GO:0042592,GO:0042802,GO:0042803,GO:0043249,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046165,GO:0046364,GO:0046390,GO:0046483,GO:0046496,GO:0046983,GO:0048029,GO:0048037,GO:0048468,GO:0048469,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051172,GO:0051186,GO:0051246,GO:0051248,GO:0051716,GO:0052689,GO:0055086,GO:0055114,GO:0060255,GO:0061515,GO:0065007,GO:0065008,GO:0070887,GO:0071695,GO:0071704,GO:0071944,GO:0072524,GO:0080090,GO:0090407,GO:0097159,GO:0098552,GO:0098562,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 1.1.1.363,1.1.1.47,1.1.1.49,3.1.1.31 0.0000000000007626 74.0
HKD3_k127_770441_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 293.0
HKD3_k127_770441_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000008521 121.0
HKD3_k127_7796849_0 Glycosyltransferase WbsX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 420.0
HKD3_k127_7796849_1 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000003632 202.0
HKD3_k127_7796849_2 Methyltransferase domain - - - 0.0000000000000000000000000000000007219 141.0
HKD3_k127_7796849_3 Glycosyltransferase like family - - - 0.0000000000000000000000000000001465 124.0
HKD3_k127_7796849_4 repeat-containing protein - - - 0.00000005412 65.0
HKD3_k127_7796849_5 Glycosyltransferase like family 2 - - - 0.000000135 65.0
HKD3_k127_7796849_6 Glycosyltransferase like family 2 K12987,K12988 - - 0.0009404 51.0
HKD3_k127_7915367_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 370.0
HKD3_k127_7915367_1 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000001118 180.0
HKD3_k127_7915367_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000003889 88.0
HKD3_k127_7931480_0 permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 277.0
HKD3_k127_7931480_1 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
HKD3_k127_7971959_0 Molecular chaperone. Has ATPase activity K04079 - - 1.464e-297 929.0
HKD3_k127_7971959_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 327.0
HKD3_k127_7971959_10 Nuclease-related domain - - - 0.0000000001097 71.0
HKD3_k127_7971959_2 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000004449 257.0
HKD3_k127_7971959_3 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000008827 209.0
HKD3_k127_7971959_4 VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000000000000003323 176.0
HKD3_k127_7971959_5 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000015 189.0
HKD3_k127_7971959_6 Type III restriction enzyme, res subunit - - - 0.000000000000000000000003188 111.0
HKD3_k127_7971959_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000002533 86.0
HKD3_k127_7971959_8 N-6 DNA Methylase - - - 0.00000000000002437 81.0
HKD3_k127_7971959_9 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000007625 72.0
HKD3_k127_7987227_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 602.0
HKD3_k127_7987227_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 571.0
HKD3_k127_7987227_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 397.0
HKD3_k127_7987227_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 365.0
HKD3_k127_7987227_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 341.0
HKD3_k127_7987227_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 337.0
HKD3_k127_7987227_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 329.0
HKD3_k127_7987227_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 305.0
HKD3_k127_7987227_8 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000008367 119.0
HKD3_k127_8033935_0 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 536.0
HKD3_k127_8033935_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 501.0
HKD3_k127_8033935_2 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 308.0
HKD3_k127_8033935_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 304.0
HKD3_k127_8033935_4 Lysine exporter protein (Lyse ygga) K11250 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 286.0
HKD3_k127_8033935_5 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000001313 132.0
HKD3_k127_8041406_0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 483.0
HKD3_k127_8041406_1 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 317.0
HKD3_k127_8041406_2 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000004049 143.0
HKD3_k127_81097_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 488.0
HKD3_k127_81097_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 454.0
HKD3_k127_81097_10 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000005524 160.0
HKD3_k127_81097_11 TPM domain K08988 - - 0.00000000000000000000000000000000000003068 160.0
HKD3_k127_81097_12 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000007225 143.0
HKD3_k127_81097_13 - - - - 0.000000000000000000000000000000000752 140.0
HKD3_k127_81097_14 Domain of unknown function (DUF1992) - - - 0.0000000000000000000004433 104.0
HKD3_k127_81097_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000159 68.0
HKD3_k127_81097_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 400.0
HKD3_k127_81097_3 benzoate transporter K05782 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 381.0
HKD3_k127_81097_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
HKD3_k127_81097_5 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008597 284.0
HKD3_k127_81097_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001 276.0
HKD3_k127_81097_7 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000003302 244.0
HKD3_k127_81097_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000001788 243.0
HKD3_k127_81097_9 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000002116 175.0
HKD3_k127_8174036_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.428e-221 704.0
HKD3_k127_8174036_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 602.0
HKD3_k127_8174036_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 554.0
HKD3_k127_8174036_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 437.0
HKD3_k127_8174036_4 PFAM Semialdehyde dehydrogenase NAD - binding K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
HKD3_k127_8174036_5 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000008016 218.0
HKD3_k127_8174036_6 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000434 198.0
HKD3_k127_8174036_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000000000001969 194.0
HKD3_k127_8174036_8 FAD dependent oxidoreductase central domain K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.00000000000000000000001147 102.0
HKD3_k127_8174036_9 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000003138 50.0
HKD3_k127_817540_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 9.777e-320 1003.0
HKD3_k127_817540_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 1.969e-286 889.0
HKD3_k127_817540_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 376.0
HKD3_k127_817540_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 346.0
HKD3_k127_817540_12 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 342.0
HKD3_k127_817540_13 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 306.0
HKD3_k127_817540_14 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258 - 1.5.1.25,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 310.0
HKD3_k127_817540_15 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
HKD3_k127_817540_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 293.0
HKD3_k127_817540_17 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 299.0
HKD3_k127_817540_18 TOBE domain K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002107 286.0
HKD3_k127_817540_19 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002639 275.0
HKD3_k127_817540_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.381e-263 856.0
HKD3_k127_817540_20 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003211 287.0
HKD3_k127_817540_21 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007842 257.0
HKD3_k127_817540_22 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
HKD3_k127_817540_23 Branched-chain amino acid permease - - - 0.000000000000000000000000000000000000000000000000000003712 214.0
HKD3_k127_817540_24 cytochrome - - - 0.000000000000000000000000000000000000000000000001072 180.0
HKD3_k127_817540_25 - - - - 0.000000000000000000000000000000000000000000000005991 179.0
HKD3_k127_817540_26 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000004225 142.0
HKD3_k127_817540_27 SnoaL-like domain - - - 0.00000000000000000000000000000001056 132.0
HKD3_k127_817540_28 PFAM cytochrome c - - - 0.00000000000000000000000001778 115.0
HKD3_k127_817540_29 Zinc-finger domain - - - 0.0000000000000000001267 101.0
HKD3_k127_817540_3 peptidase U62, modulator of DNA gyrase K03568 - - 3.164e-211 671.0
HKD3_k127_817540_30 Pfam Branched-chain amino acid transport - - - 0.0000000000000000004443 100.0
HKD3_k127_817540_31 - - - - 0.0000000000008066 81.0
HKD3_k127_817540_4 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 602.0
HKD3_k127_817540_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 593.0
HKD3_k127_817540_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 505.0
HKD3_k127_817540_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 427.0
HKD3_k127_817540_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 422.0
HKD3_k127_817540_9 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 387.0
HKD3_k127_8254954_0 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 507.0
HKD3_k127_8254954_1 PFAM dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 335.0
HKD3_k127_8254954_2 PFAM Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 284.0
HKD3_k127_8277160_0 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 368.0
HKD3_k127_8277160_1 pilus organization K07346 - - 0.00000000000000000000000000000000000000008212 160.0
HKD3_k127_8402920_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 7.744e-316 968.0
HKD3_k127_8402920_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.222e-272 849.0
HKD3_k127_8402920_10 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 449.0
HKD3_k127_8402920_11 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 431.0
HKD3_k127_8402920_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 426.0
HKD3_k127_8402920_13 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 363.0
HKD3_k127_8402920_14 PFAM peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 367.0
HKD3_k127_8402920_15 Nitrate reductase K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 344.0
HKD3_k127_8402920_16 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 341.0
HKD3_k127_8402920_17 NnrS protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 317.0
HKD3_k127_8402920_18 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 319.0
HKD3_k127_8402920_19 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 325.0
HKD3_k127_8402920_2 Bacterial protein of unknown function (DUF853) K06915 - - 3.207e-234 737.0
HKD3_k127_8402920_20 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 294.0
HKD3_k127_8402920_21 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006331 282.0
HKD3_k127_8402920_22 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000646 273.0
HKD3_k127_8402920_23 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD3_k127_8402920_24 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000002041 231.0
HKD3_k127_8402920_25 Transcriptional regulator K13771 - - 0.00000000000000000000000000000000000000000000000001064 190.0
HKD3_k127_8402920_26 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000004714 184.0
HKD3_k127_8402920_27 - - - - 0.0000000000000000000000000000000000000000000001014 172.0
HKD3_k127_8402920_28 DGC domain - - - 0.00000000000000000000000000000000000000000001239 167.0
HKD3_k127_8402920_29 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000003209 166.0
HKD3_k127_8402920_3 Cytochrome b(N-terminal)/b6/petB - - - 3.193e-228 722.0
HKD3_k127_8402920_30 - - - - 0.00000000000000000000000000000000000000006259 158.0
HKD3_k127_8402920_31 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000003244 147.0
HKD3_k127_8402920_32 Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000004077 145.0
HKD3_k127_8402920_33 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000005549 155.0
HKD3_k127_8402920_34 - - - - 0.00000000000000000000000000000008463 129.0
HKD3_k127_8402920_35 - - - - 0.0000000000000000000000000000002385 128.0
HKD3_k127_8402920_36 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000001138 123.0
HKD3_k127_8402920_37 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000003539 121.0
HKD3_k127_8402920_38 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000027 97.0
HKD3_k127_8402920_39 - - - - 0.000000000002945 68.0
HKD3_k127_8402920_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 9.736e-208 656.0
HKD3_k127_8402920_40 Uncharacterized conserved protein (DUF2249) - - - 0.000000001163 70.0
HKD3_k127_8402920_5 Belongs to the GARS family K01945 - 6.3.4.13 1.695e-196 621.0
HKD3_k127_8402920_6 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 535.0
HKD3_k127_8402920_7 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 510.0
HKD3_k127_8402920_8 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 510.0
HKD3_k127_8402920_9 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 488.0
HKD3_k127_8461314_0 PFAM extracellular solute-binding protein family 5 K12368 - - 1.48e-294 929.0
HKD3_k127_8461314_1 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 559.0
HKD3_k127_8461314_10 Cytochrome c - - - 0.0000000000000000009066 99.0
HKD3_k127_8461314_11 COG2863 Cytochrome c553 - - - 0.0000000006164 68.0
HKD3_k127_8461314_2 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 514.0
HKD3_k127_8461314_3 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 472.0
HKD3_k127_8461314_4 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 479.0
HKD3_k127_8461314_5 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000001762 225.0
HKD3_k127_8461314_6 - - - - 0.000000000000000000000000000000000000000000000001799 183.0
HKD3_k127_8461314_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000008689 106.0
HKD3_k127_8461314_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000001315 102.0
HKD3_k127_8461314_9 cytochrome K17230 - - 0.0000000000000000005523 100.0
HKD3_k127_8463493_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1048.0
HKD3_k127_8463493_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 6.329e-318 992.0
HKD3_k127_8463493_10 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 391.0
HKD3_k127_8463493_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
HKD3_k127_8463493_12 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 410.0
HKD3_k127_8463493_13 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 362.0
HKD3_k127_8463493_14 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 374.0
HKD3_k127_8463493_15 Vitamin k epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 361.0
HKD3_k127_8463493_16 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 346.0
HKD3_k127_8463493_17 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 331.0
HKD3_k127_8463493_18 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 329.0
HKD3_k127_8463493_19 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 296.0
HKD3_k127_8463493_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 2.749e-312 985.0
HKD3_k127_8463493_20 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002253 285.0
HKD3_k127_8463493_21 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 261.0
HKD3_k127_8463493_22 PFAM Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007706 256.0
HKD3_k127_8463493_23 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001112 265.0
HKD3_k127_8463493_24 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001184 258.0
HKD3_k127_8463493_25 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000002594 243.0
HKD3_k127_8463493_26 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003289 232.0
HKD3_k127_8463493_27 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000006503 223.0
HKD3_k127_8463493_28 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000000000000000000000001574 213.0
HKD3_k127_8463493_29 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000002513 219.0
HKD3_k127_8463493_3 CoA binding domain - - - 2.169e-270 850.0
HKD3_k127_8463493_30 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000008506 200.0
HKD3_k127_8463493_31 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000001055 185.0
HKD3_k127_8463493_32 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000006607 171.0
HKD3_k127_8463493_33 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000003667 168.0
HKD3_k127_8463493_34 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000161 164.0
HKD3_k127_8463493_35 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000154 155.0
HKD3_k127_8463493_36 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000008208 137.0
HKD3_k127_8463493_38 transcriptional regulator - - - 0.0000000000000000000000000000002343 139.0
HKD3_k127_8463493_39 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000001962 119.0
HKD3_k127_8463493_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.475e-247 783.0
HKD3_k127_8463493_40 amine dehydrogenase activity K13730 - - 0.0000000000000000000000000008556 130.0
HKD3_k127_8463493_41 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000001052 109.0
HKD3_k127_8463493_43 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000009014 84.0
HKD3_k127_8463493_5 GMC oxidoreductase K00108 - 1.1.99.1 1.426e-241 758.0
HKD3_k127_8463493_6 Poly-beta-hydroxybutyrate polymerase K03821 - - 4.931e-209 669.0
HKD3_k127_8463493_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 539.0
HKD3_k127_8463493_8 fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 535.0
HKD3_k127_8463493_9 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 397.0
HKD3_k127_8482707_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.867e-249 783.0
HKD3_k127_8482707_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005339 253.0
HKD3_k127_8482707_2 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000003669 133.0
HKD3_k127_8493691_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.058e-203 642.0
HKD3_k127_8493691_1 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
HKD3_k127_8493691_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000003432 226.0
HKD3_k127_8493691_3 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000039 156.0
HKD3_k127_8533214_0 4Fe-4S dicluster domain K18930 - - 0.0 1112.0
HKD3_k127_8533214_1 Malate dehydrogenase K00029 - 1.1.1.40 5.08e-321 1000.0
HKD3_k127_8533214_10 Glycine-zipper domain - - - 0.0000000000000000000000000000000017 146.0
HKD3_k127_8533214_11 - - - - 0.0000000000004999 78.0
HKD3_k127_8533214_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00001745 50.0
HKD3_k127_8533214_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 581.0
HKD3_k127_8533214_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 548.0
HKD3_k127_8533214_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
HKD3_k127_8533214_5 N-acyl-D-aspartate D-glutamate deacylase K06015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 422.0
HKD3_k127_8533214_6 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 398.0
HKD3_k127_8533214_7 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008256 246.0
HKD3_k127_8533214_8 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000351 200.0
HKD3_k127_8533214_9 SEC-C motif domain protein K07039 - - 0.000000000000000000000000000000000000197 153.0
HKD3_k127_8573708_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 6.623e-271 844.0
HKD3_k127_8573708_1 PFAM transposase IS116 IS110 IS902 family protein - - - 1.995e-230 720.0
HKD3_k127_8573708_10 - - - - 0.000004097 57.0
HKD3_k127_8573708_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 2.241e-207 676.0
HKD3_k127_8573708_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 466.0
HKD3_k127_8573708_4 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 415.0
HKD3_k127_8573708_5 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003783 230.0
HKD3_k127_8573708_6 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000002829 149.0
HKD3_k127_8573708_7 FMN binding - - - 0.00000000000000000000000000000004797 132.0
HKD3_k127_8573708_8 AAA domain K07028 - - 0.000000000000000000000000000001327 126.0
HKD3_k127_8576133_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1216.0
HKD3_k127_8576133_1 His Kinase A (phospho-acceptor) domain - - - 0.0 1161.0
HKD3_k127_8576133_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 404.0
HKD3_k127_8576133_11 Zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 426.0
HKD3_k127_8576133_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 398.0
HKD3_k127_8576133_13 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 398.0
HKD3_k127_8576133_14 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 372.0
HKD3_k127_8576133_15 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 375.0
HKD3_k127_8576133_16 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 366.0
HKD3_k127_8576133_17 AbiEi antitoxin C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 343.0
HKD3_k127_8576133_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
HKD3_k127_8576133_19 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 325.0
HKD3_k127_8576133_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.171e-283 877.0
HKD3_k127_8576133_20 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 328.0
HKD3_k127_8576133_21 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 323.0
HKD3_k127_8576133_22 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 285.0
HKD3_k127_8576133_23 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000005814 225.0
HKD3_k127_8576133_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000006707 228.0
HKD3_k127_8576133_25 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000001012 197.0
HKD3_k127_8576133_26 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000001391 208.0
HKD3_k127_8576133_27 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000001693 192.0
HKD3_k127_8576133_28 plasmid maintenance system antidote protein K21498 - - 0.000000000000000000000000000000000000000000000002204 176.0
HKD3_k127_8576133_29 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000000000000007667 164.0
HKD3_k127_8576133_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.744e-280 880.0
HKD3_k127_8576133_30 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000001485 175.0
HKD3_k127_8576133_31 Oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000006556 162.0
HKD3_k127_8576133_32 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000002082 159.0
HKD3_k127_8576133_33 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000002128 151.0
HKD3_k127_8576133_34 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000005346 132.0
HKD3_k127_8576133_35 Domain of unknown function (DUF4124) - - - 0.000000000000000000001651 104.0
HKD3_k127_8576133_36 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000138 87.0
HKD3_k127_8576133_37 PFAM Plasmid maintenance system killer K07334 - - 0.00000000000001758 76.0
HKD3_k127_8576133_38 - - - - 0.0000000005747 64.0
HKD3_k127_8576133_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.557e-242 755.0
HKD3_k127_8576133_5 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 603.0
HKD3_k127_8576133_6 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 466.0
HKD3_k127_8576133_7 PFAM transposase, IS4 family protein K07481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 445.0
HKD3_k127_8576133_8 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 435.0
HKD3_k127_8576133_9 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 427.0
HKD3_k127_8584738_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 7.205e-231 729.0
HKD3_k127_8584738_1 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 308.0
HKD3_k127_8584738_2 Universal stress protein family - - - 0.000000000000000000000000000000000002292 145.0
HKD3_k127_8595082_0 Sodium/hydrogen exchanger family - - - 4.521e-198 625.0
HKD3_k127_8655687_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 388.0
HKD3_k127_8655687_1 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.0000000000000000000000000000000002512 136.0
HKD3_k127_8661306_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 2.518e-284 883.0
HKD3_k127_8661306_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 526.0
HKD3_k127_8661306_2 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 511.0
HKD3_k127_8661306_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000002378 185.0
HKD3_k127_8661306_4 PIN domain - - - 0.000000001343 66.0
HKD3_k127_8661306_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000285 70.0
HKD3_k127_8661632_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1477.0
HKD3_k127_8661632_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 529.0
HKD3_k127_8661632_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 506.0
HKD3_k127_8661632_3 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 325.0
HKD3_k127_8661632_4 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 304.0
HKD3_k127_8661632_5 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000916 267.0
HKD3_k127_8661632_6 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000001333 182.0
HKD3_k127_8661632_7 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.000000000000000000000000000000000000000000302 168.0
HKD3_k127_8661632_8 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000000000437 142.0
HKD3_k127_8661632_9 OmpA family - - - 0.0000000000000000000004154 104.0
HKD3_k127_8681146_0 Acetyl-CoA carboxylase, central region - - - 0.0 1564.0
HKD3_k127_8681146_1 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 1076.0
HKD3_k127_8681146_2 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 469.0
HKD3_k127_8681146_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 400.0
HKD3_k127_8681146_4 PFAM Transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 399.0
HKD3_k127_8681146_5 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000007517 197.0
HKD3_k127_8681146_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000004348 177.0
HKD3_k127_8681146_7 ADP binding - - - 0.00000000000000000000000000000000000000000000232 184.0
HKD3_k127_8681146_8 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000000000000000002837 157.0
HKD3_k127_8681146_9 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000001665 124.0
HKD3_k127_8686405_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
HKD3_k127_8686405_1 oxidoreductase activity - - - 0.00000000002922 67.0
HKD3_k127_8696023_0 Domain of unknown function (DUF3394) - - - 9.259e-287 888.0
HKD3_k127_8696023_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 1.234e-278 867.0
HKD3_k127_8696023_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 576.0
HKD3_k127_8696023_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 372.0
HKD3_k127_8696023_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 340.0
HKD3_k127_8696023_5 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 325.0
HKD3_k127_8702478_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0 1103.0
HKD3_k127_8702478_1 Proton-conducting membrane transporter - - - 1.825e-309 960.0
HKD3_k127_8702478_10 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 541.0
HKD3_k127_8702478_11 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 525.0
HKD3_k127_8702478_12 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 496.0
HKD3_k127_8702478_13 LysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
HKD3_k127_8702478_14 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 475.0
HKD3_k127_8702478_15 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 434.0
HKD3_k127_8702478_16 COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 420.0
HKD3_k127_8702478_17 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 394.0
HKD3_k127_8702478_18 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 394.0
HKD3_k127_8702478_19 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 368.0
HKD3_k127_8702478_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.006e-305 951.0
HKD3_k127_8702478_20 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 346.0
HKD3_k127_8702478_21 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 330.0
HKD3_k127_8702478_22 esterase K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 309.0
HKD3_k127_8702478_23 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003421 288.0
HKD3_k127_8702478_24 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001883 262.0
HKD3_k127_8702478_25 PFAM Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000002207 222.0
HKD3_k127_8702478_26 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000005468 218.0
HKD3_k127_8702478_27 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000004024 194.0
HKD3_k127_8702478_28 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000003549 190.0
HKD3_k127_8702478_29 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000166 188.0
HKD3_k127_8702478_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.777e-234 738.0
HKD3_k127_8702478_30 - - - - 0.00000000000000000000000000000000000000006141 156.0
HKD3_k127_8702478_31 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 - 2.3.1.82 0.000000000000000000000000000000000001701 157.0
HKD3_k127_8702478_32 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000008043 143.0
HKD3_k127_8702478_33 Uroporphyrinogen III synthase HEM4 K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000001116 113.0
HKD3_k127_8702478_34 Domain of unknown function (DUF1330) - - - 0.000000000000000000005453 95.0
HKD3_k127_8702478_35 PFAM CopG domain protein DNA-binding domain protein - - - 0.000000000000000000007624 93.0
HKD3_k127_8702478_36 - - - - 0.0000000000004903 80.0
HKD3_k127_8702478_37 Domain of unknown function (DUF4926) - - - 0.000000000002561 70.0
HKD3_k127_8702478_38 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair - - - 0.0000000008182 64.0
HKD3_k127_8702478_4 Prolyl oligopeptidase family - - - 1.706e-231 744.0
HKD3_k127_8702478_5 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 5.05e-231 724.0
HKD3_k127_8702478_6 transporter, DctM subunit - - - 1.569e-200 632.0
HKD3_k127_8702478_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 591.0
HKD3_k127_8702478_8 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 579.0
HKD3_k127_8702478_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 554.0
HKD3_k127_8726292_0 Domain of unknown function (DUF3479) K03403 - 6.6.1.1 0.0 1752.0
HKD3_k127_8726292_1 histidine kinase A domain protein - - - 1.148e-221 709.0
HKD3_k127_8726292_10 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 401.0
HKD3_k127_8726292_11 PFAM Photosynthetic reaction centre K13991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 311.0
HKD3_k127_8726292_12 Photosynthetic complex assembly protein 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 291.0
HKD3_k127_8726292_13 phosphorelay signal transduction system K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 297.0
HKD3_k127_8726292_14 TIGRFAM magnesium protoporphyrin O-methyltransferase K03428 - 2.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003628 301.0
HKD3_k127_8726292_15 PFAM 2-vinyl bacteriochlorophyllide hydratase K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000000002676 225.0
HKD3_k127_8726292_16 B12-binding - - - 0.0000000000000000000000000000000000000000000000000000000000002732 223.0
HKD3_k127_8726292_17 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000000000000002849 222.0
HKD3_k127_8726292_18 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000002928 205.0
HKD3_k127_8726292_19 Heme oxygenase K21480 - 1.14.15.20 0.000000000000000000000000000000001236 141.0
HKD3_k127_8726292_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 6.733e-199 656.0
HKD3_k127_8726292_20 Photosynthetic complex assembly protein - - - 0.00000000000000000000000000000004593 131.0
HKD3_k127_8726292_21 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08939 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000006239 99.0
HKD3_k127_8726292_22 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08930 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000005249 82.0
HKD3_k127_8726292_23 - - - - 0.000000000001562 70.0
HKD3_k127_8726292_24 - - - - 0.00000006536 62.0
HKD3_k127_8726292_3 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 1.039e-197 632.0
HKD3_k127_8726292_4 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 576.0
HKD3_k127_8726292_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 544.0
HKD3_k127_8726292_6 PFAM PUCC protein K08226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 546.0
HKD3_k127_8726292_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 520.0
HKD3_k127_8726292_8 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 515.0
HKD3_k127_8726292_9 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K04037 - 1.3.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 508.0
HKD3_k127_8752835_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
HKD3_k127_8752835_1 - - - - 0.000000000000000000000000000000000000000000000001295 183.0
HKD3_k127_8752835_2 Cytochrome c - - - 0.00000000000000000000000000000000161 145.0
HKD3_k127_8752835_3 cytochrome - - - 0.000000000000000000000001899 112.0
HKD3_k127_8752835_4 Pfam cytochrome c - - - 0.00000000001745 74.0
HKD3_k127_8752835_5 cytochrome - - - 0.0001242 52.0
HKD3_k127_8764762_0 Benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 9.298e-231 720.0
HKD3_k127_8764762_1 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 2.64e-221 710.0
HKD3_k127_8764762_10 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000004495 271.0
HKD3_k127_8764762_11 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001045 226.0
HKD3_k127_8764762_12 PIN domain - - - 0.00000000000000000000005533 107.0
HKD3_k127_8764762_13 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.0000000002832 65.0
HKD3_k127_8764762_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.837e-215 675.0
HKD3_k127_8764762_3 ABC-type sugar transport system periplasmic component K02027 - - 8.982e-205 645.0
HKD3_k127_8764762_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 555.0
HKD3_k127_8764762_5 TOBE domain K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 530.0
HKD3_k127_8764762_6 Enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 413.0
HKD3_k127_8764762_7 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 385.0
HKD3_k127_8764762_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 397.0
HKD3_k127_8764762_9 PFAM PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 363.0
HKD3_k127_8803996_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1369.0
HKD3_k127_8803996_1 Sodium:sulfate symporter transmembrane region - - - 2.693e-231 730.0
HKD3_k127_8803996_10 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 469.0
HKD3_k127_8803996_11 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 424.0
HKD3_k127_8803996_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 374.0
HKD3_k127_8803996_13 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 378.0
HKD3_k127_8803996_14 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 340.0
HKD3_k127_8803996_15 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
HKD3_k127_8803996_16 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000001445 230.0
HKD3_k127_8803996_17 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.000000000000000000000000000000000000000000000000000000000000365 219.0
HKD3_k127_8803996_18 - - - - 0.000000000000000000000000000000000000000000000000000000000001388 218.0
HKD3_k127_8803996_19 Excalibur calcium-binding domain - - - 0.000000000000000000000000000000000000000000000000007899 186.0
HKD3_k127_8803996_2 COG0471 Di- and tricarboxylate transporters - - - 3.123e-227 719.0
HKD3_k127_8803996_20 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000002007 186.0
HKD3_k127_8803996_21 Nuclease-related domain - - - 0.0000000000000000000000000000000000000000000000000472 180.0
HKD3_k127_8803996_22 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000000000000000000000000000000000001606 173.0
HKD3_k127_8803996_23 Domain of unknown function (DUF4377) - - - 0.00000000000000000000000000000000000000000000006227 180.0
HKD3_k127_8803996_24 - - - - 0.0000000000000000000000000000000000000001593 156.0
HKD3_k127_8803996_25 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000001253 140.0
HKD3_k127_8803996_26 TIR domain - - - 0.000000000000000000000000004506 121.0
HKD3_k127_8803996_27 PFAM plasmid K06218 - - 0.00000000000000000000000001551 110.0
HKD3_k127_8803996_28 - - - - 0.0000000000000000000002234 108.0
HKD3_k127_8803996_29 Protein of unknown function (DUF433) - - - 0.00000000000000000003964 93.0
HKD3_k127_8803996_3 Threonine synthase K01733 - 4.2.3.1 6.361e-205 647.0
HKD3_k127_8803996_30 - - - - 0.000000000000000000108 94.0
HKD3_k127_8803996_31 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000005563 99.0
HKD3_k127_8803996_32 peptidoglycan-binding protein, lysm - - - 0.000000000000000001559 88.0
HKD3_k127_8803996_33 - - - - 0.000000000000000002762 89.0
HKD3_k127_8803996_34 - - - - 0.00000000000004272 76.0
HKD3_k127_8803996_35 type I restriction-modification system K03427 - 2.1.1.72 0.00000000000005313 75.0
HKD3_k127_8803996_36 Mut7-C RNAse domain - - - 0.00000000001981 72.0
HKD3_k127_8803996_4 AbgT putative transporter family K12942 - - 4.586e-201 638.0
HKD3_k127_8803996_5 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
HKD3_k127_8803996_6 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 526.0
HKD3_k127_8803996_7 Mechanosensitive ion channel K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 548.0
HKD3_k127_8803996_8 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 505.0
HKD3_k127_8803996_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 480.0
HKD3_k127_8832441_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000007298 209.0
HKD3_k127_8832441_1 O-antigen ligase like membrane protein - - - 0.00000000000000000004802 97.0
HKD3_k127_8832441_2 transferase activity, transferring glycosyl groups - - - 0.0000000005323 64.0
HKD3_k127_8851743_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 4.161e-224 705.0
HKD3_k127_8851743_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 560.0
HKD3_k127_8851743_2 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002584 278.0
HKD3_k127_8851743_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000001478 168.0
HKD3_k127_8851743_4 - - - - 0.0000000000000002032 90.0
HKD3_k127_8855101_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 580.0
HKD3_k127_8855101_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 488.0
HKD3_k127_8855101_2 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001419 258.0
HKD3_k127_8855101_3 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000001048 122.0
HKD3_k127_8865851_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 338.0
HKD3_k127_8865851_1 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000009002 258.0
HKD3_k127_8865851_2 - - - - 0.00000001739 64.0
HKD3_k127_8866046_0 cytochrome P-450 K21116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 614.0
HKD3_k127_8866046_1 Enoyl-(Acyl carrier protein) reductase K00059,K18609 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0050235,GO:0055114,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.100,1.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 398.0
HKD3_k127_8866046_2 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 306.0
HKD3_k127_8866046_3 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000007073 168.0
HKD3_k127_8866046_4 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000001979 114.0
HKD3_k127_8866046_5 oxidoreductase activity, acting on CH-OH group of donors K16260 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000000002258 71.0
HKD3_k127_8883001_0 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009858 518.0
HKD3_k127_8883001_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000004142 93.0
HKD3_k127_8894388_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.046e-252 790.0
HKD3_k127_8894388_1 NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 518.0
HKD3_k127_8894388_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000021 196.0
HKD3_k127_8894388_11 PFAM metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000008626 208.0
HKD3_k127_8894388_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000002847 174.0
HKD3_k127_8894388_13 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000002525 161.0
HKD3_k127_8894388_14 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000005129 162.0
HKD3_k127_8894388_15 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000000000000006021 98.0
HKD3_k127_8894388_16 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000006659 90.0
HKD3_k127_8894388_17 CAAX amino terminal protease family K07052 - - 0.0000000000002053 79.0
HKD3_k127_8894388_19 Shikimate kinase - - - 0.0004876 49.0
HKD3_k127_8894388_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 505.0
HKD3_k127_8894388_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 478.0
HKD3_k127_8894388_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 456.0
HKD3_k127_8894388_5 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
HKD3_k127_8894388_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 333.0
HKD3_k127_8894388_7 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000688 256.0
HKD3_k127_8894388_8 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003169 252.0
HKD3_k127_8894388_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
HKD3_k127_8908107_0 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000002688 200.0
HKD3_k127_8908107_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000001462 171.0
HKD3_k127_8908107_2 Protein of unknown function (DUF1282) - - - 0.00000000000000000005105 98.0
HKD3_k127_8908107_3 Regulatory protein MarR - - - 0.0000122 48.0
HKD3_k127_8913191_0 chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 2.659e-265 822.0
HKD3_k127_8913191_1 TIGRFAM Chlorophyllide reductase subunit Y K11334 - 1.3.7.14,1.3.7.15 8.588e-260 811.0
HKD3_k127_8913191_10 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 389.0
HKD3_k127_8913191_11 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 406.0
HKD3_k127_8913191_12 PFAM hydroxyneurosporene synthase K09844 - 4.2.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 389.0
HKD3_k127_8913191_13 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 305.0
HKD3_k127_8913191_14 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000401 230.0
HKD3_k127_8913191_15 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000005896 154.0
HKD3_k127_8913191_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000001377 126.0
HKD3_k127_8913191_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000556 107.0
HKD3_k127_8913191_18 Cold shock protein K03704 - - 0.0000000000000000001198 92.0
HKD3_k127_8913191_19 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08926 - - 0.000000000000000004361 85.0
HKD3_k127_8913191_2 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 582.0
HKD3_k127_8913191_20 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001143 79.0
HKD3_k127_8913191_21 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000003257 93.0
HKD3_k127_8913191_22 - K08927 - - 0.000000002779 62.0
HKD3_k127_8913191_3 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 565.0
HKD3_k127_8913191_4 Belongs to the NifH BchL ChlL family K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 572.0
HKD3_k127_8913191_5 Photosynthetic reaction centre protein K08928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 523.0
HKD3_k127_8913191_6 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 500.0
HKD3_k127_8913191_7 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase K11337 - 1.1.1.396 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 464.0
HKD3_k127_8913191_8 Dimerisation domain K09846 - 2.1.1.210 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 422.0
HKD3_k127_8913191_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 393.0
HKD3_k127_8916511_0 Multicopper oxidase K08100 - 1.3.3.5 0.000000000000000000000000000000001909 130.0
HKD3_k127_8916511_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000792 108.0
HKD3_k127_8916511_2 Copper binding periplasmic protein CusF - - - 0.0000000000000000001845 94.0
HKD3_k127_8928446_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 576.0
HKD3_k127_8928446_1 PFAM extracellular solute-binding protein family 1 K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 548.0
HKD3_k127_8928446_10 - - - - 0.000000000000000000000000000000000001276 144.0
HKD3_k127_8928446_11 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000007473 112.0
HKD3_k127_8928446_12 - - - - 0.0000000000000000000002008 99.0
HKD3_k127_8928446_13 - - - - 0.000000000000000000002097 106.0
HKD3_k127_8928446_14 LysR substrate binding domain - - - 0.00000000000000007296 86.0
HKD3_k127_8928446_2 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 448.0
HKD3_k127_8928446_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 393.0
HKD3_k127_8928446_4 binding-protein-dependent transport systems inner membrane component K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 366.0
HKD3_k127_8928446_5 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 364.0
HKD3_k127_8928446_6 (ABC) transporter K02028,K02029 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 344.0
HKD3_k127_8928446_7 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 336.0
HKD3_k127_8928446_8 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 291.0
HKD3_k127_8928446_9 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 293.0
HKD3_k127_8930676_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1241.0
HKD3_k127_8930676_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.779e-316 977.0
HKD3_k127_8930676_10 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 482.0
HKD3_k127_8930676_11 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 454.0
HKD3_k127_8930676_12 Monoamine oxidase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 456.0
HKD3_k127_8930676_13 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 367.0
HKD3_k127_8930676_14 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 346.0
HKD3_k127_8930676_15 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 332.0
HKD3_k127_8930676_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 316.0
HKD3_k127_8930676_17 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 308.0
HKD3_k127_8930676_18 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 310.0
HKD3_k127_8930676_19 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 294.0
HKD3_k127_8930676_2 Domain of Unknown Function (DUF748) - - - 1.175e-233 767.0
HKD3_k127_8930676_20 Short-chain dehydrogenase reductase sdr K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001153 297.0
HKD3_k127_8930676_21 TIGRFAM death-on-curing family protein K07341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009926 245.0
HKD3_k127_8930676_22 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000001579 261.0
HKD3_k127_8930676_23 iron-storage protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000249 230.0
HKD3_k127_8930676_24 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000002417 225.0
HKD3_k127_8930676_25 addiction module killer protein - - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
HKD3_k127_8930676_26 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000001317 210.0
HKD3_k127_8930676_27 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000003523 193.0
HKD3_k127_8930676_28 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000001055 195.0
HKD3_k127_8930676_29 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000002924 187.0
HKD3_k127_8930676_3 Serine dehydratase beta chain K01752 - 4.3.1.17 1.314e-224 703.0
HKD3_k127_8930676_30 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000000000000000000003496 183.0
HKD3_k127_8930676_31 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000000000003415 163.0
HKD3_k127_8930676_32 - - - - 0.00000000000000000000000000000000000005557 143.0
HKD3_k127_8930676_33 - - - - 0.00000000000000000000000000000000000522 154.0
HKD3_k127_8930676_34 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.0000000000000000000000000000000004786 132.0
HKD3_k127_8930676_35 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000007886 128.0
HKD3_k127_8930676_36 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000000004059 122.0
HKD3_k127_8930676_37 Protein of unknown function (DUF3375) - - - 0.000000000000000000000000003313 117.0
HKD3_k127_8930676_38 Tetratricopeptide repeat - - - 0.00000000000000000000000007383 123.0
HKD3_k127_8930676_39 peptidyl-tyrosine sulfation - - - 0.00000000001389 77.0
HKD3_k127_8930676_4 GntP family permease - - - 2.091e-206 651.0
HKD3_k127_8930676_40 COG2906 Bacterioferritin-associated ferredoxin K02192 - - 0.0000000000704 65.0
HKD3_k127_8930676_42 - - - - 0.00000001209 64.0
HKD3_k127_8930676_43 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K15342 - 2.7.7.49 0.00000002724 61.0
HKD3_k127_8930676_5 alpha beta hydrolase fold K03821 - - 5.499e-201 642.0
HKD3_k127_8930676_6 Serine aminopeptidase, S33 K03928 - 3.1.1.1 1.824e-194 620.0
HKD3_k127_8930676_7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) K07862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 550.0
HKD3_k127_8930676_8 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 508.0
HKD3_k127_8930676_9 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 501.0
HKD3_k127_8970555_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.756e-310 958.0
HKD3_k127_8970555_1 amp-dependent synthetase and ligase - - - 7.535e-262 864.0
HKD3_k127_8970555_10 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 430.0
HKD3_k127_8970555_11 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 376.0
HKD3_k127_8970555_12 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 366.0
HKD3_k127_8970555_13 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 346.0
HKD3_k127_8970555_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 306.0
HKD3_k127_8970555_15 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
HKD3_k127_8970555_16 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001447 214.0
HKD3_k127_8970555_17 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000001485 186.0
HKD3_k127_8970555_18 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000000000008695 176.0
HKD3_k127_8970555_19 DoxX family K15977 - - 0.00000000000000000000000000000000000000000005811 164.0
HKD3_k127_8970555_2 ABC transporter C-terminal domain K15738 - - 1.144e-213 716.0
HKD3_k127_8970555_20 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000000000003327 142.0
HKD3_k127_8970555_21 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000003924 104.0
HKD3_k127_8970555_3 metallocarboxypeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 603.0
HKD3_k127_8970555_4 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 565.0
HKD3_k127_8970555_5 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 508.0
HKD3_k127_8970555_6 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 474.0
HKD3_k127_8970555_7 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 439.0
HKD3_k127_8970555_8 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 455.0
HKD3_k127_8970555_9 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 444.0
HKD3_k127_9005639_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1118.0
HKD3_k127_9005639_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.32e-314 983.0
HKD3_k127_9005639_10 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 417.0
HKD3_k127_9005639_11 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 384.0
HKD3_k127_9005639_12 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 367.0
HKD3_k127_9005639_13 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 345.0
HKD3_k127_9005639_14 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 308.0
HKD3_k127_9005639_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000538 277.0
HKD3_k127_9005639_16 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018130,GO:0019438,GO:0033739,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000004424 223.0
HKD3_k127_9005639_17 Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000004007 230.0
HKD3_k127_9005639_18 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000002449 105.0
HKD3_k127_9005639_19 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000001937 85.0
HKD3_k127_9005639_2 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 6.375e-281 882.0
HKD3_k127_9005639_3 ABC transporter C-terminal domain K06158 - - 9.15e-241 761.0
HKD3_k127_9005639_4 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 529.0
HKD3_k127_9005639_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 524.0
HKD3_k127_9005639_6 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 505.0
HKD3_k127_9005639_7 Type II/IV secretion system protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 461.0
HKD3_k127_9005639_8 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 446.0
HKD3_k127_9005639_9 abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 414.0
HKD3_k127_9041198_0 - - - - 0.0 1539.0
HKD3_k127_9041198_1 - - - - 0.0 1276.0
HKD3_k127_9041198_10 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 346.0
HKD3_k127_9041198_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008841 294.0
HKD3_k127_9041198_12 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 267.0
HKD3_k127_9041198_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
HKD3_k127_9041198_14 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000009328 246.0
HKD3_k127_9041198_15 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD3_k127_9041198_16 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000000000001633 196.0
HKD3_k127_9041198_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000008289 181.0
HKD3_k127_9041198_18 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000003785 173.0
HKD3_k127_9041198_19 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000003008 167.0
HKD3_k127_9041198_2 Belongs to the peptidase M16 family K07263 - - 0.0 1044.0
HKD3_k127_9041198_20 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000000002128 151.0
HKD3_k127_9041198_21 addiction module antidote protein - - - 0.00000000000000000000000000001617 121.0
HKD3_k127_9041198_22 Transposase IS66 family - - - 0.0000000000001837 73.0
HKD3_k127_9041198_23 Domain of unknown function (DUF4936) - - - 0.00000001864 59.0
HKD3_k127_9041198_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.167e-257 814.0
HKD3_k127_9041198_4 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 488.0
HKD3_k127_9041198_5 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 478.0
HKD3_k127_9041198_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 411.0
HKD3_k127_9041198_7 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 345.0
HKD3_k127_9041198_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 351.0
HKD3_k127_9041198_9 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
HKD3_k127_9127263_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 582.0
HKD3_k127_9127263_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 576.0
HKD3_k127_9127263_2 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004717 265.0
HKD3_k127_9127263_3 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001901 178.0
HKD3_k127_9127263_4 Hemerythrin HHE cation binding domain K07216 - - 0.00000000007689 69.0
HKD3_k127_9127263_5 Protein of unknown function (DUF533) - - - 0.00008326 45.0
HKD3_k127_9142_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 2.825e-235 743.0
HKD3_k127_9153904_0 Zinc-binding domain of primase-helicase K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 437.0
HKD3_k127_9153904_1 Domain of unknown function (DUF932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006643 243.0
HKD3_k127_9239413_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.042e-215 683.0
HKD3_k127_9239413_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 3.049e-194 618.0
HKD3_k127_9239413_10 Thiopurine S-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001045 195.0
HKD3_k127_9239413_11 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000006064 190.0
HKD3_k127_9239413_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001646 181.0
HKD3_k127_9239413_13 BON domain - - - 0.000000000000000000000000000000000000000000491 168.0
HKD3_k127_9239413_14 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000000001889 158.0
HKD3_k127_9239413_15 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000001073 160.0
HKD3_k127_9239413_16 - - - - 0.00000000000000000000000000000001767 138.0
HKD3_k127_9239413_17 PFAM Sterol-binding domain protein K03690 - - 0.0000000000000000000000000000001156 132.0
HKD3_k127_9239413_18 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000005034 102.0
HKD3_k127_9239413_19 Type IV pilus assembly protein PilX C-term K02673 - - 0.000000000000000000462 94.0
HKD3_k127_9239413_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 608.0
HKD3_k127_9239413_20 - - - - 0.00000000000000004891 85.0
HKD3_k127_9239413_21 pilus assembly protein PilE K02655 - - 0.000000000000001055 91.0
HKD3_k127_9239413_22 Type II transport protein GspH K08084 - - 0.000000000000001112 85.0
HKD3_k127_9239413_23 Type II transport protein GspH K08084 - - 0.000000000000002309 90.0
HKD3_k127_9239413_24 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.000000007344 64.0
HKD3_k127_9239413_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 558.0
HKD3_k127_9239413_4 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 534.0
HKD3_k127_9239413_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
HKD3_k127_9239413_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
HKD3_k127_9239413_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006123 279.0
HKD3_k127_9239413_8 Eukaryotic integral membrane protein (DUF1751) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
HKD3_k127_9239413_9 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000023 211.0
HKD3_k127_9252473_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 513.0
HKD3_k127_9252473_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 336.0
HKD3_k127_9276725_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 549.0
HKD3_k127_9276725_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 444.0
HKD3_k127_9276725_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004508 281.0
HKD3_k127_9276725_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000002669 212.0
HKD3_k127_9293645_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000003399 186.0
HKD3_k127_9293645_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000009838 55.0
HKD3_k127_9360252_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 7.852e-220 683.0
HKD3_k127_9360252_1 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 280.0
HKD3_k127_9360252_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008614 269.0
HKD3_k127_9380418_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1127.0
HKD3_k127_9380418_1 Acyl-CoA dehydrogenase N terminal - - - 7.767e-273 850.0
HKD3_k127_9380418_10 Membrane K15977 - - 0.0000000000000000000000000000000000000000000005076 171.0
HKD3_k127_9380418_11 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.00000000000000000000000000000000000001543 162.0
HKD3_k127_9380418_12 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000004751 115.0
HKD3_k127_9380418_2 Patatin-like phospholipase - - - 5.798e-225 714.0
HKD3_k127_9380418_3 Belongs to the thiolase family K00632 - 2.3.1.16 4.1e-201 632.0
HKD3_k127_9380418_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 296.0
HKD3_k127_9380418_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007804 280.0
HKD3_k127_9380418_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000006435 247.0
HKD3_k127_9380418_7 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.000000000000000000000000000000000000000000000000000000000000001105 239.0
HKD3_k127_9380418_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HKD3_k127_9380418_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000008611 212.0
HKD3_k127_9524486_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 608.0
HKD3_k127_9647789_0 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 378.0
HKD3_k127_9647789_1 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 306.0
HKD3_k127_9647789_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001608 263.0
HKD3_k127_9647789_3 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000004216 199.0
HKD3_k127_9647789_4 Belongs to the peptidase S1B family - - - 0.00000000000000000000000000000004888 125.0
HKD3_k127_9647789_5 DNA integration - - - 0.0000003431 52.0
HKD3_k127_995991_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K03403 - 6.6.1.1 0.0 1121.0
HKD3_k127_995991_1 PUCC protein K08226 - - 2.238e-195 626.0
HKD3_k127_995991_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 526.0
HKD3_k127_995991_3 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 328.0
HKD3_k127_995991_4 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009322 298.0
HKD3_k127_995991_5 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000009709 197.0
HKD3_k127_995991_6 Photosynthetic complex assembly protein - - - 0.000000000000000000000000000004346 129.0